LOCUS       NZ_CP030862            21333 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces globosus strain LZH-48 chromosome, complete genome.
ACCESSION   NZ_CP030862
VERSION     NZ_CP030862.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces globosus
  ORGANISM  Streptomyces globosus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6863360)
  AUTHORS   Ran,K., Li,Z., Wei,S. and Dong,R.
  TITLE     Draft genome Sequence of streptomyces globosus LZH-48
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6863360)
  AUTHORS   Ran,K., Li,Z., Wei,S. and Dong,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2018) Institute of Biophysics, Dezhou University,
            566 DaXuexi RD, Dezhou, Shandong 253023, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Portal v. version 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003325375.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:22:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,671
            CDSs (total)                      :: 6,576
            Genes (coding)                    :: 6,458
            CDSs (with protein)               :: 6,458
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 41 of 118
            Pseudo Genes (incomplete)         :: 101 of 118
            Pseudo Genes (internal stop)      :: 11 of 118
            Pseudo Genes (multiple problems)  :: 32 of 118
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:39:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6802450
            Orig. end                         :: 6823783
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030862.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21333
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="triceptide"
                     /region_number="28"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     triceptide_precursor) or triceptide_rSAM)"
                     /tool="antismash"
     cand_cluster    1..21333
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /kind="single"
                     /product="triceptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21333
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11333](+)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11333
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
     misc_feature    complement(490..506)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            1119..1949
                     /locus_tag="C0216_RS30290"
                     /old_locus_tag="C0216_30270"
     CDS             1119..1949
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155179.1"
                     /locus_tag="C0216_RS30290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30270"
                     /product="hypothetical protein"
                     /protein_id="WP_114058302.1"
                     /transl_table=11
                     /translation="MHMNSAPHLLAEDRPEFDRLLDEALRTAHERPELAALGERLSAGQ
                     LRAMAVGASALLTAAAAAEYDRFVQVRDARRTEIRSTPRSGGSGDAPEESGAGLSAVVA
                     VLAPVLAAAAMLIFLLVGYVLKAIEPEPALADTLLTAGWFFGALTAVTLLGAVVGLLVT
                     ALRNRATEVVAGDEDRAAPDEVSLAREAWRQALLERGILPFLRDALAAPGAGPEHAAPG
                     TPTAGRIPDLGYTRPDFSSPRSPAQGARPGYTAPDFSGPEFGSPGFGSASREPL"
     gene            complement(1965..2789)
                     /locus_tag="C0216_RS33655"
                     /old_locus_tag="C0216_30275"
     CDS             complement(1965..2789)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS33655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C0216_30275"
                     /product="hypothetical protein"
                     /protein_id="WP_162793319.1"
                     /transl_table=11
                     /translation="MSSEDRTRSSLGPLPRRAGWLAGGTFASLALVMGAAVAAPAAVGA
                     PQPSGAVVSDTGDHCDLATANKATDPPAVSAQPAGGDKCKVGPTGPRGPKGKTGATGPT
                     GPTGPTGPAGTGATGATGATGATGPTGATGPQGASGQCFDVDAVRPAAAREVKAVLADT
                     VTYAGIRDLTPAPTPWRWYDLTDTGETYPTDACAVSVSSQANIVNIEVLTTGGEIYETS
                     CTINPGTPDALTCNEVWTAADPQPAAGANGLARFANKSLSPQDMNLRPADVN"
     gene            3026..4162
                     /locus_tag="C0216_RS30300"
                     /old_locus_tag="C0216_30280"
     CDS             3026..4162
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135590.1"
                     /locus_tag="C0216_RS30300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30280"
                     /product="glycosyltransferase"
                     /protein_id="WP_246042749.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.1e-12,
                     bitscore: 45.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPTICLCMIVKNESAVIERCLDSVRDLVDTWVISDTGSTDGTQD
                     LIRKALHGIPGELHEEPWTDFGHNRSLNIAHARGKADYLLLLDADLVLRRNGPLPELTA
                     QSYMLRHEGPTEYRIKRLVRGDLPWRYEGATHEYLTCDRPGEYEDRPGVQENLDALSIV
                     DHADGGSRHDKFERDARLLGAELERDPSNTRAVFYLAQTMRDMGETAEAIRLYEQRAAM
                     GGWEEEVYYALLQSGVLRAESGDWPGAMDALTRAWETRPTRLEACYELAARLRVQGRHH
                     AAHAVTTAVLDRPAPPDLLFVHPWVYRWGLLFEHSITAYWVGDMDASLRACDRLLALPD
                     LPEVYRRQTEANRGFALAGGGSPDPVSRETSPRQPTGV"
     gene            complement(4280..4414)
                     /locus_tag="C0216_RS35160"
     CDS             complement(4280..4414)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS35160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_281277964.1"
                     /transl_table=11
                     /translation="MKISQDIRREHGGDLKAEEIQAGMAEKSAEFAASGNRVYLPLAD"
     gene            4488..6047
                     /locus_tag="C0216_RS30305"
                     /old_locus_tag="C0216_30285"
     CDS             4488..6047
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004948338.1"
                     /locus_tag="C0216_RS30305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30285"
                     /product="recombinase family protein"
                     /protein_id="WP_246042750.1"
                     /transl_table=11
                     /translation="MATRDEVVSKLRGVPAEVPSVPEVMAMLAANPKMRCVVCYARISF
