LOCUS       NZ_CP030862            29609 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces globosus strain LZH-48 chromosome, complete genome.
ACCESSION   NZ_CP030862
VERSION     NZ_CP030862.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces globosus
  ORGANISM  Streptomyces globosus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6863360)
  AUTHORS   Ran,K., Li,Z., Wei,S. and Dong,R.
  TITLE     Draft genome Sequence of streptomyces globosus LZH-48
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6863360)
  AUTHORS   Ran,K., Li,Z., Wei,S. and Dong,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2018) Institute of Biophysics, Dezhou University,
            566 DaXuexi RD, Dezhou, Shandong 253023, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Portal v. version 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003325375.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:22:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,671
            CDSs (total)                      :: 6,576
            Genes (coding)                    :: 6,458
            CDSs (with protein)               :: 6,458
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 41 of 118
            Pseudo Genes (incomplete)         :: 101 of 118
            Pseudo Genes (internal stop)      :: 11 of 118
            Pseudo Genes (multiple problems)  :: 32 of 118
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:39:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3866326
            Orig. end                         :: 3895935
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030862.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..29609
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="23"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..29609
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29609
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:19609](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..19609
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            455..1312
                     /locus_tag="C0216_RS16970"
                     /old_locus_tag="C0216_16945"
     CDS             455..1312
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122836.1"
                     /locus_tag="C0216_RS16970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16945"
                     /product="DUF364 domain-containing protein"
                     /protein_id="WP_114056103.1"
                     /transl_table=11
                     /translation="MTRIDTVRPADSVRTVDALAEEVLAGGHGPLPSGLTATSVFWIHH
                     GTRLAGGDTTYLNQYVLVRVGGAFGGCAFEAGEIDPSLCREHSGAPLDVLLREAPRPLR
                     VAALDAYLAGADPHRAAAAAGRAEPVVLPAGAPEARAAARDAATAGLLDTAPGARVGLI
                     GVVNPLVAAIRERGGVPLPCDFNLKATQWGDPVTADMHEVLDAADAVVCTGMTLGNGSF
                     DTVLRRCRDRGIPLVVYAQSGSAVARAFLGSGVTALSAEPFPFSQFSGEETVLYRYRAA
                     VGGA"
     gene            1309..2340
                     /locus_tag="C0216_RS16975"
                     /old_locus_tag="C0216_16950"
     CDS             1309..2340
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962135.1"
                     /locus_tag="C0216_RS16975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16950"
                     /product="GHMP kinase"
                     /protein_id="WP_114056104.1"
                     /transl_table=11
                     /translation="MSPRSTGATGRGQAPCHHGEILQGVFRDGSGRPCPGLVTLPMAGP
                     GSSAVFTIRPGTDPQAPTVAPAGRTNAARAAALAVAECARRAGLPPCGGELRLAGDIPA
                     GLGMGSSTSDVIAAVRAVADAYGTRLPAGAVARIAARAAGPACDPLVPDGRPVLFAQRE
                     GRVLEVLGTALPPLLVVGCDLGGGAPADTLALPVREAGEADVRAWERLRALLRRAVAAQ
                     DARLLGAVATARARRGERVVGHPEFEALAAVARRVGAVGVQIAHSGAVAGVLFDAGRAA
                     ALGLPYQVRGCLDALEAHGIPAARIFTTPGVRARACASFSPSHPAAELLWTSTSRSRQA
                     TRT"
     gene            2298..2537
                     /locus_tag="C0216_RS16980"
                     /old_locus_tag="C0216_16955"
     CDS             2298..2537
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS16980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C0216_16955"
                     /product="hypothetical protein"
                     /protein_id="WP_114056105.1"
                     /transl_table=11
                     /translation="MDQHIAESTGHPDLMRLEDRLVCLRFETITSVGRGTSAGAVDVPG
                     GDPDVLPATAPAAGPARRTHAWRVSAAPGRGYDD"
     gene            2563..3165
                     /locus_tag="C0216_RS16985"
                     /old_locus_tag="C0216_16960"
     CDS             2563..3165
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956769.1"
                     /locus_tag="C0216_RS16985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16960"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_114056106.1"
                     /transl_table=11
                     /translation="MAPRRVDRAARREEILAAAVRVFARRGFAASRIEDVAAEAGIGKG
                     SVYLYFSDRDELLEAAFAALAARSAALIEEALAGTGDPAERLEHLVRSVVAVLLGERDL
                     ARVLLDVWSVGRGGRPPVDMAGFYREYRGAIAMLLADAADSGAGPTVEPVAHAAVLVGA
                     IEGCVLQWLFDSSLDLAGLVDPLLQLLIPARAKGRNP"
     gene            3162..3686
                     /locus_tag="C0216_RS16990"
                     /old_locus_tag="C0216_16965"
     CDS             3162..3686
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00026.1"
                     /locus_tag="C0216_RS16990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16965"
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_216827092.1"
                     /transl_table=11
                     /translation="MINPLKGGPPRTALRRAVLRAPIRLYRIGLGGLLGHRMLLLTHTG
                     RVSGRPRQVVVEVLAPGGRPGSYLIASGYGERSQWLRNVLAEPCVRYQVGRRKFEGTAV
                     PLPPEESGRQLAEYARRHPRLAAKLMQALGHNPQSRADFEALGADRRNGVPLVEVSPHH
                     GTAAGGPALPG"
     gene            complement(4045..4341)
                     /locus_tag="C0216_RS16995"
                     /old_locus_tag="C0216_16970"
     CDS             complement(4045..4341)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125351.1"
                     /locus_tag="C0216_RS16995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16970"
                     /product="hypothetical protein"
                     /protein_id="WP_246042580.1"
                     /transl_table=11
                     /translation="MTRRTRLRLPAQRTPASLAAAALTAVSAACAVAAAAAAPALAGES
                     LITVIDNSHADSIVEVDRSANLQNGSGTSGSDHDGSAVDVLQALVASAPAPLP"
     gene            complement(4338..5198)
                     /locus_tag="C0216_RS17000"
                     /old_locus_tag="C0216_16975"
     CDS             complement(4338..5198)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571540.1"
                     /locus_tag="C0216_RS17000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16975"
                     /product="isocitrate lyase/PEP mutase family protein"
                     /protein_id="WP_114056107.1"
                     /sec_met_domain="PEP_mutase (E-value: 1.1e-32, bitscore:
                     111.9, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYGSKLRARVARPGTTPLIGVYDMYSASIAADHYDGMFVSGFGF
                     AASYYGLPDIGFIAWPDMLSFVQRLRGAFPDHDLLVDIDDGYVDPEVACHVVESLERIG
                     ASGIILEDQRRPRRCGHADGKQVLPLAEYLDKLNMVLATRRDLVVVARTDATEEADILR
                     RAEALAATDADVVLVDGVRSVEWIRRIREVVAGKPLLFNQIAGGKSPRLSLGELTELGV
                     DIAIYSTPCLFAAHRAMHDALTELKLSDGRLPEPAAAGGIGVRESTSLLARNIARQRIL
                     EGAGA"
     misc_feature    5190..5201
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            5580..>5903
                     /locus_tag="C0216_RS35225"
                     /pseudo=""
     CDS             5580..>5903
                     /GO_function="GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014375.4"
                     /locus_tag="C0216_RS35225"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on a
                     cobalamin-like analog.; incomplete; partial in the middle
                     of a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="cobalamin-dependent protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTLKLLLANAPNPTANRNASNYACHPHIGIVQLATATRDALGDRV
                     EIRVVDGGISNTAAVQRAVRDFAPDLAGISALTPTYSEALEIASTAKACGAQVVLGDDH
                     AIFF"
     misc_feature    complement(6051..6064)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.45"
                     /tool="antismash"
     gene            6274..>6405
                     /locus_tag="C0216_RS35230"
                     /pseudo=""
