LOCUS       NZ_CP030862            21248 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces globosus strain LZH-48 chromosome, complete genome.
ACCESSION   NZ_CP030862
VERSION     NZ_CP030862.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces globosus
  ORGANISM  Streptomyces globosus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6863360)
  AUTHORS   Ran,K., Li,Z., Wei,S. and Dong,R.
  TITLE     Draft genome Sequence of streptomyces globosus LZH-48
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6863360)
  AUTHORS   Ran,K., Li,Z., Wei,S. and Dong,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2018) Institute of Biophysics, Dezhou University,
            566 DaXuexi RD, Dezhou, Shandong 253023, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Portal v. version 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003325375.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:22:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,671
            CDSs (total)                      :: 6,576
            Genes (coding)                    :: 6,458
            CDSs (with protein)               :: 6,458
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 41 of 118
            Pseudo Genes (incomplete)         :: 101 of 118
            Pseudo Genes (internal stop)      :: 11 of 118
            Pseudo Genes (multiple problems)  :: 32 of 118
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:39:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4396346
            Orig. end                         :: 4417594
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030862.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21248
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="amglyccycl"
                     /region_number="25"
                     /rules="(DOIS or ValA or salQ or strH or strK1 or strK2 or
                     NeoL or SpcFG or SpcDK_glyc)"
                     /tool="antismash"
     cand_cluster    1..21248
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /kind="single"
                     /product="amglyccycl"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21248
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11248](-)"
                     /cutoff="20000"
                     /detection_rule="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11248)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="1"
     misc_feature    203..216
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    complement(390..404)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     gene            complement(664..1833)
                     /locus_tag="C0216_RS19325"
                     /old_locus_tag="C0216_19305"
     CDS             complement(664..1833)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385513.1"
                     /locus_tag="C0216_RS19325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19305"
                     /product="acyltransferase"
                     /protein_id="WP_114056494.1"
                     /transl_table=11
                     /translation="MPSSPVPPARPPLPSLTGLRFVAAALVFFFHASLVFISMNPFADE
                     DVADGFRWLFSKAGWMGVSFFFVLSGFVLTWSAKPGDTATGFWRRRLLKIFPNHIVTWA
                     ATIVLFAGTAVPAHVWLPNLFLIQSWFPDPAVHMGLNTPAWSLCSELLFYLLFPLLIGP
                     VLRIRERALWGWAAAMAACMALVQLATDFLAPASPPAPGTDVTVWQFWFGYNFPPMRMF
                     EFVLGMLLARLVLAGAFPRVRVLPAALLCVAGYAAALEVPFLYGLTLTNIVPISLLICA
                     VARADADGTPTGLRSRTMQWLGEASFGFYLVQQIVLSFTRTTLMDHRTYSVPVGIAVIA
                     AEFAASLVLGRLLLLCVERPLMQRWARPRRKQPAAPAEAPSQRSLTHAS"
     gene            complement(1870..3069)
                     /locus_tag="C0216_RS19330"
                     /old_locus_tag="C0216_19310"
     CDS             complement(1870..3069)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="C0216_RS19330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19310"
                     /product="MFS transporter"
                     /protein_id="WP_162793267.1"
                     /transl_table=11
                     /translation="MAVLILAIFCVGTAELAPSGMLGDLAEDLSVTIPTAGLLVTVYAL
                     TVVVAGPLVTAASTRIRRKYLLVALLLVSVAGNVLSSLAPTFALLVAGRMLTAVIHGTF
                     LAVCVVTAGGMAAEGKEGSAVAATQLGVNLATVLGVPLGTLVAQQLHWRATFGSVAVLA
                     LAAAALILLVIPDDGRTAGSSAAHELRVFKEWQVVGTVLATVLCSAGMFTLITYMVPLL
                     TDVGGFPAAWVPAVLVAYGIGSVAGNALGGRYADRSADRAVLRLSWTLAAVCLLYWAAA
                     PYAAGGAVFLLLFSMATFALIPGLQTKVLSAAADAPTLSLTANMSAFGLGAALGSWAGG
                     RLIDQGLGTRAVTLGAAAFTALGALLIAQTVYAGRRRAAATAAAAEPATATAATAAPAS
                     "
     misc_feature    complement(3085..3101)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.32"
                     /tool="antismash"
     misc_feature    complement(3239..3253)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 13.93"
                     /tool="antismash"
     misc_feature    complement(3261..3277)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.82"
                     /tool="antismash"
     misc_feature    3270..3283
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.16"
                     /tool="antismash"
     gene            complement(3341..4573)
                     /locus_tag="C0216_RS19335"
                     /old_locus_tag="C0216_19315"
     CDS             complement(3341..4573)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603452.1"
                     /locus_tag="C0216_RS19335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19315"
                     /product="MFS transporter"
                     /protein_id="WP_114056496.1"
                     /transl_table=11
                     /translation="MSPAAATAAARRPAGATAARLAVLAAATFVYVTFEVFPVGLIRDI
                     ARDLDVSEGRVGLLISGYAVVAAVVTVPAVALASRMSRGTALAASLVVLFAAEVLAAAS
                     TGFAMMAVSRVAAALTHGVLWSLVAPAAAAMVPRGQVGSATAAVFGGASLAAIVGSPGT
                     TLVGGLIGWRATALLLAAATAAVTCALVWAVRPGAAAAVPEDTARAGAGGDARGQVDWP
                     AVLRLCGTAVALVTAHFLSYTYFAVIVADAAGGGAGPVTALLAAFGVAGAVGTYLIGRH
                     GDRAPQRAAAVTMAAFTAGVALLALAFAPVPPAARLAAAAVAVAVWGGAFAAAGPVFQT