                     DGRAKDAHGIEDQHRELGEKANGFEWLVVYRYTDNDKSASKEEVVRDDFEQMLTDLTAG
                     RTPEGYPIHGVMAINDDRLYRRPGDWERYLRAFTAHPDRVYYDSNGHQDLYAEGFEVKG
                     LVGVAMSLAETRKKQRRSRTSHRNRAIRGQSVSAWRPFGWDDDKVSLRPAEADAIRKAV
                     KDVLAGASLSEVTAQWKEAGFTTSRGNAFQYATVKQVLLNARLCGYREIVGELVRDEDG
                     QPVVGEWEAIVTPKEWFAVVATIRERGRGKGQSPGGVVHKYLLTGVLRCGAVREDGTAC
                     NNKMTGVKANDWVSYSHGYLCKKTVDGGCNKTYKRGDETDKHVSTLVRAKLKRDAAAAA
                     KDVPEWTRDEELESAVARRRALEQRWQTGQIDDETFFRNLSPMDQLVKELRADQAKHLA
                     MVAAAEAATADIDTEWEAKTLTQKREMIQNALLAVIAEPGGKGRKPFDVTQLRPVWRSA
                     SA"
     gene            complement(6177..>7385)
                     /locus_tag="C0216_RS30310"
                     /old_locus_tag="C0216_30290"
                     /pseudo=""
     CDS             complement(6177..>7385)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014178419.1"
                     /locus_tag="C0216_RS30310"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30290"
                     /product="zinc finger-like domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="ACSGGHAADTFHLVRAGLCGGKNVPETVRTHPRVFLTLTAPSFGP
                     VHNRPTTNTGKPYPCRCGTWHPEGAPEVGTPLDPKTYDYTGAVLWNAHAGALWARFTLN
                     LRRALAAHLHMTQKAMKEVLRVSFAKVAEYQQRGLVHFHAVVRFDGPDGHTSAPPAFAT
                     VAALNEAIGTAVEATALAVVSDTVGDHEIRWGRKFDVREITALGDGELTDAAVAGYVAK
                     YATKSAEDSGTVHRTMVCRTCSGRGTVGGTIRDLCPDCHGTRQAEPIKNLRAQSHVRQM
                     IRTAWDLGGLSEFADLKLCKWAHMLGFRGHFSTKSRAYFTTLGALRDVRRAWRTAQAEA
                     ARARSGHPAPGPDTVLVTESSWAYLASGYRPGEELLANQTRHEINQARADKERAKTEGE
                     VWA"
     misc_feature    complement(7635..7653)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.28"
                     /tool="antismash"
     gene            7742..8977
                     /locus_tag="C0216_RS30315"
                     /old_locus_tag="C0216_30295"
     CDS             7742..8977
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008739359.1"
                     /locus_tag="C0216_RS30315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30295"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_114058303.1"
                     /transl_table=11
                     /translation="MSGYIEEQERIGQRVRRQRLSVGMTQADLAAALGRTQGWVSKLEK
                     GRIELDRAGLINAVAAALHCHPNTLIERPYTGGGAETKWQVSAASILRELRRYDLTPVF
                     DGTPRPSEVLWQDMKRLLRLRDAAANGAVLAELPDMLREARALAEVSTGHEREEAFAIY
                     AVACKFAHTAAHALGHPELVAMACERATWSAQLSGDPVMPAMALWMRMWDTWASADWDD
                     ALALGDKALAGIETEYEAGDPLALRMWGALHLRAAISCARAGNPAGSDERIALARTAGE
                     RVNSYVGPEIHDRHSVTFSLGNVIIHSVSAALEMSDQTKALRLNREADPAHISVLPNSR
                     LGHHHMDLARAWLWDGNRDQALTELETAERIAPQLVRNHPVARATLRKIVYAERVATRQ
                     RLRGMTGRFSLD"
     gene            9036..9452
                     /locus_tag="C0216_RS30320"
                     /old_locus_tag="C0216_30300"
     CDS             9036..9452
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS30320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C0216_30300"
                     /product="hypothetical protein"
                     /protein_id="WP_162793320.1"
                     /transl_table=11
                     /translation="MTSTRRTDHDRVRRQADDTDPRWPLRGDLAYDTATSRTGVVIDVP
                     NDTGTTVYRLCPEGGGVAGWSASLDTLVPAEDAAPQPIPRRPPANEPQGQPEYAPWDAS
                     SSPDPSPGLRARAERGMERFSKSADEDDQAGSTA"
     misc_feature    9044..9064
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.29"
                     /tool="antismash"
     gene            9449..9658
                     /locus_tag="C0216_RS30325"
                     /old_locus_tag="C0216_30305"
     CDS             9449..9658
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008739357.1"
                     /locus_tag="C0216_RS30325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30305"
                     /product="hypothetical protein"
                     /protein_id="WP_114058305.1"
                     /transl_table=11
                     /translation="MSRLPRWLHEGARVLDPAEDREGIVQFIGEWVDPTTRRAIPRAIF
                     LRPEGGGREWVVADHQALREADPR"
     gene            9655..9828
                     /locus_tag="C0216_RS33660"
     CDS             9655..9828
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS33660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162793321.1"
                     /transl_table=11
                     /translation="MNARPGELPPPGWGMIASLLLIGLAGPAIVLSGQVLNLDQSASTP
                     PPATVPDVEPPS"
     misc_feature    9676..9678
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..11119
                     /gene="amcB"
                     /locus_tag="C0216_RS30330"
                     /old_locus_tag="C0216_30310"
     CDS             10001..11119
                     /codon_start=1
                     /gene="amcB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_rSAM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041718.1"
                     /locus_tag="C0216_RS30330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30310"
                     /product="cyclophane-forming radical SAM peptide maturase
                     AmcB"
                     /protein_id="WP_114058306.1"
                     /sec_met_domain="PTHR43273 (E-value: 2.7e-46, bitscore:
                     156.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 9.3e-12, bitscore: 44.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="triceptide_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSALRLATVPRSVIMQPTTQCLPMDCTYCYLPFRKMKNLMPVAV
                     AEAVATSVNPWAADDPAFEVVWHGGEPLATGREHLTALMAPFRGVKHSVQTNAALIDDA
                     WCAFLLEHDVHVGVSIDGPADMNTHRITLAGHPGFRVTMRGIERLRHHGIPYSAIAVVS
                     DPDPADAARFYEFFAELGVTTLGVNVEEEEGVNTGSKDADPVRASEFWAALTDAWHGNP
                     VIRLREVQRVLNFAGAVLQGHETAPMPASSPWDPLPTVAHDGGVVMLSPELAGFTDPRF
                     GDFTTGNVLKDDLDVLVAEAEERTPWITEFWDGVDACRATCPTFAFCGGAHPANRYFEH
                     GGRMDGTRTSYCTTSKIALLEGVTRHVRTHRP"
