LOCUS       NZ_QFWQ01000009        22435 bp    DNA     linear   CON 06-MAY-2024
DEFINITION  Rhodanobacter denitrificans strain Yn1 D70275-2-02_R1_9, whole
            genome shotgun sequence.
ACCESSION   NZ_QFWQ01000009
VERSION     NZ_QFWQ01000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Rhodanobacter denitrificans
  ORGANISM  Rhodanobacter denitrificans
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Rhodanobacteraceae; Rhodanobacter.
REFERENCE   1  (bases 1 to 195980)
  AUTHORS   Yang,N., Mazhar,H.S. and Rensing,C.
  TITLE     Draft genome sequence of Rhodanobacter denitrificans Yn1 isolated
            from gold copper mine
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 195980)
  AUTHORS   Yang,N., Mazhar,H.S. and Rensing,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-MAY-2018) Institute of Environmental Microbiology,
            Fujian agriculture and forestry university., Fujian, Jinshan,
            Fuzhou, P.R. China, Fuzhou, Fujian 350000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Genomic Workbench v. 10.1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003335105.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 00:59:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,296
            CDSs (total)                      :: 3,243
            Genes (coding)                    :: 3,218
            CDSs (with protein)               :: 3,218
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 25
            CDSs (without protein)            :: 25
            Pseudo Genes (ambiguous residues) :: 0 of 25
            Pseudo Genes (frameshifted)       :: 6 of 25
            Pseudo Genes (incomplete)         :: 21 of 25
            Pseudo Genes (internal stop)      :: 2 of 25
            Pseudo Genes (multiple problems)  :: 4 of 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:29:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 35342
            Orig. end                         :: 57777
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QFWQ01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22435
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22435
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22435
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12435](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12435)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    125..134
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    197..206
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            654..1391
                     /locus_tag="DEO45_RS14150"
                     /old_locus_tag="DEO45_14150"
     CDS             654..1391
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007511742.1"
                     /locus_tag="DEO45_RS14150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14150"
                     /product="NrdJb"
                     /protein_id="WP_114344911.1"
                     /transl_table=11
                     /translation="MAIKIEKKITGYNVVKPEDKVAAAPVAAAAPKEAPTAEVIQMHES
                     VERPETLIGSTFKIKSPLFEHALYVTINDIVLNAGTKHEQRRPFEIFINSKNMDHFQWI
                     VALTRILSAVFRKGGDVTFIVEELKAVFDPRGGYFKAGGVYMPSIVAEIGSVVEQHMKN
                     IGLIHDPEMDEATRKLIAEKRAAYEALGAKKNADAGVTAESTSAETLTFPPGSMMCDKC
                     NTKALVLMDNCQTCLNCGYSKCG"
     gene            complement(1503..2453)
                     /locus_tag="DEO45_RS14155"
                     /old_locus_tag="DEO45_14155"
     CDS             complement(1503..2453)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006451193.1"
                     /locus_tag="DEO45_RS14155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14155"
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="WP_114344913.1"
                     /transl_table=11
                     /translation="MSTWPDQWDRRYIDRVRLLVEILPVLAQEPRFALKGGTAINLFEH
                     DLPRLSVDIDLAWLPVHDYAEDAASIAEALTRLAGALRARPLQLQVQLPASEGTSAVTR
                     LVASRGRARVQVETTPVMRGTVHPVRNMVVRPSVEEVFGFASMQVLGFGDLYAGKLAAA
                     LSRQHPRDLFDVGLLLEDERTDQVLWRTFLVYLTCSPKPAWEMLAPRMPVDFAATFDAH
                     FRGMTTQPVSAEALLENRERLLAHVSAWLDEPSCAFLRSVEEEQPDFRLIGFPHAVELP
                     AVRRKLRNLGQRTAAKRTADRACLEEVLARITGSR"
     gene            complement(2437..3231)
                     /locus_tag="DEO45_RS14160"
                     /old_locus_tag="DEO45_14160"
     CDS             complement(2437..3231)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011796424.1"
                     /locus_tag="DEO45_RS14160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14160"
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin"
                     /protein_id="WP_262982193.1"
                     /transl_table=11
                     /translation="MNRLLAELGDTRLVSSRWLRAHGYSSSLIVRYVASGWLVSPARGV
                     YMRKSGRLQWEGVVRSLQVGEGIALHVGGRFALTLQGYEHYLRLGDAGTITLYGPNGPP
                     GWVEKLPLKERFEFRGKGPFDPSVLRFSEMSEKMLLEQGLTWLRANAGVDALVCSTPER
                     AILELCDGVSGPALVYEADALMQAMTTLRPQRVGMLLRHCRSIKAKRLFLALAERHRHA
                     WLSHVPLDGVDLGRGKRALVPGGHLHPTYQITLPGDLDEHLA"
     misc_feature    3230..3244
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.59"
                     /tool="antismash"
     misc_feature    complement(3260..3273)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.31"
                     /tool="antismash"
     misc_feature    complement(3266..3279)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 19.08"
                     /tool="antismash"
     misc_feature    complement(3314..3327)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.64"
                     /tool="antismash"
     gene            3480..3740
                     /locus_tag="DEO45_RS14165"
                     /old_locus_tag="DEO45_14165"
     CDS             3480..3740
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DEO45_RS14165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DEO45_14165"
                     /product="hypothetical protein"
                     /protein_id="WP_114344915.1"
                     /transl_table=11
                     /translation="MSFATKSDAIDARRKIPASDVKKLGWRGVMRDVQKSGRVVATNHD
                     APEAVTRRTQSADAKRGRLREACVQHGVAGMEIQIGVLMQP"
     gene            complement(3759..3908)
                     /locus_tag="DEO45_RS16625"
                     /old_locus_tag="DEO45_14170"
     CDS             complement(3759..3908)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DEO45_RS16625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DEO45_14170"
                     /product="hypothetical protein"