                     GVMRLAAGDADRASSVYVTGFQVGIAGGSALGAALLGGPTALLPAVSAVLAAAVLAVVL
                     LRRPIPSARLT"
     gene            complement(4570..5604)
                     /locus_tag="C0216_RS19340"
                     /old_locus_tag="C0216_19320"
     CDS             complement(4570..5604)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024989.4"
                     /locus_tag="C0216_RS19340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19320"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_114056497.1"
                     /sec_met_domain="ADH_N (E-value: 2.1e-22, bitscore: 77.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.7e-16, bitscore:
                     57.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIQLTGPRAVSVAEVEPPAPGPGEVLVRVALLGLCGTDLGFYD
                     GTSNYLRDGWKSYPFVPGHEWIGTVVGLGPGADPELAGQRVSGHNFRPCGTCPHCRAGR
                     IRYCPDRSEIGVLGDCPGAGAELITAPADTLTRIPDSLSDEAGALLEPTAAAVHAIDRL
                     AVGARDRVAVLGGGTLGLAAAQVARALGADPVVFDPQPAARDLARRLGLRASAAPAGPD
                     EERYDAVVEASGSTAAVRAAVRLVAAGGRMAQLGTPHHAVDGFDAAALVIRDATVHGVL
                     SGIGHWDRLVALVEEGAVDLDALVDRVFPLTAPDAAFACLADGARTRPKILVRMDAAAA
                     GAGR"
     gene            complement(5601..6392)
                     /locus_tag="C0216_RS19345"
                     /old_locus_tag="C0216_19325"
     CDS             complement(5601..6392)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385519.1"
                     /locus_tag="C0216_RS19345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19325"
                     /product="TIM barrel protein"
                     /protein_id="WP_114056498.1"
                     /transl_table=11
                     /translation="MTPAVAAPQWRIGTDRRRAARTALAAGADLLHLDYGGAHRGTPLG
                     EPAALREAAAIAGDIPVPVLAVNHVNDLGLAEERGTANPAALALLERAQDCALRLGAGV
                     LHVPGFRRSTPATAGLRAGTADALRTLCERAASAGLVLAYESPLGHRDLLALARRVDHP
                     ALRLVLDTGNLRDAGEDPLAFAREAGAAGLLLPDLHVKDPAAGPAAPGSAFAELPALLA
                     RSAARSVLVENDYRGAGAARLPEDIRLCRAAAEPTRPEDPR"
     gene            complement(6389..7483)
                     /locus_tag="C0216_RS19350"
                     /old_locus_tag="C0216_19330"
     CDS             complement(6389..7483)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385520.1"
                     /locus_tag="C0216_RS19350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19330"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_114056499.1"
                     /sec_met_domain="ADH_N (E-value: 9.8e-07, bitscore: 27.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAATHRALRRLPADARGRTRVEVAEVPTPPLAPGDMLLAPLTAG
                     ICGTDWQILRGLRRDPSPVPGHEGVARVVEPGDSGLPAGRLVTVNPTHPGDPSFLLGHN
                     LPGLWAERTRIPAAAVRAGLVLPVPDGAAAPRAAALAEPLASVLYGLRIARHTVRPAAL
                     AVWGDGTVGRLAREAWRRELPGLRTLLVGHGADAVHPLDPGLPHMLAGLPGPVAAVIAT
                     PRTGTRQALAALDRHVRGTLLVDVHAGLPEGPVPLTAGPVDVAALRADNCGGRPWPPRV
                     HRLDRPAGPLLLYGHRGVGGEHLRQAFDLLLASGSAPAGAGVLTHTVDLEGAAGLVNSV
                     LDADDRSAGGRRVLKAAILIGGPA"
     gene            complement(7480..8496)
                     /locus_tag="C0216_RS19355"
                     /old_locus_tag="C0216_19335"
     CDS             complement(7480..8496)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603456.1"
                     /locus_tag="C0216_RS19355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19335"
                     /product="ROK family protein"
                     /protein_id="WP_114056500.1"
                     /transl_table=11
                     /translation="MTAPPAAPPGTTAARATLAADIGGTWTRLRTGGPGAPVERLRSPS
                     RLNHPGRPVTELRADMVDMLCAAAPRGAAAALSFGAAIDHLTGTVYGSAPLWGAEAEPY
                     DLGAELRRRRPDVAWSLVNDVTAALADFVVEHARHGTRRIGYLTISSGIALRVADLDSR
                     RIPVDDRGLQGEVGHLPAMVTGAAPERTGLLCECGAPDHLASVASGPGIARVAARLGID
                     AGPGLPAWLPAALADGDPAARRLLELCVEPVANLLRTLWCLDPHLDLLGLGGGVVEGLG
                     ARYADELRRQLAAPASYADPGRDGAWLAERLVFCGPGAVDPLQGAERIGRWLPGIVR"
     gene            complement(8493..9176)
                     /locus_tag="C0216_RS19360"
                     /old_locus_tag="C0216_19340"
     CDS             complement(8493..9176)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603457.1"
                     /locus_tag="C0216_RS19360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19340"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_114056501.1"
                     /sec_met_domain="HAD_2 (E-value: 1.6e-19, bitscore: 69.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDIPTSALLFDMDGTLVDSTGLVESTWAGFCTRHGLDLAEVLAY
                     AHGRPTRETVGRFLADPPLAESETRRLVAHEESETSGITAVPGAAELLAALPPGSWAVV
                     TSAGRRLAEVRMAAAGLPLPALMVTADDVEHGKPHPEGFLRAAAALGADPASTLVFEDS
                     PAGVRAGLDSGARTIVIGGLTAHDGEAERYPDFRGFRAAASPAGPARLVLTTPEPAAAR
                     TGEGR"
     gene            complement(9231..10004)
                     /locus_tag="C0216_RS19365"
                     /old_locus_tag="C0216_19345"
     CDS             complement(9231..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603458.1"
                     /locus_tag="C0216_RS19365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19345"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_114056502.1"
                     /transl_table=11
                     /translation="MTSPDRTAPPATAVVVGGSTGIGRGIADAWAARGIETHVFSRSRP
                     AGPGGDALVWHPLDFRDAGASAEALRSGLPARADLVCYSAVYFTSRREPFLETGEADWL
                     DQFAVNVHGLARTLRVAMPLLRAAAPGLFLHVSSEVVYNAGPGRAGYAATKAAADSLVR
                     SLAQETDPAEVRFVQALPAGMVDTPGIRARRPQDFDYSGYMAPAAFAPLADRLARTRGA
                     AEHGEALVVQPDGSWSPVREGLPASQSRPLDAPRQ"
     gene            complement(10001..11248)
                     /locus_tag="C0216_RS19370"
                     /old_locus_tag="C0216_19350"
     CDS             complement(10001..11248)
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     amglyccycl: salQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385523.1"
