LOCUS       NZ_CP030862            21119 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces globosus strain LZH-48 chromosome, complete genome.
ACCESSION   NZ_CP030862
VERSION     NZ_CP030862.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces globosus
  ORGANISM  Streptomyces globosus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6863360)
  AUTHORS   Ran,K., Li,Z., Wei,S. and Dong,R.
  TITLE     Draft genome Sequence of streptomyces globosus LZH-48
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6863360)
  AUTHORS   Ran,K., Li,Z., Wei,S. and Dong,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2018) Institute of Biophysics, Dezhou University,
            566 DaXuexi RD, Dezhou, Shandong 253023, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Portal v. version 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003325375.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:22:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,671
            CDSs (total)                      :: 6,576
            Genes (coding)                    :: 6,458
            CDSs (with protein)               :: 6,458
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 41 of 118
            Pseudo Genes (incomplete)         :: 101 of 118
            Pseudo Genes (internal stop)      :: 11 of 118
            Pseudo Genes (multiple problems)  :: 32 of 118
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:39:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3672081
            Orig. end                         :: 3693200
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030862.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21119
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="21"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21119
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21119
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11119](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11119)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            110..>300
                     /locus_tag="C0216_RS34410"
                     /old_locus_tag="C0216_15975"
                     /pseudo=""
     CDS             110..>300
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638990.1"
                     /locus_tag="C0216_RS34410"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="C0216_15975"
                     /product="ArsR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPPATSPFPSRSERPPARGADPVRCRFLPALRAAPAHPADLALRR
                     SASPVPDCRTTWPACATA"
     gene            complement(340..873)
                     /locus_tag="C0216_RS16005"
                     /old_locus_tag="C0216_15980"
     CDS             complement(340..873)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524345.1"
                     /locus_tag="C0216_RS16005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_15980"
                     /product="hypothetical protein"
                     /protein_id="WP_114055939.1"
                     /transl_table=11
                     /translation="MANRSYLYAADTLPTEQENAQAIRCVSQHNWSIPLAHQLLVGRGT
                     AIVPSMIWNPRIGIAADYAGGAALLGDLLRAVGRGLEDDAGFARCVEQTTAHLEKQRAR
                     YFVLETGEMVSLTDDDPEAGVRRLVADDIPAAVARAEEAIAGRDDAWLASIRTDWEEHF
                     DSFYSDVLYFSFPG"
     gene            complement(1100..4318)
                     /locus_tag="C0216_RS16010"
                     /old_locus_tag="C0216_15985"
     CDS             complement(1100..4318)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018101710.1"
                     /locus_tag="C0216_RS16010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_15985"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_246042567.1"
                     /transl_table=11
                     /translation="MGPVRYLILGVTEARSAAGSPLPIGGARLRALLAALALRAGGPAA
                     ASVTDLVDDVWGDRPPRDAPAALQALVARLRRALGGRDTVLADPAGGYRLAVADRDDVD
                     LHRFTRLAREGRARLTAAPADPAGAAARLRSALDLWRGPALADLPEPARSRHAAPLEAR
                     RTTALRDRIEADLRSGAADPAGLSAQIEALIRENPYDETLRAQQLRALRAAGRPAEALA
                     AYERTRRTLADALGADPGPELVALHAELLNPAAAPAGERPGPAGGNLRPRLNSFVGREQ
                     ELAALRDDLAGLRLVTLTGPGGSGKTRLAEEGAAAHPDPVWLVELARLDQPGAVPGAVL
                     SALGLREDTLVAREAPAADPAARLVELCADRRLLIILDNCEHVVGAAAELAELLLTHCP
                     GVRILATSREPLGVPGETLRPVGPLPPGPAHRLFADRAAAALPGFTPDDDPDAVAETCT
                     RLDGLPLAIELAAARLRLLTPRQIADRLDDRFRLLTGGARTVLPRQQTLRAVVDWSWDL
                     LDEAERTVLRRLSVFAGGCDLAAAEAVCGEGSGPDTAGLLGSLVDKSLVVATPDPDSRG
                     MRYRMLETIHEYAAERAAADDADRLAAADRHAAYFLALAEEAEPLLRGSAQLPWIRRVE
                     TELDNLRAALRHTTGAGSAEAGERFAVALGWFWWLRNYRAEGADWVGRILRNRSAEPPE
                     GTPAYWRLMRVRMLDVFLRAQGETPEEFRTPANAALAERMRKVFARPGPETARFPGMLW
                     PMTLLLAGDVLDVRGALDTAVENCRRHGGAWELGVTLLLRTHLALDVTGGLPAVDADLA
                     ELHDLAERVGDRWTRAQVAAAAGEAALSRGRYGAARGEFDECLRLAREVGAHTETPFIT
                     ARIAEAALCAGDFAGAERLLAESAREVDRYGGVYDVRAYAGLLSSLVALIRGDLAAARA
                     VHGRARADAARFAAPAQLIAGLDNIDAVLRGREAGPEAGLAAIGPALAGAVAAHCAERV
                     LASLADTAAALLSRAGRTGEAVRVLGAATAWRAGHPRSVLEQAAVAAIPDEARALLGPD
                     RYGKEAAEGAALTPAEVAALLTTG"
     gene            complement(4501..6099)
                     /locus_tag="C0216_RS16015"
                     /old_locus_tag="C0216_15990"
     CDS             complement(4501..6099)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019604.4"
                     /locus_tag="C0216_RS16015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_15990"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_114055940.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.6e-32, bitscore:
                     109.4, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 1.2e-07, bitscore: 30.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADAALPVIVLSDPDPLRRHDTAELVQSWYRTSFRVLQVGGPAEV