                     /protein_id="WP_189339762.1"
                     /transl_table=11
                     /translation="MDPRIIELHCIMPMGNILSVLAHGILSYESTARLPHASVAMAEVQ
                     ERRD"
     gene            complement(4285..4569)
                     /locus_tag="DEO45_RS14175"
                     /old_locus_tag="DEO45_14175"
     CDS             complement(4285..4569)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006452338.1"
                     /locus_tag="DEO45_RS14175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14175"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_223250887.1"
                     /transl_table=11
                     /translation="MAEKGPLPVYSRRLREAREALDISQRTLGIKAGLDEFVASTRVNR
                     YETGVHQPDLQTLQRLAAVLKLPVAYFYAEDDELAQLIANFKGRSKGRR"
     gene            complement(4824..5144)
                     /locus_tag="DEO45_RS14180"
                     /old_locus_tag="DEO45_14180"
     CDS             complement(4824..5144)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006452338.1"
                     /locus_tag="DEO45_RS14180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14180"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_114344917.1"
                     /transl_table=11
                     /translation="MTEKCPANIYGRRLREARNSYGLSQEKLGIAARLDQSVAGSRVSR
                     YETGKHEVKLGLQKLFAKALALPLKYFYIEDDEEARLIAEASRSDKPVKLKEAIERKLK
                     GK"
     misc_feature    complement(5076..5078)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(5269..5283)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            5421..7826
                     /locus_tag="DEO45_RS14185"
                     /old_locus_tag="DEO45_14185"
     CDS             5421..7826
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1082:
                     TonB-dependent siderophore receptor family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015446673.1"
                     /locus_tag="DEO45_RS14185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14185"
                     /product="TonB-dependent receptor"
                     /protein_id="WP_114344918.1"
                     /transl_table=11
                     /translation="MKTNTLRNAISIALFAAAAGANGWAVAQDATTGTATQGRASVAKA
                     STRTQQKKPTDKSAAPAAINLQTVTVTVTGTRIRGGTTPSPVITIGSEQIQQEGFTDLG
                     EVIRSVPQNFSGGQNPGVIGTTGGIGNGDFTGGSALDLRGLGPDASLTLLNGHRLVYDG
                     YSQGLDISAIPVEAVERLEIVPDGASAIYGSDAVGGVANVILKRDFDGVTLGARYGGAT
                     EGGLATREYTATAGTTWASGGLIATFKDVDVDPIYARQRSYTRYLIDPYTIYNGSNLRS
                     GLVSVHQSMGDVAELRLDALRTERDTTEYLGLTANSYNRYNPSTSIGLISPSVEFFLRN
                     DWSITLGGTYGKDDTIFASHLVSAAGSRLTTQTCYCNEGRSWELGAEGPLFPAGGGEAR
                     LAVGIGSRTNKFRTVPKVSGSAYGGEEQARFAYAELSVPFVSPASDIPGVHRLEFSAAM
                     RGEEYASFGRVATPKLGVIYDPTADVTFKTSWGKSFKAPTLLQRYQSKVAYLWKASAVG
                     AGGSPADATALESYGGNTDLGAERARTWTASLALHPEALPGLDAELTWFDIDYTDRVVE
                     PLITRQALSNPAYAGFVNRSPTPEQVQDLLAVYNSAFYNLSGVAYDPSKVVAIIHDQYV
                     NAARQRIKGLDLSGLYRFDLGGGQLTVRGSASWLDSAQTTSAGQPKQALAGTAFNPARL
                     NSRVGAVWTSGGFSASGFVNYTGGVTNRLATMTEKTASFTTLDSTINYDLGERAGPLSG
                     LTLGLSVQNLLNRAPPLYTSAVAIFVPYDATNYSAIGRFVSVSVSKHW"
     misc_feature    6351..6353
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7086..7088
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7671..7673
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7836..10016
                     /locus_tag="DEO45_RS14190"
                     /old_locus_tag="DEO45_14190"
     CDS             7836..10016
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007511732.1"
                     /locus_tag="DEO45_RS14190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14190"
                     /product="Atxe2 family lasso peptide isopeptidase"
                     /protein_id="WP_114344919.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 6.8e-11, bitscore:
                     35.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLSLSTGLEDGCADGVRLDSSTRKLPTCWVSAFAFIVLVAAAVG
                     LLHAETISPRRLLEVTDLSNPVISPSGRYVAFRAEQASIERNMYDTTWYVQALDGKSPL
                     LRVADGGAPLRDYLSGIVLSSQAVWSPDGKWIYYRARLDGRVSVWRAAANGSGARAVTP
                     DPADVRDFKLSGDGQTLTYSVGPTREDVIAAEESEYDRGIRIDDSVFIADGLFRSSKVN
                     GRPTTLRFLGGWFSLGPLLAKEPGRWKSVDLATMTTRDLSASERPARPLTPADLSPDLP
                     AAPTKIAQHPDDGRIAVLLPGRKDKSLLMSRYVELAMLPDRHASRPIRCIAKLCRHRDI
                     TDIQWRTGSDEILFTTIDNAKAQSVYGWNVATDTVRPIVLSNGLLSGSQLYWDSPCTLS
                     ADTLVCIAAEADHPPHLEAIDVASGHRRILFAPNKGLEADILAMAPAKLIRWKDAQGRE
                     FTGQLFEARGARTGHPPPLFVTFYSCYGFLRGGVGNEWPLATLAEGGISALCINALPGF
                     QLDTVAHYDQGRAAIESVVTLLSAEGRIDRTRVGMGGLSYGSEVTLWTLAHSDVVSAAS
                     VSGTSVTPTYYLFNSLQDAFRPTLRKLWQLGAPNETPKRWKEVSPVYQLDRIRAPILFQ
                     MPEREYRMTLDYALPLMRRHQADIYAFPDETHVKFQPKHKLAVYERNVDWFRFWLQDYE
                     DPSPDRAGQYRIWRGMKKAAKSRFGAGAHDGS"
     misc_feature    7848..7850
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9120..9122
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..11749)
                     /locus_tag="DEO45_RS14195"
                     /old_locus_tag="DEO45_14195"
     CDS             complement(10001..11749)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007511730.1"
                     /locus_tag="DEO45_RS14195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14195"
                     /product="asparagine synthase C-terminal domain-containing
                     protein"
                     /protein_id="WP_114344920.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.8e-28, bitscore:
                     93.7, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYRYIIFLGERLKRSTDYTLQLNRLLRAEGMICKLESASVGVFA
                     SIDVPTLTIHGHGLLIGQVFTKDGQLISQPLDIDGSVRELTSRLLQNTWGNYLAIFCDR
                     DNPSATTLLRDPSGAVPCVYSLADGEGFITSDIDLAVDLGLYRSEVNWQAIAHGLTFPY
                     LKTARTALQRVRELLPGNMLACQGRDVSVRSAWSPWRFVEKGIRHTDPHVAAEDVRDAV
                     SSAVRALSTSNDRFLVELSGGLDSSVVAACLRHALPRAIFCTLVMPVAGTDERPYARLV
                     TEALGQELFPVEVGFNNARFEFPVPRSSVVPAVGILQNATNEAWEAVGTLYGVDGYFSG
                     DGGDTVFCYLKTAAPAADAFRECGTMAGIAAIGDLATLHECTVFKASRLALKKLLRRPH
                     TAWKEDRTLLNPAWVTTVPEHHPWMEAPPNALPGDRERIHDLVGTQLFRDATLRAAGHS
                     THFPLLSQPVMEACLNVPTWMWIAGGRNRTVARQAFADLLPRTILDRRSKGSYTGYMAA
                     IYMRNKLKIREFLEGGQLCAHDLLDRSALADFFAKDLAPRDLSFLRLFDLCAAENWVRQ
                     QGHDPS"
