LOCUS       NZ_QOIM01000065         5190 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces reniochalinae strain LHW50302
            NODE_39_length_5190_cov_17.3131_ID_77, whole genome shotgun
            sequence.
ACCESSION   NZ_QOIM01000065
VERSION     NZ_QOIM01000065.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces reniochalinae
  ORGANISM  Streptomyces reniochalinae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 5190)
  AUTHORS   Li,L.
  TITLE     Streptomyces reniochalinae sp. nov. and Streptomyces diacarnus sp.
            nov. from marine sponges
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5190)
  AUTHORS   Li,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUN-2018) Department of Pharmacy, Ren Ji Hospital
            School of Medicine, Shanghai Jiao Tong University, Pujian, Pudong,
            Shanghai 200127, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-FEB-2016
            Assembly Method                   :: A5-misseq v. MARCH-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003323735.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 01:54:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,751
            CDSs (total)                      :: 6,669
            Genes (coding)                    :: 6,475
            CDSs (with protein)               :: 6,475
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 4, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 66 of 194
            Pseudo Genes (incomplete)         :: 154 of 194
            Pseudo Genes (internal stop)      :: 16 of 194
            Pseudo Genes (multiple problems)  :: 41 of 194
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:03:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 5190
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QOIM01000065.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            <1..2869
                     /locus_tag="DQ392_RS33900"
                     /old_locus_tag="DQ392_33880"
     source          1..5190
                     /collected_by="Lei Li"
                     /collection_date="2015-04-30"
                     /country="China: Xisha"
                     /culture_collection="CCTCC:AA 2018013"
                     /culture_collection="DSM:106194"
                     /db_xref="taxon:2250578"
                     /identified_by="Lei Li"
                     /isolation_source="marine sponge"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces reniochalinae"
                     /strain="LHW50302"
                     /submitter_seqid="NODE_39_length_5190_cov_17.3131_ID_77"
                     /type_material="type strain of Streptomyces reniochalinae"
     region          1..5190
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..5190
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..5190
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2914:>5190](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2915..>5190
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     CDS             <3..2869
                     /NRPS_PKS="Domain: PKS_DH (30-202). E-value: 3.1e-44.
                     Score: 143.2. Matches aSDomain:
                     nrpspksdomains_DQ392_RS33900_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (519-697). E-value: 1.3e-59.
                     Score: 193.1. Matches aSDomain:
                     nrpspksdomains_DQ392_RS33900_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (787-871). E-value: 5e-33. Score:
                     105.3. Matches aSDomain:
                     nrpspksdomains_DQ392_RS33900_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (882-954). E-value:
                     2.3e-11. Score: 36.3. Matches aSDomain:
                     nrpspksdomains_DQ392_RS33900_PKS_Docking_Cterm.1"
                     /codon_start=2
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF020243.4"
                     /locus_tag="DQ392_RS33900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_33880"
                     /product="type I polyketide synthase"
                     /protein_id="WP_114019541.1"
                     /sec_met_domain="adh_short (E-value: 2.4e-63, bitscore:
                     200.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.8e-18, bitscore:
                     53.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPTYPFTHHTYWLQQPTPTNTTNLGLNPTHHRFLSAAIDAPDERA
                     MFFSGCLVLDDHPWLREYAIEDSVVLPATAFVELALHAGREVGLSVLDEMEFGAPLVMS
                     EDASVQLRVGVRQQEVPGRYRFTVHTRPSTDGTESPSDGEWVLHASGVLLSGDVSGTAR
                     PVPFNGELPASGVVPVDVGELYEELVRAGFSHGPSFQGVREVWRHGEDVYADVDLPEDV
