LOCUS       NZ_CP030862            12964 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces globosus strain LZH-48 chromosome, complete genome.
ACCESSION   NZ_CP030862
VERSION     NZ_CP030862.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces globosus
  ORGANISM  Streptomyces globosus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6863360)
  AUTHORS   Ran,K., Li,Z., Wei,S. and Dong,R.
  TITLE     Draft genome Sequence of streptomyces globosus LZH-48
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6863360)
  AUTHORS   Ran,K., Li,Z., Wei,S. and Dong,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2018) Institute of Biophysics, Dezhou University,
            566 DaXuexi RD, Dezhou, Shandong 253023, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Portal v. version 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003325375.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:22:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,671
            CDSs (total)                      :: 6,576
            Genes (coding)                    :: 6,458
            CDSs (with protein)               :: 6,458
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 41 of 118
            Pseudo Genes (incomplete)         :: 101 of 118
            Pseudo Genes (internal stop)      :: 11 of 118
            Pseudo Genes (multiple problems)  :: 32 of 118
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:39:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1834191
            Orig. end                         :: 1847155
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030862.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..12964
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="6"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12964
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12964
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7964](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7964
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     misc_feature    complement(135..149)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.15"
                     /tool="antismash"
     misc_feature    complement(156..169)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            159..677
                     /locus_tag="C0216_RS34050"
     CDS             159..677
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C0216_RS34050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216827059.1"
                     /transl_table=11
                     /translation="MIMRRGIIAAAVAGAAGVALGLTPVSGAFAAQTGLTPETRQDWRC
                     SDDRRGSNDWYECCERYNRWEDRPDWCWDKDKAHHSNRDYDRYDYRDYNHRDYNDRDYN
                     DRGGNGHDNRGGNGHDGGGGGNGGHGGNGGGGGGGHGGGGGGNGGGGGGGGHGGGGGNG
                     GGGGGGGGR"
     gene            complement(838..2208)
                     /locus_tag="C0216_RS08460"
                     /old_locus_tag="C0216_08455"
     CDS             complement(838..2208)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543307.1"
                     /locus_tag="C0216_RS08460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_08455"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_114054672.1"
                     /transl_table=11
                     /translation="MTEAPSRLNTGSHDLPVSPELSRYMAGNWAPSPLPDSERVSAYAV
                     TPARRARLSARFPGERLVVPAGELKVRSNDCDFRFRPHSAYAWLTGLTGEDQVGHVLVM
                     EPSGPHGHEAVLYLRPRSPRTGGSEEFYRDRRYGEFWVGRRPDLAEAERLTGLRCAHLE
                     SLGDPVGRNAATDAELATALSELRLVKDAWEVGQLQLAVDHTAAGFEDVVRALPRALAH
                     PRGERWIEGVFGLRARAEGNGTGYDTIAASGAHACVLHWIRNDGRLDPGELLLLDAGVE
                     TDTLYTADITRTLPLSGRFSPVQRQVYELVLAAQEAGIAALRPGASFRDFHRAGMRVIA
                     EGLADWGVLKDAEGDLHRRYTLCSSGHMLGLDVHDCAKARADTYLDGVLEEGQVLTVEP