                     /locus_tag="C0216_RS19370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19350"
                     /product="sedoheptulose 7-phosphate cyclase"
                     /protein_id="WP_114056503.1"
                     /sec_met_domain="salQ (E-value: 3.1e-186, bitscore: 617.2,
                     seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 9.1e-66, bitscore:
                     220.1, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSGTAFTQGLRQAVGDGPAWTVEAVRQVRYHVVSSDGLFEPGNT
                     ALLDGCPDVPMKRGERRLVVIDENVDVLYGAQVRDWFAAHGIEAAVVPLRADETVKQWD
                     AVSRVVDAMNDFGIDRRREPVLAIGGGVLTDIVGFAASLYRRGTPYIRIPTTLIGLVDA
                     GVGVKTGVNYERGKNRLGTYAPATATFLDRTFLRSLPYRHVSNGLAEILKMALIRSEDL
                     FRLLEEHGPAVRADRFQGTTPELAAASDAIVAEAIHLMLEELQPNLWESELERCVDYGH
                     TFSPTLEMHALPELLHGEAVVIDMALTTAMATLRGDVTAAQADRIHSAIRGLGLPAWND
                     VLHDTALLEDALRDTVRHRDGRQRLPLPMGIGRHRFVNDVTPGELRDAAALLWEHHRPA
                     EPAAAAPARVPEQVGA"
     misc_feature    complement(11310..11330)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.17"
                     /tool="antismash"
     gene            11468..11932
                     /locus_tag="C0216_RS19375"
                     /old_locus_tag="C0216_19355"
     CDS             11468..11932
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385524.1"
                     /locus_tag="C0216_RS19375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19355"
                     /product="hypothetical protein"
                     /protein_id="WP_114056504.1"
                     /transl_table=11
                     /translation="MATLAERLNAWFADAATADAVGRLREPSTAEVAQAISEDPRHNVT
                     ISRSYLTALRNGSQTNPTVSVLSAIVTYFQGRDMTLPVSVSALIDEEPPARTSELPEEW
                     AALADRQVRSIALRAGQFTPELRDQLLSIMDVLDASRKQQPSGRDGAPDS"
     gene            complement(11929..13140)
                     /locus_tag="C0216_RS19380"
                     /old_locus_tag="C0216_19360"
     CDS             complement(11929..13140)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603449.1"
                     /locus_tag="C0216_RS19380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19360"
                     /product="MAB_1171c family putative transporter"
                     /protein_id="WP_114056505.1"
                     /transl_table=11
                     /translation="MSVLNLVAIVTLLGGAAWMMPALVQHRFRDPMRLHLFLSLFLMGI
                     GNVLAQPPVLARVDEHTFPGFTKITFNVAILIGLGLMVGFLRECPLTGWRGPWPWEAVA
                     CAICLSVMTAMTAALPPHLRNHVLTSEYLVDWRVRTFYNFGNFYLFFGYAACALLAARH
                     ARKGRSLRRLSLSVISGGLTALALTCVFRFLWVNLPTLREPGRAITYADDFVFGQVATI
                     VVCAGLSLPCFVSVVQIVRERLDHRAQFLGLEELWNRLVEIHPELVLDHHRRRRNRLLV
                     SASAVYRRYVECRDGLTRLGPYLRLVAEESQGAVREDDPRTSACLVDRALRRLREQDGA
                     GGAPSSASVFVLAPGSGGRAGGTDYEEDLGALVRLSLELRTMRAAPRPAGLCGGMGGPA
                     PETV"
     gene            complement(13137..13640)
                     /locus_tag="C0216_RS19385"
                     /old_locus_tag="C0216_19365"
     CDS             complement(13137..13640)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385526.1"
                     /locus_tag="C0216_RS19385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19365"
                     /product="hypothetical protein"
                     /protein_id="WP_246042623.1"
                     /transl_table=11
                     /translation="MERSPRTRRDRLRDAQLRAHSRCLMRRLEPQLPLSVTALCERLGE
                     MRGTPISLLEWDLPADGPFGILISRRHEDVIAYQAKTTKAHQAHIILHEVGHIIAYDLA
                     GERPEQVQLRTCYSDRDERDAEIIASTIMNQAISMSRRARRYGLDEPWRPSVYNSLVLA
                     DGPT"
     gene            14280..15905
                     /locus_tag="C0216_RS35100"
                     /old_locus_tag="C0216_19375"
     CDS             14280..15905
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042897.2"
                     /locus_tag="C0216_RS35100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19375"
                     /product="DUF6777 domain-containing protein"
                     /protein_id="WP_216827100.1"
                     /transl_table=11
                     /translation="MPRIATVTGAAVVAGVLAVVFTRPDGGGGGQQTAAGEVILEPTGS
                     TGEEPFTPSTANATTALPAAAPRTAPTAARTLTSVAGSEPGLYGGSRNLASCDVEKQIR
                     YLGSDPAKNRAFASALKVEESAVPGYLRSLTPVQLRSDTRVTNHGYRNGAATGYQAVLQ
                     SGTAVLVDSHGEPKVRCACGNPLSRAVPQAGTPEQKGKSWPGYRPQNVVVVNRSETAVK
                     VFVIFDQKDRQWVSRYSGDHGKRDRKAEPPPKHWPLPPTAPPATEPPATKSPHGTRDPH
                     SPGHETRDPRSPGKETRDPQTPGRETGKPESPAPESPASERPGVRESRPPAPESPDRES
                     PSAPASPERPNLRDAETERPDAPSGESPAPEPTAPPSQERPNLRETQSEPPPPSPPRRS
                     RRPPQSRRAPLSSRPPRRAPANSSSPASSSPSSSSPATSSRTPDGTGGHGTQHRSRPAV
                     PTGRVGGGRRGADRGRVFGAARRRTPLLGGRAATGGGTALVLPAALDHAGVWSPWPCRF
                     PWDSGRGTNEGEMSGDGATSHLSW"
     misc_feature    14329..14343
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.16"
                     /tool="antismash"
     gene            15877..18312
                     /locus_tag="C0216_RS19400"
                     /old_locus_tag="C0216_19380"
     CDS             15877..18312
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557787.1"
                     /locus_tag="C0216_RS19400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19380"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_114056508.1"
                     /transl_table=11
                     /translation="MERLPTSPGDRPAGTEAPSGPAYTAAATVNEQGVVTEWSEGARRL
                     LGYEASETVGRPAAGLLADDPAESARRLAPWQDRWSGTVALRHRDGHRLEAGLLAHRWT
                     SSGGTAKWFVVSAVTGAPGLGWGEPLREWAFAQSPCFLAVFDQDLRLVRANAGMERTLS
                     LTEPEMLGLRLPEIAPDPVSDETERRMRQVLETGEPQVVDAFIRPAGASTEHGWVTSLA
                     PLRDPEGRVHAVCLAAHDRTGIEGTRQQVLVPQDDAATRIGTTLDSSRTAQELADVAVP
                     RLADFAVVDLLDPPPRGDEPSSGLSAGPVAVCRMAVQSILEGSPESRVSVGETTVYPPL