     misc_feature    complement(10457..10459)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11063..11065)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11749..12435)
                     /locus_tag="DEO45_RS14200"
                     /old_locus_tag="DEO45_14200"
     CDS             complement(11749..12435)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007511728.1"
                     /locus_tag="DEO45_RS14200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14200"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_114344921.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 7.8e-17,
                     bitscore: 54.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF13471 (E-value: 2e-21, bitscore: 69.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHYRLRENLSYCDVDGHLIFLDVAQDRYFKLTGALENAMRRFQAH
                     EDIAPTLVDGLVTARILVEAPNLKGRTAIANIRRPTCSAIEQPATIASQRIDMAIVFEV
                     MAIVWSTRRQLKTRALKTNLDEARAYRDRKTGAHEIATPAAPEDNLLQATGQFARARRY
                     VPIEPICLLDSLSLLRFLSRRGLSVNIIFGVTPDPFAAHCWVQAGDIVLNETLSDAHAH
                     TPIRMV"
     aSDomain        complement(12238..12435)
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DEO45_RS14200_Lasso_Fused_RRE.1"
                     /evalue="1.20E-17"
                     /identifier="RREFam003.1"
                     /label="DEO45_RS14200"
                     /locus_tag="DEO45_RS14200"
                     /protein_end="66"
                     /protein_start="0"
                     /score="54.7"
                     /tool="antismash"
                     /translation="MHYRLRENLSYCDVDGHLIFLDVAQDRYFKLTGALENAMRRFQAH
                     EDIAPTLVDGLVTARILVEAP"
     gene            complement(12486..12632)
                     /locus_tag="DEO45_RS14205"
                     /old_locus_tag="DEO45_14205"
     CDS             complement(12486..12632)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033522.2"
                     /locus_tag="DEO45_RS14205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14205"
                     /product="benenodin family lasso peptide"
                     /protein_id="WP_189339763.1"
                     /transl_table=11
                     /translation="MDTNENIRSNAQDDVIELGVASVETKGPGPSNEGTGQGIPFVPGI
                     SEE"
     CDS_motif       complement(12555..12632)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MDTNENIRSNAQDDVIELGVASVETK"
                     /locus_tag="DEO45_RS14205_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(12498..12554)
                     /prepeptide="core"
                     /locus_tag="DEO45_RS14205_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="12.70"
                     /molecular_weight="2108.2"
                     /monoisotopic_mass="2107.0"
                     /core_sequence="GPGPSNEGTGQGIPFVPG"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MDTNENIRSNAQDDVIELGVASVETK"
                     /leader_location="[12554:12632](-)"
                     /tail_sequence="ISEE"
                     /tail_location="[12485:12497](-)"
     CDS_motif       complement(12486..12497)
                     /locus_tag="DEO45_RS14205_lassopeptide"
                     /note="tail peptide"
                     /note="lassopeptide"
                     /prepeptide="tail"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     misc_feature    complement(12692..12707)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.5"
                     /tool="antismash"
     misc_feature    complement(12695..12708)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.37"
                     /tool="antismash"
     gene            complement(12803..13423)
                     /locus_tag="DEO45_RS14210"
                     /old_locus_tag="DEO45_14210"
     CDS             complement(12803..13423)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008437214.1"
                     /locus_tag="DEO45_RS14210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14210"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_114344923.1"
                     /transl_table=11
                     /translation="MDSKSAFVYGQVRRALQAGRYAPGQRIDPATLASEYKTSHTPVRF
                     ALYRLVGEGMVTDHARNGLHVPLLNEVALRNLYDWMERLLLMACDIGEAPTFQKTGKLE
                     LATADGDLVKLTWQLFDAIARATAHEPLHHAVKRANDRLAPIRRAKQELFEHTGEELSQ
                     LNLHWQARDMPALKSALRDYHERRKQLVPSIVALLSDRCGYFS"
     misc_feature    complement(13220..13222)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    13580..13595
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            13886..14173
                     /locus_tag="DEO45_RS14215"
                     /old_locus_tag="DEO45_14215"
     CDS             13886..14173
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DEO45_RS14215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DEO45_14215"
                     /product="hypothetical protein"
                     /protein_id="WP_147269701.1"
                     /transl_table=11
                     /translation="MRIGSGLQAVARLALVCLLASFSAHAAGSDSTSIDCNADHCGLLA
                     DGAYPNLVIGRLDHVDTAVDMARAFHWAEKQESECRFQGGRLKVDSDPDF"
     misc_feature    14579..14592
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.54"
                     /tool="antismash"
     misc_feature    complement(14639..14654)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.44"
                     /tool="antismash"
     gene            15022..19083
                     /locus_tag="DEO45_RS14220"
                     /old_locus_tag="DEO45_14220"
     CDS             15022..19083
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03696.1"
                     /locus_tag="DEO45_RS14220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14220"
                     /product="DUF6531 domain-containing protein"
                     /protein_id="WP_189339764.1"
                     /transl_table=11
                     /translation="MLGNPVNISTGNKFEDETDFEGFGSFPLTFHRYYNSASFGGDGTL
                     GVQWTHTFSRSLVLQSSTEAKLFRDNGEIRYFNKCGSLWCATPDEVGSLLEFTAGNGAI
                     TGWQYTDENKIVEVYNSDGTLRSETNRDGLSLVLAYDATDRLSTVTDSFGRQLALTYNS
                     TNQVAQLKAPDGGISTYAYDASGNLSSVTHPGNTTRTYFYNESGNVGTGAGPNLLTGIQ
                     DESGQRFATFQYDGQSRATISEHANGAGAIQLTYNADGSTTVLNASGDSKAYAFQTVQN
                     VNHTATVNGSACADCGINSRYAYNSAGDLTSTVDFNGNTTHYSIDAAHLEESRIEASGT
                     PMQRTINTAWNTALRVPLTRIVTDANSNVVSSISWVYNTVGQPLARCEIDPAQASSYAC
                     ATTGTPPAGVRRWTYSYCTAVDTTQCPIVGLLLAVDGPRTEVADVTTYTYYLTDSTTVH
                     HGDLQSVTDALGHTTSYLTYDGAGRVTSLQDANGVVTNLTYTPRGWLASRSVGGATTTL