     CDS             6274..>6405
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="C0216_RS35230"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVRANVGLDAADPEMLEAQRKNRTTGETNLEASRMLNKAGISVH"
     gene            6850..7530
                     /gene="leuE"
                     /locus_tag="C0216_RS17010"
                     /old_locus_tag="C0216_16985"
     CDS             6850..7530
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="leuE"
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088765.1"
                     /locus_tag="C0216_RS17010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16985"
                     /product="leucine efflux protein LeuE"
                     /protein_id="WP_114058724.1"
                     /transl_table=11
                     /translation="MLGVDNLLTYTVGALLIILLPGPSSLFTLSVAARLGVRAGYRAAA
                     GVFLGETLLMAATAAGLASLLQTNDLLFAIVKYAGAGYLTWIAVGMIRAAWTMWRRPGR
                     SAGADPEGVQARADAGAGTAAAGARLFRRSLVITVLNPKAILFFISFFVQFVDPGYPHP
                     ALSFGLLALVYQLISIAYVTALILGGTYLAAQFRRRRRLSAGLTTGAGALFLGFAAKLA
                     TAGN"
     gene            complement(7572..8672)
                     /locus_tag="C0216_RS17015"
                     /old_locus_tag="C0216_16990"
     CDS             complement(7572..8672)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884582.1"
                     /locus_tag="C0216_RS17015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16990"
                     /product="DNA alkylation repair protein"
                     /protein_id="WP_114056108.1"
                     /transl_table=11
                     /translation="MPTADELLSARTVQDLARRLAAAAGPRSAPALLACASALDGLTFS
                     GRVAAVRDAALDDLPADWGAFEASVRAALADPGFAGWMTFPVGEAVAVRGLASGPAAFE
                     PALALLRDLTPRLTAESAVRPFLRADRDRALAVMGPWVEDPDPHVRRLVSEGTRPRLPW
                     APQLPESIADPRPALPLLNALYRDDSDYVRRSVANHLNDISRDHPELAVETAGRWLAAP
                     AATTGRVARHGLRTLVKAGRADAMSVLGHAPDAPVTVRGPVIATARVAVGEHLVFEYAL
                     TNDADTPAELVLDYVVHHVKANGRRTPKVFKLATRTLAPGETLAGTRRHSFKPLTTRRY
                     FSGEHLVQLQVNGRLRGEAAFRLDAG"
     misc_feature    complement(9264..9279)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.74"
                     /tool="antismash"
     misc_feature    9265..9278
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.97"
                     /tool="antismash"
     misc_feature    9311..9325
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: strong, score: 27.49"
                     /tool="antismash"
     gene            9451..9642
                     /locus_tag="C0216_RS17020"
                     /old_locus_tag="C0216_16995"
     CDS             9451..9642
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010472150.1"
                     /locus_tag="C0216_RS17020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16995"
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_114056109.1"
                     /transl_table=11
                     /translation="MPESIAGPAPEGLDLDLDLDLSDLAITALRDTPALPESGASYGSC
                     SCQGSSSCAQPHTDTPIG"
     gene            9704..9895
                     /locus_tag="C0216_RS17025"
                     /old_locus_tag="C0216_17000"
     CDS             9704..9895
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010472150.1"
                     /locus_tag="C0216_RS17025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17000"
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_114056110.1"
                     /transl_table=11
                     /translation="MTDPTEGVLALDDLDLDLDLGELTVTALRDSVALPETGASGGVSS
                     SSCGSSSCAQPRLPELPY"
     gene            10001..12799
                     /locus_tag="C0216_RS17030"
                     /old_locus_tag="C0216_17005"
     CDS             10001..12799
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="C0216_RS17030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17005"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_114056111.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1e-22, bitscore:
                     78.5, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHPAESATPPRAAARAARPLPQPPARTAPYALVRTTVTPHPAEP
                     EASARVRALLGGLARIAAQEEAVRAGLCDDLFASRPGHSEDFHRRVVLPLRRALHNGRA
                     PRPALLARLGDLPVRVPRLGAWLALRGERAALLAEADDAVPAALAAERSALAEVCRSPG
                     FTRAVALGSTDLLRAVSRAARDEGGRRARKEEPSVLRHALRATAKTSPLSWFTAVGWSG
                     PAPAAGPPALRAVVRENRTLVAALVSALLDEPRRRGALAHRLTSSALPAGDGRARYVRD
                     TTVFAGGRYLVTREEEVEVAAHPALAVLDGLAAQPAPPDTLAARLAPALGRPEADPAVR
                     RFLDQLADNGLLVAVDPVDPQHPQPLRALADWLRRWPEDAALADRIDLLAADTARFAHT
                     PAGERPALLADLADRWRALLADTGRPVPAGAAPLNVLSEDVLAPGRPEAPRPAPASAPA
                     APGLGPVPGRPDPSGARRPAAADPAGDAPAPAAALSGSDRAALAELTALAELFDLGHLM
                     RRAAVQRFTARYGVGGTCPAPWEFAADTAASWEDAARLAALPADAPSLPPGAAELARLR
                     ARFVRLAEAAAAAAGGPEGPPDEVVLPAADVHGLAARLPDRTAARPLGYAWFVQHAAGA
                     PPADAGGGLLCVNHVYAGWGRFTSRFLDGLPPAAARAVAGEIRRGLGEGARAAQIRPVG
                     GFNANLHPLLTDAEIGPDRLRGTIAESDVDLVHDPASDQLRLRLRATGEFLDVLYLGFL
                     APVMLPQRLAPFLCDHPEGVVDFRRLLPRSTAPAPGGQVVRTPRLRHRHVVLARRRWHL
                     PEGVLAALRADLADDRGDVPAAAAARWRALLGLPEQLFLHPVPQPPAGRAAEDFLAALR
                     APKPQPLDLGSALHLRCLAGWLARHPRGVVLEEALPAFGGRDRPARAVELVAETHRPAR
                     TG"
     gene            12879..14045
                     /locus_tag="C0216_RS17035"
                     /old_locus_tag="C0216_17010"
     CDS             12879..14045
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF025394.4"
                     /locus_tag="C0216_RS17035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17010"
                     /product="lantibiotic dehydratase C-terminal
                     domain-containing protein"
                     /protein_id="WP_114056112.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.2e-18, bitscore:
                     64.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAPAAGPDPAPPAPTALDVVVHHYEPVKAPLLRESVLPLARRAA
                     AEGLAVHVERHWLRGPHVRLRLRGAPAQVAAAAERTAGELRARAAAHPSRAGVDERELL
                     EQAAAAGRAELVPPPYGPLVPDNTVRVEPVDLDPLRALIGPDGVRLREDLMAAGLPALE
                     AGTAFLGERGDTSAARVELVVTALAAHAAAHPEGLVGGHYSFLSHLEDFLVYEDPDGRL
                     RAAFERRWEAAGGRISALVGRIAAGGATGRERAWADWSAGAWQTAEERHAAGADLAGVA
                     AEYRARAAALGDRETAARWNREVRTRYSDFHRQLHRSDPEGAMWSRADYLVYRSCTNAL
                     YRLLAVCDVRPVERYLAAHLVVRSVPGLTGHRWQARIDEVIAAVEGAR"
     gene            14042..15754
                     /locus_tag="C0216_RS17040"
                     /old_locus_tag="C0216_17015"
     CDS             14042..15754
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS17040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C0216_17015"
                     /product="hypothetical protein"
                     /protein_id="WP_114056113.1"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 2.7e-12,
                     bitscore: 45.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAGGEPFTLRLRPGVAATVLRAGLHLRGRDGSVTLEGSKALPAL
                     WELLADRLGAEPAAPAGTARRPGGLDPSDPRVASALDGLAGQLRAHGLLAELPEGGEGP
                     AAWLAASTDRPGAAAAALAAAPPVVTAADPGAPLAAALLRALHRAGARPEARTDSRLPP
                     GLVVAAAGAPPVAVAADRTAGGGFVTAPTAPERVRADAGAVAARLGGTVSASAAAAGAD
                     ALTALLAGAAAQRLLCAAAGLPDPAGADEDQRLLPGRPAVLVAEAAPPRASYHPWAAGP
                     AAASEPALPPAADLAEALRRVGALADPLLGVLDAPLPGRLPQLPAALAACRTPAGPLVA
                     GAPRADLARLTAACRAAELRLGGAAVVGAGPGHARGRALRRAALAASGRADTGPALPEE
                     EWREHPQARHWWAVLTGIAGHAQARLAVRQLGGEQAYAAVVRVPGAPAPLGRAVEATPA
                     DAAAVALLGAVTRAMAADHGPAGAAHAPFSGAEAPLAAAGTEPAAWADEGWTDVWLTGT
                     AHREAALTAALTRLTGPAPGPWLPPGGDPVAARTATVLRSCGFTVLADPKESP"
     aSDomain        14066..14326
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C0216_RS17040_Thiopeptide_F_RRE.1"
                     /evalue="1.20E-14"
                     /identifier="RREFam004.1"
                     /label="C0216_RS17040"
                     /locus_tag="C0216_RS17040"
                     /protein_end="95"
                     /protein_start="8"
                     /score="45.0"
                     /tool="antismash"
                     /translation="TLRLRPGVAATVLRAGLHLRGRDGSVTLEGSKALPALWELLADRL
                     GAEPAAPAGTARRPGGLDPSDPRVASALDGLAGQLRAHGLLA"
     gene            15751..17835
                     /locus_tag="C0216_RS17045"
                     /old_locus_tag="C0216_17020"
