LOCUS       NZ_QOIM01000038        31075 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces reniochalinae strain LHW50302
            NODE_2_length_500062_cov_17.1742_ID_3, whole genome shotgun
            sequence.
ACCESSION   NZ_QOIM01000038
VERSION     NZ_QOIM01000038.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces reniochalinae
  ORGANISM  Streptomyces reniochalinae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 500062)
  AUTHORS   Li,L.
  TITLE     Streptomyces reniochalinae sp. nov. and Streptomyces diacarnus sp.
            nov. from marine sponges
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 500062)
  AUTHORS   Li,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUN-2018) Department of Pharmacy, Ren Ji Hospital
            School of Medicine, Shanghai Jiao Tong University, Pujian, Pudong,
            Shanghai 200127, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-FEB-2016
            Assembly Method                   :: A5-misseq v. MARCH-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003323735.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 01:54:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,751
            CDSs (total)                      :: 6,669
            Genes (coding)                    :: 6,475
            CDSs (with protein)               :: 6,475
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 4, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 66 of 194
            Pseudo Genes (incomplete)         :: 154 of 194
            Pseudo Genes (internal stop)      :: 16 of 194
            Pseudo Genes (multiple problems)  :: 41 of 194
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:03:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 212310
            Orig. end                         :: 243385
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QOIM01000038.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31075
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /product="hydrogen-cyanide"
                     /region_number="2"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..31075
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-i"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..26103
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26103
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16103](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16103)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(537..550)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(1279..1299)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.24"
                     /tool="antismash"
     misc_feature    1737..1753
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.09"
                     /tool="antismash"
     misc_feature    1743..1756
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.82"
                     /tool="antismash"
     gene            complement(2259..2855)
                     /locus_tag="DQ392_RS20430"
                     /old_locus_tag="DQ392_20405"
     CDS             complement(2259..2855)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1224: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468292.1"
                     /locus_tag="DQ392_RS20430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20405"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_114017089.1"
                     /transl_table=11
                     /translation="MTSVAATRRSRITPEREAELYGAVLQLLREVGYDALTMDAVATAT
                     HSSKATLYRQWGSKPELVARALKHGRPGAARGVADTGSLRGDLRDAIVHAFDDCRIEQD
                     AALMRGVGRAAHDSPELLRALRELLIEPSIADLHVMLDRAVERGEIRSDNPALDFVPHM
                     LVGALISRELIEGLAATQDFLATYLDAVVLPALRA"
     gene            complement(3003..3926)
                     /locus_tag="DQ392_RS20435"
                     /old_locus_tag="DQ392_20410"
     CDS             complement(3003..3926)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (22-235). E-value: 3.9e-36.
                     Score: 116.7. Matches aSDomain:
                     nrpspksdomains_DQ392_RS20435_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_205355621.1"
                     /locus_tag="DQ392_RS20435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20410"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_114017316.1"
                     /sec_met_domain="ADH_N (E-value: 5.8e-11, bitscore: 37.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.1e-11, bitscore:
                     39.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEAIAFATYGDPEVLQPTGIDVPEPDPDQVRIAVRAVGVNPLDW
                     KIRSGAMVTAMPVTLPHIPGLEFAGTVESVGDGVGDLAAGDEVFGRAPSAYASLLLADT
                     ARLRRRPDDLDVRRAAGLPVAAEAAHRALTELQVAAGETVLVHGAGGAVGNLAVQFALE
                     SGAHVVGTAGERERERLTRLGATQVTYGNGWADRVRAAAPGGVAAVLDASGADVLGESV
                     RLVGGPARVLTLADPQAAQSLGVRFSSGAADEERTGEALDRVLALHRRGTLDVPLHEPI
                     PLAGAARAHRAGEAGGLDGKLVLTVR"
     aSDomain        complement(3222..3860)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS20435_PKS_ER.1"
                     /evalue="3.90E-36"
                     /label="DQ392_RS20435_PKS_ER.1"
                     /locus_tag="DQ392_RS20435"
                     /protein_end="235"
                     /protein_start="22"
                     /score="116.7"
                     /tool="antismash"
                     /translation="VPEPDPDQVRIAVRAVGVNPLDWKIRSGAMVTAMPVTLPHIPGLE
                     FAGTVESVGDGVGDLAAGDEVFGRAPSAYASLLLADTARLRRRPDDLDVRRAAGLPVAA
                     EAAHRALTELQVAAGETVLVHGAGGAVGNLAVQFALESGAHVVGTAGERERERLTRLGA
                     TQVTYGNGWADRVRAAAPGGVAAVLDASGADVLGESVRLVGGPARVLTLA"
     CDS_motif       complement(3444..3506)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS20435_0002"
                     /evalue="9.30E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="DQ392_RS20435"
                     /protein_end="161"
                     /protein_start="140"
                     /score="21.4"
                     /tool="antismash"
                     /translation="GETVLVHGAGGAVGNLAVQFA"
     CDS_motif       complement(3699..3734)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS20435_0001"
                     /evalue="2.30E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="DQ392_RS20435"
                     /protein_end="76"
                     /protein_start="64"
                     /score="11.0"
                     /tool="antismash"
                     /translation="GLEFAGTVESVG"
     gene            complement(4008..5558)
                     /locus_tag="DQ392_RS20440"
                     /old_locus_tag="DQ392_20415"
     CDS             complement(4008..5558)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060505.1"
                     /locus_tag="DQ392_RS20440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20415"
                     /product="amino acid permease"
                     /protein_id="WP_114017090.1"
                     /transl_table=11
                     /translation="MRTKSIEATLRDAERPATRLNRTLGPLQLTMMGIGVTIGGGIFVL
                     TGTAAANYAGPAIALSFALGAFVSGLVALCYMEFASTVPVAGSAYTFAYVSLGEPIAWL
                     IGWDLILDMTMGAGAVAAGWSQYVTDFLATFGIRLPEAIAGPEAAVNVPAVAVILVLTA
                     ILAAGVRTTSRLNTAMTLVKLAAIVLFLVVGVSHVDPDNWAPFVPESRPAGAEGGFWEQ
                     PLLGWAGISTNATFGFAGILTGAAIVFGSYSGFDIMASSAEEAKRPQRTLPIALMATVA
                     ACATLYVAVSLVVTGMRPYAQLDNAAPVTGALQAAGEDWAVRVVGVGAICGLTTVVMIM
                     LLGQSRVFLAMSRDRLLPGWFARVHPVTRSPRRITWTLGCMVALMTALLPIQDLAELGN
                     IGMLTSFIAVCVGVIYLRRRRPDLPRAFRTPWVPVLPLVALALCLVLVGSLPLITWARF
                     LAWMAVGVLIYLLWGRRNSRVATGAAETPGGTGTSLPDPADPVTDSVAGEGASREPGR"
     gene            complement(5570..6892)
                     /locus_tag="DQ392_RS20445"
                     /old_locus_tag="DQ392_20420"
     CDS             complement(5570..6892)
                     /NRPS_PKS="Domain: Aminotran_5 (62-380). E-value: 1.7e-30.