                     GLYLQPDDETLPPELRGIGVRIEDDLVVTATGARLMSGALPRTVAGIEEWMGGLLEG"
     misc_feature    complement(2218..2233)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.89"
                     /tool="antismash"
     misc_feature    2259..2269
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    2263..2276
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.09"
                     /tool="antismash"
     misc_feature    complement(2301..2314)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     gene            2426..4876
                     /locus_tag="C0216_RS08465"
                     /old_locus_tag="C0216_08460"
     CDS             2426..4876
                     /EC_number="3.4.24.3"
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267147.1"
                     /locus_tag="C0216_RS08465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_08460"
                     /product="collagenase"
                     /protein_id="WP_114054673.1"
                     /transl_table=11
                     /translation="MSQHRAVRSSLLSTAVAVTLLATAGQAVTVAAETAVPAPAQGAAA
                     APAAPAPAGARGGNPFDEVDRLASPKEAAPASAVAPGAGRTPGGQAARSAADAAAAQAA
                     QGRTPGAPTAAAPASERAEKSRKAAAAAPATGRTLAAGVPCTLDGVTGLSPEQFADFLA
                     DEAVTADGCLRSIIWTWDARLAPVMSDAHVQAVSRRISALAAAHDGKNSSHLEEMFTYL
                     HAVAYHDYSRSEIDVTDAPTVEAMRRAIADFGAAARTFDTTASNARTLREALYAGSAPG
                     LRHHQLGLIKKVLATMDPGHPATHHDPHWAGAALAALSVNYLGVYPGNQDAAFHAAVAA
                     DPAYRDLFKAFAGYGHLKGTANAWVARDALGEYGRFGQVPSLKDRVVADLGALLPTARA
                     TFGDGSEQWAKVVSWLNFYEACKPYGVCKEDIEKQLFPNTFTYDNGAIKVRTALDRATV
                     DQLYYASKQVKAQYHRVIGTEQPLAGDPNSTLNIVLYASRADYVNYHPILTGYDTNNGG
                     IYIENGATFYTYQRRVPQDSSLTLEELFRHEYVHYLNGRFAVHGFFGQGPWYEGDRTTA
                     MDEGTAEFFDGATRSDGIAVRKSLVKSIISDTAGGGPRMSVEQILNATYDGDGFRFYSY
                     AGTFFEFLWTEKPSLLREMYTHLRNNDVAKYDAWRHRLGSDSYLQRDYDRFLDTQIAKV
                     DQLFVPNTTYTPNEQLRDSALASVKSSFAAATYNTPDCVENGDPGKRRFTCTGRITANL
                     KNWRSDDQNFKDMSETVDYFILDRAGAASNNLADMNCSFGPVEIWDNRTAGTSPYSCEG
                     PLRS"
     gene            5001..6170
                     /locus_tag="C0216_RS08470"
                     /old_locus_tag="C0216_08465"
     CDS             5001..6170
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237882.1"
                     /locus_tag="C0216_RS08470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_08465"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_114054674.1"
                     /sec_met_domain="DAO (E-value: 7.8e-65, bitscore: 218.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKRHPLDVVIIGAGVVGAACAYYAARAGLRAAVVDRGPVAGGTT
                     GAGEGNLLVSDKEAGPELDLALLSAGLWRDLAAALPEELEYEPKGGLVIAPDEAALKAL
                     RAFAEGQRAAGVEAVEADPAELRELEPHLAPGRAGGFLYPQDAQVQPAQAAARLLAASG
                     AELHLGEEAVEVVTAGGAVRGVRTARRELAAPAVVNAAGTWGGRIAELAGTSLPVLPRR
                     GFVLVTEPLPRVVRHKVYAADYIADVASGSAALQSSAVVEGTPAGPVLIGATRERVGFD
                     RSLSPEALRRLAGQAAALFPALADARILRAYHGFRPYLPDHLPAIGPDPRVPGLVHACG
                     HEGAGIGLAPATGVLVAAALTGAEPPLPLHPFRPDRFPEPAAQPKETGR"
     misc_feature    5020..5034
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.01"
                     /tool="antismash"
     gene            6167..6496
                     /locus_tag="C0216_RS08475"
                     /old_locus_tag="C0216_08470"
     CDS             6167..6496
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018850111.1"
                     /locus_tag="C0216_RS08475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_08470"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_174250365.1"