                     VRALDSLADRRVPVAAVLADEAPAPGDARHPGVRWLPLARHRDAAPAAADITPAPGSRT
                     EDLRGALDDSLCTWNADARGELPTAEVRGSRFSPAAYAVRDFLGRSGVIFRWLPEQEAR
                     DAPVTVRLGDGTEMADPSISELAERLGLIRPAGQDHYDVAVIGGGPGGLSAAVYAAAEG
                     MSVVVIEDDAPGGQAGTTSRIENYLGFPTGLTGGDLAQRALQQARRARVEWQPTRVASR
                     VSPAEDGRHRIDFVKAGTDETASVTAAAVVVATGVDWNRLTAPGVDRLLNSGVYYGSCL
                     SDAPSAAGEDVYMVGAGNSAGQAALYFARYARTVTLLVRGTDLGASMSDYLVRRIGRTP
                     GLRVLLGTEVAECLGETTLTGLRLRERDGREQTVTAHCLYVLIGGHPSTDWLGGALALD
                     DRGYVLTGSGAAGGDALPMETSVPGVFAVGDVRAGSVKRVGAAVGEGAAVAQCLVEYRR
                     RHPTLFPDARAVCGF"
     gene            complement(6301..6840)
                     /locus_tag="C0216_RS35020"
                     /old_locus_tag="C0216_15995"
     CDS             complement(6301..6840)
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024890.4"
                     /locus_tag="C0216_RS35020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_15995"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_162793230.1"
                     /transl_table=11
                     /translation="MSVLDMKLDRSFDVFDADRDGRLRKSDVTGLSDKLAESLGVAPDA
                     VAGLRGSLEDLWDAVFQKMDRDGDGGVDRLEFRAAFRARIVTDQNRIWDRIRSMSNAWT
                     ELGDRDGDGMLSREEYTDLLHGMFRLPRETFEEAFNGLDSDGDGQLSRDEISRAMKEYY
                     TSEDHTARGNHFFGRL"
     misc_feature    6816..6830
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 15.82"
                     /tool="antismash"
     gene            complement(6997..8547)
                     /locus_tag="C0216_RS16025"
                     /old_locus_tag="C0216_16000"
     CDS             complement(6997..8547)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122765.1"
                     /locus_tag="C0216_RS16025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16000"
                     /product="DUF4246 domain-containing protein"
                     /protein_id="WP_342777109.1"
                     /transl_table=11
                     /translation="MVPVVAHPSERPRQLTGKSAFPLPFESVRSALFATPRTLREVEMM
                     QCSAHIRAKQGWFDKKDDPEVVARWTREAVAQGLTEAQVAYVLAELAHYARLRDAGTGI
                     EVSAVDGVWQSDTLVDDGLRSRLREAVRVLEEVPEEQKDWHPGSGGQVLDLVHPSLFCL
                     VREVSGGPERAWRNPTASYSKHEFSEKFQWLPSDVDVSDDGQVVFRSYVNNVHPEEHRE
                     LAAVLPDLFARMLPLLENVLTDLRHPRPLRIEADPYDWYDSEPERPDRAAFDDDQAYQA
                     ALHAWGKAQDDWWQNRRPVVPDAPEFTPPELPGASSRVDLRGRRLQVIVKLATVHLTPE
                     QPEYPGGSWHVEGMLNERIVSTGIYYWDSENITESRLGFRAALDDPYYEQNDGNGVREV
                     YGLEDEDALNQVLGSVPTPAGRCLAFPNVLQHRVDAFRLADPARPGHRKILAFFLVDPS
                     ETIVSTSDVPPQQPWAGTATMTLEQAKQYREELMQERKFFVAEHNEQVYEREFSLCEH"
     misc_feature    8519..8534
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.26"
                     /tool="antismash"
     gene            complement(8631..9986)
                     /locus_tag="C0216_RS16030"
                     /old_locus_tag="C0216_16005"
     CDS             complement(8631..9986)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018847667.1"
                     /locus_tag="C0216_RS16030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16005"
                     /product="cytochrome P450"
                     /protein_id="WP_246042568.1"
                     /sec_met_domain="p450 (E-value: 1.4e-82, bitscore: 276.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQGLESIPPAPGRVPLLGHALKLGRDPLAFLRSLRDVGDLVRVD
                     LGSMPMYVVTSAALVRDVTVGQARAFEKGRLYDRVRPLVGNGLATAGGDVHRRHRRLIQ
                     PMFHQTCIAGYAETMSSRARALADSWTPGQTIAVEQVMGELAVEILAATMFSTDIGRPA
                     VEAVRRDLPVILKNMLLRAASPKALDHLPIPPNRAFDAAARSMRQVIDDVIAGTRRSGE
                     GHQGGGDLLSVLLDARDADTGEALTDEEVRDELVTILFAGTETTASTLSWAFHEIARHP
                     EVEKQLVAEVDEVLEGRPATIADVPRLVGIRRVLDEVIRLHGVTLLMRRTTEEVELGGF
                     RLPAGTEVAFSLYALHRDPALYADPDRFDPDRWLPERRGDIPREAFVPFGSGNRRCIGD
                     AFAWTEATIVLATVLSRWQLRPCPGHSPREAASAMAHPDHVPMEVHPRGTAR"
     gene            complement(10001..11119)
                     /locus_tag="C0216_RS16035"
                     /old_locus_tag="C0216_16010"
     CDS             complement(10001..11119)
                     /EC_number="4.2.3.181"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005317515.1"
                     /locus_tag="C0216_RS16035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16010"
                     /product="selina-4(15),7(11)-diene synthase"
                     /protein_id="WP_114055944.1"
                     /sec_met_domain="T1TS (E-value: 6.6e-79, bitscore: 264.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNEPGLIVPPIYTPIPPAIHPRYQAVEAHTAAWAEAFQVGSDEL
                     RTRLLRHSIGTFAARILPAGQEPVVALLSDFVLWLFAVDDGFCEEGALGRRPGDLAGVL
                     HRLLRVAQNPEAPMLLDDSLADGLRDLTRRVSRHGTAGQAAAWCNALREYFFSVVWEAS
                     HRREGTVPSLADYTLMRLYDGATTVVYPLLEMGHGYELPMHERDQPYVRAATEMASFVI
                     TWDNDLFSHHKESRGDGYYLNAIRVLQEERGLTPDQALATAIEQRDRVMCLFMRLQESL
                     ADQASPQLRTYFQGLGSFIRGSQDWGVSSHRYTTPEDPASLPTSFRQTPVVDDGEPLEI
                     PAVSWWWNLLPDPQRRVPSARMPMPALLAPTP"
     misc_feature    11112..11127
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 15.87"
                     /tool="antismash"
     gene            complement(11388..12806)
                     /locus_tag="C0216_RS16040"
                     /old_locus_tag="C0216_16015"
     CDS             complement(11388..12806)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735524.1"
                     /locus_tag="C0216_RS16040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16015"
                     /product="cytochrome P450"
