LOCUS       NZ_CP030862            51792 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces globosus strain LZH-48 chromosome, complete genome.
ACCESSION   NZ_CP030862
VERSION     NZ_CP030862.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces globosus
  ORGANISM  Streptomyces globosus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6863360)
  AUTHORS   Ran,K., Li,Z., Wei,S. and Dong,R.
  TITLE     Draft genome Sequence of streptomyces globosus LZH-48
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6863360)
  AUTHORS   Ran,K., Li,Z., Wei,S. and Dong,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2018) Institute of Biophysics, Dezhou University,
            566 DaXuexi RD, Dezhou, Shandong 253023, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Portal v. version 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003325375.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:22:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,671
            CDSs (total)                      :: 6,576
            Genes (coding)                    :: 6,458
            CDSs (with protein)               :: 6,458
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 41 of 118
            Pseudo Genes (incomplete)         :: 101 of 118
            Pseudo Genes (internal stop)      :: 11 of 118
            Pseudo Genes (multiple problems)  :: 32 of 118
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:39:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3722247
            Orig. end                         :: 3774039
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030862.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..51792
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="hglE-KS"
                     /product="T1PKS"
                     /region_number="22"
                     /rules="(hglE or hglD)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..51792
                     /SMILES="CC(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(hglE or hglD)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="neighbouring"
                     /product="hglE-KS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..47131
                     /SMILES="CC(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(hglE or hglD)"
                     /kind="single"
                     /product="hglE-KS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..47131
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:27131](+)"
                     /cutoff="20000"
                     /detection_rule="(hglE or hglD)"
                     /neighbourhood="20000"
                     /product="hglE-KS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..27131
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(hglE or hglD)"
                     /neighbourhood="20000"
                     /product="hglE-KS"
                     /protocluster_number="1"
     gene            200..667
                     /locus_tag="C0216_RS16245"
                     /old_locus_tag="C0216_16220"
     CDS             200..667
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474094.1"
                     /locus_tag="C0216_RS16245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16220"
                     /product="VOC family protein"
                     /protein_id="WP_114055977.1"
                     /transl_table=11
                     /translation="MAVKPVPEGYPRITPYLCCDGAAEAIDFYVSVLGATERTRMPAPG
                     GRIGHAELELGNSVVMLADEHPDMGFRSPKSVGGTPVTLHVYVEDVDAVFAAAVARGAR
                     ELRPVRDEFYGDRTGQIEDPYGHRWSLASHVEDVSEEEMERRAREAVQGGG"
     gene            872..1744
                     /locus_tag="C0216_RS16250"
                     /old_locus_tag="C0216_16225"
     CDS             872..1744
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025215.4"
                     /locus_tag="C0216_RS16250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16225"
                     /product="DUF4190 domain-containing protein"
                     /protein_id="WP_114055978.1"
                     /transl_table=11
                     /translation="MSIPPQPPPGPYQQPYPPQGPYGLPGQPGMPGVPGQGAPFGGPQG
                     WYPPQPQKTNVAAIVALVMSVVCAIPFVPLILGFVALSQIRKNGEKGKGLAIAAIVIHG
                     ATIAFYAIVLAIGLLGGAADDAAARQDAGGRVTVPEQSASPGANAGASPGASPRERRRD
                     VEDIRKGDCFNTEDDLAKTEEGGTEARQSVRTVACDQPHEGEVYAVLTLEGGAFPGADK
                     VVASADEKCGGKALTDYVGSDAAKLPKSLEVFYYYPQASSWVLGDRTVTCFLGSPAGTT
                     TGSVRANAS"
     gene            complement(1834..3021)
                     /locus_tag="C0216_RS16255"
                     /old_locus_tag="C0216_16230"
     CDS             complement(1834..3021)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982350.1"
                     /locus_tag="C0216_RS16255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16230"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_114055979.1"
                     /transl_table=11
                     /translation="MTSTPVLPSRTEVAIVGAGPTGLALAVTLAEAGVDFVLLDRQAEG
                     ANTSRAAVVHARTLEVFDELDPSGALSAGLVARGIPVSRFRIRDGARPLAAVDFDGLPT
                     AHPYALMVPQYETEAVLLSRLRALGGDVHRPREVTSVTQDADGVTLTTAAGETLHAAYA
                     VGADGMHSTVRAAAGIGFTGSAYDESFVLADVVMDWAPGPSEVSLAFGAAGLTVIAPLP
                     GNGNGGVGGGGGAGRRYRIVATVAEAPPSPDLAFVRALLAQRLRGEARVHDLVWSSRFR
                     IHHRVADRYRAGRLLLAGDAAHVHSPAGGQGMNTGIQDGYALGRALADGDLDAYEARRR
                     PVAQRVVALTDRMTRVATARGLTRRALRNTLLPVLARIPAFRNRLARELAELDYR"
     gene            3128..3688
                     /locus_tag="C0216_RS16260"
                     /old_locus_tag="C0216_16235"
     CDS             3128..3688
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145468.1"
                     /locus_tag="C0216_RS16260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16235"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_114055980.1"
                     /transl_table=11
                     /translation="MTTPRRSDQTKTAILRAARERFAAHGYERTTIRAVAADAEIDPSM
                     VMRYFGSKEQLFDAALAVDLRLPDLGAVPAEQLPATLVRHFVDRWEGDPADDALLVLLR
                     SAVTNEQAAARMREVFATQVAPALAAALGPDRAARTAGLVAAQLLGLALTRYLLALPPV
                     VALPPDDLVKRLAPALAATLAGY"
     gene            complement(3685..4095)
                     /locus_tag="C0216_RS16265"
                     /old_locus_tag="C0216_16240"
     CDS             complement(3685..4095)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS16265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C0216_16240"
                     /product="hypothetical protein"
                     /protein_id="WP_114055981.1"
                     /transl_table=11
                     /translation="MTATPDPDRRTAVDAEFRIDHLRAVDETRATAAVRCTHGPVRLGA
                     RFHRLRDAAAPIDLVLTRILFYGRPVDALDPACTALVTLRGAGTTLLAPGAGAGPPTIQ
                     GANPPPCAGPSRAPRARTERRSLLHGATQYSP"
     misc_feature    complement(4237..4250)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 15.96"
                     /tool="antismash"
     gene            4240..5139
                     /locus_tag="C0216_RS16270"
                     /old_locus_tag="C0216_16245"
     CDS             4240..5139
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031852.1"
                     /locus_tag="C0216_RS16270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16245"
                     /product="NAD-dependent protein deacetylase"
                     /protein_id="WP_114055982.1"
                     /transl_table=11
                     /translation="MRMRPTLSWTPSGDLPPGTTELGPVVDVLAAGRVLVLSGAGLSTE
                     SGIPDYRGEGGSLSRHTPMTYQDFVSGSGARRRYWARSHLGWRTFGRARPNAGHRAVAA
                     FGRHGMLAGVITQNVDGLHQAAGSDGVVELHGGLDRVVCLSCRASTPRRELALRLEEAN
                     PGFEPVAAAMNPDGDADLTDGQVADFRVVPCARCGGVLKPDVVFFGEAVPPSRVEQCRA
                     LVDGADAVLVLGSSLTVMSGLRFVRQAAGAGKPVLIVNRDATRGDPHAVTRVALPLGAA
                     LTAVAGRLGVAVDGEEAG"
     gene            complement(5158..5322)
                     /locus_tag="C0216_RS33525"
     CDS             complement(5158..5322)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS33525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162793237.1"
                     /transl_table=11
                     /translation="MTDPQGKARKDELNRQRKQEQERERARAGHEPDPGQDAQTDPQEG
                     ARPRKDQGG"
     gene            complement(5575..6321)
                     /locus_tag="C0216_RS16275"
                     /old_locus_tag="C0216_16250"
     CDS             complement(5575..6321)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (32-139). E-value: 1.7e-11. Score:
                     34.7. Matches aSDomain: nrpspksdomains_C0216_RS16275_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152071.1"
                     /locus_tag="C0216_RS16275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16250"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_114055983.1"
                     /transl_table=11
                     /translation="MSVQQQYDGIGEAFEGFKSLPLIRHGEVPSFLGMVGDVKGRSVLD
                     VACGTGFYSREFKRRGAADVFGVDISAEMIAAARRIEEQEPLGVRYEVGDAAGLGQLDR
                     QFDIALAVQCLNYASDTAEMERMCRNIHRNLVPGGAFFVFAQKPDYRFDCRSLDTYGFR
                     CEPTGEEREAGPLVRVTALLDPEPISILGTVPRREVYEECLRRAGFRDLEWVPLHVSEE
                     GIAEYGADFWADLLAHPPLEMLRCRS"
     aSDomain        complement(5905..6225)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16275_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.70E-11"
                     /label="C0216_RS16275_oMT.1"
                     /locus_tag="C0216_RS16275"
                     /protein_end="139"
                     /protein_start="32"
                     /score="34.7"
                     /tool="antismash"
                     /translation="GMVGDVKGRSVLDVACGTGFYSREFKRRGAADVFGVDISAEMIAA
                     ARRIEEQEPLGVRYEVGDAAGLGQLDRQFDIALAVQCLNYASDTAEMERMCRNIHRNLV
                     PGG"
     misc_feature    6537..6553
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 18.65"
                     /tool="antismash"
     gene            complement(6558..7166)
                     /locus_tag="C0216_RS16280"
                     /old_locus_tag="C0216_16255"
     CDS             complement(6558..7166)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031251.1"
                     /locus_tag="C0216_RS16280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16255"
                     /product="TIGR03086 family metal-binding protein"
                     /protein_id="WP_114055984.1"
                     /transl_table=11
                     /translation="MTDAAFIDLRPQARIVARLAADVPDDRLADPTPCPGYRVGGLLAH
                     LAGLATAFRDAARKDLGPTTATAPDAGSVPGLPAEWREQLPRLLAEMAVAWRDPAAWTG
                     MTRAGGVELPGGVAGAVATDELVIHGWDLARAAGLPYDPDPAALHASYAFLRASAEEDD
                     AGRGGIFGPVVPVPDDAPLLDRAVGLSGRNPLWTPPPTP"
     cand_cluster    7200..51792
                     /SMILES="CC(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    7200..51792
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[27199:31792](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      27200..31792
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     gene            7404..7838
                     /locus_tag="C0216_RS16285"
                     /old_locus_tag="C0216_16260"
     CDS             7404..7838
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010471007.1"
                     /locus_tag="C0216_RS16285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16260"
                     /product="hypothetical protein"
                     /protein_id="WP_114055985.1"
                     /transl_table=11
                     /translation="MTPLLLADIERAVRDSWSADTCTPDYRSLWTGDNPARDQCGVTAL
                     VLNDLLGGELVRGEVHVDGRRVDYHWWNRLGAGVEIDLTREQFGPEETVVGGTVIPRPP
                     RAQPHRLREEYELLRTRVLERLAQPPGERTGPASATPPAG"
     gene            complement(7972..8670)
                     /locus_tag="C0216_RS16290"
                     /old_locus_tag="C0216_16265"
     CDS             complement(7972..8670)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (4-126). E-value: 1.6e-09.
                     Score: 29.7. Matches aSDomain:
                     nrpspksdomains_C0216_RS16290_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971194.1"
                     /locus_tag="C0216_RS16290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16265"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_114055986.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6e-13, bitscore:
                     48.4, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.8e-05, bitscore: 23.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANFVLVAGAWLGGWAWDEVVPALRRAGHGVHPLTLSGLAEKRHV
                     PVGRQTHVRDIVDEVERLDLHDVVLVGHSYSGIPVGQAGGRISDRLTRVVFLDSNVPAE
                     GESFVSTWWEGPAKLEDAIAANGGLWAPVTAADCAGQGLGDRQIARFTAGATPHPGASL
                     ADPAVLVRPLEELPATYVKCLLDGAEPTDDVARLLTGPRWRRIDMATGHWPMFSQPQEL
                     ARLLLDAAGA"
     aSDomain        complement(8293..8658)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16290_Abhydrolase_1.1"
                     /evalue="1.60E-09"
                     /label="C0216_RS16290_Abhydrolase_1.1"
                     /locus_tag="C0216_RS16290"
                     /protein_end="126"
                     /protein_start="4"
                     /score="29.7"
                     /tool="antismash"
                     /translation="VLVAGAWLGGWAWDEVVPALRRAGHGVHPLTLSGLAEKRHVPVGR
                     QTHVRDIVDEVERLDLHDVVLVGHSYSGIPVGQAGGRISDRLTRVVFLDSNVPAEGESF
                     VSTWWEGPAKLEDAIAAN"
     gene            8811..8954
                     /locus_tag="C0216_RS34445"
     CDS             8811..8954
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS34445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_246042573.1"
                     /transl_table=11
                     /translation="MHQREWKPADHRLGIERAGIAVLAVAAALAAAAAIAVLSVVTVHA
                     LA"
     gene            9085..9600
                     /locus_tag="C0216_RS34450"
     CDS             9085..9600
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523335.1"
                     /locus_tag="C0216_RS34450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_246042574.1"
                     /transl_table=11
                     /translation="MNPSDQPRAVAALLPAAPLQDHPGGDSRGVLNVVGVHLYLERDGR
                     VLLGLRHPDSAFAARTHHFLAGHCERESAVACLVREAEEEAGLGIDPAYVELVHLVHVV
                     HGPGDRPRMQLVFRARAWTGTPEVREPDRCLSWDWWPADALPDRVVPYTRAAIEGIRAG
                     RLYTELGW"
     gene            10218..10820
                     /locus_tag="C0216_RS16300"
                     /old_locus_tag="C0216_16275"
     CDS             10218..10820
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891015.1"
                     /locus_tag="C0216_RS16300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16275"
                     /product="VanZ family protein"
                     /protein_id="WP_174250409.1"
                     /transl_table=11
                     /translation="MGIRRKFAGSRPWAGPPPRTAPGRRPVVRALAVAAAFAGTVLFSL
                     ALARVTLEPSAASAGLVHSNVHPGASIRQYLEQGSAGDAARQLGGNLLLGVPFGLLLPV
                     MVPQTRGLLRVAAVTAVVMTLVELVQGALVTGRAFDVDDVLLNTAGALLGFLLAGRRMS
                     RAVHPRRRRWWHRLPGFGPRGGARAPEAGGGGAGPPA"
     gene            10947..11204
                     /locus_tag="C0216_RS16305"
                     /old_locus_tag="C0216_16280"
     CDS             10947..11204
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (7-58). E-value:
                     0.0017. Score: 11.2. Matches aSDomain:
                     nrpspksdomains_C0216_RS16305_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025715.4"
                     /locus_tag="C0216_RS16305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16280"
                     /product="DUF4404 family protein"
                     /protein_id="WP_114055988.1"
                     /transl_table=11
                     /translation="MPNRPAGDHLEGLRARVAAGGEHGLTPAEHEELQRLLDRAGRDGA
                     RDDPGLAESLEEAALRFEARHPSVSAALRTVGVNLANLGI"
     aSDomain        10968..11120
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16305_PKS_Docking_Cterm.
                     1"
                     /evalue="1.70E-03"
                     /label="C0216_RS16305_PKS_Docking_Cterm.1"
                     /locus_tag="C0216_RS16305"
                     /protein_end="58"
                     /protein_start="7"
                     /score="11.2"
                     /tool="antismash"
                     /translation="DHLEGLRARVAAGGEHGLTPAEHEELQRLLDRAGRDGARDDPGLA
                     ESLEEA"
     gene            11273..12622
                     /locus_tag="C0216_RS16310"
                     /old_locus_tag="C0216_16285"
     CDS             11273..12622
                     /EC_number="1.6.5.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044538.1"
                     /locus_tag="C0216_RS16310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16285"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_114055989.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.4e-51, bitscore:
                     171.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARPRILVVGAGFAGVECVRRLERRLMPGEADITVVTPNSYQLYL
                     PLLPQVASGVLTPQSVAVSLRRSERNRTRILPGTAVGVDPAAKVCVVRTISGDLTDRPY
                     DHLVLAPGSVTRTFDIPGLAEHARGMKTLAEAAYLRDHVIAQLDLADACGDPAEQDGRL
                     RFVVVGGGYAGTETAACLQRLTTHAVERYPRLEARRISWHLVDLAPRLMPELGDALGRA
                     ALDVLRRRGIEVSLGVSVAKAGAAEVTLTDGRVLPTRTLIWTAGVAASPLVATLGTPTE
                     RGRLAVTPDMAVPGAPGVFALGDAAAVPDLVQGTEGAVCPPTAQHASRQGRTVADNVIA
                     ALRGQPLRPYRHRDLGLVVDLGGTDAVSKPLGVPLRGLPAQAVARGYHWGALRTGVAKT
                     RVLTNWLLNAVAGDDFVRTGFQERRPATLREFEQTDAYLTAEEIRARTAR"
     gene            complement(12672..14096)
                     /locus_tag="C0216_RS16315"
                     /old_locus_tag="C0216_16290"
     CDS             complement(12672..14096)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003956886.1"
                     /locus_tag="C0216_RS16315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16290"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_114055990.1"
                     /transl_table=11
                     /translation="MTRTSLPAPAGLLRRILGEQRIGLVAWRLLVLQTAHPAVAAGTAH
                     YSTYRAHPWRRIQHTMDSGTRLFFAGPEDRERETARLARTHRRIRGTDDAGRPYTAEDP
                     EVRAWVMVTLYEAMTAMRTLSGDPLTAVELDTLYAEFKEVCAALDIPAESLPPTAADVP
                     AYVDRTVREVLEYGEQVRYLLFDMLREAPAPRRLGRLRPLWPLLRAVAARTLTALTVAD
                     LPPAWHERFGTPRPRSAAALSWAVHRGMRQITTLLPDRVRYRHHPDGGTGARPARQGRP
                     RRAVPALRLPRPRTADSRPARLEAFFRQVLDQTGDGRVNSADLQAMVHNVCWQLELPAE
                     QEDVLYAAFESWWRHLCAGTDADGDGGVDCAEFVTAMLTGLDRDPDYLEKGLVPAMRAL
                     FRAADTDGSGHLCADEYRTLFGGKRIHPAELNHGFRQLDADGDGRVAEAEFVAAFTDFF
                     TARTDSAAGTALLGRP"
     gene            complement(14228..14881)
                     /locus_tag="C0216_RS16320"
                     /old_locus_tag="C0216_16295"
     CDS             complement(14228..14881)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007460550.1"
                     /locus_tag="C0216_RS16320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16295"
                     /product="hypothetical protein"
                     /protein_id="WP_246042575.1"
                     /transl_table=11
                     /translation="MTAHPPTPEQPPTPAGDPRPGTSAAPAAAAPGRFTGCGAALLAAA
                     VLACLGLVGLHELERGIDGYGQLEETSGADGGVADPLAAGRTARYEDGLKVTVGAPRRG
                     ADGTHLITVTYRNDTDGEQRIGGDSAETAVSEYGEAPLVVRAGRSLDRHTSGGVRWSNR
                     GESAAALLPPLAEDGKRTVPVRLTADRTGTTVTVEVRPPDDGYREAAYWEFTLD"
     gene            15199..15843
                     /locus_tag="C0216_RS16325"
                     /old_locus_tag="C0216_16300"
     CDS             15199..15843
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014818415.1"
                     /locus_tag="C0216_RS16325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16300"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_114055991.1"
                     /transl_table=11
                     /translation="MAQLLRVQNFNVSSDGIGAGEDQTLERPFGRVDPGRMFAWAGATA
                     SWPNRTEPGGSRGLDDYFTRDFTHNIGAEIMGRNKFGPQRGPWQDHAWRGWWGDEPPFR
                     TPVFVLTHHPRPSFTLSDTTFHFVSGEPAAVLDLAREAARGKDVRLGGGVRTIREFLDA
                     DLVDTLHVAVSPVELGSGLKLWDSPQDLLDRFHLETVPSPSGVVHHLFWRR"
     gene            complement(15884..18559)
                     /locus_tag="C0216_RS16330"
                     /old_locus_tag="C0216_16305"
     CDS             complement(15884..18559)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS16330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C0216_16305"
                     /product="hypothetical protein"
                     /protein_id="WP_162793238.1"
                     /transl_table=11
                     /translation="MTGRAGPRPRGPQRPDPAAAAPGLRVWAQLMRRVHDELYEAREPA
                     DRPTVTALARAANLSPPYVSESFSGKRRPRLAPFLSMVTALGGDPREWEPRWHRAWAEQ
                     DPAPCEDPAAGGAPAPDRAAVPSARPAALPGVDDDDRAPAPAPPGDAPAAALRRYPVRR
                     LLRAVAAWLLAVLAWPARSRRDAYAAQLRRRLVKQVRDRTAVELGRAEAHHYLTPRFAI
                     LTAPEHDRSHAGRARRSRRARRAEPVAVPAQAATLRALYEDTDDLVLLGRPGMGKTTQL
                     AALAHRLAVEALDTPDTPDAPDAPCDRSAGHVPVYLRLDTYRGEPVEEWLAAAMAQQYR
                     GVSGILVRTWLQEHRLVPVLDGLDEVPEPERSRCVAELRRLRRSCPGMAVGCRTDEADL
                     RRLAQDLRALRYVEVLPPSRRDVQDFLAADRGALADVHAALEGDPDLWPLFQSPMMLNF
                     IRLTYRYRPADDLRAPGSLAERRGRILDAYTRECLRRERPRPDADPERTLTWLASLARM
                     LTARKEHVLYLDRLDLTWLTPAEQVLPRIVPNVVMAVAALGLPVVWLAAAVPAGMLDTS
                     VRDAAALAAAMAVNVAAQAYQSEKHHLARGGGPRVEQRGAVAAPMAANAPAMVLILCWL
                     VFVVEADLTAPGCWIVGLAYAWVALTQLEASFTPVFQPVEQMRWTWFRQELMIYSSPLK
                     YHLARGLLSGLVSVALICLLGYVVLLLCPQPAWIAPAAAVFLGFLYAFGNQFEPSLQDR
                     RPRPNEGVRRSVRFCLVHGLAGLAAAGLGLLALITAAAPGGDSLRRAAFAAALLGGQFA
                     VIRGFRFGGLAVVHHWTVRAVLAQRGRTPYRYRRFLDAAEQRVLLHRTDSGYFFPHRLL
                     QLHLDAAPEDLLPRLLPPPP"
     gene            18823..19143
                     /locus_tag="C0216_RS16335"
                     /old_locus_tag="C0216_16310"
     CDS             18823..19143
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS16335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C0216_16310"
                     /product="hypothetical protein"
                     /protein_id="WP_114055993.1"
                     /transl_table=11
                     /translation="MSLHTTVTRVLPSLGGLAAAGAGVLADAPWWLVGVLGFAALLVLR
                     AEALVNARNEARRGSHEHRLLATVSGRQALDYLTEVRRAQAGPAAAPGPGAEGGAAGGG
                     TA"
     gene            19417..19608
                     /locus_tag="C0216_RS16340"
                     /old_locus_tag="C0216_16315"
     CDS             19417..19608
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039421.3"
                     /locus_tag="C0216_RS16340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16315"
                     /product="DUF6381 family protein"
                     /protein_id="WP_114055994.1"
                     /transl_table=11
                     /translation="MSDGKQPGEPTARRMREEAEELELAAQHASDPEERRRLTDEALRI
                     RERIERESGPEGATMDPM"
     misc_feature    complement(19850..19867)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.45"
                     /tool="antismash"
     misc_feature    19853..19867
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.52"
                     /tool="antismash"
     misc_feature    complement(19861..19878)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 13.55"
                     /tool="antismash"
     misc_feature    19900..19914
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.29"
                     /tool="antismash"
     misc_feature    19986..20000
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.36"
                     /tool="antismash"
     misc_feature    complement(19990..20003)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 11.94"
                     /tool="antismash"
     misc_feature    19994..20007
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 11.63"
                     /tool="antismash"
     gene            20001..27131
                     /locus_tag="C0216_RS16345"
                     /old_locus_tag="C0216_16320"
     CDS             20001..27131
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (683-1124). E-value:
                     3.7e-122. Score: 400.2. Matches aSDomain:
                     nrpspksdomains_C0216_RS16345_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1249-1543). E-value: 1.6e-59.