                     /sec_met_domain="Fer2_4 (E-value: 2.4e-25, bitscore: 86.9,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDPSHRRSPRDLVGGRPDATYTLRFDGRELTAHAGQSIAAVLWG
                     AGILAWRTTRQGGAPRGAFCGIGSCYDCLVTVNGRPNQRACLVPARPGDAVTTQEGTGR
                     ADLAV"
     gene            6477..7964
                     /locus_tag="C0216_RS08480"
                     /old_locus_tag="C0216_08475"
     CDS             6477..7964
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018850112.1"
                     /locus_tag="C0216_RS08480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_08475"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_114054675.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.9e-25, bitscore:
                     87.6, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 6.1e-11, bitscore:
                     41.0, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTSPSDLPGPGAPAAAGRPDAAPADLAVVGAGPAGLAAAVTAAR
                     LGLRVTLLDAGERPGGQFYRHPAPQLGAERPEALHHGWAAFAARERALRAHTASGRVTY
                     LPGHHVWTVVRRDAPQDTAPAGAARRAPAAWVLHAVAGPEERAVAVPARAVLLATGSYE
                     RQLPFPGWTLPGVVGAGGAQAMLKAGLVLPGRRVVVAGSGPLLLAVAGSLASAGARVPA
                     VVEAAAYTGYAPALPALLRNPAKLAEGAVYGGALLRHGVRLLTRHAVTEAHGTDRVEAV
                     TVARLDADWRPLPGTARRIPCDAVAVGHGLVPQLELATGLGCATRRAADGTAALDLDAL
                     QRTSVPGIWSAGETGGIAGAEPALVEGEIAAHAVAGRPVPAALVRRRARLRAFADAMGR
                     VHRPGEGWTGWLRDDTDVCRCEEVPAGRIREAVSDLGARDARTAKLLTRAGMGWCQGRM
                     CGPAVAALAGEEQAPDRRPLSCPVPLRLLAGLPPADG"
     misc_feature    complement(8046..8060)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.37"
                     /tool="antismash"
     misc_feature    complement(8055..8072)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 13.96"
                     /tool="antismash"
     misc_feature    complement(8061..8077)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     misc_feature    8067..8077
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            8101..9030
                     /locus_tag="C0216_RS08485"
                     /old_locus_tag="C0216_08480"
     CDS             8101..9030
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267151.1"
                     /locus_tag="C0216_RS08485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_08480"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_114054676.1"
                     /transl_table=11
                     /translation="MTDAHTPAPTAADPRTRPWHGIMVATALPMREDLSVDYDAYADHV
                     AWLIANGCDGVVPNGSLGEYQTLTDEERARVVRTAVEAAGDGSRVMPGVAAYGSAEARR
                     WAEQAAEAGAGSVLLLPPNAFRADESAVRSHYAEVARAGLPVVAYNNPIDTKVDLTPAL
                     LARLHADGSIVAVKEFSGDVRRAYEIAELAPGLDLLIGADDVLLELALAGAVGWIAGYP
                     NALPAACATLYRAAVAGDLDTALPLYKSLHSLLRWDSKTEFVQAIKLSMDLAGRPGGAT
                     RPPRFPLTGETEAAVRAATEKALAEGLN"
     gene            9047..10051
                     /locus_tag="C0216_RS08490"
                     /old_locus_tag="C0216_08485"
     CDS             9047..10051
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891275.1"
                     /locus_tag="C0216_RS08490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_08485"
                     /product="proline racemase family protein"
                     /protein_id="WP_114054677.1"
                     /transl_table=11
                     /translation="MRTRHIYHAVDSHTEGMPTRVVTGGVGVIPGATMAEKRLHFIEHM
                     DHVRTLLMYEPRGHSAMSGAILQPPTRPDADFGVLYIEVSGLLPMCGHGTIGVATVLVE
                     TGMVPAVEPVTTVRLDTPAGLVSVDVRVEDGAATAVTLTNVPAFCAGLDLKADVPGYGT
                     VTYDLAYGGNFYAFVELDALGLPFDRARKDDLLAAGLAVMDAVNASADRPVHPEDPAIA
                     GVKHVYLAAPGSDARRSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGLLGLGADFVNE
                     SFIGTEFTGRLVGRTTVGGYEAVVPAVTGRAWITGTAQYFLDPSDPFPGGFLL"