                     SPAAECLAAGRGAVYATSDPAIAAWAAEDPGASWISEYGTHSTMVVPMRADGITLGVAV
                     FGRHQHREPFQSEDLWAAEELATRAAVSIHNARRYTREHTTTMTLQRSLLPQTLPDQAA
                     LDISSRYLPAGGEAGVGGDWFDVIPLSGARVALVVGDVVGHGIRATATMGRLRTAVRTL
                     ADVDLPPDELLTYLDDLVLHLSADDGDRQGTGEAALGIGTTCLYVVYDPVTRGCTVARA
                     GHPPPAVVSPEGSVYLLDVPAGPPLGLGGLPFETVETELPEGSLLALYTDGLLQARDHD
                     IDEALDSMFGALARPASTLDTVCDRVLTAMLSHQPDDDVALLVARTRALHADQVVVWDL
                     SSDPSVVGQARRNAAEQLAAWGLEEASFVTELLVSELVTNAIRYGEPPIQLRLIHEGKT
                     LICEVSDASSTAPHMRRARTFDEGGRGLLLVAQLARRWGTRHAAVGKTIWAEQSLLGF"
     misc_feature    18329..18346
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 13.91"
                     /tool="antismash"
     misc_feature    complement(18331..18346)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            18481..18717
                     /locus_tag="C0216_RS19405"
                     /old_locus_tag="C0216_19385"
     CDS             18481..18717
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017949120.1"
                     /locus_tag="C0216_RS19405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19385"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_114056509.1"
                     /transl_table=11
                     /translation="MSLTLTTPTVHDETTAAALAPREQETLRHIAAGRTYLQTARHMGL
                     SKHTVDAYLRRIRAKLGVNSTAELTRLAIALGL"
     gene            complement(18795..19805)
                     /locus_tag="C0216_RS19410"
                     /old_locus_tag="C0216_19390"
     CDS             complement(18795..19805)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947031.1"
                     /locus_tag="C0216_RS19410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19390"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_114056510.1"
                     /sec_met_domain="Pkinase (E-value: 1.1e-48, bitscore:
                     164.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTPSSLSVYAGQPSGLIGKQIAGYRVERMLGRGGMAVVYCAKDL
                     RLDRTVALKLIAPERARDDTFRRRFTHESRVAASIEHPHIVPIFEAGETDGVLYIAMRY
                     VPGADLRALLDREGPLPVATALRIAAQVASALDAAHEHDLVHRDVKPGNILVAAGPDSE
                     HPEHVYLTDFGLTKKALSLTGFTTEGEFVGTLDYMAPEQISGRPVDGRCDQYSLACVVY
                     ETLAGGPPFEREEDAALLWAHQFDQPPPLTERRPEIPDAADEVLSRGLAKVPEDRYGSC
                     LEFVAALRAATAGAGTPVRPRHDDGQSAGTEEPPGPPPEPPEWARPVFGGTPGGT"
     gene            complement(19900..20346)
                     /locus_tag="C0216_RS19415"
                     /old_locus_tag="C0216_19395"
     CDS             complement(19900..20346)
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948553.1"
                     /locus_tag="C0216_RS19415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_19395"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_114056511.1"
                     /transl_table=11
                     /translation="MSTSSWHRPLILAAASLAFLTGTACSAHAAPPPATAGQLPPYCAA
                     GGEGGKGGEGGKGGAPGQPGEPGKPGQPGCLRFEALPDKPADQLNPADKVHIVLALLAD
                     GTDTRKKDIARQYDIPVQQLDTWKKHYLEGNWIALMNGSSLRCS"
     gene            complement(20452..20967)
                     /locus_tag="C0216_RS33560"
     CDS             complement(20452..20967)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890440.1"
                     /locus_tag="C0216_RS33560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_246042624.1"
                     /transl_table=11
                     /translation="MNRTMQNAATATATGSVRPRRRSLRLATLAASAAVVTGGVLLPAA
                     TASAAPMPAQVASALPAAGGAGGDGGAGGSGLVGGGGGAGGAGGGSVTGVGGAGGSGGD
                     GGSGLLGGAGGVGGAGGSGVIGGDGGKGGNGGFGVFQGGDGGKGGSGGFGIFGGLGGAG
                     GKGGGSIF"
ORIGIN
        1 cagggagatg ccgaagccct cgggggtggg cgggttctgc ggcagcagga agtcggtggc
       61 gagctggacg gcgaccatgc aaacgaccat ggcggcggcc cagccccaca gcgcccgctc
      121 cctgatccgc agcacgggcc cgatcaggaa ggggaagagc aggtagaaga gcagctcgct
      181 gcagagcgac cagctgggcg ggttgacgct gatgaaggtc tcgtgctgcg ggaaccagga
      241 gtggacgagg aagaggttcg gcagccaggc ggacagcggt gtcatcgctc cggcgaacag
      301 caccatggcg agcgcccaca tcacgatgtg gttggggaag atcttcagca ggcggcggcg
      361 ccagaacccg gtggcggtgt cgccgggctt ggccgaccag gtcaggacga agccgctgag
      421 gacgaagaag aacgacacgc ccatccagcc ggccttgctg aacagccagc ggaaaccctc
      481 ctcccaggcc tggtcggcga aggggttcat gggcgggtcg ctgaaggtcg cgtggaagaa
      541 gaagaccagg gcggcagcga tgaagcgcag gcccgtcagc gagggcagtt tggctctgga
      601 cggcccgggg gcggtgccgg gggcggcaat cggggacggc ggggtcatgg gcggtcggcc
      661 ctttcaggag gcgtgggtca gggagcgctg cgacggggct tcggcggggg cggccggctg
      721 cttcctccgg ggccgcgccc agcgctgcat cagggggcgc tccacgcaca gcaggagcag
      781 ccggccgagg acgagggagg cggcgaactc cgcggcgatg acggcgatcc cgacggggac
      841 ggagtacgtg cggtggtcca tcagcgtggt gcgggtgaag gacagcacga tctgctggac
      901 gaggtagaag ccgaaggatg cctcgccgag ccactgcatg gtgcggctgc gcagcccggt
      961 cggggtgccg tcggcgtcgg cgcgggcgac cgcgcagatc agcagggaga tcgggacgat
     1021 gttggtgagg gtgaggccgt acaggaacgg cacttcgagg gcggcggcgt agccggccac
     1081 gcagagcagg gcggcgggga ggacccgtac gcgggggaag gccccggcga ggacgagccg
     1141 ggcgagcagc atgccgagga cgaactcgaa catgcgcatc ggggggaagt tgtagccgaa
     1201 ccagaactgc cagacggtca cgtcggtgcc cggggcgggc gggctcgcgg gtgcgaggaa
     1261 gtcggtggcg agctgtacga gggccatgca ggcggccatg gcggcggccc agccccacag
     1321 cgcccgctcc ctgatccgca gcacgggccc gatcagcagg gggaagagca ggtagaagag
     1381 cagctcgctg cagagcgacc aggcgggggt gttgaggccc atgtggacgg ccgggtcggg
     1441 gaaccaggac tggatcagga agaggttcgg cagccacacg tgcgcgggga cggccgtgcc
     1501 ggcgaagagg acgatcgtgg cggcccaggt gacgatgtgg ttggggaaga tcttcagcag
     1561 gcggcggcgc cagaacccgg tggcggtgtc gccgggcttg gccgaccagg tcaggacgaa
     1621 gccgctgagg acgaagaaga acgacacgcc catccagccg gccttgctga acagccagcg
     1681 gaagccgtcg gcgacgtcct cgtcggcgaa ggggttcatg gagatgaaca ccagcgaggc
     1741 gtggaagaag aagaccaggg cggcggcgac gaaccgcagg cccgtcagcg aggggagcgg
     1801 gggtctggcg ggaggcacgg ggctgctggg catgggcggt gctgccttcc tcgttcggtg