                     Score: 193.7. Matches aSDomain:
                     nrpspksdomains_C0216_RS16345_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (1733-1779). E-value: 2e-07.
                     Score: 23.2. Matches aSDomain:
                     nrpspksdomains_C0216_RS16345_PP-binding.1"
                     /NRPS_PKS="Domain: PKS_KR (2096-2321). E-value: 3.8e-37.
                     Score: 119.9. Matches aSDomain:
                     nrpspksdomains_C0216_RS16345_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hglE-KS: hglE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127427.1"
                     /locus_tag="C0216_RS16345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16320"
                     /product="type I polyketide synthase"
                     /protein_id="WP_114055995.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.3e-69, bitscore:
                     232.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="hglE (E-value: 1.2e-123, bitscore: 411.2,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.6e-57, bitscore: 193.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.9e-05, bitscore:
                     22.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPAEHVIGVTPFGEPDARLAAAVTRGGGLGVLDLGSGDRAARAA
                     LADLRGWLPGRFGVRVGPRCRLRPGDAAGLLGGPGGPRTVLLAEGSAVRPADVPPGVRV
                     LAEATGLAEARAALDAGAHGLVARGSECGGRIGELGTFVLLQQLLDAAGPDGPPVWACG
                     GIAPGTAAAAVAGGAAGVVLDTQLALLAESALPAAVAAVLRPLDGSETTELGGHRFLHR
                     RRAAAPPPGAPPLDLPDDPDRIASLLGGRDPDTQLLPVGQDAPLAAVFADRHRDAAGAV
                     RAVAEAVRAATADGAAGRALAAGSPMSRALGTRLPIAQGPMTRVSDGADFARAVSDGGA
                     LPFLALALAGREQAAALLAEAAAALDGRPWGVGVLGFAPEETRAAQLEAVRAHRPSHAV
                     IAGGRPSQARALEADGIRTFLHAPSPGLLRQYLAEGARRFVFEGAECGGHVGPRNSFPL
                     WEAQTRVLLDHLAGDPGAAPALEVFFAGGVHDARSAAMVAALAAPLSARGCAVGVLMGT
                     AYLFTREAVAHGAVRPLFQRQVLAAERTALLRTAPGHATRCVPSPFSEGFRMLAAELRA
                     GGAPEREVWERLERLNVGRLRLASKGVERTAAGTTAPVDEERQYAEGMFMAGQAAVLRD
                     CATTVAELHESVTAGAAAFLERRRAALRAAAPDRAGAGSGGRAPAPLDIAVVGMACVFP
                     GAPDLAAFWAQVLDGRDAVTEVPAERWDPDVHCSPGPDGSGPASASRWGGFLPRIPFDP
                     LRYGIPPASLGSIEPVQLLALEVSRRALEDAGRGEGGRPFDRARTGVVFGTEAGSDLSN
                     AATLRTVLPSYYGRVPAGLDGQLPRLTEDTFPGVLANVVAGRVANRLDLRGPNHTVDAA
                     CASSLAALDAACKELVLGTSDMMLCGGADLHNGINDYALFTSVRALSPTGRSRAFDRSA
                     DGIALGEGVACVVLKRLADAERDGDRVYAVVKAVGASSDGRSLGLTAPRPEGQRAALER
                     AYRGSGVSPADVGLVEAHGTGTVVGDRTELRVLTEVFEAAGARAGSCVLGSVKSQIGHT
                     KCAAGLAGLVKTALALHTGVRPPTLHLSRPDPAWQAGASPFVFHREALPWPAAPGRRYA
                     GLSAFGFGGTNFHAVLAGHDAGGPPPEHTRDEWPAELFLFRGTDTAAARRAAADLLEAA
                     DAAARGETPWRLRDLAATAAGRAARARGGIRIAFTARDLAELCRLLRAAADGAGADAAA
                     GAAPGGRVYRAEGDGAGGAGRTVFLFPGQGSQRPGMSAHLFTAFPGLGRLLRADAGGRA
                     AAALYPPAAFDDAAREEMRRALTDTRAAQPALGMVELAAYELLARCGIRPDMAAGHSYG
                     ELVALCAAGVVDAEALPRLSSARAAAILDAVGADPGAMAAVAAAPEDIGRVLGGPPLPG
                     GLVVANHNAPRQCVLSGPTPAVEAAVRRLGEAGLGVKRLPVACAFHSPLVAAAGQPFGR
                     ALAEQHLHEPEFEVWANRTARPYPAGPDAVRGELAAQIGAPVRFAEQIEAMYAAGARTF
                     VEVGPGCVLTRLVSDVLAGRPHRTVACEPRPDSGLAGFLDAVARLAAAGLPVAADWMFR
                     GRDAVDTDRAPAPRTPGWTVDGHLVRTASGDPLPGALAPARPVVEAPVATNPGEAAPGA
                     PDALVAEFLRSSREVIAAQRDVLLAYFGGTVEAAPGAAGPQSLPLPVPLPVPVPLPEYG
                     SGQAAAAGADRGRIGRGPARDAAAERAAGDGETILRTVLELIAERTGYPLDMVEPDLDL
                     ESDLSVDSIKRAEIAGELARRLAPADAAGPMALDDAELEELARARTATAIAAWLAARAT
                     ATAPADAPGPAPGPGSGAAEEPGAGPGAGHPVDDALADAPAAAAGAVTAAGARAAAGAT
                     PDPVGAAPRRYRVVQAEVVGPRPGPPDLAGSRWAVLGDGAGAWRGTAARLAAVLDAQGA
                     LRVDPGEGGDGLAVADGALDGVVVLDALGEAGGRAFLPDGFGVVRAVLRAGARRLFVVR
                     EAGYGLRAAGVDGLVRAAAREYPDAVVRCVVLGADAAPGPEGAVEALLEEAAAGGGEPV
                     VLRTPAGRFAPVLVEAPLGPLAGRGAGPAGAGAAEAEALGLDRDAVLVVVGGARGITAR
                     CVAVIAAAARCRVEILGRTPVPAGPEEALTAAAADRADLRGVLAGTGRYASPADVERAA
                     GLVLARREVAATLDAVMAAGGLARYRSVDCRDAAAVLQAVKEIHAEHGRIDGVVHGAGI
                     VEDRLIADKSPESFRRVHGTKTLSAAALLAAVEQLPEGERPRFAVLFGSIAAVLGNRGQ
                     TDYAAANDALEAYGAAWAARTGLRALTVHWGPWAPSPVHGGMVAPELARHYARRGVRLI
                     DPEEGAQALLRELAWGDPAERAVVLSASEW"
     misc_feature    20199..20201
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        22050..23372
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16345_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="3.70E-122"
                     /label="C0216_RS16345_PKS_KS.1"
                     /locus_tag="C0216_RS16345"
                     /protein_end="1124"
                     /protein_start="683"
                     /score="400.2"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="IAVVGMACVFPGAPDLAAFWAQVLDGRDAVTEVPAERWDPDVHCS
                     PGPDGSGPASASRWGGFLPRIPFDPLRYGIPPASLGSIEPVQLLALEVSRRALEDAGRG
                     EGGRPFDRARTGVVFGTEAGSDLSNAATLRTVLPSYYGRVPAGLDGQLPRLTEDTFPGV
                     LANVVAGRVANRLDLRGPNHTVDAACASSLAALDAACKELVLGTSDMMLCGGADLHNGI
                     NDYALFTSVRALSPTGRSRAFDRSADGIALGEGVACVVLKRLADAERDGDRVYAVVKAV
                     GASSDGRSLGLTAPRPEGQRAALERAYRGSGVSPADVGLVEAHGTGTVVGDRTELRVLT
                     EVFEAAGARAGSCVLGSVKSQIGHTKCAAGLAGLVKTALALHTGVRPPTLHLSRPDPAW
                     QAGASPFVFHREALPWPAAPGRRYAGLSAFGFGGTNFHAVLA"
     aSModule        22050..25337
                     /complete
                     /domains="nrpspksdomains_C0216_RS16345_PKS_KS.1"
                     /domains="nrpspksdomains_C0216_RS16345_PKS_AT.1"
                     /domains="nrpspksdomains_C0216_RS16345_PP-binding.1"
                     /locus_tags="C0216_RS16345"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       22587..22634
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C0216_RS16345_0001"
                     /evalue="2.20E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="C0216_RS16345"
                     /protein_end="878"
                     /protein_start="862"
                     /score="13.7"
                     /tool="antismash"
                     /translation="GPNHTVDAACASSLAA"
     CDS_motif       23010..23054
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C0216_RS16345_0002"
                     /evalue="3.00E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="C0216_RS16345"
                     /protein_end="1018"
                     /protein_start="1003"
                     /score="10.3"
                     /tool="antismash"
                     /translation="VEAHGTGTVVGDRTE"
     CDS_motif       23115..23159
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C0216_RS16345_0003"
                     /evalue="6.60E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="C0216_RS16345"
                     /protein_end="1053"
                     /protein_start="1038"
                     /score="9.4"
                     /tool="antismash"
                     /translation="GSVKSQIGHTKCAAG"
     CDS_motif       23742..23795
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C0216_RS16345_0004"
                     /evalue="2.60E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="C0216_RS16345"
                     /protein_end="1265"
                     /protein_start="1247"
                     /score="19.7"
                     /tool="antismash"
                     /translation="VFLFPGQGSQRPGMSAHL"
     aSDomain        23748..24629
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16345_PKS_AT.1"
                     /evalue="1.60E-59"
                     /label="C0216_RS16345_PKS_AT.1"
                     /locus_tag="C0216_RS16345"
                     /protein_end="1543"
                     /protein_start="1249"
                     /score="193.7"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFPGQGSQRPGMSAHLFTAFPGLGRLLRADAGGRAAAALYPPAAF
                     DDAAREEMRRALTDTRAAQPALGMVELAAYELLARCGIRPDMAAGHSYGELVALCAAGV
                     VDAEALPRLSSARAAAILDAVGADPGAMAAVAAAPEDIGRVLGGPPLPGGLVVANHNAP
                     RQCVLSGPTPAVEAAVRRLGEAGLGVKRLPVACAFHSPLVAAAGQPFGRALAEQHLHEP
                     EFEVWANRTARPYPAGPDAVRGELAAQIGAPVRFAEQIEAMYAAGARTFVEVGPGCVLT
                     RLVSDVLAGRPHR"
     CDS_motif       23991..24071
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C0216_RS16345_0005"
                     /evalue="1.70E-09"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="C0216_RS16345"
                     /protein_end="1357"
                     /protein_start="1330"
                     /score="29.6"
                     /tool="antismash"
                     /translation="GIRPDMAAGHSYGELVALCAAGVVDAE"
     aSDomain        25200..25337
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16345_PP-binding.1"
                     /evalue="2.00E-07"
                     /label="C0216_RS16345_PP-binding.1"
                     /locus_tag="C0216_RS16345"
                     /protein_end="1779"
                     /protein_start="1733"
                     /score="23.2"
                     /tool="antismash"
                     /translation="TVLELIAERTGYPLDMVEPDLDLESDLSVDSIKRAEIAGELARRL
                     A"
     aSDomain        26289..26963
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16345_PKS_KR.1"
                     /evalue="3.80E-37"
                     /label="C0216_RS16345_PKS_KR.1"
                     /locus_tag="C0216_RS16345"
                     /protein_end="2321"
                     /protein_start="2096"
                     /score="119.9"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="VLVVVGGARGITARCVAVIAAAARCRVEILGRTPVPAGPEEALTA
                     AAADRADLRGVLAGTGRYASPADVERAAGLVLARREVAATLDAVMAAGGLARYRSVDCR
                     DAAAVLQAVKEIHAEHGRIDGVVHGAGIVEDRLIADKSPESFRRVHGTKTLSAAALLAA
                     VEQLPEGERPRFAVLFGSIAAVLGNRGQTDYAAANDALEAYGAAWAARTGLRALTVHWG
                     PWA"
     CDS_motif       26808..26909
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C0216_RS16345_0006"
                     /evalue="9.70E-14"
                     /label="PKSI-KR_m4"
                     /locus_tag="C0216_RS16345"
                     /protein_end="2303"
                     /protein_start="2269"
                     /score="43.9"
                     /tool="antismash"
                     /translation="RFAVLFGSIAAVLGNRGQTDYAAANDALEAYGAA"
     aSDomain        27200..28585
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16350_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="3.10E-108"
                     /label="C0216_RS16350_PKS_KS.1"
                     /locus_tag="C0216_RS16350"
                     /protein_end="462"
                     /protein_start="0"
                     /score="354.3"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="MSVLLPGTPDLAAYWRHLCAGADLVGEVPPGRWDAAYYHPGSAPE
                     AAAADRVYCRRGGFVDAVAEVDPTRLGVMPSSVPATEPDQLIALHVAANALADAGGPGR
                     LPDRERVGIVLGRGGYLTPGLVRLDQRVRTARQLVCTLAELLPGLDADRLEEVRRAFTE
                     RLGPDRPEDAIGLVPNLAASRVANRLDLRGPAYTVDAACASSLLAVDQAVSALADGRCD
                     VMLAGGVHHCHDITLWSVFSQLRALSPSERIRPFHRGADGLLIGEGTGVVVLKRLADAE
                     RDGDRVYAVVRGTGVSSDGRASGLVNPDPAGQARAVRAAWRAAGLDPAAPGSLGLLEAH
                     GTATPAGDAAELATLQQVFGPPDTSQGAGRPVLGSVKSMIGHAMPAAGIAGLVKAALAV
                     YHGVLLPTLHCEDPHPALARTRFRPLAQAAPWEEGPGGGPRRAGVNAFGFGGINAHVVL
                     EQAP"
     gene            27200..31792
                     /locus_tag="C0216_RS16350"
                     /old_locus_tag="C0216_16325"
     CDS             27200..31792
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (0-462). E-value:
                     3.1e-108. Score: 354.3. Matches aSDomain:
                     nrpspksdomains_C0216_RS16350_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (624-844). E-value: 8.5e-37.
                     Score: 119.0. Matches aSDomain:
                     nrpspksdomains_C0216_RS16350_PKS_AT.1"
                     /NRPS_PKS="Domain: ACPS (1383-1445). E-value: 9.2e-08.
                     Score: 23.9. Matches aSDomain:
                     nrpspksdomains_C0216_RS16350_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058250.1"
                     /locus_tag="C0216_RS16350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16325"
                     /product="type I polyketide synthase"
                     /protein_id="WP_246042829.1"
                     /sec_met_domain="PKS_KS (E-value: 3.1e-106, bitscore:
                     354.3, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.5e-57, bitscore:
                     192.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 8.6e-35, bitscore: 119.0,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVLLPGTPDLAAYWRHLCAGADLVGEVPPGRWDAAYYHPGSAPE
                     AAAADRVYCRRGGFVDAVAEVDPTRLGVMPSSVPATEPDQLIALHVAANALADAGGPGR
                     LPDRERVGIVLGRGGYLTPGLVRLDQRVRTARQLVCTLAELLPGLDADRLEEVRRAFTE
                     RLGPDRPEDAIGLVPNLAASRVANRLDLRGPAYTVDAACASSLLAVDQAVSALADGRCD
                     VMLAGGVHHCHDITLWSVFSQLRALSPSERIRPFHRGADGLLIGEGTGVVVLKRLADAE
                     RDGDRVYAVVRGTGVSSDGRASGLVNPDPAGQARAVRAAWRAAGLDPAAPGSLGLLEAH
                     GTATPAGDAAELATLQQVFGPPDTSQGAGRPVLGSVKSMIGHAMPAAGIAGLVKAALAV
                     YHGVLLPTLHCEDPHPALARTRFRPLAQAAPWEEGPGGGPRRAGVNAFGFGGINAHVVL
                     EQAPASAPAAALPLPPGPRARTAVDEPERVLLLAAETPGGLARLLDAPDPAVHAEGQAA
                     APAKPVRLAVVGPSAERLALARRAVAKGAPWHGRGDVWFRPGPLLGAASPGPGRTVFLF
                     PGLEAEFAPRVDEVADRFGLPRPPAPPGPAADGPAAVGGLGRHGLGVVAVGRLLDAALR
                     RIGAVPDAVAGHSVGEWTAMAAGGLYEEEAVDAFMAALDPEAVRAADLAYAAVGAHADR
                     VAERLAGGGHPGVVVSHDNAPGQCMVCGPPDAVGRFAAEVRAGGVLVRTLPFRSGFHTP
                     MLAPCIGPFREAAERLPLRTPHTPVWSGTTGRPFPADAAGVRELFVRHLLEPVRFRVLT
                     GSLYEAGFRVFVQVGPGQLGSLVGDTLAARDHLVVAANSARRGGLAQLRRVAAALWTAG
                     AATDPEAVDGRDAGPERTARPGAAGARTGRPVRLDLGAALVSLPPSARPPLAPHPSPSA
                     VAAAASAAGGPVAAELAALLDETARTAQTAAALLAGAGRPGTRVRRRAPAAPAARRETV
                     RVSVEHMPYLLDHCFFPQRADWPDVADRWPVVPATTITALMKAAAERAAPGRAAVAVHD
                     ACFDRWLTAAEPVDVPVSVAPCGPDRVAVSFGPHARAVVELAGRWPAEPPPAVPADPAG
                     ERVPDHTAEEVYRERWMFHGPAYRGMSRLTAIGDRHVRAVLTVPPAPGGLLDNVGQVLG
                     YWIMATRTERTVVFPVRVRQMRFHGPDPRPGTRVECTVRITSLTDTVLEADAVLTVAGR
                     VWAELSGWQDRRFDNDPHTRPVERFPDRNTLSVAGPGGWSLVFERWPDLASRELIMRNA
                     LGGPERAAYAARPPRGRRQWLLGRIAAKDAVRRLLWEAGEGPVFPAELLVENEPSGRPR
                     VTGRYGRTLPPLRVSVAHRAEAGVALARAADAPVGPGPGPGIDIEEIAEPGGATAATVF
                     GAAELALLAACRAGSAEPADVWFTRFWAAKEAVAKAEGTGLRGRPRDIEVTAAEPDRLT
                     VRVRRRTDAADPPGAPGPPGGPYGVYRVGCTEVANPPGLPPRAYVVAWTTGPDPDPPGP
                     GADRDEGSEG"
     aSModule        27200..32052
                     /complete
                     /domains="nrpspksdomains_C0216_RS16350_PKS_KS.1"
                     /domains="nrpspksdomains_C0216_RS16350_PKS_AT.1"
                     /domains="nrpspksdomains_C0216_RS16350_ACPS.1"
                     /domains="nrpspksdomains_C0216_RS16355_PP-binding.1"
                     /locus_tags="C0216_RS16350"
                     /locus_tags="C0216_RS16355"
                     /monomer_pairings="mal -> mal"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       27776..27823
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C0216_RS16350_0001"
                     /evalue="4.00E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="C0216_RS16350"
                     /protein_end="208"
                     /protein_start="192"
                     /score="15.9"
                     /tool="antismash"
                     /translation="GPAYTVDAACASSLLA"
     aSDomain        29072..29731
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16350_PKS_AT.1"
                     /evalue="8.50E-37"
                     /label="C0216_RS16350_PKS_AT.1"
                     /locus_tag="C0216_RS16350"
                     /protein_end="844"
                     /protein_start="624"
                     /score="119.0"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: (unknown)"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="AVGRLLDAALRRIGAVPDAVAGHSVGEWTAMAAGGLYEEEAVDAF
                     MAALDPEAVRAADLAYAAVGAHADRVAERLAGGGHPGVVVSHDNAPGQCMVCGPPDAVG
                     RFAAEVRAGGVLVRTLPFRSGFHTPMLAPCIGPFREAAERLPLRTPHTPVWSGTTGRPF
                     PADAAGVRELFVRHLLEPVRFRVLTGSLYEAGFRVFVQVGPGQLGSLVGDTLAARDH"
     CDS_motif       29111..29185
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C0216_RS16350_0002"
                     /evalue="8.90E-08"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="C0216_RS16350"
                     /protein_end="662"
                     /protein_start="637"
                     /score="24.1"
                     /tool="antismash"
                     /translation="GAVPDAVAGHSVGEWTAMAAGGLYE"
     aSDomain        31349..31534
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16350_ACPS.1"
                     /evalue="9.20E-08"
                     /label="C0216_RS16350_ACPS.1"
                     /locus_tag="C0216_RS16350"
                     /protein_end="1445"
                     /protein_start="1383"
                     /score="23.9"
                     /tool="antismash"
                     /translation="GIDIEEIAEPGGATAATVFGAAELALLAACRAGSAEPADVWFTRF
                     WAAKEAVAKAEGTGLRG"
     gene            31861..32124
                     /locus_tag="C0216_RS16355"
                     /old_locus_tag="C0216_16330"
     CDS             31861..32124
                     /NRPS_PKS="Domain: PP-binding (11-64). E-value: 3.4e-07.