     CDS             15751..17835
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010472143.1"
                     /locus_tag="C0216_RS17045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17020"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_246042582.1"
                     /sec_met_domain="YcaO (E-value: 1.1e-65, bitscore: 221.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 6.7e-78, bitscore:
                     260.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGTPIPATPGAACPGAAPRAAQRDPAALPAAAPCAPLPDATALA
                     GTQHPGSAGPAAQAADRPGELPVLDVEAALAAVSGTAVVHLASWTPGSAERLSRHALAR
                     PVRLVPVREDGALTVVGPVLEPGARACLVCTEYQRLASAGGRVPWRSPRLRLGGTGTPA
                     LAEGVLLLAAGLLDEEVPPAGDHGVPSATVYVVQGSRATWSTHRVRPVGGCPVCRPLPE
                     DSPAAAELPAVPRPLPDPAELRGPNDRTGAEALRAELYDERFGPVRRLFRTEDSAFGLT
                     TAWVTDGRLLDDGGYGRAADFRSSERVALFESVERLAGMRPMGRRTALRASFAELGPDA
                     AVDPVRLGLPDPVHHGHPASRTVPYRPDLELDWVYGWSLTEGRTRAVPEHVAYWDLPDP
                     PDGAPPGARVVYESSNGCGLGNSPQEAALYGLFEVAERDAFLMAWYAGTPLPGVALPAG
                     DPLVAALAARAELLGYRLRLLDATNDLGVPAVVAVCRYEGRHPAAPRAFLAAGAHHDPR
                     VAIRSAVAEAVTNVQDAAQRPAGPGRARDPERLRPMLDRPELVVGLDDHVGLNALPEAQ
                     PRLEFLFADTGAAPWQERWPGAPAPVADLTVLLSETVARLAGGGLEVVVVAQDEPGVRD
                     RLGLHCAKVVVPGTLPMTFGHVNRRTLGLPRLLEVPYRLGRTARPLRHDELPLHPHPFP
                     "
     gene            17843..19609
                     /locus_tag="C0216_RS17050"
                     /old_locus_tag="C0216_17025"
     CDS             17843..19609
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010472142.1"
                     /locus_tag="C0216_RS17050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17025"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_114056114.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9.7e-50, bitscore:
                     168.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF00881 (E-value: 1.2e-10, bitscore: 40.2,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPQAYPPPARPAAASAPAGGWQSLHLSLHTGAADTDAFVTGALA
                     PLMDARYGPESGGAWFFIRYGEGGPHLRIRFRGPGAGPVDAARLAAELGGLAADTAPVA
                     GPWPVRHGEVHAVPYEPETERYGGPEALPVAEEVFVHATRAAVAALRALPARADRLGPA
                     MDFAHATAAALGLDELAAAGWLRRHAASWRWVAEVRPLPGAAVHTRVNSVFATQREVLA
                     RRARAVRAGAAEGGAAPWLDEWVRQVRAADAVLRAVVPAGGPGTPERADRRLWVWASQL
                     HMLFNRLGVAPDEERAVCRLAGRALLEPSGGGGPAAGPAGGGFFERGARAADYQYLERS
                     KFQVGRGQDTAVRDVPRPPAVPEGRRVEGEVPLPAAPLPPVSLGGALHGRRSARGALTG
                     PLDAAELGGVLWHAHAPSHTSRQVTADGTERKARHRPYPSAGALYSVRVRLLAWDVAGL
                     PSGTYHCAPERRSLVRLGPAPEVEAVKALSSYLALPEGDPDAVGIDAAPAVLAVHLDLG
                     LLRGRYGLRALRLGLLEAGHLAQVLQLTAGAFGLATIPLGGLQDDLAHELLGLDDLDEP
                     VQYLLPLGRPAG"
     gene            complement(19641..20381)
                     /locus_tag="C0216_RS17055"
                     /old_locus_tag="C0216_17030"
     CDS             complement(19641..20381)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0055072 - obsolete iron ion homeostasis
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200: vibriobactin
                     utilization protein ViuB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002385.1"
                     /locus_tag="C0216_RS17055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17030"
                     /product="siderophore-interacting protein"
                     /protein_id="WP_114056115.1"
                     /transl_table=11
                     /translation="MAVGKGWEGVVLKLLRGKDFTFTVTGAEQVTPHYRRVSFTDGGLL
                     AAAGGSLHPTMWVRLWFTDNGKPHQRAYTLVDPDPAAGTFSLEFALHDGVASDWARTAE
                     PGATIDATVQGTGFTAPAPAPDRLLVIGDPASLPAINSLLDAHPQTPATIWFETQHEDD
                     ADLPVRLDADRHDIRRVPRSGGGAALVERIRAELPGLAPDPQTAYVWLACDTATTRTLT
                     GYLRKELGLPKQRVNGLGYWRPAA"
     misc_feature    complement(20410..20428)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 33.2"
                     /tool="antismash"
     misc_feature    20421..20436
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.37"
                     /tool="antismash"
     misc_feature    complement(20423..20436)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.37"
                     /tool="antismash"
     gene            20549..21190
                     /locus_tag="C0216_RS17060"
                     /old_locus_tag="C0216_17035"
     CDS             20549..21190
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740583.1"
                     /locus_tag="C0216_RS17060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17035"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_114056116.1"
                     /transl_table=11
                     /translation="MRPESTALASPRADVYTETVPGFGTVRFTPVDPAADSAVLHSWVV
                     EERAQFWGMIGASRELVQEIYEDVDRRDTHHAYMVRLDDEPVALFQTYQPSEDRVSLCY
                     EVREGDIGVHLMLAPANGRPRPGFSRTLIGSLTRFTFRDPAVLRAVGEPDARNAKAVAM
                     LGRLGFVPQGEITLPEIDLPEIYLPEKRAVLAFLDRPAVLPPADGSTPTP"
     gene            21199..21807
                     /locus_tag="C0216_RS17065"
                     /old_locus_tag="C0216_17040"
     CDS             21199..21807
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014673626.1"
                     /locus_tag="C0216_RS17065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17040"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_114056117.1"
                     /transl_table=11
                     /translation="MPAAHRNATGLRPPDSRTAGGLGRIALRGVDPAADAALIHRWVSQ
                     ERARFWGMGGADRERVREVYEDLDRRDTHHAFLALLDGVPAALFQSYDCAADRVSECYP
                     VRPGDVGVHLLIGPPSGPPRPGHTAALLGAFLSYLWGLPGTRRLVADPDPANHRAVARL
                     ERTGFVRGPEVGLPGIDLPEVRIPAKRARLLFLDAPPRP"
     gene            complement(21810..22640)
                     /gene="nadE"
                     /locus_tag="C0216_RS17070"
                     /old_locus_tag="C0216_17045"
     CDS             complement(21810..22640)
                     /EC_number="6.3.1.5"
                     /GO_function="GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_function="GO:0004359 - glutaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008795 - NAD+ synthase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nadE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004938865.1"
                     /locus_tag="C0216_RS17070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17045"
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="WP_114056118.1"
                     /transl_table=11
                     /translation="MSEPASTALQQEIARDLQVTDAFDAEREIERRVAFLAGKLTASGL
                     RSLVLGISGGVDSTTAGRLCQLAVERARAAGHEAAFYAMRLPYGVQADEKDAQLALSFI
                     RPDHVLTVDVKPASDAALAAAVAAGVVFRDAHHQDFVQGNIKARQRMIAQYAVAGAYDG
                     LVVGTDHAAEAVSGFFTKFGDGAADLVPLTGLTKRRVRAVADALGAPAELVWKVPTADL
                     ETLDPGKADEDALGVTYDDIDDFLEGKPVGERAFDIIARRYRATEHKRQLPIAP"
     gene            complement(22801..23256)
                     /locus_tag="C0216_RS17075"
                     /old_locus_tag="C0216_17050"
     CDS             complement(22801..23256)
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008739436.1"
                     /locus_tag="C0216_RS17075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17050"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_114056119.1"
                     /transl_table=11
                     /translation="MTAPARRTTATASAAAVVTDGHGRVLVVNPVHNERWNLPGGHLDE
                     GELPTAALRRELREEIGLDLEVGGLLVTAWLARPGGAHVFHVFEGPQLTPEQQQRITLQ
                     ESEIGEIRFCRPEDVTADMVPPYVLPVWQAALAARRQGRPAYLELSP"
     gene            23462..24304
                     /locus_tag="C0216_RS17080"
                     /old_locus_tag="C0216_17055"
     CDS             23462..24304
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (35-184). E-value: 1.1e-22. Score:
                     71.6. Matches aSDomain: nrpspksdomains_C0216_RS17080_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016578668.1"
                     /locus_tag="C0216_RS17080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17055"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_246042583.1"
                     /transl_table=11
                     /translation="MTERERARERTDGMRPAVRETYGPADLSAVPVFAGGFINFGYWQP
                     GDLGRPLTVGDRIRSQEDLYRHVLDTVGPVEGGEVLEVGCGLAVGCALALEEYAPARIT
                     GMDIHPQQLERARRANTRALAAAGPGRFRLVRGAAEWMPFGEAEFDRVYSVEAAQHFDD