     misc_feature    10013..10015
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11097..11333
                     /gene="amcA"
                     /locus_tag="C0216_RS30335"
                     /old_locus_tag="C0216_30315"
     CDS             11097..11333
                     /codon_start=1
                     /gene="amcA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_precursor"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041721.1"
                     /locus_tag="C0216_RS30335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30315"
                     /product="multiple cyclophane-containing RiPP AmcA"
                     /protein_id="WP_114058307.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAHTAPDATTLVMDSAPGFTSLLEAAGTAAIARWGNTWSNADFE
                     NYLSATTFDNRPTWDNPTPVFDNRPTWDNWKNK"
     gene            11408..12082
                     /locus_tag="C0216_RS30340"
                     /old_locus_tag="C0216_30320"
     CDS             11408..12082
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024986.4"
                     /locus_tag="C0216_RS30340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30320"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_114058308.1"
                     /transl_table=11
                     /translation="MATRTFGHVTVTTPDLDEPGLYLSTVDTLDSPRGALQDFTFGDAD
                     LRALGLADTQLVTGRITGLRSKRVEFEALNLHGVEITGSDLGAVRWNESKLTRTLLRDC
                     KLMGAALDGLVLDDVLFEGCKFDYATFEKVRATGPVAFAGCTFTEATFTDCDLSDVVFS
                     ECTFRLTEFGTGRYRDTDLRGNDLSTIRGVSNLSKIRIGHVQQSDIAQALVNELDMTLG
                     DD"
     gene            12096..12812
                     /locus_tag="C0216_RS30345"
                     /old_locus_tag="C0216_30325"
     CDS             12096..12812
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS30345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C0216_30325"
                     /product="hypothetical protein"
                     /protein_id="WP_114058309.1"
                     /transl_table=11
                     /translation="MPLHVAFTDRGGLRGRCDVAAVRTVIGDPAFEDGAVVPSGLWQPL
                     SESAAQALNAPPWTPPSTLVEIVRPPAPNGGKLEDLAQQIGDEQAQYLGQALAKPDMIT
                     TTENYQDGRLIGLHLDNWDKLNYGQKTTGRRRLALNLGPGTRYILLGALDAQAVCRAVH
                     PEDYAYRCPSTDDYRAHVAAGHPIRCIRIRLAPGEGYIAPTEYLLHDGSTDNQDQPSAM
                     AFWLGRWQRGTLPSLV"
     misc_feature    12102..12104
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13047..14840)
                     /gene="thiC"
                     /locus_tag="C0216_RS30350"
                     /old_locus_tag="C0216_30330"
     CDS             complement(13047..14840)
                     /EC_number="4.1.99.17"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890647.1"
                     /locus_tag="C0216_RS30350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30330"
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="WP_114058310.1"
                     /transl_table=11
                     /translation="MTIQDARTPAAGRDADGQTERQPGWHKGYVAGSRPDIRVPVRQVH
                     LTNGKDVTLYDTSGPYTDPQIETDVRRGLPPLRENWIIGRGDTEEYAGRPVRPEDDGIK
                     HTSPRGGLKNLDAVFPGRPRLPRRGRGGQAVTQLAYARRGEVTPEMEYVAIRENVSPEV
                     VREEIAAGRAVLPANVNHPEIEPMIIGKRFLVKVNANIGNSAVTSSIEEEVEKMTWATR
                     WGADTVMDLSTGRNIHTTREWVLRNSPVPIGTVPLYQALEKVDGKAEELTWEIYKDTVI
                     EQAEQGVDYMTVHAGVLLPYVPLTARRKTGIVSRGGSIMAAWCLAHHKENFLYTNFEEL
                     CEILAAYDVTYSLGDGLRPGSIADANDAAQFAELKTLGELNTIAKRHNVQTMIEGPGHV
                     PMHKIKENIDLQQEICEEAPFYTLGPLTTDVAPAYDHITSGIGAAMIAWWGTAMLCYVT
                     PKEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPGAQEWDDALSDARFEFRWEDQFNLA
                     LDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMKISRSITEQFGGEADVTPEEVEAG
                     MLEKSKEFAASGNRVYLPLAD"
     regulatory      complement(14835..14977)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            15017..16462
                     /locus_tag="C0216_RS30355"
                     /old_locus_tag="C0216_30335"
     CDS             15017..16462
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741691.1"
                     /locus_tag="C0216_RS30355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30335"
                     /product="YibE/F family protein"
                     /protein_id="WP_246042751.1"
                     /transl_table=11
                     /translation="MGPLISCDDQPVTPSTMPSGEPTDPHEPPPSDGRAPNGRGRSPEP
                     GHSHGHGHVHSHAHGPAAPVSKHLRKVIAAVLIPFAAAVFVGMAVLWPNGAPAHERSGV
                     GFDRQTEQARVVAVETVDCKSVNASQVPPTGDTSTPSGREAVAGQNGSCKKATVEVGTG
                     PDKGRTFFEIVQPGAPRQLAEGQEVVVAYAPDAPRDLQYSVIDVNRKLPLAVLAGLFAL
                     VVVLVGRMRGLFALISLAISFTVLTLFILPAILQGANPLLVAVIGASAIMLVALYMCHG
                     LTARTSVAVLGTLVSLLLIGLLGSVFIDWAFLSGNTDDNTGLIHGLYPEIDMSGLLLAG
                     VIIGSLGVLDDVTVTQTSAVWELHQADPSMGPRAVYLAAIRIGRDHIASVVNTLVLAYA
                     GAALPLLLLFSIANSSMGSVANSELVAEEIVRTLVGSIGLVASVPVTTALAALVVSADR
                     PGSQAAGGAPAAGRGGRGRRRKR"
     gene            complement(16476..16925)
                     /locus_tag="C0216_RS30360"
                     /old_locus_tag="C0216_30340"
     CDS             complement(16476..16925)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019992482.1"
                     /locus_tag="C0216_RS30360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30340"
                     /product="SsgA family sporulation/cell division regulator"
                     /protein_id="WP_114058312.1"
                     /transl_table=11
                     /translation="MRESVQAEVMMSFLVSEELSFRIPVELRYDAGDPYAVRLTFHLPG
                     DAPVTWAFGRELLLDGINKPCGEGDVHVAPTSPDELSDVHIRLQVGSDRALFRAGAAPL
                     VAFLDRTDRIVPLGQERSLGDFEGSLEEALDRILSEARQNEQNAG"
     misc_feature    17018..17032
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.4"
                     /tool="antismash"
     gene            complement(17023..17769)
                     /locus_tag="C0216_RS30365"