                     Score: 98.1. Matches aSDomain:
                     nrpspksdomains_DQ392_RS20445_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008749479.1"
                     /locus_tag="DQ392_RS20445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20420"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_114017091.1"
                     /sec_met_domain="Aminotran_5 (E-value: 2.9e-22, bitscore:
                     73.8, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.1e-06, bitscore:
                     21.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPSTEPGQGAGHPFEDWALDPAVRHLNHGSYGAVPRAALAAQQA
                     LRTEMDAGPDPWFRGLPERVAHARTHIARYLRTPPEDLALVANASAGVSAVLGSITLPP
                     ETEVLLTDHAYGAVVWAVERAARRAGARVRTVHLPLGATAEEITARVGAALAAGPVSLL
                     VVDQITSATARLFPVADLVGVAHSAGARVLVDGAHGPGMLADPLAHAGEADYWVGNLHK
                     WPCTPRGTGALVARGPLAQELYPVVDSWGAPEPFPQRFDHQGTADLTAWLAAPAALEFI
                     ERRYGWDAARARMTQLADAAQHTLAAALGRTEAPAELAACAAPAMRLVPLPAGLAADQE
                     AAHALQRRISARTGCDVACTTWNGRGFLRLSAHLYNDAADYAHLAEQLPACLAECRADT
                     ETTAHPDAPGAHPEAPGVRAADAAHGDAHADASGAGVDAQA"
     aSDomain        complement(5753..6706)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS20445_Aminotran_5.1"
                     /evalue="1.70E-30"
                     /label="DQ392_RS20445_Aminotran_5.1"
                     /locus_tag="DQ392_RS20445"
                     /protein_end="380"
                     /protein_start="62"
                     /score="98.1"
                     /tool="antismash"
                     /translation="ERVAHARTHIARYLRTPPEDLALVANASAGVSAVLGSITLPPETE
                     VLLTDHAYGAVVWAVERAARRAGARVRTVHLPLGATAEEITARVGAALAAGPVSLLVVD
                     QITSATARLFPVADLVGVAHSAGARVLVDGAHGPGMLADPLAHAGEADYWVGNLHKWPC
                     TPRGTGALVARGPLAQELYPVVDSWGAPEPFPQRFDHQGTADLTAWLAAPAALEFIERR
                     YGWDAARARMTQLADAAQHTLAAALGRTEAPAELAACAAPAMRLVPLPAGLAADQEAAH
                     ALQRRISARTGCDVACTTWNGRGFLRLSAHLYNDAAD"
     misc_feature    complement(6912..6926)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.81"
                     /tool="antismash"
     gene            7154..7846
                     /locus_tag="DQ392_RS20450"
                     /old_locus_tag="DQ392_20425"
     CDS             7154..7846
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004929801.1"
                     /locus_tag="DQ392_RS20450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20425"
                     /product="FCD domain-containing protein"
                     /protein_id="WP_114017092.1"
                     /transl_table=11
                     /translation="MAATDTAARGLRAMLGSGELTPGQQLPPEPELCSRLGVSRGSLRE
                     AVRSLAALGMLESRHGSGTYVSALLPAQMLAGFAATVDVLPLDGLLELYDVRRGLESHA
                     AALAAARAEDGVVDRLRALHARLSVTEDDDELHDLDREFHATLCAASGNDTLAALCDIL
                     RSRGRHYSVYGTEETDALRTASDLGHEALIAALAARDPQAAAAAASAHLSQTERWLRRL
                     RPTPGSGR"
     gene            7932..8882
                     /locus_tag="DQ392_RS20455"
                     /old_locus_tag="DQ392_20430"
     CDS             7932..8882
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537613.1"
                     /locus_tag="DQ392_RS20455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20430"
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_114017093.1"
                     /transl_table=11
                     /translation="MPRETGSHCDDALRVVDSAALARALPVGEAVEALRAALRAGLDVA
                     ATPPRSRVPTSTGQLLLMPAEYGEHAGVKIAGVVPGNPARGLPRISGAYLLMDATTLRP
                     TALLDGEALTLLRTSAVSALAADHLAAPDAGRLVVFGTGPQAFAHAVALHQVRPLSAVQ
                     VVGRDPQRVARFAERCEEVGMTASAAAPDAVADADLIACCTSSTAPLFDGRALPAHAAV
                     VAMGSHDPGARELDTRTLTSGTVVVEDAATALREAGDIVIPVQEGALSAASLVPLADVV
                     CGRHPLADGGPRVFKGTGMAWQDLVVAAAAVSGPA"
     gene            complement(8906..9880)
                     /locus_tag="DQ392_RS20460"
                     /old_locus_tag="DQ392_20435"
     CDS             complement(8906..9880)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537126.1"
                     /locus_tag="DQ392_RS20460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20435"
                     /product="urea transporter"
                     /protein_id="WP_114017094.1"
                     /transl_table=11
                     /translation="MSRSVAWDLPEPSGARRQPVRFGYEVLRGIAQVDFMPNAACGLFF
                     VAALFAAGWRYGLAGLLGTALGTATAHALGVDRERTAAGLEGFNGCLVAVAFAVFLGPG
                     HASTWLMAAGGAVVASVLTAALVNLLRPWSIPTFTLPFCLVAGVVTVAAPGFQRVWHEG
                     SSLSALPRSASGDASLGLGDAAHAVLANVGQIFLMPQWYVGLLFLAGIFVADWFAGLTA
                     CLGSVVGTATSWALGAPASDVAEGLLGYNAVLVAMALGAVFLERGVAALVYGVVGAVAS
                     TVLTVAVTSFFAPFGGHTLTWPYVLTTLFFLAAVPSFPRLRRA"
     gene            complement(10001..11530)
                     /locus_tag="DQ392_RS20465"
                     /old_locus_tag="DQ392_20440"
     CDS             complement(10001..11530)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569784.1"
                     /locus_tag="DQ392_RS20465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20440"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_245981703.1"
                     /sec_met_domain="LANC_like (E-value: 6.9e-20, bitscore:
                     65.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQQALTPDTAARRLALRLAVATLGQWTDRARRAAAQRPPDRVRR
                     HTDVAGTADPARRSAQAVPAADAARQPGHAARHSAGDRPAEAAGRVRPADGARRSTAHA
                     GSGPSTPAIASVDHPGDPGVPVLARLVAAMGDAEAAAVAARAAAVWARDAGRGPGHRGL
                     FDGGLAGTLVGLRQCAVLHPALHPVADRLRDRLLDHPARPSAGGAEPPGRPRGAPERYG
                     AVTFPDYDLILGPSGVLLALTADGHEARGTAGEAEYGPAACAAYLSSAARLAALCDGAE
                     LPGLRAHYPAHPVLGWLHGRINTGMGHGVAGVTAALTAAVRQVGPRPELASALRNTSRW
                     LMKESFDDARDIRTWTGCGLDGQARPPGAHARQAWCYGTPGVSWALWDAADALGDPVGA
                     AWAAAAFHTLADGYHEGFHLFGDHPGDRLGLCHGAAGVLAVADAMRRHGRLPAAAALRE
                     RLLRHFVAQEDELWSLAGERCGLLGGAGGALAAVLTATGGNRGWLSCAGLR"
     gene            complement(11827..11988)
                     /locus_tag="DQ392_RS34515"
     CDS             complement(11827..11988)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019546722.1"
                     /locus_tag="DQ392_RS34515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_181856501.1"
                     /transl_table=11
                     /translation="MPVMTEAPELDLDSLIDDLDTRISSTTELPETQLDTAGCSGLCTV
                     LVCTVIVC"
     gene            complement(12008..15109)
                     /locus_tag="DQ392_RS35885"
                     /old_locus_tag="DQ392_20445"
     CDS             complement(12008..15109)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="DQ392_RS35885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20445"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_114017095.1"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 7.6e-08,
                     bitscore: 27.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.3e-14, bitscore:
                     47.9, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPRQRHTDPARATPGPRHSPHASPDHTPARDSASAPLGAAALLR