     gene            10048..11118
                     /locus_tag="C0216_RS08495"
                     /old_locus_tag="C0216_08490"
     CDS             10048..11118
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267153.1"
                     /locus_tag="C0216_RS08495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_08490"
                     /product="proline racemase family protein"
                     /protein_id="WP_246042396.1"
                     /transl_table=11
                     /translation="MTADDPAAPEVRTADYHAAGEPFRIVDTADPGLPPAPGDTVAERC
                     ATAIGPGGSGTAPRPGALDSVRRLLVQEPRGHAGMYGGFVVPPDDDGAHFGVLFWHKDG
                     YSTACGHGTMALGAWAVDTGRVPAPDEGDVPVRIDVPSGRVAATVHRSGGRTTGVTFRN
                     VAARVGARKVPVATSLGLAEADIAHAGACYASVRARDLGLDVSRASLGDLVRAGREIRT
                     ALAAHPATWHPDGPLLSGVYGVIFHEELPDTPFGPHQRNVTVFADGQVDRSPCGSGTSA
                     RLALLAEDGRLGPEDSLLHESVAGTVFTGRIAPAAAAPGEAPDGLVTEVTGSAYRTGEH
                     RFTLDPHDALGAGFLL"
     gene            11118..12068
                     /locus_tag="C0216_RS08500"
                     /old_locus_tag="C0216_08495"
     CDS             11118..12068
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038315.1"
                     /locus_tag="C0216_RS08500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_08495"
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_246042792.1"
                     /transl_table=11
                     /translation="MRQIGAAEITALLGPAAAADALADALRAGLDPEACPQRSAVAVPG
                     GGELLLMPAAQGAYAGVKIAGVAPGNPARGLPRITGSYLLLDGPTLSPVALLDGAALTA
                     LRTPAVSALALRHLAPAGRPLRLVLFGTGPQAYGHLEAAAAVRELAEAVVVGRDPGGPG
                     AKALAEHARTLGVPARTGSAADVAGADLVLCCTTARTPLFDGRLVAPGAVVVAVGSHEP
                     DARETDTALVRRSAVYVEARSAALREAGDLLVPEAEGAIGPGCITATLADLVAGRAPGP
                     GPAGCPQLFKSVGMAWEDLAVAVALYAAAGKNSET"
     gene            12110..12829
                     /locus_tag="C0216_RS08505"
                     /old_locus_tag="C0216_08500"
     CDS             12110..12829
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267155.1"
                     /locus_tag="C0216_RS08505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C0216_08500"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_114054678.1"
                     /transl_table=11
                     /translation="MGDLKQHSLIKAQERLRDQVGHALRAALIAGELRPGSVYSAPGLA
                     AELGVSATPVREAMLDLAREGLVEPVRNKGFRITEVSERDLDQYTELRTMIEVPTVGRV
                     TRMAAREQLEALRPIAEEIVTSAREHNLIGYLEADRRFHLTLLGLAGNERLVETVGDLR
                     KRSRLYGLTGLDEAGKLVSSAEEHLELLDLMIAGDAEAAEACMARHLGHVRSLWAEGRD
                     EPVGRPAAGGLGSGLTG"
ORIGIN
        1 gtcggaagcg attccgcatt ccggggatcc cagtggggaa gcggcctgcg gggggtcgcg
       61 gggtgcggca caggcgagcg gcctttgaca gggagcagga gaggggggag tgtggaaatg
      121 ccccctttgg gaccaattgt caaggcattc ggaggtgcat gatcatgcgc cgtgggatca
      181 ttgcggcagc tgtggccggc gccgcgggcg tcgctctcgg cctgacgccg gtgagcgggg
      241 cctttgccgc gcagaccggg ctgaccccgg agacccggca ggactggcgg tgttcggacg
      301 accggcgcgg cagcaacgac tggtatgagt gctgcgagcg ctacaaccgg tgggaggacc
      361 ggcccgactg gtgctgggac aaggacaagg cacaccacag caaccgcgac tatgaccggt
      421 acgactaccg cgactacaac caccgcgact acaacgaccg cgactacaac gaccgcggcg
      481 gcaacggcca cgacaaccgc ggcggcaacg gccatgacgg cggcggtggc ggcaacggcg
      541 gccacggcgg caacggcggc ggcggcggtg gcggccacgg cggcggcggt ggcggcaacg
      601 gcggcggtgg cggcggtggc ggccacggcg gcggtggcgg caacggcggc ggtggcggtg
      661 gcggtggcgg caggtaactc cgcacaccgg aactgaaccg cccgttcatt ccgcatcccg
      721 aacacgccgg aggaaaccgg caggtgacgg tccgcgcctc ccgcgcgggc cgtcactgct
      781 gtccgcaccc cgctgccaca ccccccgagg ccgcggcggg gcgtcggagc ctcgggctca