                     AYTAYGAVASITDPDGVTTHYTYDAAHRLTDITDAQGNVVHYTLDNAGNKTGEQIRTAS
                     GTVVHSLSRTFNALGQLTAVVDGLNHIVFNAGTSGSYDGNGNLVQSTDALGIQRVQGFD
                     ALNRLQSTIANYNGTDPATKNTQSVFAYDARDNLEGVGDPDGLNTTYDYDGLGNRTALH
                     SPDTGTSSDTYDAAGNRLMHIDAKGIVSTSTYDANNRLISTGYADTTLNVSYAYDEANA
                     VTGCSASRPIGRLTRVVEAGVTTVFCYDGRGNVIQKRQVTASQTDTTFYTYTAGDRLSS
                     VSAPDQTAISYAYDSDGRVSSVQVVPAGTSTAPPTVVSNISYLPFGPISSYTLGNGQVV
                     TRAYDANYRLTDLTSQALNLHFNRDAMGNIVALGNAPGANPATEAYSYDPLYRLTGITD
                     NGAALESYTYSQTGDRRSKTASGLATGVYLYTSGTHQLASINGISRANDANGNTTGSVI
                     GGNTYGFGYNGRNRLTVAQLNGATVGTYTYNAMGQRIGKVATFPQATTERYAYNEAGQL
                     IGEYGTSSTTLSKGNGKHQGKHHQHAGTVVTNNRDYVWLGDIPLAVIDNTINGSVTTSV
                     VNYVHVDGLGTPRAVTDGAGTMIWSWPYVGNPFGQQAPTSTTGYVLNLRYPGQYFDSER
                     GLAYNVNRDYEAATGRYIQSDPIGLAGGLASYSYVDSSPLQDIDLLGLKKVILFGERDS
                     VFLQRAHEYKDDPNACLVYSHGSPSFIYDTRGDTTKRMDDPQQIVNLLKTEGCTSNMPV
                     IIYACRTGMGDNSIAEDISKTGAFPSVTAPTSYVWYNQDPTSTGPSLIFGKNANSTMDT
                     DSPGTMRTFP"
     misc_feature    15103..15105
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15583..15585
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19080..19457
                     /locus_tag="DEO45_RS14225"
                     /old_locus_tag="DEO45_14225"
     CDS             19080..19457
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DEO45_RS14225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DEO45_14225"
                     /product="hypothetical protein"
                     /protein_id="WP_147269702.1"
                     /transl_table=11
                     /translation="MTRKNQTISRVLATLLLSSIVLIGCAAHATQEAAVPTPGERFSIS
                     QSELPKVKDQAAHGDVSAINKLVDYYMLYLGDEDQGILWLERLGDTGDTEARKNVLTFY
                     QRHPSANNTKHLELLKARWGM"
     misc_feature    19425..19427
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    19718..19731
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.39"
                     /tool="antismash"
     misc_feature    complement(19791..19806)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    19917..19931
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.67"
                     /tool="antismash"
     gene            19925..20362
                     /locus_tag="DEO45_RS14230"
                     /old_locus_tag="DEO45_14230"
     CDS             19925..20362
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017462438.1"
                     /locus_tag="DEO45_RS14230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DEO45_14230"
                     /product="DUF2846 domain-containing protein"
                     /protein_id="WP_114344927.1"
                     /transl_table=11
                     /translation="MFKKLLSAFVLTGVLVVSGCASVPMAGQSADMQAKSFTPSADKAT
                     VYIYRNENFGAAIKMPVLIDNAAVGDTAAKTYIEKQLPAGTHTITSKTEKDSSVTIDML
                     AGQIYYVWQEVKMGMWAARSALHVVDAKKGQAGVRESKLIQ"
     misc_feature    complement(20461..20479)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.41"
                     /tool="antismash"
     gene            20496..20636
                     /locus_tag="DEO45_RS16630"
     CDS             20496..20636
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DEO45_RS16630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_189339765.1"
                     /transl_table=11
                     /translation="MLTMLFGIDFIIVASIAGRWRHAQRVHFQTQKHGNKGPEWNGPVT
                     Q"
     gene            20658..21107
                     /locus_tag="DEO45_RS14235"
                     /old_locus_tag="DEO45_14235"
     CDS             20658..21107
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DEO45_RS14235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DEO45_14235"
                     /product="hypothetical protein"
                     /protein_id="WP_114344928.1"
                     /transl_table=11
                     /translation="MTRPFVIWVTVVLSVLLGVSAAFGLLKVILQVPMGLGPNSAIPVW
                     RVLLMVAIQAVATMFLAAVVYAAFARPRWGRAVCAVFAVLLALMVLYAGFHPDPHPLFA
                     IKSGAEEAGAVVGRLMMCVLFGVYAYKMVIGTKVRAYFLSTEGRK"
     gene            21197..21694
                     /locus_tag="DEO45_RS16515"
     CDS             21197..21694
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DEO45_RS16515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_147269703.1"
                     /transl_table=11
                     /translation="MVDDWSGMMPDSKTWVWLSMAVLLAACGHPGEPAYPPGPDVQFHL
                     GTFEARSGYRLAELPSGVHAIHLDPNIVVGTRDIAYVRDGGCLDGACSVDFRFSPEGGK
                     RMLRVSEAAIGRQMAIVVDGKVVSVADISGPIRDGLRLSTTSEEESQALIRQIAVVPQH
                     VD"
     misc_feature    21266..21268
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    21371..21373
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 acgtgccacc ggcggcgccg gttgccgcac ccgcaccggc gaagaagaag ccggcggcga
       61 agaaggccgc tccgaagaaa gccgcggcca agaaggcagc gccgaagaag gccgccgcca
      121 agaagaaggc ggcgccgaag aaggctgctg cgaaaaaggc cgcgccgaag aaggctgcgg
      181 ccaagaaagc cgtgaagaag gcggcgaaga aggttgcgaa gaaagcggcg gtgaagaaga
      241 ccgccgcgaa gaaggccgtg aaaaaggccg tcaggaaagt cgccaagaag gccggcgccg
      301 cgaagaaggc ggtgaagaag gtcgcgaaga aagtcgccaa ggtggtgaag aagaaagccg
      361 ccaaggtcgc aaggaaggtc agcagcaaga agacggccgg caagaaggcc gcaccgaaaa
      421 aggcggcagc gaagaagtcc gccagcaaga aagccgtcgc caagacggcc aagaggtcca
      481 ctgccagcaa gaaggcgagc gtcaagtcgg ccgcgcgcaa gcccgccgcc aagaaggccg
      541 ccggcaagaa gaagtaagca gcaccgcatc cggcccggcc gaagcgccgg gccggatgat
      601 ccacgcagca cgccgcgtcc actccggcac caacacccaa agaagcgaac accatggcga
      661 tcaagatcga aaagaagatc acgggttaca acgtggtcaa acccgaagac aaggttgccg
      721 ccgccccggt cgctgccgcc gcgccgaaag aggcgccgac ggccgaagtg atccagatgc
      781 acgaaagcgt ggagcgcccc gagaccctga tcggctccac cttcaagatc aagtcgccgc
      841 tgttcgagca cgcgctgtac gtcaccatca acgacatcgt gctcaacgcc ggcaccaagc
      901 acgagcagcg ccgccccttc gagatcttca tcaactcgaa gaacatggac cacttccagt
      961 ggatcgtggc gctcacccgc atcctctccg ccgtgttccg caagggcggc gacgtcacct
     1021 tcatcgtgga agagctgaaa gccgtgttcg acccccgcgg cggctatttc aaggccggcg
     1081 gcgtctacat gcccagcatc gtcgccgaga tcggctcggt ggtggagcag cacatgaaga
     1141 acatcgggct gatccacgac ccggagatgg acgaggcgac gcgcaagctg atcgccgaga
     1201 agcgcgcggc ctacgaggcg ctgggcgcaa aaaaaaacgc tgacgctggc gtaactgccg
     1261 agtcgaccag cgccgaaacg ctgacctttc cgcccggctc gatgatgtgc gacaagtgca