                     LAGVPGAVWAGAGSPALFAQADELADRRARLVARARALSVRTGEEVVPHEDLTTGDRRA
                     VLALRRRLHAGDAPATDSGEGGTARLPDPTGPAADDDALLDRIAALRPALGRDLRALAA
                     DAAGLRTAYGGFGRAVAAERDRVSAMLLEAARSQPVLRSFVEGAAPRVVADLERRAAAG
                     ELWESKRQRKGVGYLWRALGRAAAKTTPRDWAGQLAVVPVAGRRPVSASPSRRPLVAGG
                     PTGSLPAADPLPGPFAPGTSPECQPSGPAVALLPEFCPGPQLVAARRTENVHRLWCLLR
                     DLDLSAAAPHLLLTPAPLHRATGEPGLGHLHFSVVDPDTGGGGRLRRLSLRRTPALEAV
                     MRLLAATPRTVGSLEAALGPPSSQPALRAFLAHLHTLGILQVCAAPRARRLPWTEHRPG
                     LPVPLAGGLARGSFLDSYRRVTSSRPDVTSSRPEATDPRPEVTDPRPEATAPYPDVTDP
                     RDDGTDPRAEVPDTAARTVADGLALARRVAELCEANRGRGEKRQEVAEAVGLGAEPVSA
                     VRLLEADHADGRPAAPRTRGRYACWEPAHTSDSGYARLLAYLGARLDEEQVDVDAALLD
                     EVGAPPVPAVLQTWPVDCLLRPLPRARARRGGPRGQRGLDVAEHPGTLAVLESASPAGV
                     LDARFAEALGELYGGSPAAGYPNPAGYRDFLAAFERRAGVRFVEVLVPPLTEAAANAVR
                     RPVSTSWCTGDSNTPLYYGNSADPRPAAGGGGVTPLPSVRHLPLDRVTLRVAGGALVAE
                     ADGVRVLPVHHATRTPAPPYDRLLPLLTGAGHPATRRMVRLDGLAGAFPRARHVPRLTV
                     GGLLVVSPAQWRIARAALWRLTDSEADKVAALAALRRAAGLPRFGYLRAHPHTKPLPVD
                     LAALPALQAVERLCQAEPGQDLVFEEALPSPDEPPASGSAQVPAADGSSGATAAQLLVR
                     LPHDGTAEHLAARAHAAWCGAIDLPGVPPSSNGGGTPGRTPHPQ"
     aSDomain        complement(13775..13957)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DQ392_RS35885_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="5.00E-09"
                     /identifier="RREFam001.1"
                     /label="DQ392_RS35885"
                     /locus_tag="DQ392_RS35885"
                     /protein_end="445"
                     /protein_start="384"
                     /score="27.7"
                     /tool="antismash"
                     /translation="LRRLSLRRTPALEAVMRLLAATPRTVGSLEAALGPPSSQPALRAF
                     LAHLHTLGILQVCAAP"
     gene            complement(15084..16103)
                     /locus_tag="DQ392_RS20475"
                     /old_locus_tag="DQ392_20450"
     CDS             complement(15084..16103)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358484.1"
                     /locus_tag="DQ392_RS20475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20450"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_114017096.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.8e-11, bitscore:
                     38.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRFKEAGTRGRTVAAAGAAGFTAGLAAARRAARETAVRGAPRTG
                     AWVQLNLTPERDSHGRALCYAELAALADAFLTEERARNFFFMHKAPGIRARFQAAEPGE
                     AAALRAALLRRTDRWEGLRRRPVCAVYEPEHYLFGGPASMAYVHDLFTLDSLAWLDHHV
                     DHPEGAAPSVGWRQSLLMLREVFDGLGIVGWEHRGVWDAVARQTGRRLRDAAAAVDPAA
                     RERAAAGIVAYWRTPRDEALRAFPEDRRDALARHAEAAHRAAVRWRDGHFEAGGASHGA
                     AGEGCEAGEATVGPRTAAACLTVFHWNRGLLSLARQSLLTEALLHEGRAAHATSAAAH"
     misc_feature    16209..16224
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 24.26"
                     /tool="antismash"
     misc_feature    16227..16238
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.6"
                     /tool="antismash"
     misc_feature    16235..16248
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.33"
                     /tool="antismash"
     gene            complement(16385..17305)
                     /locus_tag="DQ392_RS20480"
                     /old_locus_tag="DQ392_20455"
     CDS             complement(16385..17305)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358486.1"
                     /locus_tag="DQ392_RS20480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20455"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_342774965.1"
                     /transl_table=11
                     /translation="MSESEGPERMERLRADCERCAGLCCVALPFAKSADFAADKPAGKR
                     CGNLTEENRCSIHARLRVSGFTGCSVFDCYGAGQRVTAREGTVSGPRLFAVFRVTRQLH
                     ELLWLLTEAARGGRCPEAEARAAELDALIDGDVAALLAADVEAWRARVGPVLEQVSERA
                     RAGLGGRDLRRGDLTGKQLRKARLRGATLRGALLLAADLRGADLRQVDFLGADLRDADL
                     RGADLSGALFLTQPQLNAAHGDSATRLPDTLARPGHWQDHVSPVPAPARQVRGTARAKD
                     SRDGGARARGGRSRGAGKGGRGRGR"
     gene            complement(17389..18198)
                     /locus_tag="DQ392_RS20485"
                     /old_locus_tag="DQ392_20460"
     CDS             complement(17389..18198)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358487.1"
                     /locus_tag="DQ392_RS20485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20460"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_114017098.1"
                     /transl_table=11
                     /translation="MSESSGPEGAETPVADVAHNARVWNYWLGGKDYYAIDQQVGDHVT
                     SMYPSIREVARADRAFLGHVVRYLAGEAGIRQFLDIGTGLPTVENTHQVAQRVAPSSRI
                     VYVDNDPTVLIHARALLTSSEEGATDYIDADAHHPSAIVDAAADTLDFVDPVAVIMLGI
                     LNFIADTDEASRIVDTLMAAVPSGSYLVLTHPTLELGGEANEEAMRFWNENATPPITAR
                     DRAEVAGFFRGLELLPPGIISCSRWRPGHAADDEKTVAQFGAVARKP"
     cand_cluster    17937..31075
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    17937..31075
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[22936:26075](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      22937..26075
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="2"
     gene            18526..18921
                     /locus_tag="DQ392_RS20490"
                     /old_locus_tag="DQ392_20465"
     CDS             18526..18921
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468363.1"
                     /locus_tag="DQ392_RS20490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20465"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_114017099.1"
                     /transl_table=11
                     /translation="MQSYTIGQAARLLGVSPDTARRWADAGRVTTHRDESGRRLIDGRD
                     LAAFSVELGRHAADEDDVPYTTARNAFAGIVTAVRLGDVAAQVEIQAGPHRLVSLLTRE
                     AVEELGLEVGVQATARVKSTNVHIDTP"
     gene            19013..19882
                     /gene="modA"
                     /locus_tag="DQ392_RS20495"
                     /old_locus_tag="DQ392_20470"
     CDS             19013..19882
                     /GO_component="GO:0009897 - external side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0030973 - molybdate ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="modA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358489.1"
                     /locus_tag="DQ392_RS20495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20470"
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_114017100.1"
                     /transl_table=11
                     /translation="MSSPSSSTPSPSSPPSSPSSPLASPSFPRSLPTHRRSLAALAAVA
                     VLVPLTACGGGGDGKGDEAGEGDRTELTVLAASSLTDVFKAAGKAYEKDHPDTKVTFSF
                     AGSQQLAAQVEQGAPADALVTADTTTMEGLSDETGTPDVIAKNRLVIATGEGNPKKVES
                     LRDLTDKKLKVVLAAPEVPVGRYSKQVLDAQKLKVEPVSRETNVRQVLSKVELGEADAG
                     IVYQTDAATAPKKVDAVKVPDGQNAIASYPAATLKGSQHRKEAAAFVKWLKTPAAQKLL
                     REAGFQKP"
     gene            19879..21987
                     /locus_tag="DQ392_RS20500"
                     /old_locus_tag="DQ392_20475"
     CDS             19879..21987