      841 accctccagc aggccgccca tccactcctc gatcccggcc accgtccgcg gcagggcccc
      901 cgacatcagc cgggcccctg tcgcggtgac gaccaggtcg tcctcgatgc gcaccccgat
      961 gccgcgcagc tccggcggca gcgtctcgtc gtccggctgg aggtagaggc ccggctcgac
     1021 cgtcaggacc tggccctcct ccagtacccc gtccaggtac gtgtccgccc gcgccttcgc
     1081 gcagtcgtgg acgtcgagcc ccagcatgtg gccgctgctg cacagcgtgt accggcggtg
     1141 caggtcgccc tcggcgtcct tgagcacgcc ccagtccgcc aggccctccg cgatcacccg
     1201 catcccggcc cggtggaagt cgcggaagct cgcccccggc cgcagtgcgg cgatgcccgc
     1261 ctcctgcgcc gcgagcacca gctcgtacac ctgccgctgg acgggggaga agcgccccga
     1321 cagcgggagg gtgcgcgtga tgtcggccgt gtagagcgtg tcggtctcga cgccggcgtc
     1381 gagcagcagc agctcgcccg ggtcgagccg cccgtcgttg cggatccagt gcagcacgca
     1441 cgcgtgcgcg ccggacgcgg cgatggtgtc gtagccggtg ccgttgccct ccgcccgggc
     1501 gcgcaggccg aagaccccct cgatccaccg ctcgccgcgc gggtgggcga gcgcgcgcgg
     1561 cagcgcccgt acgacgtcct cgaacccggc ggcggtgtgg tcgacggcca gctggagctg
     1621 cccgacctcc caggcgtcct tgaccaggcg cagctccgac agggccgtgg ccagctcggc
     1681 gtcggtggcg gcattgcggc cgaccgggtc gcccagtgac tccaggtggg cgcagcgcag
     1741 cccggtcagg cgctccgcct ccgcgaggtc ggggcggcgg ccgacccaga actccccgta
     1801 ccggcggtcc cggtagaact cctcgctgcc gccggtgcgc ggggagcgcg gacgcaggta
     1861 cagcacggcc tcgtggccgt gggggccgga gggctccatc acgagcacgt ggccgacctg
     1921 gtcctcgccg gtgagcccgg tgagccaggc gtacgcgctg tgcgggcgga agcggaagtc
     1981 gcagtcgttg gagcggacct tcagctcgcc cgcggggacg accaaccgct cgccggggaa
     2041 gcgcgcggac aggcgggcgc ggcgggcggg ggtgacggcg tacgcggaga cgcgctcgga
     2101 gtccggcagg ggcgacgggg cccagttgcc ggccatgtac cgggacaact caggcgatac
     2161 cggcagatcg tgactcccgg tgttgaggcg ggagggggct tcggtcacgg gggctccctg
     2221 ggaaagacgt gaactggtgt gcgcacaggt cttgccagtg caatttcaca ttactatgtt
     2281 acagctcaca ccgcggcgcg ttaatccccg tcaaacgccg tgtggcgcag ggcagttcac
     2341 gcacgaccgc tcgtccggca cgtcccacgc agcacccccg cgccgtgtcc gccatgtccc
     2401 ccacctcccc ttccaggagt ccttggtgtc ccagcacaga gctgtgcgtt cctccctcct
     2461 ctccaccgcg gtcgcggtga cgctcctcgc cacggcgggc caggccgtga cggtggccgc
     2521 cgagaccgcg gtccccgccc cggcgcaggg cgcagccgcc gcccctgccg ctcccgcacc
     2581 cgccggggcc cgcggcggaa acccgttcga cgaggtcgac cgcctcgcct cgccgaagga
     2641 ggcggccccc gcttccgccg tcgcgccggg cgccgggcgc accccgggcg gccaggccgc
     2701 ccgttccgcc gcggacgccg cagcagccca ggccgcccag ggccgcaccc cgggagcccc
     2761 gacggcggcc gcgccggcct ccgagcgcgc agagaagagc cgcaaggccg ccgcggcggc
     2821 ccccgcgacc ggccgcaccc tcgctgccgg cgtcccctgc accctcgacg gcgtgacggg
     2881 gctgtccccg gagcagttcg ccgacttcct cgccgacgag gccgtcacgg ccgacggctg
     2941 cctgcgcagc atcatctgga cctgggacgc ccgcctggcc ccggtcatgt ccgacgccca
     3001 tgtccaggcc gtctcccggc gcatatccgc cctggccgcg gcgcacgacg gcaagaactc
     3061 ctcccacctg gaggagatgt tcacctacct gcacgcggtc gcctaccacg actactcgcg
     3121 ctccgagatc gacgtcaccg acgcgccgac cgtcgaggcc atgcgccgcg ccatcgccga
     3181 cttcggcgcc gccgcccgca ccttcgacac caccgcctcc aacgcccgca ccctgcgcga
     3241 ggccctctat gccggcagtg ctcccggcct gcgccaccac cagctcggcc tgatcaagaa
     3301 ggtcctggcc acgatggacc cgggccaccc ggccacccac cacgacccgc actgggcggg
     3361 tgccgccctg gccgcgctct cggtgaacta cctcggcgtc tacccgggca accaggacgc
     3421 cgccttccac gcggcggtgg ccgccgaccc ggcctaccgc gacctgttca aggcgttcgc
     3481 cggctacggc cacctcaagg gcaccgcgaa cgcctgggtc gcccgcgacg cgctcggcga
     3541 gtacggccgc ttcggccagg tcccctctct caaggaccgg gtcgtggccg acctcggcgc
     3601 gctcctcccg acggcccgcg ccaccttcgg cgacggcagc gagcagtggg cgaaggtcgt
     3661 ctcctggctc aacttctacg aggcgtgcaa gccgtacggc gtctgcaagg aggacatcga
     3721 gaagcagctc ttcccgaaca ccttcaccta cgacaacggc gccatcaagg tccgcaccgc
     3781 cctcgaccgg gccaccgtcg accagctcta ctacgcgagc aagcaggtca aggcgcagta
     3841 ccaccgggtg atcggcaccg agcagccgct cgccggcgac ccgaacagca ccctcaacat