     1321 acaccaaggc gctggtgctg atggacaact gccagacctg cttgaattgc gggtattcga
     1381 agtgcgggtg atgcccggtt tgcgcgaata gaaaaggcga cgcccccgct ttgagtggcg
     1441 gggcggtcta ccgttcgagg tcagcttgaa gcagtcggcc acagtcttgg cgacgccgta
     1501 cctcatcgcg aaccagtgat ccgcgccagc acctcctcca aacaggcgcg gtccgctgtg
     1561 cgtttggcag cagtacgctg ccccaggttt ctcagcttgc gcctcacggc cggcagttcg
     1621 acggcatgcg ggaacccgat caagcgaaag tctggctgct cttcctccac ggaccggaga
     1681 aaggcgcagg acggctcatc cagccacgca gagacatgcg caagcaagcg ttcgcgattt
     1741 tccagcagag cttccgcact gacaggctgg gtcgtcatgc ccctgaagtg cgcgtcgaag
     1801 gtcgcggcga aatccacggg catacgcgga gccagcattt cccaggcagg cttggggctg
     1861 caggtcaggt acacgaggaa ggtccgccag agcacctggt cagtccgctc gtcctccagc
     1921 aacaggccaa catcaaaaag atcgcggggg tgctgccgcg acagtgccgc agccagcttg
     1981 ccggcataga gatcgccaaa gccaagcacc tgcatcgagg cgaagccgaa tacctcctct
     2041 acgctcggcc ggaccaccat attgcgcact ggatgcaccg taccgcgcat gacgggggtg
     2101 gtctcgactt gaacgcgcgc gcgtccacga ctggccacta gccgcgtgac cgcactcgtc
     2161 ccctcgcttg ccggcaactg cacctgcagt tgcaaggggc gggcgcgcag cgcgccagcc
     2221 agtcgcgtga gtgcctccgc aatcgatgcc gcgtcctcgg catagtcatg caccggcagc
     2281 caagccagat cgatgtccac cgacaagcgt ggcaggtcgt gctcgaacaa attgatggct
     2341 gtaccaccct tgagcgcaaa acgaggctcc tgcgccagca ctggcaggat ctcgaccaac
     2401 aagcgcaccc ggtcgatata gcgccgatcc cactggtcag gccaagtgct catcaaggtc
     2461 gcccggcaag gtgatttgat aagtcggatg caggtgcccg ccgggcacta gtgcgcgctt
     2521 gccccgtccc aggtcgaccc catcgagagg cacgtgcgac agccacgcgt gtcggtggcg
     2581 ttcagcgagg gccaggaaca gccgcttggc cttgatgcta cggcagtggc gcaagagcat
     2641 accgacccgt tgtggccgca gcgtggtcat ggcctgcatc agcgcatcgg cctcgtagac
     2701 cagcgctggc cccgagacac catcacacaa ctccaatatg gcccgctctg gtgtggagca
     2761 caccaaggca tccacgcccg cgttagcccg aagccaggtg agtccttgct ccaacagcat
     2821 cttctcggac atctccgaga accgcaggac agacggatcg aatggcccct tgccccggaa
     2881 ctcgaagcgc tccttcagcg gcagcttttc cacccagccc ggcggcccgt ttggtccgta
     2941 gagggtgatc gtccccgcgt cacccaggcg cagatagtgc tcgtacccct gaagggtcag
     3001 cgcaaagcgc cccccgacat gcagcgctat gccttcacca acctgcaggc tgcggaccac
     3061 gccttcccat tgcaggcgac cgctcttgcg catgtagacg ccgcgcgccg gcgacaccag
     3121 ccaaccgctg gccacgtagc gcacaatgag gctgctggag tagccgtggg cccgcagcca
     3181 gcgactggaa accaggcgcg tatcgcccaa ttcggccagc aatcggttca attttcctat
     3241 attttgctca ctcatagtgt tctaattata ctattcataa acctccgtca agatgtcgta
     3301 gtttaaattt cgcgtaaaat agttatccag agtgatcttt tcaggataaa aacaaaccac
     3361 gcgctgcttc aagcaactgc ctgccgcgaa gcgccttgcc cgagacatgg cgccttggca
     3421 taaatgggcc atttgggcca ttttgggtac catggaccag gatcgacgca ggagaccccg
     3481 tgtcctttgc cacaaaatcc gatgcaatcg atgcccggcg gaagatcccg gcgtccgatg
     3541 tgaagaagct tggctggcgc ggcgtgatgc gcgatgtcca gaagagcggg cgcgtcgtgg
     3601 cgaccaatca cgatgcgcct gaggcggtca cccgcaggac gcaaagcgcg gacgcaaagc
     3661 gcggacgctt gcgcgaggcg tgcgtacagc atggggttgc gggcatggaa atacagattg
     3721 gcgtactgat gcaaccgtag tgcgccggga acctgttttc agtcgcggcg ttcctgaacc
     3781 tccgccatgg cgacagaggc gtgcggcagc ctggctgtcg attcgtacga gagaatgccg
     3841 tgagccagga ccgaaaggat attgcccatc ggcatgatgc agtgcagttc gatgatgcgt
     3901 gggtccacgc tgcaggtcac tcccgaaggg tgcctcattg tgccctagcg gttgagcatg
     3961 acgtcaattc ggaaaggaag ccgagccggg ggaatcgatt gcggacccgg tgctgatcct
     4021 ggccctgccc gaagggaagg accttctccc ggacacggtc gccgcccagg cgacgcccga
     4081 ctgggtcagg ccactgatcg aagcagtcct gatcgaatat gggtagacac gccgttcgta
     4141 tgacgcgtag ttgcgtacct ccgatctcgt gagcccacaa gggtggagga ataaagtcgc
     4201 aacgggcgcc ggtccctcga cttgcttgcc gtcgaggcgt ccggtgtgga agtccccaac
     4261 tcgtacctac ttggcagcct ccgatcagcg cctgcccttg cttcgcccct tgaaattggc
     4321 aatcagctgc gcaagttcgt cgtcttcggc atagaagtag gccaccggca gcttgaggac
     4381 cgctgcgagg cgttgcaggg tctgcagatc gggctggtgt acgcctgttt cgtagcggtt
     4441 gacgcgcgtg ctggcgacga attcgtccaa gccggccttg atgcccaagg tgcgttgtga
     4501 gatgtcgagg gcttcgcgtg cctcgcgcag ccgacggcta tatacgggga gcgggccctt
     4561 ctcagccacg ggcgcatgtg tcttgagctt ccatgtaggg aagcttccgg atacatgtgg
     4621 gaatgtgata ctacggtaaa cgtagtgatc ttctggcctg ccgagaagct ccgctgggag
     4681 gcgctgggac tcgtttggtc aagtgggcat gatggccgcc acggccggcg atcgcatggc
     4741 ggtcttactt ctcaagcatg tcgcttacgc gtgggcatga ttcaagccag gaggatggcg
     4801 agagcctgct cccgacggcg gctctacttt cccttcagct ttctctcgat cgcctctttc
     4861 agcttgaccg gcttatcgct gcgcgaagct tccgcgatca gtcgcgcttc ctcgtcgtcc
     4921 tcgatgtaga aatatttcaa aggcagtgcc aaagccttgg cgaacaattt ctgcagtcca
     4981 agtttcactt cgtgcttgcc cgtctcgtag cggctgacgc ggctgcccgc tactgactga
     5041 tcaagcctcg ccgctatccc cagcttctcc tgagataagc catagctatt ccgtgcctcg
     5101 cgtaggcggc ggccgtagat gtttgccggg cacttttcgg tcataggcgc atatcagttt
     5161 cgatatgcag cagcttcccg acgggcgctt gacattgata ctacgtaaaa cgtagtgtta
     5221 acaaagctac gtttatcgta gccatggggc tttttgctgg cgatctggtg caaatgcaat
     5281 ccagccggag ccggtgaggg gtgaagacag acgtggcggc ttagctggcg gcaggtttgt
     5341 acgcgctgag aagcgcgttt cgagcctgtg atcaagcagc gaccggcaac gcgtcaatca
     5401 ggggaaagca aaggatcagc atgaagacaa acacgctacg caacgccatt tccatcgcct
     5461 tgttcgcggc cgctgccggc gctaacgggt gggccgttgc ccaagacgcc acgacaggca
     5521 cggccacgca gggtagggcg tcggtggcca aggcgtcgac taggacgcaa caaaaaaaac
     5581 cgaccgacaa gtccgcggcc ccagcggcca tcaatctgca gaccgtgacc gtgaccgtca
     5641 ccggcacgcg catccgcggc ggcaccacgc cctcaccggt cattacgatc ggtagcgagc
     5701 agatccagca agaaggtttc accgacctcg gcgaggtcat ccgcagcgtg ccgcagaact
     5761 tctctggtgg gcagaacccg ggcgtgatcg gtactaccgg tggcattggc aatggggatt
     5821 tcactggcgg ctccgcgttg gacctgcgcg gattgggtcc cgacgcatcg ttgacgctgc
     5881 tcaatgggca ccgtctggtc tatgacgggt attcccaggg gctggacatc agcgccattc
     5941 cggttgaggc ggtcgaacgc ttggaaattg tcccggatgg tgcatcggct atctacggct
     6001 cggatgcggt gggcggtgtg gccaatgtga tcctcaagcg cgatttcgat ggggtgacct
     6061 tgggggcgcg ctacggcggc gcgaccgaag gcgggctggc aacgcgggag tacaccgcga
     6121 ccgccggcac cacctgggcg agcggtgggt tgatcgcaac tttcaaggat gtggatgtcg
     6181 atcccatcta tgcgcgccag cgcagttaca cccggtatct gatcgacccg tatacgattt
     6241 acaacggcag caacttgcgt agtggtctag tcagcgtgca ccagtcgatg ggcgacgtgg
     6301 ccgaattgcg acttgacgcg ctcaggaccg agcgtgacac gacggaatac ttaggcctga
     6361 cggccaattc ctataaccgc tataacccga gtacgtcgat cgggttgatc tcgccaagtg
     6421 tcgaattttt tcttcgaaat gactggtcca tcactctcgg tggaacgtac ggcaaggacg
     6481 acaccatctt tgcgagccat ctcgtgtcgg cggcgggaag cagactcaca acccagacgt
     6541 gttactgcaa cgaaggccgc tcttgggagc tcggcgccga gggtccgctg ttcccggcgg