                     LEAFAAEAARVLRPGGRLAVASFFAADPAAPEPLAALLTTFADGLDIARQPADLTDALT
                     RAGLEGARAESIGPAVWPGWDHWLSAQWEPGTWPRNFLHAWERGLLDYYVVTAERPRA"
     aSDomain        23567..24013
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS17080_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.10E-22"
                     /label="C0216_RS17080_oMT.1"
                     /locus_tag="C0216_RS17080"
                     /protein_end="184"
                     /protein_start="35"
                     /score="71.6"
                     /tool="antismash"
                     /translation="GFINFGYWQPGDLGRPLTVGDRIRSQEDLYRHVLDTVGPVEGGEV
                     LEVGCGLAVGCALALEEYAPARITGMDIHPQQLERARRANTRALAAAGPGRFRLVRGAA
                     EWMPFGEAEFDRVYSVEAAQHFDDLEAFAAEAARVLRPGGRLAVA"
     gene            complement(24308..24769)
                     /locus_tag="C0216_RS17085"
                     /old_locus_tag="C0216_17060"
     CDS             complement(24308..24769)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145939.1"
                     /locus_tag="C0216_RS17085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17060"
                     /product="calmodulin-binding protein"
                     /protein_id="WP_114056120.1"
                     /transl_table=11
                     /translation="MRRILTRAGSVAAVSMLALALGQPAQAAQPAEGDTVSAAARATYF
                     EFTDGTDTFVIKLTDPAKIRQARNILSGADTEHRGVMGTVVKTPASYNKPWTYHLDPNS
                     VQFFGMAMEVCDASIAYVDEHLDEVGGALLPRSTWCPWQSKLTRELPRP"
     gene            25199..25885
                     /locus_tag="C0216_RS17090"
                     /old_locus_tag="C0216_17065"
     CDS             25199..25885
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017236416.1"
                     /locus_tag="C0216_RS17090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17065"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_246042584.1"
                     /sec_met_domain="PCMT (E-value: 4e-06, bitscore: 25.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSGVGAGGDPAGAAHAGQPVTAAELFDGLGIAYEEAFGRLPAQS
                     DAVDWLAARLAPGARVLDVGSGTGRPVAERLADAGFEVTGIDVSRVMVELARAQVPKAR
                     FEQCDVRDFAPEGGFDAVCSFFPLLMMSRAEASAALRRMAGWLVPGGYLVSATVPADVE
                     DAEVEWMGRRVRVSSCSTDAYLRLLREDCGLELLHHSVSLFLPDGGLAAPEEHLFCYAR
                     RPVDGE"
     gene            complement(26096..26503)
                     /locus_tag="C0216_RS17095"
                     /old_locus_tag="C0216_17070"
     CDS             complement(26096..26503)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019547558.1"
                     /locus_tag="C0216_RS17095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17070"
                     /product="VOC family protein"
                     /protein_id="WP_114056122.1"
                     /transl_table=11
                     /translation="MAATSQKITTFLMFEGQAEEAMAFYTSLFDDAEVLDITRYGPGEP
                     GPEGTVQHAVFSLAGQQLMCIDSPAKHDFGFTPAISLFVQCDSEAELDRLYEALLEGGA
                     ALMPLGSYGFSPKFGWVSDRFGVSWQLNLPA"
     misc_feature    complement(26644..26655)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     misc_feature    complement(26707..26722)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.69"
                     /tool="antismash"
     gene            26763..28037
                     /locus_tag="C0216_RS17100"
                     /old_locus_tag="C0216_17075"
     CDS             26763..28037
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020549437.1"
                     /locus_tag="C0216_RS17100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17075"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_246042585.1"
                     /transl_table=11
                     /translation="MSSSAFGTEDGGDGPQAAQSAPLPAPDVHAADTAPSRTDHTAFRD
                     GVMHLGGDTAAPAGAGGSAKAAAGAAARAAAAAAPPQGEGWKLSGATKWLATGYTIKFY
                     DQKSADWLGPYAKATAADLQRITNLPVKVDTKPVGWEYSRPKGEVILGVLHRPCLPPDG
                     DIMGNTGWKVVRDGSGMANLSCGFTSSSVPETVTSGHAYIDSEFFTPQGKPTAAMGETY
                     MRNHISHEIGHTLGLTHANRSMKRSDCVKGTDSGQFPVMCSPAYAYQDKRAGTYVQQFD
                     VQGFRRLAAGAGAVLPPQGKVSGIAGKCLDARGGKAANGTQIQLYTCNGSVAQSWILGK
                     DGTFRALGKCLDNARNGSANGNKIQLWDCNGSAAQRWSVNAKGQIVHVASGKVLDVKGG
                     ATANSTVVQLYTPNTGKGQLWKAPK"
     gene            complement(28060..28632)
                     /locus_tag="C0216_RS17105"
                     /old_locus_tag="C0216_17080"
     CDS             complement(28060..28632)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452886.1"
                     /locus_tag="C0216_RS17105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17080"
                     /product="hypothetical protein"
                     /protein_id="WP_246042586.1"
                     /transl_table=11
                     /translation="MHDPSLPFSDAEPPFGGDSTAGPSGPVADECFGPVDVRLDAGRGT
                     VAVAGGALPEVRLVRGGGAKPNRYAPIGTRDGGRLTLTVDGGPAGIRPARAWIPRRSYR
                     VDARAGGSRYRLVPCSATASRFLRDGRRLGEFTSRGDGSVAADWLPGAGPQPQDAAVGY
                     ALAAAFGTGGRSLGDLVVDVVDALLPG"
     gene            28773..29195
                     /locus_tag="C0216_RS17110"
                     /old_locus_tag="C0216_17085"
     CDS             28773..29195
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004991266.1"
                     /locus_tag="C0216_RS17110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_17085"
                     /product="secondary thiamine-phosphate synthase enzyme
                     YjbQ"
                     /protein_id="WP_114056124.1"
                     /transl_table=11
                     /translation="MSERFTTRVLDLTTGRTETVTDLTRHCERFLSDAAAGRDGLLNVF
                     VPHATAGIAVIETGAGSDDDLLDALRALLPADDRWRHRHGSPGHGRDHVLPAFVPPHAT
                     LPVVAGRLELGTWQSVCLVDTNKDNPQRQVRLSFLG"
ORIGIN
        1 ccctggaagg cgctgtcggg cggcgagcgg cagcgcgccc acatcgcccg cgccctggcc
       61 cagcagcccc gcgcgctgct cctcgacgag cccaccaacc acctagacgt ccggcaccgg
      121 ttggagctga tggagctgct ggccgggacc ccccagaccg tcctggtcgt cctgcacgac
      181 ctgtcgctcg ccgcccggta ctgcgaccgg ctgctgctcc tgcaccgcgg acgcctggcc
      241 gcctgcggcc cgcccgcgga cgtgctgaca gaggaacagc tcgccgaggt cttcgaggtg
      301 gacgccgtgc ccgccccgga cgccctgggc cggccctcgg tcgcctaccg cgggccgctg
      361 cggccggcgc ccccgccggc cggggcaccc gcacccgtac ccgtatcccg atccgtccct
      421 gacgagaagt gaagccgagg aacccgagga tcccatgacc cgtatcgaca ccgtccggcc
      481 cgccgactcc gtccgcaccg tggacgcgct cgccgaggag gtcctcgcgg gcgggcacgg
      541 cccgctcccg agcggcctca ccgccaccag cgtgttctgg atccaccacg gcacccggct
      601 cgccggaggc gacaccacct acctcaacca gtacgtcctg gtccgggtcg gcggcgcctt
      661 cggcggctgc gccttcgagg cgggggagat cgacccgtcg ctctgccgcg agcactccgg
      721 cgcgcccctc gacgtgctgc tgcgcgaggc gccgcgcccg ctgcgggtcg ccgccctcga
      781 cgcctacctg gccggggcgg acccgcaccg cgcggcggcg gcggccggcc gggccgagcc
      841 ggtggtcctc ccggccggcg ctccggaggc ccgggccgcc gcccgggacg cggcgacagc
      901 ggggctgctg gacaccgcgc cgggggcccg cgtcggcctc atcggcgtcg tcaacccgct
      961 cgtcgccgcc atccgcgagc gcggcggcgt accgctgccc tgcgacttca acctcaaggc
     1021 cacccagtgg ggggaccccg tcaccgccga catgcacgag gtgctggacg ccgccgacgc
     1081 ggtcgtctgc accgggatga ctctcgggaa cggctcgttc gacaccgtgc tgcggcgctg
     1141 ccgcgaccgc ggcatcccgc tggtcgtcta cgcgcagagc ggcagcgccg tcgcccgcgc
     1201 cttcctcggc tcgggggtca ccgccctgtc cgccgaaccg ttccctttct cgcagttcag
     1261 cggcgaggag accgtcctct accgctaccg tgcggcggtg ggcggcgcgt gagcccccgc
     1321 agcaccggag ccaccgggcg cgggcaggct ccctgccacc acggcgagat cctccagggc
     1381 gtcttccgcg acggctcggg ccgcccgtgc ccggggctcg tcaccctgcc catggccggg
     1441 cccgggagca gcgccgtctt cacgatccgg cccggtacgg acccgcaggc gcccaccgtc
     1501 gcccccgccg ggcgcaccaa cgccgcccgg gccgccgcgc tcgcggtggc ggagtgcgcc
     1561 cggcgggccg ggctgccgcc ctgcgggggc gagttgcggc tcgcgggcga catcccggca
     1621 ggcctcggca tgggcagctc caccagcgac gtgatcgccg ccgtgcgggc ggtcgcggac
     1681 gcgtacggga cgcggctgcc ggccggggcg gtcgcccgga tcgcggcgcg cgcggcgggg
     1741 ccggcctgcg acccgctggt gccggacggg cggccggtgc tgttcgcgca gcgcgagggc
     1801 cgcgtcctgg aagtcctcgg cacggccctg ccgccgctgc tcgtcgtggg ctgcgacctt
     1861 ggcggcggcg cgcccgcgga caccctcgcc ctgcccgtgc gggaggccgg cgaggccgac
     1921 gtacgggcct gggagcggct gcgcgccctg ctgcgccggg cggtggcggc gcaggacgcg
     1981 cggctgctcg gtgccgtcgc caccgcccgc gcccggcgcg gcgagcgggt ggtcgggcac
     2041 ccggagttcg aggcgctggc cgcggtggcc cgacgggtcg gggcggtcgg cgtgcagatc
     2101 gcgcacagcg gggccgtggc cggcgtgctg ttcgacgccg gccgggcggc ggcgttgggg