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1214:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540939.1"
                     /locus_tag="DQ392_RS20500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20475"
                     /product="ABC transporter permease"
                     /protein_id="WP_114017101.1"
                     /transl_table=11
                     /translation="MTRTRNPAGRPRAPLALGLPAVLAVAFLLVPLLGILVRTQWAELG
                     THLGSEGVTEAVKLSLLVSGGALALSLLLGVPLAWLLARIDFPGKALVRSLVLLPMVLP
                     PTVGGVALLLGFGRRGLLGPWLEDTFGVVLPFHTSGAVVAATFVAMPFLVISLEGTLAG
                     LRPSYEETAASLGASPVRVFFTVTLPLVAPGLAAGAALTWARALGEFGATITFAGNLPG
                     TTQTLPLQVYLLLQDQPEAATSVSLLLLVIAMAVLFSLRGRWAGGAGASRTRGGKAGGG
                     AGGLSRLRDRWTRGAEGPEPATDPEAPHTTSGTSTGTGTGTGTGTPEVSAAPGESDATV
                     AHVSPSDADTDTDTDTDRWDLHARLGGFTRLTLDAAPGTTVAVVGPNGAGKTTLLRALL
                     GLTPRAHADLALGGTEVGALPPHRRGVAWVPQDGALFPHLSALANTAYGLRAAGVRRGE
                     ARRLALQWLERLEVGHLAHRRPAQLSGGQAGRVALARALAARPRLLLLDEPLAALDQTT
                     RAHVRHTLRGHLGHFGGVCLLVTHDPVEAVSLADRVLVLEDGRALQDAPPAEVARHPRS
                     PWVARMLGRNALAGTAARDGSLVLEDGGSLVVADPVAEGTQVLAVIAPEAVALHRERPQ
                     GSPRNVWAGTVREVTAVGSRMRVLVTCTGRPDLVAEVTADAVAELGLEDGAAVFAGIKA
                     TEITLVER"
     gene            22145..22777
                     /locus_tag="DQ392_RS20505"
                     /old_locus_tag="DQ392_20480"
     CDS             22145..22777
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358491.1"
                     /locus_tag="DQ392_RS20505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20480"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_220182649.1"
                     /transl_table=11
                     /translation="MSGPEAAERSIRGMLALNLKRARAQRGLSISELSRRSKIGKATLS
                     QLESGTGNPTIETVFSLSRVLEVPISDLLDARPPAGLRVVRAQEVEVLSGEGVDLRPLQ
                     RIESGGGVFEVYDQQVRAGERRDSLGHVGVEHTIVQAGRLGVRVEGHDVELGPGDYVGF
                     DATLPHGYTALDGTVRSVLLLQYRADQRLPPDAPHPVAGGCAPHTEA"
     gene            22937..24142
                     /locus_tag="DQ392_RS20510"
                     /old_locus_tag="DQ392_20485"
     CDS             22937..24142
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358492.1"
                     /locus_tag="DQ392_RS20510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20485"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_114017103.1"
                     /sec_met_domain="DAO (E-value: 1.3e-59, bitscore: 197.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGTRAVVLGAGIIGAACARELALAGAAVTVVDRGGPAAATTSHG
                     EGNVLVSDKGPGPELALAQLSRELWPTVLTQVAERSAEGHRAAQAAEWDPKGGIVVATT
                     SAGAHALARFADSQRSAGVRAEPLAPEALREAEPYVTREHTAAVHYGEDAQVQPAGAAT
                     ALLTDALAAGAALRGGEEVCSGVVRGGRLTGVRTTHGLLEADLFVNAAGPWSGALAARL
                     GAPVGVEPRRGDVLVTTPQPPTVFHKVYDADYVGSVGSGEEESQTSAVVESTRAGSLLI
                     GSSRRRVGFDDRLRPEVLSAVAAKALRLFPSLARVPVMRAYGGFRPYVADHLPVIGADP
                     RLPGLWHASGHEGAGIGLSVGTGRLLLHLVRGEPPPVDAAAFRVDRPAVLRPRQYQQQE
                     TT"
     gene            24139..24486
                     /locus_tag="DQ392_RS20515"
                     /old_locus_tag="DQ392_20490"
     CDS             24139..24486
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016570659.1"
                     /locus_tag="DQ392_RS20515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20490"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_114017104.1"
                     /sec_met_domain="Fer2_4 (E-value: 4.7e-22, bitscore: 72.6,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPRLVPAQRDATGRRDRPLRVTVDGVPADGIAGQTLAGLMLASG
                     RTSWRRAPSGAPRGLFCGIGVCFDCLVTVNGEPDVRACRRRAVDGDEVTTHSRAGHGDA
                     DGPGRTAREER"
     gene            24489..26075
                     /locus_tag="DQ392_RS20520"
                     /old_locus_tag="DQ392_20495"
     CDS             24489..26075
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468369.1"
                     /locus_tag="DQ392_RS20520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20495"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_114017318.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.6e-20, bitscore:
                     68.2, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 2.6e-07, bitscore:
                     25.8, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAARRVAVVGAGPAGLSAAHAALAAGARVTLIDAAEEPGGQYHR
                     TVPETYGPQRPVRLQHGWRAFERRRRRVLAHPRCTWLPRTSVWALEQPQPEHEGPPRLH
                     LLCAGPADGAGRTRHTLDVDALVLAVGAHDRVLPFPGWQLPGVCTAGAAQALAKGERVA
                     VGERVVVAGSGPFLLPVAASLLDVGSRVLEVLEANTAATTARGWGRRPWELAAQAGKAV
                     ELAGHAAVLARHRVPYRTGRAVVEARGDGRVEEVVTARLRADWSVLDGTRRTLAVDTVC
                     VSHGFSPQLELPLAAGCALDERPAPRCGPAGDGGADDARKSGRSGSLGAFVRVDEQQRT
                     SVPWVFAAGEITGIAGAPSARAEGAVAGWSAATGGSTPRDPGRRRALRALRRSRDQGRA
                     FAERLARAHPIGAAWPGWLRPQTVVCRCEETDYGSLCAAFATEAGSASRVAKLNTRAGL
                     GPCQGRICGPTVAELRRRFLGDAPERPAEGLPRADPHRRPIAQPVRLGELAAPSAPLTD
                     PGRRPEEESSS"
     gene            26072..27013
                     /locus_tag="DQ392_RS20525"
                     /old_locus_tag="DQ392_20500"
     CDS             26072..27013
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358495.1"
                     /locus_tag="DQ392_RS20525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20500"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_114017105.1"
                     /transl_table=11
                     /translation="MSDSKQPPRGLGGVVVATALPYREDAAAPAGLAVDYDRYAEHCRW
                     LVERGCHGVGPNGSLGEYSSLTDQERRTVARTAVEAVGGSGTVVVGVHGVGSHQARHWA
                     EAAAEDGADGVLCLPPTMYRANKGEILAHFTEVASVGLPVMIYNNPLDTKVDLTPDLIA
                     EAAQIDNVVAVKEFSGDVRRVLEIRERTAGTGLEVISGADDVVLESLLMGASGWFAGFP
                     NVFPAESARLFELATAGRLAEARALYEPLVAAFRWDSRTEFVQAIKLGMEQVGRFGGPC
                     RPPRGPLVPGLRAQVEADMARAIAALDERAAA"
     gene            27013..28014
                     /locus_tag="DQ392_RS20530"
                     /old_locus_tag="DQ392_20505"
     CDS             27013..28014
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358096.1"
                     /locus_tag="DQ392_RS20530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20505"
                     /product="proline racemase family protein"
                     /protein_id="WP_114017106.1"
                     /transl_table=11
                     /translation="MRSVRTLSAVDSHTEGMPTRVVTGGVPPLPGATMAERRGHAVRHL
                     DGLRRFLVDEPRGHPAMSGALLQPPTRPDADWGVVYVEVSGFLPMCGHGTIGVATVLVE
                     TGMVEVTEPETRVRLDTPAGLVEARVTVRDGAAEKVTLRNVDAFALELDASVTVPGLGE
                     VRYDMAYGGNFYALVELDRIGLPFDRARKDEILAAGLSVMRAVNEQNPPAHPVDPAIGG
                     CKHVQFLAPGSTGRHSRNAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLRTEFVNES
                     FIGTRFVGQLLETVEVGGVPGVVPEFSGRAWITGTANYLLDPRDPFPHGFVL"
     gene            complement(28050..28517)
                     /locus_tag="DQ392_RS20535"
                     /old_locus_tag="DQ392_20510"