                     /protein_id="WP_246042569.1"
                     /transl_table=11
                     /translation="MSTLRPEHPGHGHGAVPPPGCPAHVQGGSGIARLYGPEALADPSA
                     FYEALRARHGAVAPVLLHGDLPAWLVLGHRENLEVMRKPTLFSRDSRRWTAFQEGRVSP
                     DSPLGPTVGWQPICVFADGAEHERLRGAVTDSLAQVDRRGIRRYVVRHTKQLVDAFALS
                     GQADLVAQYAEKLPMLVMCQLLGMPDRYGPHLVSACLDLMKGSQTALASNDFLVDTLRE
                     LVQQKKGAPGRDFASWLIGHASNLTDDEVLEHLRLVLVAANETTVNLIANTLRMVLTDP
                     RFRASLAGGHMTLPDALEQVLWDAPPLSVVPGRWATGDTVLGDQPIRQGDMLLLGLAAG
                     NVDPDIRSDLSLPVHGNRSHLAFSSGPHECPGRDIGRAIAEAGIDTLLSELPGLELRAA
                     ADELSLTTSWVSTRVNSLPVRFPPRRVTPAPTAQPDAAAHPPVSAFTAGARQHGQHHTA
                     TARRPWWKSLLKLR"
     misc_feature    complement(12911..12924)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.74"
                     /tool="antismash"
     gene            complement(13022..13609)
                     /locus_tag="C0216_RS16045"
                     /old_locus_tag="C0216_16020"
     CDS             complement(13022..13609)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437480.1"
                     /locus_tag="C0216_RS16045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16020"
                     /product="cysteine hydrolase family protein"
                     /protein_id="WP_114055945.1"
                     /transl_table=11
                     /translation="MEITENTALVVVDVQKGFDDAAYWGPRNNPAADGNIASLITAWKD
                     TGRPVVFVRHDSVSPGSPLRAGSAGNAFKDYVEARRGSGAGLELLVTKSVNSAFYGTPD
                     LDAWLREAGITRIVLAGIQTNMCVETTARMAGNLGYDVLFALDATHTFDLTGPDGRPVT
                     ADDLARATAASLHGGGFARVVDTAALTAAART"
     gene            13683..14696
                     /locus_tag="C0216_RS16050"
                     /old_locus_tag="C0216_16025"
     CDS             13683..14696
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453288.1"
                     /locus_tag="C0216_RS16050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16025"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_114055946.1"
                     /transl_table=11
                     /translation="MNRPAPAHRIALLAFPGIRAFDVSVVTEVWGVDRTDRGVPAFELR
                     RVAAGPDPVPMRGGLALTPDRTLAWLPRARLVLVPGLDEHAEPAPEPVLAALRRAHARG
                     TAIAALCGGAFTLAQAGLLDGRRALTHWALADLLRARHPRVRVGPDALFVEDGNVWTSA
                     GTAAGIDLCLHLVRTAHGAEAAAAIARSMVTAPFRTGGQAQFIERPTPRTDRGADALAG
                     VRAYALAHLDEPLGVAALAARAGMSPRSFARNFAAATGTTPLRWLLEHRIAAAQKLLER
                     TDLPVPEVARRAGFGSEVTMRQHFASRLGTSPRAYRASFAGEGSNQEPNSGFAGSS"
     gene            14754..15536
                     /locus_tag="C0216_RS16055"
                     /old_locus_tag="C0216_16030"
     CDS             14754..15536
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013702.4"
                     /locus_tag="C0216_RS16055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16030"
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_114055947.1"
                     /transl_table=11
                     /translation="MSESIIGVVDIAKSELRFLRHMLGDAGENAWERLLEWFIDDWFRL
                     DVLGLENVPAEGPAVLVANHSGAWGLDAFVMQKALVRSLRRPLQVLAAPFVFHLPVLGP
                     YAARKGAVPIDLRAGMQHLAGGGLITVFPEGVSGLEKPFRERYRLQPFNPGFAVAALHT
                     GAPIVPVAVIGAEESSPRMGELPALAKFLGLPSFPLTSFFPLPAKWLITIGEPVAPPER
                     PRGAGARSAAARRLAGEVQAVVQDMVVRERGRRDTLVR"
     misc_feature    complement(14755..14769)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.72"
                     /tool="antismash"
     gene            complement(15603..17084)
                     /locus_tag="C0216_RS16060"
                     /old_locus_tag="C0216_16035"
     CDS             complement(15603..17084)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS16060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C0216_16035"
                     /product="hypothetical protein"
                     /protein_id="WP_114055948.1"
                     /transl_table=11
                     /translation="MTTPAAALPLENAVFSAALLARRLPWSDAPARALGLDSLTCEGAA
                     RGVLAHLRRSRSGRPVRLRTPLGSFLVPLKPADTAGLLAAGAAADALAPAVRLDEAGRR
                     HGLHPHHPLPLPAPPEDVLPEAALAGPLAGELRRLASARRDDQALTWEAWRPGLLRAAR
                     RVVAGAAAAEDTLLGEMLRRAAEAAGSHAYESRAAAVHRRLAPYLADPDPDSLAAVLAR
                     PAAGPAVPAARAEHGPPAGAGRPEEALAHALAVVSEAAATTALQALALTAAGVPAAAGG
                     PAAAVALALDRFPPVGAAVHPVRSRFSWEGLAVDAGTEILAAPGWLRSATDHAGGAGAE
                     PGPLPGGGPSPLCGSPTGCAAAAVAVRVAEAVVRFFTEDAEGARPALLAPALSPDRMPL
                     TLDPRTLLLAFPAAGAPAAAPPARAGTPASYAAPARAAAGRLDRHARSLAACAADAGWD
                     GSETGERFRMRLLEHADRCTRAASDIREAARRLAD"
     gene            complement(17268..18767)
                     /locus_tag="C0216_RS35025"
                     /old_locus_tag="C0216_16040"
     CDS             complement(17268..18767)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013890.4"
                     /locus_tag="C0216_RS35025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16040"
                     /product="lipase family protein"
                     /protein_id="WP_114055949.1"
                     /transl_table=11
                     /translation="MTPQATGASPRHLTDGRRKDIPDAGPLPGPCDTPALPDAGPAGSP
                     EATAAATPADGDLLIAASVLLADAALAARQAGAHLTAALTGGSFALQALRRPAWAAGAT
                     LSCLRALTSRAGLGFAANGGTVGELARIAGNLTRRRPASVAMAVDAFALRIEAATAAHP
                     NLDSPHARRLTDALVAGDRLEAARALHALVERLGVTRALTTISPVIMELLALLGLLDEN
                     PVNDSFSWVTLAGGVPTTDPLFGLPCSLIKHLNPGPGRAERADPDPILAKVLGTSRNDI
                     VSYINDIGALGNHGLVLLRRIACTDGAVRHVLLLPGTSFALLSNSTPQDLVGAFDGCLR
                     TDTTYTRAARKLLKRAGVPAGSELMMVGHSLGGLTAMNLAADLDTASEYRITHVVTLGS
                     PIDNKRPADHTTRVVSLVNKHDVIPMLDGRGPASPHDVPDSWVELSWLDESYDYPLSHA