                     /old_locus_tag="C0216_30345"
     CDS             complement(17023..17769)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741689.1"
                     /locus_tag="C0216_RS30365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30345"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_246042752.1"
                     /transl_table=11
                     /translation="MSTLIGSVQRALRLLEAAGSHSGGAPAKQLAREAGLPLPTAYHLL
                     RTLTYEGYLRREGGVFVLGAAAGRLAGGGVQQKRRSMILDSLAHFRDAVGAPVYFAVFR
                     DGEIEVVGVSDTPSDPAVEEWADFRATGHAHAIGQCLLAQLDEETRRDYYDRHPVEAIT
                     PYTVRDQRALEQRIGSLGRMQPVTEHQEYALGTVCAAIPITAGDTAATMAISLPLHQAE
                     KLPCVVARLRSEVGALLSTLSFSISI"
     gene            complement(18066..18293)
                     /locus_tag="C0216_RS30370"
                     /old_locus_tag="C0216_30350"
     CDS             complement(18066..18293)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265271.1"
                     /locus_tag="C0216_RS30370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30350"
                     /product="DUF5326 family protein"
                     /protein_id="WP_114058314.1"
                     /transl_table=11
                     /translation="MDGIRETFAGMPWWVKWVAIPLLVLFVFGGVITSILGALIGFAFK
                     LLLFVALVGGLVFLVKKFGGSSTKSSSRDW"
     gene            complement(18493..18810)
                     /locus_tag="C0216_RS30375"
                     /old_locus_tag="C0216_30355"
     CDS             complement(18493..18810)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005315079.1"
                     /locus_tag="C0216_RS30375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30355"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_114058315.1"
                     /transl_table=11
                     /translation="MKAFRLDELEAERLANDGAYLQFLREPNMSVGLYALDAGQSDPQQ
                     PHRQDEVYFVVSGRASITVGEETTTVARGSVVYVPAGVPHKFHHISEDLKVLVVFSPPE
                     A"
     gene            18898..19281
                     /locus_tag="C0216_RS30380"
                     /old_locus_tag="C0216_30360"
     CDS             18898..19281
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003975010.1"
                     /locus_tag="C0216_RS30380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30360"
                     /product="phage holin family protein"
                     /protein_id="WP_114058316.1"
                     /transl_table=11
                     /translation="MTNFVVKTLANAAALAVAIWLVSGITLDDHSSSLGHRTLTLVLVA
                     LVFGLVNLIVKPVVKLLSLPLFVLTLGLFTLVVNALMLLLTSWLAKQLDLSFHVDGFWS
                     ALLGGLIISVVSWAVNLALPDKD"
     gene            19321..20496
                     /locus_tag="C0216_RS30385"
                     /old_locus_tag="C0216_30365"
     CDS             19321..20496
                     /EC_number="4.4.1.1"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388927.1"
                     /locus_tag="C0216_RS30385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_30365"
                     /product="cystathionine gamma-lyase"
                     /protein_id="WP_114058317.1"
                     /transl_table=11
                     /translation="MNGNDRTGGRASAPTAAGEGTRAVRAGLPEPVKNEPPLPGPVFAA
                     HFHLPGEVEGPYTYGRDTNPTWTLLEQAIGELEAPGADGAQTVVFASGMAAVSAVLLSQ
                     ARAGDTVVLPDDGYQALPLVREQLAAYGVRVRTAPTSGDAQLAALDGARLLWIETPSNP
                     GLDVCDVRRLAEAARAGGTLVAVDNTLATPLGQRPLELGADFSVASGTKGLTGHGDVLL
                     GYVVCRDPGLAAGIRRWRKVIGSIPGPMEAWLAHRSLATLQLRTRRQWSNALAVAEALT
                     GRAEVTGLRHPGLPGDPSHATAARQMQGFGSVVSFTLPDRAHAERFMAALRLVEDATSF
                     GGVRSTAERRRRWGGDAVPEGFIRFSAGIEDEDDLVADVLRALDDAAAAGP"
ORIGIN
        1 gccggcgggg cgcccgcgca gggcagcggc cacgccgact acacgcccac ccagcgcgac
       61 ctgccggtca tcacccgcgc ggccgtcggc ggcccgggtg acaccgtcca ggtccagtac
      121 gccccccagg actccccgac cgggcccggg ccgctctacg tcgtcggcga cgtccacggc
      181 tacctcgacg agctcgtcgc cgagctgcag gcgcagggcc tcatcgacgc cgaccggcgc
      241 tggtccgcag gcaacgcccg cctgtggttc ctcggcgact tcaccgaccg cgggcccgac
      301 ggcatcggcg tgatcgacct ggtcatgcgg ctctccgccg aggccgccgc cgccggcggc
      361 tactgcaagg ccctcatggg caaccacgag ctgctgctca tcggcgccaa acggttcggc
      421 gacactcccg tcgcctcggg cgccggcacc gcgacgttcc aggcggcctg gctgctcaac
      481 ggcggccagc gcaccgacat ggagcgcctg gaggacgtcc acctccagtg gatgtcgcgg
      541 ctggacgccg ccgtcctcga ggacggccac ctgctgctgc actcggacac gaccgcatac
      601 ctcgactacg gcgactccgt cgaggacgtc aacgacacca tccacgagct gctcaaccgg
      661 aacgacgccg acatcacctg ggacctgttc cgcaagttca ccaagcggtt cgccttccgc
      721 gacgaggaga cgggccccca ggcggtccgc gagctcctct ccacctacgg gggcagccgc
      781 atcgtgcacg gccacagccc catcccgtac ctgctcggcg aggtcggcac cgaggacggc
      841 gacgagtccc gcggccccga ggtgcacggc ccccacgtgt acgcggacgg gctcgccatc
      901 gcgatggacg gcggcgtcac catggccggc aagctcctgg tgcagcaact gccgctcgcc
      961 gactgacgct tgtcacgagc ggggcaattc gcgaaacccc ctgtcacggc gcggcatggg
     1021 ccctctacca tcgctctgtc cgtagcaggc tctcctccgt ctgcgccggc tgaccccgaa
     1081 tccacgcggg gaaaccggcc gccacggaac atcgggggat gcacatgaac agcgctccgc
     1141 acctgctggc cgaggaccgc cccgaattcg accggctcct cgacgaggcg ctgcgcaccg
     1201 cacacgagcg gcccgagctc gccgcgctcg gcgagcggct gagcgccgga caactgcggg
     1261 ccatggcggt cggggccagc gccctgctga ccgccgcggc agcggccgag tacgaccgct
     1321 tcgtacaggt gcgcgatgca cgacgcacgg agatccgctc gacgccgcgg tcgggaggct
     1381 ccggggacgc cccggaggag agcggcgccg ggctcagcgc cgtcgtcgcg gtcctggcgc
     1441 cggtcctcgc agccgccgcc atgctcatct tcctgctggt cggctacgtc ctgaaggcga
     1501 tcgagcccga acccgccctc gcggacaccc tgctgacggc ggggtggttc ttcggggcac
     1561 tgacggcggt caccctgctc ggcgcggtcg tcgggctgct ggtgacggcc ctgcggaacc
     1621 gggcgacgga ggtcgtggca ggggacgagg accgggccgc gcccgacgag gtctccctgg
     1681 cccgcgaggc ctggcggcag gcgctgctgg agcggggcat cctgccgttc ctgcgggacg
     1741 ccctggccgc ccccggcgcg gggccggagc atgccgcgcc cggcacgccg acggccgggc
     1801 gcatccccga tctgggatac acccggcccg acttcagcag tccgcggtcc cctgcgcagg