     3901 cgtgctgtac gcctcgcgcg ccgactacgt gaactaccac ccgatcctga ccgggtacga
     3961 cacgaacaac ggcggcatct acatcgagaa cggcgccacc ttctacacct accagcgccg
     4021 cgtcccgcag gactccagcc tgaccctgga agagctcttc cgccacgagt acgtgcacta
     4081 cctcaacggc cgcttcgccg tgcacggctt cttcggccag ggcccctggt acgagggcga
     4141 ccgcaccacc gccatggacg agggcacggc cgagttcttc gacggggcca cccgctccga
     4201 cggcatcgcc gtgcgcaagt cgctcgtcaa gagcatcatc agcgacacgg cgggcggcgg
     4261 cccccgcatg agcgtcgagc agatcctcaa cgcgacgtac gacggcgacg gcttccgctt
     4321 ctacagctac gccggcacgt tcttcgagtt cctgtggacc gagaagccgt ccctgctgcg
     4381 cgagatgtac acccacctgc gcaacaacga cgtggcgaag tacgacgcct ggcgccaccg
     4441 cctcggctcg gacagctacc tccagcgcga ctacgaccgc ttcctggaca cgcagatcgc
     4501 caaggtggac cagctcttcg tccccaacac gacctacacg ccgaacgagc agctgcgcga
     4561 ctccgcgctc gcctcggtga agtcctcgtt cgccgcggcc acgtacaaca cgccggactg
     4621 cgtcgagaac ggcgaccccg gcaagcggcg gttcacctgc accggccgga tcaccgcgaa
     4681 cctgaagaac tggcgcagcg acgaccagaa cttcaaggac atgtcggaga cggtcgacta
     4741 cttcatcctc gaccgggccg gcgcggcgtc caacaacctg gccgacatga actgctcctt
     4801 cggcccggtg gagatctggg acaaccgcac ggccggcacc tccccgtaca gctgcgaggg
     4861 cccgctgcgc agctgacccg tgccgccggc ggccggccct gcactccggg agaccccgga
     4921 gcggggggag ggccggccgc cggaccgtcc cgctgctgca cgctctgggc agccgctaaa
     4981 gaatgtgaca tattactgcc gtgcccaaga gacatcccct ggacgtcgtg atcatcggag
     5041 ccggcgtcgt cggagcagcg tgcgcctact acgccgcacg cgccggcctc cgcgccgccg
     5101 tcgtcgaccg cggccccgtc gccggcggga cgaccggagc gggcgagggg aacctcctcg
     5161 tctccgacaa ggaggccggc cccgagctcg acctcgccct gctgtccgca ggcctctggc
     5221 gggacctggc cgccgccctc cccgaagagc tggagtacga gcccaagggc gggctcgtca
     5281 tcgcccccga cgaggccgcg ctgaaggccc tgcgcgcctt cgccgagggg cagcgcgccg
     5341 ccggtgtgga ggccgtcgag gccgacccgg ccgagctgcg cgaactggag ccgcacctgg
     5401 cacccggccg ggcgggcggc ttcctctacc cccaggacgc ccaggtccag cccgcgcagg
     5461 cggccgcccg cctgctcgcc gcctccggcg ccgaactcca cctcggcgag gaggccgtcg
     5521 aggtcgtcac ggccggcggc gccgtccgcg gggtgcgcac cgcgcgacgc gaactcgccg
     5581 cccccgccgt cgtcaacgcc gccggcacct ggggcggccg catcgcggaa ctcgccggca
     5641 cctccctgcc ggtcctgccg cggcgcggct tcgtcctcgt caccgagccg ctgccccggg
     5701 tcgtacggca caaggtgtac gccgccgact acatcgcgga cgtcgcgagc ggctccgcgg
     5761 ccctgcagtc ctcggcggtc gtcgagggca ccccggccgg gccggtgctg atcggggcga
     5821 cccgggagcg cgtcggcttc gaccggtcgc tgtccccgga ggccctgcgc cgcctcgccg
     5881 gccaggccgc cgccctcttc ccggccctcg ctgacgcccg catcctgcgc gcctaccacg
     5941 gcttccgccc ctacctcccc gaccacctcc ccgcgatcgg gcccgacccc cgggtccccg
     6001 gactggtcca cgcctgcggg cacgagggcg ccggcatcgg cctggccccc gccaccgggg
     6061 tgctcgtcgc cgccgccctc accggcgccg aacccccgct cccgctccac cccttccgcc
     6121 cggaccgctt cccggagccc gcggcgcagc cgaaggagac cggccgatga ccgacccctc
     6181 gcaccgccgg tccccgcgcg acctcgtcgg cgggcgcccg gacgcgacgt acaccctgcg
     6241 cttcgacggg cgcgagctga ccgcccacgc ggggcagagc atcgccgccg tgctgtgggg
     6301 cgccggcatc ctcgcctggc gcaccacccg gcagggcggc gccccgcgcg gcgcgttctg
     6361 cgggatcggc agctgctacg actgcctcgt caccgtcaac ggccgcccca accagcgcgc
     6421 ctgcctggtc cccgcccgcc ccggggacgc cgtcaccacc caggaaggga ccggccgtgc
     6481 cgacctcgcc gtctgacctc cccggacccg gcgccccggc cgccgccggc cgcccggacg
     6541 cggcccccgc cgacctcgcc gtcgtcggcg ccggcccggc cggcctcgcc gcggccgtca
     6601 ccgccgcccg gctcggcctg cgcgtcaccc tgctcgacgc gggggagcgg cccggcgggc
     6661 agttctaccg gcaccccgcc ccgcagctgg gcgcggagcg gcccgaggcc ctccaccacg
     6721 gatgggccgc gtttgccgcc cgcgagcggg ccctgcgcgc ccacaccgcc tccggccgcg
     6781 tcacgtacct gcccggccac catgtctgga ccgtggtccg ccgggacgca ccgcaggaca
     6841 ccgctcccgc cggggccgcc cgccgggccc cggccgcctg ggtgctgcac gccgtcgccg