     CDS             complement(28050..28517)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQ392_RS20535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DQ392_20510"
                     /product="hypothetical protein"
                     /protein_id="WP_114017107.1"
                     /transl_table=11
                     /translation="MNARRNETEEALASWAEECQANAARLADMLGVPAADYRADPLAAL
                     PAWEDYVSRLPLTDFGESDRVTLHTDLVSFLADFMVRAKGAHWEATPDASAPGGHRYVL
                     TAMGLDGRVRHCDPFAVVHQVSSKLPLDATRVLATAELALGLSRPERDTAH"
     misc_feature    complement(28513..28526)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.74"
                     /tool="antismash"
     gene            28697..29311
                     /locus_tag="DQ392_RS20540"
                     /old_locus_tag="DQ392_20515"
     CDS             28697..29311
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468377.1"
                     /locus_tag="DQ392_RS20540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20515"
                     /product="HD domain-containing protein"
                     /protein_id="WP_114017108.1"
                     /transl_table=11
                     /translation="MGNETRLRELFDFISHTARLREVERHNNAAPERRESVAEHSWHLA
                     MVCWVLHTEFERESGAALDLGRMLKLCLLHDLVEIDTGDPSAWQTARGGEEALARKARA
                     EEAAARDRLGTLPAPLGPELLALWREYEEGATPEARLVRGVDRLNPALMRLLTGQGWAD
                     VDADAAALDRLQLPRVGVSPTLTALYEEVREAAVARGLLAP"
     gene            <29448..29753
                     /locus_tag="DQ392_RS20545"
                     /old_locus_tag="DQ392_20520"
                     /pseudo=""
     CDS             <29448..29753
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324303.1"
                     /locus_tag="DQ392_RS20545"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20520"
                     /product="TetR-like C-terminal domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="RAFRAFVLEHPGRYAATIGVEPSDPDDPLATAGRRLLAAFMAVLR
                     GYAIAESDVDHALRMLRSLCHGFATLQAADGFQRSADVDESFEWLTAFADRGLRAR"
     gene            complement(30044..30772)
                     /locus_tag="DQ392_RS20550"
                     /old_locus_tag="DQ392_20525"
     CDS             complement(30044..30772)
                     /NRPS_PKS="Domain: PKS_KR (5-154). E-value: 2.7e-09. Score:
                     29.1. Matches aSDomain:
                     nrpspksdomains_DQ392_RS20550_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468378.1"
                     /locus_tag="DQ392_RS20550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_20525"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_114017110.1"
                     /transl_table=11
                     /translation="MARDILVTGGATGIGLAVARHFAESGEKVVVTGRRQAPLEAAAAE
                     IGARALVCDHTDPRAVARLQGELPDRLDVLVNNAGGNTDFDAEADEALGELEAFARDFR
                     ANLDANLLSAALTTRAVEGRLAAGGAVVSIGSIAADKGSGAYGAAKAGLASWNLGLARQ
                     VGARDITANLVAPGYIADTEFFRDKLTAERRDALVAATALGRPGAPGDIAGAVAFLASP
                     AARDITAQVLHVNGGERGTR"
     aSDomain        complement(30311..30757)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS20550_PKS_KR.1"
                     /evalue="2.70E-09"
                     /label="DQ392_RS20550_PKS_KR.1"
                     /locus_tag="DQ392_RS20550"
                     /protein_end="154"
                     /protein_start="5"
                     /score="29.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVTGGATGIGLAVARHFAESGEKVVVTGRRQAPLEAAAAEIGARA
                     LVCDHTDPRAVARLQGELPDRLDVLVNNAGGNTDFDAEADEALGELEAFARDFRANLDA
                     NLLSAALTTRAVEGRLAAGGAVVSIGSIAADKGSGAYGAAKAGLA"
     CDS_motif       complement(30668..30757)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS20550_0001"
                     /evalue="6.90E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="DQ392_RS20550"
                     /protein_end="35"
                     /protein_start="5"
                     /score="28.3"
                     /tool="antismash"
                     /translation="LVTGGATGIGLAVARHFAESGEKVVVTGRR"
     misc_feature    30750..30765
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
ORIGIN
        1 gcaggttgag gacggcgggc accagcgcca tgcggacgac gaacgcgtcg aagaagacgg
       61 ccacggcgag gccgaaaccg atcatcttca ccatcgagtc gctggagccg atgaacccgg
      121 agaagacggc gatcatgatg acggcggccg cggtgacgac ccgcgcgccg tgccggaacc
      181 cggtcaccac cgcctcccgc gccgactccc cgtgggcata ggcctcccgc atccgggtca
      241 ccaggaagac ctcgtagtcc atcgcgaggc cgaagaccac acccaccatg aagatcggca
      301 tcatcgacat gaccgggcct gtctgctcca cgccgaacag tccgccgagc cagccccact
      361 ggaagaccgc gaccacggcg ccgagcgcgg cgacgacgga cagcaggaag cccagcgcgg
      421 ccttcaacgg caccagcacg gagcggaaga cgaccatcag cagcaggaac gccaggccga
      481 ccaccagcgc caggtagggc agcagcgcgt cgttcagctt ctgcgagacg tcgatgttca
      541 tcgccgtcga cccggtgacc aggacgtcgg cgcccgtctt ggggctcagt tcggcacccg
      601 tgtcgcggat gtcgtgcacc aggtcctggg tctgcgtcga ggacgggtgc gagtcgggga
      661 cgacggtgac catcgccgtg tcgcccgcct tgttgaactg cggctcggcc acccccgcga
      721 tgccgtccag ccgggacagc tcccgcacgg tgtggtcgac ggcggccttg ggatcgtcgc
      781 tgccccgggc gtctatcacg gtcatcaggg ggccgttgaa gccgggcccg aagccgtccg
      841 acagcaggtc gtaggccttg cgctgggtgg tgtccgtcgg cttcgacccg tcgtcgggca
      901 ggccgagttc gagggaggtg gccggcaggg cgatcacgcc gaggcccacc acgccggcca
      961 gcagcacggc gacggggcgc cgctggacga accgcgccca gcgggtgccg gcaggctccc
     1021 tggccggcgg cttcccggcc tgctcccccg ggtcggctgc ctgcgcggtc tgcgcggcct
     1081 gtacgccggc ctcccctgcc tgctcgcgtg cctgcttgcg tgccttgcgg ccgacgatgc
     1141 ggctcccggc gaagcccagc aaagcgggga tcagcgtgag ggccaccagc acggcgatgg
     1201 cgacggttcc ggccgccgcg acgcccatct tggtgagcat cgggatgttg acgaccgcca
     1261 gcccgaccag cgcgatgatg accgtcagac cggcgaagac caccgcggag cccgccgtgc
     1321 cgacggcccg ccccgcggcc tcctcccgcg cgcggccctc gtggagttcg gcgcggtagc
     1381 gggagacgac gaacagcgcg tagtcgatgc cgaccgccag gccgatcatc atggccagaa
     1441 tggaggtggt ggagcccagg tccatcacac tggcgagcgc ggtgatcgtg gagacaccga
     1501 tgcccacgcc gatcagcgcg gtcagcagcg gaagtccggc ggcgaccagc gagccgaagg
     1561 tgacgaccag gacgacggcg gcgaccacca cgccgatgac ctcgccggcg cccgtcgtcg
     1621 ggatggtgct cagcgcgtca ccgccgatct ccaccgtcat gccgccgtcc cgcgcctgct
     1681 caccggtctt ctcgagcgcg tcgcgggtgt cgtcggacag ctccatcgag ctgaccttgt
     1741 agttgaccga gatgtaggcg gtctcgccgt ccttgctgac ggccttgccg gtgaacgggt
     1801 cgatgaccct ggccacctcg tcggacccgg acttcagcgc ggcgacggcg tcctggaccg
     1861 cggccttgtt ggccgggtcg gtgatcttct cgcccttggg tgcgtcgaag acgacgcgcg
     1921 cggtggcgcc gtcggcgttg gcaccgggga agcgctggtc cagcaggtcg aaggccttct
     1981 gggcctcggt gcccggaatc gagaaggagg tggaggcggc gggcggcgcg ctggcggcgc
     2041 ccgcccccgc tatcgcgagc aacgccaccc acagcagcac gacgatgccg cgccgccgga
     2101 aggcgagccg ccccaggcgg gagaggaagg ttgccacggg tggaactcca gaggtgatga
     2161 gggacccgcg aggcgccggc gcgcacgtcg ctggacgcgc ggggccctgg gtgcgggtgg
     2221 agctggtgga gagaggaagg agagggggtg tgccggcttc aggcgcgcag tgcgggcagc
     2281 acgacggcgt cgaggtaggt ggccaggaag tcctgggttg ccgcgagtcc ttcgatcagt
     2341 tcgcggctga tcagcgcgcc gacgagcatg tgcggcacga aatcgagagc ggggttgtcg
     2401 gagcggatct cgccccgctc caccgcccgg tcgagcatca cgtgcaggtc ggcgatgctc