     2161 ctgccttacc aggtgcgcgg ctgtttggac gccctggagg cccacggcat ccccgccgcc
     2221 cggatcttca ccacgcccgg cgtgcgcgcc cgcgcgtgcg cctccttctc cccttcccat
     2281 cctgccgcgg agctgctgtg gaccagcaca tcgcggagtc gacaggccac ccggacctga
     2341 tgcggctgga ggaccggctc gtctgcctcc gcttcgagac gatcacctcc gtcggcaggg
     2401 gcacttcggc cggtgctgtc gacgtgccgg gcggcgaccc ggacgtcctt ccggccacgg
     2461 caccggccgc cggcccggca cgtcgcacgc acgcctggcg ggtgagcgcc gcaccggggc
     2521 gcggctatga tgactgactg gtcggtcatc ttgggaggcg gagtggcacc acggcgggtt
     2581 gaccgggctg cgcgccggga ggagatcctc gcggcggcgg tgcgggtgtt cgcgcggcgt
     2641 gggtttgccg cgagccgtat cgaggatgtg gccgcggagg cgggcatcgg caagggcagt
     2701 gtctacctgt acttctcgga ccgagacgag ctgctggagg cggccttcgc tgcgctggcg
     2761 gcacgctcgg ccgcgctgat cgaggaagcg ctggcgggca cgggcgatcc ggcggagcgc
     2821 ctggagcatc tggtgcgttc cgtcgtggcc gtgctgcttg gcgaacggga tcttgcccgt
     2881 gtcctgctgg acgtgtggtc cgtggggcgt ggcggccgtc cgccggtcga catggcgggc
     2941 ttctaccgcg agtaccgggg cgcgatcgcc atgctgctgg ccgatgccgc cgacagcggt
     3001 gcggggccga cggtcgagcc tgtcgcgcac gccgcggtcc tcgtcggggc gatcgagggc
     3061 tgtgtgctgc agtggctctt cgactcctcc cttgatctgg ccggactcgt cgatccactg
     3121 ctgcagctgt tgataccggc ccgggcgaag ggaaggaacc cgtgatcaac ccgttgaagg
     3181 gcggtcctcc gcggacggcc ctgcgccgtg ccgtgctgcg ggcgccgatc cgcctctacc
     3241 ggatcgggct gggaggcctg ctcggccacc ggatgctcct gctcacccac accggacgcg
     3301 tcagcggccg gccgcgccag gtcgtggtgg aggtcctggc gccgggcggg cggcccggca
     3361 gctatctgat cgcgtccggc tacggcgagc ggtcgcagtg gctgcgcaac gtgctggccg
     3421 agccctgcgt ccggtaccag gtcggccggc ggaagttcga gggaacggcg gtgcccctgc
     3481 cgcccgagga atcaggccgg caactggccg agtacgcccg gcgccacccc cgcctggccg
     3541 cgaagctgat gcaggccctg ggccacaacc cgcaaagccg cgccgacttc gaggcactcg
     3601 gcgcagaccg acgcaacgga gttccgctgg tcgaggtgag cccgcaccac gggacggccg
     3661 ccggcggccc cgccctgccc ggatgacggc acaggccggc tgaggctgcg cccgccgcct
     3721 cacccgggtg ccggtcgccg gaccgggcat gccgatgccc cgtgcatgcc gcccgcgggt
     3781 ccgccgtccc cggatggcgg tggagccgac gcccgtggtg gagagacgcc tgggcgcgct
     3841 gccggcctgt gccggcttgc tgcgccgacc ggacgcggcc gggaccgtcg acgaccggcg
     3901 gcggcgcacg ccgtgcggac ttcgtgctcg acccggaccg gccggatggt gccccgggct
     3961 cggtccgagc ggtgctgcgt ggtcgacctg tgcggggcgg ccgccctgcc cacctggtcc
     4021 tgacgccggc tcgggacggt cccgttacgg aagcggcgcc ggcgcggagg cgacgagggc
     4081 ctgcaggacg tcgacggcgc tgccgtcgtg gtcgctgccg gaggtgcccg agccgttctg
     4141 gaggttggcg gagcggtcga cctcgactat cgagtcggcg tgggagttgt cgatgacggt
     4201 gatcaggctc tcgccggcca gggcgggggc ggccgcggcg gcggcgacgg cacaggccgc
     4261 cgacacggcg gtgagggccg cggccgccag ggaggccggt gtgcgctgtg cgggcagccg
     4321 cagccgggtt cggcgggtca cgcgccggcg ccttcgagga tgcgctggcg ggcgatgttc
     4381 cgggccagca gactggtgga ctcccggacg ccgatgccgc cggccgcggc gggctccggc
     4441 agccggccgt cggagagctt gagctcggtc agggcgtcgt gcatcgcgcg gtgcgcggcg
     4501 aagaggcagg gcgtgctgta gatcgcgatg tcgacaccga gttcggtgag ctcgcccagg
     4561 gacagccggg gtgacttccc tccggcgatc tggttgaaga gcagcggctt tccggcgacg
     4621 acctcgcgga tgcggcggat ccactcgacg ctgcgcaccc cgtcgacgag gaccacgtcc
     4681 gcgtcggtgg cggcgagcgc ctcggcgcgc cgcaggatgt cggcctcctc ggtcgcgtcc
     4741 gtccgggcga cgacgacgag gtctcggcgg gtggcgagga ccatgttcag cttgtcgagg
     4801 tattcggcga ggggcagcac ctgcttgccg tccgcgtggc cgcagcggcg ggggcgtcgc
     4861 tggtcctcga ggatgatgcc ggacgcgccg atgcgctcca ggctctcgac gacgtggcag
     4921 gcgacctcgg ggtcgacgta gccgtcgtcg atgtcgacga gcaggtcgtg gtcggggaag
     4981 gccccgcgca gccgctggac gaaggagagc atgtccggcc aggcgatgaa cccgatgtcg
     5041 ggcaggccgt agtacgaggc cgcgaaaccg aagccggaga cgaacatccc gtcgtagtgg
     5101 tcggccgcga tcgaggccga gtacatgtcg tagacgccga tgaggggggt ggtgccgggc
     5161 cgggcgacac gggcccggag cttgcttccg taagtcaacg cgtctcctcg aagggcgggt
     5221 gggaacggcc ggccgcagta ccgcgaaacg gtaatgcgga ggcaaagaaa gagtcatcac
     5281 gctttgtatc cgatcagacg cgcgaagcaa cacaagagcg tcggcgtgtc accctcgcgg
     5341 gtggcccggt tcaccgcaga aacgccacgc cgccggcgcc gcgagcggga cgcgaggcgg
     5401 accaagggag actcgagagc ccctctggca cctcctgcca caaggtccgg atccgatcgc
     5461 ccactgaccg atacatgcct gttgcaggca aatcttcgcg tgcacatgtt catggacccg
     5521 tccgtgtgac gggccggtac cggcccgccc gcttcgcccc cttcttccca ggagaaggaa
     5581 tgacgctgaa gctgctgctc gcgaacgccc ccaaccccac cgccaaccgc aacgcatcga
     5641 actacgcctg ccacccccac atcggcatcg tccaactcgc cacggcgacc cgggacgcgc
     5701 tgggcgaccg cgtggagata cgcgtcgtcg acggcggcat atccaacacg gccgccgtgc
     5761 agcgcgccgt ccgggacttc gctcccgacc tcgccggcat cagcgcactc acgccgacct
     5821 attcggaggc cctggagatc gcctcgaccg cgaaggcgtg cggggcgcag gtcgtgctcg
     5881 gcgacgacca cgcgatcttc ttccccgaga tgatcctgcg caacaggccg cagatcgact
     5941 acgtgatcgc caacgacggc ggtgagatac cgttcgtgca actggtccag gccctggcgg
     6001 acggcagcgg cgtgtcccgg gtctcgtcgc tcgcctaccg ggacggcggc cggatccggc
     6061 tcaacccggc tccgaagtac gccctctcgc tgcgcaacac gattcccgac ctgtcgttca
     6121 tcgaggacgt gctcggcacc tacgccgaca actaccgtgc ccagttcggc catctgcacg
     6181 ggcacgaggt gcgcccggtc acggtggaca acgcgcgcgc gggccctcgg gctgaccaag
     6241 cgcaacaacg tcgacaagct gcgccggctg ggcgtggtcc gcgcgaacgt cggcctggac
     6301 gccgccgacc cggaaatgct ggaggcgcag cggaagaaca ggacgaccgg tgagaccaac
     6361 ctcgaggcga gccgcatgct caacaaggcg ggcatctcgg tgcacgcctc gtacatcgcc
     6421 ggcgcgccgg gcgagcggcc ggagaccctg gaccgcacga tcgacggaat cccgcagatg
     6481 ctcggcgagg tggagctgtc atccgtcgag ttctcccggt tcattccgct gccgaacagt
     6541 ccggcgtggg acctcctcgt cgactacgag cgcccgaact tcttcaggaa cagcggcgac
     6601 atcgacgcct acctcgccgg tctgggaatc tccttcaccg gcgcggagcg tgcgcagatg
     6661 caggaccggt tcggggagcg ggacctgctc gacatcgacg agctgggcgc ttattgggcg
     6721 gacaacttca cacacatcag cgaggatcac gccttgcagc ggatcgcgga ggtcgacgag
     6781 atggtgagcg cccacaacgt gcgcaccggg aacaacgtcg gacagcgcgg gaaagggaaa
     6841 ggtgcccgaa tgctcggagt ggacaacctg ctgacgtaca ccgtcggcgc cctgctcatc
     6901 atcctgctgc ccgggccgag ttcgctgttc acgctgtccg tggccgcacg gctcggggtg
     6961 cgggccgggt accgggccgc ggcgggggtc ttcctcggcg agaccctcct catggcggcg
     7021 acggcggcgg ggctggcctc gctgctgcag accaacgacc tgctgttcgc catcgtgaag
     7081 tacgccggcg ccggctacct cacgtggatc gccgtcggca tgatccgggc ggcttggacc
     7141 atgtggcggc gccccggccg gtcggcgggg gcggacccgg agggggtgca ggcccgtgcg
     7201 gatgcggggg ccgggaccgc ggcggcgggg gcgcggctgt tccgccgctc gctggtgatc
     7261 acggtcctga acccgaaggc gatcctgttc ttcatctcct tcttcgtgca gttcgtcgac
     7321 cccggctacc cgcatccggc gctgtcgttc gggctgctgg ccctcgtcta ccagctgatc
     7381 agcatcgcct atgtcaccgc actgatcctg ggaggcacgt acctggcggc gcagttccgc
     7441 cggcggcgca ggctctccgc ggggctgacg acgggggcgg gggcgctgtt tctgggattc
     7501 gccgccaagc tggccacagc gggcaactga ccgcggggcg ggcgggcggc tgtccgcccg
     7561 ccccgccccg ctcaccccgc gtccagccgg aaggctgcct ccccgcgcag tctgccgttc
     7621 acctggagct ggacgaggtg ctcgccggag aagtagcggc gggtggtgag gggcttgaag
     7681 gagtgccgcc tggttccggc gagggtctcg cccggggcga gggtgcgggt ggccagtttg
     7741 aacaccttcg gggtgcggcg gccgttcgcc ttcacatggt ggacgacgta gtcgaggacg
     7801 agttcggcgg gcgtatcggc gtcgttggtg agggcgtact cgaagacgag gtgttcgccg
     7861 acggcgaccc gggcggtggc gatgaccggt ccgcggacgg tgaccggcgc gtcgggcgcg
     7921 tgcccgagga cactcatggc gtcggcgcgg ccggccttca cgagggtgcg caggccgtgc
     7981 cgggccaccc gcccggtggt ggccgcgggc gcggccagcc agcgtccggc cgtttcgacg
     8041 gcgagttcgg ggtggtcgcg gctgatgtcg ttgaggtggt tggcgaccga gcggcgcacg
     8101 tagtcggagt cgtcgcggta gagggcgttg aggaggggga gcgcgggccg cgggtcggcg
     8161 atggactcgg gcagctgcgg cgcccacggg agccggggcc gggtgccctc gctgacgagg
     8221 cggcggacgt gcgggtccgg gtcctccacc caggggccca tcaccgccag ggcgcggtcc
     8281 cggtcggcgc gcaggaaggg gcggaccgcg gactccgccg tcaggcgcgg ggtgaggtcg
     8341 cgcagcaggg cgagggccgg ctcgaacgcg gcgggacccg aggcgaggcc gcggaccgcg
     8401 accgcctccc ccacggggaa ggtcatccag ccggcgaatc cggggtcggc gagggcggcg
     8461 cgcacggagg cctcgaaggc gccccagtcg gcgggcaggt cgtcgagggc ggcgtcgcgg
     8521 acggcggcga cgcggccgct gaacgtcagg ccgtcgagcg cggacgcaca ggcgagcagg
     8581 gccggggcgg acctcggtcc ggctgccgcg gcgaggcggc gggcgaggtc ctggacggtg
     8641 cgcgcgctga gcagttcatc ggccgtgggc atggatcaag tgtgacggtt ccccggaccc
     8701 cggcggcgca cggcccctgg tagggcttgg tccccggacg tggttccggg cggggctgag
     8761 gaagcgcact cgggcgcgcg atggtgccga ctgcgccgga ggaccggcgg cgggagtcgg
     8821 gccggcacac cgggatcggg gccgggcgga gtcgcggtgg gggtggcgcg gagtcgggct
     8881 ggggccggcg tcgcggagcg gcggggcggg gcggcagcgt gcgggccggg cggtgcagtt
     8941 tggccggatc cggacggacc ggcggcggag gaggggggcg ccggccgccg ggtcccgccc
     9001 cggggtgccg cgcagccggg tcgcggaacc gtgcgttcct gacaggccgc cggatcgcgg