     6601 ggggagggga ggcacgcctg gccgtcggta tcgggtcgcg gacaaacaaa ttccggactg
     6661 tgccaaaggt gtccggaagc gcttacggcg gcgaggaaca ggcgcggttc gcctacgccg
     6721 agctgagtgt tccgtttgtt tcgcctgcct cggatattcc aggcgttcat cgcctggagt
     6781 tcagtgctgc gatgcgtggc gaggaatacg ctagttttgg ccgggtagcc acgccgaagc
     6841 tcggggtgat ctacgacccc accgccgacg tcacgttcaa gacctcttgg ggaaaatcgt
     6901 ttaaggcacc cacgctgctg cagcgctacc agagcaaggt cgcctacctg tggaaagctt
     6961 ccgcggtagg cgcgggcggc agtcccgccg atgcgaccgc attggagtcc tatggtggta
     7021 acaccgactt gggtgctgag cgggcgcgga cctggacggc ctcgttggcc ctgcatccgg
     7081 aagcattacc ggggctcgat gccgaactaa cctggttcga catcgattac accgaccggg
     7141 tggttgaacc gctcatcacc cggcaggcgc tgagtaatcc agcctatgcg ggctttgtga
     7201 atcggtcgcc gacgcccgag caggttcagg atcttctcgc cgtctacaac agcgccttct
     7261 acaacctatc cggcgtcgcc tatgacccga gcaaagtggt ggcgattatc cacgaccagt
     7321 acgtgaatgc ggcacggcag cggatcaagg gtctcgatct gtccggtttg taccgcttcg
     7381 atcttggcgg aggacaactg acggtgcgtg gatcggccag ttggctcgac agtgcacaga
     7441 cgaccagcgc cggccaaccc aaacaagcgc tcgctggcac tgccttcaat ccggcccggc
     7501 tcaatagccg tgtcggtgca gtgtggacat cgggaggttt cagcgcgtcg ggcttcgtca
     7561 actacaccgg cggcgtgacc aaccgtcttg cgacgatgac ggagaagacc gcgtcgttca
     7621 ccacgctgga tagcacaatc aactacgacc tcggtgagcg tgctggcccc ttatcggggc
     7681 tgacgctcgg tttgtcggtg cagaacctgc tgaatcgcgc gcctccgctt tatacctcgg
     7741 cggtggcgat ttttgtgccg tacgacgcta ccaactactc ggcgatcggg cgtttcgtca
     7801 gcgtctcggt ctccaagcac tggtaggggt agatcatgaa tctttcttta tcgaccggcc
     7861 tcgaggacgg ttgtgccgac ggggtgcgtc tggattcctc gacaaggaag ctccctacgt
     7921 gttgggtttc ggcgtttgca tttatcgtac tggtcgcggc tgccgtcggg ttgctgcatg
     7981 cggaaacgat ttcgccgcgg cgcctgttgg aggttaccga tctgagtaac ccggtgatct
     8041 cgcccagtgg acggtacgtg gccttccggg ccgagcaggc atcgatcgaa cgcaacatgt
     8101 acgacactac ttggtatgtg caagcccttg atgggaagtc tccgctgctt cgtgtggcgg
     8161 atggcggtgc gccgttgcgc gactacctca gcggtatcgt gctgtcatca caggccgtat
     8221 ggtcgccgga tggaaagtgg atctactatc gcgcccgcct cgatggccgc gtctccgtct
     8281 ggcgcgccgc agcgaatggt tccggggctc gcgcggtgac accggacccg gcagacgtgc
     8341 gggatttcaa gctgagcggt gatgggcaaa cgctcacata tagcgtcggt ccgacacggg
     8401 aagacgtcat cgccgccgaa gagtccgagt acgatcgtgg cattcgcatc gatgactcgg
     8461 tgtttatcgc tgacgggctg ttccggtcga gcaaagtcaa tgggcgaccg actacgctgc
     8521 ggttcctggg aggatggttt tcgctcgggc ccttgctggc aaaagagccg ggccgttgga
     8581 agtctgtcga cttggcaacg atgacaaccc gagacctgtc cgcatcggag cggccggcgc
     8641 gtccgctgac gccggccgat ctttcgcccg atctgccggc ggcgccgacc aagatcgccc
     8701 agcatccaga cgatggacgc atcgcggtac tgttgcccgg gcgtaaggac aagagtctgc
     8761 tgatgagccg gtatgtcgag ttggccatgc tgccggacag acatgcttcg cgtccgattc
     8821 gttgcatagc caagctatgc cgtcatagag acattacgga tatccaatgg cggaccggga
     8881 gcgatgagat cctgttcacg accatcgaca acgctaaggc ccagtcagtc tatgggtgga
     8941 atgtcgccac ggacacggtg cggccgatcg tgctttccaa tgggctgctc agcggaagcc
     9001 agctctactg ggatagcccc tgcacgctgt cagccgatac gctggtgtgc atcgcggccg
     9061 aggccgacca tccgccgcat ctcgaggcga ttgatgtagc cagtggtcat cggcggatct
     9121 tattcgcgcc gaataagggg ctggaggccg atatcttggc catggcgccg gcaaaattga
     9181 tccgttggaa ggacgcgcag ggtagggagt tcaccggcca gctcttcgag gcgcgcggcg
     9241 cacgtaccgg ccatccacca ccgttgttcg tgacgttcta tagctgttat ggctttctgc
     9301 gcggcggggt gggtaatgag tggccacttg ccaccctggc cgagggtggc atctcggcgc
     9361 tctgcataaa tgcgcttccg ggttttcaac tggataccgt ggcacattac gatcagggac
     9421 gcgcggccat agagagcgtt gtgacgcttc tgtccgccga ggggcgcatc gatcggacgc
     9481 gcgttggcat gggcgggctc agctatggaa gcgaggtgac gttgtggacg ctggcacatt
     9541 cagatgtggt gagtgctgcg tccgtcagcg gcacttcggt gacgccgact tattacctgt
     9601 tcaacagtct gcaggacgcc ttccgtccca cccttcggaa actgtggcag cttggcgcgc
     9661 cgaacgaaac acctaagcgg tggaaggaag tctcgcccgt gtatcaactc gataggatcc
     9721 gggcgccgat cctgttccag atgcccgagc gggaataccg gatgacccta gactatgcgc
     9781 tgcccctgat gcgcaggcat caggcggaca tttacgcatt tccggacgag acccatgtca
     9841 agttccagcc caagcacaag ttggctgtgt acgagcgtaa cgtcgactgg ttccgtttct
     9901 ggctgcaaga ctatgaagat cccagtccgg acagggccgg gcaataccgt atctggcgtg
     9961 gaatgaagaa ggccgcaaaa agtcgttttg gtgcgggcgc tcacgatgga tcgtgacctt
    10021 gttgacgcac ccagttctcg gccgcacaca gatcgaagag gcgaagaaac gacaggtccc
    10081 gaggtgcaag gtctttggcg aagaaatccg ccaatgcgga gcggtcgagc agatcatgtg
    10141 cacacaattg cccgccttct aggaattcgc ggatcttcaa cttgttgcgc atatagatgg
    10201 cagccatata gcccgtgtac gagcccttgc tgcgtcgatc gagaatggtt cgtggtagca
    10261 gatcggcgaa ggcttggcgg gcgacggtgc ggtttcgacc gccagcgatc cacatccagg
    10321 tcgggacgtt aaggcaggct tccatgacgg gttgagacag cagtggaaaa tgcgttgagt
    10381 gccccgcggc gcgaagtgtg gcgtccctga atagctgagt cccgaccaag tcatgaattc
    10441 tctcgcgatc gccgggtaat gcattcgggg gtgcttccat ccagggatga tgctccggca
    10501 ccgtggtcac ccaagctggg ttgagcaggg tgcggtcctc tttccaagcc gtatgtggcc
    10561 gacgcagcaa tttcttgaga gccaatcgac tggccttaaa gaccgtgcat tcgtgaaggg
    10621 ttgcaaggtc tccgatggcg gcgatacctg ccatggtgcc gcattccctg aacgcatcgg
    10681 cggcaggcgc agcggtcttc aggtagcaga aaacggtatc gccaccgtca cccgaaaagt
    10741 aaccatccac cccatatagg gtacctactg cctcccaggc ttcattggtg gcattctgaa
    10801 gaatcccgac tgcaggaacg acggacgagc gcggtacggg aaattcgaag cgggcattgt
    10861 tgaacccaac ctccaccggg aagagttcct gacccaacgc ctccgtcacg agacgggcgt
    10921 atgggcgctc gtccgttccg gccacgggca tgaccagtgt gcaaaagatg gctcgcggca
    10981 aagcgtggcg taggcaggca gcaactacgg aggaatccag cccgcccgac agctcaacca
    11041 aaaacctgtc gttactcgtg gataaagccc tgaccgcgct ggatacggca tctcggacat
    11101 cttcggcggc cacatgaggg tctgtgtgcc gaatgccttt ttccacgaag cgccacggcg
    11161 accaggcgga gcgaaccgaa acatcccttc cctggcaggc cagcatgttg cctggaagca
    11221 attccctgac gcgctgcagt gccgtacgcg ccgtcttgag gtagggaaag gtgaggccat
    11281 gtgcgatggc ctgccagttt acctcgctgc gatagagtcc caggtcgact gcaaggtcga
    11341 tgtccgaagt aatgaagcct tcgccatcgg cgagcgaata gacgcacggc acagcgccag
    11401 aagggtcgcg tagcagagtg gtcgccgagg ggttgtcgcg gtcgcaaaaa atggcgaggt
    11461 agttgcccca agtgttttgc agcaggcgac tggtgagttc gcgcaccgag ccatcgatat
    11521 ctagaggttg tgagatgagc tggccgtctt tggtaaaaac ctggccgatg agcagaccgt
    11581 gcccgtgtat tgtaagggta gggacatcaa tggaagcgaa gaccccgacc gacgctgatt
    11641 caagcttgca gatcattcct tcggcgcgca ggagtctgtt cagttgaagc gtgtagtccg
    11701 tgcttcgctt caatctttca ccgagaaaaa tgatatagcg gtatttcatc agaccatcct
    11761 gatgggggta tgcgcatggg cgtcggagag tgtttcattc aagacaatgt cgccggcctg
    11821 tacccagcaa tgcgcggcga agggatccgg cgtcacgccg aaaatgatat tcaccgatag