     1861 gggcgcggcc cggctacacc gctccggact tcagcggccc ggagttcggc agtccggggt
     1921 tcggcagcgc gagccgcgag ccgctctgac ggagcggagc tgctctagtt cacgtctgcc
     1981 ggacggaggt tcatgtcctg cggtgagagg gacttgttcg cgaaccgggc gaggccgttg
     2041 gccccggcgg ccggctgcgg gtccgccgcc gtccacacct cgttgcaggt gagagcgtcc
     2101 ggtgtgcccg ggttgatggt gcagctcgtc tcgtagatct ccccgccggt ggtcagcacc
     2161 tcgatgttga cgatgttggc ctgtgaggag accgacacgg cgcaggcgtc cgtcgggtac
     2221 gtctcgccgg tgtccgtcag gtcgtaccag cgccacgggg tgggggcagg cgtcaggtcg
     2281 cggatgccgg cgtaggtgac cgtgtcggcg agcaccgcct tgacctcgcg ggccgccgca
     2341 ggccggacgg cgtccacgtc gaagcactgg ccgctggcgc cctgggggcc ggtggcgccc
     2401 gtcgggcccg tcgcaccggt cgcaccggtc gcaccggtgg ctccggtacc ggccggtccc
     2461 gtcggacctg tcggacccgt cggcccggtg gcgcccgtct tgcccttggg accgcgcgga
     2521 ccggtgggcc cgaccttgca cttgtcaccg cccgcgggct gggcagagac cgccggcggg
     2581 tccgtcgcct tgttcgccgt cgcaaggtcg cagtggtcgc cggtgtccga caccaccgcg
     2641 ccggagggct gcggggctcc cacggcggca ggggcggcga cggccgcacc catgaccagc
     2701 gccagggagg cgaaggtgcc gccggccagc cagcccgccc ggcggggcag cggccccagc
     2761 gacgatcggg tcctgtcctc agaactcatg tagcgctcct cctgcacatg ggatcgaatg
     2821 ccttcccgaa gccctcacgc gaacgcggac tccgcgagga gacactctgt gcaggcccct
     2881 ccgccgccgc agcccggctc gcccgccggt cattaaaacg gacgagcaca aagggccact
     2941 tggccgcggg cggggcagcc gcccggggcc gccgtccggc gtgccgcccc gtggaggcgg
     3001 tggcacgtcc ctagggtcgg cggccgtgaa gccgaccatc tgcctctgca tgatcgtgaa
     3061 gaacgagtcc gccgtcatcg agcgctgcct ggactccgtg cgggacctcg tcgacacctg
     3121 ggtcatctcc gacacggggt cgacggacgg cacccaggac ctcatccgca aggcgctgca
     3181 cggcatcccg ggcgagctgc acgaggagcc ctggaccgac ttcggccaca accgcagcct
     3241 caacatcgcg cacgcccgcg gcaaggccga ctacctcctg ctcctcgacg ccgacctcgt
     3301 cctgcggcgc aacggcccgc tgcccgaact cacggcgcag tcgtacatgc tgcgccacga
     3361 gggcccgacg gagtaccgga tcaaacggct ggtccgcggc gacctgccgt ggcgctacga
     3421 gggggccact cacgagtacc tgacctgcga ccgccccggc gagtacgagg accgcccggg
     3481 cgtgcaggag aacctggacg cgctctccat cgtggaccac gcggacggcg gctctcgcca
     3541 cgacaagttc gagcgggacg cccggctgct cggggccgag ctggagcggg acccctccaa
     3601 cacgcgggcg gtcttctacc tcgcccagac gatgcgggac atgggggaga ccgccgaggc
     3661 catccggctc tacgagcagc gcgccgccat gggcggctgg gaggaggagg tctattacgc
     3721 cctgctccag tccggcgtcc tgcgcgccga gtccggtgac tggcccggcg cgatggacgc
     3781 cctcacccgg gcctgggaaa cccggccgac ccggttggag gcctgctacg aactggccgc
     3841 gcggcttcgg gtgcagggcc gccaccacgc cgcacacgcg gtcaccaccg cggtcctgga
     3901 ccggccggcc ccgccggacc tgctgttcgt gcacccctgg gtgtaccgct ggggactgct
     3961 cttcgagcac tccatcacgg cgtactgggt cggcgacatg gacgcctcgc tgcgcgcctg
     4021 cgaccgcctg ctggcgctac ccgacctgcc ggaggtctac cgccggcaga ccgaggcgaa
     4081 ccgcggcttc gcgctggcgg gcggcggctc tcctgatcct gtttcacgtg aaacatcgcc
     4141 ccggcagccg accggggtct gagccgcctc acccgggtcg cccgaccggc ggccccgggg
     4201 accgccggga cgacggcgcg gggcaggccc gcggctcccc cccatgggtc gcgggtccgc
     4261 cccgtcggtc cggcgggggt cagtccgcga gcgggaggta caccctgttg ccgctcgccg
     4321 cgaactcggc ggacttctcg gccatgcccg cctggatctc ctcggccttc aggtctccgc
     4381 cgtgctcgcg gcggatgtcc tgcgagatct tcatcgagca gaacttaact agaagtgcca
     4441 catgctagat tgctggctcc gttccgtcag gaagcagagg ggggccagtg gccacgagag
     4501 acgaggtagt cagcaagctg cgcggggtgc cggccgaggt gccgagcgtg cccgaggtca
     4561 tggcgatgct cgccgcgaac ccgaagatga ggtgcgtggt ctgctacgcc cgcatctcgt
     4621 tcgacggccg agccaaggac gcacacggca tcgaggacca gcaccgcgag cttggcgaga
     4681 aggccaacgg cttcgaatgg ctggtggtct accggtacac cgacaacgac aagagcgcga
     4741 gcaaggaaga agtcgtgcgc gacgacttcg agcagatgct cacggacctc acggcgggcc
     4801 ggacgccgga gggctacccc atccacggtg tcatggcgat caacgatgac cggctctacc
     4861 ggcgcccggg ggactgggaa aggtacctcc gcgccttcac ggcccacccc gatcgggtct
     4921 actacgactc caacggacac caggacctgt acgccgaggg cttcgaggtc aagggactgg
     4981 tgggggtggc catgtccctc gccgagacgc ggaagaagca gcgccgaagc cgcaccagcc
     5041 accgcaaccg cgcgatccgc ggacagtcgg tgtccgcgtg gcggccgttc ggctgggacg
     5101 acgacaaggt atcgctccgg ccggcggagg ccgacgccat ccggaaggcg gtcaaagacg
     5161 tgctcgcagg ggcgtccctc agcgaggtga cggcccagtg gaaggaagcc gggttcacca
     5221 ccagccgggg taacgcgttc cagtacgcca ccgtgaagca ggtgctgctg aacgcccggc
     5281 tctgcggata ccgcgagatc gtcggagaac tggtgcgcga cgaggacggg caaccggtcg
     5341 tcggcgagtg ggaggcgatc gtcacgccga aggagtggtt cgccgtggtc gccaccatca
     5401 gggagcgagg ccggggcaag ggccagtcac ccggcggtgt cgtccacaag tacctgctga
     5461 caggtgtgct ccggtgcggc gccgttcggg aggacggtac ggcctgcaac aacaagatga
     5521 ccggcgtgaa ggcaaacgac tgggtcagct acagccacgg gtacctgtgc aagaagaccg
     5581 tagatggcgg ctgcaacaag acgtacaagc gcggcgacga gacggacaag cacgtctcga
     5641 cccttgtcag ggccaagctc aagcgggatg ccgccgcagc cgccaaggac gtgccggagt
     5701 ggacccggga cgaggagttg gaatcggctg tggcccgccg ccgcgctctt gagcagcgct
     5761 ggcagacggg ccagattgat gacgagacgt tcttccgcaa tctctcgccg atggaccagt
     5821 tggtgaagga gctgcgggcc gaccaggcca agcacctcgc gatggtcgcg gcagccgagg
     5881 ctgcgacggc cgacatagat acggagtggg aggcgaagac gctgacgcag aagcgggaga
     5941 tgatccagaa tgcgttgctc gccgtgatag ccgagccggg tggaaagggc cggaagccgt
     6001 tcgacgtgac gcagctcagg ccggtgtggc ggtcggcttc cgcgtaaggg tgacgccgag
     6061 gatgtccccg atccggcgaa gctgagcgtc cccgagcggg ggcgcgtcgc agacgcaccg
     6121 ttcgatccag gcgtccacct tggcttcgtc acaggtgagc gtctgagctg cgcagctcat
     6181 gcccatacct ccccttcggt cttggcccgt tccttgtcgg cgcgggcttg gttgatttcg
     6241 tggcgtgtct ggttggcgag gagttcttcg ccggggcggt agccggaggc gaggtaggcc
     6301 caggaggact cggtgacgag cacggtgtcc gggccggggg cggggtggcc ggagcgcgcg
     6361 cgggcggcct ctgcctgagc agtgcgccag gcgcggcgga catcgcggag tgcgccgagg
     6421 gtggtgaagt aggcgcggga cttggtggag aagtggccgc ggaagccgag catgtgtgcc
     6481 cacttgcaga gcttgaggtc tgcgaattcg gacaggccgc ccaggtccca ggcggtacgg
     6541 atcatctgcc ggacgtggct ctgtgcccga aggttcttga tcggctctgc ctggcgggtg
     6601 ccgtggcagt cggggcacag gtcgcggatc gtgccgccga cagtgccacg gccggagcag
     6661 gtacggcaga ccatcgtccg gtgcacggtg ccggagtcct cagcgctctt cgtggcgtac