     9061 cgcgccgcac cacgcagcaa cgaccacccg cggccccggt ggaccggcct gcccgacaag
     9121 gccgcagcac aggccgctcg cggtccggtg gagttccctt ggactgccgc tgaggtgacg
     9181 aaccaggccg ggacaacagg ccaacgtgac acgcggactt gccgttggcc tggtccgccg
     9241 ccgagactcg gaacgcacca cgaacgaaca ctcattcgga cgccctccgg gggccgttcg
     9301 ccgcgttccg gggccgtccg gccccggccg atgcggcgat ccggcgacca cccgccccgg
     9361 gtcgctccgc tcgccggccg caggcgccgg acggctccgg cgcagttccc ggcggcccgg
     9421 caaccccttc caccagagag gaagtccgcc atgcccgaaa gcatcgccgg ccccgccccc
     9481 gagggcctcg acctcgactt ggacctcgac ctcagcgacc tggccatcac ggcgctgcgc
     9541 gacacgcccg ccctgccgga gagcggcgcg tcgtacggct cctgctcctg ccagggctcg
     9601 tcctcctgcg cccagccgca cacggacacg cccatcggct gacggcccac cgccgccgcc
     9661 cgatccaccc atccacgatc ccgaccacgc gagaggccgg cacatgaccg accccaccga
     9721 gggcgtcctc gccctggacg acctggacct cgacctcgac ctcggcgagc tcaccgtcac
     9781 ggcgctgcgg gactccgtcg cgctgcccga gacgggtgct tccggcggtg tgagctccag
     9841 ctcctgcggc tcgtcctcct gcgcccagcc gcggctcccc gaactgccct actgagcaac
     9901 gccgcccgtg cggccgaccc ctcggggccg gccgcacggg ccccggcgcc cagccgacga
     9961 ccctgcccca ggcccggatc cgcccccatg ggagcccacg atgccgcacc ccgccgagtc
    10021 ggccacgccg ccgcgcgccg ccgcgcgggc cgcccgcccg ctcccgcagc cgcccgcccg
    10081 gaccgccccg tacgcgctgg tccgcaccac ggtcacgccg cacccggccg agcccgaggc
    10141 ctccgcccgc gtacgggccc tcctcggcgg gctcgcccgg atcgccgcgc aggaggaggc
    10201 ggtgcgggcc ggcctgtgcg acgacctgtt cgcgtcccgg ccgggccact ccgaggactt
    10261 ccaccgccgg gtcgtgctcc cgctccgcag ggcgctgcac aacggccgcg cgccccgtcc
    10321 cgcgctgctg gcccggctcg gcgacctgcc cgtacgggtc ccccggctcg gcgcgtggct
    10381 cgccctgcgc ggggagcgcg ccgccctgct cgccgaggcc gacgacgccg tcccggcggc
    10441 cctggccgcc gagcgctccg ccctcgcgga ggtgtgccgc tcgcccggct tcacccgcgc
    10501 cgtcgccctc ggcagcacgg acctgctgcg cgccgtgtcg cgggccgccc gggacgaggg
    10561 cggacgccgg gcccgcaagg aggagccgtc ggtgctgcgc cacgccctgc gcgccaccgc
    10621 caagacgagt ccgctgtcct ggttcaccgc ggtgggctgg tccggcccgg ccccggccgc
    10681 cggcccgccc gcgttgcggg ccgtggtgcg ggagaaccgg acgctggtcg cggccctcgt
    10741 ctccgcgctg ctggacgagc cccggcgccg cggcgcgctc gcacaccggc tgaccagcag
    10801 tgccctgccg gccggcgacg gccgtgcccg ctacgtgcgg gacaccaccg tgttcgcggg
    10861 cggccggtac ctggtcaccc gcgaggagga ggtcgaggtc gccgcgcacc cggcgctggc
    10921 cgtcctcgac gggctcgcgg cgcagcccgc cccgccggac acgctcgccg cccggctcgc
    10981 cccggccctc ggccgcccgg aagccgaccc ggccgtccgc cggttcctgg accaactcgc
    11041 ggacaacggg ctgctcgtag cggttgatcc ggtcgatccg cagcatccgc agccgctgcg
    11101 cgccctcgcg gactggctgc gccggtggcc cgaagacgcc gccctcgccg accgcatcga
    11161 cctcctcgcc gccgacacgg cccggttcgc ccacaccccc gccggggaac ggcccgcgct
    11221 gctcgccgac ctcgccgacc gctggcgcgc cctgctcgcc gacaccggac ggcccgttcc
    11281 ggccggcgcg gccccgctga acgtgctctc cgaggacgtg ctcgccccgg gccggcccga
    11341 ggccccgcgg cctgcgccgg cctccgcacc ggccgccccc gggctcggcc cggtccccgg
    11401 ccggcccgac ccgtccggcg cccgccggcc cgccgccgcg gaccccgcag gcgatgcccc
    11461 cgcaccggca gccgcactgt ccgggagcga ccgggcggcc ctcgccgaac tcacggcgct
    11521 tgcggaactg ttcgacctcg gacacctgat gcggcgcgcc gcggtgcagc gtttcaccgc
    11581 ccgctacggg gtcggcggca cgtgccccgc gccctgggag ttcgccgcgg acaccgcggc
    11641 ctcctgggag gacgccgccc gcctcgccgc cctccccgcg gacgccccct ccctccctcc
    11701 gggtgcggcc gaactggccc ggctgcgcgc ccggttcgta cggctcgccg aagccgccgc
    11761 agccgcggcc ggcgggccgg aaggcccgcc cgacgaggtc gtcctgcccg ctgccgacgt
    11821 gcacgggctg gcagcccggc tgcccgaccg gaccgccgcc cggccgctcg gctatgcctg
    11881 gttcgtccag cacgccgccg gagcaccccc ggcggacgcc ggcggcggac tgctgtgcgt
    11941 caaccacgtc tacgccggat ggggccgctt caccagccgc ttcctcgacg gcctgccccc
    12001 cgcggcggcc cgtgcggtgg ccggcgagat ccgccggggc ctcggcgaag gggcccgggc
    12061 ggcgcagatc cggccggtgg gcggcttcaa cgccaacctc cacccgctgc tcacggacgc
    12121 cgagatcggg cccgaccggc tccgcggcac gatcgccgag tccgacgtgg acctggtgca
    12181 cgacccggcc tcggaccagc tgcgcctgcg cctgcgggcc accggcgagt tcctcgacgt
    12241 gctctacctg ggcttcctcg caccggtgat gctcccgcag cgcctcgcgc cgttcctgtg
    12301 cgaccacccc gaaggcgtcg tcgacttccg gcggctcctg cctcgcagca ccgcccccgc
    12361 ccccggcggc caggtggtcc gcacgccccg cctgcgccac cgccacgtgg tgctcgcccg
    12421 gcgccgctgg cacctgcccg aaggggtgct ggccgcgctg cgcgccgacc tcgcggacga
    12481 ccggggtgac gtgccggcgg ccgccgcggc ccgctggcgg gcgctgctgg gcctgcccga
    12541 gcagctgttc ctccatccgg tgccgcagcc tcccgcgggg cgcgccgccg aggacttcct
    12601 ggcggccctg cgcgcgccga agccgcagcc cctcgacctg ggcagcgccc tgcacctgcg
    12661 gtgcctggcg ggctggctgg cccgccatcc gcggggggtc gtgctggagg aggcgctgcc
    12721 cgccttcggg gggcgggacc ggccggcccg cgccgtcgag ctggtcgccg agacgcaccg
    12781 ccccgcccgc accggctgac cgccgcctac cccgccgcgc gggcccccgc ggggctcgcg
    12841 cagacaccac cgcccgtcat ccgccgagga ggcacccgat gaacgccccg gccgccggcc
    12901 cggatccggc cccgcccgcg ccgaccgcgc tcgacgtcgt cgtccaccac tacgagccgg
    12961 tcaaggcccc cctgctgcgc gagtccgtcc tgccgctcgc ccggcgggcg gccgccgagg
    13021 ggctcgccgt gcacgtcgag cgccactggc tgcgcggccc ccacgtacgg ctgcggctgc
    13081 gcggcgcgcc cgcgcaggtg gcggccgccg ccgagcggac ggccggggaa ctgcgcgccc
    13141 gtgcggccgc gcacccgtcg cgggccggcg tcgacgagcg ggagctgctg gagcaggccg
    13201 ccgcggcggg gcgtgcggag ctggtcccgc cgccgtacgg gccgctcgtc cccgacaaca
    13261 ccgtgcgcgt ggagcccgtc gacctggatc cgctgcgggc cctgatcggc cccgacggcg
    13321 tacggctgcg cgaggacctg atggcggcgg gcctgccggc gctggaggcc ggcaccgcat
    13381 tcctcggcga gcgcggggac acctcggcag cgcgcgtgga gctggtggtc accgccctgg
    13441 ccgcgcatgc ggcggcgcac cccgaaggcc tcgtcggcgg ccactactcg ttcctgtccc
    13501 acctggagga cttcctggtc tacgaggacc ccgacgggcg gctgcgggcg gccttcgaac
    13561 ggcgctggga ggccgcgggc gggcggatct ccgcgctggt gggcaggatc gcggccggcg
    13621 gcgccaccgg ccgcgaacgg gcctgggccg actggtccgc cggcgcctgg cagaccgcgg
    13681 aggagcggca cgcggcgggc gcggacctcg cgggcgtcgc cgccgagtac cgggcacggg
    13741 cggccgcgct cggcgaccgg gagaccgccg cccggtggaa ccgcgaagtc cgcacccggt
    13801 acagcgactt ccaccggcag ctgcaccgct ccgacccgga gggcgcgatg tggagccgcg
    13861 ccgactacct cgtctaccgg tcctgcacga acgccctgta ccggctgctg gccgtctgcg
    13921 acgtccgccc cgtggagcgg tacctggccg cgcacctggt cgtgcggagt gtcccggggc
    13981 tcaccgggca ccgctggcag gcccgcatcg acgaggtcat cgccgccgtg gagggcgccc
    14041 ggtgaccgcc ggcggggagc cgttcaccct gcggctgcgg ccgggtgtcg cggccaccgt
    14101 gctgcgggcc ggcctgcacc tgcgcgggcg ggacgggagc gtgacgctgg agggcagcaa
    14161 ggcgcttccc gccctctggg agctgctggc ggaccggctg ggcgcggagc cggccgcccc
    14221 cgccggcacg gcacgccggc cgggcgggct ggatccgtcg gacccgcggg tcgcgtcggc
    14281 gctggacggg ctcgcgggcc agctccgggc gcacgggctg ctcgcggagc tccccgaggg
    14341 cggggagggg ccggccgcct ggctggccgc gtccacggac cgcccgggcg cggcggccgc
    14401 ggcactggcc gccgccccgc ccgtcgtcac ggccgccgat ccgggcgccc cgctcgccgc
    14461 ggccctgctg cgggccctgc accgggcggg cgcgcggccg gaggctcgga ccgacagcag
    14521 gctgccgccc ggcctggtcg tggccgcggc cggcgccccg ccggtcgccg tggccgccga
    14581 ccggaccgcc gggggcggct tcgtcacggc cccgaccgcc cccgagcggg tgcgcgcgga
    14641 cgccggggcg gtcgcagccc ggttgggcgg caccgtcagc gcctctgcgg cggcagcagg
    14701 tgcggacgcg ctgacggccc tgctggcggg cgcggccgcc cagcggctgc tgtgcgccgc
    14761 cgccggactg cctgatcccg ccggggcgga cgaggaccag cggctgctgc cgggccgccc
    14821 cgccgtcctc gtcgccgagg ccgcgcctcc ccgggcgtcc taccacccgt gggcggccgg
    14881 gccggccgcg gcctcggagc ccgccctgcc cccggccgcc gacctggccg aagcgctgcg
    14941 ccgtgtcgga gcgctggccg accccctcct gggggtcctc gacgcccccc tgccgggccg
    15001 gctgccgcag ctgcccgcgg cgctcgccgc ctgccggacc cccgcagggc cactggtggc
    15061 gggagcgccc cgggcggacc tggcccgcct gaccgcggcg tgccgggcgg ccgaactccg
    15121 gctcggcggc gccgcagtgg taggggcggg gccggggcac gcgcggggcc gggccctgcg
    15181 ccgtgccgcc ctcgccgcct ccggacgggc ggacaccggt cccgcacttc cggaggaaga
    15241 gtggcgcgag cacccccagg cccgccactg gtgggcggtc ctcaccggca tcgcggggca
    15301 cgcgcaggcc cggttggcag tacgccagct gggcggggag caggcgtacg cggcggtcgt
    15361 acgcgttccc ggtgccccgg cgccgctcgg cagggcggtg gaggccaccc cggcggacgc
    15421 ggcggccgtg gccctgctcg gcgcggtcac ccgggccatg gccgccgacc acgggcccgc
    15481 cggggccgcg cacgccccgt tcagcggggc cgaggccccg ctcgcggcgg cgggcaccga
    15541 gccggcggcc tgggcggacg agggctggac cgacgtctgg ctgaccggga ccgcgcaccg
    15601 ggaggcagcc ctgaccgcgg ccctgacccg cctgaccggc ccggcccccg gcccgtggct
    15661 gccgccgggc ggcgaccccg tcgcagcccg gacggcgacg gtcctgcgca gttgcggctt
    15721 caccgtcctg gccgacccga aggaatcccc gtgaacggca caccgatccc cgcgacaccc
    15781 ggggccgcct gccccggcgc ggctccgcgc gccgcgcagc gggaccccgc ggcgctcccc
    15841 gccgcagcgc cctgcgcccc gctccccgac gccaccgcac tcgccggcac acagcacccc