                     Score: 22.5. Matches aSDomain:
                     nrpspksdomains_C0216_RS16355_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173581.1"
                     /locus_tag="C0216_RS16355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16330"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_114058711.1"
                     /sec_met_domain="PP-binding (E-value: 1.2e-05, bitscore:
                     24.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRQVLEGYEVEEGEVTMRTRFGADLELESIDLVTLAGLLEERYG
                     GAVNFAEFVADLDLEEIIELDVGRLVDHIRRCLKAADGVGTR"
     aSDomain        31894..32052
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16355_PP-binding.1"
                     /evalue="3.40E-07"
                     /label="C0216_RS16355_PP-binding.1"
                     /locus_tag="C0216_RS16355"
                     /protein_end="64"
                     /protein_start="11"
                     /score="22.5"
                     /tool="antismash"
                     /translation="EEGEVTMRTRFGADLELESIDLVTLAGLLEERYGGAVNFAEFVAD
                     LDLEEIIE"
     gene            32121..32969
                     /locus_tag="C0216_RS16360"
                     /old_locus_tag="C0216_16335"
     CDS             32121..32969
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (26-143). E-value:
                     1.3e-29. Score: 95.4. Matches aSDomain:
                     nrpspksdomains_C0216_RS16360_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062829.1"
                     /locus_tag="C0216_RS16360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16335"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_114055996.1"
                     /sec_met_domain="PF00561 (E-value: 4.5e-25, bitscore: 87.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.6e-19, bitscore:
                     68.4, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2.5e-07, bitscore:
                     29.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVLDTGRVRLHVQRLAPPDGRPARATVVLVHGLLTDSLASYYFT
                     IAPALAAAGLDVVMYDQRGHGRSERPARGYGLDDAAGDLDAVLSGLGVRGPVHLVGNSY
                     GGTVAFAYALRRPERVAGLVVVESEPATAAWAAKLAGLLERVRHEMTADEDAALAWIAA
                     HHGGHTARLARAAGRLVRDTSIAVDIPASPVLDDDAIRALRCPVLALYGAESDLAGQAP
                     RLRALLPHCTAELVPGLRHSVLVEAPARVRDAVLDWVGRTTAPAAAERQPAAAGPRVHA
                     R"
     aSDomain        32199..32549
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16360_Abhydrolase_1.1"
                     /evalue="1.30E-29"
                     /label="C0216_RS16360_Abhydrolase_1.1"
                     /locus_tag="C0216_RS16360"
                     /protein_end="143"
                     /protein_start="26"
                     /score="95.4"
                     /tool="antismash"
                     /translation="TVVLVHGLLTDSLASYYFTIAPALAAAGLDVVMYDQRGHGRSERP
                     ARGYGLDDAAGDLDAVLSGLGVRGPVHLVGNSYGGTVAFAYALRRPERVAGLVVVESEP
                     ATAAWAAKLAGLL"
     CDS_motif       32400..32459
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C0216_RS16360_0001"
                     /evalue="9.80E-07"
                     /label="NRPS-te1"
                     /locus_tag="C0216_RS16360"
                     /protein_end="113"
                     /protein_start="93"
                     /score="21.3"
                     /tool="antismash"
                     /translation="RGPVHLVGNSYGGTVAFAYA"
     gene            32966..34186
                     /locus_tag="C0216_RS16365"
                     /old_locus_tag="C0216_16340"
     CDS             32966..34186
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062830.1"
                     /locus_tag="C0216_RS16365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16340"
                     /product="glycosyltransferase"
                     /protein_id="WP_114055997.1"
                     /sec_met_domain="MGT (E-value: 1.3e-39, bitscore: 135.1,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAFLLVVPPLVGHVNPLVGVASELAARGHRVAWAGDPVLVRRLA
                     GPDAAVHPCARSGPEDGGGGGGGGTDPVRPPGMRGPEALRFLWERFLVPLAEAMAPGVR
                     EAVGAFRPDAVVADQQALAGALVAEDLGIPWATSATTSAEFADALAPMPRVAAWNDALL
                     SGLRRRIGRPGGRCDPRFSPHLVLAFSTPELAGPVLRGGERIAWVGPSLAARPRPAAFP
                     WERLDPGRALVLVTLGTANAGAGGRFLAEAAAAVRARAGAVQGVFADPDGVLGAREDDP
                     DVVALPFVPQLDLLERAAAAVCHAGHNTVCEALWHGVPLVVAPIRDDQPVVAAQVEGCG
                     AGVRVRFGRAGAAAIGAALDTVLGEPRIRAAAAGVSAAFRAAGGAAAAADHLERLARTG
                     AGEGEDG"
     gene            34183..35286
                     /locus_tag="C0216_RS16370"
                     /old_locus_tag="C0216_16345"
     CDS             34183..35286
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127422.1"
                     /locus_tag="C0216_RS16370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16345"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_174250411.1"
                     /transl_table=11
                     /translation="MSGRRERAARVAALRAVYREELADGTAVFFEPRAHRCPWCGSGRL
                     GGRLRTADLLQHKPGEFALDRCHDCGHVFQNPRLSERGLAFYYRDFYDGLGEERLAGVF
                     AGRTASYRARAESVRPHLAGPAEWLDVGTGHGHFCATAAELLPDVAFDGLDRSDGAELA
                     ELAGRVRHGHRGTFAELAEKAPGSYDVVSMFHYLEHAPDPLAELEAAYAVLRPGGLLVV
                     DVPDPESRWARLLGRWWLPWLQPQHLHLAPAGNLRRRLDACGFTVLAQEHAQAHDAVDL
                     VAAAWLALDAAAPREDLPWLPEPPGPARRALRGATLLAGVPLLLAATVLDRTVAGLAAE
                     RWGLTNAYRLVARREARPDAAPATAGG"
     gene            35395..36678
                     /locus_tag="C0216_RS16375"
                     /old_locus_tag="C0216_16350"
     CDS             35395..36678
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS16375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C0216_16350"
                     /product="hypothetical protein"
                     /protein_id="WP_114055998.1"
                     /transl_table=11
                     /translation="MGTSVEGQVDMAGPVGKLLHRRRLHNSTVMQSFGVDPVTGDVFVL
                     QVVEGGLTLPGESGPRTGRQRAYAGDLAVTRLDQAGTVTGHMYLRGFGHGVSMGVEHDG
                     GVSRLWTETASVPMGSNMPEEEKDGYGTAVTHFEFRSGTTLSQGSAQLAPAYRPVSGAT
                     NVTCTIDPTTNRVIVRFKSGGMVFESYDLDRARAGDWTPVARIAQPDAKGTFQGYASLG
                     RVLYMVAGSGYSDTVKPPGNTWLTAVDWTDGSVLDQRFTTAAPGLELREPEGMAVSVRG
                     GVPHVHVGFAGEEPGPRTCTIVSLSGAPEVGGVKVLADWQPIPLASGVTADVRPPRGRL
                     VAIAGTTVLQLSGGVKGTFEADTLIGRLPDALAPSMAAQCSVPRNNSGGVCTARAEANS
                     IRELWLYGGRTANPVTWAQLDNYSAVWR"
     gene            36776..37225
                     /locus_tag="C0216_RS16380"
                     /old_locus_tag="C0216_16355"
     CDS             36776..37225
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS16380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C0216_16355"
                     /product="hypothetical protein"
                     /protein_id="WP_114055999.1"
                     /transl_table=11
                     /translation="MTHNRRRILGAALALPAALTAAEVLSAAPAVAAGGVEAQPWTDLV
                     LEPGVTARAGAVPQVRLVTIAGTAFLQARGSVACSLTADRKVATLPAALRPTGLVRATA
                     PRNNSQGINACRFEVNTAGSLTIYGGNSGNPITWVQFDSVQTVWH"
     gene            complement(37251..38135)
                     /locus_tag="C0216_RS16385"
                     /old_locus_tag="C0216_16360"
     CDS             complement(37251..38135)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656098.1"
                     /locus_tag="C0216_RS16385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16360"
                     /product="nuclease"
                     /protein_id="WP_114056000.1"
                     /transl_table=11
                     /translation="MSMLLIRGRFKVEGGPKPDGDTLPFIPDDVADWKLVPGGQVVPGA
                     DGRASIRLEGIDALETHYGQEPAPVDHQPRPLAHEAADELLKTLGFGTVLRDDDETLAT
                     VPDSVPGWILTRGADAYGRCVAFVGRGTPPVYSGYWTGVSARLLERTANHRLLERGLAY
                     PAFYSGLPVYLRELLTEAAEKARASAAGVWAVDRTLQGFPVTGKKSITHDREGAVILPK
                     LFRRLKDYLDFTGDPSPSADCFRAFLAGAADEYRLLPDTKRLYRGLHHIVEVTPDNIVR
                     MTRSCREIVFTEK"
     gene            complement(38361..39035)
                     /locus_tag="C0216_RS16390"
                     /old_locus_tag="C0216_16365"
     CDS             complement(38361..39035)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010033675.1"
                     /locus_tag="C0216_RS16390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16365"
                     /product="hypothetical protein"
                     /protein_id="WP_114056001.1"
                     /transl_table=11
                     /translation="MTTTRVKRHTARALSVALSACAVAAATALPAAAADQPTRKLLMAD
                     CRSGEGKCTFNSPKLGEAYLGEFRQVSNSLYNCSTSDATQSMTWDDTVGATDSLGVSVT
                     AGGNIAGLVDLSVTASYSHSWSSSHSESSSLNMTVKPGEVGWISRAQVMQKVTGTWQTH
                     YDSPKWGHYYWFFQDTITGPAKNGTDGKSNAVVVKTRKMTAAEKRSCKEGSSNGKAVVR
                     AL"
     misc_feature    complement(39136..39152)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.25"
                     /tool="antismash"
     gene            39316..40722
                     /locus_tag="C0216_RS16395"
                     /old_locus_tag="C0216_16370"
     CDS             39316..40722
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018560161.1"
                     /locus_tag="C0216_RS16395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16370"
                     /product="hypothetical protein"
                     /protein_id="WP_114056002.1"
                     /transl_table=11
                     /translation="MATHLPDDDSRLSLWLRVRRYAVPPSVIHTATARRSAGDWAGACA
                     AAGVDVDLHLPSVARTYGRDCAARLRADLRHLAPDLLRWHMPRTAPDGLLRPGLTVALA
                     RYAGTGPDGTGSLYLVVRTPPAWADAGQRIVLGLWDRSRPEAAPAARNHPHPRPARRFR
                     LDLHRHLWDARRAGELRHRSGADRPPGTAPAPALALPPGRSASAAPAYRCAPDLWPDEA
                     GLLLRADGLEPGPVEVRLGSRHRLVIDPATGRPAAAPAGGLRLPVLPDAAAWVPPDLEL
                     LRAGLIGPDRLHPLVAGALVPGHVPAGPPPGAEPDDGPRHVDCRGSRHRIGLVDGVLAA
                     LDHGPDELRREELLVALTGTPLPCLRAIDRAHRRPESLPGIRERLAHGDTAGALEAVES
                     LLGPGAVLRDGLLRDELESAARQRITYGLYRAGLVGPGPGRGPAGAGGEPPARRVRPSR
                     ARQRTSALFY"
     gene            40827..42077
                     /locus_tag="C0216_RS16400"
                     /old_locus_tag="C0216_16375"
     CDS             40827..42077
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612575.1"
                     /locus_tag="C0216_RS16400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16375"
                     /product="AAA family ATPase"
                     /protein_id="WP_114056003.1"
                     /transl_table=11
                     /translation="MPSTLSAPAPSAPAPAQLDVASELLALLRDTTTEPRPDVQLEALT
                     LAVAADLPVLLWGEPGIGKTAALTQLAENLGLPLTTVIASVHEPSDFSGLPVIGDDPAV
                     QGVPMAPPDWAVRLVRAGRGLLFLDELSTAPPAVQAALLRLVLERRIGSLRLPDGVRIV
                     AAANPRASAADGWELSPPLANRFVHLQWVHDHDVVVRGLGGTWPRATLPQLDPARLADA
                     VDLARRAVCGLLAGRPALVHRLPAGETRRGGAWPSPRSWEMTLRLIAFATAAGSSRDVL
                     SLLVRGAVGDGPGLELLAGLDRMDLPDPEDLLADPEAAVLPERGDLRQAVLDSVVAAVR
                     SRPEKSRWDAAWTLLVRAVESGAPDLVVVPATTLASLRRDAWDVPEAIEELAGVVALSR
                     RADRAAARTAPGAKAGR"
     gene            42074..43408
                     /locus_tag="C0216_RS16405"
                     /old_locus_tag="C0216_16380"
     CDS             42074..43408
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548394.1"
                     /locus_tag="C0216_RS16405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16380"
                     /product="VWA-like domain-containing protein"
                     /protein_id="WP_114056004.1"
                     /transl_table=11
                     /translation="MTGAADTADAAPGAGGPSEAEPGGAAPAAADSDGDSDRGLDLDKL
                     YAARLQAARARPYVATALYALHAVPSRQVPTMAVDRHWRCYVSPGFVDRTPVEELAAVW
                     VHEVSHLLRDHHGRSDRVARQQGLTGRAERLRMNIAADCEINDDAFGDGLVTPEGAVLP
                     ETLQLPEGQLMEDYLRQFRLGPQFGHLSWLDCGSGADGLDRQWDLGRDGAHGLSAQERD
                     AVRFRVAQGIKGRPGNAPRQWQRWAEEAFHPPQPWRDLLGAAIRSAVSGSGAGEDYSYG
                     RPSRRSSALRGTVLPSLRRRPPQVAVVIDTSGSVSDAELGGALLEVAAICRAVGGRRDL
                     VTVLTCDAAARVVGPLCRAEGIPLVGGGGTDLRRGFARALRSRPRPDVVVALTDGQTPW
                     PSDPPPCRTVVGLFPRPAPPGTPCEDDPDYRPDEPPQWARVVTLG"
     gene            43629..44552
                     /locus_tag="C0216_RS16410"
                     /old_locus_tag="C0216_16385"
     CDS             43629..44552
                     /NRPS_PKS="Domain: PKS_KR (19-193). E-value: 3.3e-17.