     1861 ggcgctgttt caggaggccg gcgcggcggt ggcggcggtg gcggtggcgg gttcggctgc
     1921 cgcggcggtg gcggcggccc ggcgccggcc ggcgtacacg gtctgggcga tcagcagggc
     1981 tccgagggcg gtgaacgcgg cggcgccgag cgtgacggcg cgggttccga ggccctggtc
     2041 gatgagccgg ccgccggccc aggagccgag ggcggcgccg agcccgaagg cggacatgtt
     2101 ggcggtcagg gacagcgtcg gggcgtccgc cgccgcggag aggaccttcg tctggaggcc
     2161 ggggatcagg gcgaaggtgg ccatggagaa caggagcagg aagacggcgc cgccggcggc
     2221 gtacggcgcg gcggcccagt acaggaggca gacggcggcg agcgtccagg acaggcggag
     2281 tacggcccgg tccgcggacc ggtcggcgta cctgccgccg agggcgttgc cggcgacgga
     2341 gccgatgccg taggccacga ggacggccgg cacccaggcg gcggggaagc cgccgacgtc
     2401 ggtcagcagc ggcaccatgt aggtgatcag ggtgaacatg ccggccgagc acaggacggt
     2461 ggcgaggacg gtgccgacca cctgccactc cttgaagacc cgcagttcgt gcgcggcgga
     2521 ggagccggcc gtgcggccgt cgtccgggat gaccagcagg atcagggctg cggcggccag
     2581 ggcgagcacg gcgacgctgc cgaaggtggc gcgccagtgc agctgttggg cgacgagggt
     2641 gccgaggggg acgccgagca cggtcgccag gttcacgccg agctgcgtgg cggcgaccgc
     2701 ggatccctcc ttgccctcgg cggccatgcc gcccgcggtg accacgcaga cggcgaggaa
     2761 ggtgccgtgg atgacggcgg tcagcatgcg gccggcgacc agcagggcga aggtgggcgc
     2821 caggctggag aggacgttgc cggcaacgga caccagcagc agcgccacca gcaggtactt
     2881 gcggcggatc cgggtggacg ccgcggtgac gagcggtcct gcgacgacca cggtcagcgc
     2941 gtagacggtg acgagcaggc ccgcggtggg gatcgtcacc gacaggtcct cggccaggtc
     3001 gcccagcatg ccgctggggg cgagttcggc ggtgccgacg cagaagatgg ccaggatcag
     3061 tacagccata cgggaccgca tggaatgcct ctcgtgtgca gcggggcggc gggcggtgga
     3121 cgggcgcgcg ggcggtgcgc gggcaggccg ccggacttcg accggtgggg cggcgcgggc
     3181 agttcgcgct gcgcaccgcc tgtcgccgct accggtatcg gagtctctat cgaaacccaa
     3241 tgatcagctt aatggcgact tggccactat acaagcagta tgaacgatgg agggctcatg
     3301 ctgtcgtcgt cgcgagctcg ttcgcctgtg caggcggcag ctacgtgagg cgcgccgagg
     3361 gaatcggccg cctcagcagc accacggcca gcaccgccgc cgcaagcacg gcggagacgg
     3421 ccggcagcag ggccgtgggg ccgcccaaca gggcggctcc gagggccgat ccgccggcga
     3481 tgcccacctg gaagccggtg acgtacaccg aggacgcacg gtcggcgtcc cccgcggcca
     3541 gcctcatgac tcccgtctgg aagacgggcc cggccgcagc gaaggcaccg ccccacaccg
     3601 ccacggcgac ggcggccgcg gccaggcgcg ctgcgggcgg caccggtgcg aacgccagcg
     3661 cgagcagggc cactccggcc gtgaaagccg ccatggtcac ggccgccgcg cgctgcggcg
     3721 cccggtcgcc gtgccggccg atcaggtacg tcccgacggc ccccgcgaca ccgaaggccg
     3781 caagcagggc ggtgaccggt cccgcaccgc cgcccgcggc gtcggccacg atgacggcga
     3841 agtaggtgta gctgaggaag tgcgcggtca cgagggcgac cgcggtgccg cacagccgca
     3901 gcaccgcggg ccagtccacc tgcccgcgcg cgtccccccc ggccccggcc cgagcggtgt
     3961 cctccggaac cgcggcggcc gctcccggcc ggacggccca cacgagcgcg caggtgacgg
     4021 ccgccgtggc ggccgccagc agcagggcgg tggcccgcca gccgatgaga ccgccgacca
     4081 gggtcgtgcc cgggctcccg acgatcgccg cgagcgacgc gccgccgaac acggcggcgg
     4141 tggcgctccc cacctgcccg cggggcacca tggccgcggc cgccggggcg acgagcgacc
     4201 agagcacccc gtgtgtcagg gccgcggcga cccggctgac ggccatcatc gcgaacccgg
     4261 tcgaggcggc ggccagcacc tcggcggcga acagcacgac cagggaggcc gccagcgccg
     4321 tgccgcgcga catgcgcgag gcgagcgcca ccgcggggac ggtgacgacc gcggcgacca
     4381 ccgcgtatcc gctgatcagc aggccgaccc ggccctcgga gacgtcgagg tcccgggcga
     4441 tgtcgcggat cagcccgacg gggaagacct cgaaggtgac atacacgaag gtggccgcgg
     4501 cgagcaccgc cagccgggcc gcggtggcgc cggccggccg gcgcgccgcc gccgtggccg
     4561 ccgcagggct catcggcccg caccggccgc ggcggcgtcc atccgtacga ggatcttcgg
     4621 gcgggtccgc gcgccgtccg cgaggcaggc gaaggcggcg tccggtgcgg tgagcgggaa
     4681 gacgcggtcg acgagggcgt ccaggtccac ggccccttcc tcgacgaggg ccacgagccg
     4741 gtcccagtgg ccgatgccgg acaggacgcc gtggacggtg gcgtcccgga tgaccagggc
     4801 ggccgcgtcg aagccgtcga cggcgtggtg cggggtgccc agttgggcca tccggccgcc
     4861 cgcggcgacg aggcggacgg ccgcgcggac ggccgcggtg ctgccggagg cctccaccac
     4921 ggcgtcgtag cgctcctcgt cagggcccgc gggtgcggcg gaggcgcgca gtcccagccg
     4981 ccgcgccagg tcgcgggccg cgggctgcgg gtcgaagacg acggggtcgg cgccgagtgc
     5041 ccgggccacc tgggcggccg cgagcccgag cgtgccgccg ccgaggaccg cgacgcggtc
     5101 gcgggcgccg acggcgagcc ggtcgatggc gtggacggcg gcggcggtcg gctccagcag
     5161 ggcccccgcc tcgtcggaga gggagtcggg gatgcgggtc agggtgtccg cgggcgcggt
     5221 gatcagttcg gcgccggctc ccgggcagtc gccgagcacg ccgatctcgc tgcggtcggg
     5281 gcagtagcgg atgcggccgg cgcggcagtg cgggcaggtg ccgcagggcc ggaagttgtg
     5341 cccggagacg cgctgtccgg ccagctccgg gtcggcgccg gggccgaggc cgacgacggt
     5401 gccgatccac tcgtggccgg ggacgaaggg gtagctcttc cagccgtcgc ggaggtagtt
     5461 gctcgtgccg tcgtagaaac cgaggtcggt tccgcacagg ccgagcaggg ccacccggac
     5521 cagcacctcc ccggggccgg gtgcgggcgg ctcgacctcg gcgacggaca ccgcgcgggg
     5581 gccggtgagc tgaatggctt tcatcgtgga tcctcgggtc gggtgggttc ggccgcggcg
     5641 cggcacagtc tgatgtcctc gggcaggcgg gcggcccccg cgccccggta gtcgttctcc
     5701 acgagcacgg agcgggccgc ggaccgtgcc agcagtgcgg gcagttccgc gaaggccgag
     5761 ccgggggccg ccgggccggc cgcggggtcc ttcacgtgca ggtcgggcag gagcagcccg
     5821 gccgccccgg cctcgcgggc gaaggccagg gggtcctcgc ctgcgtcgcg gaggttgccg
     5881 gtgtcgagca ccaggcgcag ggccgggtgg tcgacgcggc gggccagggc gaggaggtcg
     5941 cggtggccga ggggggactc gtaggcgagg acgaggcccg ccgacgcggc gcgttcgcac
     6001 agcgtgcgca gggcatcggc ggtgccggcg cgcagtcctg cggtggcggg cgtgctgcgc
     6061 cggaagccgg ggacgtgcag caccccggcg ccgaggcgga gcgcgcagtc ctgggcgcgc
     6121 tccaggaggg cgagcgccgc cgggttggcg gtgccccgct cctcggcgag gccgaggtcg
     6181 ttgacgtggt tgacggcgag gaccggcacc gggatgtccc cggcgatcgc cgcggcttcg
     6241 cgcagtgcgg cgggttcgcc gagcggggtg ccgcggtggg cgccgccgta gtccaggtgc
     6301 agcaggtccg ccccggcggc gagtgcggtg cgggcggcgc ggcgccggtc ggtgccgatc
     6361 cgccactggg gcgcggcgac ggccggggtc atgccggccc gccgatcagg atggcggcct
     6421 tgaggacccg ccggccgcct gcggaccggt cgtccgcgtc gaggacggag ttgacgaggc
     6481 cggcggcgcc ttccaggtcc acggtgtggg tgaggacgcc ggcccccgcc ggtgcggagc
     6541 cgctggccag gaggaggtcg aaggcctgcc gcaggtgctc tccgcccacc ccgcggtgcc
     6601 cgtacagcag cagggggccg gccgggcggt cgaggcggtg cacccggggc ggccagggcc
     6661 ggcccccgca gttgtccgca cgcagcgccg cgacgtcgac gggcccggcg gtcagtggga