    15901 ggctcggcgg gcccggcggc gcaggccgcc gaccgccccg gggagctgcc cgtcctggac
    15961 gtggaggcgg cgctcgccgc cgtctccggg acagccgtcg tgcatctggc ctcctggacg
    16021 ccggggtcgg ccgagcggct cagccgccac gcgctcgccc gtccggtgcg cctggtgccc
    16081 gtgcgcgagg acggggcgct gaccgtggtc ggcccggttc tggaacccgg ggcgcgggcc
    16141 tgtctggtgt gcaccgagta ccagcggctc gccagtgccg gaggacgcgt accgtggcgg
    16201 agccctcggc tccggctggg tggcaccggg acgccggcac tggcggaggg ggtcctgctg
    16261 ctcgccgccg ggctgctcga cgaggaggtc ccgcccgccg gggatcacgg cgtgccgtcg
    16321 gcgaccgtgt acgtcgtcca ggggagccgg gccacctggt ccacgcaccg ggtccggccg
    16381 gtcggcggct gcccggtgtg ccggccgctg cccgaggact cccccgccgc ggcggagctg
    16441 cctgccgtgc cgcggccgct gccggacccc gcggagctgc gcggccccaa cgaccgtacg
    16501 ggggcggagg cgttgcgggc ggagctgtac gacgagcggt tcggcccggt gcgccgcctc
    16561 ttccgtacgg aggactccgc gttcggcctg acgaccgcct gggtgaccga cggccggctg
    16621 ctcgacgacg gcgggtacgg ccgcgccgcg gacttccgct ccagcgagcg cgtggcgctg
    16681 ttcgagagtg tggagcggct ggccggcatg cgcccgatgg gccggcgcac cgcgctgcgg
    16741 gcctccttcg cggagctggg cccggacgcg gcggtggacc cggtccgact ggggctgccc
    16801 gacccggtgc accacgggca ccccgcctcc cggacggtgc cgtaccggcc ggacctggag
    16861 ctggactggg tgtacggctg gtcgctgacg gagggccgga cccgcgccgt cccggagcac
    16921 gtcgcctact gggacctgcc ggacccgccg gacggggcgc cgcccggggc acgggtggtg
    16981 tacgagtcgt cgaacggctg cgggctgggc aacagcccgc aggaggccgc cctgtacggg
    17041 ctgttcgagg tggccgagcg ggacgccttc ctgatggcct ggtacgcggg cacccccctg
    17101 cccggtgtcg ccctgcccgc aggcgacccg ctggtggcgg cgctggccgc gcgggcggag
    17161 ctgctcggct accggctgcg cctgctggac gccacgaacg acctcggtgt gcccgccgtg
    17221 gtggccgtgt gccgctacga gggccgccat ccggcggcgc cgcgcgcgtt cctcgcggcg
    17281 ggcgcgcacc acgatccgcg cgtcgcgatc cgctcggcgg tggcggaggc ggtcacgaac
    17341 gtccaggacg ccgctcagcg gccggccggt ccgggccggg cgcgcgaccc ggagcggctg
    17401 cggccgatgc tggaccggcc cgagctggtg gtgggcctcg acgaccatgt ggggctgaac
    17461 gcgctgccgg aggcgcagcc gcggctggag ttcctgttcg ccgacaccgg ggcggccccc
    17521 tggcaggagc ggtggccggg cgcgcccgca cccgtggccg acctgacggt gctgctgtcg
    17581 gagacggtcg cccggctggc cggtgggggg ctggaggtcg tcgtggtggc tcaggacgag
    17641 cccggtgtcc gggaccggct ggggctgcac tgcgcgaagg tggtcgtgcc gggcaccctc
    17701 ccgatgacgt tcgggcacgt caaccggcgc actctcggcc tgccccggct gctggaggtg
    17761 ccgtaccggc tgggccgcac cgcgcgcccg ctgcggcacg acgaactgcc cctgcacccg
    17821 caccccttcc cgtgaggttc cgatgacccc tcaggcgtac cctcccccgg cccgtcccgc
    17881 cgccgcttcc gcaccggcgg gcggctggca gagcctgcac ctgtcgctgc acaccggtgc
    17941 cgcggacacc gacgcgttcg tcaccggcgc tctggcgccg ctgatggacg cccggtacgg
    18001 gccggagtcc ggcggtgcct ggttcttcat ccggtacggc gaaggggggc cgcacctgcg
    18061 gatccggttc cgcgggccgg gggcggggcc cgtcgacgcg gcccggctcg cggcggagct
    18121 cggcggcctc gccgccgaca cggccccggt ggccgggccc tggccggtcc gccacggcga
    18181 ggtccacgcg gtgccgtacg agccggagac ggagcggtac gggggtccgg aggcgctccc
    18241 ggtcgccgag gaggtgttcg tgcacgcgac gcgcgccgcc gtggcagccc tgcgcgcgct
    18301 gcccgcgcgg gcggaccggc tggggccggc catggacttc gcgcacgcca ccgccgcggc
    18361 gctcggactg gacgagctgg cggccgcggg ctggcttcgc cggcatgccg cgtcctggcg
    18421 ctgggtcgcc gaggtgcggc cgctgcccgg ggccgccgtc cacactcgcg tgaactcggt
    18481 gttcgccacg cagcgggagg ttctggcgcg gcgggcgcgg gccgtgcgcg ccggggccgc
    18541 ggagggcggt gccgcgccgt ggctcgacga gtgggtacgg caggtccgcg cggcggacgc
    18601 cgtgctgcgg gcggtggtcc cggcgggcgg gccgggcact ccggagcggg cggatcggcg
    18661 gctgtgggtg tgggcctcgc aactccacat gctgttcaac cggttgggtg tggccccgga
    18721 cgaggagcgg gccgtgtgcc ggctcgcggg tcgggccctg ctggagccct cgggcggcgg
    18781 cgggccggcg gccgggccgg caggcggcgg gttcttcgag aggggtgcgc gcgccgcgga
    18841 ctaccagtac ctggagcgga gcaagttcca ggtcggccgc gggcaggaca cggcggtccg
    18901 ggacgtcccg cggccgcccg ccgtcccgga gggccgccgc gtcgaggggg aggtcccgct
    18961 gccggcggcg ccgctgccgc cggtttccct gggcggggcg ctgcacggcc ggcgctcggc
    19021 gcgcggcgcg ctgacggggc cgctcgacgc ggcggagctg ggtggcgtgc tgtggcatgc
    19081 gcacgccccg agtcacacgt cccggcaggt cacggccgac gggacagagc ggaaggcgcg
    19141 gcaccgcccg tatccgagcg cgggcgccct gtacagcgtg cgggtgcggc tgctcgcgtg
    19201 ggatgtggcc gggctgccct cgggcaccta ccactgcgcg ccggagcggc ggtcgctggt
    19261 gcgcctgggg ccggccccgg aggtggaggc ggtgaaggcg ctgtcctcgt acctggcgct
    19321 cccggagggc gacccggacg ccgtcgggat cgacgcggcg ccggccgtcc tggccgtcca
    19381 cctcgacctg gggctgctgc gcggccggta cgggctgcgg gcgctgcggc tcggcctgct
    19441 ggaggcgggg cacctggccc aggtgctcca gctgacggcg ggcgcgttcg ggctggcgac
    19501 gatcccgctc ggcggcctcc aggacgacct ggcgcacgaa ctgctgggct tggacgacct
    19561 cgacgagccc gtccagtacc tcctcccgct cggccgcccg gcgggatgac cgggcaggcc
    19621 ggacggcgga cagacggcgg tcaggctgcg gggcgccagt agccgaggcc gttcacccgc
    19681 tgcttgggca ggccgagttc cttgcgcagg tacccggtga gggtgcgggt ggtcgccgtg
    19741 tcgcaggcca gccagacgta cgcggtctgc gggtcgggcg ccaggccggg aagctctgcg
    19801 cggatgcgct cgacgagggc ggcgccgccg ccggagcggg ggacgcggcg gatgtcgtgc
    19861 cggtcggcgt cgagccggac gggcaggtcg gcgtcgtcct cgtgctgggt ctcgaaccag
    19921 atggtggccg gggtctgcgg gtgggcgtcc agcagggagt tgatggccgg cagggacgcc
    19981 gggtcgccta tcaccagcag ccggtccggg gccggtgccg gtgcggtgaa gccggtgccc
    20041 tgcacggtgg cgtcgatggt ggcgccgggc tccgcggtgc gcgcccagtc gctggcgacg
    20101 ccgtcgtgga gggcgaactc cagggagaag gtgccggcgg ccgggtcggg gtcgacgagg
    20161 gtgtaggcgc gctggtgcgg cttgccgttg tcggtgaacc acaggcggac ccacatggtg
    20221 gggtgcaggg agccgccggc ggcggcgagc agtccgccgt cggtgaagga gacgcgccgg
    20281 tagtgcgggg tgacctgttc cgccccggtg accgtgaacg tgaagtcctt gccgcgcagc
    20341 agcttgagga ccacgccctc ccagcccttg ccgaccgcca tgtccgcccc tttccctgac
    20401 gccgtatagt caggcgagcc taacctaata attttcgggg cgtggagcgg accccgcacg
    20461 gccggccggg ccggccgcgg ccccggcgac cggcgccccg caccggccgc gatccggccg
    20521 gacgccacga aggaacggaa gaaccgccat gagacccgag tccaccgccc tcgcatcgcc
    20581 gcgcgcggac gtctacaccg agaccgtccc cggcttcggc accgtccgct tcaccccggt
    20641 cgaccccgcg gcggactccg ccgtcctcca ctcgtgggtc gtcgaggagc gcgcccagtt
    20701 ctggggcatg atcggcgcga gccgggaact ggtgcaggag atctacgagg acgtggaccg
    20761 ccgcgacacc caccacgcct acatggtgcg gctcgacgac gaaccggtgg cgctgttcca
    20821 gacgtaccag ccctccgagg accgcgtcag cctgtgctac gaggtgcgtg agggcgacat
    20881 cggcgtccac ctgatgctgg caccggcgaa cgggcggccc cggcccggct tcagccgcac
    20941 gctgatcggc tcgctgaccc gcttcacctt ccgcgacccg gccgtcctgc gcgccgtcgg
    21001 cgagcccgac gcccgcaacg cgaaggccgt cgcgatgctg ggccgcctcg ggttcgtccc
    21061 gcagggggag atcactctgc cggaaatcga cctgccggag atatacctcc cggagaagcg
    21121 agccgtgctc gccttcctcg accgccctgc cgtgctgccg cccgccgacg ggagcacccc
    21181 gaccccctag gaacccgtat gcccgcagcg caccggaacg ccacggggct ccggcccccg
    21241 gactcccgca ccgccggcgg cctcggccgc atcgccctgc gcggcgtcga cccggcggcc
    21301 gacgccgcgc tgatccaccg ctgggtgagc caggagcggg cccggttctg ggggatgggc
    21361 ggcgcggacc gcgaacgggt ccgcgaggtg tacgaggacc tcgaccgccg ggacacccac
    21421 catgcgttcc tggccctcct ggacggcgta ccggccgcgc tgttccagtc gtacgactgc
    21481 gcggccgacc gggtgtcgga gtgctacccg gtccggccgg gcgacgtggg cgtgcacctg
    21541 ctcatcgggc cgccgtccgg cccgccccgg ccgggccaca cggcggccct gctgggggcg
    21601 ttcctgtcgt acctgtgggg gctgccgggg acccgccggc tcgtcgcgga cccggacccg
    21661 gccaaccaca gggcggtggc gaggctggag cgcaccggct tcgtacgcgg cccggaggtc
    21721 ggactccccg ggatcgacct gccggaggtc cgcatccccg ccaagcgcgc ccgcctcctc
    21781 ttcctggacg ccccgccgcg gccctgacct cagggggcga tgggcagctg ccgcttgtgc
    21841 tcggtggccc ggtagcggcg ggcgatgatg tcgaaggccc gctcgccgac cggcttgccc
    21901 tccaggaagt cgtcgatgtc gtcgtacgtg acgcccagcg cgtcctcgtc cgccttgccc
    21961 gggtcgaggg tctccaggtc tgcggtcggc accttccaca ccagctcggc cggggcgccc
    22021 agcgcgtcgg cgacggcgcg cacgcggcgc ttggtcagtc cggtgagcgg cacgaggtcg
    22081 gcggcgccgt cgccgaactt ggtgaagaac ccggagaccg cctcggccgc gtggtcggtg
    22141 ccgacgacga ggccgtcgta cgcgccggcg accgcgtact gggcgatcat gcgctggcgg
    22201 gccttgatgt tgccctggac gaagtcctgg tggtgggcgt cgcggaagac gacgcccgcg
    22261 gcgacggcgg cggcgagtgc cgcgtcgctg gcgggcttca cgtcgaccgt caggacgtgg
    22321 tcggggcgga tgaacgacag cgccagctgg gcgtccttct cgtcggcctg gacgccgtac
    22381 ggcaggcgca tcgcgtagaa ggccgcctcg tgcccggcgg cgcgggcgcg ctccacggcg
    22441 agctggcaca gccggcccgc ggtggtggag tccacgcccc cgctgatgcc gaggacgagg
    22501 gagcgcaggc cgctcgcggt gagcttcccg gcgaggaagg ccacacggcg ctcgatctcg
    22561 cgctccgcgt cgaaggcgtc ggtgacctgg aggtcccggg cgatctcctg ctgcagggcg
    22621 gtggacgccg gctcgctcac ggctgctcct cggggtcgtg cgcgtgggta cgcgggggcg
    22681 gttcgctgtt ccgcaccgac cctagcccaa tcggccgtgc ggccttcctc cggccgcccg