                     TGAGFALHPALLDSVLHPLLVEAVRAEGGDECVLVPEALSGLALHATGASAVRARLRVT
                     GPRTASVSVVDAEGGPVADVDQLRWRPLRRGELRDSVRRDALFHVEWHRVHSSAARQGD
                     WVVLGDSPLLKTSEPAASYGSLDELRAAVDTGTPVPSCVLVACDGSGGEDSDAARGARV
                     VTRETLGLLQDWLTDDRFTASRLVVVTRGGVAHTAQDDVTDLGGAAVWGLLRSAQSEEP
                     DRFLLVDLDESETSATALSTALAVGEPQLALRGGELFAPRLARTSAAVAGPEAPQPPLD
                     PDGTVLISGGTGELGGAVARHLVREHGARHLLLLSRRGLTDATSVVRDELTALGAQVTV
                     EACDTSDEAALADVLKRVPDEHPLTMVVHAAGVLDDATLLSLTPQSVETVMRAKADSAW
                     KLHRATEEADLSSFVMFSSLAGTLGNAGQANYAAANAFLDALAHHRRARGLPAVSLGWG
                     LWEQQSGMAAELGVPGEERLARVGVEPLPAELGLALFDAAVGGDVRPALVPADLNMTTL
                     RAHAMAGALPRMLGDLVRVPARRGGVGEPDLAGRLAALPESERDALVLELVRGEVASVL
                     RYPSDRAVAADRAFRDLGFDSLTAVELRNRLHAATGVRVPTTVVFDHPTPHALARYLRG
                     AVLPDETTAPTPGLAELEALEAVLRERPPSGGSHDKLTKRLQALLWQLGDSAPLRGGEP
                     EEDVLTATASDEELFKTLDDELGRF"
     aSDomain        95..610
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS33900_PKS_DH.1"
                     /evalue="3.10E-44"
                     /label="DQ392_RS33900_PKS_DH.1"
                     /locus_tag="DQ392_RS33900"
                     /protein_end="202"
                     /protein_start="30"
                     /score="143.2"
                     /tool="antismash"
                     /translation="HRFLSAAIDAPDERAMFFSGCLVLDDHPWLREYAIEDSVVLPATA
                     FVELALHAGREVGLSVLDEMEFGAPLVMSEDASVQLRVGVRQQEVPGRYRFTVHTRPST
                     DGTESPSDGEWVLHASGVLLSGDVSGTARPVPFNGELPASGVVPVDVGELYEELVRAGF
                     SHGPSFQGV"
     aSModule        95..2617
                     /domains="nrpspksdomains_DQ392_RS33900_PKS_DH.1"
                     /domains="nrpspksdomains_DQ392_RS33900_PKS_KR.1"
                     /domains="nrpspksdomains_DQ392_RS33900_PKS_PP.1"
                     /incomplete
                     /locus_tags="DQ392_RS33900"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       179..253
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS33900_0001"
                     /evalue="1.30E-05"
                     /label="PKSI-DH_m2"
                     /locus_tag="DQ392_RS33900"
                     /protein_end="83"
                     /protein_start="58"
                     /score="17.8"
                     /tool="antismash"
                     /translation="WLREYAIEDSVVLPATAFVELALHA"
     aSDomain        1562..2095
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS33900_PKS_KR.1"
                     /evalue="1.30E-59"
                     /label="DQ392_RS33900_PKS_KR.1"
                     /locus_tag="DQ392_RS33900"
                     /protein_end="697"
                     /protein_start="519"
                     /score="193.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLISGGTGELGGAVARHLVREHGARHLLLLSRRGLTDATSVVR
                     DELTALGAQVTVEACDTSDEAALADVLKRVPDEHPLTMVVHAAGVLDDATLLSLTPQSV
                     ETVMRAKADSAWKLHRATEEADLSSFVMFSSLAGTLGNAGQANYAAANAFLDALAHHRR
                     ARGLPAVSLGWGLWE"
     CDS_motif       1565..1666
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS33900_0002"
                     /evalue="5.20E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="DQ392_RS33900"
                     /protein_end="554"
                     /protein_start="520"
                     /score="35.1"
                     /tool="antismash"
                     /translation="TVLISGGTGELGGAVARHLVREHGARHLLLLSRR"
     CDS_motif       1949..2050
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS33900_0003"
                     /evalue="3.50E-22"
                     /label="PKSI-KR_m4"
                     /locus_tag="DQ392_RS33900"
                     /protein_end="682"
                     /protein_start="648"
                     /score="71.0"
                     /tool="antismash"
                     /translation="FVMFSSLAGTLGNAGQANYAAANAFLDALAHHRR"
     aSDomain        2366..2617
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS33900_PKS_PP.1"
                     /evalue="5.00E-33"
                     /label="DQ392_RS33900_PKS_PP.1"
                     /locus_tag="DQ392_RS33900"
                     /protein_end="871"
                     /protein_start="787"
                     /score="105.3"
                     /tool="antismash"
                     /translation="LAALPESERDALVLELVRGEVASVLRYPSDRAVAADRAFRDLGFD
                     SLTAVELRNRLHAATGVRVPTTVVFDHPTPHALARYLRG"
     aSDomain        2651..2866
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS33900_PKS_Docking_Cterm.