                     PQAYSDSLRGELAHHRDRVNALIGSYDGEIIGNQPYMLRDR"
     gene            19029..20117
                     /locus_tag="C0216_RS33515"
     CDS             19029..20117
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS33515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162793231.1"
                     /transl_table=11
                     /translation="MSTAGNELIDVVPLGTVRARGTVEAVAGGRLLVRAGGLLEVHDRE
                     EFLAGTAAGPVASLRVEEQERAAAASDGGFLVAGAASVRAVGPDGGTRWEFAHDPWHGT
                     PRARSAPAPSPDGRLVGVVVPTQEPDPARAALVYDAEPGRSYVWDRLLFLDAASGEVVG
                     RQQLRSLASGVVLGWRPDGGALAVSCWTAWHSWSTWWAEPTGSADADDGIRIAGGTWMH
                     ALAGFLPGSRTLTQRYAEHVWPDDDRDELAVYDTGSGGQVAVLDLAALAPDPAEDEFRS
                     AGVLDGRHVLVPGRVFRAGGPPQARHWLIDAASLRPLGRLAYPAAVGRDVTVLGDGTWL
                     TEDDGGRLHRWALGRTERAASG"
     gene            20232..20381
                     /locus_tag="C0216_RS33520"
     CDS             20232..20381
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS33520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162793232.1"
                     /transl_table=11
                     /translation="MITSVDTGFSLAEAPPEPAEALAAQAARCLGAVRAAPAAREEAAL
                     RAGR"
     misc_feature    20235..20249
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.36"
                     /tool="antismash"
     gene            complement(20365..>20544)
                     /locus_tag="C0216_RS16075"
                     /old_locus_tag="C0216_16050"
                     /pseudo=""
     CDS             complement(20365..>20544)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991713.1"
                     /locus_tag="C0216_RS16075"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16050"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="QRIRRDRALPETTDDVIAAATGTGTATTLRRHFRRTVRVPPDTYR
                     RTFRLRRPDLTSRP"
     gene            complement(20751..21071)
                     /locus_tag="C0216_RS16080"
                     /old_locus_tag="C0216_16055"
     CDS             complement(20751..21071)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010468039.1"
                     /locus_tag="C0216_RS16080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_16055"
                     /product="hypothetical protein"
                     /protein_id="WP_114055950.1"
                     /transl_table=11
                     /translation="MASTTWTTTGVFTGPGGVRTAEAGTLAGELAVRTVWEPQQAHVCV
                     QYVGDTEWYPLAGSPVPCPTPEVGRTVHQGAVDAVRAGGAVPFTLPPAVRAAYGTPTQA
                     GG"
     misc_feature    21066..21076
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
ORIGIN
        1 ctgtccgcgt acgacgcggt gtacgcgtgg gcggccgccc gcggccgggc cccggcgggc
       61 tcgcctcgtg aggtctactt cgcggactgg gcggcgatcg gcgcggccga tcccgcctgc
      121 gacatcgccc ttcccctcgc ggagtgagcg gccgccggcc cgcggcgccg acccggtccg
      181 ctgccgcttc ctgcccgccc tgcgggctgc gcccgcccac ccggcggacc tcgccctgag
      241 gcgatcggcg tcccccgtac ccgactgccg gaccacctgg cctgcctgcg cgaccgcggc
      301 ccggccgccg tggcaccgga cggccggtgg accgggtggt cagccgggga aggagaagta
      361 gaggacgtcg ctgtagaagg agtcgaagtg ctcctcccag tccgtgcgga tcgaggccag
      421 ccatgcgtcg tcgcggccgg cgatcgcctc ctccgcccgg gccacggcgg cggggatgtc
      481 gtcggcgaca aggcgtcgga ctcccgcctc ggggtcgtcg tccgtgaggg agaccatctc
      541 gccggtctcc aggacgaaat accgcgcccg ctgcttctcc aggtgggccg tggtctgctc
      601 gacgcaccgg gcgaagccgg cgtcgtcctc caggccgcgg ccgaccgcgc gcaggaggtc
      661 gccgagcagg gcggcgccac cggcgtagtc cgccgcgatg cctatgcggg ggttccagat
      721 catggacggg acgatggccg tcccgcgccc gaccaggagc tggtgggcga gcggaatcga
      781 ccagttgtgt tgcgagacgc agcggatcgc ctgggcgttc tcctgctcgg tgggcagggt
      841 gtcggcggcg tagaggtatg agcggttggc catgtgggcg accgtaacag cggggtccga
      901 cagtgccggc cggagaaggg ggcgccctgg gcggagctgc gggctgacgt actgccggcc
      961 cgccgccccg ctcgctgtgt gggcggcggt cctggccgcc ctggcgatct gaccccgcag
     1021 cgaggacggc acggcctgat gcttcggggg cgggggcggg ggcggggccg agaccggggc
     1081 aggggcgggc gcggccggct cagccggtgg tgagcagggc cgcgacctcg gccggggtga
     1141 gcgcggcgcc ctccgccgcc tccttcccgt agcggtccgg gccgagcagg gcgcgggcct
     1201 cgtccgggat cgccgcgacg gcggcctgct ccagcacgga gcgcgggtgc cccgcgcgcc
     1261 acgccgtggc cgcgccgagg acccgcacgg cctccccggt gcgtcccgcc cgcgacagca
     1321 gcgctgccgc ggtgtcggcg agcgaggcca ggacgcgctc cgcgcagtgc gcggcgacgg
     1381 cgccggccag cgccggcccg atggcggcga ggcccgcctc cgggccggct tcacgccccc
     1441 gcagcacggc gtcgatgttg tcgaggccgg cgatgagctg ggcaggagcc gcaaaccggg
     1501 cggcatccgc gcgggcccgc ccgtgcacgg ctcgggccgc cgcgaggtct ccgcggatga
     1561 gggcgacgag gctcgacagc agtccggcgt aggcgcggac gtcgtacacg ccgccgtacc
     1621 ggtcgacctc gcgggccgac tcggccagga gccgctccgc gccggcgaaa tcccctgcgc
     1681 agagtgcggc ttcggcgatg cgggccgtga tgaacggcgt ctccgtgtgg gcccccacct
     1741 cgcgggcgag gcgcaggcat tcgtcgaact cgccgcgcgc cgcaccgtac cggccccggg
     1801 agagcgccgc ctcgccggcg gcggccgcca cctgggcgcg ggtccaccgg tcgcccaccc
     1861 gttcggcgag gtcgtggagt tcggcgaggt cggcgtcgac ggcgggcagg ccgccggtga
     1921 cgtcgagggc gaggtgggtg cgcagcagga gggtgacgcc cagctcccag gccccgccgt
     1981 ggcggcggca gttctcgacc gccgtgtcga gggctccgcg gacgtcgagg acgtctccgg
     2041 cgaggaggag ggtcatgggc cagagcatcc cggggaagcg ggccgtctcg ggcccgggcc
     2101 tcgcgaacac cttccgcatg cgctcggcga gcgcggcgtt ggcgggggtg cggaactcct
     2161 cgggcgtctc gccctgggcg cgcaggaaga cgtcgagcat gcggacgcgc atcaggcgcc
     2221 agtaggcggg ggtgccctcg ggcggctcgg cggaccggtt ccgcaggatg cggcccaccc
     2281 agtcggcgcc ctcggcgcgg tagttgcgca gccaccagaa ccagccgagt gcgacggcga
     2341 aacgctcccc ggcttcggcc gatccggccc cggtggtgtg ccgcagggcc gcccggaggt
     2401 tgtccagctc ggtctcgacg cgccggatcc acggcagctg ggcggagccg cgcagcagcg
     2461 gctcggcctc ctcggcgagg gccaggaagt acgcggcgtg ccggtcggcg gccgcgaggc