    11881 tccacgtcgc gaaaggaatc gaagtaggga caaggaatcc aggaggcaga tcggctcgat
    11941 gggcacatag cggcgcgccc gagcgaattg tccggttgcc tgaagcaggt tgtcttcagg
    12001 ggcggcgggt gtagcgatct cgtgcgcacc tgtttttctg tcgcggtatg cgcgggcttc
    12061 gtcgagattc gttttgagtg cgcgggtctt cagttggcga cgggtagacc agacgatcgc
    12121 catgacttcg aagacaatgg ccatatcgat ccgttgactc gcaatcgtgg cgggctgctc
    12181 gattgcgctg caagtcgggc gccggatgtt cgctattgcg gtacgacctt tcaggttcgg
    12241 tgcttcgacc aatatccgcg cggtcacgag gccatccact agcgtggggg cgatatcttc
    12301 atgtgcttgg aagcgtcgca tggcgttctc aagagcgcca gtcagcttga agtaccgatc
    12361 ttgcgcgacg tcgagaaaaa tcaggtgtcc gtcaacgtca cagtacgaga ggttttccct
    12421 gagccgatag tgcatcgtcc gtccctcgga atagggcgcg caccatgggt acgcgcccgg
    12481 ggttgctatt cctcggaaat gccgggaacg aacggaatgc cctgtccagt cccttcgttt
    12541 gatgggccag ggcccttcgt ctcaacactg gcgacgccga gctcgatgac atcgtcctgc
    12601 gcattgctgc ggatgttctc gttcgtgtcc atctcagtct cctgcggttg cgtcatggca
    12661 gtcccatgac gcgggcagcg taggaggcag agattttgat tttcaaatga ttattgcgct
    12721 gtcttccgat gattattccg ggagcgtgct ggtcgttccg ccatgccggc atcgacctcg
    12781 atgcttcttc gggcggcgcg ggctagctga agtaaccgca gcggtcgctg agcaaggcca
    12841 cgatgctagg aacgagctgc ttgcggcgct cgtgatagtc gcgcagcgcg gacttcaggg
    12901 ccggcatgtc gcgtgcctgc cagtgcaggt tcaactgcga aagctcttcg ccggtgtgct
    12961 cgaacaattc ctgtttggcc cgtcgtatcg gcgccagcct gtcgttggct cgcttcaccg
    13021 catggtgcag gggttcgtgc gcggtcgcgc gggcgatcgc atcgaacagc tgccaggtca
    13081 gtttcaccag gtcgccgtcg gcggttgcga gttccagctt tccggttttc tggaatgtcg
    13141 gcgcctcgcc gatatcgcat gccatcagca acagccgctc catccagtcg tagaggttgc
    13201 gcaaggcgac ttcgttgagt aacggcacgt gcagtccgtt gcgtgcatgg tcggtgacca
    13261 tgccttcgcc caccaggcgg tacagcgcga atcgaaccgg cgtgtggctg gtcttgtatt
    13321 cggaggcgag cgtggccgga tcgatccgtt gcccgggagc gtagcgtccc gcctgcaggg
    13381 cacgcctgac ctgtccgtac acgaatgcac tcttggaatc cacggcggga cctcccccgg
    13441 ccgcttttag cacgaaggtt attgcgatac aacgcaggat gtttcaggca gctgccgcgg
    13501 gcggtagccg caggtggaat ccacgcaggg gctggcggtt gcctcctcat cgcggggcga
    13561 tggtgtccag ccggctaatc gcactggttt ttcacacgac gcgtgggttt atccttcaga
    13621 tccagcttga cgatggtgcg gatgaggcgg gcctgaattt cgtcggaagg atcattggtg
    13681 cagttgtgtc ggtgcggccg acgtcatcgc aagttcttgc ctgattgacg ctggcgcgcg
    13741 gccgacgcga tgatggccgc agtcgtccgg gcgcctcgcg gcccgtgatg acgccatgga
    13801 agtcaggact ggggggtcac tgatgtcagg gaagaccaag agccgaagtg cgactgcctg
    13861 tccgatcaca acggacggat tcatcgtgcg cattggcagt ggactgcagg ctgtcgcgcg
    13921 gctggcactc gtttgccttt tggccagttt cagcgcgcac gctgcaggaa gcgactcgac
    13981 gtctatcgac tgcaacgcag accactgcgg actgctcgcc gatggcgctt atccgaatct
    14041 ggtcattggc cggctcgacc acgtggacac cgccgtggat atggcccggg cctttcattg
    14101 ggctgagaaa caagagtcag agtgccgttt tcagggtggc cgtttgaaag tcgactctga
    14161 ccccgatttt taaggccggc gtcgaccggc agaaaccgac ccaaagctga cagttgaacg
    14221 tctatctagt cgcgctctta ggcttgaggg gcacgtgcga cccggggtac ttttgaagtg
    14281 tctgcttgac gggggagctt acgaccagat ctggtttaat ttcctacagg ccgctgcaga
    14341 cgtcaccctg atttgctata acgcctgtca cgggatgagc tttcgatggc aaaggacgtt
    14401 ccgcacacac agcaatccac gtcacagggg aatcaaatgg acttcgttcg gcgcgtgatg
    14461 gaaagcacag caacctcggg gggcgctatg aacttcgctg gaaatgttgt cggcgctgcg
    14521 cgtggcattt ataagcatac cttgccacag ccaaccgagt tgcagagaga ggctcaagat
    14581 ttttcaatag gaagcatagc gcttaggaat atcgtgctaa gacttagcgt gtggcttctg
    14641 atcactttaa gcgtgctcag cggctcggcg ctcgcagcta gtggtccaac accatcttct
    14701 ccaatttaca cctgcggatc ggggatttgc gccaatgcgt cgcccccata cggaaccatt
    14761 tgcccgtcgc agggaacgat tagcgagtac cggtcgtgtt ccgagacgta ctacaacagt
    14821 acgctgaggc aatacttcgg gccactgaca tatctctaca caactgtcta tcctccaggt
    14881 tcaggcgggt ttcaaatatg gtggagttcg ccggggaacg gtaactatac aagtggcggc
    14941 ggttttaagg cccccggcca agatgttcct gcggtagaac gcaatctggg atttaaggga
    15001 tgcagctctt gcggcggggc aatgctgggc aatccagtaa acatatccac gggaaacaag
    15061 ttcgaggacg agacggactt cgaaggcttt ggctcttttc ctttaacttt tcatcgctat
    15121 tacaacagcg ctagtttcgg tggtgatggc accctgggcg ttcagtggac gcatacattt
    15181 agtcgctctc tagtgctgca aagttccaca gaggcgaagc tgtttcgtga caatggggaa
    15241 attcgctact ttaataaatg tggaagtctg tggtgtgcaa cgccagatga agtgggttct
    15301 ctgctcgagt tcactgcggg caatggggct atcactggtt ggcaatacac cgatgaaaac
    15361 aaaattgtcg aggtatataa ctctgacggc acactccgct cagaaacaaa ccgagacggc
    15421 ctaagccttg tattggccta cgatgccaca gatcggctca gcaccgtcac cgattcgttc
    15481 ggtcgtcaac tcgcgctgac ctataacagt accaaccaag tagcacagct caaagcaccg
    15541 gatggtggca taagcactta tgcttacgat gcctctggta acttaagttc agtcacccat
    15601 ccaggcaaca ccacacggac gtatttctac aatgagtccg gcaatgttgg gacaggtgca
    15661 ggccccaatc ttctcaccgg aatacaggat gagtcggggc aacgctttgc cacctttcaa
    15721 tatgacggcc aatccagagc cactatcagc gaacacgcca acggtgcagg cgctatccag
    15781 ctcacctata acgctgacgg cagcacaacg gttctcaatg catcgggcga ttccaaagcc
    15841 tatgcattcc aaacagttca gaacgtcaac catacggcca cggtcaacgg ttctgcttgc
    15901 gcagactgcg gcatcaattc gagatatgcc tacaattctg ccggcgatct caccagcacg
    15961 gtcgatttca acggcaatac cacgcactac tccattgatg ctgcacatct tgaagagagt
    16021 cgcatagagg cgtccgggac gcctatgcaa cgcacgatca acacggcatg gaacaccgct
    16081 ctgcgtgtac cactcacacg catcgtgacc gatgccaata gtaacgtggt tagtagtatc
    16141 agctgggtct acaacaccgt tggccagcca ctggcgcgtt gcgagatcga tccggcccag
    16201 gccagtagct acgcctgcgc caccaccggc acgccgccgg ccggtgtccg ccgctggacc
    16261 tacagctact gcacggccgt cgataccacc cagtgcccga tcgtgggctt gctacttgcc
    16321 gtggacggtc cgcgcaccga ggtggccgac gtcaccacct atacgtatta cctgaccgac
    16381 agcaccaccg tgcatcatgg cgacctgcag tcggtgaccg atgctctggg ccacaccacc
    16441 agctatctga cgtatgacgg tgccggccgc gtcaccagcc tgcaggacgc caacggcgtg
    16501 gtcactaacc tgacttatac gcctcgtggt tggctcgcct cgcgcagcgt cggcggtgcc
    16561 accacgaccc tggcctacac tgcgtatggt gcggtggcct cgatcacgga tccggacggc
    16621 gtcacgaccc attataccta cgacgccgcc caccgcctga ccgacatcac cgatgcgcag
    16681 ggcaacgtcg tccattacac gctggataac gccggcaaca agactggcga gcagatccgt
    16741 actgcttccg gcactgtcgt gcacagcctg tcgcgcacct tcaacgccct gggccagctc
    16801 acggcagtgg tcgatggcct gaaccacatc gtcttcaacg ccggcaccag tggcagctac
    16861 gatggcaatg gcaatctggt gcagtccacg gacgcgctgg gcatccagcg tgtgcaaggc
    16921 tttgatgccc tcaaccggct gcaaagcacg atcgccaact acaacggtac cgacccggca
    16981 accaagaaca cccagagcgt gttcgcctac gatgcccgcg acaacttgga gggcgtcggt
    17041 gatccggacg gcctcaacac cacctatgac tacgatggtc tgggcaaccg cacggcgctg
    17101 catagcccgg acacgggcac cagcagcgat acctacgatg ccgccggcaa tcgcctgatg