     2461 ggttcgatca gcagctcgcg cagggctctg agcagctcgg ggctgtcgtg ggccgcgcgg
     2521 cccacaccgc gcatgagcgc ggcgtcctgt tcgatccggc agtcgtcgaa cgcgtgcacg
     2581 atggcgtccc tgaggtcacc gcgcagcgag cccgtgtcgg cgacacctcg cgcggcgcca
     2641 ggtctcccgt gcttgagcgc gcgggcgacg agctcgggct tgctgcccca ctgccggtag
     2701 agggtggcct tgctggagtg cgtagcggtg gcgacggcgt ccatggtgag cgcgtcgtac
     2761 cccacctcgc gcagcagttg gagcacggcg ccgtagagct ccgcctcgcg ctccggagtg
     2821 attctgctgc gccgcgtcgc tgccacggac gtcattccgg cacctccagc agtacgaaac
     2881 ggtttcgtac tgctactgac catacggcac cggcgagcga aacggaaacg tttcgatgag
     2941 gggtgcgtgc cggtcgcctc gaccggctcg gcccgatcac cgagccgagc cggtcgggcg
     3001 gttcaccgca ccgtcagcac cagcttgccg tccaggccgc ccgcctcacc ggcgcggtgt
     3061 gcccgcgcgg ccccggcgag ggggatcggc tcgtgcagcg gcacgtcgag cgtgccgcgc
     3121 cggtgcaggg ccagcacccg gtcgagggcc tcaccggtgc gctcctcgtc ggcggccccc
     3181 gaggagaagc gcacgccgag cgactgcgcc gcctgcggat cggccagcgt cagcacccgc
     3241 gccgggccgc ccaccagccg cacggactcc cccagcacgt ccgcgcccga ggcgtccagc
     3301 acggcggcga ccccgccggg ggcggcggcc cgcacccggt cggcccagcc gttcccgtac
     3361 gtcacctgcg tggctcccag gcgcgtcagc cgctcccgct cccgctcacc tgccgtgccg
     3421 accacgtgtg cgccgctctc cagcgcgaac tgcaccgcga ggttgcccac ggccccaccc
     3481 gcgccgtgga ccagcacggt ctcccccgcc gcgacctgaa gttcggtgag ggcccggtgg
     3541 gcggcctccg ccgcgaccgg caacccggcg gcccgccgca cgtccaggtc gtcgggccgc
     3601 cgccgcagcc gcgcggtgtc ggccagcagg agcgaggcgt acgcgctggg tgcgcggccg
     3661 aagacctcgt cacccgccgc caggtcgccg acgccgtcgc ccaccgactc gaccgtgccg
     3721 gcgaactcca gcccggggat gtgcggcagc gtgacgggca tggcggtgac catggcgccg
     3781 ctccggatct tccagtccag cgggttgacg cccacggccc gcaccgcgat ccgcacctgg
     3841 tcggggtcgg gctcggggac gtcgataccg gtcggctgga ggacctcggg atccccgtag
     3901 gtggcgaagg cgatggcctc gggcatggcg gacacctgct ttcctctggg tggctcagtc
     3961 cgcccgcgtt ccccgcgcgg gggctcgcca tgcccgctcg ctcgccgtca ccgacctggc
     4021 tcccggctcg ccccctcccc cgccaccgag tccgtcacag ggtcggccgg gtcggggaga
     4081 ctcgtccccg tgccgccggg cgtctccgct gcgccggtcg ccacccggct gttgcggcgt
     4141 ccccacagca ggtagatcag gacccccacc gccatccacg ccaggaagcg cgcccaggtg
     4201 atcagcggca ggctgcccac caggaccagg cacagggcca gcgccaccag gggaagcacc
     4261 gggacccacg gcgtacggaa agcgcggggc aggtcggggc ggcggcgccg gaggtagatc
     4321 acgcccacgc acacggcgat gaacgaggtg agcatcccga tgttgccgag ttccgcgagg
     4381 tcctggatgg gcagcagtgc cgtcatcagg gccaccatgc agccgagcgt ccaggtgatc
     4441 cggcgcgggc tgcgggtgac cgggtggacc cgcgcgaacc agccgggcag cagccggtcg
     4501 cggctcatgg cgaggaagac ccggctctgc cccagcagca tgatcatgac gacggtcgtc
     4561 agcccgcaga tggcgccgac gccgacgacc cgcaccgccc agtcctcacc cgcggcctgg
     4621 agcgcccccg tcaccggggc ggcgttgtcc agttgggcgt agggccgcat cccggtgacg
     4681 accagcgaga cggcgacgta gagggtggcg caggcggcga ccgtggccat cagcgcgatc
     4741 ggcagggtgc gctgcgggcg cttggcctcc tccgcgctgc tggccatgat gtcgaagccg
     4801 gagtacgagc cgaacacgat ggcggctccg gtgaggattc cggcgaagcc gaaggtggcg
     4861 ttcgtactga tcccggccca gcccagcagc ggctgctccc agaagccgcc ctcggctccc
     4921 gcgggacggg actcgggcac gaacggcgcc cagttgtccg ggtcgacgtg ggagacgccg
     4981 acgaccagga agagcacgat ggccgccaac ttgaccagtg tcatggccgt gttgaggcgt
     5041 gaggtggtgc gcacgccggc ggccaggatc gcggtgagca cgaggatgac ggcgaccgcg
     5101 ggcacgttga cggccgcctc gggtccggct atggcctccg ggagccgtat cccgaaggtg
     5161 gccaggaagt cggtgacgta ctgggaccat ccggcggcga ccgcgccggc tcccatcgtc
     5221 atgtcgagga tgaggtccca gccgatcagc caggcgatcg gctcacccag tgacacgtaa
     5281 gcgaacgtgt aggcgctgcc cgcgaccggc accgtgctgg cgaactccat gtagcacagg
     5341 gccaccagcc ccgagacgaa ggcgcccagc gcgaaggaga gggcgatggc gggtccggcg
     5401 tagttggctg ccgcggtgcc ggtcagaacg aagatgccgc cgccgatggt gacgccgatg
     5461 cccatcatcg tcagctggag cggccccagc gtgcggttca gccgggtggc ggggcgctcg
     5521 gcgtcccgca gtgtcgcttc gatcgatttg gtgcgcacgc gtccctctcc tatgcctggg
     5581 cgtccacgcc ggcgcctgac gcgtccgcgt gggcgtcccc gtgtgcggcg tcggccgccc
     5641 ggacgccggg cgcctccggg tgggcgccgg gtgcgtccgg gtgggcggtg gtctccgtgt
     5701 ctgcccggca ctccgcgagg caggcgggca gctgttcggc caggtgggcg tagtcggcgg
     5761 cgtcgttgta caggtgcgcg gacagccgca ggaagcctcg gccgttccag gtggtgcagg
     5821 cgacgtcgca gccggtgcgg gcggagatgc ggcgctggag cgcgtgcgcc gcctcctggt
     5881 cggcggccag ccccgcgggc agcggcacca gccgcatggc gggcgcggcg caggcggcca
     5941 gttcggccgg cgcctcggtg cggcccagtg ccgcggcgag cgtgtgctgt gccgcgtcgg
     6001 ccagttgcgt catccgcgcg cgggcggcgt cccagccgta gcggcgttcg atgaactcca
     6061 gcgccgcggg ggccgcgagc caggcggtga ggtccgcggt gccctggtgg tcgaaccgct
     6121 gggggaacgg ctcgggcgcg ccccaggagt cgacgacggg gtacagctcc tgggcgaggg
     6181 ggccccgcgc caccagggcg cccgtgccgc gcggggtgca gggccacttg tgcaggttgc
     6241 ccacccagta gtcggcttcg cccgcgtgcg cgagggggtc ggcgagcatg ccggggccgt
     6301 gggcgccgtc caccagcacg cgggcacccg cgctgtgggc gacacccacc aggtcggcga
     6361 ccgggaacag gcgggcggtc gccgaggtga tctggtcgac gacgaggagg gagacgggcc
     6421 cggcggccag tgccgccccc acccgtgcgg tgatctcctc agccgtggcg cccagcggca
     6481 ggtgcaccgt gcggacgcgc gccccggcac ggcgtgcggc gcgttcgacc gcccagacga
     6541 cggcgccgta ggcgtggtcg gtcagcagca cctcggtctc cggcggcagc gtgatgctgc
     6601 ccagcacggc gctgacgccc gcgctggcgt tcgccaccag cgccaggtcc tcgggcgggg
     6661 tgcgcaagta gcgggcgatg tgcgtgcggg cgtgcgccac ccgctcgggc aggccgcgga
     6721 accacgggtc gggccccgcg tccatctccg tccgcagggc ctgctgcgcc gcgagcgccg
     6781 cgcgcggcac cgcgccgtag gagccgtggt tcaggtggcg gacggccggg tccagtgccc
     6841 agtcctcgaa cgggtgcccg gcgccctggc cgggttcggt ggagggggtc atacgcagaa
     6901 cggcctcgca gagttgtctg atgacttgct gacgttctcc gggacggtag acggcaatgc
     6961 ccttgtccga caggggtgga cgagtaaatt tcactccctg acccgacggc tcgacgagga
     7021 gtcatcagat gacccgcgtg tgtcacgttg ctgcccgggg gtgtgtcatc gttgctgcgg
     7081 cggcacgccg ggcccacgga cgtgcgcggg cacgacggcg gaacgggaac gggacgggag
     7141 cggaacgggc gacatggcgg cgacggacac ggcggcgcgc ggactgcgcg ccatgctcgg
     7201 cagcggcgaa ctgaccccgg gccagcagct gccccccgaa cccgaactct gctcccgcct
     7261 cggcgtctcg cgcggctccc tgcgtgaggc cgtccgctca ctggccgccc tcgggatgct
     7321 ggagtcccgg cacggctccg gcacgtacgt ctccgcgctg ctgcccgcgc agatgctcgc
     7381 gggattcgcc gccacggtcg acgtgctgcc gctggacggg ctgctggagc tgtacgacgt
     7441 acgccgcggc ctggagtccc acgcggcggc cctggcggcc gcccgcgccg aggacggcgt
     7501 cgtcgaccgg ctgcgcgcac tccacgcgcg gctgtccgtg accgaggacg acgacgaact
     7561 ccacgacctc gaccgcgagt tccacgccac cctgtgcgcg gcgagcggca acgacacact
     7621 cgccgctctg tgcgacatcc tccgctcccg cggccgccac tacagcgtct acggcaccga
     7681 ggagacggac gccctgcgga ccgccagcga cctcggccac gaagccctca tcgccgcgct
     7741 cgccgcccgc gacccccagg cggcggcggc cgcggccagc gcccacctgt cccagacgga
     7801 acgctggctg cgccgcctgc gtcccacccc cggctcgggt cgctgaggtc cgcgcgcggt
     7861 ggcgcgcggg acccggcccc gccgtgggag gctcggatga acgaccaccc accgccgtag
     7921 ggggcagcac cgtgccgcga gagaccggca gccactgcga cgacgccctc cgcgtcgtcg
     7981 actccgcagc cctcgcccgc gcgctccccg tgggcgaggc cgtcgaggcg ctccgcgcgg
     8041 cgctgcgggc cgggctggac gtcgccgcga cgcctccccg ctcccgcgtg cccaccagca
     8101 cggggcaact cctgttgatg cccgccgagt acggggagca cgcgggggtg aagatcgccg
     8161 gggtcgtgcc gggcaacccg gcgcgcggtc tgccgaggat ctcgggcgcc tatctgctca
     8221 tggacgcgac gacgctgcgg cccaccgccc tgctcgacgg ggaggccctc accctcctgc