                     Score: 54.9. Matches aSDomain:
                     nrpspksdomains_C0216_RS16410_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982137.1"
                     /locus_tag="C0216_RS16410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16385"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_114056005.1"
                     /sec_met_domain="adh_short (E-value: 5e-31, bitscore:
                     106.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREIRSGGRHGTGSPLRGRVAVVTGAARGIGAALARNLSESGMHV
                     ALLGREEASLRATAATLPHRSICFEADVTDDAALRAAARYVEERLGPAGVVAANAGIAV
                     GGPFADTAADLWQRVIDVNLTGSANTARAFLPHLTRTRGYFLQVASTAALGSAPMMSAY
                     CASKAGVESFAQALRGEVEPDGVAVGIAYVHWTGTDMISGIDDHPVLRALRRHQPGFAR
                     RVRTPEQVAAWLAEGIARRSPSVYAPPWLRWCQPLRPLFPAVVARIARRELRTRTRAEL
                     AADVGVLGDGGLADWHAHRHPGHRDG"
     aSDomain        43686..44207
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16410_PKS_KR.1"
                     /evalue="3.30E-17"
                     /label="C0216_RS16410_PKS_KR.1"
                     /locus_tag="C0216_RS16410"
                     /protein_end="193"
                     /protein_start="19"
                     /score="54.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAVVTGAARGIGAALARNLSESGMHVALLGREEASLRATAATLPH
                     RSICFEADVTDDAALRAAARYVEERLGPAGVVAANAGIAVGGPFADTAADLWQRVIDVN
                     LTGSANTARAFLPHLTRTRGYFLQVASTAALGSAPMMSAYCASKAGVESFAQALRGEVE
                     PDGVAVGIAYV"
     CDS_motif       43692..43778
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C0216_RS16410_0001"
                     /evalue="3.40E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="C0216_RS16410"
                     /protein_end="50"
                     /protein_start="21"
                     /score="16.5"
                     /tool="antismash"
                     /translation="VVTGAARGIGAALARNLSESGMHVALLGR"
     gene            complement(44593..45645)
                     /locus_tag="C0216_RS16415"
                     /old_locus_tag="C0216_16390"
     CDS             complement(44593..45645)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380449.1"
                     /locus_tag="C0216_RS16415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16390"
                     /product="aldo/keto reductase"
                     /protein_id="WP_114056006.1"
                     /transl_table=11
                     /translation="MRYRVLGKTGIEVSTHCLGTMMFGGVGNPDHEDAARIIHTALDAG
                     VNFVDTADMYSAGESEEIVGKALKGRRDDVVLATKVHFPLGEGRNRSGNSRRWILKAVE
                     DSLRRLDTDWIDLYQVHRPDHTTDIEETLSVLGDLVTAGRIRAFGCSAFPAEDLVEAHH
                     VAERRGLMRMRTEQPPYSILARGVERAVLPTAQRLGMGVLTWSPLASGFLSGAVRQGRP
                     VDLTTGRAARTPHRFDPALPGNAAKFEAVEELVALAGEIGCTLPELAVAFPLVHPAVTS
                     VIIGPRTMDQLTSLLKGADLLLDDAALDRIDAIVAPGTDLYRADGVWQPPSLTDTAARR
                     RPPADRPAAA"
     gene            45884..46462
                     /locus_tag="C0216_RS16420"
                     /old_locus_tag="C0216_16395"
     CDS             45884..46462
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104881.1"
                     /locus_tag="C0216_RS16420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16395"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_246042576.1"
                     /transl_table=11
                     /translation="MSDHHPGAMPSPDRPRAGTAWCGLLGRRVAEAVAADVMSAASVFD
                     GADALPESADRGFAVPLAAEVWVFDDSLSRVLLVRHPWRGWVAPGGRVEPGETPREAAR
                     RELFEETGVRARLLAEPAAATVRSYRAGAPACLGLSYAAVVDGAVPLVAEDGQAVAWTS
                     LRRGWTGWFPEDVARVRRYAGRLRGGAGD"
     gene            46611..46826
                     /locus_tag="C0216_RS16425"
                     /old_locus_tag="C0216_16400"
     CDS             46611..46826
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849628.1"
                     /locus_tag="C0216_RS16425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16400"
                     /product="hypothetical protein"
                     /protein_id="WP_114056008.1"
                     /transl_table=11
                     /translation="MRGIGGCIALILVGAILTFASDWKMEGVNLDVVGLLMMGTGILGL
                     AVYASVLRRRRVSAVVPVVEETRERP"
     gene            complement(46847..47743)
                     /locus_tag="C0216_RS16430"
                     /old_locus_tag="C0216_16405"
     CDS             complement(46847..47743)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988735.1"
                     /locus_tag="C0216_RS16430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16405"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_114056009.1"
                     /transl_table=11
                     /translation="MSTTTGPAWTVGDDITVHRIDETPLPPATGPWLLPAATPEVVAGE
                     DWLRPHFADGAGVLHLDSHSFAFTAGGLRVLVDTGIGNGKQRANPAWHDLDTGYLERLT
                     AAGYPPEAVDLVLLTHLHADHVGWNTRKQNGRWIPTFPHARYVASRTEREFWAGHAMDE
                     ARRRMFLDSVVPVEEAGLLDLVDVPAGGVGITPQVRLLPTPGHTPGHTAVEVAGRGGTA
                     VITGDCIHHPVQVARPGIGSCADIDPELAEATRRELLASLAGTDTLLLGTHFAPPTAGR
                     VVRRGDSYRLTPVPAGR"
     misc_feature    47739..47754
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 16.59"
                     /tool="antismash"
     misc_feature    47823..47835
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.22"
                     /tool="antismash"
     misc_feature    47849..47864
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.36"
                     /tool="antismash"
     misc_feature    47856..47871
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.46"
                     /tool="antismash"
     gene            47891..48106
                     /locus_tag="C0216_RS16435"
                     /old_locus_tag="C0216_16410"
     CDS             47891..48106
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192000.1"
                     /locus_tag="C0216_RS16435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16410"
                     /product="hypothetical protein"
                     /protein_id="WP_114056010.1"
                     /transl_table=11
                     /translation="MPDTDPEPTAAQAALWAARAGLPLPPGRRAAAAAAARHIHSVVVV
                     LRELDFADTPPAFAYRAHQEAPDAAV"
     gene            48093..49487
                     /locus_tag="C0216_RS16440"
                     /old_locus_tag="C0216_16415"
     CDS             48093..49487
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669781.1"
                     /locus_tag="C0216_RS16440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16415"
                     /product="amidase"
                     /protein_id="WP_114056011.1"
                     /transl_table=11
                     /translation="MQPCELSLAEAAEAIRTRRLSPVELTDSVLRRLELTEPRLNAYAA
                     VTAERARADARTAAREIAAGRRRGPLHGIPMGLKDLIDVAGVPTSAGSRVRTGHRARAD
                     STVAARLAAAGAVLLGKTHTHEFAYGLTTPQTRNAVDPGRIAGGSSGGSAVAVAAGSAT
                     FAVGTDTGGSIRVPAALNGVVGLKPTHGLVPRHGVTSLSWSLDHVGPITRTVRDAGLVL
                     DALAGHDPRDPASIAAPLAADRRPPAGTGLAGLRIGVPRTYYFDRVDADVEAAVRRAID
                     GLRGLGARLVGVDIPMARHIQAVQWSLMVPEATAYHERTLRTVPELYQDDVRVLLEAGA
                     LMPAGDYLRAQRARTLMRREWSRLLRGVHLVAAPAVPTTAVRAGQECVTWSDGTTEAVS
                     DAYVRLSSPANITGFPALTVPVGRDASGLPVGMQLLGRPLGEEVLLRVGHAYEQAREAD
                     RPAHAA"
     gene            49562..50113
                     /locus_tag="C0216_RS16445"
                     /old_locus_tag="C0216_16420"
     CDS             49562..50113
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1224: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019982437.1"
                     /locus_tag="C0216_RS16445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16420"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_114056012.1"
                     /transl_table=11
                     /translation="MVRPGGRSARVQASVHAAVRELTAEVGRDALTVPLIAQRAGVTPS
                     TVYRRWGDLQELLSDVAVERLRPDTAPADHGTLAADLTAWAEQFLDEMSSPAGRAYVRD
                     ALLGDPDGGNAGQCSAYAAGHIGVILERAAARGERAPDTEAVIDRVVAPLVYRILFRPD
                     GLDTARARALVVSLLAPAPR"
     gene            complement(50356..51147)
                     /locus_tag="C0216_RS16450"
                     /old_locus_tag="C0216_16425"
     CDS             complement(50356..51147)
                     /NRPS_PKS="Domain: PKS_KR (6-165). E-value: 1.4e-11. Score:
                     36.5. Matches aSDomain:
                     nrpspksdomains_C0216_RS16450_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944413.1"
                     /locus_tag="C0216_RS16450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16425"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_114056013.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.1e-05, bitscore:
                     23.1, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFDGSTVLLTGATGGLGTELAGALAGRGASLVLTGRRKDALQAV
                     ADRFAARAVVADLADPADVERLAEECGDVDVLVANAALPSSGDVLDYTPAQVERALAVN
                     LHAPVLLARLLAPRMVRARRGHIAFVGSISGKAATRSSALYSATKFGLRGFALAFRQDL
                     HGTGVGVSLVQPGFVRDAGMFAATGAKPPAGMRTVSPAQVCDGLVRAVERNLCEVNVAP
                     AELKLLSAIAGQFPAFAERVQGRMGVERTLNDIVTAQRDAR"
     aSDomain        complement(50653..51129)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C0216_RS16450_PKS_KR.1"
                     /evalue="1.40E-11"
                     /label="C0216_RS16450_PKS_KR.1"
                     /locus_tag="C0216_RS16450"
                     /protein_end="165"
                     /protein_start="6"
                     /score="36.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TVLLTGATGGLGTELAGALAGRGASLVLTGRRKDALQAVADRFAA
                     RAVVADLADPADVERLAEECGDVDVLVANAALPSSGDVLDYTPAQVERALAVNLHAPVL
                     LARLLAPRMVRARRGHIAFVGSISGKAATRSSALYSATKFGLRGFALAFRQDLHG"
     CDS_motif       complement(50755..50817)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C0216_RS16450_0002"
                     /evalue="3.10E-01"
                     /label="PKSI-KR_m1"
                     /locus_tag="C0216_RS16450"
                     /protein_end="131"
                     /protein_start="110"
                     /score="3.8"
                     /tool="antismash"
                     /translation="LARLLAPRMVRARRGHIAFVG"
     CDS_motif       complement(51034..51129)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C0216_RS16450_0001"
                     /evalue="6.70E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="C0216_RS16450"
                     /protein_end="38"
                     /protein_start="6"
                     /score="22.0"
                     /tool="antismash"
                     /translation="TVLLTGATGGLGTELAGALAGRGASLVLTGRR"
     misc_feature    51119..51133
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
ORIGIN
        1 gcgccggccc gccggccgtc cgctgtcctc cactccccca gtgtggcgcc gcggcggcac
       61 cccggtcggc gggggcggcc cttcggggca cgccccgggc ggccgccgcg cggcggtccg
      121 gcaggtcggc cgggtacggg atatcagtgg ggcaggcggc ggtcaccgcg gccgccggtg
      181 agaggaaggc ggggagcctg tggccgtcaa acccgttccc gagggatatc cgcgcatcac
      241 cccgtacctg tgctgcgacg gagcagcgga ggcgatcgac ttctacgtgt ccgtgctggg
      301 cgcgaccgag cggacgcgca tgcccgcccc cggcggcagg atcggacacg ccgaactgga
      361 gctgggcaat tcggtcgtca tgctggcgga cgagcacccg gacatgggct tccgctcacc
      421 gaagtccgtc ggcgggacgc ccgtcaccct gcacgtgtac gtcgaggacg tcgacgcggt
      481 cttcgccgcc gccgtcgccc gcggcgccag ggagcttcgt ccggtccgcg acgagttcta
      541 cggcgaccgc accggccaga tcgaggaccc gtacgggcac cgctggagcc tcgcctcgca
      601 cgtggaggac gtgtccgagg aggagatgga gcggcgggcg cgggaggccg tgcagggcgg
      661 cggctgacgg cggggcggca gcagggcggg gtgggtgcgg ggccgggtcg gggccgcggg
      721 ggccggggcc gggtaattcg gcgggggcgg ggtgccggcc gggtgatact ggggcgcggc
      781 tggtcggaca tcatccgccc accagtcccc cacccggcgg cgttccgccc ggctgttggt
      841 cttttccacc ctttcgagga gcaccacgag catgtcgata cccccgcagc cgccgccggg
      901 cccgtaccag cagccgtatc ccccgcaggg cccgtacggc ctgccagggc agcccggaat
      961 gcccggagta cccgggcagg gggccccgtt cggcggcccg cagggctggt acccgccgca
     1021 gccgcagaag acgaacgtgg cggccatcgt ggcgctcgtg atgtcggtgg tctgtgccat
     1081 cccgttcgtt cctctgatcc tgggcttcgt cgccctctcg cagatccgga agaacggcga
     1141 gaagggcaag ggactcgcga tcgcggcgat cgtcatccac ggggcgacga tcgcgttcta
     1201 cgcgatcgtg ctcgccatcg gactgctcgg cggggcggcc gacgacgccg cggcgcggca
     1261 ggacgccggc gggcgggtca ccgtgccgga gcagagtgcg agccccggcg cgaacgccgg
     1321 cgcgagccct ggtgcgagcc cgcgcgagcg ccgcagggac gtcgaggaca tccgcaaggg
     1381 cgactgcttc aacaccgagg acgacctggc gaagaccgag gaggggggca ccgaggcccg
     1441 ccagtcggtg cggaccgtgg cgtgcgacca gccgcacgag ggcgaggtgt acgccgtgct
     1501 caccctggag ggcggggcgt tcccgggcgc ggacaaggtc gtcgcgagcg ccgacgagaa
     1561 gtgcggcggc aaggcgctga cggactacgt gggcagtgac gcggcgaagc tgccgaagtc
     1621 gcttgaggtg ttctactact acccgcaggc gtcgagctgg gtcctgggcg accggacggt
     1681 cacctgcttc ctcggcagcc cggccgggac gaccacgggc tcggtgcgcg cgaacgcctc
     1741 ctgagacccg ccccgcaccc gcaaacggcc ggccgcccac accgcggccg gccgtttgcg
     1801 tgcgcggggc ggcgggcggc ctgcggcggc cggtcagcgg tagtcgagtt cggccagttc
     1861 acgggcgagg cggttccgga aggccgggat ccgggcgagg acgggcagca gcgtgttgcg
     1921 cagggcgcgg cgcgtcaggc cgcgggcggt ggcgacgcgg gtcatccggt cggtgagggc
     1981 gacgacgcgc tgggcgacgg ggcggcgcct ggcctcgtac gcgtcgaggt cgccgtccgc
     2041 cagggcgcgg ccgagggcgt agccgtcctg gatgccggtg ttcatgccct gcccgccggc
     2101 cgggctgtgc acgtgcgcgg cgtccccggc gagcaggagg cgcccggcgc ggtagcggtc
     2161 ggccacgcgg tggtggatcc ggaaccggga ggaccacacg aggtcgtgca cgcgggcctc
     2221 gccgcggagc cgctgcgcca gcagggcccg cacgaaggcg aggtccggag acggcggggc
     2281 ctcggcgacc gtggcgacga tccggtagcg ccggccggcg ccgccgcccc cgcccacgcc
     2341 cccgttcccg tttcccggca gcggggcgat gacggtcagc ccggcggcgc cgaaggcgag
     2401 cgagacctcg ctcgggccgg gggcccagtc catgacgacg tcggcgagga cgaaggactc
     2461 gtcgtacgcg ctgcccgtga agccgatgcc cgctgccgcg cggacggtgc tgtgcatccc
     2521 gtcggcgccg acggcgtagg cggcgtgcag ggtctcgccg gcggcggtgg tgagggtgac
     2581 gccgtcggcg tcctgggtga cggaggtgac ctcgcggggg cggtggacgt cgcccccgag
     2641 tgcgcgcagg cggctcagca ggacggcctc ggtctcgtac tgggggacca tcagggcgta
     2701 cgggtgggcg gtcggcaggc cgtcgaagtc gacggccgcg aggggacggg cgccgtcgcg
     2761 gatccggaag cgggagacgg ggatgccgcg ggccacgagg ccggcggaga gcgcgccgct
     2821 cgggtcgagc tcgtcgaaca cctccagcgt gcgggcgtgc acgacggcgg cgcgggaggt
     2881 gttggcgccc tcggcctgcc ggtcgaggag gacgaagtcg acgccggcct cggcaagggt
     2941 cacggcgagg gcgagcccgg tgggcccggc gccgacgatg gccacctccg tgcgggaggg
     3001 cagtacgggg gtgctggtca ttgcggacct cctccggcgg gccaacactt gttggccaac
     3061 gtctgttgac ttgaggatgc cctcgcgcga ttcgcctgtc aacagttgtt ggcctacgct
     3121 tgttggcatg acgacgccgc gccgctccga ccagaccaag accgccatcc tgagggctgc
     3181 gcgggaacgc ttcgccgccc acggatacga gcgcacgacg atccgcgccg tcgccgcgga
     3241 cgcggagatc gacccgtcga tggtcatgcg gtacttcggc agcaaggagc agctcttcga
     3301 cgccgccctc gcggtcgacc tgcgcctgcc cgacctgggc gcggtgccgg ccgagcaact