     2521 ggtcggcgtc gtccgcggcg gcgcgttcgg cggcgtactc gtggatcgtc tccagcatcc
     2581 ggtagcgcat gccgcggctg tcggggtcgg gggtggccac gacgagggac ttgtcgacga
     2641 gcgagccgag gaggccggcg gtgtccgggc cgctgccttc accgcagacg gcctcggcag
     2701 ccgccaggtc gcagccgccg gcgaagacgg agagcctgcg caggacggtc cgctccgcct
     2761 cgtcgaggag gtcccacgac cagtcgacga cggcgcgcag ggtctgctgg cgcggcagga
     2821 ccgtacgggc tccgccggtc aggagccgga agcggtcgtc gaggcggtcg gcgatctggc
     2881 gcggggtgag cagcctcagc cgggcggcgg ccagttcgat ggccagcgga aggccgtcga
     2941 ggcgggtgca cgtctcggcg acggcatcag ggtcgtcgtc cggggtgaag ccgggcaggg
     3001 ccgcggcggc gcggtcggcg aagaggcggt gcgcgggccc cggcgggagc ggcccgacgg
     3061 ggcggagtgt ctcgccgggc acgccgaggg gttcgcggct cgtcgcgagg atccggacgc
     3121 cggggcagtg ggtgaggagg agttcggcaa gttcggcggc ggcgccgacg acgtgctcgc
     3181 agttgtcgag gatgatcagc aggcggcggt cggcgcacag ttcgacgagc cgcgcggcgg
     3241 ggtcggccgc gggtgcctcg cgggccacga gggtgtcctc gcgcaggccg agggcgctga
     3301 ggacggcgcc gggaacggcg ccgggctggt cgaggcgggc gagttcgacc agccacaccg
     3361 ggtccgggtg ggcggcggcg ccttcctcgg cgagccgggt cttgccggag ccgcccggcc
     3421 ccgtgagggt gacgaggcgc aggccggcga ggtcgtcccg gagggcggcc agttcctgtt
     3481 cgcgtccgac gaaggagttc aggcgcggcc gcaggttgcc gcccgcgggc ccggggcgct
     3541 cgcccgcggg cgcggcggcg gggttcagca gttcggcgtg cagggcgacg agttcggggc
     3601 ccgggtcggc gccgagggcg tctgcgaggg tgcggcgggt gcgctcgtac gcggcgaggg
     3661 cctcggcggg ccggccggcc gcccgcaggg cccgcagctg ctgggcgcgc agcgtctcgt
     3721 cgtacgggtt ctcccggatc agcgcctcga tctgggccga cagccccgcc gggtccgcgg
     3781 cgccggagcg caggtcggcc tcgatgcggt cgcgcagggc ggtggtgcgc cgtgcttcga
     3841 ggggggcggc gtgccggctg cgggcgggtt cggggaggtc ggcgagggcc gggccgcgcc
     3901 acaggtcgag ggcggagcgc aggcgggcgg cggcgccggc gggatcggcg ggggccgcgg
     3961 tcagccgggc gcggccttcg cgggcgaggc gggtgaagcg gtgcaggtcg acgtcgtcgc
     4021 ggtcggcgac ggcgaggcgg tagccgccgg cagggtcggc gaggacggtg tcccgtccgc
     4081 cgagcgcccg gcgcaggcgg gcgacgagcg cctggagggc ggccggggcg tcccggggag
     4141 gccggtcgcc ccagacgtcg tcgacgaggt cggtgacgga ggcggcggcc gggccgccgg
     4201 cgcgcagggc gagggcggcc aggagcgcgc gcaggcgcgc cccgcctatc ggaagggggg
     4261 agccggccgc gctgcgcgct tcggtgacgc cgaggatgag gtaacgcacc gggcccattg
     4321 tgccggaccc ccggcgggcc gccgcggcgc cccggcccgg gtgcgcggcc ccccgccatc
     4381 gggccgtgca cggggtgtcg gccaggcccg cggagtccgg cgccgtgccg cgcacgggcg
     4441 tacgccggcg ggtccggcag cggcgggtcg cgacaccggg ggcgccggcc cgagtccccg
     4501 tcagaagccg cagacggcgc gggcgtccgg gaagagggtg gggtggcggc gccggtactc
     4561 gaccaggcac tgggcgaccg cggcgccctc ccccacggcg gcgccgaccc gcttgaccga
     4621 tccggcgcgc acgtcgccga cggcgaacac gccggggacg ctggtctcca tcggcagcgc
     4681 gtccccgccg gccgctccgc ttccggtgag gacgtagccg cggtcgtcga gggcgagcgc
     4741 cccgccgagc cagtcggtcg aggggtggcc gccgatcagg acgtacaggc agtgtgcggt
     4801 gacggtctgc tccctgccgt cgcgctcgcg caggcggagg ccggtgaggg tggtctcgcc
     4861 gaggcattcc gcgacctcgg tgccgaggag gacgcgcagg ccgggggtgc gcccgatgcg
     4921 ccggaccagg tagtcggaca tggaggcgcc gaggtcggtg ccccgtacga ggagggtgac
     4981 ggtgcgggcg tagcgggcga agtagagggc ggcctggccg gcggagttgc cggcgccgac
     5041 catgtagacg tcctcgccgg cggccgaggg cgcgtcggag aggcacgagc cgtagtagac
     5101 gccggagttg agcaggcggt cgacgccggg ggccgtcagg cggttccagt ccacgccggt
     5161 ggcgacgacc accgcggcgg cggtcacgga ggcagtctcg tcggtgcccg ccttgacgaa
     5221 gtcgatccgg tggcggccgt cctccgcggg cgagacccgg ctggcgacgc gcgtgggctg
     5281 ccattcgacg cgggcgcggc gggcctgctg cagggcgcgc tgggcgaggt cgccgccggt
     5341 gaggccggtc gggaagccga ggtagttctc gatccgcgag gtcgtccccg cctgcccgcc
     5401 gggcgcgtcg tcctcgatga cgacgacgct catgccctcg gcggccgcgt acaccgccgc
     5461 ggacaggcct ccgggaccgc cgccgatcac ggcgacgtcg tagtggtcct gcccggcggg
     5521 gcggatcagg ccgagccgtt cggcgagttc gctgatcgac gggtccgcca tctcggtgcc
     5581 gtcgccgagg cggacggtca ccggcgcgtc ccgcgcctcc tgctcgggca gccagcggaa
     5641 gatgacgccg ctgcggccga ggaagtcgcg caccgcgtag gcggcgggcg agaagcggct
     5701 tccgcgcacc tcggcggtgg gcagttcgcc gcgggcgtcg gcgttccagg tgcacaggga
     5761 gtcgtcgagc gcgccgcgca ggtcctcggt gcggctcccg ggggccgggg tgatgtccgc
     5821 ggcggcgggg gcggcgtcgc ggtggcgggc cagcggcagc cagcggactc cgggatgccg
     5881 ggcgtcaccg ggggccgggg cctcgtcggc gaggacggcc gcgacgggta cccggcggtc
     5941 cgccagcgag tccagcgccc ggaccacctc tgccggcccg ccgacctgga gcacccggaa
     6001 ggaggtccgg taccagctct gcaccagctc ggccgtgtcg tggcggcgga gcgggtcggg
     6061 gtcggagagg acaatcaccg gcagtgcggc atcggccatc aagggatcct ccaaggggag
     6121 cggggtggga tgatcggctt ccgctggggg tcaacgagcg ggcgggcgat acgaagcggc
     6181 ctcggtccgg ccggagcgcg gcggggcggg gcgggtgcgg ggccgtcggg acgtcgggcc
     6241 ttcgcccccg ccacgccccg ccccgcgctg gaccggtcgg gatcgctgga ccggtcggga
     6301 tcagaggcgg ccgaagaagt ggttgccgcg ggcggtgtgg tcctcgctgg tgtagtactc
     6361 cttcatcgcg cggctgatct cgtcacggct caactggccg tcgccgtcgg agtcgagccc
     6421 gttgaacgcc tcctcgaagg tctcgcgggg caggcggaac atgccgtgga ggaggtcggt
     6481 gtactcctcg cggctgagca tgccgtcgcc gtcgcggtcg ccgagctcgg tccaggcgtt
     6541 gctcatgctc ctgatgcggt cccagatccg gttctggtcg gtgacgatgc gcgcccggaa
     6601 cgccgcccgg aactccaggc ggtcgacgcc gccgtcgccg tcgcggtcca tcttctggaa
     6661 gacggcgtcc cagaggtcct ccagcgagcc gcggagtccg gcgacggcgt cgggggcgac
     6721 gccgagcgac tcggcgagct tgtccgagag gccggtcacg tccgacttgc ggagccgtcc
     6781 gtcgcggtcc gcgtcgaaga cgtcgaagga ccggtcgagc ttcatgtcca gcacgctcac
     6841 agcaggcatc cccttcactc ggttcggtcc gccgaatcta gtccggtgaa gggggaagcc
     6901 atgaccgtga tcacccgttt ggagcgcagc acacccgtac gggcgacgtt ctcccgttca
     6961 aacccgtacg tccgcgacgg gcacgcgctc gggccgtcag tgctcgcaga gggagaattc
     7021 ccgttcgtag acctgctcgt tgtgctcggc gacgaagaac ttgcgttcct gcatgagttc
     7081 ctcgcggtac tgcttcgcct gctccagcgt catggtcgcg gtgccggccc acggctgctg