     8281 gcacctcggc ggtctccgcg ctggcggccg accacctggc ggcaccggac gcgggacggc
     8341 tggtggtctt cggtacgggg ccgcaggcgt tcgcgcacgc cgtcgccctg caccaggtgc
     8401 ggccgctgag cgcggtgcag gtcgtcgggc gcgatccgca gcgggtggcc cggttcgcgg
     8461 agcgctgcga ggaggtcggc atgaccgcct cggccgcggc gcccgacgcc gtggcggacg
     8521 ccgatctgat cgcctgctgc acctcgtcca ccgccccgct gttcgacggc cgcgctctgc
     8581 cggcgcacgc ggcggtcgtc gccatgggct cccacgaccc cggtgcccgc gagctggaca
     8641 cccgcacgct cacctcgggc acggtggtgg tcgaggacgc ggcgaccgcg ctcagggagg
     8701 ccggggacat cgtgatcccc gtccaggagg gcgcgttgag cgccgcgtcg ctggtgcctc
     8761 tcgccgacgt cgtgtgcggc cgccaccccc tcgcggacgg cgggccacgc gtcttcaagg
     8821 gcacgggcat ggcctggcag gacctggtgg tcgcggcagc ggcggtgtca ggacccgcgt
     8881 gaaggtcagg cgcggcgcag ccggatcagg cgcggcgcag ccgggggaag gacggtacgg
     8941 cggcgaggaa gaagagcgtg gtcaaaacgt acggccaggt gagggtgtgc ccgccgaacg
     9001 gggcgaagaa ggaggtgacc gccacggtca gcacggtcga ggccacggcc ccgacgacgc
     9061 cgtacaccag cgcggccacg ccgcgttcga ggaagacggc gcccagcgcc atcgccacca
     9121 ggaccgcatt gtatccgagc agcccctcgg ccacgtcgga ggcgggcgcg cccagcgccc
     9181 aggaggtggc ggtgccgacc acgctgccga ggcaggcggt cagtcccgcg aaccagtcgg
     9241 cgacgaagat ccccgcgagg aagagcagcc ccacgtacca ctgcggcatc aggaagatct
     9301 ggccgacgtt ggcgaggacc gcgtgtgcgg cgtcgcccag ccccaacgac gcgtcaccgg
     9361 acgccgagcg cggcagcgcc gagagcgacg acccctcgtg ccacacccgt tggaagccgg
     9421 gcgccgccac ggtcacgacg ccggccacga ggcagaacgg cagcgtgaac gtcggtatgg
     9481 accacggacg cagcaggttg accagcgcgg cggtgagcac ggacgcgacg accgctcccc
     9541 ccgccgccat cagccacgtc gaggcgtggc caggcccgag gaaaaccgcg aacgccaccg
     9601 ccacgaggca gccgttgaac ccttcgagtc ctgcggccgt ccgctcccgg tcgacaccca
     9661 gcgcgtgcgc ggtggccgtg cccagtgccg tgcccagcag tccggcgagg ccgtaccgcc
     9721 agcccgcggc gaacagcgcg gcgacgaaga agaggccgca cgccgcgttg ggcatgaagt
     9781 ccacctgcgc gatcccgcgc agcacctcgt agccgaaacg caccggctgc cgccgtgccc
     9841 cgctcggctc gggcaggtcc cacgcgacgg aacgactcat acatgtaacg tacatccgtc
     9901 ccgggctccg cccgtgtccg ggccctcaag gctcccagag cccggagaag ggcggtggcg
     9961 gcgtcgcgtg cggcagccgc cggaaacgca cgaaggccgc tcagcgcagc cccgcgcagg
    10021 acagccatcc ccggttgccg cccgtggcgg tgagcaccgc ggcgagcgcg ccccccgcgc
    10081 caccgagcag accgcaccgc tcccccgcga gcgaccacaa ctcgtcctcc tgcgcgacga
    10141 agtgcctcag cagcctctcc cgcagggccg cggccgcagg cagccgcccg tgccgccgca
    10201 tcgcgtcggc cactgccagc accccggccg ccccgtggca gagcccgagc cggtcccccg
    10261 ggtggtcgcc gaagaggtgg aagccctcgt ggtagccgtc ggcgagcgtg tggaaggcgg
    10321 cggccgccca ggccgcgccc accgggtcgc cgagcgcgtc ggccgcgtcc cacagggccc
    10381 aggagacgcc tggtgtcccg tagcaccatg cctgacgcgc gtgcgccccc ggcggccgtg
    10441 cctgcccgtc gagaccgcag cccgtccagg tacggatgtc acgcgcgtcg tcgaacgact
    10501 ccttcatcag ccatcggctc gtgttccgca gcgcggaggc cagttccggg cgcggaccca
    10561 cctgccgtac ggcggcggtg agcgcggcgg tgacacccgc gactccgtgc cccatgcccg
    10621 tgttgatccg cccgtgcagc cagcccagta ccgggtgcgc ggggtagtgc gcgcgcagcc
    10681 ccggcaactc ggcgccgtcg cacagggcgg cgagccgcgc ggcggaggag aggtacgccg
    10741 cgcaggcggc aggaccgtac tccgcctccc ctgccgtgcc cctcgcctcg tgcccgtcgg
    10801 cggtcagcgc caggagcacg ccggaggggc cgagaatcag gtcgtagtcg ggaaacgtga
    10861 ccgccccgta ccgctcggga gcaccccgcg gacggccggg cggctccgcg ccgcctgcgg
    10921 agggccgcgc cgggtggtcg aggagccggt ccctgagccg gtcggccacc gggtgcagtg
    10981 cgggatgcag gacggcgcac tggcgcagcc cgacgagcgt cccggcgagc ccgccgtcga
    11041 acagcccgcg gtggccgggc ccgcgcccgg cgtcccgggc ccacacggcg gccgcgcgcg
    11101 ccgcgaccgc cgcggcctcg gcgtctccca tggcggccac cagccgcgcc aggacgggga
    11161 cgccggggtc gcccgggtgg tcgacggagg cgatggcggg cgtcgagggg ccggagcccg
    11221 cgtgtgcggt ggacctgcgc gccccgtcgg cggggcggac ccgtcccgcc gcctcggcgg
    11281 gccggtcccc ggcggagtgc cgtgccgcgt gcccgggctg acgggccgcg tccgcggccg
    11341 ggacggcttg tgcggaccgc cgggccgggt cggcggtccc ggccacgtcg gtgtgccgcc
    11401 gcacccggtc ggggggccgc tgcgccgccg cgcgtctggc ccggtccgtc cactggccga
    11461 gcgtcgcgac agcgagccgc agggccagcc tccgtgccgc cgtgtcgggt gtgagtgctt
    11521 gctgggacat gccgttcgta cccccttcaa agtggtgctg tttcgggtcg tcctcgtccg
    11581 ggttcgcgtg cgtgccgtcc ggattcgcgt gcgtgctcgc tcgggttcgt gccgcttcgg
    11641 cgaggagccg gggatcgagc gcacgccagg agggcgggcg ggcccgcgac ggcgaacggg
    11701 tgcggcgccc cgcccgcacg ggtgcctgaa ctgccgcgac cagggccgtc gggagggact
    11761 tcgggagggg tgggtgagcc gcccggccgg tccgcgccgg ccgggcggct cacccgctga
    11821 gcgggatcag cagacgatga cggtgcagac gagcaccgtg cacagaccgc tacagccggc
    11881 ggtgtcgagc tgcgtctcgg gcagctcggt cgtcgaactg atccgggtgt cgaggtcgtc
    11941 gatgaggctg tcgaggtcga gctcgggcgc ttcggtcatc actggcatgg tgactctcct
    12001 ttgtctctca ctgcggatgt ggtgtccgcc ccggcgtccc gccaccgttg gaggagggcg
    12061 ggacgccggg gaggtcgatg gcgccgcacc aggcggcgtg agcgcgtgcg gcgaggtgtt
    12121 cggccgtgcc gtcgtggggc agccggacca gcagctgggc cgccgtcgcg ccggaggagc
    12181 cgtcggctgc cggcacctgg gcgctgcctg aagcgggcgg ctcgtccggt gacggcagcg
    12241 cctcctcgaa caccaggtcc tggccgggtt ctgcctggca gagccgctcg actgcctgca
    12301 aggcgggcag ggccgcgagg tcgacgggca gcggcttggt gtgcgggtgc gcccgcaggt
    12361 agccgaacct gggcagtccg gccgcccgcc gcagcgcggc gagtgccgcc accttgtcgg
    12421 cttcgctgtc cgtcaggcgc cacagtgcgg cgcgcgcgat ccgccactgc gcggggctga
    12481 cgacgaggag cccgccgacc gtcagccggg gcacgtgccg ggcccggggg aacgccccgg
    12541 ccagcccgtc caaccgcacc atgcgccggg tggccggatg cccggccccc gtcagcagcg
    12601 gcagcagccg gtcgtacggc ggggccgggg tgcgggtggc gtggtggacg ggcagtaccc
    12661 gtaccccgtc ggcctcggcg acgagtgcgc cgcccgcgac ccgcagggtg acccggtcga
    12721 gagggaggtg acggacggaa ggaagcggtg tgacgccccc gccgccggcc gccgggcggg
    12781 gatcggccga gttgccgtag tacagcggag tgttggagtc ccccgtacac cagctggtgg
    12841 agacggggcg gcgtaccgcg ttggccgccg cttcggtcag cggcgggacc agcacctcga
    12901 cgaagcgcac accggcgcgc cgctcgaagg ccgcgaggaa gtcccggtag ccggccgggt
    12961 tggggtatcc ggcggcgggg ctgccgccgt acagctcccc cagcgcctcg gcgaagcggg
    13021 cgtccaggac gcccgcgggc gacgccgact ccaacacggc caaggtgccg gggtgttcgg
    13081 ccacgtcgag cccgcgctgc ccgcgtggcc ctccgcggcg ggcgcgggcg cggggcagtg
    13141 gccgcagcag acagtcgacg ggccaggtct gaagcaccgc aggcaccggc ggcgccccga
    13201 cctcgtccag gagtgcggcg tccacgtcga cctgctcctc gtcgagccgc gcgccgaggt
    13261 acgccagcag cctggcgtat ccggagtcgg aggtgtgcgc gggctcccag caggcgtacc
    13321 ggccgcgggt gcgcggggcg gcgggccggc cgtccgcgtg gtcggcctcc aggagacgta
    13381 cggcggaaac gggctcggca cccaggccca cggcctccgc cacctcctgg cgcttctcgc
    13441 ccctgccgcg gttcgcctcg cacagctcgg ccacgcgccg cgcgagcgcg agcccgtccg
    13501 cgacggtccg cgcggcggtg tccggcacct ccgcgcgggg atcggtgccg tcgtcgcgcg
    13561 ggtcggtcac gtcggggtac ggggcggtgg cttcggggcg cgggtcagtg acttcggggc
    13621 gggggtcggt ggcctcgggc cgggacgagg tgacgtcggg ccgggaggag gtgacccggc
    13681 ggtaggagtc caggaaggag ccgcgggcca ggccgccggc cagcggtacg ggcaggccgg
    13741 gcctgtgctc cgtccacggc aggcggcggg cccggggcgc ggcacacacc tggaggatgc
    13801 ccagtgtgtg caggtgggcc aggaaagcgc gcagtgcggg ctgggaggac ggcgggccga
    13861 gcgcggcctc cagcgacccc accgtgcggg gtgtggcggc gagcagccgc atcaccgcct
    13921 ccagcgccgg tgtacgccgc agcgagagcc gccgcagccg gccgcccccg cccgtgtccg
    13981 ggtcgacgac ggagaagtgc aggtgcccca ggccgggttc gccggtggcg cggtgcagcg