     6721 cggggccttc cggcaggccg gcgtgcacgt ccacgaggag ggtgccccgg acgtggcggt
     6781 cgagggcggc cagcgcctgc cgcgttccgg tgcgcggggt ggcgatcacg gcggcgaccg
     6841 gccccgggag cccggccagc atgtgcggaa ggccggggtc gagcgggtgg acggcgtcgg
     6901 cgccgtgccc cacgagcagg gtgcgcaggc cggggagttc gcgccgccag gcctcgcggg
     6961 cgagccggcc gacggtgccg tcgccccaga cggccagggc ggcgggccgc accgtgtgcc
     7021 gggcgatccg cagcccgtac aggacggacg cgaggggctc ggcgagggcg gcggcccggg
     7081 gcgctgcggc gccgtccggg acgggaagga ccagcccggc gcggacggcg gcggcgggga
     7141 tgcgggtgcg ctcggcccac aggccgggca ggttgtgccc gaggaggaag gacgggtcgc
     7201 cggggtgggt ggggttgacg gtgacgagcc ggccggcggg cagcccggag tcgccgggct
     7261 cgacgacgcg ggccacgccc tcgtggccgg ggacggggct ggggtcgcgg cgcaggccgc
     7321 gcaggatctg ccagtcggtg ccgcagatgc cggcggtcag cggggccagc agcatgtcgc
     7381 cgggcgcgag gggaggcgtc ggcacctcgg ccacttcgac gcgggtacgg ccgcgggcgt
     7441 ccgcgggcag gcgccgcagc gcgcggtggg tcgccgcgct catcggacga tccccggcag
     7501 ccagcgcccg atccgctcgg cgccctggag cgggtccacg gcgccgggcc cgcagaagac
     7561 gagccgctcg gcgagccagg cgccgtccct gcccgggtcg gcgtacgagg cgggggcggc
     7621 gagttggcgg cgcagctcgt cggcgtagcg ggcgccgagc ccttcgacga ctcccccgcc
     7681 gaggccgagc aggtcgaggt gggggtctag gcaccacagg gtgcgcagca ggttcgcgac
     7741 gggttcgacg cagagttcga ggaggcggcg cgcggcgggg tcgccgtcgg cgagtgccgc
     7801 gggcagccag gcggggaggc cggggcccgc gtcgatgccg aggcgggcgg cgacgcgggc
     7861 gatgccgggt ccggaggcga cggaggcgag gtggtcgggt gccccgcatt cgcacagcag
     7921 gcccgtccgc tccggcgcag cgccggtgac catggcgggg aggtggccga cctcgccctg
     7981 gaggccgcgg tcgtcgacgg gtatccggcg gctgtccagg tcggcgacgc gcagggcgat
     8041 gccgctgctg atcgtcaggt agccgatgcg gcgggtgccg tgccgggcgt gttcgacgac
     8101 gaagtcggcg agggcggcgg tgacgtcgtt gacgaggctc caggcgacgt cggggcggcg
     8161 gcggcgcagt tccgccccga ggtcgtaggg ctcggcctcg gctccccaca ggggggccga
     8221 tccgtagacg gtgccggtga ggtggtcgat ggccgccccg aaggagagtg cggcggcggc
     8281 gcctcggggg gcggccgcgc acagcatgtc gaccatgtcg gcgcggagtt cggtgacggg
     8341 ccggccgggg tggttgagcc ggctcgggga gcggagccgt tcgacggggg ctccgggccc
     8401 gccggtccgc agccgcgtcc aggtgccgcc gatgtcggcc gcgagggtcg cgcgtgcggc
     8461 cgtggtcccg gggggcgcag ccgggggcgc ggtcaccggc cctcccccgt acgggcggcg
     8521 gccggctcgg gggtggtcag gaccaggcgg gcggggccgg ccggggaggc ggcggcccgg
     8581 aagccgcgga agtctgggta ccgctcggct tcgccgtcgt gggcggtgag gccgccgatg
     8641 acgatggtgc gtgcgccgct gtccaggccg gcccggactc cggcgggcga gtcctcgaag
     8701 acgagggtgg aggccgggtc cgccccgagg gctgcggcgg cgcgcaggaa gccctcgggg
     8761 tggggcttgc cgtgctcgac gtcgtccgcc gtgaccatga gcgcgggcag cggcagtccg
     8821 gcggcggcca tgcggacctc ggccagcctg cggccggccg aggtcacgac ggcccaggag
     8881 ccgggcggca gggcggcgag gagttcggcg gcgcccggga cggcggtgat gccggaggtc
     8941 tcggactcct cgtgcgcgac gagccgccgc gtctcggatt cggcgagcgg cgggtcggcg
     9001 aggaagcggc cgacggtctc ccgggtgggg cggccgtggg cgtaggccag tacctcggcg
     9061 aggtccagtc cgtggcgtgt gcagaagccg gcccaggtgg actccacgag tccggtcgag
     9121 tcgaccagcg tgccgtccat gtcgaacagc agcgccgagg tgggtatgtc tgacaagggt
     9181 cctcctgggt cgtggtcgcc gggctgcccg gccgtgctgg gggtggcgcc ctactggcgc
     9241 ggggcgtcca ggggccgcga ctgggacgcc gggagtcctt cgcggaccgg cgaccagctg
     9301 ccgtcgggct gcaccacgag tgcctcgccg tgctcggccg ctccgcgggt gcgggcgagc
     9361 cggtcggcga gcggggcgaa ggcggccggg gccatgtagc cgctgtagtc gaagtcctgg
     9421 gggcggcggg cccggatacc gggggtgtcg accatgccgg cgggcagcgc ctggacgaac
     9481 cggacctcgg cggggtcggt ctcctgcgcg agggagcgga cgagggagtc ggctgcggcc
     9541 ttggtcgcgg cgtaaccggc gcgcccgggg ccggcgttgt agaccacctc ggacgagacg
     9601 tgcaggaaca ggccgggggc ggcggcccgc agcaggggca tggcgaccct cagcgtgcgg
     9661 gccaggccgt ggacgttgac ggcgaactgg tcgagccagt cggcctcgcc ggtctccagg
     9721 aacggctcgc gccgggaggt gaagtagacg gccgagtagc agacgaggtc ggcgcgggcg
     9781 ggcaggccgg agcggagcgc ctcggcggag gcaccggcgt ccctgaagtc cagggggtgc
     9841 cagaccaggg cgtcgccgcc cgggccggcc gggcggctgc ggctgaagac gtgggtctcg
     9901 atgccgcggg cggcccaggc gtcggcgatg cctcggccga tgcccgtgga cccgccgacg
     9961 acgaccgcgg tggccggggg tgcggtgcgg tcgggggagg tcatgcgccc acctgctcgg
    10021 ggacgcgggc cggcgccgcg gcggcgggct cggcggggcg gtggtgctcc cacagcaggg
    10081 cggcggcgtc gcggagttcg ccgggggtga cgtcgttgac gaagcggtgg cggccgatgc
    10141 ccatcggcag cgggagccgc tgccggccgt cgcggtggcg gacggtgtcg cgcagcgcgt
    10201 cctccagcag ggcggtgtcg tgcaggacgt cgttccaggc gggcaggccg aggccgcgga
    10261 tcgcggagtg gatgcggtcg gcctgggcgg cggtgacgtc tccccgcagt gtggccatgg
    10321 cggtggtcag cgccatgtcg atgacgacgg cctcgccgtg gagcagctcg ggcagggcgt
    10381 gcatttccag ggtggggctg aaggtgtggc cgtagtcgac gcagcgctcc agctccgact
    10441 cccacaggtt gggctggagt tcttcgagca tgaggtggat ggcctcggcg acgatggcgt
    10501 cggaggcggc ggcgagttcc ggggtcgtgc cctggaaccg gtcggcgcgg acggccgggc
    10561 cgtgctcctc cagcaggcgg aacaggtcct cggagcggat gagggccatc ttcaggatct
    10621 cggcgaggcc gttgctgacg tgccggtacg gcaggctgcg caggaaggtc cggtcgagga
    10681 aggtcgccgt ggccggcgcg taggtgccga gccggttctt cccgcgctcg tagttgacgc
    10741 cggtcttgac gccgactccg gcgtcgacca ggccgatcag ggtggtgggg atccggatgt
    10801 agggcgttcc gcgccggtag aggctggcgg cgaagccgac gatgtcggtg agcacgccgc
    10861 cgccgatcgc gaggacgggc tcgcggcggc ggtcgatccc gaagtcgttc atcgcgtcga
    10921 cgacgcggga gacggcgtcc cactgcttga cggtctcgtc ggcgcgcagc gggacgacgg
    10981 cggcctcgat gccgtgggcg gcgaaccagt cgcgcacctg ggccccgtag agcacgtcga
    11041 cgttctcgtc gatgacgacg aggcgccgct cgccccgctt catgggcacg tcggggcacc
    11101 cgtcgagcag cgccgtgttg ccgggttcga agaggccgtc ggagctgacg acgtggtaac
    11161 gcacctggcg gacggcctcg accgtccatg ccgggccgtc gccgacggcc tggcggagcc
    11221 cctgagtgaa agcagtaccg ctgcgcatgt cccctccagt tcgagcgcca tatgacaggg
    11281 caagagaagt ttccatcggc gcctcgtcga atatagtagc agcaacgctt gcagggcgtc
    11341 atgtgtgcta tactttccgc aagcgccgct gtgacaagcg agagtgcgcg tgcacgggaa
    11401 gacggtcgag cgtgaaggcc tctgtgctca ctgacgaaac ccgacgaaag caccggaggt
    11461 cggtcgcatg gcaacgctgg cggaacgcct gaacgcatgg ttcgccgatg ccgccacggc
    11521 ggacgccgtg ggccggctgc gcgagccgtc gaccgccgag gtcgcccagg ccatctcgga