     7141 cgggggcacg tcggaggtcg agacgatcgt ctccgacggg tcgacgagga agaacgcaag
     7201 gatcttgcgg tgcccggggc gggcggggtc cgcgagccgg aacgcgtcga cgcggtgctg
     7261 caggacgttc gggaacgcca ggcagcggcc cgccggggtc ggcaccgatc ccagcacctg
     7321 gttcagcgcg tcctcgtcct ccaggccgta gacctcgcgc accccgttgc cgtcgttctg
     7381 ctcgtagtac gggtcgtcga gtgccgcgcg gaagcccagg cggctttcgg tgatgttctc
     7441 gctgtcccag tagtagatgc cggtcgagac gatccgctcg ttcagcatcc cctcgacgtg
     7501 ccaggagccg cccgggtact cgggctgctc cggggtgagg tggaccgtgg cgagcttgac
     7561 gatgacctgg agccggcggc cgcgcaggtc gacccgggag gaggcgccgg gcagctcggg
     7621 cggggtgaac tccggggcgt ccgggacgac cggcctgcgg ttctgccacc agtcgtcctg
     7681 ggccttcccc cacgcgtgga gtgccgcctg gtaggcctgg tcgtcgtcga acgcagccct
     7741 gtccgggcgt tccggttccg agtcgtacca gtcgtagggg tccgcctcga tccgcagggg
     7801 ccgcgggtgc cgcagatcgg tgaggacgtt ctccagcagc gggagcatac gggcgaacag
     7861 gtcgggcagg acggcggcga gttcccggtg ctcctcgggg tgcacgttgt tgacgtacga
     7921 gcggaacacg acctggccgt cgtcgctgac gtcgacgtcg ctcggcagcc actggaactt
     7981 ctcggagaac tcgtgcttcg agtaggaggc cgtcgggttc cgccaggccc gctcgggccc
     8041 gccgctgacc tcccgcacca ggcagaacag ggaggggtgc accaggtcga gcacctggcc
     8101 gccggatccg ggatgccagt ccttctgctc ctcggggacc tcctccagca cccgcaccgc
     8161 ctcgcgcagc cgggagcgga gcccgtcgtc gaccagggtg tcggactgcc acaccccgtc
     8221 gacggcggac acctcgatgc cggtgccggc gtcccgaagc cgggcgtagt gcgcgagttc
     8281 ggcgaggacg tacgccacct gcgcctcggt gagtccctgg gcgacggctt cccgcgtcca
     8341 ccgggcgacg acctccgggt cgtccttctt gtcgaaccac ccctgcttgg cccggatatg
     8401 ggcgctgcac tgcatcatct caacctcccg cagggtgcgg ggggtcgcga acagtgcgga
     8461 gcgcacggac tcaaagggca gggggaaagc agacttgccg gtcaattgcc tcggcctttc
     8521 ggacggatgt gcgacgacgg gcaccatagc cgagccgacc gacaccccgc ccgcgcgccc
     8581 gccggctccg cgacttgccc gtgtgcggag ccggcgtacg gacccgggtg tcagcgggcg
     8641 gtgccccggg ggtggacttc catcggcacg tgatccgggt gggccatcgc ggacgccgct
     8701 tcccgcgggc tgtgcccggg gcacgggcgg agctgccacc gggacaggac cgtcgccagg
     8761 acgatcgtcg cctccgtcca ggcgaacgcg tcgccgatgc aacggcggtt gcccgacccg
     8821 aacggcacga acgcctcgcg gggtatgtcc ccccggcgct cgggcagcca ccggtccggg
     8881 tcgaagcggt ccgggtccgc gtacagtgcc gggtcgcggt gcagggcgta gaggctgaag
     8941 gcgacctccg tgcccgcggg gaggcggaac ccgcccagtt ccacctcctc ggtggtgcgg
     9001 cgcatgagca gcgtcacgcc gtggaggcgg atcacctcgt ccagcacacg ccggatcccg
     9061 accagccggg gcacgtccgc gatcgtcgcc ggacggcctt ccaggacctc gtcgacctcc
     9121 gccacgagct gcttctcgac ctccgggtgg cgggcgatct cgtggaacgc ccaggacagg
     9181 gtggaggccg tggtctcggt gcccgcgaag aggatcgtga cgagctcgtc gcggacctcc
     9241 tcgtcggtga gcgcctcccc cgtgtcggcg tcccgcgcgt cgagcaggac cgacagcagg
     9301 tcgcctccgc cctggtgccc ctcgcccgac cggcgggtgc cggcgatcac gtcgtcgatc
     9361 acctggcgca tgctgcgggc cgcggcgtcg aaggcgcggt tcggcgggat cgggaggtgg
     9421 tcgagcgcct tgggcgaggc cgcccggagc agcatgttct tcaggatcac gggcaggtcc
     9481 cggcgcaccg cctcgaccgc gggccgcccg atgtccgtgg agaacatcgt cgcggccagg
     9541 atctccacgg ccagctcgcc catgacctgt tcgaccgcga tcgtctgccc gggcgtccag
     9601 gagtcggcga gggcgcgggc ccggctgctc atcgtctcgg cgtagccggc gatgcacgtc
     9661 tggtggaaca tcggttggat gagcctgcgg tgccggcggt ggacgtcgcc tcccgccgtg
     9721 gccaggccgt tgccgaccag cgggcgcacg cggtcgtaca ggcggccctt ctcgaaggcc
     9781 cgcgcctggc cgacggtgac gtcgcggacg agggccgcgc tggtgacgac gtacatgggc
     9841 atgctgccca ggtccacgcg gaccaggtcg ccgacgtccc ggagcgaccg caggaacgcg
     9901 agggggtcgc gtcccagctt cagggcgtgg ccgagcaggg gcacccgccc gggcgcgggc
     9961 gggatcgatt ccagcccttg gggcacggtg aatcctttca tcagggggtg ggcgcgagca
    10021 gggcgggcat cggcatccgg gcgctcggca cgcgccgctg cggatccggg aggaggttcc
    10081 accaccagga gacggcgggg atctccaacg gctcgccgtc gtcgacgacg ggtgtctggc
    10141 ggaagctggt ggggaggctg gccgggtctt cgggggtggt gtagcggtgc gacgacacgc
    10201 cccagtcctg cgaaccccgg atgaagctgc cgagcccctg gaaatacgtg cgcagctgcg
    10261 ggctcgcctg gtcggcgagg ctctcctgca ggcgcatgaa gaggcacatc acgcggtcgc
    10321 gctgctcgat ggccgtggcc agcgcctgat cgggcgtcag gccgcgttcc tcctggagca
    10381 ctcggatggc gttgaggtag tagccgtcgc cccggctctc cttgtggtgg gagaagaggt
    10441 cgttgtccca ggtgatgacg aaggaggcca tttcggtggc cgcccggacg tacggctggt
    10501 cgcgctcgtg catcggcagc tcgtacccgt gccccatctc caggagcggg tacaccacgg
    10561 tcgtcgcgcc gtcgtagagg cgcatcagcg tgtagtcggc cagggacggc accgtcccct
    10621 cgcggcggtg ggatgcctcc cacaccacgg agaagaagta ctcgcgcagg gcgttgcacc
    10681 aggccgcggc ctggccggcc gtgccgtggc gggagacccg gcgtgtcagg tcgcgcagcc
    10741 cgtcggcgag ggagtcgtcg aggagcatgg gcgcttccgg gttctgcgcc acgcgcagca
    10801 ggcggtgcag cacacccgcc aggtctcccg gtcttcgccc gagcgcgccc tcctcgcaga
    10861 agccgtcgtc gacggcgaag agccacagga cgaagtcgga gaggagggcc accaccggct
    10921 cctgccctgc gggcaggatg cgggcggcga acgtgccgat gctgtggcgc aggaggcgcg
    10981 tgcgcagctc gtcggacccc acctggaagg cctccgccca cgccgcggtg tgcgcttcga
    11041 cagcctggta ccgcgggtgg atggccggcg ggatgggcgt gtagatgggc gggactatga
    11101 gtcccggctc attcttcact cgtaatcgcc tttcagccgt cgtgcgacgc aactaccggc
    11161 ctgcgcgcag ctggcgtcgg tgaggctccc agctaagcct ggcgccatgc acgagtgatc
    11221 atcatcccgg cgcatcgtac ccatcggaac tggcgcgtcc aatagtgccc gcacatggca
    11281 cgtgcaggtg gggcggccaa accaccaggc atggggcgag cggcaccaca ccggctcctg
    11341 cctccggggc ggcgccggga gcccgtgccg ggcaactgcg gcaggaatca gcgcagtttc
    11401 agcagggact tccaccaggg ccggcgggcc gtcgcggtgt ggtgctgccc gtgctgccgc
    11461 gcgccggcgg tgaaggccga aaccggcggg tgcgccgcgg cgtccggctg cgccgtgggg
    11521 gccggggtga cgcggcgggg cgggaaccgc accggcagcg agttgacgcg tgtggacacc
    11581 caggacgtgg tcaggctgag ctcgtcggcc gcggcgcgga gttccaggcc gggcagctcc
    11641 gagaggagcg tgtcgatgcc ggcctccgcg atggccctgc cgatgtcccg gccggggcac
    11701 tcgtgcgggc cgctgctgaa cgccagatgg gaccggttcc cgtgcacggg gagggacagg
    11761 tcggagcgga tgtccgggtc gacgttgccg gccgccagcc cgaggagcag catgtctccc