    17161 cacatcgacg caaagggcat cgtcagcacg tcgacctacg acgcgaacaa tcgcctgatc
    17221 agcaccggct acgccgacac cactctcaac gtcagctacg cctacgacga ggccaatgcg
    17281 gtgaccggct gcagtgcatc ccgtccgatc ggacgactga cgcgcgtggt ggaggccggc
    17341 gtcactaccg tgttctgtta tgacggtcgg ggcaatgtca tccagaagcg gcaggtgaca
    17401 gcgagccaga cggacaccac gttctatacg tataccgcgg gagatcgcct cagcagcgtg
    17461 agtgcacctg accagacggc gatcagctac gcgtatgaca gcgacggccg ggtcagcagc
    17521 gtgcaggtgg tccctgcagg gacgagcacg gcgccaccga ccgtggtcag caacatcagc
    17581 tacctgccgt ttgggccgat cagcagctac acgctgggca atggccaggt cgtgacgcgc
    17641 gcatacgacg cgaactaccg gttgaccgac ctgaccagcc aggcgctcaa cctgcacttc
    17701 aatcgtgatg cgatgggcaa catcgtcgcc ttgggcaatg ccccgggggc caatcctgcc
    17761 acggaggcct atagctacga tccgctgtat cgccttaccg gtatcaccga caacggtgct
    17821 gcgctggaga gctacaccta tagccagacc ggcgatcgac ggagcaagac ggcatcgggc
    17881 ctggccaccg gtgtatacct ctacaccagc ggcacccacc agctcgccag catcaatggt
    17941 atctcgcgtg ccaacgacgc caacggcaac accaccggca gcgtgatcgg cggcaatacc
    18001 tacggtttcg gctacaacgg gcgcaaccgc ctgacggtgg cgcaactcaa tggcgcgacc
    18061 gtaggcacct acacctacaa cgcgatgggg cagcgcatcg gcaaggtggc cacgttcccg
    18121 caggcgacga ccgaacgtta cgcttacaac gaagcaggcc agctgatcgg cgaatacggg
    18181 acgagcagca ccactctgtc aaagggcaac ggaaaacacc aaggcaagca ccaccaacat
    18241 gcaggcacgg tggtcacaaa caaccgggat tacgtgtggc tgggcgacat cccgttggcg
    18301 gtgatcgaca acaccatcaa cggcagcgtt accaccagcg tggtcaacta cgtgcacgtc
    18361 gatggcctgg gcacgccgcg ggccgtcact gacggcgccg gcacgatgat ctggtcgtgg
    18421 ccctatgtag gcaacccgtt cggacagcaa gcgccgacgt cgacgacagg ctatgtactc
    18481 aatctgcgct atccaggcca atactttgat tccgaacgcg gccttgcgta caacgtcaat
    18541 cgagactacg aggcggcgac tgggcgctac attcaaagcg accccatcgg gcttgccggc
    18601 ggcctcgcgt catattccta cgttgactca tcccctcttc aagacatcga tcttttgggg
    18661 ctcaagaaag tcatcctctt tggtgaaagg gattccgtgt tcctgcagcg cgcacatgag
    18721 tacaaagatg atcccaacgc atgtctagtc tattcacacg gaagtccgag cttcatctat
    18781 gacaccagag gggacacaac aaagcgtatg gatgatcctc agcagatcgt gaatctacta
    18841 aagaccgaag gttgcactag caatatgccg gtgatcatct atgcctgccg aacaggcatg
    18901 ggcgacaact ccatcgcgga agacatcagc aagactgggg catttccgag tgtcactgca
    18961 ccaacgagct atgtctggta caaccaagat ccgacgtcca cagggccttc gcttattttt
    19021 gggaagaacg ccaacagcac aatggacacc gacagcccgg gaacaatgag gacatttcca
    19081 tgacacggaa aaatcaaacc atttctcgag tgttggctac cctcctgctc agctctattg
    19141 tgctcatcgg atgcgcagcc cacgcgactc aggaggcggc ggttccaacg ccaggcgagc
    19201 gcttctcaat tagtcagtct gagcttccga aggtaaaaga ccaggcagcg cacggtgacg
    19261 tgagtgccat caataagctt gtcgactatt acatgctcta tctgggagac gaagatcagg
    19321 gcattttgtg gcttgagcgc cttggagaca ctggcgacac tgaagcaagg aagaatgtct
    19381 tgaccttcta ccaacggcat ccgtctgcaa acaacaccaa gcatttagag cttctgaagg
    19441 cgcgctgggg tatgtaaaga caacaggact tctagcccag caagattttc ggcgccgccc
    19501 atggaggctt gcagctgcga gtccaatatc cgacttccgg ggcagtactg ccgccttcag
    19561 gaacgagtat ggccggaata gtctgctggt gccttttacg caagcgcggg ccacgagaaa
    19621 gtaccgtgct cacgatggca ttgtggtgac cgatagattc cgcaaaaaaa atcgtgcctt
    19681 tcgccgcata aatcaataat tgagagtatg cacgtctatt tttcgcaata agtttcgtcg
    19741 cgcgaagggt cgtcacggtt cacatgacgt gcgattatga cgaggtcgtt cgtgacggga
    19801 gtcacaatga caaatgccgg ccttgccgga tccgcgctgc ctagaggaat gcaaccgggt
    19861 tgtatggcgt ccgacggcaa tcggtgatgg atccaggacg gagttcatca atcaggggga
    19921 aatcatgttc aagaaactat tgtcggcatt cgtgctgacg ggcgtactgg tcgtgtcggg
    19981 ttgtgcaagc gtacccatgg ccgggcagag tgcggatatg caggcaaagt cgttcacgcc
    20041 gtccgcggac aaggcgacgg tctatatcta tcgcaacgag aattttggcg cggcgatcaa
    20101 gatgccggtg ctgatcgaca acgcggcggt cggcgacacg gctgccaaga cctacatcga
    20161 gaagcagctt ccggcgggga cgcataccat cacatccaag accgagaagg attcatcggt
    20221 caccatcgac atgttggccg ggcagatcta ctacgtctgg caggaagtaa agatgggcat
    20281 gtgggctgcc cgctcggcac tgcatgtcgt cgatgcgaaa aagggccagg ccggtgtacg
    20341 cgagtccaag ttgatccagt aatgacggaa gacaaacgta tcgtgtgact gggcattcgg
    20401 cactagcgat tgtccaccgc gaacgtaacg atggggtcag gttcacttcc cagccatgga
    20461 ttaggtgaac ctgaccccgt tttgaccgta gatgcatgct caccatgctc ttcggcatcg
    20521 atttcatcat tgtcgcgagc attgccgggc gctggcggca tgcgcagcga gttcacttcc
    20581 aaacacaaaa gcacggcaat aaggggccgg agtggaatgg cccagttacg caatgaacaa
    20641 ctcaaagggg gagtttgatg accaggccgt ttgttatatg ggtgactgtg gtgttgtcgg
    20701 tgctgctggg tgtgtcggct gcctttggac ttctgaaggt catcctgcag gtgccaatgg
    20761 ggttggggcc gaatagtgcc atcccggttt ggcgcgtgct gctcatggtc gctatccaag
    20821 ccgtcgcgac tatgttcctg gctgcggttg tttatgcggc gtttgctcgc ccacgttggg
    20881 gccgggccgt ttgtgccgtg tttgcggtcc tgctcgcact gatggtgctt tatgccggct
    20941 tccatcccga cccgcatccc ctgttcgcga tcaagtcagg cgctgaagaa gctggcgctg
    21001 ttgtgggtcg attgatgatg tgcgtgttgt tcggcgtgta tgcctacaag atggtcatcg
    21061 gaacgaaggt gcgcgcctat ttcttgtcga ccgaaggtcg aaagtagagc ataggtaatc
    21121 agctggaagc ggggaagggc gctccttgtc gtctgtagag acgcatgcgc cctgattttt
    21181 cttgcgccgc aattcaatgg tcgacgactg gagcggcatg atgcctgatt cgaaaacatg
    21241 ggtatggctc tccatggctg tgctgttagc agcctgtggg catcctggcg aaccggccta
    21301 tccgcccggg cccgatgtcc agttccatct cggtactttc gaggcgcggt cgggctaccg
    21361 attggcagag ttaccttcgg gtgtgcacgc catccatcta gatcccaaca tcgttgtcgg
    21421 cacccgcgat atcgcctatg tgcgcgatgg tggatgcctg gatggagcat gttcggtcga
    21481 ttttcggttc agtccggaag gcggaaaacg catgttgcga gtgtcggagg cagcaatcgg
    21541 caggcagatg gctatcgtgg tggacgggaa agtggtttcg gtggccgaca tcagtggccc
    21601 gattagagat ggactcagac tgtcaacgac gtcagaagaa gagtcacagg cgttgatcag
    21661 gcagatcgct gttgttccgc aacacgtgga ttgaccaaaa aaccaaaact ggagtctggg
    21721 cactttcgag ccggttcggt ggaaagtcgg ctccgatcga tgacctcggt tcgatctcgt
    21781 acccaattac tcgacggccg cgtcgtgccg cgccgcgagg tgcatcgttc accgtgccag
    21841 cagataagcg cgcagtgcca ggtcaccggc ggcgcctgga gcgttcagca gttgatcgag
    21901 agtggccagt tgccgattgc aattggccga ccaatggact tcatcgacca gttcgccctg
    21961 cgaaacccag cgctcctcct gatgcttgtg caaggcgtcg gtcaggctgg cgcgccatgc
    22021 cggtgacggc aattggacgg tgtcgttgcc ggagaacaag gcgagatacc cagggccgac
    22081 gatatccttg aatgcgccgg cgtgggggcc gaggctgatg gcgatgccgc tggcgtaacg
    22141 accgcaagca gatgtggaaa gttgttgacg caacatcgtc aaggtctgct gatggctcag
    22201 cgcataacgg cgcacgtcct gcgccgaggc gacttcgagc tggtgcgcgc gtgcggcgtc
    22261 aagggcatgc cagaagttgt cgttgcgccg cgccgcggcg gcgctgcgcg gatttgacgg
    22321 tacggccaag tcacccagca cccaggtccg gtagatcgcc ggctgcacca cggcgattcg
    22381 gtcgaacgtt tgcgccagcg tgcggccatg cgggtcgtgg cgcagtgcct gcaga
//