    22741 gcggccggtc cggccgggct cctgccgggg tcctgccggg gtgcggggtg gggccagggg
    22801 ctacggggac agttcgaggt aggccggccg cccctgtctg cgcgcggcca gcgccgcctg
    22861 ccacacgggc agcacgtacg gcgggaccat gtccgcggtg acgtcctcgg gccggcagaa
    22921 gcggatctcg ccgatctccg actcctggag cgtgatccgc tgctgctgct ccggggtcag
    22981 ctgcgggccc tcgaagacgt ggaagacgtg cgcgcccccc ggacgggcca gccacgcggt
    23041 caccagcagg ccgccgacct ccaggtccag gccgatctcc tcgcgcagct cgcggcgcag
    23101 cgccgccgtg gggagttcgc cctcgtcgag gtggccgccc ggcaggttcc accgctcgtt
    23161 gtggaccggg ttgacgacga gcacccggcc gtgtccgtcc gtgacgacgg cggcagccga
    23221 cgcggtggcc gtggtgcggc gcgcgggcgc ggtcatgggt gctcctgtca cggcggggcg
    23281 ggcccgccgc ttccggccgg cggggtcggc gctcaccgta acaacgcggc cgcagacggg
    23341 ctccgtgggc ccgggccggg acaggggcgg ggcccgcggc cggcgcacga ggggggcgca
    23401 cagggcggag cccatcgaca gggtgtcgcc gcccggtcac actggggcac ggaggtggca
    23461 catgacggaa cgcgaacgcg cgcgcgaacg gaccgacggc atgcggcccg ccgtccggga
    23521 gacatacggc cccgcggacc tcagcgcggt tcccgtcttc gccggcggct tcatcaactt
    23581 cggctactgg cagccgggcg acctgggccg ccccctgacg gtcggcgacc gtatccgcag
    23641 ccaggaggac ctgtaccggc acgtgctgga caccgtcggc cccgtggagg gcggcgaggt
    23701 gctggaggtg ggatgcggcc tcgcggtggg ctgcgcgctg gccctggagg agtacgcccc
    23761 ggcgcggatc accggcatgg acatccaccc ccagcagctg gaacgggccc gccgggccaa
    23821 cacccgtgcc ctggcggcgg ccgggccggg ccggttccgg ctggtgcgcg gagcggccga
    23881 gtggatgccg ttcggggagg ccgagttcga ccgcgtctac agcgtggagg ccgcccagca
    23941 cttcgacgac ctggaggcgt tcgcggcgga ggccgccagg gtgctgcggc cgggcgggcg
    24001 gctcgccgtc gcgagcttct tcgccgccga cccggccgcc ccggagccgc tggcggcact
    24061 gctgacgacc ttcgccgacg ggctggacat cgcccggcag cccgcggacc tgacggacgc
    24121 cctgacccgg gcagggctgg agggcgcgcg ggcggagtcc atcggccccg ccgtgtggcc
    24181 cggctgggac cactggctgt ccgcccagtg ggagccgggc acctggccgc ggaacttcct
    24241 gcacgcctgg gagcgggggc tgctcgacta ctacgtcgtc accgccgagc gcccccgcgc
    24301 ctgaccgcta cggcctgggc agttcgcgcg tcagcttcga ctgccacggg caccaggtgg
    24361 aacgcggcag gagcgccccg cccacctcgt ccaggtgctc gtccacgtag gcgatgctcg
    24421 cgtcgcagac ctccatcgcc atgccgaaga actgcaccga gttcggatcg agatggtagg
    24481 tccacggctt gttgtacgag gcgggcgtct tgacgacggt gcccatgaca ccgcggtgct
    24541 cggtgtcggc gccgctgagg atgttccggg cctggcggat cttggccggg tcggtgagct
    24601 tgatgacgaa cgtgtccgtg ccgtccgtga actcgaagta ggtggcgcgc gccgccgcgg
    24661 acaccgtgtc gccttcggcg ggctgggcgg cctgggcggg ctggcccagc gccagcgcca
    24721 gcatcgagac tgccgcgaca ctgccggcgc gggtgaggat tcgtcgcatg accggtacct
    24781 ccgtacctga tgggtcgtat ggggcctttc ggcctttcgc aacgcaccgt atgcaactca
    24841 ccagacccaa tggccacttg ggacatgaaa ctgcctcaaa ggacaccaag tgcacccacc
    24901 accctgcccg gagggccacg ctccgcagtt ccggcggccc ggctgcccct ccgcccgcat
    24961 ccccgctccc gacctgccgt cccggcccgc ggagccgccc gcgagggcgc gggcgcggcc
    25021 tgcggtgggg cgtctggacg ccagtcggcg catgcggttc cgggcgacac ccgctccggc
    25081 ccctggggcg ggttgtcggg tggtagtgca ggggaccggc ggggtaggtc tgcagtggcc
    25141 tgcgggtggt ccgcggccgc gggccgcggg cggcccggca cgggggaagg gaagcatcgt
    25201 gggaagcgga gtgggcgcag gtggagatcc ggccggtgcg gcgcatgccg ggcagccggt
    25261 gacggccgcc gagttgttcg acgggctggg gatcgcctac gaggaggcgt tcggcaggct
    25321 gcccgcgcag tcggacgccg tcgactggct ggccgcccga ctggcgcccg gcgcccgcgt
    25381 cctcgacgtc ggcagcggta cgggccgccc ggtcgccgag cggctcgccg acgccgggtt
    25441 cgaggtgacc gggatcgacg tgtcacgcgt catggtcgaa ctggcccgag cccaggtccc
    25501 gaaggcccgg ttcgagcagt gcgacgtacg ggacttcgcc ccggagggcg gcttcgacgc
    25561 cgtctgctcc ttcttcccgc tgctcatgat gagccgggcg gaggcatcgg ccgcattgcg
    25621 gcggatggcc ggctggctgg tgccgggcgg ctacctggtg tcggccaccg tgccggccga
    25681 cgtggaggac gccgaagtgg agtggatggg gcggcgcgtg cgggtgtcga gctgctcgac
    25741 cgacgcctac ctgcgcctcc tccgcgagga ctgcggcctg gagctcctgc accactccgt
    25801 ctccctcttc ctcccggacg gcggactggc ggcaccggag gagcacctct tctgctacgc
    25861 ccgccgcccg gtcgacgggg agtgagggcg agccggcgcc gcgggggcgg acagggagag
    25921 gaacggcggg gcggggcggc gagggcggag ctgacgggtc gcatgcgggt gcacctttcg
    25981 acggggagca gagacagccc ccgaccgcag ggacgcggcg gtccgctgtc gcggtacccg
    26041 gccgcgtcgc ggcgcgcccc atccgaatgg cgccgtccga atggcgcagc tcccgctacg
    26101 cggggaggtt cagctgccag gagacgccga agcggtcgct cacccagccg aacttggggc
    26161 tgaagccgta cgagcccagc ggcatcagtg ccgcgccgcc ctccaggagg gcctcgtaca
    26221 ggcggtccag ttcggcctcg ctgtcgcact ggacgaagag ggagatcgcc ggggtgaacc
    26281 cgaagtcgtg cttggcgggg ctgtcgatgc acatgagctg ctggccggcg agggagaaca
    26341 cggcgtgctg cacagtgccc tcggggccgg gctcgccggg gccgtagcgg gtgatgtcga
    26401 gcacctcggc gtcgtcgaag agcgaggtgt agaaggccat cgcctcctcc gcttggccct
    26461 cgaacatcag gaacgtggtg atcttctggg atgtcgcggc catcctgcct gctccaagga
    26521 ggtggggtgc ggctgtcggt gcgacagtag ggcacacggc agccgaaacc ccgtcaactc
    26581 cccctgccgt gaggcgaacc cgtacccctc ccctatcatc tgttcgattc tcgactcccg
    26641 tgggcgttca cgtccgcacg ggagcaaaca cgatgagagg caacggggac ttgggattca
    26701 aggccggata tcggatatca gtggtcggcg cgtgcgccgt ggcggccatt gcaggaggaa
    26761 tcatgtcctc cagtgccttc ggcacggagg acggcggtga cggcccgcag gccgcgcagt
    26821 cggcgccgct gccggcgccg gacgtgcacg cggcggacac cgccccgtcg cgcaccgacc
    26881 acaccgcgtt ccgcgacggc gtcatgcacc tcggcggcga cacggcggcg cccgccggag
    26941 caggcggctc cgcgaaggcc gccgcgggtg cggccgcccg ggcggcggcc gccgccgctc
    27001 ccccgcaggg cgaggggtgg aagctgagcg gagccacgaa gtggctggcg accggctaca
    27061 cgatcaagtt ctacgaccag aagtccgcgg actggctggg cccctacgcc aaggccacgg
    27121 cggcggacct ccagcggatc acgaacctgc cggtcaaggt cgacaccaag ccggtgggct
    27181 gggagtactc ccgcccgaag ggcgaggtga tcctgggcgt gctgcaccgg ccctgcctgc
    27241 cgccggacgg cgacatcatg ggcaacaccg gttggaaggt cgtccgcgac ggctccggca
    27301 tggccaacct gagctgcggc ttcaccagct cctcggtgcc ggagacggtg accagcgggc
    27361 acgcgtacat cgacagcgag ttcttcaccc cgcagggcaa gccgaccgcc gccatgggcg
    27421 agacgtacat gcgcaaccac atcagccacg agatcggcca caccctgggc ctgacgcacg
    27481 cgaatcgcag catgaagcgg agcgactgcg tcaagggcac cgactccggc cagttccccg
    27541 tcatgtgctc gcctgcgtac gcgtaccagg acaagcgggc cggcacgtac gtgcagcagt
    27601 tcgacgtcca gggcttccgc aggctggccg cgggcgcggg cgccgtgctg cccccgcagg
    27661 ggaaggtctc cggcatcgcc gggaagtgcc tcgacgccag gggcggcaag gcggccaacg
    27721 gtacgcagat ccagctctac acctgcaacg gatcggtcgc gcagtcctgg atcctcggca
    27781 aggacggcac cttccgggcg ctcggcaagt gcctcgacaa tgcgcgcaac ggcagcgcca
    27841 acggcaacaa gatccagctg tgggactgca acggctccgc cgcgcagcgc tggtcggtga
    27901 acgccaaggg ccagatcgtg cacgtcgcgt cgggcaaggt gctcgacgtg aagggcggcg
    27961 cgaccgcgaa cagcaccgtc gtccagctgt acacgccgaa caccggcaag ggccagctct
    28021 ggaaggcgcc gaagtagtcc ggtcccccgc cgctgcggct cagcccggga gcagggcgtc
    28081 gacgacgtcg acgaccaggt cgcccagcga cctgccgccc gtgccgaacg cggcggcgag
    28141 ggcgtagccg acggcggcgt cctgcggctg ggggccggcg ccgggcagcc agtccgcggc
    28201 gacggacccg tcgcctcggg aggtgaactc cccgaggcgg cggccgtccc gcaggaacct
    28261 gctggccgtc gccgagcagg gcaccaggcg gtagcggctg ccgccggcgc gggcgtcgac
    28321 gcggtaggag cggcggggga tccaggcccg ggccgggcgg atgccggccg ggccgccgtc
    28381 cacggtgagg gtgaggcgtc cgccgtcgcg ggtgccgatc ggcgcgtacc ggttcggctt
    28441 ggcgccgcca ccgcggacca gccgcacctc gggcagcgcc ccgcccgcca cggccaccgt
    28501 cccccggccg gcgtcgaggc ggacgtcgac gggcccgaag cactcgtccg cgacgggccc
    28561 ggacgggccg gccgtactgt cgccgccgaa cggcggctcc gcgtcggaga acggcaggga
    28621 cggatcgtgc atggcggtct tcctcggagc cgaagggacg gacgggccgc cggccactgc
    28681 acgcccggca cccccgacca tgatcgccca cccggcggac gcatcgcacg cgagacggcc
    28741 cggcagccgg gccatgggcg acgatggtgc ccatgtccga acgattcacg acccgagtcc
    28801 tcgacctcac cacaggccgc accgagaccg tgaccgacct gacccgccac tgcgagcgct
    28861 tcctctccga cgccgcagcc ggccgcgacg gcctcctgaa cgtcttcgtc ccgcacgcca
    28921 ccgccggcat cgcggtgatc gagacgggcg ccggcagcga cgacgacctc ctcgacgccc
    28981 tccgcgccct cctccccgcc gacgaccgct ggcgtcaccg ccacggctcg cccggccacg
    29041 gccgcgacca cgtcctcccg gccttcgtcc cgccccacgc aaccctgccg gtcgtggcgg
    29101 gccgcctgga actgggcacc tggcagtcgg tctgcctggt ggacaccaac aaggacaacc
    29161 cgcaacgcca ggtgcgcctt tcgttcctcg gctgagccga ggatcagggg gcgatgtccg
    29221 acggctgcac tcccgggtgt ggaacctgac ggtgtgccgg atgcgcttta ccccaccatg
    29281 ttcggggcgg caagccgtct cacccgaagg ggtggtgaac gcgttgaccc gtctggtcgg
    29341 tggggtgggg ttcccctacg gtcgggcccc ggtcgtcgct cgcggtgcgg ggcggcggcg
    29401 tgggagcagg ccgggactgg gagaggacgg cacagggtgg tcatgcacga ggactggacc
    29461 gacggcgcgg tgtgcaggac cgccgacccc gacgagctct tcgtgcaggg cgcggcccag
    29521 aaccaggcca agtcggtgtg cgggagctgc ggggtccgta cggagtgcct cgcctacgcc
    29581 ctcgaccagc ggatcgacca cggcatctg
//