     3361 gccggccacg ctggtgcggc acttcgtgga ccggtgggag ggcgacccgg cggacgacgc
     3421 cctgctggtg ctgctgcgct ccgcggtgac gaacgagcag gccgcggccc gcatgcgcga
     3481 ggtgttcgcc acccaggtgg cacccgcact ggcggcagcc ctcggcccgg accgggccgc
     3541 ccgcacggcg ggtctggtcg ccgcccagct cctcggcctc gccctgaccc gctacctcct
     3601 ggcactcccc ccggtcgtcg ccctgccccc ggacgacctg gtcaagcgcc tggccccggc
     3661 cctggccgcc accctggccg gctactaggg gctgtattga gttgccccgt ggagcaagga
     3721 gcggcgttcg gtgcgtgccc tcggcgcgcg ggacggcccg gcgcacggcg gcgggttggc
     3781 gccctggatg gtgggcgggc cggcgccggc tcctggggcg agcagcgtgg ttcctgcgcc
     3841 gcgaagagtg accagagccg tgcaggcggg gtcgagcgcg tcgaccgggc gcccgtagaa
     3901 gaggatgcgc gtgagcacca ggtcgatcgg cgccgcggcg tcacggagtc ggtggaagcg
     3961 tgcgccgagg cggaccggcc cgtgcgtgca gcgcacggct gcggtcgccc gggtctcgtc
     4021 cacggcccgc aggtggtcga tccggaactc cgcgtcgacc gccgtccggc ggtccgggtc
     4081 gggggtcgcc gtcatcccgc cgtgatctca gggcgttcga cgggcccggc ccggtcaggg
     4141 cgtgggggcg ggccgcggcc gaggcacggt tccgtgttcc cggggccgca gccgcccccg
     4201 ggcggggcgg atcgcggcgg gcgtgcgtag cctggcggca tgcgtatgcg tcccaccctg
     4261 agctggaccc cctccgggga tctgccgccc ggcacgacgg agctggggcc cgtcgtcgat
     4321 gtgcttgccg ccggcagggt gctcgtcctg agcggcgcgg gcctgtccac ggagtcgggc
     4381 atccccgact accgcggcga gggcggcagc ctcagccggc acaccccgat gacgtaccag
     4441 gacttcgtct cgggcagcgg ggcgcggcgc cgctactggg cgcgcagcca cctcggctgg
     4501 cgtacgttcg gccgggcgcg gccgaacgcc gggcaccggg cggtggcagc gttcgggcgg
     4561 cacgggatgc tcgcgggcgt gatcacccag aacgtcgacg gcctgcacca ggccgccggc
     4621 agtgacgggg tggtggagct gcacggcggc ctcgaccggg tcgtctgcct gtcctgccgc
     4681 gcctccaccc cgcggcgcga gctggccctg cggctggagg aggccaatcc ggggttcgag
     4741 ccggtggccg ccgcgatgaa cccggacggt gacgccgacc tcaccgacgg gcaggtcgcg
     4801 gacttccgcg tcgtgccctg cgcgcggtgc gggggcgtcc tcaagccgga cgtggtgttc
     4861 ttcggcgaag ccgttccgcc gtcgcgggtg gagcagtgcc gggcgctcgt cgacggggcg
     4921 gacgcggtgc tggtcctcgg ctcctcgctc acggtgatgt cggggctgcg gttcgtccgc
     4981 caggcggccg gggccggcaa gccggtgctg atcgtgaacc gggacgccac ccgcggcgac
     5041 ccgcatgccg tcacgcgggt cgcgctcccc ctcggcgcgg ccctgaccgc ggtggcgggc
     5101 cgcctgggcg tcgccgtcga cggcgaggag gccgggtagc gcccggcggt ggccggttca
     5161 gccgccctgg tccttgcggg ggcgcgcccc ctcctgcggg tccgtctgcg cgtcctggcc
     5221 ggggtcgggc tcgtgtcctg cccgtgcccg ttcgcgctcc tgttcctgct tgcgctgccg
     5281 gttgagctcg tccttgcggg ccttgccctg cgggtcggtc atcgctcggc tcccttcctc
     5341 cgttgcctcc gggccgctgc acgcgtacgc gccgcgtacg ctcctgcccg gcgtgtcccc
     5401 ggaaacgggc cgcggacacc cgcgggccgc ctccggagag ggccgccggc ctccgggccc
     5461 ggcatggccg tgtccccgtg cgggcgggag gcgcccggca cgaagccggg gccgcggccg
     5521 ccgcggtgcg ggcagcgggc atggtgccgc cggaggcacg ccggggtgcg cgggtcagga
     5581 ccggcagcgg agcatctcca gcggcgggtg cgcgaggagg tcggcccaga agtcggcccc
     5641 gtactcggcg atgccctcct cggacacgtg cagcggcacc cactccaggt cgcggaatcc
     5701 cgcccgccgc aggcactcct cgtagacctc gcggcgcggg accgtgccga ggatgctgat
     5761 cggctccggg tcgaggagcg cggtgacccg gacgagcggc ccggcctccc gctcctcgcc
     5821 cgtcggctcg cagcggaagc cgtacgtgtc caggctccgg cagtcgaagc ggtagtcggg
     5881 cttctgcgcg aacacgaaga acgcgccgcc cggcaccagg ttgcggtgga tgttgcggca
     5941 catgcgctcc atctccgctg tgtcggaggc gtagttgagg cactgcaccg ccagggcgat
     6001 gtcgaactgc cggtccagct gtcccagtcc ggcggcgtcg ccgacctcgt agcgcacgcc
     6061 cagcggctcc tgttcctcga tccgccgcgc ggcggcgatc atctcggcgg agatgtccac
     6121 gccgaacacg tccgcggcgc cgcggcgctt gaactcccgg ctgtagaagc cggttccgca
     6181 cgccacgtcg aggaccgagc ggcctttgac gtcaccgacc atgccgagga agctcggcac
     6241 ttccccgtgg cggatcagcg gcagggactt gaagccctcg aaggcctcgc cgatgccgtc
     6301 gtactgctgc tgcacgctca cgtgcgcccc ctctgtgccg tgcttcgtcc cggatgcagg
     6361 ccgcaccggg cccccggcgg agtgcggagg agggcccggt gcggcgttga cagaagtctg
     6421 ctgccggcaa gtccgggagc cgtactggca gatggcacga atcagcgggc ggccggtccc
     6481 cgtatcggcc aaccacctcg gactgctgtg tgctccgttg tgaggagagc ccttcgtgcc
     6541 ggtgaaccgg gcgcggctca gggggtgggc ggcggcgtcc agagggggtt gcgtccgctc
     6601 aggccgaccg cccggtcgag cagcggcgcg tcgtcgggca cgggcacgac gggcccgaag
     6661 atcccgcccc tgccggcatc gtcctcctcg gcggacgcgc ggaggaaggc gtacgaggcg
     6721 tgcagcgcgg ccggatccgg gtcgtacggc aggccggcgg cccgggccag gtcccagccg
     6781 tggatcacca gctcgtcggt ggcgacggcc cccgcgaccc cgccggggag ctccacgccc
     6841 ccggcgcggg tcatgccggt ccaggcggcc gggtcgcgcc aggcgaccgc catctcggcc
     6901 agcagccggg gcagctgctc ccgccattcc gcgggcaggc cgggtacgga gccggcgtcg
     6961 ggagcggtgg cggtcgtcgg gccgaggtcc ttccgggcgg cgtcgcggaa ggcggtcgcg
     7021 aggcccgcga ggtgggcgag caggccgccg acccggtatc cggggcaggg tgtggggtcg
     7081 gcgagccggt cgtccgggac gtccgccgcg agccgcgcca cgatccgggc ctgtgggcgg
     7141 aggtcgatga acgccgcgtc ggtcatgtgc cgctccttcg gggatggtgg atcgaagggt
     7201 aggccggcgg tgtacccggc actcaccgca acacggacct cacccgcccc accatcgccg
     7261 atccgcccgg acgcgcgccc ggacgccggg aaaccgcggt gccgggcggc gccgaacttc
     7321 gacgagaccg tgcccggtga gcggaggatg ttccggcgtc gccgtctcgg cccgttgtca
     7381 gtggggaccg gcaggctggt gggatgacac cgttgcttct tgccgacatc gagcgggccg
     7441 tccgcgacag ttggagtgcc gacacctgca cccccgacta ccggtcgctg tggaccggcg
     7501 acaacccggc ccgcgaccag tgcggggtga ccgccctcgt cctcaacgac ctgctgggcg
     7561 gcgagctggt ccgcggcgag gtccacgtcg acggcaggcg cgtcgactac cactggtgga
     7621 accgcctcgg cgccggcgtc gagatcgacc tgacgcgcga gcagttcggc ccggaggaga
     7681 cggtcgtggg cggcaccgtc ataccccggc cgccgcgcgc gcagccgcac cggctccggg
     7741 aggagtacga actcctccgc acccgggtcc tggaacgcct ggcgcagccg ccgggggaac
     7801 ggaccgggcc ggcctcggcc acgccgcccg ccggctgacc ggccggacca ccaccgggcc
     7861 cgccgttcac ggcgccccgc cgaggcttcc ggccggccgg gccccgccgt gccccgggct
     7921 ccggggcgcc cgttcggcgc cggccgcctg gcggctgccg ccgaacggag gtcaggcccc
     7981 ggccgcgtcc aggaggaggc gggccagttc ctgcggttgc gagaacatcg gccagtggcc
     8041 ggtggccatg tcgatccgcc gccagcgcgg cccggtcagc agccgggcca cgtcgtcggt
     8101 cggctcggcg ccgtcgagga ggcacttgac gtacgtcgcc ggcagctcct ccagcggccg
     8161 gaccagcacg gcggggtcgg ccagggatgc gcccgggtgc ggggtcgcac cggccgtgaa
     8221 ccgggcgatc tgccggtccc cgagcccctg gcccgcgcag tcggccgcgg tgaccggcgc
     8281 ccagaggccg ccgttcgcgg cgatggcgtc ctcgagcttc gccgggccct cccaccaggt
     8341 ggagacgaag gactccccct cggccgggac gttggagtcg aggaagacga cccgggtcag
     8401 ccggtcactg atccgcccgc cggcctggcc gaccgggatg cccgagtagc tgtgcccgac
     8461 cagcacgacg tcgtgcagat cgaggcgctc gacctcgtcg acgatgtcgc ggacatgggt
     8521 ctgccgcccg acgggcacgt gccgcttctc ggccaggccg gacagcgtca gcgggtgcac
     8581 gccgtggccg gcccggcgca gtgcgggcac cacctcgtcc cacgcccacc ctccgagcca
     8641 tgcgcctgcc accagcacga agttcgccat ggggggcagg gtagcgggcg ggtccgacaa
     8701 ggcaggcgcg ctactcgcat tcggacatcg gcgggcgccg gcgccggcgg ggcgcggtga
     8761 tgagtacggg tactcaggcc gcggcggatc ccgtacggca gggtgttccc atgcaccagc
     8821 gtgaatggaa gcccgcggac caccgactcg gcatcgaacg cgccggcatc gccgtcctgg
     8881 cggtggcggc ggccctcgcc gctgcggcgg ccatcgccgt gctgtccgtc gtcaccgtcc
     8941 acgccctcgc ctgacgggcc gaacgcgccc ccgcgggtgc cggaccggtc ggccgctcgt
     9001 tggacccgca ggagggaccg gacgcggacc ggtccgtccg ccgccctgcc gtccgtacgt
     9061 ccgacacctg ccgaggagcc cctggtgaac ccctccgatc agccgcgcgc ggtcgccgcg
     9121 ctcctgcccg ccgcaccgtt gcaggaccac cccggcggcg actcccgcgg tgtcctgaac
     9181 gtcgtcggcg tgcacctcta cctggagcgg gacggccgcg tcctgctcgg gctgcgccat
     9241 cccgactcgg cgttcgcggc gcgtacgcac cacttcctcg ccggccactg cgagcgggag
     9301 tccgccgtcg cctgcctggt gcgcgaggcg gaggaggagg ccgggctggg gatcgacccc
     9361 gcctacgtgg aactcgtcca cctggtgcac gtcgtgcacg gtcccggcga ccggccccgc
     9421 atgcagctcg tcttccgcgc ccgcgcctgg acgggcacgc cggaggtgcg ggagcccgac
     9481 cggtgccttt cctgggactg gtggcccgcc gacgccctgc cggaccgggt cgtcccgtac
     9541 acccgcgccg cgatcgaggg catccgggcc ggccgcctgt acaccgaact cggctggtga
     9601 ccgcgcgccc ggacgccgca gccggccgtt gcggcggaag gcccggtaca gcgatgtcct
     9661 cggcggcgtt gggtgcagtc cgcggagaac acgccgtcct ccaaggcggg tcagggccgc
     9721 gcgggccgtg ccggcggggt ccccgcaggc gccgacgacg acctcgagga cggtatgggc
     9781 ggcggcgagc gggccgtggc agagcagcac cgggtcgttg ccggtgacag cccttcagga
     9841 aacgccggag gtagagggtt tggcggcgcc ggggcgggtc acacgcgtcg acggcggggt
     9901 ctgcggtcgg acttcggcgg accccgccgg gcctgggccg tgcacgtgct caccggcggc
     9961 ccaggaccct tcggcatcac gggcaccaag ggccacaagg gcaccgaggg gagcacccgg
    10021 ctgccgaacg ggatccgcac ggcatacggg ctgcgccccg cccgccctcc tccccgggcg
    10081 ggtgcgggcc gtgtcccggc aggcccccgg ccacggcgct cggaccgccg tccccgggct
    10141 cgcggaatcc gtacggctgc cgcccgcccc cgacgaccgg ccgggcccga ggagcccctt
    10201 gcccggaagg attcctcatg gggatacgca ggaagttcgc cggttcgcgg ccgtgggcgg
    10261 gcccgccgcc gcggacggcg ccggggcgcc gtccggtggt gcgggcgctg gccgtggcgg
    10321 ccgcgttcgc cggcacggtg ctgttcagcc tggccctggc acgggtgacg ctggagccgt
    10381 cggccgcctc ggcggggctc gtgcacagca acgtccaccc gggcgcctcg atccggcagt
    10441 acctggagca gggctccgcc ggggacgccg cgcggcagct cggcggaaac ctgctgctcg
    10501 gcgtgccgtt cggcctgctg ctgccggtga tggtgccgca gacacgcggc ctgctgcggg
    10561 tcgccgcggt gacggccgtc gtgatgaccc tggtggagct ggtccagggc gccctcgtca
    10621 cggggcgcgc cttcgacgtc gacgacgtgc tcctcaacac cgcgggggct ctgctcgggt
    10681 tcctccttgc gggccgccgg atgagccggg cggtgcaccc gcgccgccgg cgctggtggc
    10741 accgcctgcc cgggttcggg ccgcgcggcg gcgccagagc ccccgaggcg ggcggcggcg
    10801 gggccgggcc gccggcgtga ccgcgccggg ccgccgggcg acggggtgcg taggggcgcg
    10861 cggacggggc aagcggcccc tgtccgcccc cggagggcac gcctccggca cgcggaggcg
    10921 tgcgtggcga gcgacgagga ggcaccatgc cgaaccggcc tgcgggcgac catctggaag
    10981 ggctgcgcgc gcgggtcgcg gcgggcgggg agcacgggct caccccggcg gagcacgagg
    11041 agctgcagcg gctcctggac agggccgggc gggacggggc gcgggacgac ccgggcctgg
    11101 ccgagtcgct ggaggaggcc gccctgcgtt tcgaggcccg tcatccgtcc gtctccgccg
    11161 ccctgcggac ggtcggcgtg aacctggcca acctcggcat ctgaccgccg gcggccggcg
    11221 taccgcgcgg tctcccgccc cggccccatc ccctcgcgaa gggaagacac ccatggctcg
    11281 accgaggatc ctcgtggtcg gtgccggctt cgccggcgtc gagtgcgtgc gccggctgga
    11341 gcgccggctc atgcccgggg aggcggacat cacggtcgtc accccgaact cctaccagct
    11401 gtacctgccg ctgctgccgc aggtcgcctc cggggtgctg accccgcagt cggtggccgt
    11461 gtcgctgcgg cgcagtgagc gcaaccgcac gcggatcctg ccgggcaccg cggtcggtgt
    11521 ggatccggcg gcgaaggtgt gcgtggtgcg cacgatcagc ggggacctca ccgaccggcc
    11581 gtacgaccac ctcgtcctgg ctcccgggag cgtcacccgg accttcgaca tccccgggct
    11641 tgccgagcac gcgcggggca tgaagaccct cgccgaggcc gcgtacctgc gcgaccacgt
    11701 catcgcacag ctcgatctgg cggacgcgtg cggcgacccc gccgagcagg acggccggct
    11761 gcggttcgtc gtggtgggcg gcgggtatgc cggtacggag acggccgcgt gcctccagcg
    11821 cctgaccacg catgcggtgg agcgctaccc gcgcctggag gcgcgccgga tcagctggca
    11881 cctcgtggat ctggccccgc ggctgatgcc ggagctgggc gacgccctgg ggcgtgccgc
    11941 gctggacgtg ctgcgccggc gcggcatcga ggtctccctc ggggtgagcg tcgccaaggc
    12001 cggtgccgcg gaggtgacgc tcaccgacgg gcgcgtcctg cccacccgta cgctgatctg
    12061 gacggccggc gtcgcggcga gcccgctggt ggcgaccctg gggacgccca cggagcgggg
    12121 acggctcgcc gtcacccccg acatggccgt gccgggtgcg ccgggggtgt tcgcgctggg
    12181 cgacgccgcc gcggtgcccg acctcgtgca gggcaccgag ggggccgtct gcccgcccac
    12241 cgcgcagcac gcctcgcggc aggggcgtac ggtcgccgac aatgtgatcg ccgccctgcg
    12301 cgggcagccg ctgcgcccgt accggcaccg cgacctgggg ctcgtcgtgg acctcggcgg
    12361 tacggacgcc gtgtcgaagc cgctgggggt gccgctgcgc ggtctgccgg cgcaggcggt
    12421 ggcgcgcggc taccactggg gggcgctgcg gactggcgtc gcgaagaccc gcgtcctgac
    12481 gaactggctg ctgaacgcgg tggccggcga cgacttcgtg cggaccggct tccaggagcg
    12541 gcggccggcc acgctgcggg agttcgagca gaccgacgcc tacctgacgg cggaggagat
    12601 ccgggcccgt acggcgcgct gacggcgcgg accgcgggac ggccgccgtg cgcggccgtc
    12661 ccccgggtgc ctcacggccg gccgaggagc gccgttccgg ccgcggagtc cgtgcgggcc
    12721 gtgaagaagt cggtgaacgc ggcgacgaac tccgcttcgg cgacacggcc gtcgccgtcc
    12781 gcgtcgagct gccggaatcc gtggttgagc tcggccgggt ggatgcgctt ccctccgaac
    12841 agggtgcggt actcgtcggc gcacaggtgc ccgctgccgt cggtgtcagc cgcgcggaac
    12901 agggcgcgca tcgccgggac gaggcccttc tccaggtagt ccgggtcccg gtcgagcccg
    12961 gtcagcatgg cggtgacgaa ctccgcgcag tccacgccgc cgtcgccgtc cgcgtccgtg
    13021 cccgcgcaca ggtggcgcca ccaggattcg aacgcggcgt acagcacgtc ctcctgctcc
    13081 gccgggagtt ccagctgcca gcacacgttg tggaccatgg cctggaggtc tgcggagttg
    13141 acgcgtccgt cgccggtctg gtcgaggacc tggcggaaga aggcctccag gcgggccgga
    13201 cgggagtcgg cggtgcgcgg ccgcggcagg cgcagcgcgg gcaccgcccg gcgcggccgg
    13261 ccctggcggg cggggcgcgc gccggtgccg ccgtcggggt ggtgccggta ccgtacgcgg
    13321 tcgggcagga gggtcgtgat ctgccgcatg ccgcggtgta cggcccagga gagggcggcg
    13381 gcgctgcggg ggcgcggcgt gccgaaccgc tcgtgccagg cgggcggcag gtcggccacg
    13441 gtgagcgcgg tgagcgtccg ggcggcgacg gcgcgcagca gcggccagag gggccggagc
    13501 cgcccgaggc ggcggggtgc gggcgcctcg cggagcatgt cgaagagcag gtagcggacc
    13561 tgttcgccgt attcgaggac ctcgcggacg gtccggtcga cgtaggccgg cacgtcggcg
    13621 gcggtgggcg gcagtgactc cgcggggatg tcgagggccg cgcagacctc cttgaactcg
    13681 gcgtacagcg tgtcgagttc gacggcggtg agggggtcgc cggagagggt gcgcatggcg
    13741 gtcatggcct cgtacagggt caccatgacc caggcgcgga cctccgggtc ctctgcggtg
    13801 tagggccgtc cggcgtcgtc ggtgccgcgg atgcgccggt gggtgcgcgc cagccgggcg
    13861 gtttcgcgct cccggtcctc ggggccggcg aagaacaggc gggtgccgct gtccatcgtg
    13921 tgctggatgc gccgccaggg gtgggcccgg taggtggagt agtgggcggt gccggccgcg
    13981 acggcggggt gtgcggtctg caggacgagc agcctccagg ccaccaggcc gatgcgctgt
    14041 tcgccgagga tgcggcggag caggccggcg ggggcgggca gcgaggtgcg ggtcacgtgt
    14101 tgctcctgtg gcgggagggc cgggcagaca ggaggtacaa cggccgtgtg gcgggcgggt
    14161 cgccgggccg cggcccggat cactcccatg tgcggctctg cgaacggctg cgcgcatggg
    14221 cggggcttca gtcgagggtg aactcccagt aggcggcttc gcggtagccg tcgtccgggg
    14281 gccgtacctc gacggtgacg gtcgtgcccg tgcggtcggc cgtgagccgt acgggcacgg
    14341 tgcgcttgcc gtcctcggcc agcgggggca gcagggccgc ggcggactcg ccgcggttgg
    14401 accaccgcac gccgccggag gtgtggcggt ccagggagcg cccggcgcgt acgacgaggg
    14461 gcgcctcccc gtactcggag acggcggtct cggcggagtc gccgccgatg cgctgctccc
    14521 cgtccgtgtc gttgcggtac gtgacggtga tgaggtgggt gccgtcggct ccccggcggg
    14581 gtgcgccgac ggtgaccttc aggccgtcct cgtaccgtgc ggtgcggccc gcggcgaggg
    14641 ggtcggccac accgccgtcg gcgccggagg tctcctccag ctgcccgtac ccgtcgatgc
    14701 cgcgctccag ctcgtgcagt cccacgagcc cgaggcaggc cagcacggcc gccgcgagca
    14761 gcgccgcccc gcaccccgtg aaccggcccg gcgccgcggc cgcgggagcc gcggaggtcc
    14821 ccggccgcgg gtcgcccgcc ggagtcgggg gctgctcggg ggtcgggggg tgtgccgtca
    14881 tggcgccacc gtaggccggc cggggtgggc ggatcatgag cgcccgtact cagctctcct
    14941 gagtaccgtt ccccggtttc cggcggtacg cgctccctgc cgggggcggc gcgggcgtcc
    15001 cgccggggtt caccggctcc tgcgccgacc cgggcagacc ggagcggcgc cgttcccggg
    15061 cggtgtgggc cgctgctgcc agactggcgg ctggcccggc gcgggccctg cccctgcccc
    15121 cgccccagtc gcaccgatgg ggtgcggcgg ccggaacggt ctgccgcaca ccgccggcaa
    15181 cccgaggagg acgtgcacat ggcccagttg ctgagggtcc agaacttcaa cgtgtcgagc
    15241 gacgggatcg gggccgggga ggaccagacc ctggagcgcc ccttcgggcg cgtcgacccg
    15301 gggaggatgt tcgcgtgggc cggtgccacg gcgagctggc cgaaccgcac cgagccgggc
    15361 ggcagccggg gcctggacga ctacttcacg cgggacttca cccacaacat cggcgccgag
    15421 atcatgggcc ggaacaagtt cgggcctcag cgcggcccct ggcaggacca cgcgtggcgc