     6901 gacccgagga gcgcgcggtg gccgtacccg cccgcgccgt gctcctggcc accggctcct
     6961 acgagcgcca actgcccttc cccggctgga ccctgcccgg cgtcgtcggc gccggcggcg
     7021 cgcaggccat gctcaaggcc ggcctcgttc tgcccggccg gcgtgtcgtc gtcgccggga
     7081 gcgggccgct gctgctcgcc gtcgccggat ccctcgcctc cgccggggcg cgggtgcccg
     7141 ccgtcgtcga ggccgccgcc tacaccgggt acgcgcccgc cctgcccgcc ctgctgcgca
     7201 accccgccaa gctcgcggag ggcgccgtgt acggcggggc cctgctccgc cacggcgtgc
     7261 ggctgctcac ccggcacgcg gtgaccgagg cgcacggcac cgaccgggtg gaggccgtca
     7321 ccgtggcccg cctggacgcg gactggcggc cgctgcccgg caccgcccgc cgcatcccct
     7381 gcgacgccgt ggccgtcggg cacggcctgg tcccgcagct ggagctggcc accggcctcg
     7441 gctgcgccac ccgccgcgcc gccgacggca ccgccgcgct cgacctcgac gccctccagc
     7501 ggacctccgt acccggcatc tggtccgccg gcgagaccgg gggcatcgcc ggcgcggagc
     7561 cggcgctggt cgagggggag atcgcggccc acgccgtcgc cggccgtccc gtcccggcgg
     7621 ccctggtgcg ccgccgcgcg cggctgcggg ccttcgccga cgcgatgggc cgggtccacc
     7681 ggcccggtga gggctggacc ggatggctgc gggacgacac cgacgtgtgc cggtgcgagg
     7741 aggtgccggc ggggcggatc cgggaggccg tctccgacct cggagcccgg gacgcccgta
     7801 ccgccaaact gctcacccgc gccggaatgg gctggtgcca gggccggatg tgcggaccgg
     7861 ccgtcgccgc cctggccggc gaggagcagg cgcccgaccg gcggccgctg tcctgcccgg
     7921 tgccgctgcg cctgctcgcc ggcctgccgc ccgccgacgg ctgacggccg acggcttgcg
     7981 tccgcgggcg gcgggggccc cggccccctg cgcccccctc ttgccccggc ccgtccggag
     8041 tcttgtggcc gagttcaacc cactagtaaa atgtcacaca ccacacgagg gagctttctc
     8101 atgaccgacg cgcacacccc cgcgcccacc gccgccgacc cgcgcacccg cccctggcac
     8161 ggcatcatgg tcgccaccgc gctgcccatg cgcgaggacc tctccgtcga ctacgacgcc
     8221 tacgccgacc acgtcgcgtg gctcatcgcc aacggctgcg acggcgtcgt ccccaacggc
     8281 tccctcggcg agtaccagac cctcaccgac gaggagcggg cccgcgtcgt gcgcaccgcc
     8341 gtcgaggccg ccggcgacgg cagccgcgtc atgcccggcg tcgccgccta cggcagcgcc
     8401 gaggcccgcc gctgggccga gcaggccgcc gaggccggcg ccggctccgt cctgctgctg
     8461 ccgcccaacg ccttccgcgc cgacgagtcc gccgtccgct cccactacgc cgaggtggcc
     8521 cgcgccggcc tgcccgtcgt cgcgtacaac aacccgatcg acaccaaggt cgacctcacg
     8581 cccgccctgc tggcccggct gcacgccgac ggcagcatcg tcgccgtcaa ggagttcagc
     8641 ggcgacgtcc gccgcgccta cgagatcgcc gaactcgccc ccggcctgga cctcctgatc
     8701 ggcgccgacg acgtcctgct cgaactcgcc ctcgccggcg ccgtcggctg gatcgccggc
     8761 taccccaacg cgctgcccgc cgcctgcgcg accctctacc gggcggccgt cgccggcgac
     8821 ctggacaccg cgctgccgct ctacaagtcc ctgcactcgc tgctgcgctg ggactccaag
     8881 acggagttcg tgcaggccat caagctctcc atggacctcg ccggccgccc gggcggcgcc
     8941 acccgcccgc cccgcttccc gctgaccggg gagaccgagg cggccgtccg cgccgcgacc
     9001 gagaaggccc tcgccgaggg actcaactag ccaaccgggg gaacccatgc gcacgcgcca
     9061 catctaccac gcggtggact cgcacaccga gggcatgccg acccgggtcg tcaccggggg
     9121 cgtcggggtg atccccggcg ccaccatggc cgagaaacgg ctccacttca tcgagcacat
     9181 ggaccacgtc cgcaccctgc tcatgtacga gccgcgcggc cactccgcga tgagcggcgc
     9241 gatcctgcag ccccccaccc gccccgacgc cgacttcggc gtcctctaca tcgaggtgtc
     9301 gggcctgctg cccatgtgcg ggcacggcac catcggggtc gccaccgtcc tcgtcgagac
     9361 gggcatggtg ccggcggtcg agccggtcac caccgtccgc ctcgacaccc ccgccggact
     9421 ggtctccgtc gacgtccgcg tcgaggacgg ggcggccacc gccgtcaccc tcaccaacgt
     9481 ccccgccttc tgcgccggcc tcgacctcaa ggccgacgtc cccggatacg gcaccgtcac
     9541 ctacgacctc gcctacggcg gcaacttcta cgccttcgtc gaactcgacg ccctcggcct
     9601 ccccttcgac cgcgcccgca aggacgacct gctcgccgcc ggactcgccg tcatggacgc
     9661 ggtcaacgcc tccgccgacc ggcccgtcca ccccgaggac cccgccatcg ccggcgtcaa
     9721 gcacgtctac ctcgcggccc ccggctccga cgcccgccgc tcccggcacg ccatggccat
     9781 ccaccccggc tggttcgacc gctcgccctg cggtacgggc accagcgcgc gcatggccca
     9841 gctgcacgcc cgcggcctcc tcggcctcgg cgccgacttc gtgaacgagt ccttcatcgg
     9901 caccgagttc accggccggc tcgtcggccg caccaccgtc ggcgggtacg aggccgtcgt