    11581 ggacccccgg cacaacgtga cgatctcccg gagctacctg acggccctcc gcaacggctc
    11641 gcagaccaac cccacggtca gcgtcctgtc ggcgatcgtg acgtacttcc agggacggga
    11701 catgaccctg cccgtctcgg tcagcgccct catcgacgag gagcctcccg cgcgcacctc
    11761 cgaactgccc gaggagtggg cggccctggc cgaccggcag gtccgctcga tcgccctgcg
    11821 cgccgggcag ttcacgccgg agctgcgcga ccagctgctc tcgatcatgg acgtgctgga
    11881 cgcctcgcgg aagcagcagc cgtccgggcg cgacggcgca ccggactcct agaccgtctc
    11941 gggcgcaggc ccgcccatgc ccccgcagag gcccgccggg cgcggcgccg cccgcatcgt
    12001 gcgcagttcg agggagagcc tgaccagggc gcccaggtcc tcctcgtagt cggtgccgcc
    12061 cgcgcggccc ccggagccgg gggcgaggac gaagacggac gccgacgacg gcgcgccgcc
    12121 cgcgccgtcc tgctcgcgga gccggcgcag ggcgcggtcc acgaggcagg ccgaggtgcg
    12181 cgggtcgtcc tcccgcaccg ccccctgcga ctcctcggcg acgagccgca ggtaggggcc
    12241 gagacgggtg agcccgtcgc ggcactccac gtaccggcgg tagaccgccg aagcgctgac
    12301 gagcaggcgg ttccgccgcc gccggtggtg gtcgaggacc agctccgggt ggatctcgac
    12361 cagccggttc cacagctcct ccaggccgag gaactgcgcg cggtggtcca gccgctcgcg
    12421 cacgatctgc acgacgctga cgaagcaggg caggctgagc cccgcgcaca ccacgatcgt
    12481 cgcgacctgg ccgaagacga agtcgtcggc gtacgtgatc gcccgacccg gctcgcgcag
    12541 agtcggcagg ttcacccaca ggaagcggaa cacgcaggtg agggcgagcg ctgtcagacc
    12601 gccggagatg acactcagcg agagccggcg cagcgagcgg cccttgcggg cgtgccgggc
    12661 ggcgagcagt gcgcaggcgg cgtacccgaa gaagaggtag aagttgccga agttgtagaa
    12721 ggtgcgcacc cgccagtcga caaggtactc cgaggtcagg acgtggttgc gcaagtgcgg
    12781 cgggagggcc gcggtcatgg cggtcatcac ggacaggcag atcgcgcagg cgacggcctc
    12841 ccagggccat ggcccccgcc agccggtcag cgggcactcc cggaggaacc cgaccatgag
    12901 gccgagaccg atcaggatgg ccacgttgaa ggtgatcttc gtgaagccgg ggaacgtgtg
    12961 ctcgtcgacc cgggcaagga ccggcggctg ggccagcacg ttcccgatcc ccatgaggaa
    13021 cagcgagagg aacaggtgca gcctcatggg gtcgcggaag cggtgctgga ccagtgcggg
    13081 catcatccag gccgccccgc cgagcagcgt gacgatggcg accaggttga gaacgctcac
    13141 gtcggcccgt cggcgaggac caggctgttg tagaccgagg gccgccacgg ctcgtcgagc
    13201 ccgtagcggc gcgcacgccg gctcatggag atggcctggt tcatgatcgt cgaggcgatg
    13261 atctcggcgt cccgctcgtc cctgtcggag tagcaggtgc gcagctgcac ctgctccggc
    13321 cgttcgcctg cgaggtcgta ggcgatgatg tggccgacct cgtgcaggat gatgtgcgcc
    13381 tggtgcgcct tggtggtctt cgcctggtag gcgatgacgt cctcgtgccg gcgcgagatc
    13441 aggatgccga acgggccgtc cgccggcagg tcccactcca gcaggctgat cggcgtcccc
    13501 cgcatctcgc cgagccgctc gcacagcgcg gtgacgctga gcggcagctg cggctccagc
    13561 cgcctcatca ggcagcggct gtgggcgcgc agttgcgcgt cgcgcagccg gtccctccgc
    13621 gtgcgcggtg atcgttccac accccgcccg aaccgaccga acacaaggcc ccctccccgt
    13681 tcgctcaccg gccggggacc cgggggcgcg acgcgtggtc gcttccgggc cggccggcca
    13741 cggggcaaat ctacgccacc tgcacggccc cggacgctcc gggagaggaa gatcacgatg
    13801 ggtcagcggc ggggaatgcg ctggtcaggc tcgttccgcg cgctcggacg ggtggtggtc
    13861 ggtgaagtgc gcggcggggc gggacaggtc gcgccttgat cggttgggga ttccgcggga
    13921 ccggggcgca caatgtgtgc tagcagacaa acccacacca agggcagggc aggcggcacg
    13981 ggtgcggccg ggacgaccgg tcgggcgcgc ggcgccggtg ccggtgccgg gtgggaggga
    14041 aaacggtgag ttccgaaccg cgctccgagc gccccaccgg cccgccctca ggcccgctct
    14101 ccggacgccc gtccggcgat gcgacgaggc cgatcccccc gcctcccccg ccgacggccg
    14161 gcggcggggg aggcgggggc gggggcgggc ccgatgagcc gggagggccc gggggtccgg
    14221 gcggtcccgg cggtccggag cagcagccgg gcggcggcgg gcggccgtgg tggcgctcgg
    14281 tgccgcggat cgcgaccgtg accggggcgg cggtggtcgc cggggtcctg gcggtcgtct
    14341 tcacccggcc cgacggcggg ggcggcggac agcagacggc ggcgggagag gtgatcctgg
    14401 agcccaccgg gtccaccggc gaagagccgt tcaccccgtc gaccgcgaac gcgacgaccg
    14461 cgctgccggc cgcggcgccc cgcactgccc cgacggccgc ccggaccctc acgagcgtgg
    14521 cgggctcgga gcccggcctg tacggcggca gccgaaacct cgccagctgc gacgtggaga
    14581 agcagatccg ctacctcggc tcggaccccg cgaagaacag ggccttcgcc tccgcgctga
    14641 aggtggagga gtccgccgta cccggctacc tgcgctcgct gacgcccgta cagctccgct
    14701 cggacacccg cgtcaccaac cacggctacc gcaacggcgc ggccaccggc taccaggcgg
    14761 tgctccagtc cggcacggcc gtcctggtcg acagccacgg cgagccgaag gtgcgctgcg
    14821 cctgcggcaa cccgctgagc cgcgcggtcc cgcaggccgg cacccccgag cagaagggga
    14881 agagctggcc cggttaccgg ccgcagaacg tcgtcgtggt caaccgctcg gagacggcgg
    14941 tcaaggtctt cgtcatcttc gaccagaagg accggcagtg ggtgagccgg tactcgggcg
    15001 accacggcaa gcgcgacagg aaggcggagc cgccgccgaa gcactggccg ctgcctccga
    15061 cggccccgcc ggcgaccgag ccgcccgcga cgaagtcccc ccacgggacc cgcgaccccc
    15121 actcccccgg gcacgagacc cgcgacccgc gctcgccggg gaaggagacc cgcgacccgc
    15181 agaccccggg ccgcgagacc gggaagcccg agagcccggc cccggagtcg ccggcctccg
    15241 agcgccccgg tgtacgggag agccggccgc ccgcgcccga gtcccccgac cgggagtcgc
    15301 cgtccgcgcc cgcgtcgccc gagcgtccga acctccggga cgccgagacc gagcgcccgg
    15361 acgcgccctc cggggagagc cccgcaccgg agccgaccgc acccccctcg caggagcgcc
    15421 cgaacctgcg ggagacgcag tccgagcccc cgcccccgag ccctccccgg cgcagccgtc
    15481 ggcccccgca gagcaggaga gccccgctca gcagtcgccc gccccggagg gccccggcga
    15541 acagcagcag cccggcgagc agcagcccga gcagcagcag cccggcgacc agcagcagaa
    15601 ctcctgacgg caccgggggc cacggcacgc agcaccgcag tcggccggcg gtcccgacag
    15661 gccgtgtcgg aggaggccgc cgcggggcgg accggggccg cgtcttcgga gccgcccggc
    15721 gccgcacccc gctgctcggc ggccgggcgg cgaccggcgg tggcactgcg ttggtgctcc
    15781 ctgccgcgct ggatcatgct ggtgtgtgga gcccctggcc gtgcaggttc ccgtgggaca
    15841 gcggcagggg aacgaacgag ggcgagatga gcggcgatgg agcgacttcc cacctctcct
    15901 ggtgaccggc ctgcgggtac ggaggcgccg tccgggccgg cgtacacggc cgcggcgacc
    15961 gtcaacgagc agggcgtcgt caccgagtgg agcgagggcg cgcgccggct gctcggctac
    16021 gaggcctccg agacggtggg ccggccggcc gccgggctgc tcgcggacga tccggccgag
    16081 tcggcgcgga ggttggcgcc ctggcaggac cggtggagcg gcaccgtcgc gctgcggcac
    16141 cgggacggcc accggctgga ggcggggctg ctcgcgcacc gctggacctc gagcggcgga
    16201 acggcgaagt ggttcgtggt gtccgcagtg acgggcgcgc cgggcctcgg ctggggcgag
    16261 ccgctgcggg agtgggcctt cgcccagtcg ccctgcttcc tcgcggtctt cgaccaggac
    16321 ctgcggctgg tgcgggcgaa cgccggaatg gagcggaccc tgtccctgac ggagccggag