     6721 ttcgcgacgt acccggcaac agcggcgtcg gtgagttcgc cgtcaccgag tgcggtgatc
     6781 tcccggacat cgaacttcct gccccagcgg atctcatggt cccccaccgt gtcggagacc
     6841 accgcgagcg cggttgcttc gacggcagtc ccgatggctt cgttgagggc ggccacggtg
     6901 gcgaaggccg gcggggcgct ggtgtgtccg tcggggccat cgaagcgcac gaccgcgtgg
     6961 aagtggacca agccccgctg ctgatactcg gcgaccttcg cgaaggagac ccgcagcacc
     7021 tctttcatgg ccttctgcgt catgtgcaga tgcgcggcca gcgcccggcg caggttgagg
     7081 gtgaagcgtg cccacagcgc gcccgcgtgg gcgttccaca gcacggcccc cgtgtagtcg
     7141 tacgtcttcg ggtcgagtgg ggtaccaacc tctggggcgc cctcggggtg ccaggttccg
     7201 cagcggcagg ggtagggctt gccggtgttg gtggtggggc ggttgtggac cgggccgaag
     7261 gagggggcgg tgagggtgag gaacacgcgg gggtgcgtgc ggacggtttc ggggacgttc
     7321 ttgccgccgc acagtccggc gcggacgagg tggaacgtgt cggcggcgtg gccccctgaa
     7381 catgcccgac cccaacccaa acaggacacc ggccaaagcc gctccggccg accgcgatgc
     7441 acaggtgcgg cagtcatcgc caactgccaa agcaggaacg gagttgacgc acgcgagttc
     7501 cagcgcggag ggggtgtgcc ggggctcatg taggaggcgc cgatcaggcg ttcggatgag
     7561 cgggggacgg ggccggagga cggacccccg tcaggtcctc cgcatgtcgg ctatcgccat
     7621 cccatcgcac cgccgaaggc gagcctgagc attctgagat cccttggtca aggcccgccg
     7681 cccgtcgcgt gtcagcggta ccttcgcgtc agaagcgtgg tctcagatcg gggtggtggg
     7741 tgtgagcggg tacatcgagg agcaagagcg aatcggacag cgggtacggc gtcagcggct
     7801 ctccgtcggg atgactcagg ccgatctcgc cgcagcgctc gggcggactc agggctgggt
     7861 gtccaagctg gagaagggcc ggatcgagct ggaccgggcc gggctgatca acgccgtggc
     7921 cgccgccctg cactgccacc caaacaccct gatcgagcgc ccctacacag gcggcggagc
     7981 cgagaccaag tggcaggtct cggcagcctc gatcctgcgg gaactgcgcc gctacgacct
     8041 gacgcccgtc ttcgacggta ccccgcgccc gtccgaggtg ctgtggcagg acatgaagcg
     8101 tctgctccgc ctgcgggacg cggcggcgaa cggcgctgtg ctggccgagc tgccggacat
     8161 gctgcgggag gcccgcgccc tcgccgaggt gtccaccggc catgagcgtg aagaggcgtt
     8221 cgcgatctac gcggtggcat gcaagttcgc gcacaccgcc gcccacgccc tcggacaccc
     8281 cgagctggtc gccatggctt gcgagcgggc gacgtggtcg gcgcagctct ccggcgaccc
     8341 ggtgatgccc gcaatggcgc tctggatgcg gatgtgggac acatgggcct ccgccgactg
     8401 ggacgacgcg ctcgccctcg gggacaaggc cctcgccggc atcgagacgg aatacgaagc
     8461 cggtgaccca ctcgccctgc gcatgtgggg cgccctgcac ctgcgggccg cgatctcctg
     8521 cgcccgggca gggaacccag ccgggtcgga cgaacgcatc gccctggccc ggaccgcggg
     8581 cgagcgggtc aactcctacg tcggacccga gatccatgat cggcactcgg tcacgttcag
     8641 cctcggcaac gtcatcatcc acagcgtcag tgccgccctg gagatgagcg accagacgaa
     8701 ggcgcttcgc ctcaaccgtg aggcggaccc cgcacacatt tcggttctgc cgaactcccg
     8761 tctcgggcac caccacatgg acctggcccg cgcgtggctg tgggacggca accgggacca
     8821 ggccctgacc gagctggaga ccgccgagcg catcgccccc cagctcgtcc gcaatcaccc
     8881 cgtcgctcgg gcgactctac ggaagatcgt ctatgccgag cgggtcgcta cccgccagcg
     8941 gctgcggggc atgaccggac gtttttcgct ggattgatct gcgggtattc cacagaatca
     9001 tattcgtggg tagcgggctg catacggtcc gctacatgac ctctacgcgt cgcactgacc
     9061 atgaccgcgt acgacggcag gcggacgata ctgacccccg ctggcccctg cgcggcgatc
     9121 tcgcgtacga caccgccacc tcccgcacgg gtgtggtcat agacgtcccc aacgacaccg
     9181 gcaccacggt ctaccgcctg tgtcccgagg gcggcggcgt cgcgggctgg tccgccagtc
     9241 tcgacaccct cgtgcctgcc gaggacgcgg ccccacagcc catcccccgc cggccgcccg
     9301 ccaacgagcc ccagggtcag ccggagtacg cgccctggga cgcatccagc agtcccgacc
     9361 ccagtccggg cctgcgggcc cgtgccgagc ggggcatgga gcgattttcg aagtcggccg
     9421 acgaggacga ccaggccggg agtaccgcat gagccgcctg cctcgctggc tgcacgaggg
     9481 tgcccgggtc ctggaccccg ccgaagaccg cgaggggatc gtgcagttca tcggcgagtg
     9541 ggtcgatccc accacacgga gggccatccc ccgcgcgatc ttcttgcggc ccgagggcgg
     9601 cggccgggaa tgggtcgtag ccgaccatca ggccctacgc gaggcggacc cccgatgaac
     9661 gcccgcccag gggagttacc gccgcccggc tggggcatga tcgcctccct cctcttgatc
     9721 ggtctcgctg gtcccgccat cgtcctcagc ggccaggtcc tgaacctgga ccagtcggcg
     9781 agtacacccc ctccggccac cgtgccggac gtcgaaccgc cctcgtaggc gacccacaag
     9841 ctccccgccc tggtggtcgc gcaggcacca cccgggtggg ggcaccactc cgcccgcccc
     9901 ttcccgcgcc agccgggcgg agcacggcgc cgggggttct gatcccccat gcacccccgg
     9961 cgccatccac acaccactcg ctcacaccga gaggagcacg atgcacagtg ccttacggct
    10021 cgcgaccgtc ccccggtccg tgatcatgca gccgaccacg cagtgcctcc ccatggactg
    10081 cacgtattgc tacctgccgt tccggaagat gaagaacctg atgccggtgg ccgtcgccga
    10141 ggccgtggcc acgtccgtca acccgtgggc tgccgacgat ccggcgttcg aggtggtgtg
    10201 gcacggcggc gagccgctgg ccaccggccg cgagcacctg acggccctca tggccccatt
    10261 caggggcgtg aagcactccg tgcagacgaa cgccgcactc atagatgacg catggtgcgc
    10321 gttcctgctg gagcacgacg tgcacgtggg cgtcagcatc gacggccccg cggacatgaa
    10381 cacccaccgc atcaccctcg ccggccaccc gggattccgc gtcaccatgc ggggaatcga
    10441 gcgactacgg caccacggca tcccctactc cgccatcgct gtggtctccg atcccgaccc
    10501 ggccgacgcc gcccgcttct acgagttctt cgccgagctg ggcgtgacca ccctcggcgt
    10561 caacgtcgaa gaggaagagg gagtcaacac cggctccaag gacgccgacc ccgtgcgggc
    10621 gtccgagttc tgggcggccc tcacggatgc ctggcacggt aaccccgtca tacggctgcg
    10681 cgaggtgcag cgcgtactca acttcgccgg tgccgtccta cagggccacg agaccgcccc
    10741 catgcccgcg tcctcgccgt gggatccgct gccgaccgtc gcccatgacg gcggcgtggt
    10801 catgctctcc ccggagctgg ccgggttcac cgaccctcgg ttcggtgact tcaccaccgg
    10861 caacgtgctc aaggacgact tggacgttct ggtagccgaa gccgaggagc gcaccccctg
    10921 gatcactgag ttctgggacg gcgtggacgc ctgccgtgcc acctgcccca ccttcgcctt
    10981 ctgcggaggt gcacaccccg cgaaccggta cttcgagcac gggggccgca tggacggcac
    11041 ccgtacctcg tactgcacca cctcgaagat cgccctactt gaaggagtga cgcgacatgt
    11101 ccgcacacac cgcccctgac gccaccacgc tcgtgatgga ctcggcaccg ggattcacgt
    11161 ctctgctgga ggccgccggc accgccgcca tcgcgcgctg gggaaacacc tggagcaacg
    11221 ccgacttcga gaactacctg tccgcgacca cgttcgacaa ccggccgacg tgggacaacc
    11281 ccacccccgt gttcgacaac aggcccacct gggacaactg gaagaacaag tagcgccgcc
    11341 cacaccgaac ggggcggccc tgtcagccgc gcagggccgc cccggcacca ccaaggagga
    11401 gcacaccatg gccacccgca ccttcggcca cgtcaccgtc accacgcccg acctggacga
    11461 gcccggccta tacctctcga ccgtcgacac cctcgacagc ccgcgcggcg ccctccagga
    11521 cttcacgttc ggtgacgccg acctgcgggc gcttggcctt gcagataccc agctcgtcac