                     1"
                     /evalue="2.30E-11"
                     /label="DQ392_RS33900_PKS_Docking_Cterm.1"
                     /locus_tag="DQ392_RS33900"
                     /protein_end="954"
                     /protein_start="882"
                     /score="36.3"
                     /tool="antismash"
                     /translation="PGLAELEALEAVLRERPPSGGSHDKLTKRLQALLWQLGDSAPLRG
                     GEPEEDVLTATASDEELFKTLDDELGR"
     misc_feature    complement(2910..2923)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            2915..>5190
                     /locus_tag="DQ392_RS33905"
                     /old_locus_tag="DQ392_33885"
     CDS             2915..>5190
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (2-30). E-value:
                     1.1e-12. Score: 39.3. Matches aSDomain:
                     nrpspksdomains_DQ392_RS33905_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (34-459). E-value:
                     2.3e-185. Score: 608.5. Matches aSDomain:
                     nrpspksdomains_DQ392_RS33905_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (569-758). E-value: 1.4e-65.
                     Score: 213.5. Matches aSDomain:
                     nrpspksdomains_DQ392_RS33905_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009717845.1"
                     /locus_tag="DQ392_RS33905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_33885"
                     /product="type I polyketide synthase"
                     /protein_id="WP_114019542.1"
                     /sec_met_domain="mod_KS (E-value: 2.2e-230, bitscore:
                     751.8, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.2e-95, bitscore:
                     307.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.7e-67, bitscore: 213.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDDKLREYLRRATTDLRRAHRRLRDVEERAHEPIAIVSMGCRFP
                     GGVESAEGFWTLLREGRDAVSEFPAARGWDIDRLYDADPDRLGHTYTRNGSFIEGAGGF
                     DAEFFGISPREALAMDPQQRLLLETAWHAVELSGVLPATLRGSNTGVFVGTNGQDYTRT
                     LSGVLESVEGHLATGTSASTVSGRISYTFGFEGPAVTIDTACSSSLTAMHLAAHALRNG
                     ECELALAGGVTVMSTPAPFVEFSRQRGLSPDGRCRAFAASADGTAWGEGVGLLVLERLS
                     DAQRNGHPVLAVIRGSAVNQDGASNGLTAPNGPSQERVIRAALANARLSEADVDVVEAH
                     GTGTTLGDPIEAQALLATYGQDRPDDRPLWLGSVKSNIGHTQAAAGVAGVIKMVEAMRH
                     GLLPRTLHVDEPTPHVDWSTGAVRLLTETTAWPETGRPRRAAVSSFGISGTNAHLILEA
                     WPVTDVAAEDASASAEPAGRVAFTLSAKSQVALRAQAARLEEHLRTRPDLGAWAVAGAL
                     TTTRTVFDHRAVVTGTDRDELIEGLRALAQDETRPGVVCPGQAADASGRTAFLFSGQGS
                     QRAGAGAGLYAAEPVFKAAVDEACQHLDPLLGRSLVEVMCAEPGSEAARLLDHTYYTQP
                     ALFALHLGLHRLLEHHGLKPDVLAGHSVGEISAAHCAGVFSLADAARLIVKRAELMGQL
                     PPGAMASIQATADELTPHLSDQVCVAAYNTPRHTVISGDPDAVAAIVEAFTAQGRRVKT
                     LATEHG"
     aSDomain        2921..3004
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS33905_PKS_Docking_Nterm.