    15481 ggctggtggg gcgacgagcc gccgttccgc acgccggtgt tcgtgctgac ccaccacccg
    15541 cggccctcgt tcaccctctc cgacaccacc ttccacttcg tgtccggcga gccggcggcc
    15601 gtcctcgacc tggcgcggga ggccgcccgg ggcaaggacg tgcggctcgg cggcggagtg
    15661 cgcacgatcc gcgagttcct ggacgccgac ctcgtcgaca ccctccacgt ggcggtctcg
    15721 ccggtggaac tcgggtcggg gctgaagctg tgggactccc cgcaggacct cctcgaccgc
    15781 ttccacctgg agaccgtccc gagcccgagc ggggtggtgc accacctgtt ctggcgccgg
    15841 tgacgcgcgg ggccgcggcc ccgcggtgtg ccgggggcgg cgctcacggc ggcgggggca
    15901 ggagtctggg gaggaggtcc tccggggcgg cgtccaggtg gagctggagc aggcggtggg
    15961 ggaagaagta gccgctgtcg gtgcggtgga ggaggacgcg ctgctccgcc gcgtcgagga
    16021 agcgccggta gcggtacggg gtgcggccgc gctgcgcgag caccgcgcgg accgtccagt
    16081 ggtgtacgac ggccagcccg ccgaaccgga agccgcggat caccgcgaac tgcccgccca
    16141 gcagggccgc ggcgaacgcg gccctccgca gcgagtcgcc gccgggcgcg gccgccgtga
    16201 tcagggcgag caggccgagg ccggctgcgg ccaggcccgc gaggccgtgg accaggcaga
    16261 agcggaccga gcggcggacg ccttcgttcg ggcgggggcg gcggtcctgc agcgacggct
    16321 cgaactggtt tccgaaggcg tacaggaagc cgaggaacac cgcggcggcc ggcgcgatcc
    16381 acgcgggctg cgggcacagc agcaggacga cgtatccgag caggcagatg agcgccaccg
    16441 agacgaggcc ggacagcagt ccgcgcgcga ggtggtactt cagcggcgac gagtagatca
    16501 tcagctcctg ccggaaccac gtccaccgca tctgctcgac gggctggaac acgggcgtga
    16561 acgaggcttc gagctgggtg agggccaccc atgcgtaggc gagccccacg atccagcacc
    16621 ctggcgccgt caggtcggcc tccaccacga agaccagcca gcacaggatg aggaccatgg
    16681 cgggcgcgtt cgccgccatc ggcgcggcga ccgcgccgcg ctgctccaca cgggggccgc
    16741 cgcccctggc gaggtggtgc ttctccgact ggtacgcctg cgccgcgacg ttcaccgcca
    16801 tcgccgcggc gagggccgcg gcgtcccgca cgctcgtgtc cagcatcccg gccgggacgg
    16861 ccgccgccag ccacaccacg ggcaggccga gggccgccac cgccatcacg acgttgggga
    16921 cgatccgcgg cagcacctgc tccgcgggcg tcagccaggt caggtccagg cggtccaggt
    16981 acagcacgtg ctccttgcgt gcggtgagca tccgcgcgag ggaggccagc cacgtgaggg
    17041 tgcgctccgg gtccgcgtcc gggcgggggc gctcccggcg caggcactcg cgggtgtagg
    17101 cgtcgaggat gcggccgcgg cgctcggcga ggctgcccgg cgcacgcagg tcgtccgccg
    17161 gccggtagcg gtaggtgagg cggatgaagt tcagcatcat cggcgactgg aacagcggcc
    17221 acaggtccgg atcgccctcc agcgcggcgt gcacgtcggc gagggccccc cggtccgcgg
    17281 cgaggaagtc ctgcacgtcc cggcgggacg gaggcagcac ctcgacatag cgcagggcac
    17341 gcaggtcctg ggcgaggcgg cgcaggtcgg cctcgtccgt gcggcagccg accgccatcc
    17401 cggggcagga gcggcgcagc cgccgcagct cggcgacgca cctgctgcgc tctggttcgg
    17461 gcacctcgtc caggccgtcg aggacgggca ccagccggtg ctcctgcagc caggtgcgga
    17521 cgaggatgcc ggagacaccc cggtactgct gggccatggc ggcggcgagc cattcctcga
    17581 cgggttcgcc ccggtacgtg tccagccgca ggtagaccgg gacgtgcccg gcactccggt
    17641 cacagggcgc gtccggggcg tccggggtgt ccggggtgtc gagcgcctcc actgccagcc
    17701 ggtgggcgag agcggcgagt tgggtggtct tgcccatgcc ggggcggccc agcagcacca
    17761 ggtcgtcggt gtcctcgtag agggcgcgga gggtggcggc ctgcgcgggg acggccacgg
    17821 gctcggcccg ccgcgcccgt cgggaccggc gggcgcggcc ggcgtggctg cggtcgtgct
    17881 cgggcgcggt gaggatcgcg aaccgcgggg tgaggtagtg gtgggcctcg gcgcgcccga
    17941 gttcgacggc cgtcctgtcc cggacctgtt tgacgagcct gcggcgcagt tgggccgcgt
    18001 acgcgtccct gcgggagcgg gccggccagg cgaggaccgc gagcagccag gccgcgacgg
    18061 cccgcaggag ccggcgcacg gggtagcggc gcagggcggc ggccggggcg tccccgggcg
    18121 gcgccggggc cggggcccgg tcgtcgtcgt cgacgccggg cagcgcagcg gggcgggcgg
    18181 acggcaccgc tgcccggtcc ggtgccggag cccctccggc tgccgggtcc tcgcacgggg
    18241 cggggtcctg ttcggcccag gcccggtgcc agcgcggctc ccattcgcgg gggtcgccgc
    18301 cgagcgcggt gaccatggaa aggaacggcg ccaggcgggg gcggcgcttg ccggagaagg
    18361 actccgagac gtagggcggg ctgaggttcg cggccctggc gagggccgtg accgtggggc
    18421 ggtcggccgg ctcccgggcc tcgtacagct cgtcgtggac gcggcgcatc agctgcgccc
    18481 acacccgcaa ccccggtgcg gccgcggccg gatcggggcg ctgcggcccc cgggggcgcg
    18541 ggccggcacg tcctgtcatc cgctctcctc tttcacgagc cgttcactgc cgttcattcg
    18601 ttcaccgctg cccggaaggc ctggtcgccg gggtgcggcg ggccgtagaa cggtggtcgc
    18661 cgggaccgtt cggggccggc cggcgcagac ggccgcgggg tccgcggcgc gccgcgcggg
    18721 gcgtccgcgt cccgcttcga cacacccatc ttggccatcg cggcgccgtt tgtacggctg
    18781 gttgccaact ccggaagaac cgccgccgat caaggagttc ccatgagcct gcacacaacc
    18841 gtgacacgtg tcctcccctc cctcggcggc ctcgcggccg cgggggcggg cgtgctggcc
    18901 gacgccccct ggtggctggt gggcgtgctg gggttcgcgg cgctgctggt gctgcgggcg
    18961 gaggcgctcg tcaacgcccg gaacgaggcg cggcgcgggt cgcacgagca ccggctcctc
    19021 gcgacggtgt ccggacggca ggcgctggac tacctcacgg aggtcaggcg cgcccaggcc
    19081 gggccggcgg ccgctccggg gcccggggcg gagggcgggg cggccggggg cggcaccgcc
    19141 tgagggcggg tcaggaggaa gggcaacacc gcggcggccc gcgcggcgcg cgccaaggcc
    19201 gacgcgtaca agaaggccca cgaccgcctc gtcgcctgcg agcccggcgt gcgctgctga
    19261 tgccgtgaca gccgtcggcc ggggcccgac ccggacggcg gcaccggact cggcggcagg
    19321 cgcgacacgg cagcggcagg ggccgatggc agccccggag gcctctgctg ctggttgggt
    19381 gagggggcag atccccccca cccgaggatg gatgccatga gcgacgggaa acagcccggc
    19441 gagcccactg cccggcgcat gcgcgaggag gccgaggagc tggagctggc cgcccagcac
    19501 gcctccgacc cggaggaacg ccggcgcctt accgacgagg ccctgcgcat ccgggagcgg
    19561 atcgagcggg agagcggtcc ggaaggcgcg accatggacc ccatgtgatc cggccgttcc
    19621 gctgcgggag accgcggccg cgcgcggcgg ccgcggtctg ccgcatttct ggctactgac
    19681 cagtcacttc gtgtttttgc gccgacctcc gcactacggc gaattcacgc cgatcggctg
    19741 cccggattcc ctcgtgcggc gtttccccgg gtggcgcccg ctcaaccccc tccggcccgg
    19801 cgccgaacgt ccgctcccgc accgaccgcc ccggatcagg tacgcagcgt tgacccttca
    19861 gtaacttggc gctagcttcg cttcgttcac cgaaaggccc gaattaccgt tccgggctcg
    19921 cgcgaccttg tgccttcccg cggccttcgt cctggccgac attcccccac cgggcaacgc
    19981 catcgcatat tcggagaatt atgacgccgg cagagcacgt catcggagtg acccccttcg
    20041 gcgaacccga tgcccgcctc gcggccgcgg tcacccgcgg cggcggactg ggtgtcctgg
    20101 acctcggatc cggtgaccgg gccgcccgtg cggccctggc cgacctgcgg ggctggctgc
    20161 ccgggcggtt cggggtgcgg gtcggcccgc gctgccgatt acgcccgggg gacgcggccg
    20221 ggctgctcgg cggccccggc ggaccccgta cggtgctcct cgccgaagga tccgcggtgc
    20281 ggcccgcgga cgtgccgccc ggggtgcggg tgctggccga ggccaccggc ctggccgagg
    20341 cacgggccgc gctggacgcg ggcgcgcacg gcctggtcgc ccgcggcagc gaatgcggcg
    20401 gccgcatcgg cgaactcggc acgttcgtcc tgttgcagca gctcctggac gccgccggcc
    20461 ccgacgggcc gcccgtgtgg gcctgcgggg gcatcgctcc gggcacggcc gccgcggccg
    20521 tcgccggcgg agccgcgggc gtcgtcctcg acacgcagct ggcgcttctc gcggagtcgg
    20581 cgctccccgc ggccgtggcg gccgtactgc gcccgctgga cggctccgag accaccgagc
    20641 tgggcggcca ccgcttcctg caccggcgcc gggccgcggc ccctccgccc ggcgcgccgc
    20701 ccctcgacct gcccgacgac ccggaccgga tcgcctccct gctcggcggc cgggaccccg
    20761 acacccagct cctcccggtc gggcaggacg cccccctggc cgccgtgttc gccgaccgcc
    20821 accgggacgc cgccggcgcc gtgcgcgccg tcgccgaagc cgtccgcgcc gcgaccgccg
    20881 acggcgccgc aggccgcgcc ctcgccgccg gctcccccat gagccgcgcc ctcggcaccc
    20941 gcctgccgat cgcccagggg ccgatgacgc gggtcagcga cggggcggac ttcgcccgcg
    21001 ccgtctccga cggcggcgcc ctgccgttcc tcgccctcgc cctcgccggc cgcgagcagg
    21061 ccgccgccct gctcgccgag gcggccgccg ccctggacgg ccgcccctgg ggggtgggcg
    21121 tcctcggctt cgcccccgag gagacccgcg ccgcccagct cgaagcggta cgcgcgcacc
    21181 ggcccagcca tgccgtcatc gccggcggcc ggccctcgca ggcccgcgcc ctggaagccg
    21241 acggcataag gacgttcctc cacgccccct cccccggact gctgcgccag tacctcgccg
    21301 agggagcgcg ccggttcgtc ttcgagggcg ccgaatgcgg cggccacgtc ggaccgcgca
    21361 acagcttccc gctgtgggag gcgcagaccc gggtcctgct cgaccacctg gccggggacc
    21421 ccggcgccgc gcccgccctg gaggtgttct tcgccggcgg cgtgcacgac gcccgctccg
    21481 ccgccatggt cgccgccctg gccgcgccgc tcagcgcccg cgggtgcgcg gtcggcgtcc
    21541 tgatgggcac cgcctacctg ttcacgcggg aggccgtcgc ccacggcgcc gtacggcccc
    21601 tgttccaacg gcaggtgctg gccgccgagc ggacagcgct gctgcggacg gctcccgggc
    21661 acgccacccg gtgcgtgccg agcccgttca gcgaggggtt ccggatgctt gcggcggagc
    21721 tgcgcgccgg cggtgcgccc gagcgggagg tgtgggagcg tctggagcgg ctgaacgtcg
    21781 gccggctgcg gctggcgagc aagggcgtcg agcgcaccgc cgccggcacg acggcgcccg
    21841 tcgacgagga acgccagtac gccgagggca tgttcatggc cggacaggcc gcggtgctgc
    21901 gggactgcgc gacgaccgtc gccgagctgc acgagtccgt caccgcgggc gccgcggcct
    21961 tcctggagcg gcggcgtgcc gccctgcggg ccgcggcacc ggaccgggcg ggcgccgggt
    22021 ccggcgggcg tgcgcccgca ccgctggaca tcgccgtggt cggcatggcc tgcgtgttcc
    22081 ccggggcgcc ggacctcgcc gcgttctggg cgcaggtcct ggacggccgc gacgccgtca
    22141 ccgaggtgcc cgcggagcgc tgggacccgg acgtgcactg ctcccccggc cccgacggca
    22201 gcggcccggc cagcgcctcc cggtggggcg gcttcctgcc ccgcatcccc ttcgacccgc
    22261 tgcgctacgg catccccccg gcctcgctcg gcagcatcga accggtgcag ctgctcgcac
    22321 tggaggtgtc ccggcgcgcc ctggaggacg ccggccgcgg cgagggcggc cggcccttcg
    22381 accgggcgcg gaccggcgtg gtgttcggga ccgaggcggg cagcgacctg tcgaacgccg
    22441 ccacgctgcg gaccgtgctg ccgtcctact acgggcgggt gccggccggg ctggacgggc
    22501 agctgccccg gctcaccgag gacaccttcc ccggcgtgct cgccaacgtc gtcgccgggc
    22561 gggtggcgaa ccgcctcgac ctgcgcggcc ccaaccacac cgtggacgcc gcctgtgcct
    22621 cgtcgctggc cgcgctcgac gccgcctgca aggaactcgt cctcgggacg agcgacatga
    22681 tgctctgcgg cggcgccgac ctccacaacg gcatcaacga ctacgccctc ttcacctccg
    22741 tccgcgccct gtccccgacc gggcgctccc gcgcgttcga ccggtccgcg gacggcatcg
    22801 ccctcggcga gggcgtcgcc tgcgtcgtcc tgaagcgcct cgcggacgcg gagcgggacg
    22861 gggaccgcgt gtacgcggtg gtcaaggcag tcggcgcgtc cagcgacggc cgctcgctgg
    22921 ggctgaccgc gccccggccg gaggggcagc gcgccgcgct ggagcgcgcg taccggggct
    22981 ccggcgtgtc cccggccgac gtcgggctgg tggaggcgca cggcaccggc accgtggtcg
    23041 gcgaccgtac ggaactccgg gtgctgacgg aggtgttcga ggcggccggc gcccgcgcgg
    23101 ggagctgtgt gctcgggtcg gtcaaatcgc agatcgggca cacgaagtgc gccgccgggc
    23161 tggccggcct ggtcaagacg gcgctcgccc tgcacacggg ggtacggccc ccgaccctcc
    23221 acctgtcgag accggacccc gcctggcagg cgggcgcgag ccccttcgtg ttccaccgcg
    23281 aggcactgcc ctggccggcc gcccccgggc ggcggtacgc ggggctgagc gccttcggct
    23341 tcggcggcac caacttccac gcggtactgg ccggccacga cgcaggcggg ccgccgccgg
    23401 agcacacccg ggacgagtgg ccggccgagc tgttcctgtt ccgcgggacc gacaccgcgg
    23461 cggcccgccg ggcggcggcc gacctgctgg aggccgccga cgcggcggcg cgcggggaga
    23521 ccccgtggcg cctgcgcgac ctggccgcca cggcggcggg ccgagccgcg cgggcgcggg
    23581 gcggcatccg catcgccttc acggcacggg acctcgcgga gctgtgccgg ctgctgcgcg
    23641 ccgcggcgga cggggccggg gcggacgctg cggccggggc cgcccccggc ggacgggtgt
    23701 accgggctga gggggacggg gccggcggcg ccggccgcac cgtcttcctc ttccccgggc
    23761 agggcagcca gcggcccggt atgtccgcgc acctcttcac cgcctttccc ggcctcgggc
    23821 ggctgctccg cgcggacgcc ggcggccggg ccgcggcggc gctgtacccc ccggccgcgt
    23881 tcgacgacgc cgctcgcgag gagatgcggc gcgccctcac cgacacgcgg gccgcgcagc
    23941 cggccctcgg catggtggag ctcgccgcgt acgagctcct cgcccgctgc gggatccgtc
    24001 ccgacatggc ggccggccac agctacggcg agctggtcgc cctctgcgcc gccggagtcg
    24061 tcgacgcgga ggcgctgccg cggctgagtt cggcgcgcgc cgcggccatc ctcgacgcgg
    24121 tcggcgccga tcccggggcg atggcggcgg tggcggccgc accggaggac atcgggcggg
    24181 tgctgggcgg cccgccgctg cccggggggc tggtcgtcgc caatcacaac gcgccccggc
    24241 agtgcgtcct ttcggggccg acgccggcgg tcgaggcggc cgtgcgccgg ctgggggagg
    24301 ccgggctcgg cgtgaagcgg ctgccggtgg cgtgcgcctt ccacagtccg ctcgtcgccg
    24361 cggccgggca gcccttcggc cgcgccctcg ccgaacagca cctgcacgag ccggagttcg
    24421 aggtgtgggc caaccgcacc gcccgcccct acccggccgg cccggatgcg gtgcgcgggg
    24481 agctcgccgc ccagatcggg gcgccggtgc ggttcgcgga gcagatcgag gcgatgtacg
    24541 cggccggggc ccggaccttc gtcgaggtcg gtccggggtg tgtgctgacc cggctcgtct
    24601 cggacgtcct ggccggccgg ccgcaccgga ccgtcgcctg cgagccgcgg cccgacagcg
    24661 gcctggccgg cttcctcgac gcggtcgccc gcctcgcggc cgccgggctg ccggtggccg
    24721 ccgactggat gttccgcggg cgggacgccg tcgacaccga ccgggccccc gccccgcgca
    24781 cccccggctg gacggtggac gggcacctcg tccgcaccgc ctccggcgac ccgctccccg
    24841 gcgccctggc gccggcccga cccgttgtgg aggcacctgt ggcgacgaac cccggagagg
    24901 cggcgccggg tgcgccggac gcgctggtcg ccgagttcct gcgcagcagc cgggaggtga
    24961 tcgccgcgca gcgggacgtc ctgctggcct acttcggcgg cacggtggag gcggccccgg
    25021 gggccgccgg gccccagtcc ctgccgctgc cggtgccgct gccggtgccg gtgccgctgc
    25081 cggagtacgg gtccggtcag gcggccgctg ccggagccga ccgcggccgc atcggcaggg
    25141 ggccggcgcg ggatgctgcg gccgagcggg cagccggcga cggcgaaacg atcctgcgga
    25201 cggtcctgga gctgatcgcc gaacgcaccg gctatcccct cgacatggtc gagccggacc
    25261 tcgacctgga gtccgacctc agcgtcgact cgatcaagcg cgccgagatc gccggtgaac
    25321 tcgcccgcag gctcgccccc gcggacgccg ccgggcccat ggcgctggac gacgcggaac
    25381 tggaggaact ggcgcgagcg cgcacggcga ccgcgatcgc cgcctggctg gccgcccgtg
    25441 cgaccgccac cgcgcccgcc gacgcgcctg gccccgcgcc cggccctggc tccggtgctg
    25501 cggaggaacc cggggccggc ccgggagcgg gccacccggt cgacgacgcc cttgccgacg
    25561 cccccgcggc cgcggccggt gcggtgactg ccgccggggc acgtgccgcc gccggcgcga
    25621 cgcccgatcc cgtgggggct gcgccgcggc ggtaccgggt cgtgcaggcg gaggtcgtgg
    25681 gcccccggcc cgggcccccg gaccttgccg gaagccgctg ggcggtcctc ggcgacgggg
    25741 ccggtgcgtg gcgcggtacg gccgcccggc tggcggcggt gctggacgcg cagggtgccc
    25801 tccgggtgga tcccggtgaa ggcggcgacg gcttggccgt ggcggacggc gccctcgacg
    25861 gtgtcgtcgt actggacgcg ctcggtgagg cgggcgggcg ggccttcctg ccggacgggt
    25921 tcggtgtcgt acgggcggtg ctgcgcgccg gtgcgcggcg cctgttcgtc gtccgggagg
    25981 ccgggtacgg gttgcgggcg gccggggtgg acgggctggt gcgggccgcg gcccgcgagt
    26041 atccggacgc ggtggtgcgc tgcgtggtgc tcggtgcgga tgccgcgccg gggcccgagg
    26101 gcgccgtcga ggccttgctg gaggaggccg ccgcgggcgg cggtgagccg gtcgtgctgc
    26161 ggacgcctgc gggccggttc gcgccggtgc tggtcgaggc gccgctcggg ccgctcgccg
    26221 gcaggggtgc ggggccggcc ggggcgggcg ccgcggaggc ggaggcgctg gggttggacc
    26281 gggatgccgt cctcgtcgtg gtgggcggcg cccgcggcat caccgcccgg tgcgtggcgg
    26341 tgatcgcggc cgcggcccgc tgccgggtcg agatcctcgg ccggaccccc gtgcccgccg
    26401 ggccggagga agcgctgacc gcggccgcgg ccgaccgggc ggacctgcgg ggcgtcctgg
    26461 ccggcaccgg ccggtacgcc tcgcctgccg acgtcgagcg cgccgccggc ctggtcctgg
    26521 cgcggcggga ggtggcggcc acgctggacg ccgtaatggc agccgggggc ctggcccgct
    26581 accgcagcgt ggactgccgg gacgcggcgg ccgtcctcca ggccgtcaag gagatccacg
    26641 ccgagcacgg gcggatcgac ggggtggtcc acggggccgg catcgtcgag gaccggctga
    26701 tcgccgacaa gtcgccggag tccttccgcc gcgtccacgg gacgaagacg ctgagcgcgg
    26761 ccgcgctcct cgcggccgtc gagcagctgc ccgagggcga acgcccgcgc ttcgccgtgc
    26821 tgttcggcag catcgccgcc gtcctcggca accgcggcca gaccgactac gcggccgcca
    26881 acgacgcgct ggaggcgtac ggcgcggcgt gggcggcgcg caccgggctg cgggcgctga
    26941 cggtgcactg ggggccgtgg gctccgtcgc ccgtccacgg cggcatggtc gcaccggagt
    27001 tggcccggca ctacgcccgg cggggggtgc gcctgatcga ccccgaggag ggagctcagg
    27061 ccctgctgcg ggagttggcg tggggcgacc cggcggagcg ggccgtcgtc ctgagcgcgt
    27121 cggagtggtg acggtggact ccccggcccg cgccccgtac gggggcggca cgcccgcggt
    27181 gcccgtcgcc atcaccggca tgtccgtgct gctgccgggc acgcccgacc tggccgcgta
    27241 ctggcgccac ctgtgcgccg gtgcggacct cgtcggggag gtgccgcccg gacgctggga
    27301 cgccgcctac taccacccgg ggagtgcgcc cgaggcggct gccgccgacc gggtgtactg
    27361 ccggcgcggc gggttcgtgg acgcggtcgc ggaggtggac cccacccgcc tgggggtgat
    27421 gccgtcctcc gtgcccgcca ccgaaccgga ccagctgatc gccctgcacg tggcggcgaa
    27481 cgcgctggcc gacgccggcg ggcccggccg gctgccggac cgcgagcgcg tcgggatcgt
    27541 cctggggcgc ggcggctacc tcacgcccgg gctggtccgc ctcgaccagc gcgtccgcac