    11581 cggccgcatc acgggcctgc gctccaagcg ggtcgagttc gaggccttga acctgcacgg
    11641 ggtggaaatc accggcagcg acctcggggc ggtccgctgg aacgagagca agctgacccg
    11701 cacgctcctc cgcgactgca agctgatggg ggccgccctg gacggcctgg tgctcgatga
    11761 cgtgctgttc gaaggctgca aattcgacta cgcgaccttc gaaaaggtcc gagcaacggg
    11821 gcccgtcgcg ttcgccggct gcaccttcac cgaggccaca ttcaccgact gcgacctgtc
    11881 cgacgtcgtg ttctccgaat gcacgttcag gctcaccgag ttcggcaccg gtcgctaccg
    11941 ggacaccgac ctgcgcggca acgatctctc gacaatccgc ggcgtctcca acctgtccaa
    12001 gatccgcatc gggcacgtcc agcagagcga catcgcccag gccctcgtga acgaactcga
    12061 catgaccctc ggcgacgact gagccaggag gaccagtgcc cttacacgta gccttcaccg
    12121 accggggcgg cttgcggggg cggtgcgacg tcgctgcggt ccgcaccgtc atcggggatc
    12181 ccgccttcga agacggggcg gtcgtaccgt ccgggctgtg gcagccgctc agcgagtctg
    12241 ccgcccaagc gctgaacgcc ccgccgtgga ccccgccgag cacgctggtg gagatcgtcc
    12301 ggccgccagc accgaacggc gggaagctgg aagacctggc acagcagata ggcgacgaac
    12361 aggcccagta cctgggtcag gccctcgcca agcccgacat gatcaccacc accgagaact
    12421 accaggacgg ccgcctcatc ggcctccatc tcgacaactg ggacaagctc aattacgggc
    12481 agaagacgac cggccgacgc cgcctcgccc tcaatctggg ccccggaacc cggtacatcc
    12541 ttctgggcgc cctcgacgcc caagccgtct gccgggcagt ccaccccgag gactatgcgt
    12601 accgctgccc cagcacggac gactaccgcg cccacgtcgc cgcagggcac cccatccggt
    12661 gcatccggat ccgacttgca cccggcgagg gctacatcgc ccccacggag tacctgctac
    12721 acgacggctc caccgataac caggaccagc cgtcggccat ggccttctgg ctcggccgct
    12781 ggcagcgcgg caccctgccg tccctcgtct gatcgcgacg ccgccacctc ggtcacatcg
    12841 accccgcgcg ggtggactac cgcttcaggt cgtctggcct ggggcgccgg ccggaggggc
    12901 tgacacacat ggtcccggtt cgaagtggcg gaaccgggga ccatgtgctg aaggacgatc
    12961 tatcgtctga agatcagtcc acagaacaaa cgaaggctga ccgacgactc cccccggatg
    13021 ccgtcggtca gccctattta cgcaggtcag tcagccagcg gcaggtacac acggttaccc
    13081 gaggccgcga actccttcga cttctccagc atcccggcct cgacctcctc cggagtgacg
    13141 tccgcttcac cgccgaactg ctctgtgatg cttctgctga tcttcatcga gcagaacttc
    13201 ggaccgcaca tggagcagaa gtgcgcggtc ttggccggct cggccgggag ggtctcgtcg
    13261 tggaactcgc gcgccgtgtc cgggtcgagg gccaggttga actggtcctc ccaccggaac
    13321 tcgaaccgcg cgtccgacag ggcgtcgtcc cactcctggg cgcccgggtg gcccttggcc
    13381 aggtcggccg catgggccgc gatcttgtac gtgatgacgc ccgtcttgac gtcgtcgcgg
    13441 ttgggcagcc ccaggtgctc cttgggcgtg acgtagcaga gcatggccgt gccccaccag
    13501 gcgatcatcg cggcgccgat gcccgaggtg atgtggtcgt aggccggtgc cacgtccgtg
    13561 gtcagcgggc cgagcgtgta gaacggcgcc tcctcgcaga tctcctgctg gaggtcgatg
    13621 ttctccttga tcttgtgcat cggtacgtgc ccaggaccct cgatcatggt ctgcacgttg
    13681 tggcgcttgg cgatcgtgtt cagctcgccg agcgtcttga gctccgcgaa ctgcgccgcg
    13741 tcattggcgt ccgcgatgga accggggcgc aggccgtcac cgagcgagta ggtgacgtca
    13801 tacgccgcga ggatctcgca gagctcctcg aagttcgtgt agaggaagtt ctccttgtgg
    13861 tgcgccaggc accacgccgc catgatcgag ccgccgcggg agacgatgcc ggtcttgcgg
    13921 cgggcggtca gcgggacgta cggcagcagc acgccggcgt ggaccgtcat gtagtcgacg
    13981 ccctgctcgg cctgctcgat gaccgtgtcc ttgtagatct cccaggtcag ctcctcggcc
    14041 ttgccgtcga ccttttccag cgcctggtag agcggcacgg tgccgatcgg cacgggggag
    14101 ttgcgcagca cccactcgcg cgtggtgtgg atgttgcggc cggtggagag gtccatcacc
    14161 gtgtcggcgc cccagcgggt ggcccaggtc atcttctcga cctcctcctc gatggaggag
    14221 gtgacggcgg agttgccgat gttggcgttg accttcacca ggaaccgctt gccgatgatc
    14281 atcggctcga tctccgggtg gttcacgttg gccggcagca cggcccggcc cgccgcgatc
    14341 tcctcgcgca cgacctcggg ggagacgttc tcgcggatag cgacgtactc catctccggg
    14401 gtgacctcgc cgcggcgcgc gtacgcgagc tgcgtgactg cctggcctcc gcggccccgt
    14461 cggggcaggc gcgggcggcc ggggaacacc gcgtcgaggt tcttgaggcc cccgcgcggc
    14521 gacgtgtgct tgatgccgtc gtcctcgggg cgcaccgggc ggcccgcgta ctcctccgtg
    14581 tcgccgcggc cgatgatcca gttctcgcgc agcggcggca gcccgcggcg cacgtccgtc
    14641 tcgatctggg ggtcggtgta cggcccggac gtgtcgtaga gcgtcacgtc cttgccgttg
    14701 gtgaggtgga cctggcgaac cggcacgcgg atgtcggggc gggagcccgc gacataaccc
    14761 ttgtgccagc ccggctggcg ctcggtctgg ccgtcggcgt cccggccggc ggcaggcgtg
    14821 cgtgcgtcct gaatggtcat gagacctgat ctccctacgc cggcattacc cggtaacagg
    14881 ttcggcggtc ggcgcagcct cctcccgtac gcatgtccgc gcgtacggtg atcagcgccc
    14941 tctcagcccg gtgctccgag ctcccgcgtt gtgcaaaggt gcccccacgc tagcgtcatc
    15001 tgtggcgtgc tgaacagtgg gccccctcat ctcttgcgat gatcagccgg tgacgccctc
    15061 gacgatgccc tccggcgagc ccaccgatcc gcacgagccc ccgccctcgg acggccgcgc
    15121 accgaacggc cgcggccgct cccccgaacc gggccactcc cacggccacg ggcacgtgca
    15181 cagccacgcg cacgggccgg cggcgcccgt ctcgaagcac ctgcgcaagg tcatcgcggc
    15241 cgtgctgatc ccgttcgccg ccgccgtgtt cgtcggcatg gccgtgctct ggccgaacgg
    15301 cgctcccgcg cacgagcgct ccggggtggg cttcgaccgc cagacggagc aggcgcgcgt
    15361 ggtcgcggtg gagacggtcg actgcaaatc ggtgaacgcc tcccaggtgc cgccgaccgg
    15421 cgacacctcc acgccgtcgg gccgcgaggc ggtcgccggg cagaacggtt cctgcaagaa
    15481 ggccacggtc gaggtcggca ccgggcccga caagggacgg accttcttcg agatcgtcca
    15541 gccgggcgcg ccgcgccagt tggccgaggg gcaggaggtc gtcgtggcgt acgcgccgga
    15601 cgcgccccgc gacctccagt actcggtcat cgacgtcaac cgcaagctgc cgctggccgt
    15661 gctcgccggc ctcttcgcgc tggtcgtggt cctggtgggc cgtatgcgcg ggctgttcgc
    15721 gctgatctcg ctcgccatca gcttcaccgt gctgacgctg ttcatcctgc cggcgatcct
    15781 gcagggcgcc aatccgctgc tcgtggcggt catcggggcc agtgcgatca tgctggtcgc
    15841 cctctacatg tgccacggcc tgaccgcccg gacctcggtc gcggttctgg gcacgctcgt
    15901 gtccctgctg ctgatcggcc tgctgggctc ggtgttcatc gactgggcgt tcctcagcgg
    15961 caacaccgac gacaacaccg ggctgatcca cggcctctac ccggagatcg acatgagcgg
    16021 cctgctgctc gcaggcgtca tcatcggatc gctgggcgtg ctcgatgatg tgacggtcac
    16081 acagacgtcg gcggtgtggg aactccacca ggcggacccg tcgatggggc cgcgggccgt
    16141 ctacctggcg gccattcgca tcggccggga ccacatcgcg tcggtggtca acacgctggt
    16201 cctggcctac gcgggcgcgg cgctgccgct gctgctgctg ttctcgatcg cgaacagcag
    16261 catggggtcg gtggcgaaca gcgagctcgt cgcggaggag atcgtacgga ccctggtggg
    16321 gtcgatcggc ctggtggcct cggtccccgt gacgacagcc ctggcggcgc tggtcgtctc
    16381 cgcggaccgg cccggctccc aggccgccgg cggcgccccc gcggcgggcc ggggcgggcg
    16441 ggggcgccgg cgcaagcgct gatccggccg cggcgctagc ccgcgttctg ctcgttctgc