    11821 tgccggatcg gctggtctcc gaggacggtg tcgcccgtcg cccagcgtcc ggggacgacc
    11881 gacaggggcg gcgcgtccca gaggacctgc tccagggcgt ccgggagggt catgtggccg
    11941 cccgcgaggc tggcccggaa ccgcgggtcc gtcagcacca tgcggagggt gttcgcgatc
    12001 aggttgaccg tggtctcgtt ggccgcgacg aggacgagcc gcaggtgctc caggacctcg
    12061 tcgtcggtga ggttggaggc gtggccgatc agccagctgg cgaagtcgcg gccgggtgcg
    12121 cccttcttct gctgcacgag ttcgcggagg gtgtcgacca ggaagtcgtt gctcgcgagc
    12181 gcggtctgac tgcccttcat caggtccagg caggcgctca ccagatgggg cccgtaccgg
    12241 tcgggcatgc ccaggagctg gcacatgacg agcatcggca gcttctccgc gtactgcgcg
    12301 accaggtcgg cctggcctga cagggcgaac gcgtccacca gctgcttggt gtgccgtacg
    12361 acgtaccggc ggattccgcg ccggtcgacc tgggccaggc tgtcggtgac ggcgccgcgc
    12421 agccgctcgt gctccgcgcc gtccgcgaac acgcagatgg gctgccagcc gaccgtcggc
    12481 cccaggggcg agtcgggtga gaccctgccc tcctggaagg cggtccagcg gcgcgagtcg
    12541 cgggagaaca gggtcggctt gcgcatcact tcgaggttct cgcgatgccc cagcaccagc
    12601 caggccggga ggtcgccgtg caggagtacg ggcgcgacgg cgccgtgccg ggcgcgcagg
    12661 gcctcgtaga aggcggacgg gtccgccagc gcctcggggc cgtacagccg ggctatcccg
    12721 gagccgccct gaacgtgcgc agggcagccc ggcggcggca ccgcgccatg gccgtgtccc
    12781 gggtgttctg gacgcaaggt actcacaggg cctccgtagc cgcggctgaa tgggatgagg
    12841 acacgcgctg cgcggaaccg ccgcgcgttc tcgtgtcacc ggcaccggtc cgacaaccgc
    12901 accacggcag ttgtacaaga tccaagcacc tcgcagcata acggcggcga attccggcca
    12961 gccatcgcgc aggatcccgc cagacgctcc cagggggccg tgtgctccgc gccccgcctg
    13021 atcaggtacg ggctgcggcc gtcagggccg ccgtgtcgac cacccgggcg aagccgccgc
    13081 cgtggaggga ggcggccgtc gcgcgggcca ggtcgtcggc cgtcacgggc cgtccgtccg
    13141 ggccggtcag gtcgaaggtg tgggtggcgt cgagggcgaa caggacgtcg tagccgaggt
    13201 tgccggccat gcgggcggtg gtctccacgc acatgttggt ctggatgccg gccagcacga
    13261 tccgggtgat gccggcctcc cgcagccatg cgtcgaggtc gggggtgccg tagaacgccg
    13321 agttcaccga cttcgtgacg agcagttcga ggccggcgcc gctgccgcgc cgggcctcca
    13381 cgtagtcctt gaaggcgttc cccgcggacc cggcccgcaa gggcgagccg gggctgaccg
    13441 agtcgtgccg gacgaagacg acgggccggc ccgtgtcctt ccaggccgtg atcagggagg
    13501 cgatgttgcc gtcggccgca gggttgttgc gggggcccca gtaggccgcg tcgtcgaagc
    13561 ccttctggac gtccacgacg accagcgcgg tgttctctgt gatctccatg ccgccatcct
    13621 gcccctcgcc ccgccctgct tccaggaggc aggaagacag cgatcgatgg tttactgccg
    13681 ccatgaaccg accggcgccg gcccaccgca tcgccctgct cgccttcccc ggcatccggg
    13741 ccttcgacgt ctcggtcgtc acggaggtgt ggggcgtgga ccgcaccgac cggggggtgc
    13801 ccgccttcga gctgcgccgg gtggccgccg ggcccgatcc ggtgccgatg cggggcgggc
    13861 tcgccctcac gccggaccgc accctcgcct ggctgccccg ggcccggctc gtcctcgttc
    13921 ccggcctgga cgagcacgcc gagccggcgc ccgagcccgt cctcgcggcg ctgcgccgcg
    13981 cccacgcgcg cggcaccgcc atcgccgccc tgtgcggcgg cgcgttcacc ctggcccagg
    14041 cggggctgct cgacggccgc cgggcgctga cccactgggc cctggccgac ctgctgcgcg
    14101 cccggcaccc gcgcgtgcgg gtcgggcccg acgccctgtt cgtcgaggac ggcaacgtgt
    14161 ggacctccgc cggcaccgcg gccggcatcg acctgtgcct gcacctggtg cgcaccgccc
    14221 acggggcgga ggccgccgcg gccatcgccc ggtcgatggt caccgccccg ttccggacgg
    14281 gcggccaggc ccagttcatc gagcgcccga cgccccgcac ggaccgcggc gcggacgcgc
    14341 tggccggcgt acgggcgtac gcactggcgc acctcgacga gcccctcggc gtcgccgcgc
    14401 tggccgcccg cgcgggcatg tcgccgcgct cgttcgcccg gaacttcgcc gccgccaccg
    14461 ggaccacgcc gctgcggtgg ctcctggagc accgcatcgc cgccgcgcag aagctgctgg
    14521 agcgcaccga cctgcccgtg cccgaggtcg cccggcgggc cgggttcggc agcgaggtga
    14581 ccatgaggca gcacttcgcg tcccgcctgg ggacgagtcc gcgcgcctac cgcgcctcgt
    14641 tcgcagggga agggtcgaac caagagccga attccggatt cgcgggctcc tcgtgatcac
    14701 acccgctccg ccgccgttgg tggtgcgggc agtgttcgag aaagagggtt cccgtgtccg
    14761 agagcatcat cggcgtcgtc gacatcgcga agagcgagct ccgcttcctc cggcacatgc
    14821 tcggcgatgc cggcgagaac gcctgggagc ggctgctcga atggttcatc gacgactggt
    14881 tccggctgga cgtgctcggg ctggagaacg tgcccgccga ggggcccgcc gtgctcgtcg
    14941 ccaaccactc cggcgcctgg gggctggacg cgttcgtcat gcagaaggcc ctggtgcgtt
    15001 cgctgcggcg gcctctgcag gtgctggccg cgcccttcgt cttccacctt ccggtgctgg
    15061 ggccgtacgc ggcgcgcaag ggcgccgtgc cgatcgacct gcgggccggc atgcagcacc
    15121 tggccggggg cgggctgatc acggtgttcc ccgagggggt ttcagggctg gagaagccgt
    15181 tccgcgagcg ctaccgactc cagccgttca acccgggctt cgccgtggcc gccctgcaca
    15241 cgggggcgcc gatcgtaccg gtcgccgtca tcggggccga ggagtcctcc ccccggatgg
    15301 gtgagctgcc cgcgctggcg aagttcctcg gccttccgtc ctttccgctg acgtccttct
    15361 tcccgctgcc ggcgaagtgg ctgatcacca tcggcgagcc ggtcgccccg cccgagcggc
    15421 cgcggggcgc cggggcccgc tcggcggccg cccggcggct ggccggggag gtccaggcgg
    15481 tcgtgcagga catggtcgta cgggagcggg ggcggcggga cacgctcgta cggtagcggc
    15541 ggcgaccggg cgggcgggcc cggacgccgc ccggcccgcc cggcctgcct gcccgtccgc
    15601 ggtcagtccg cgaggcggcg ggcggcctcg cggatgtcgg aggcggcgcg ggtgcaccgg
    15661 tcggcgtgct cgagcagccg catccggaag cgctcgccgg tctcgctccc gtcccagccg
    15721 gcgtcggcgg cgcaggcggc cagactgcgg gcgtgccggt cgaggcggcc ggcggcggct
    15781 cgggccggcg ccgcgtacga ggccggggtg ccggcgcgcg cgggcggcgc ggcggcgggt
    15841 gcgccggcgg cggggaacgc gagcagcagc gtgcgcgggt ccagggtgag cggcatccgg
    15901 tcgggggaca gcgcgggcgc gaggagggcg ggccgggctc cctcggcgtc ctcggtgaag
    15961 aaccggacga ccgcttcggc gacccggacg gcgaccgcgg cggccgcaca gccggtgggc
    16021 gatccgcaca gcggggacgg cccgcctccc ggcagcgggc ccggctccgc cccggcgccg
    16081 ccggcgtggt cggtggcgct gcggagccag ccgggggcgg ccaggatctc cgtgcccgcg
    16141 tcgacggcga gcccctccca ggagaaccgg gaccggaccg ggtgcacggc ggcgccgacg
    16201 ggcgggaagc ggtcgagggc gagggccacg gcggcggccg gtccgcctgc cgccgcgggc
    16261 acgcccgcgg cggtgagggc cagcgcctgg agggccgtgg tggcggctgc ttcggagacc
    16321 acggcgaggg cgtgggccag ggcctcctcg ggccggcccg caccggccgg ggggccgtgc
    16381 tccgcgcggg cggcgggcac ggcggggcct gctgcggggc gggcaaggac ggcggccagg