    27601 cgcccgccaa ctggtgtgca cgctggccga gttgctgccg gggctggatg cggaccggct
    27661 ggaggaggtg cggcgggcgt tcaccgagcg gctgggcccc gaccggccgg aggacgcgat
    27721 cgggctggtc ccgaacctgg ccgcctcccg ggtcgcgaac cggctggacc tgcgggggcc
    27781 ggcgtacacg gtggacgctg cgtgcgcgtc gtcgctgctg gccgtggacc aggcggtctc
    27841 cgcgctggcc gacggccggt gcgacgtgat gctggccggg ggcgtgcacc actgccacga
    27901 catcacgctg tggagcgtgt tctcgcagct gcgcgccctg tcgccgagcg agcggatccg
    27961 ccccttccac cgcggtgcgg acggcctgct catcggcgag ggcacgggcg tggtggtgct
    28021 caagcgcctc gccgacgcgg agcgcgacgg cgaccgcgtc tacgccgtgg tccgcggtac
    28081 gggcgtgagc agcgacggcc gcgcctccgg cctcgtgaac cccgatccgg ccgggcaggc
    28141 acgggccgta cgggcggcct ggcgggccgc aggcctcgac ccggccgcgc cgggctccct
    28201 cgggctgctg gaggcgcacg ggacggccac cccggccggc gacgccgccg aactcgccac
    28261 cctgcaacag gtgttcgggc cgccggacac ctcgcagggg gcgggccggc ccgtgctcgg
    28321 ctccgtgaag tcgatgatcg ggcatgccat gccggccgcg gggatcgccg ggctcgtcaa
    28381 ggcggcgctg gccgtgtacc acggcgtgct gctgccgacc ctgcactgcg aggacccgca
    28441 cccggcgctt gcccggacgc gcttccgccc gctcgcgcag gcggccccgt gggaggaggg
    28501 gccgggcggc gggccgcgcc gggcgggggt caacgcgttc ggcttcggcg ggatcaacgc
    28561 gcacgtcgtc ctcgaacagg cccccgcctc cgccccggcg gccgcgctgc ccctcccgcc
    28621 ggggccgcgc gcccggacgg cggtcgacga gccggagcgc gtcctgctcc tggccgcgga
    28681 gacgcccggc ggcctcgccc gcctcctcga cgcgcccgat ccggcggtac acgccgaagg
    28741 gcaggccgcc gccccggcga agccggtgcg gctggccgtc gtcgggccgt ccgcggagcg
    28801 gctggccctg gcccggcggg ccgtcgccaa gggcgcgccg tggcacggcc gcggcgacgt
    28861 ctggttccgc cccggccccc tgctcggggc ggcctcaccg gggcccggca ggacggtgtt
    28921 cctcttcccc ggcctggagg ccgagttcgc tccgcgcgtc gacgaggtcg ccgaccggtt
    28981 cggtctgccc cgcccgccgg ccccgccggg ccccgcagcg gacgggcctg ccgcggtcgg
    29041 cgggctgggc cggcacgggc tgggcgtcgt cgccgtcggc cgcctcctcg acgccgcgct
    29101 gcgccgcatc ggcgccgtac cggacgcggt cgccgggcac agcgtcggcg agtggacggc
    29161 catggccgcg ggcggactgt acgaggagga ggcggtggac gcgttcatgg ccgccctgga
    29221 cccagaggcg gtccgggcgg ccgacctggc gtacgcggcc gtcggcgcgc acgccgaccg
    29281 ggtggcggaa cggctggccg ggggcggtca cccgggggtg gtcgtctcgc acgacaacgc
    29341 gcccggccag tgcatggtgt gcggaccgcc cgacgcggtc gggcggttcg ccgccgaagt
    29401 gcgcgccggc ggcgtcctgg tgcggaccct gccgttccgc tcgggtttcc acacgccgat
    29461 gctcgcgccg tgcatcgggc ccttccggga ggccgccgaa cggctgccgc tgcgcacccc
    29521 gcacaccccg gtctggtcgg gcacgacggg ccggcctttt ccggccgacg cggcgggggt
    29581 ccgcgagctg ttcgttcgcc acctgctgga gccggtccgc ttccgcgtcc tcaccggctc
    29641 cctgtacgag gccggcttcc gcgtcttcgt ccaggtgggc ccgggacagc tcggctccct
    29701 ggtcggggac accctggcgg cgcgcgacca cctggtcgtc gccgcgaact cggcgcgccg
    29761 cgggggtctg gcccagctgc ggcgggtggc ggccgcactg tggacggccg gcgccgccac
    29821 ggaccccgag gccgtggacg ggcgggatgc cgggccggag cgcacggcac gtcccggcgc
    29881 cgccggggca cgcaccgggc gcccggtccg gctggacctc ggcgcggcgc tggtgtcgct
    29941 gcccccgtcg gcccgaccgc ccctcgcacc gcacccctcc cccagcgcgg tcgcagctgc
    30001 ggcatccgcg gccggcgggc ccgtggccgc cgagttggcg gcgctgctgg acgagacggc
    30061 gcgcacggcg cagaccgccg ccgcgctgct cgccggggcc gggcggccgg gcacccgcgt
    30121 acgccggcgc gcgcccgcgg cgcccgctgc gcgccgggag acggtgcggg tgtcggtgga
    30181 gcacatgccg tacctgctgg accactgctt cttcccgcag cgcgcggact ggccggacgt
    30241 ggcggaccgg tggccggtgg tgccggcgac gacgatcacg gcgctgatga aggcggcggc
    30301 ggagcgtgcc gctccggggc gggcggcggt cgcggtgcac gacgcgtgct tcgaccggtg
    30361 gctgacggcc gccgagccgg tggacgtccc ggtctccgtg gccccgtgcg gcccggaccg
    30421 ggtggcggtg tcgttcgggc cgcatgcgcg cgccgtggtg gagctggccg gccggtggcc
    30481 ggcggaaccg ccgcccgcgg tgccggccga cccggcgggc gagcgggtgc ccgaccacac
    30541 cgcggaggag gtctaccggg agcgctggat gttccacggc cctgcctacc gggggatgag
    30601 ccggctcacc gccatcggcg accggcacgt gcgggccgtc ctgacggtgc cgcccgcacc
    30661 gggcggtctg ctggacaacg tgggacaggt cctcggctac tggatcatgg cgacgcgcac
    30721 cgagcggacc gtcgtcttcc cggtccgggt gcggcagatg cgcttccacg gcccggaccc
    30781 gcggcccggc acccgggtgg agtgcacggt gcggatcacg tccctgacgg acaccgtgct
    30841 ggaggcggac gccgtgctga cggtggcggg ccgggtgtgg gcggagcttt cgggctggca
    30901 ggaccggcgc ttcgacaacg atccgcacac ccggccggtg gagcgcttcc ccgaccgcaa
    30961 caccctctcg gtggccgggc ccggcggctg gtcgctggtg ttcgagcgct ggcccgacct
    31021 ggcgtcccgc gagctgatca tgcggaacgc cctgggcggg ccggaacggg ccgcgtacgc
    31081 cgcccggccg ccgcgcggcc gccggcagtg gctgctgggc cggatcgcgg cgaaggacgc
    31141 ggtgcgccgc ctgctgtggg aggccgggga ggggcccgtc ttccccgccg aactcctcgt
    31201 ggagaacgag ccgtcggggc ggccgcgcgt cacgggccgg tacgggcgca cgctgccgcc
    31261 gctgcgggtg tcggtggcgc accgggccga ggcgggcgtg gcgctcgccc gcgccgccga
    31321 cgccccggtc gggccgggac cggggccggg catcgacatc gaggagatcg ccgagccggg
    31381 cggcgcgacc gcggcgaccg tgttcggggc ggcggagctg gccctgctgg cggcctgccg
    31441 ggccggctcg gcggagcctg cggacgtgtg gttcacccgg ttctgggcgg ccaaggaggc
    31501 cgtcgccaaa gcggagggca ccggactgcg cggccggccc cgggacatcg aggtgacggc
    31561 ggcggagccg gaccggctga cggtccgcgt ccgccgccgc acggacgcgg ccgacccgcc
    31621 gggcgcgccg ggcccgccgg ggggcccgta cggcgtgtac cgggtcggct gcacggaggt
    31681 ggccaaccct ccggggctgc cgccgcgcgc gtacgtcgtg gcgtggacga ccggcccgga
    31741 cccggatccg ccggggccgg gcgccgaccg tgacgagggg agcgaagggt gacgacgagc
    31801 agcgggcccg atccgtccgg gggagccgac gaggcggagg tgctcgccga gctgaccgcc
    31861 atgatccgac aggtgctgga gggctacgag gtggaggagg gcgaggtcac gatgcgaacg
    31921 cgcttcggcg ccgatctcga actggagagc atcgacctgg tgacgctcgc cgggctgctg
    31981 gaggagcgct acggcggcgc ggtcaacttc gccgagttcg tcgcggacct ggacctggag
    32041 gagatcatcg agctggacgt gggccggctc gtggaccaca tccgccggtg cctgaaggcc
    32101 gcggacgggg tggggacgcg gtgaccgtcc tcgacaccgg ccgggtccgg ctgcacgtgc
    32161 agcgcctcgc accgccggac ggccgccccg cgcgggccac cgtggtgctg gtgcacgggc
    32221 tgctcaccga cagcctggcc agctactact tcaccatcgc cccggccctg gccgcggcgg
    32281 ggctggacgt cgtcatgtac gaccagcggg gccacggccg cagcgagcgc ccggcccgcg
    32341 ggtacgggct cgacgacgcg gccggggacc tggacgccgt cctgtccggg ctgggggtgc
    32401 gggggccggt gcacctggtg ggcaactcgt acggcgggac ggtcgcgttc gcgtacgcgc
    32461 tgcggcgccc ggagcgggtg gccggcctgg tggtggtgga gtcggagccc gcgaccgccg
    32521 cgtgggcggc caagctggca ggcctgctgg agcgggtccg ccacgagatg accgccgacg
    32581 aggatgcggc gctcgcctgg atcgccgccc accacggcgg gcacaccgcc cgcctggcga
    32641 gggccgccgg gcggctcgta cgggacacca gcatcgccgt ggacatcccg gccagcccgg
    32701 tgctcgacga cgacgcgatc cgggccctgc gctgccccgt cctggccctg tacggggccg
    32761 agtccgacct cgccgggcag gcgccccggc tgcgggcact gctgccgcac tgcaccgcgg
    32821 agctggtgcc ggggctgcgc cactcggtcc tggtggaggc gccggcgcgg gtgcgggacg
    32881 cggtcctcga ctgggtcggc cgcaccaccg cgcccgcggc ggcggagcgg cagccggccg
    32941 ccgccgggcc gcgggtgcac gcccggtgag cgccttcctc ctcgtggtcc cgccgctcgt
    33001 cgggcacgtc aacccgctgg tgggggtggc gtccgaactg gccgcccggg gccaccgggt
    33061 ggcctgggcc ggcgacccgg tgctggtccg gcggctggcc ggaccggacg cggccgtcca
    33121 cccgtgcgcc cggagcggcc cggaagacgg gggcggcggg ggcggcggcg ggacggaccc
    33181 cgtacgcccg cccggcatgc gcggcccgga ggcgctgcgc ttcctgtggg agcgcttcct
    33241 ggtgccgctc gccgaggcca tggcgcccgg ggtccgcgag gcggtcgggg cgttccgtcc
    33301 ggacgcggtc gtcgccgacc agcaggcgct ggccggggcg ctggtcgccg aggacctggg
    33361 gatcccgtgg gcgacgtcgg cgacgacgtc cgcggagttc gcggacgcgc tcgccccgat
    33421 gccgcgggtc gccgcctgga acgacgcgct gctgagcggc ctgcgccggc ggatcgggcg
    33481 tccgggcggc aggtgcgacc cgcgcttctc cccgcacctc gtgctcgcgt tcagcactcc
    33541 cgagctggcc gggccggtgc tgcgcggcgg cgagcggatc gcctgggtcg ggccgtccct
    33601 ggcggcccgg ccgcgcccgg cggcgttccc gtgggagcgg ctcgatcccg ggcgcgccct
    33661 ggtgctggtg acgctgggga ccgcgaacgc cggcgccggc ggccggttcc tcgccgaggc
    33721 ggcggcagcc gtgcgggcgc gggccggggc cgtgcagggc gtgttcgccg atcccgacgg
    33781 cgtactcggc gcacgggagg acgatccgga tgtcgtcgcg ctgccgttcg tgccgcagct
    33841 cgacctgctg gagcgggccg cggccgcagt ctgccacgcc ggccacaaca cggtgtgcga
    33901 ggcgctgtgg cacggcgtcc cgctggtcgt ggcgccgatc cgcgacgacc agccggtggt
    33961 cgccgcgcag gtcgaggggt gcggggcggg cgtgcgggtc cgcttcgggc gggccggtgc
    34021 cgccgcgatc ggcgcggccc tcgacaccgt gctgggagag ccgcgcatcc gggcggcggc
    34081 cgcgggagtg tccgccgcgt tccgggcggc ggggggcgcg gccgcagcgg cggaccatct
    34141 ggaacggctg gcccggacag gcgccgggga aggggaggac ggatgagcgg gcgcagggag
    34201 cgcgcggccc gggtggccgc gctgcgcgcg gtgtaccggg aggaactcgc ggacggtacg
    34261 gcggtgttct tcgagccgcg cgcgcaccgc tgcccgtggt gcggctccgg ccggctggga
    34321 ggccggctgc gcaccgcgga cctgttgcag cacaagccgg gcgagttcgc cctggaccgg
    34381 tgccacgact gcgggcacgt cttccagaac ccgcggctga gcgagcgcgg actggccttc
    34441 tactaccggg acttctacga cggcctgggc gaggagcgcc tcgccggggt cttcgcgggg
    34501 cgtacggcct cctaccgggc gcgagccgag tcggtgcgcc cgcacctggc cggtccggcg
    34561 gagtggctgg acgtgggcac cgggcacggg cacttctgtg cgacggccgc ggagctcctg
    34621 cccgacgtgg cgttcgacgg cctggaccgc tccgacgggg cggagctggc cgagctcgcg
    34681 gggcgggtgc ggcacggcca ccgcgggacg ttcgcggagc tggcggagaa ggcgcccggg
    34741 tcgtacgacg tggtgagcat gttccactac ctggagcacg cgccggatcc gctcgccgag
    34801 ttggaggcgg cgtacgcggt cctgcggccc ggcgggctgc tcgtggtgga cgtgccggac
    34861 ccggagagcc gctgggcgcg gctgctgggc cgctggtggc tgccgtggct ccagccgcag
    34921 cacctgcacc tggcgccggc gggcaacctg cgccggaggc tggacgcgtg cgggttcacg
    34981 gtgctggcgc aggagcacgc gcaggcacac gacgcggtgg acctggtggc ggcggcgtgg
    35041 ctggcgctgg acgcggcggc gccccgggag gacctgccgt ggctgccgga gccgccgggg
    35101 ccggcccggc gggcgctgcg gggcgcgacc ctgctggcgg gggtgccgct gctgctggcg
    35161 gcgaccgtcc tggaccggac ggtggcgggc ctggcggcgg agcggtgggg gctgacgaac
    35221 gcctaccggc tggtggcccg ccgcgaggcc cggcctgacg ccgcaccggc gacggccggg
    35281 ggatgaaccc cccggtcccg ggcggcgtcc ggcccggtgc gagactgtgc cccggcccgg
    35341 acgggagcgt ccgggccggt ggtacgggcg gcggacggcc ggcaggaggc gcagttgggc
    35401 accagtgtcg agggacaggt cgacatggcg ggaccggtgg gcaagctgct gcaccggcgg
    35461 aggctgcaca actccacggt gatgcagtcc ttcggcgtcg accctgtcac gggggacgtc
    35521 ttcgtcctcc aggtcgtcga aggcggcctc accctccccg gcgagtccgg cccccggacg
    35581 ggccgacagc gcgcgtacgc cggcgacctc gccgtgaccc ggctcgacca ggcgggcacc
    35641 gtcaccgggc acatgtacct gcggggcttc ggccacggcg tgtccatggg cgtcgagcac
    35701 gacggcggcg tctcgcgcct gtggaccgag accgcgtccg tcccgatggg ctcgaacatg
    35761 cccgaggagg agaaggacgg ctacggcacc gccgtcacgc acttcgagtt ccgcagcggc
    35821 accaccctct cccagggctc ggcgcagctc gccccggcgt accggccggt gtccggcgcc
    35881 acgaacgtca cctgcaccat cgacccgacg acgaaccgcg tcatcgtccg cttcaagagc
    35941 ggcggcatgg tgttcgagtc gtacgacctg gaccgggccc gggccggtga ctggactccg
    36001 gtcgcccgga tcgcccagcc ggacgcgaag ggcaccttcc aggggtacgc ctccctgggc
    36061 cgcgtcctgt acatggtggc cggcagcggc tattcggaca ccgtgaagcc gccgggcaac
    36121 acctggctga cggccgtgga ctggacggac gggtcggtcc tcgaccagcg gttcaccacc
    36181 gccgcccccg gcctggagct gcgggagccc gaggggatgg ccgtctcggt gcgcggcggg
    36241 gtgccgcacg tgcacgtcgg gttcgcgggc gaggagcccg gccctcgcac ctgcacgatc
    36301 gtgtcgttgt cgggggcgcc cgaggtcggc ggggtgaagg tgctggccga ctggcagccg
    36361 atccccctcg cgagcggcgt caccgcggac gtgcggcccc cgcgcggacg cctcgtcgcc
    36421 atcgcgggta cgacggtgct gcagctgagc ggcggggtga agggcacctt cgaggcggac
    36481 accctgatcg gccggctgcc cgacgccctg gctccgagca tggcggccca gtgcagcgtc
    36541 ccgcgcaaca acagcggcgg ggtgtgcacc gcgcgggcgg aggcgaactc gatccgcgag
    36601 ctgtggctct acggcgggcg tacggcgaac ccggtcacgt gggcgcagct ggacaactac
    36661 agcgccgtct ggcgctgacc gcacagcggc ctccaccgtt ccccgttccc tccgtccccc
    36721 gttccctccg tcccccgttc ccctttcccc gtacggccga ggagaccgcc cagccatgac
    36781 ccacaaccgc cgccgcatcc tcggcgccgc cctcgccctg cccgccgcac tgaccgccgc
    36841 cgaggtgctg tccgccgcgc ccgccgtcgc cgccggcggg gtcgaggctc agccgtggac
    36901 ggacctcgtc ctggaacccg gtgtcaccgc ccgggcgggt gcggtgccgc aggtccggct
    36961 ggtcacgatc gccggtacgg ccttcctgca ggcgcgcggc tcggtggcct gcagcctgac
    37021 cgccgatcgg aaggtcgcca cgctgcctgc ggcgctgcgg cccaccggcc tcgtccgcgc
    37081 caccgcgccg cgcaacaaca gccagggcat caacgcctgc cgcttcgagg tcaacaccgc
    37141 cggttccctg accatctacg gcggcaactc cgggaacccg atcacctggg tgcagttcga
    37201 ctccgtgcag acggtctggc actgaacggc agccggaccg tccgccgccg tcacttctcc
    37261 gtgaagacga tctcccggca cgagcgggtc atccgcacga tgttgtcggg ggtgacctcc
    37321 acgatgtggt gcaggccccg gtagagccgc ttggtgtcgg gcaggaggcg gtactcgtcc
    37381 gccgccccgg cgaggaaggc gcggaagcag tccgccgacg ggctcgggtc cccggtgaag
    37441 tcgaggtagt ccttcaggcg gcggaacagc ttcggcagga tcaccgcccc ctcgcggtcg
    37501 tgcgtgatcg acttcttgcc ggtgacaggg aagccctgga gggtcctgtc gaccgcccac
    37561 acccctgcgg ccgacgcccg tgccttctcc gcggcctcgg tgagcagctc gcgcaggtac
    37621 accgggaggc cggagtagaa cgccgggtag gccagtccgc gttcgaggag gcggtggttg
    37681 gcggtccgct ccagcagtct cgcgctgacg ccggtccagt agccgctgta gacgggaggg
    37741 gtgccgcggc cgacgaacgc cacgcagcgg ccgtacgcgt cggcgccgcg ggtgaggatc
    37801 cagccgggca cgctgtccgg gacggtggcg agggtctcgt cgtcgtcgcg caggaccgtg
    37861 ccgaagccga gggtcttcag cagttcgtcc gcggcctcgt gggccagcgg gcggggctgg
    37921 tggtcgacgg gggccggctc ctggccgtag tgggtctcca gggcgtcgat gccttcgagc
    37981 cggatgctcg cgcgcccgtc ggcgccgggg acgacctgcc cgccgggtac aagcttccag
    38041 tcggcgacgt cgtcggggat gaaggggagg gtgtcgccgt cgggcttcgg gcctccctcg
    38101 accttgaacc tgcccctgat cagcagcatg gacatgaggg ctcccctcca catcactgtg
    38161 cgcggtcgtc gctcacgcac agtacacacg ggtggggtcg ccgtgtcggg gccgcgcccg
    38221 ccggcccccc gtgtggcgtc cacgggcccg ggcggcgctg cggctgtccg gggctggtgc
    38281 ggggcggtcc ccggtcccgc gtggggtggg accggggacc gccgtgtcac cggggagcgc
    38341 ggccgggggt gcgtccgctg ctagagggcg cggacgaccg ccttgccgtt cgaggagcct
    38401 tccttgcagg aacgcttctc cgcggccgtc atcttccggg tcttgaccac gacggcgttg
    38461 ctcttgccgt ccgtgccgtt cttggccggg ccggtgatcg tgtcctggaa gaaccagtag
    38521 tagtggcccc acttggggct gtcgtagtgg gtctgccacg tgccggtgac cttctgcatc
    38581 acctgggcgc gggatatcca gcccacctcg cccggcttca ccgtcatgtt gagcgagctg
    38641 ctctcggagt ggctgctcga ccaactgtgg ctgtaactcg ccgtaacact caggtcgacg
    38701 agcccggcga tgttgccgcc cgccgtgacg gacacaccca gcgagtccgt cgcgccgacc
    38761 gtgtcgtccc aggtcatcga ctgggtggcg tcggacgtgc tgcagttgta gagcgagttg
    38821 gagacctgcc ggaactcgcc caggtacgcc tcccccagct tcggggagtt gaacgtgcac
    38881 ttgccttcgc ccgaccggca gtccgccatc agcagcttgc gggtgggctg gtccgcggcg
    38941 gccgccggga gggccgtcgc cgcggcgacc gcgcacgccg acagcgccac ggagagcgcg
    39001 cgggccgtgt ggcgcttgac gcgggttgtt gtcatcgagg tacctctcac cttgctgggg
    39061 ggatcagtga acggctgcgc cccgggcaca cgttcgaccg cggcccggct gcgcgttcga
    39121 tcaccgcctg ttgcgaggtg agattcttcc gatgccgggc aggggcacgg cggaaatgag
    39181 ccactcctgc cggtccccca ccgtgccccg cgcggaaaat tcctggcgga tccggccggg
    39241 gcggtctacg ctcgccgcga tgaagacttc tcctctgcac cgattggggg aaccgtccgc
    39301 gcaaggtgag tgctgatggc cactcacctc ccggacgacg actcccgtct gtccctctgg
    39361 ctgcgcgtgc gccggtacgc cgtgccgccc tccgtgatcc acaccgcgac cgcccgccgt
    39421 tccgccggcg actgggcggg ggcctgtgcc gccgccggcg tggacgtcga cctgcacctg
    39481 ccgtccgtgg cccggaccta cggccgcgac tgcgccgccc ggctccgggc cgacctccgc
    39541 cacctggcac ccgacctgct gcgctggcac atgccgcgga ccgcccccga cgggctgctg
    39601 cgccccggcc tgaccgtcgc cctggcccgc tacgccggga ccgggcccga cggcacgggc
    39661 tcgctgtacc tcgtggtgcg tacgccgccg gcctgggcgg acgccggcca gcggatcgtg