    16501 cgcgcctcgg acaggatccg gtcgagggcc tcttccaggc tcccttcgaa gtcgccgagg
    16561 ctgcgctcct ggccgagcgg aacgatccgg tcggtgcggt cgaggaaggc cacgagcggg
    16621 gcggcgccgg cccggaacag cgcccggtcg ctgccgacct ggagccggat gtggacgtcc
    16681 gacaactcgt cgggggaggt gggggcgacg tgcacatctc cctcgccgca cggcttgttg
    16741 atgccgtcga ggaggagttc ccgcccgaat gcccaggtca ccggcgcatc cccgggaagg
    16801 tggaaggtca ggcgcaccgc atacgggtcg ccggcgtcat accggagctc caccgggatc
    16861 cggaacgaga gctcctcgga aacgaggaag ctcatcatga cctctgcctg aaccgattcg
    16921 cgcattgcct accccgctgt cgtggaagtg gccaggaatg accccccgag accctcttga
    16981 caagggtggt ggaagctgtc gcggatcaca aggagtgagt tttcagatac tgatagagaa
    17041 cgagagggtg ctcaacagcg cgcctacttc actccgtagt cgtgcgacta cacacggcaa
    17101 cttctccgcc tggtgcaagg ggagagaaat cgccatggtc gccgcggtgt cccccgcggt
    17161 gatcgggatg gccgcgcaca ccgtgcccag cgcgtactcc tggtgctccg tcaccggctg
    17221 catgcggccc agcgatccga tgcgctgctc cagcgcgcgc tggtcccgca ccgtgtacgg
    17281 cgtgatggcc tcgacggggt gccggtcgta gtagtcccgg cgggtctcct cgtccaactg
    17341 ggccagcagg cactgcccga tcgcgtgggc gtggccggtg gcgcggaagt ccgcccactc
    17401 ctccaccgcc gggtcggagg gcgtgtccga gacgcccacc acctcgatct ccccgtcccg
    17461 gaacaccgcg aagtacaccg gggcgccgac cgcgtcgcgg aagtgggcca gcgagtcgag
    17521 aatcatgctg cgacgtttct gctgcacccc gccgccggcc agccgtccgg ccgcggcccc
    17581 gaggacgaac acgccgccct cgcggcgcag gtatccctcg taggtgagcg tgcgcagcag
    17641 gtggtatgcg gtgggcagcg ggaggccggc ctcacgcgcg agctgcttcg ccggggctcc
    17701 cccgctgtgg gagcccgctg cttcgagcag ccgcagcgcc cgctgcaccg aaccgatcag
    17761 cgtggacaca ccggcattgt gaaccggaga cacagctcac ccccaggcct ggcggcgggc
    17821 cagagggccc gccctgcggg ggccgccccc gccacacgcc gcgggtcctg ggggtcatgc
    17881 tcgggccatg agtggcgtag ccgcaggtca cagcggtgct ttcggcgttc gctcccagga
    17941 gcggcacagg cgcgactcta tccaccgtcg cgcgcgccgt gagcttccgc atgccccacg
    18001 ttcccccact cgggttaacc tcggcggacc ctgcagccgc tccgccgcag cggcgccgcc
    18061 cgtcgctacc agtcgcgcga ggaggacttc gtgctgctcc cgccgaactt cttcaccagg
    18121 aagaccagtc cgccgacgag cgccacgaac agcagcagct tgaaggcgaa cccgatcagg
    18181 gcaccgagga tgcttgtgat gacgccgccg aagacgaaca gcaccagaag ggggatcgca
    18241 acccacttca cccaccaggg catgccggcg aacgtttctc ggatgccgtc catggctcga
    18301 cctcttcctc taccgcccgc gtgtccgcgt gcgtgtcgca tgtcgtcgta cggtcgtgtt
    18361 tcctgactcg atgctaggag gccgaggacg ccgacggggg cccgcgagcc cccggagtcc
    18421 cctgatccgg cccttagggg actccggggg ccaccccgga gccggaccct ccgcgggccc
    18481 ggtgccgcgc ggtcaggcct ccggcgggga gaacaccacc agcaccttca ggtcctcgct
    18541 gatgtggtgg aacttgtgcg ggaccccggc cggcacgtag acgacactcc cccgggccac
    18601 cgtcgtcgtc tcctccccga ccgtgatcga ggcgcggccg ctcacgacga agtacacctc
    18661 gtcctggcgg tgcggctgct gcgggtcgct ctggccggcg tcgagcgcgt acaggccgac
    18721 cgacatgttc ggctcgcgca ggaactgcag gtaggcgccg tcgttcgcga ggcgctccgc
    18781 ctcgagctcg tccagccgga aggccttcat cgtcgttgtg cccctcgtgt tctcgtgtcc
    18841 cggcatcagc ggatccgccg atgtcccacc aggatcttct ctgccacgat cagacacatg
    18901 acgaatttcg tagtcaagac gctggcgaac gccgccgccc tcgccgtggc catctggctg
    18961 gtctccggca tcacgctgga cgaccactcc agctccctgg ggcacaggac gctgaccctg
    19021 gtgctggtcg ccctggtctt cgggctggtc aacctcatcg tcaagccggt cgtgaagttg
    19081 ctgtcgctgc cgctcttcgt cctcaccctg ggcctgttca cgctcgtcgt gaacgccctc
    19141 atgctgctcc tgacgtcctg gctggccaag cagctcgacc tcagcttcca cgtcgatggc
    19201 ttctggagcg ccctgctcgg cggcctgatc atctccgtcg tgtcgtgggc cgtgaacctg
    19261 gccctgcccg acaaggactg accggccgca gggcccgccc accgtgaagg agcacaccgc
    19321 atgaacggga acgaccgcac cgggggccgg gcctccgcgc ccaccgcggc gggggagggc
    19381 acccgcgccg tgcgggcagg ccttccggag ccggtgaaga acgagccgcc gctgcccggc
    19441 cccgtcttcg ccgcccactt ccacctcccc ggggaggtgg agggcccgta cacctacgga
    19501 cgggacacca atcccacctg gaccctgctg gagcaggcca tcggcgaact ggaggccccc
    19561 ggcgcggacg gcgcgcagac cgtggtcttc gcctccggca tggccgccgt ctccgccgtc
    19621 ctcctctccc aggcccgggc cggcgacacc gtcgtcctgc ccgacgacgg ctaccaggcg
    19681 ctgcccctgg tccgcgagca gctcgcggcc tacggggtcc gcgtccgcac agcccccacc
    19741 agcggcgacg cccagctcgc cgccctcgac ggtgcccggc tgctgtggat cgagacgccc
    19801 tccaatcccg gactggacgt ctgcgacgta cggcgcctgg ccgaggcggc acgggcgggc
    19861 ggcaccctgg tggccgtcga caacacgctc gccaccccgc tcgggcagcg gccgctggag
    19921 ttgggcgccg acttctccgt ggccagcggc accaaggggc tgaccggcca cggcgatgtc
    19981 ctgctcggct acgtcgtctg ccgcgacccc ggactcgcag caggcatccg gcgctggcgc
    20041 aaggtcatcg gctccatccc gggccccatg gaggcctggc tcgcccaccg ctccctggcc
    20101 accctccagc tgcgcacccg ccgccagtgg tccaacgccc tggccgtcgc cgaggcgctg
    20161 accgggcggg ccgaggtcac cggtctccgc cacccgggac tgcccggcga cccctcgcac
    20221 gccacggccg cacgccagat gcagggcttc ggctccgtcg tctccttcac gctgcccgac
    20281 cgggcccacg ccgagcggtt catggcggcg ctgcgcctgg tcgaggacgc gacgagcttc
    20341 ggcggtgtcc ggtccactgc ggaacggcgg cgcaggtggg gcggcgacgc cgtcccggag
    20401 ggcttcatcc gcttctccgc cggcatcgag gacgaggacg acctggtcgc ggacgtgctg
    20461 cgggccctcg acgacgcggc cgcggccggt ccctgagcag gcgcggaagg cggtccgagc
    20521 ctcccccctc ctggctcgga ccgcctccgg gttccacgca agaaccacgt gtcccaggct
    20581 agttgaccgt gcgtcagagt ccaatcaccg tagcgacagg ggcctatcgg catatttata
    20641 gtggaaggcc caccgagagg ggccgccatg gacctggccc tgctgcgcac cttcgtggcc
    20701 gtgcaccggg cgggctcgtt cacccgggcc gccgccctgc tcgggctgtc gcagcccgcc
    20761 gtcacctcgc agatacggac gctcgaacgc caactggggc gccccctgtt ccaccggcgc
    20821 tcccgcggtg tcaccccgac cgccgtcggt gacgagctcg cccacaaggc cgcgccgcac
    20881 ctcgacgccc tgctgcggat caccgaggcc gagcgggagg cggccggcgc ccagcggacc
    20941 ctgcacctcg ccggtccgcc cgagttcctc tccctgcgcg tcctgcccgc gctcgccccg
    21001 ctcgtcggcc agggccacgc cctgcgcacg gcgctgcgga ccgacgccgc agaagccctc
    21061 gacggcctcg cctccggcca ccacgacctc gtcacgacca ccgtccggcc gcgcggcggg
    21121 ctcttcacgg ccaccgccct ctgcgacgag gagcacctcc tggtcgccgc cccgtactgg
    21181 gcggcgctcg tcgacccgga ccggctgcgc gaggccgggc cggccaccct cgacggcatt
    21241 ccgctggtcg aggtgcacga gagcatgccg ctggccacgc ggtactgggc ggccgtgttc
    21301 gagagccggc ccgacacccg gcccgacgcc gcg
//