                     1"
                     /evalue="1.10E-12"
                     /label="DQ392_RS33905_PKS_Docking_Nterm.1"
                     /locus_tag="DQ392_RS33905"
                     /protein_end="30"
                     /protein_start="2"
                     /score="39.3"
                     /tool="antismash"
                     /translation="DDKLREYLRRATTDLRRAHRRLRDVEER"
     aSDomain        3017..4291
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS33905_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.30E-185"
                     /label="DQ392_RS33905_PKS_KS.1"
                     /locus_tag="DQ392_RS33905"
                     /protein_end="459"
                     /protein_start="34"
                     /score="608.5"
                     /tool="antismash"
                     /translation="IAIVSMGCRFPGGVESAEGFWTLLREGRDAVSEFPAARGWDIDRL
                     YDADPDRLGHTYTRNGSFIEGAGGFDAEFFGISPREALAMDPQQRLLLETAWHAVELSG
                     VLPATLRGSNTGVFVGTNGQDYTRTLSGVLESVEGHLATGTSASTVSGRISYTFGFEGP
                     AVTIDTACSSSLTAMHLAAHALRNGECELALAGGVTVMSTPAPFVEFSRQRGLSPDGRC
                     RAFAASADGTAWGEGVGLLVLERLSDAQRNGHPVLAVIRGSAVNQDGASNGLTAPNGPS
                     QERVIRAALANARLSEADVDVVEAHGTGTTLGDPIEAQALLATYGQDRPDDRPLWLGSV
                     KSNIGHTQAAAGVAGVIKMVEAMRHGLLPRTLHVDEPTPHVDWSTGAVRLLTETTAWPE
                     TGRPRRAAVSSFGISGTNAHLILEAW"
     aSModule        3017..5188
                     /domains="nrpspksdomains_DQ392_RS33905_PKS_KS.1"
                     /domains="nrpspksdomains_DQ392_RS33905_PKS_AT.1"
                     /incomplete
                     /locus_tags="DQ392_RS33905"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       3425..3481
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS33905_0001"
                     /evalue="5.40E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="DQ392_RS33905"
                     /protein_end="189"
                     /protein_start="170"
                     /score="-2.8"
                     /tool="antismash"
                     /translation="VEGHLATGTSASTVSGRIS"
     CDS_motif       3500..3547
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS33905_0002"
                     /evalue="8.40E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="DQ392_RS33905"
                     /protein_end="211"
                     /protein_start="195"
                     /score="20.8"
                     /tool="antismash"
                     /translation="GPAVTIDTACSSSLTA"
     CDS_motif       3842..3862
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS33905_0003"
                     /evalue="8.70E+01"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="DQ392_RS33905"
                     /protein_end="316"
                     /protein_start="309"
                     /score="-2.7"
                     /tool="antismash"
                     /translation="APNGPSQ"
     CDS_motif       3923..3967
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS33905_0004"
                     /evalue="1.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="DQ392_RS33905"