     9961 gcccgccgtc accgggcggg cctggatcac cggcaccgcc cagtacttcc tcgacccgtc
    10021 cgaccccttc cccggagggt tcctcctgtg accgccgacg accccgccgc gcctgaggtg
    10081 cgcaccgccg actaccacgc ggccggagag ccgttccgga tcgtcgacac cgccgacccc
    10141 ggcctcccgc ccgcccccgg cgacaccgtc gccgagcgct gcgccaccgc gatcggcccc
    10201 ggcggctccg gcaccgcgcc gaggcccggc gcgctggact ccgtacggcg cctgctcgtg
    10261 caggagccgc gcggccacgc cgggatgtac ggcgggttcg tcgtgccccc ggacgacgac
    10321 ggcgcccact tcggcgtcct cttctggcac aaggacggct actccacggc ctgcggccac
    10381 ggcaccatgg cgctgggcgc ctgggccgtg gacaccggcc gggtgcccgc ccccgacgag
    10441 ggcgacgtcc cggtgcggat cgacgtgccg tcgggccggg tcgccgccac cgtccaccgc
    10501 agcggcggcc gcaccaccgg cgtcaccttc cgcaacgtcg cggcccgggt gggcgcccgg
    10561 aaggtccccg tcgccaccag cctcggcctc gccgaggccg acatcgccca cgccggcgcc
    10621 tgctacgcct ccgtccgggc gcgcgacctc ggcctggacg tctcccgggc ctcgctcggg
    10681 gacctggtgc gcgccggccg cgagatccgc accgcgctcg ccgcgcaccc cgccacctgg
    10741 cacccggacg ggccgctgct ctccggcgtc tacggggtga tcttccacga ggagctcccc
    10801 gacaccccct tcggcccgca ccagcgcaac gtcaccgtct tcgccgacgg acaggtggac
    10861 cgctcgccct gcggatccgg cacgtccgcg cggctcgccc tcctcgccga ggacggccgc
    10921 ctcggaccgg aggactccct gctgcacgag tcggtggccg ggacggtgtt caccggccgg
    10981 atcgcccccg cggccgccgc gcccggggag gctccggacg gcctggtcac cgaggtcacc
    11041 ggcagcgcgt accgcaccgg cgagcaccgc ttcacgctcg acccgcacga cgcgctcggc
    11101 gccggcttcc tgctgtgatc cggcagatcg gcgccgccga gatcaccgcg ctgctcgggc
    11161 ccgccgcggc ggccgacgcc ctggccgacg ccctgcgcgc ggggctcgac ccggaggcct
    11221 gcccgcagcg cagcgcggtc gccgtgccgg gcggcgggga actgctgctg atgccggccg
    11281 cgcagggggc gtacgccggt gtgaagatcg ccggggtggc gccgggaaac ccggcgcgcg
    11341 gcctgccccg gatcaccggc tcctacctcc tcctcgacgg gcccaccctc agcccggtcg
    11401 ccctcctcga cggcgccgcc ctcacggcgc tgcgcacacc ggcggtctcg gcgctggccc
    11461 tgcggcacct cgccccggcc gggcggccgc tgcggctggt gctcttcggg acgggcccgc
    11521 aggcgtacgg gcacctcgaa gccgcggccg cggtgcggga gctggccgag gccgtcgtcg
    11581 tgggccggga ccccggcggt ccgggcgcga aggcccttgc ggagcacgcc cgcacactgg
    11641 gcgtcccggc gcggacgggc agcgcggcgg acgtggccgg ggcggacctg gtgctgtgct
    11701 gcaccacggc ccgcaccccg ctcttcgacg ggcggctcgt cgcgcccggc gcggtggtcg
    11761 tggcggtcgg ctcgcacgag ccggacgccc gcgagacgga cacggcgctg gtgcggcgct
    11821 ctgccgtgta cgtcgaagcc cggtcggcgg ccctgcggga ggcgggggac ctgctggttc
    11881 cggaggcgga gggggcgatc gggcccggct gcatcacggc caccctggcc gacctggtcg
    11941 cggggcgggc gccggggccg ggcccggcgg gttgtccaca gctcttcaag agcgtgggca
    12001 tggcctggga ggatctcgcc gtggcggtgg cgctgtacgc ggccgccggg aagaacagcg
    12061 aaacgtgaca ttgtacgctg ttcctctgcg atctctcgga ggacaagcaa tgggtgacct
    12121 gaagcagcac agcctcatca aggcccagga acggctccgc gaccaggtcg gccacgcgct
    12181 ccgagcggct ctgatagcgg gcgaactgcg ccccggcagc gtctactcgg cccccggcct
    12241 cgccgccgaa ctcggcgtct ccgccacccc cgtccgcgag gccatgctcg acctcgcccg
    12301 cgagggcctg gtcgagccgg tccgcaacaa gggcttcagg atcaccgagg tcagcgaacg
    12361 cgacctggac cagtacaccg aactccgcac gatgatcgag gtccccacgg tcggcagggt
    12421 cacccggatg gccgcccgcg agcagctgga ggccctgcgc ccgatcgcgg aggagatcgt
    12481 caccagcgcc cgcgagcaca acctcatcgg ctacctggag gcggaccgcc gcttccacct
    12541 gaccctgctg gggctcgccg ggaacgagcg cctggtcgag accgtcggcg acctgcgcaa
    12601 gcgctcccgc ctctacgggc tcacgggcct ggacgaggcg ggcaagctgg tctcctccgc
    12661 cgaggagcac ctggaactcc tcgacctgat gatcgcgggc gacgcggagg cggccgaggc
    12721 gtgcatggcg cgccacctgg gccacgtccg ctcgctgtgg gcggagggcc gcgacgagcc
    12781 ggtgggccgc cccgcggcgg gcggcctcgg ctccggcctc accggctgaa tgccgcggcc
    12841 gcccggccgg ccgcccgttc ggcccgggcc cgggcccgcc cggctcggcc ggctcagccg
    12901 ccgagcagcc cgagcagcgc gctgaccgcc tcgaccacgg gctgcccgat cgccccgacg
    12961 gtcg
//