    16441 gagtcggggt ccgggtcggc caggtagggg gcgaggcgcc ggtgcacggc ggcggcccgg
    16501 gactcgtagg cgtggctgcc cgcggcctcg gctgcccggc ggagcatctc gccgagcagc
    16561 gtgtcctcgg ccgcggccgc gcccgccacc accctgcggg cggcgcgcag caggcccggc
    16621 cgccatgcct cccaggtcag ggcctggtcg tcgcggcggg cggaggccag ccggcggagt
    16681 tccccggcga gcgggccggc gagcgcggct tcaggcagga cgtcctcggg cggggcgggg
    16741 agcggcaggg ggtggtgggg gtgcaggccg tgccggcgcc cggcttcgtc gagccggacg
    16801 gcgggggcga gcgcgtcggc ggcggcgccg gccgcgagga gccccgcggt gtcggccggc
    16861 ttgagcggga cgaggaagga gccgagcggg gtccgcagcc tgacggggcg cccggagcgg
    16921 ctgcggcgca ggtgggcgag gacgccgcgg gcggcgccct cgcaggtgag ggagtccagg
    16981 ccgagggcgc gggcgggcgc gtccgaccag ggcaggcggc gggcgagcag ggccgcgctg
    17041 aacacggcgt tctccagcgg cagggcggcg gcgggggtgg tcatcggggg tggttctccc
    17101 tcgggtcgta cggggggacg ggcgcggggg cggggcagca gcgggcggag gcgcgttcgc
    17161 gggcggaccc gggggcgcga gcgggcgcac actccggcgc gggccagggc gctggacggg
    17221 gggcgggacg gggggcggga cgggggcgga accaggctcg gggccggtca cctgtcgcgc
    17281 agcatgtacg gctggttgcc gatgatctcg ccgtcgtagc tgccgatcag cgcgttcacc
    17341 cggtcccggt ggtgggccag ttcaccgcgc aggctgtccg agtacgcctg gggggcgtgg
    17401 gagagcgggt agtcgtagga ctcgtcgagc caggagagct ccacccagct gtcggggacg
    17461 tcgtggggcg aggcgggccc gcggccgtcc agcatgggga tgacgtcgtg cttgttgacc
    17521 aggctgacga cccgggtggt gtggtcggcg ggccgcttgt tgtcgatcgg cgagccgagg
    17581 gtgacgacgt gggtgatccg gtactcggag gcggtgtcga ggtcggcggc gaggttcatc
    17641 gcggtcaggc cgccgaggct gtggcccacc atcatcagct ccgacccggc gggcaccccg
    17701 gcccgcttca ggagcttcct cgccgcccgg gtgtaggtgg tgtcggtgcg caggcagccg
    17761 tcgaacgcgc cgaccaggtc ctgcggggtg ctgttgctga gcagggcgaa gctggtgccg
    17821 gggagcagca ggacgtggcg tacggctccg tcggtgcagg cgatgcggcg caggaggacc
    17881 aggccgtggt tgccgagggc gccgatgtcg ttgatgtagc tgacaatgtc gttgcgggag
    17941 gtgccgagga ccttggcgag gatcgggtcg gggtcggcgc gctcggcgcg gcccgggccg
    18001 gggttgaggt gcttgatcag ggagcagggc aggccgaaga gcgggtcggt ggtggggacg
    18061 ccgcccgcga gggtcaccca ggagaagctg tcgttgacgg ggttctcgtc caacaggccc
    18121 agcagggcca ggagttccat gatgacgggg ctgatggtgg tgagggcgcg ggtgacgccg
    18181 agccgctcga cgagggcgtg gagggcgcgc gccgcctcca gccggtctcc tgcgacgagc
    18241 gcgtcggtga ggcgccgggc gtggggggag tccagattgg ggtgggcggc ggtggcggcc
    18301 tcgatgcgca gggcgaaggc gtcgacggcc atggcgacgg aggcgggccg gcggcgggtc
    18361 aggttgcccg cgatgcgggc gagttcgccg acggtgccgc cgttggcggc gaagccgagg
    18421 ccggcccggc tggtcagggc gcggaggcag gacagggtcg caccggcggc ccaggcgggg
    18481 cggcgcaggg cctggagggc gaagctgccg ccggtgaggg ctgcggtgag gtgcgcgccg
    18541 gcctggcggg cggcgagggc ggcgtcggcg aggaggacgg aggccgcgat gaggaggtcg
    18601 ccgtccgccg gggtggccgc ggcggtggcc tccgggctgc cggcggggcc cgcgtcgggg
    18661 agggccgggg tgtcgcaggg cccggggagc gggccggcgt cggggatgtc cttgcgccgc
    18721 ccgtctgtga ggtgccgggg ggatgcgccg gtcgcctggg gtgtcacgct gcaacctctc
    18781 gtcgtctgaa gccgctgtcc gcgacgcatg gtggcaccga acgggggcgc ctccggcgcg
    18841 gccgggcgca cgctcccgcg cgcgcggcgc ctgccatacc ccgcgcgccc cgcagccgcg
    18901 ggggtgcggg cccccgcaca gccgttcacg ggcccggctc gtcggggggt gacgggagcg
    18961 gggcgcggtt gacgcccggg cgcggaaagc gctggcggcg ggcgcgggcg gattgcgagc
    19021 atgcgggggt gagcacagcg gggaacgaac tgatcgacgt ggtgccgctc ggcaccgtcc
    19081 gggcgcgggg caccgtcgag gcggtcgccg gagggcggct cctcgtccgt gcaggcgggc
    19141 tgctggaggt gcacgaccgg gaggagttcc tcgccggcac ggccgccggc ccggtcgcct
    19201 ccctccgggt ggaggagcag gagcgggcgg ccgccgcctc cgacggcggg ttcctggtgg
    19261 cgggcgcggc ctccgtacgg gccgtgggcc cggacggcgg gacgcggtgg gagttcgccc
    19321 acgacccgtg gcacggcacc ccccgcgccc ggtccgcgcc ggcgcccagc ccggacggcc
    19381 gcctggtcgg cgtcgtcgtg ccgacgcagg agcccgaccc ggcgcgggcg gccctggtgt
    19441 acgacgccga gccggggcgg agctacgtct gggaccggct gctgttcctg gacgcggcga
    19501 gcggcgaggt cgtcggccgg cagcagctcc gctcgctggc gtcgggcgtg gtgctgggct
    19561 ggcgtccgga cggcggcgcc ctggcggtgt cctgctggac cgcctggcac agctggtcga
    19621 cgtggtgggc cgagcccacc gggtccgcgg atgccgacga cgggatccgc atcgccggcg
    19681 gtacgtggat gcacgcgctg gcgggcttcc tgcccggctc ccgcaccctg acccagcggt
    19741 atgccgagca cgtctggccc gacgacgacc gcgacgagct ggccgtgtac gacaccggtt
    19801 ccggcgggca ggtggccgtg ctcgacctgg cggcgctggc ccccgacccg gcggaggacg
    19861 agttccgctc cgccggggtc ctcgacgggc gccacgtcct ggtgccgggc cgcgtgttcc
    19921 gggcgggcgg gccgccgcag gcgcggcact ggctgatcga tgcggcgtcg ctgcgcccgc
    19981 tcggccggct ggcgtacccg gccgccgtcg gcagggacgt gaccgtcctg ggcgacggca
    20041 cctggctcac ggaggacgac ggcggccgcc tgcaccgctg ggccctgggg cgtacggagc
    20101 gcgccgcctc cggctgatcc cgggcggccg cggcccgctc ccggtcagcg caggccgtcg
    20161 aagaaggcgc gcaggtcgag cgcagctgcc tgctgcacct gggcggcggc tccgcccgcg
    20221 acctggcctg gatgatcact tcggtcgaca ccggcttcag ccttgccgag gccccgcccg
    20281 agccggccga agccctggcc gcccaggcgg cccgctgcct cggcgccgta cgcgcggcgc
    20341 cggcggcgcg ggaggaggcc gccctcaggg ccgggaggtg aggtcggggc ggcggaggcg
    20401 gaaggtgcgc cggtaggtgt ccggggggac gcggacggtg cgccggaagt ggcggcgcag
    20461 ggtggtggcg gtgcccgtgc cggtggcagc ggcgatcacg tcgtccgtcg tctccggcag
    20521 ggcccggtcg cgccggatgc gctgggctcg gcggccgcac ccggacggcg ggtgccgccg
    20581 ccgcaggccg gctcttcgac gcggcggact tcccgggcgc cctgcagggc agcctccggg
    20641 tcgacctgcc cgcatgcggg ggcggccgcg gttcgcggag ccggccgggc gtcccgtacg
    20701 cctgcgaggg ctgcggcggg ggtcccggcc ggagcggcgc gcagccgggc tcagccgccg
    20761 gcctgcgtgg gcgttccgta cgcggcccgg acggccggcg ggagcgtgaa ggggaccgcg
    20821 ccgcccgccc gtacggcgtc cacagcaccc tggtggacgg tgcggccgac ctcgggcgtg
    20881 ggacagggca cggggcttcc ggccaggggg taccactcgg tgtccccgac gtactgcacg
    20941 cagacgtgcg cctgctgcgg ctcccacacg gtgcgcaccg cgagctctcc ggcgagcgtc
    21001 ccggcctccg ccgtgcgtac gcctccgggg cccgtgaaca cccccgtggt ggtccatgtc
    21061 gtggatgcca tgtcagtcac ctcgggcagc agtggtggtg tgactgccat gctgccctg
//