                     /protein_end="351"
                     /protein_start="336"
                     /score="13.9"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       4028..4072
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS33905_0005"
                     /evalue="2.30E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="DQ392_RS33905"
                     /protein_end="386"
                     /protein_start="371"
                     /score="13.4"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       4619..4672
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS33905_0006"
                     /evalue="5.50E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="DQ392_RS33905"
                     /protein_end="586"
                     /protein_start="568"
                     /score="12.7"
                     /tool="antismash"
                     /translation="FLFSGQGSQRAGAGAGLY"
     aSDomain        4622..5188
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS33905_PKS_AT.1"
                     /evalue="1.40E-65"
                     /label="DQ392_RS33905_PKS_AT.1"
                     /locus_tag="DQ392_RS33905"
                     /protein_end="758"
                     /protein_start="569"
                     /score="213.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFSGQGSQRAGAGAGLYAAEPVFKAAVDEACQHLDPLLGRSLVEV
                     MCAEPGSEAARLLDHTYYTQPALFALHLGLHRLLEHHGLKPDVLAGHSVGEISAAHCAG
                     VFSLADAARLIVKRAELMGQLPPGAMASIQATADELTPHLSDQVCVAAYNTPRHTVISG
                     DPDAVAAIVEAFTAQGRRVKTLATEH"
     CDS_motif       4868..4987
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS33905_0007"
                     /evalue="5.80E-21"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="DQ392_RS33905"
                     /protein_end="691"
                     /protein_start="651"
                     /score="66.7"
                     /tool="antismash"
                     /translation="GLKPDVLAGHSVGEISAAHCAGVFSLADAARLIVKRAELM"
     CDS_motif       5072..5110
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS33905_0008"
                     /evalue="1.80E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="DQ392_RS33905"
                     /protein_end="732"
                     /protein_start="719"
                     /score="14.7"
                     /tool="antismash"
                     /translation="AAYNTPRHTVISG"
     CDS_motif       5144..5170
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS33905_0009"
                     /evalue="9.90E+01"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="DQ392_RS33905"
                     /protein_end="752"
                     /protein_start="743"
                     /score="-3.5"
                     /tool="antismash"
                     /translation="FTAQGRRVK"
ORIGIN
        1 cctccccacc taccccttca cccaccacac ctactggctc caacaaccca cccccaccaa
       61 caccaccaac ctcggactca accccacaca ccaccgcttc ctcagtgctg cgatcgacgc
      121 gccggatgag cgagcgatgt tcttttccgg ttgcctggtc ctggacgacc atccctggct
      181 cagggagtac gcgatcgagg actcggtcgt cctgcctgcg accgccttcg tcgagctcgc