    39721 ctcgggctct gggaccggtc ccggcccgag gccgcgcccg ccgcccgcaa ccacccgcat
    39781 ccgcggcccg cgcggcggtt ccggctcgac ctgcaccgcc acctgtggga cgcgcgcagg
    39841 gcgggcgaac tccggcaccg ctcgggcgcc gaccggccgc cgggcaccgc gcccgcgccg
    39901 gcgctcgcgc tgccgcccgg gcggtcggcc tccgccgcgc cggcgtaccg ctgcgccccc
    39961 gacctgtggc ccgacgaggc cgggctcctg ctccgggccg acggcctgga gcccgggccc
    40021 gtcgaggtgc gcctgggcag ccggcaccgg ctggtcatcg acccggccac cggccggccc
    40081 gcggcggcgc ccgcgggcgg actccggctg cccgtactgc ccgacgcggc ggcgtgggta
    40141 ccgcccgacc tggagctgct gcgcgccggg ctgatcggac ccgaccggct gcaccccctc
    40201 gtcgccggcg cgctcgtacc cggccacgtt ccggccggcc cgccgccggg cgccgaaccg
    40261 gacgacgggc cccgccacgt ggactgccgg gggtccaggc accggatcgg gctggtcgac
    40321 ggtgtcctgg ccgcactgga ccacggcccg gacgaactcc ggcgcgagga actgctggtc
    40381 gccctgaccg gcactccgct gccctgcctg cgggccatcg accgggcgca ccgccggccc
    40441 gagtcgctgc ccggcatccg cgagcgcctc gcccacggcg acaccgccgg ggcactggag
    40501 gccgtcgagt ccctcctcgg gcccggggcc gtcctccggg acggcctgct gcgggacgag
    40561 ctggagtcgg cggcccggca gcgcatcacg tacgggctct accgggccgg cttggtcggg
    40621 cccggccccg ggcgcggccc ggccggggcc ggtggcgagc cgccggcgcg gcgcgtccgg
    40681 ccctcccgcg cccggcagcg cacctcggcc ctcttctact gacccctccc gacgacggcg
    40741 gcggcgcccg cgcgccgcac cgccacccgc tcccttcccc gtgcgcgccc gcgcgctccc
    40801 gctcacacac acccacggtg attaccatgc cttccaccct gtccgctccc gccccgtccg
    40861 ctcccgcccc ggcgcagctc gacgtcgcct ccgagctgct ggcgctgctc cgcgacacca
    40921 ccaccgagcc gcgccccgac gtacagctgg aagccctgac cctggccgtg gccgccgacc
    40981 tgcccgtcct gctgtggggc gaaccgggca tcggcaagac cgcggccctc acccagctcg
    41041 ccgagaacct gggcctcccg ctgaccacgg tgatcgcgag cgtgcacgag ccgtcggact
    41101 tctcgggcct gcccgtcatc ggcgacgacc ccgccgtgca gggcgtgccg atggcgccgc
    41161 cggactgggc cgtccgcctg gtgcgggccg gccgcggact gctgttcctg gacgagctgt
    41221 cgaccgcgcc gccggccgtg caggccgccc tgctccgcct tgtactggaa cggcgcatcg
    41281 gctccctccg gctgccggac ggcgtgcgca tcgtggccgc ggcgaacccg cgtgcgtcgg
    41341 cggccgacgg atgggagctg agccccccgc tggcgaaccg gttcgtccac ctgcagtggg
    41401 tgcacgacca cgacgtcgtc gtacggggcc tcggcgggac gtggccgcgg gcgacgctgc
    41461 cgcagctcga ccccgcacgg ctcgcggacg ccgtggacct cgcccgccgg gcggtgtgcg
    41521 ggctgctcgc cggacgtccg gcgctcgtgc accggctgcc ggccggggag acgcgccgcg
    41581 gcggggcctg gccgtccccg cggagctggg agatgacgct gcgtctgatc gcatttgcca
    41641 ccgcggccgg atcctcccgg gacgtcctgt ccctgctggt gcgtggcgcg gtcggggacg
    41701 gtccgggact ggagctgctg gccggcctgg accggatgga cctgccggac ccggaggacc
    41761 tgctggcgga tccggaggcg gccgtcctgc ccgagcgggg tgacctgcgg caggccgtgc
    41821 tcgattccgt cgtcgcggcc gtgcgcagcc gccccgagaa gtcccgctgg gacgccgcct
    41881 ggacgctcct ggtgcgggcc gtcgaatccg gggcccccga cctggtggtg gttcccgcga
    41941 ccacgctcgc ctcgctgcgc cgcgacgcgt gggacgtccc cgaggcgatc gaggagctcg
    42001 ccggggtggt ggccctctcg cgccgcgccg accgggcggc ggcgcggacc gcgcccggcg
    42061 cgaaggccgg ccgatgacgg gcgcggcgga cacggcggac gccgcaccgg gagcgggcgg
    42121 gccgtcggag gcggagccgg gcggggccgc gcccgcggcc gccgactcgg acggggactc
    42181 cgaccggggc ctggacctgg acaagctgta cgccgcccgg ctgcaggcgg cgcgggcccg
    42241 gccgtatgtg gcgacggccc tgtacgccct gcatgccgtc ccgtcgcggc aggtgccgac
    42301 gatggcggtc gaccggcact ggcggtgcta cgtctccccc ggcttcgtgg accgcacgcc
    42361 ggtggaggag ctcgccgccg tgtgggtgca cgaggtgtcg cacctgctgc gggaccacca
    42421 cgggcgcagc gaccgggtgg cgcggcagca gggcctcacc ggccgggccg agcggctgcg
    42481 gatgaacatc gccgccgact gcgagatcaa cgacgacgcg ttcggcgacg ggctggtcac
    42541 gccggagggc gccgtcctgc cggagacgct gcagttgccg gaggggcagc tgatggagga
    42601 ctacctccgg cagttccggc tcggaccgca gttcgggcac ctgtcctggc tggactgcgg
    42661 cagcggcgcc gacgggctgg accggcagtg ggacctcggt cgggacgggg cgcacgggct
    42721 cagtgcgcag gaacgcgacg cggtccggtt ccgtgtggcg cagggcatca agggccggcc
    42781 ggggaacgcc ccgcggcagt ggcagcggtg ggcggaggag gccttccatc cgccgcagcc
    42841 ctggcgggac ctgctggggg cggcgatccg ctcggccgtc tccggctcgg gcgccggcga
    42901 ggactacagc tacggccgcc cctcgcggcg gtcgtccgca ctgcggggca cggtcctgcc
    42961 cagcctgcgg cgccggccgc cgcaggtcgc cgtggtcatc gacacgtcgg gctcggtgag
    43021 cgacgccgag ctcggcggtg cgctcctcga agtcgccgcg atatgccggg ccgtgggcgg
    43081 ccgccgggac ctggtgaccg tactgacctg cgacgccgcg gcccgggtcg tggggccgct
    43141 gtgccgggcc gaggggatcc cgctggtcgg cggcgggggc acggacctcc gccggggctt
    43201 cgcgcgggcg ctgcggtccc gcccgcggcc cgatgtcgtc gtggccctca ccgacggcca
    43261 gacgccctgg ccgtcggacc ccccgccgtg ccggacggtg gtgggcctct tcccccgccc
    43321 ggccccgccc ggcacccctt gcgaggacga ccccgactac cggccggacg agccgccgca
    43381 gtgggcccgc gtggtcacac tcggctgacc ccgcctgcgg ggcgatcggt ccgctgctcg
    43441 ccgtcgtccg gtcaggccga cgccgcagag cggcctctcc gtacggggtc tgcacgacgc
    43501 cccggtcggc ggaacggggg acggtggggg cggccggggg tgatgcgggg cgtgtcgtgc
    43561 gggggtgccg ggcggccgag ggggacgatc ggcgtccgtc gggtcccccg cggaggaatg
    43621 aggacggaat gcgcgagatc cgctccggcg gccggcacgg gaccggctct ccgttgcgcg
    43681 ggcgggtcgc ggtcgtcacc ggtgccgccc gcgggatcgg ggcggcgctg gcgcggaacc
    43741 tgtcggagtc cgggatgcac gtggccctgc tgggccgcga ggaggcgtcc ctgcgtgcca
    43801 cggccgccac cctgccgcac cggagcatct gcttcgaagc ggacgtcacc gacgacgcgg
    43861 ccctccgcgc cgccgcccgc tacgtcgagg agcggctcgg gccggccggc gtggtcgccg
    43921 ccaacgcggg catcgccgtc ggcggcccgt tcgccgacac cgccgccgac ctgtggcagc
    43981 gggtcatcga cgtcaacctc accgggtccg ccaacaccgc ccgcgccttc ctgccccacc
    44041 tgacccgcac gcgcggctac ttcctccagg tcgcctcgac cgccgcgctg ggctcggcgc
    44101 ccatgatgag cgcctactgc gcctccaagg cgggcgtgga gtcgttcgca caggcgctgc
    44161 ggggcgaggt cgagccggac ggggtcgccg tcgggatcgc ctacgtccac tggaccggca
    44221 ccgacatgat cagcggcatc gacgaccacc ccgtcctgcg ggccctgcgc cgccaccagc
    44281 cgggcttcgc ccgccgcgtc cgcacccccg agcaggtcgc cgcctggctc gccgagggga
    44341 tcgcccgccg ctccccgtcg gtgtacgcgc cgccctggct gcgctggtgc cagccgctgc
    44401 ggccgctgtt tccggcggtg gtcgcccgca tcgcccgccg cgaactgcgc acccgtacgc
    44461 gcgccgaact ggccgcggac gtcggtgtgc tgggcgacgg cggcctcgcg gactggcacg
    44521 cccaccggca cccggggcac cgggacggct gaccccgccc gcagacacgg gtgcccgggc
    44581 aggcgtcagg cgtcaggcgg ctgccgggcg gtccgcgggc gggcgcctgc gcgccgcggt
    44641 gtcggtcagc gacggcggct gccagacgcc gtcggcccgg tagaggtcgg tgccgggcgc
    44701 cacgatcgcg tcgatgcggt cgagggccgc gtcgtcgagc agcaggtcgg cccccttgag
    44761 cagggaggtc agctggtcca tggtgcgcgg gccgatgatc accgaggtga cggccgggtg
    44821 gacgagcggg aacgcgacgg ccagctccgg gagggtgcag ccgatctccc cggccagggc
    44881 gacgagttcc tcgaccgcct cgaacttggc ggcgttgccc gggagggcgg ggtcgaagcg
    44941 gtgcggggtg cgcgcggccc ggccggtggt gaggtccacg ggccggccct gccggacggc
    45001 cccggagagg aacccggacg cgagcggcga ccacgtcagg acgcccatgc cgaggcgctg
    45061 cgcggtcggc agcacggccc gctcgacgcc gcgcgcgagg atcgagtacg ggggctgctc
    45121 ggtgcgcatc cgcatcagcc cgcgccgctc ggcgacatgg tgggcctcga cgaggtcctc
    45181 cgcggggaac gcggagcagc cgaacgcccg gatcctgccg gccgtcacca ggtcgccgag
    45241 gacggacagc gtctcctcga tgtcggtggt gtggtcgggg cggtgcacct ggtagaggtc
    45301 gatccagtcg gtgtccaggc gccggagact gtcctcgacg gccttcagga tccagcggcg
    45361 ggagttcccg ctgcggttgc ggccctcgcc gagcgggaag tgcaccttcg tggcgaggac
    45421 gacgtcgtcg cgccttccct tgagggcctt gccgacgatc tcctcgctct cgccggccga
    45481 gtacatgtcg gcggtgtcga cgaagttgac gcctgcgtcg agggcggtgt ggatgatgcg
    45541 ggcggcgtct tcgtggtcgg ggttgccgac gcccccgaac atcatcgtgc cgaggcagtg
    45601 ggtgctgacc tcgatgccgg tcttgccgag gacgcggtag cgcatgccgg tgctccgtcg
    45661 caggtggggg tgggtggaag cggcgccagt ctaggacttg gagcacactc gacggcaagg
    45721 tccgcgggcc ggacccccgc cgccggcctg gcggaggacg cggcgcgcgc ggggcacgaa
    45781 ccggccgtcg cagggcggca gatggccgag ggcctggaac gggcctgatc ccggcccggt
    45841 gtcccggtcg gcgctgtcac acccgtgcgg caggctgcct gtcatgagtg accatcaccc
    45901 cggcgcaatg ccgtccccgg accggccacg ggccgggacc gcctggtgcg ggctgctcgg
    45961 ccggagggtc gccgaggccg tggcggccga tgtcatgtcg gcggcttcgg tcttcgacgg
    46021 agccgacgcg ctgccggagt ccgccgaccg cgggttcgcg gtgcctctcg cggcggaggt
    46081 gtgggttttc gacgactccc tcagccgtgt cctgctggtc cgtcacccgt ggcgcggctg
    46141 ggtggcgccg ggcggtcgcg tcgagcccgg cgagacaccg agggaggcgg cgcggcgtga
    46201 gctgttcgag gagacgggcg tgcgggcgag gctgttggcg gaaccggctg cggccaccgt
    46261 ccgttcctac cgtgcgggcg cgccggcgtg tctggggctg tcgtatgcgg cggtcgtgga
    46321 cggggcggtc ccgctcgtcg ccgaggacgg gcaggccgtg gcgtggacat cgctgcggcg
    46381 gggatggacc gggtggtttc ccgaggacgt ggcgcgggtg cgccggtacg ccgggcggct
    46441 gcgtggcggt gccggggact gaagtgcgcg gacctgcctg catcgggagg cggttcgggg
    46501 gcaggagcgg ggctgtgaag tccgttcggc acatcgtctc gttcccgcgg gtcgccgcgg
    46561 cggccggtgt gccggtccaa ccacctcgcc cgaacgcgga ggagcacccc atgcgcggca
    46621 taggcggctg catcgcactg atcctggtgg gggcgatcct caccttcgca agcgactgga
    46681 agatggaggg cgtcaacctg gacgtcgtcg gactgctcat gatgggcacc ggcattctgg
    46741 gtctggcggt gtacgcgagc gtcctgcggc ggcggcgcgt ctcggcggtc gtgccggtcg
    46801 tcgaggagac ccgggagcgc ccctgaccgc cgccggcctt cggccgtcac cggccggccg
    46861 ggaccggggt gaggcggtag gagtcccccc ggcggacgac gcgcccggcg gtgggcggcg
    46921 cgaagtgcgt tcccagcagc agggtgtcgg tgccggccag tgaggccagg agttcgcgcc
    46981 gggtggcttc ggcgagctcg gggtcgatgt cggcgcacga accgatgccg gggcgggcca
    47041 cctggacggg gtggtggatg cagtcgccgg tgatcaccgc cgtaccgccg cggccggcca
    47101 cctcgacggc cgtgtgtccg ggggtgtggc ccggagtggg caggagtctc acctgcggcg
    47161 tgatgccgac gccccctgcc gggacgtcga cgaggtcgag caggcccgcc tcctccaccg
    47221 ggaccaccga gtcgaggaac atccggcggc gggcttcgtc catggcgtgt ccggcccaga
    47281 actcccgttc cgtgcgggag gcgacgtagc gggcgtgggg gaaggtcggg atccaccttc
    47341 cgttctgctt gcgggtgttc cagccgacgt ggtcggcgtg gaggtgggtg aggaggacca
    47401 ggtcgacggc ttccggcggg tagccggccg cggtgaggcg ctccaggtag ccggtgtcca
    47461 ggtcgtgcca ggcggggttg gcccgctgct tgccgttgcc gatgccggtg tcgacgagga
    47521 cgcgcagccc gcctgcggtg aacgcgaagc tgtggctgtc gaggtgcagg acgcccgcgc
    47581 cgtccgcgaa gtgggggcgc agccagtcct cgccggcgac gacctcaggg gtggcggcag
    47641 gcagcagcca cggcccggtg gcgggcggca ggggcgtttc gtcgatgcgg tggacggtga
    47701 tgtcgtcgcc tacggtccag gccggtccgg tggtggtgct cacggttgtt cgtctcctcg
    47761 gcgcggtgcg ggccctgcaa cggcggtcat ggacgggcct cttgacgcta aacgcaatcc
    47821 gtttgcgttt ggccaccgta cggccttaga gtccaaatgc aaactcttgg cttttgcgtg
    47881 agaggaatcc atgccggaca ccgaccccga accgacggct gcacaggcgg ccttgtgggc
    47941 cgcccgcgcc gggctccccc tgccccccgg ccgccgggcc gccgcagccg cggcggcccg
    48001 ccacatccac tccgtcgtcg tcgtcctgcg ggagctcgac ttcgcggaca ccccgcctgc
    48061 cttcgcctac cgcgcacacc aggaggcccc cgatgcagcc gtgtgaactg agcctcgcgg
    48121 aggcggcgga ggccatccgc acccgccgcc tctcccccgt cgagctgacg gactccgtcc
    48181 tccggcgcct cgaactcacg gagccgcgcc tgaacgcgta cgccgcggtc accgccgagc
    48241 gcgcccgggc cgacgctcgc accgcggcac gcgagatcgc ggccggccgc cgccgcggcc
    48301 cgctgcacgg catcccgatg ggcctgaagg acctcatcga cgtggccggc gtgccgactt
    48361 cggccggctc ccgggtgcgc accggtcacc gcgcccgggc cgacagcacg gtcgccgcac
    48421 gcctggcggc ggcgggcgcc gtcctgctcg gcaagaccca cacccacgag ttcgcgtacg
    48481 gcctcaccac cccgcagacc cggaacgccg tggaccccgg ccggatcgca ggcgggtcca
    48541 gcggcgggtc cgcggtcgcc gtggcggccg gctccgcgac cttcgccgtc ggaaccgaca
    48601 ccggcggctc gatccgggtg cccgccgccc tgaacggcgt cgtcggcctc aagccgacgc
    48661 acggcctcgt cccccgccac ggcgtgacgt ccctgtcctg gtccctcgac cacgtcggcc
    48721 cgatcacccg taccgtccgg gacgccggcc tcgtcctcga cgcgctggca ggccacgacc
    48781 cgcgcgaccc cgcctcgatc gccgcaccgc tcgccgccga ccgccggccg cccgccggca
    48841 ccgggctcgc ggggctgcgg atcggcgtgc cgcgcaccta ctacttcgac cgcgtcgacg
    48901 cggacgtcga ggccgccgtc cggcgggcca tcgacggcct ccgcgggctc ggcgcccgcc
    48961 tcgtcggcgt cgacatcccc atggcccgcc acatccaggc cgtccagtgg agcctgatgg
    49021 tgcccgaggc caccgcgtac cacgaacgca ccctgcgcac cgtgcccgag ctgtaccagg
    49081 acgacgtccg cgtcctgctg gaggccggcg cgctcatgcc ggccggcgac tacctgcgcg
    49141 cgcagcgcgc ccgcaccctc atgcggcggg agtggtcccg cctgctccgg ggcgtccacc
    49201 tcgtcgccgc gcccgccgtc ccgacgaccg cggtgcgggc ggggcaggag tgcgtcacct
    49261 ggtccgacgg caccacggag gccgtctcgg acgcctacgt gcgcctctcc tcccccgcca
    49321 acatcaccgg cttccccgct ctcaccgtgc ccgtcggacg cgacgcctcc ggcctgcccg
    49381 tcggcatgca gctgctgggg cggccgctgg gcgaggaggt actcctgcgc gtcgggcacg
    49441 cgtacgagca ggcccgcgag gccgaccgcc cggcacacgc cgcgtagccc cggcacccgg
    49501 ccgggcaccc cgccggaaaa agccacgcct ttgccttaag gtggtgcgtg tgagcaggca
    49561 gatggtgcgt ccgggcgggc gcagcgcgcg ggtccaggcg tccgtgcacg ccgcggtgcg
    49621 cgaactcacc gccgaggtgg gccgggacgc cctcacggtc ccgctgatcg cccagcgtgc
    49681 cggtgtcacc ccctcgacgg tctaccgccg ctggggcgac ctgcaggagc tgctgtcgga
    49741 cgtggccgtg gagcgcctcc ggcccgacac cgccccggcc gaccacggca cgctggccgc
    49801 cgacctgacg gcctgggcag agcagttcct cgacgagatg tcctcccccg ccggccgcgc
    49861 ctacgtccgc gacgcgctgc tcggcgaccc ggacggcggc aacgccggcc agtgctcggc
    49921 ctacgccgcc gggcacatcg gcgtcatcct cgaacgggcg gccgcccggg gcgagcgggc
    49981 accggacacg gaagcggtca tcgaccgcgt cgtcgcacca ctggtgtacc gcatcctgtt
    50041 ccggccggac ggcctggaca cggcccgcgc ccgcgccctc gtggtctcgc tcctggcccc
    50101 ggcgccccgc tgacgggacg cccacctccc cgccgcgccc ggtggcggtg tcggcccggg
    50161 cgagggccgc ggggacctcg gcggcgagtc cgccggcggc caggagggtg tcgaggcgca
    50221 ggaggtcccg gcggcccggc cccgtgccgg cggcggcgcg gtgtgccgcg gggcggggga
    50281 ggtgccgtcc atcgggtcgc ctttccgttc tccggcggag gaggggtgac gcggatccgg
    50341 cgagtggggt cggggtcagc gggcgtcgcg ctgggcggtc acgatgtcgt tgagggtgcg
    50401 ctcgacaccc atgcggccct gcaccctttc ggcgaaggcg gggaactgcc cggcgatcgc
    50461 gctcagcagc ttcaactcgg ccggggcgac gttgacttcg cacaggttcc gctcgacggc
    50521 gcggacgagg ccgtcgcata cctgcgccgg ggagaccgtg cgcatcccgg ccggcggctt
    50581 ggcgcccgtc gcggcgaaca tgccggcgtc gcggacgaat ccgggctgga cgagggacac
    50641 gccgacgccc gtaccgtgca ggtcctggcg gaaggcgagg gcgaagccgc gcagcccgaa
    50701 cttcgtcgcg ctgtagagcg cggaggacct ggtggccgcc ttgccggaga tggagccgac
    50761 gaacgcgatg tggccgcggc gggcccggac catgcgcggc gcgaggagcc gggcgaggag
    50821 gacgggcgcg tgcaggttca cggcgagggc gcgttccacc tgggccgggg tgtagtcgag
    50881 tacgtcgccg ctggagggga gggcggcgtt cgcgacgagg acgtcgacgt cgccgcactc
    50941 ctcggcgagg cgctccacgt cggcggggtc ggccaggtcg gcgacgacgg cgcgggctgc
    51001 gaaccggtcg gcgacggcct gcagcgcgtc cttcctgcgg ccggtgagca cgagggaggc
    51061 acccctgccg gcgagtgctc cggcgagctc cgtcccgagg ccgccggtgg ctccggtcag
    51121 cagaaccgtc gatccgtcga atcgcatccg tggtcgccct ctccccttgt tcgttcgaac
    51181 gaacgggacc atagagcagc ccgaccgaac gtgtccatgc catcgcgtgg atcggttgcc
    51241 gatgcacccg gcccgcgggg cggtttccgc cggatgcgac catggcgcgc atggagaagg
    51301 cagccgacac ccgccagcgc atcatcgacg ccgtccttcg gatcatcggc gcggagggca
    51361 tcgccgcgct gagcaaccgg cggatcgcga aggaggcgca ggtgtcgctg ggctcggtca
    51421 cctaccactt cacgacccag cacgaactgc tgcgggagag cctgctgcac ttcgtcgccc
    51481 aggagacgca gcacttcacc gagctggccg agaactgcgc ccgcgcagac ggcctggaca
    51541 tcccgggcgc ggccgagatg gtggagacgg tggcgggcgg aaccaccttc gacagcaggc
    51601 acatcgcgcc gttcgagctg tacatccagg cggggcgcga cgagcggctc cgggccgccg
    51661 ccgcggagtg cttcgccgcg tacgactcgc tcgcccgcgg catcctccgg cggctcggcc
    51721 tgccggaccc cgatcgcctg gccggcgcgg tggtggccct ggtcttcggg cagcagctgc
    51781 ggagactggc ca
//