    16381 atgctgggac tgcgcctgcc ggagatcgcg ccggacccgg tgagcgacga gacggagcgg
    16441 cggatgcggc aggtgctgga gaccggggag ccgcaggtcg tggacgcctt catccggccg
    16501 gccggggcga gcaccgagca cggctgggtg acctcgctgg ccccgctgcg ggacccggag
    16561 ggccgcgtgc acgccgtgtg cctcgccgcg cacgacagga cgggcatcga ggggacccgg
    16621 cagcaggtgc tcgtcccgca ggacgacgcc gccacgcgca tcggcaccac gctggacagc
    16681 tcgcgcacgg cgcaggagct ggccgacgtc gcggtgcccc ggctcgcgga cttcgccgtc
    16741 gtcgacctgc tggacccccc gccgcgcggc gacgagccgt cgtccgggct gtcggccggg
    16801 ccggtcgcgg tgtgccggat ggcggtgcag tcgatcctgg agggcagccc ggagtcacgg
    16861 gtgtcggtcg gggagacgac ggtgtacccg ccgctgtccc cggcggccga gtgcctggcg
    16921 gccgggcgcg gcgccgtgta cgcgacgtcg gacccggcga tcgccgcgtg ggcggccgag
    16981 gaccccggcg cgtcctggat cagcgagtac gggacgcact cgacgatggt cgtcccgatg
    17041 cgcgccgacg ggatcacgct gggcgtggcg gtgttcggcc ggcaccagca ccgggagccg
    17101 ttccagtcgg aggacctgtg ggcggccgag gagctggcga cgcgcgccgc cgtcagcatc
    17161 cacaacgcgc gccggtacac ccgcgagcac acgaccacga tgacactcca gcgcagcctg
    17221 ctcccgcaga cgctgccgga ccaggccgcc ctggacatct cctcgcgcta cctgcccgcc
    17281 ggcggggagg ccggggtggg cggcgactgg ttcgacgtga tcccgctgtc cggggcgcgt
    17341 gtcgccctgg tggtgggcga cgtcgtgggg cacggcatcc gggccacggc gacgatgggc
    17401 cggctgcgga ccgcggtgcg caccctggcc gacgtggacc tgccgcccga cgagctgctg
    17461 acctacctcg acgacctcgt cctgcacctg tccgccgacg acggcgaccg gcagggcacc
    17521 ggggaggcgg cgctcggcat cggcaccacc tgcctgtacg tggtctacga cccggtgacc
    17581 cggggctgca ccgtcgcccg ggccgggcac ccgccgccgg ccgtggtctc gccggagggg
    17641 tcggtgtacc tgctggacgt gccggccggg ccgccgctgg gcctgggcgg cctgccgttc
    17701 gagacggtgg agacggagct gccggagggc agcctgctcg ccctctacac cgacggcctg
    17761 ctccaggcgc gcgaccacga catcgacgag gcgctggaca gcatgttcgg ggcgctcgcc
    17821 cggccggcct cgacgctgga cacggtgtgc gacagggtgc tgacggcgat gctctcgcac
    17881 cagcccgacg acgacgtggc gctgctcgtg gcgcggacgc gggcgctgca cgcggaccag
    17941 gtcgtggtgt gggacctctc ctccgatccg tccgtggtgg ggcaggcccg ccgcaacgcc
    18001 gccgagcagc tggcggcgtg ggggctggag gaggcgtcgt tcgtcacgga gctgctggtc
    18061 agcgagctgg tgacgaacgc gatccggtac ggggagccgc cgatccagct gcgcctgatc
    18121 cacgagggga agacgctgat ctgcgaggtc tccgacgcga gcagcacggc cccgcacatg
    18181 cggcgggccc ggaccttcga cgagggcggg cggggtctgc tgctggtcgc gcagctcgcc
    18241 cggcgctggg gcacgcggca cgccgcggtg ggcaagacga tctgggcgga gcagtccctc
    18301 ctggggttct gaccagcgga cggggcgcct gtgacgcgcc tgtgacagtc gggggacacg
    18361 gcggtgaagg tcccgagcca ggcttttcca taagagacaa aagggacatt cagtaacgag
    18421 tccctctgct tccgaggacg tgagcagtga cggccgagcc cattcggcgg aggaaaagcc
    18481 atgagcctca cactcaccac ccccaccgtg cacgacgaga ccaccgccgc cgccctggcc
    18541 ccgcgtgagc aggagacgct gcggcacatc gccgccgggc gcacctacct ccagaccgcc
    18601 cgccacatgg gcctctccaa gcacacggtc gacgcctacc tgcggcggat ccgcgccaag
    18661 ctgggcgtca acagcacggc ggagctgacc cggctggcca tcgccctggg gctgtgacgg
    18721 cggggcgagg gcggcccgcc ggctgaagcg ggaaggggtg aggaggaggg ggcgggggcg
    18781 ggggcggggt aaggtcacgt ccctccgggc gtgccgccga agaccggccg ggcccactcc
    18841 ggcggctccg gcggcggccc ggggggctct tccgttccgg cggactgccc gtcatcgtgc
    18901 cggggccgta cgggcgtccc ggcgccggcg gtggcggcgc gcagggccgc gacgaactcc
    18961 aggcacgacc cgtaccggtc ctcgggcacc ttcgcgagcc ccctggacag cacctcgtcg
    19021 gcggcgtccg ggatctccgg ccgccgctcc gtcagcggcg gcggctggtc gaactggtgg
    19081 gcccacagca gtgcggcgtc ctcctcgcgc tcgaacggcg gcccgcccgc gagggtttcg
    19141 tagacgacgc aggcgaggct gtactggtcg caccggccgt ccacaggccg tcccgagatc
    19201 tgctccggcg ccatgtagtc gagcgtcccg acgaactccc cctccgtcgt gaagccggtg
    19261 agcgacagcg ccttcttcgt caggccgaag tccgtcaggt agacgtgctc ggggtgctcg
    19321 ctgtcggggc ctgcggcgac caggatgttg cccggcttga cgtcccggtg caccaggtcg
    19381 tgctcgtggg cggcgtcgag cgccgacgcc acctgggcgg cgatgcgcag ggccgtcgcg
    19441 acgggcagcg gcccctcccg gtccagcagg gcccgcaggt cggcccccgg gacgtacctc
    19501 atggcgatgt acaggacgcc gtccgtctcg ccggcctcga agatcggcac gatgtgcggg
    19561 tgctcgatcg acgccgccac gcgcgactcg tgcgtgaacc ggcgccggaa ggtgtcgtcc
    19621 cgggcgcgct cgggggcgat cagcttgagc gcgaccgtgc ggtccaggcg caggtccttg
    19681 gcgcagtaga cgaccgccat gccgccgcgg ccgagcatcc gctcgacccg gtagccggcg
    19741 atctgcttcc cgatcaggcc ggagggctga cccgcgtaca cgctcaggct cgacggcgtg
    19801 cccatacgga agagtctatg cggcacctgt cgggggtgcc cccgcgcgcg ggggcgcccc
    19861 ggccggtggg ggccggggcg cctgcatgag gcggctcctt caggagcagc ggaggctgct
    19921 gccgttcatc agggcgatcc agttgccttc gaggtagtgc ttcttccatg tgtcgagctg
    19981 ctggacgggg atgtcgtact gccgggcgat gtccttcttg cgggtgtcgg tgccgtcggc
    20041 gaggagggcc aagacgatgt ggaccttgtc ggcggggttg agctggtcgg cgggcttgtc
    20101 ggggagggct tcgaagcgga ggcagccggg ctgtccgggc ttgccgggct cgccgggctg
    20161 tccgggggcg ccgcccttgc cgccttcgcc ccccttgccg ccttcgccgc cggcggcgca
    20221 gtacgggggg agctgtccgg cggtggcggg gggcggggcg gcgtgggcgg agcaggccgt
    20281 gccggtgagg aaggccaggg aggccgccgc gaggatgagg ggacggtgcc aggagctggt
    20341 ggacatgggg ttctccgcct cggggaaacg ggtgggtggg tgggggtgga gcggggtgga
    20401 ggccggcggc ctccaccccg cggatcgggt caggctcggt tcgggcgcgg gtcagaagat
    20461 gctgccgcct cccttgccgc cggcgccgcc gaggccgccg aagatgccga agccgccgga
    20521 gccgcccttg ccgccgtcgc cgccctggaa gacaccgaag ccgccgttgc cgcccttgcc
    20581 gccgtcgccg ccaatgacgc cgctgccgcc cgcaccgccg acgccgccgg cgccgccgag
    20641 gaggccgctg ccgccgtcgc cgccgctgcc gcccgcaccg ccgacgccgg tgacgctgcc
    20701 gccgccggcg ccgccggcgc cgccaccgcc gccgaccagg ccggaccctc cggccccgcc
    20761 gtcgcctccg gcgcctccgg cggccgggag cgcggacgcc acctgggcgg gcatcggggc
    20821 ggccgaagcg gtggccgcgg gcaggaggac cccgccggtg acgaccgcgg ccgaggcggc
    20881 cagcgtcgcg agacggaggc tgcgccgcct ggggcgcacg gagccggtgg cggtggcggt
    20941 ggcggcgttc tgcatggtgc ggttcatggg attctcctgc cgtgttccgg ggatgggtgc
    21001 tctctcggtg cggcccttgc ggggaatcag ggagggtccc ggtccttggg gggcttccct
    21061 cgctccggtg ggggcgcaca accagtaggc ccgagacgcc ccgccccgga cacgttccgg
    21121 aaactcgggg cttgacagcc cgggaagggc cccgctcgac gaaaccgcac tgcggtgcgg
    21181 ggcataccgg tccggccgcc gggcagccgc agcgtatgac cgcactcgtc ctgctgcccg
    21241 gggtctac
//