      241 tctgcacgcc ggccgggaag tggggctgag cgtcctggac gagatggagt tcggcgctcc
      301 tctggtgatg tcggaggacg cgtccgtgca actgcgtgtg ggggtcaggc agcaggaggt
      361 gcccgggcgg taccgcttca ccgtgcacac gcgtcccagt acggacggga ccgagagccc
      421 ctccgacggg gagtgggtgc tgcacgcgtc cggtgtgttg ttgtccggcg acgtttccgg
      481 cacggcgcgc cccgtgccgt tcaacggcga gttgcccgcg tccggagtgg tgccggtcga
      541 tgtgggcgag ctctatgagg agctggtgcg ggccggtttc agtcacggcc cgtccttcca
      601 gggggtacgc gaggtctggc ggcacggtga ggacgtgtac gccgacgtcg atctgcccga
      661 ggacgtcacc ggtgccgggt tcgcgcttca tccggcgctg ctcgacagcg tgctgcatcc
      721 gctgttggtc gaggcggtgc gggcggaggg cggcgacgag tgcgttctcg tgccggaggc
      781 gctgtccggt ctggccctcc acgcgacggg ggcttccgcg gtacgtgccc ggctgcgggt
      841 gacgggcccc cgtacggcgt cggtctcggt cgtggacgcc gaaggcggcc cggtcgccga
      901 cgtcgaccag ctgcgctggc gaccgctgcg ccgcggtgaa ctgcgggact cggtgcgccg
      961 agatgctctg ttccacgtgg agtggcaccg tgtccactcg tccgcggcgc gtcagggcga
     1021 ctgggtggtg ctgggtgaca gccctctcct caagacgagc gaacccgcgg cgtcgtacgg
     1081 gtcactcgac gagctgcgag cggcggtcga caccggcact ccggtgccgt cgtgcgtact
     1141 cgtggcgtgc gacggcagcg gcggcgagga ctccgacgcg gcccgcgggg cacgcgtcgt
     1201 cacacgggag acgctgggcc tgctgcaaga ctggctgacg gacgaccggt tcaccgcgtc
     1261 gcgactcgtc gtcgtgaccc ggggcggtgt ggcgcacacg gcgcaggacg acgtgaccga
     1321 cctgggcggt gccgcggtat gggggttgct gcgctccgcg cagagtgagg agcccgaccg
     1381 gttcctgctc gtcgacctcg acgagtccga gacctccgcc acggcccttt ccacggcact
     1441 ggcggtgggt gagccgcagc tggcgctgcg cgggggcgag ttgttcgcgc ctcggctggc
     1501 gcgcacgtcc gccgcggttg ccggccctga ggcgccgcag ccgcccctcg acccggacgg
     1561 caccgttctc atcagcggcg gcaccggaga gctcggcggg gcggtcgccc ggcacttggt
     1621 gcgcgagcac ggggcgcgac atctcctcct cctcagccgg cgcggcctca ccgacgcgac
     1681 ctcggtggtg agggacgagc tgacggccct cggcgcgcag gtcaccgtcg aggcgtgcga
     1741 cacgagcgac gaggctgcgc tcgcggacgt gctgaagcgc gttccggacg agcatccact
     1801 gacgatggtc gtccacgcgg ccggggtcct cgacgacgcg acactgctca gcctgacgcc
     1861 gcagagcgtc gagaccgtca tgcgtgcgaa ggccgacagc gcctggaagc tgcaccgggc
     1921 gaccgaagag gcggacctct cgtccttcgt gatgttctcg tccctcgcgg gcaccctcgg
     1981 caacgcaggg caggccaact acgcggcggc gaacgcgttc ttggacgccc tggcccacca
     2041 ccgccgcgcg aggggtctgc ccgcggtctc cctcggctgg gggctgtggg agcaacagag
     2101 cgggatggcc gcggagctcg gggttccggg tgaggagcgc cttgcccgcg tcggcgtcga
     2161 gccgcttccc gccgagctgg ggctcgccct gttcgacgcg gctgtgggcg gcgacgtccg
     2221 ccccgccctg gtaccggccg acttgaacat gacgactctg cgcgcgcacg cgatggcggg
     2281 tgctctgccc cggatgctcg gggacctggt acgagtgccg gcacgccggg gcggcgtcgg
     2341 tgaaccggac ctggcgggac gcctggccgc gcttcccgag tccgagcggg acgctctcgt
     2401 gctggagctg gtacggggcg aggtcgcctc ggtgctcagg tatccgtcag accgggcggt
     2461 cgccgcggac cgggccttcc gcgacctggg gttcgactcg ctcacggccg tcgaactgcg
     2521 caacagactg cacgccgcga cgggcgtacg ggtgcccacg acggtcgtct tcgaccaccc
     2581 cacgccccac gccctcgccc gctacctgcg cggcgcggtg ctccccgacg agaccaccgc
     2641 gccgacgccc ggcctggccg agctggaggc gctggaggcg gtgttgcggg aacgtccgcc
     2701 gtccggcggg tcacacgaca agctcaccaa gcggctccag gccctgctgt ggcagctcgg
     2761 tgactccgcc ccgctgcgcg gcggcgagcc cgaagaggac gttctcaccg cgacggcgag
     2821 cgacgaagag ctcttcaaga cgctcgacga cgagttggga cgtttctgag gtgacgacgc
     2881 ctgatgacat ccggacccag ggggaggcgg cacggtgagt gacgacaaac tgcgagagta
     2941 cctccggcgc gccaccactg atctgcgccg ggcccaccgc cgtctgcggg acgtcgagga
     3001 gagggcgcac gagccgatcg cgatcgtctc catgggctgc cgcttcccgg gtggtgtcga
     3061 gtccgctgaa ggcttctgga cgttgctgcg agaaggccgg gacgcggtct cggagttccc
     3121 cgccgcacgc ggctgggaca tcgacaggct gtacgacgcc gaccccgacc ggctcggaca
     3181 cacctacacc cgcaacggct cgttcatcga gggcgccggc ggtttcgacg cggagttctt
     3241 cggtatcagc ccgcgcgagg cgttggcgat ggacccgcag cagcggctgc tgctggagac
     3301 ggcctggcac gccgtcgaac tgagcggcgt cctcccggcc accctgcggg gcagcaacac
     3361 gggagtcttc gtcggaacca acggccagga ctacacacga accctgtccg gcgtcctgga
     3421 aagcgtcgaa ggccacctcg ccacgggcac ctcggcgagc accgtctccg ggcggatctc
     3481 ctacaccttc gggttcgagg gcccggcggt cacgatcgac acggcgtgct cgtcgtcgct
     3541 gaccgccatg cacctggccg cgcacgcact gcgcaacggc gagtgcgagc tcgccctggc
     3601 gggcggcgtc acggtgatgt ccacacccgc accgttcgtg gagttcagcc gccagcgcgg
     3661 actgtctccg gacgggcgct gccgcgcctt cgccgcctcg gcggacggca ccgcgtgggg
     3721 cgagggcgtg ggactgctgg tacttgagcg actgtcggac gcccagcgca acggccaccc
     3781 ggtactggcc gtcatccggg gcagcgcggt caaccaggac ggcgcgagca acggtctgac
     3841 ggctccgaat ggtccgtcgc aggagcgggt gattcgtgcg gcgctggcga acgcgcggct
     3901 gagcgaggcc gatgtcgatg tggtggaggc gcacggtacg ggcaccacgt tgggtgatcc
     3961 gatcgaggcg caggcgctgt tggcgacgta tgggcaggac cggcccgacg atcggccgtt
     4021 gtggttgggg tcggtgaagt cgaacatcgg tcatacgcag gctgctgcgg gtgtggcggg
     4081 tgtgatcaag atggtcgagg cgatgcggca cggtctgctg ccgcgcacac tgcacgtgga
     4141 cgagcccacc ccgcacgtcg actggtcgac gggcgcggtg cgactgctga ccgagacgac
     4201 cgcgtggccg gagaccgggc gtccgcggcg ggctgcggtc tcctcgttcg ggatcagcgg
     4261 gacgaatgcc catctgattc tcgaagcttg gcctgtcacg gacgttgcag ctgaggatgc
     4321 ctccgcgtct gcggagcccg cagggcgggt ggcgttcacg ctgtcggcga agtcgcaggt
     4381 ggcattgcgg gcccaggcgg cccggctgga ggagcatctg cgcactcgtc ccgacctggg
     4441 ggcgtgggct gttgcggggg cgttgaccac cacacgtacg gtcttcgacc accgcgcggt
     4501 cgtcaccggg acggaccgtg acgagctgat cgagggccta cgcgccctgg cccaggacga
     4561 gacgcgcccc ggtgtggtgt gcccgggtca ggctgccgac gcctccgggc ggacggcgtt
     4621 cctgttctcg gggcagggtt cgcagcgcgc gggggccggc gccgggctgt atgccgctga
     4681 gccggtgttc aaggcggcgg tcgatgaagc ctgccaacac ctcgaccccc tgttgggccg
     4741 gtcgctggtg gaggtcatgt gcgccgagcc gggcagtgag gcggccaggc tgctggacca
     4801 cacctactac acccagcccg cactgttcgc cctccacctg ggcctgcacc gcctcctgga
     4861 acaccacggc ctcaagcccg acgttctggc ggggcactcg gtgggggaga tcagcgctgc
     4921 ccactgcgcg ggagtcttct ccctcgcgga tgccgcacgc ctgatcgtca agcgagcaga
     4981 gctgatgggg cagctgcctc ccggcgcgat ggccagcatc caagccaccg cagacgaact
     5041 caccccccac ctcagtgatc aggtgtgtgt cgcggcctac aacacacccc gccacaccgt
     5101 catctccggc gatccggacg ctgtcgcggc catcgtggag gcgttcacgg ctcaggggcg
     5161 gagggtgaag acactcgcga ccgagcatgg
//