    14041 gagcgggcgt gaggagcagg tgcggtgcgg cggcggacag gtcgaggtcg cgtagcaggc
    14101 accacagccg gtgcacgttc tcggtcctgc gcgcggcgac gagctgcggc cctgggcaga
    14161 actccggcag cagcgctacc gcgggaccgc tcggctggca ttccggggag gtgccgggtg
    14221 cgaacgggcc tggcagcggg tcagcggcgg gcaaagaccc cgtcgggccc cccgccacga
    14281 gggggcggcg cgacggcgag gcggataccg gtcgccgccc ggccacgggc accacggcga
    14341 gctgccccgc ccagtcgcgc ggagtggtct tggcggcggc ccggcccagc gcacgccaca
    14401 ggtatccgac gcccttgcgc tgccgcttgc tctcccagag ctcgcccgcc gccgcgcgcc
    14461 gttccaggtc tgccacgaca cggggtgcgg ctccctcgac gaagctccgc agcacgggct
    14521 gcgagcgggc cgcctccagc agcatcgcgc tcaccctgtc ccgctcggcg gcgacggcac
    14581 gcccgaagcc gccgtacgcg gtgcggagcc cggccgcgtc ggccgccagc gcccgcaagt
    14641 cgcgtccgag ggcgggccgt agcgcggcga tgcggtcgag gagggcgtcg tcgtccgccg
    14701 cggggccggt ggggtcgggg agacgagcgg tcccgccttc gccgctgtcg gtggccggcg
    14761 cgtcccccgc gtgcagccgg cggcgcaacg ccagcacggc ccgccggtcc cccgtcgtca
    14821 gatcctcgtg cggtacgacc tcctcgccgg tccgcacgct cagcgcgcgg gcccgcgcga
    14881 ccagccgcgc ccgcctgtcc gccagttcgt cggcctgcgc gaagagggcg gggctcccgg
    14941 cgccggccca gaccgcgccg ggaacaccgg cgagccgcag cagcgccgcg gcaccgaggg
    15001 gcgcggacgc gctgtcgcgc gccggggtgt ggtcgggtga cgcgtggggg ctgtgccggg
    15061 ggccgggggt cgcgcgggcc ggatcagtgt gccgctgccg aggtggcatg cgcggccctc
    15121 ccctcgtgca gcagcgcttc cgtcaggagg ctctggcggg ccagggacag cagcccgcgg
    15181 ttccagtgga agacggtgag acaggcggcc gccgtacggg gaccgacggt ggcctcaccc
    15241 gcctcgcacc cctctccggc cgcgccgtgc gacgcgcctc ccgcctcgaa gtggccgtca
    15301 cgccagcgca cggccgcccg gtgcgccgcc tccgcgtgcc gggccaaggc gtccctgcgg
    15361 tcctcgggaa aggcgcgcag tgcctcgtcg cggggcgtcc gccagtaggc gacgatgccc
    15421 gcggccgccc gctcgcgggc cgccgggtcg acggccgcgg ccgcgtcccg gaggcggcgg
    15481 cccgtctggc gggcgaccgc gtcccagaca ccccggtgct cccatccgac gatcccgagc
    15541 ccgtcgaaga cctcccgcag catcagcagc gactgccgcc agccgaccga gggcgccgcg
    15601 ccttccgggt ggtcgacgtg gtggtcgagc caggccaggg agtcgagggt gaacaggtcg
    15661 tgcacgtacg ccatcgaggc ggggccgccg aagaggtagt gctcgggttc gtacaccgcg
    15721 cacaccgggc gccgccgaag cccctcccac cggtcggtac ggcgcagcag ggcggcacgc
    15781 aacgcggcgg cttccccggg ctccgcggcc tggaaacgcg cgcggattcc cggggccttg
    15841 tgcatgaaga agaaattccg cgcccgctcc tcggtgagaa acgcgtcggc gagcgcggcg
    15901 agttccgcgt aacagagcgc gcggccgtgg gagtcgcgct cgggggtcag gttgagctgc
    15961 acccaggcgc cggtgcgcgg cgcgccacgg accgctgttt cccgcgcggc gcggcgcgcc
    16021 gccgcgaggc ccgcggtgaa ccccgcggct cccgcggccg cgacggtgcg accccgcgta
    16081 cccgcctcct tgaagcggtc cacgaatgcg tacggtgagc gccaccgatg ggaaacctcc
    16141 ggcaattccg ccccccttcg cagtgattgc gttaccgcaa tcacgtccca aaggggaact
    16201 tccctgcttt gccgtgagcg aacaaggaaa ccgaattctt catatgaacg gcggttgtgc
    16261 gccggtgcgt tcgcggaagg ccggagcctt cacacgagag aggaccggtg tcttcggcca
    16321 cgcaacagcg ttcctggcac cgcgagggcc gcctttcggc ccccgcccgc cgcggccagt
    16381 cgcgtcaccg gcctcggccg cggccgccct tccccgcccc acgggagcgg ccgccacgcg
    16441 cgcgggcgcc accgtcgcgg ctgtccttcg cccgtgcggt accccgcacc tgccgggcgg
    16501 gcgcgggcac gggcgagacg tggtcctgcc agtgcccggg gcgggccagc gtgtcgggga
    16561 ggcgggtggc cgagtccccg tgggccgcgt tcagttgggg ctgcgtgagg aagagcgccc
    16621 cggacaggtc ggcaccccgc agatcggcgt cgcgcaggtc ggcgccgagg aagtcgacct
    16681 ggcgcagatc cgctccgcgc aggtccgccg cgagcagcag cgcgccccgc agcgtggcac
    16741 cgcgcaaccg cgccttccgc agctgcttgc ccgtcaggtc gccgcggcgc aggtcccgcc
    16801 cgccgagccc cgcacgcgcc cgctcgctga cctgctccag aaccggcccg acccgcgccc
    16861 gccacgcctc gacatcggcg gcgagcaggg cggccacgtc gccgtcgatc agcgcgtcca
    16921 gctcggccgc ccgcgcttcg gcctccgggc agcgaccgcc ccgcgccgcc tcggtgagca
    16981 gccacagcag ctcgtgcagc tgccgcgtca cccggaagac cgcgaacagc cgcggcccgg
    17041 acaccgttcc ctcgcgggcc gtcacccgct gccccgctcc gtagcagtcg aagaccgagc
    17101 acccggtgaa gccgctgacg cgcagccgcg cgtggatcga gcaccggttc tcttcggtca
    17161 ggttcccgca ccgctttccc gccggtttgt cggccgcgaa gtcggccgac ttcgcgaacg
    17221 gcagcgccac acagcacagc cccgcgcacc gctcacagtc ggccctcagc cgttccatcc
    17281 gctccgggcc ttcgctctcg ctcacccgtc caagctaacc gggctcgtcg gccggtgcgg
    17341 tgtcgccctc tcccgggcgg cgggccgggg cccgtgcggg agccggattc agggcttgcg
    17401 ggcgaccgcg ccgaactggg cgacggtctt ctcgtcgtcg gccgcgtgcc cggggcgcca
    17461 gcgggagcag gagatgatgc cggggggcag cagttcgagc ccgcggaaga aaccggccac
    17521 ctcggcgcgg tcgcgggccg tgatcggtgg cgtggcgttc tcgttccaga accgcatggc
    17581 ctcctcgttg gcctcgccgc ccagctccag cgtggggtgg gtgagcacga ggtagctgcc
    17641 ggaggggaca gccgccatca gcgtgtcgac gatgcgggag gcctcgtcgg tgtcggcgat
    17701 gaagttgagg atgcccagca ttatgacggc cacggggtcg acgaagtcga gggtgtcggc
    17761 cgcggcgtcg acgatggcgc tcgggtggtg cgcgtcggcg tcgatgtagt cggtcgcgcc
    17821 ttcctcggag ctggtgagca gggcacgggc gtggatgagg acggtggggt cgttgtcgac
    17881 gtagacgatc cgcgaggacg gggcgacccg ctgggccact tgatgcgtgt tctcgacggt
    17941 gggcagtccg gtgccgatgt cgaggaactg gcggatgccc gcctcccccg ccagataccg
    18001 caccacgtgg ccgaggaagg cccggtccgc gcgcgccacc tcgcggatgc tggggtacat
    18061 gctggtgacg tggtcgccga cctgctggtc gatggcgtag tagtccttgc cgcccagcca
    18121 gtagttccac accctggcgt tgtgcgcgac atcggcgacc ggcgtctcgg cgccctcggg
    18181 accgctgctc tcgctcacgt gccgtgtcct ctccgttcct cacccgcgcc tttcggaccg
    18241 acccgcgccc taggaccgct cgaaggatcc aggaccgctc gtggagtcca gggccgcccg
    18301 aagagtctag ggcggcgacg taccgccggg cacgaccgcg cgcgaggcgg ccgcaccgcc
    18361 gtggggcgcc gggaaaccgg cccgggcgga cgcgccgggc gaagtcgccc gcccggtgca
    18421 cgacttcagc cggcttgggg attcctccaa gcatgattgg cacatgctat agagagaagc
    18481 cattcgcatt gcatatgcga ggttatgagc catacgttga cgcacatgca gtcgtacacc
    18541 atcggccagg cagcccggct gctcggcgtc agcccggaca cggcgcggcg ctgggcggac
    18601 gcgggccgcg tcaccacgca ccgcgacgag agcgggcgcc gtctgatcga cggacgggat
    18661 ctggccgcct tctccgtcga gctcggccgg cacgccgccg acgaggacga cgtcccctac
    18721 accacggccc gcaacgcgtt cgccggcatc gtgaccgccg tcagactcgg tgacgtggcg
    18781 gcgcaggtcg agatccaggc gggcccgcac cggctggtct ccctgctgac gcgggaggcc
    18841 gtcgaggagc tgggcctgga ggtcggcgtg caggccacgg cccgcgtcaa gtcgaccaac
    18901 gtgcacatcg acacgccgta ggcccgccgc cccgcgtccc cgcgtcccga cattccgacg
    18961 cccccggcgt cgcccccgtc ccgtccgccc gccccatctg gagacccacc gcatgtcctc
    19021 gccctcgtcg tcgacgcctt cgccctcctc gccgccttcg tctccctcct cgccgctcgc
    19081 gtcaccctcg ttcccccgct cgctcccgac gcaccgccgc tccctcgccg cgctcgccgc
    19141 cgtcgccgtg ctggttccgc tcaccgcctg cggtggtggc ggcgacggca agggcgacga
    19201 ggcgggcgag ggcgacagga ccgagctgac cgtgctcgcg gcgtcctccc tgaccgacgt
    19261 gttcaaggcc gcggggaagg cgtacgagaa ggatcacccg gacacgaagg tgaccttctc
    19321 cttcgccggg tcccagcagt tggccgccca ggtcgagcag ggggcgccgg ccgacgcgct
    19381 ggtcacggcc gacaccacga ccatggaagg gctcagcgac gagacgggca cgccggatgt
    19441 catcgcgaag aaccggctcg tcatcgccac cggcgagggc aacccgaaga aggtcgagtc
    19501 cctgcgggat ctcaccgaca agaagctgaa ggtggtgctg gccgcgcccg aggtccccgt
    19561 cgggcgctac agcaagcagg tgctggacgc ccagaagctc aaggtcgaac cggtctcgcg
    19621 ggagaccaac gtccgccagg tgctgagcaa ggtggagctg ggcgaggccg acgccggcat
    19681 cgtctaccag acggacgcgg cgacggcgcc gaagaaggtg gacgccgtca aggtccccga
    19741 cggtcagaac gcgatcgcct cgtacccggc cgccacgctc aagggatccc agcaccgcaa
    19801 ggaggcggcg gccttcgtga agtggctgaa gacccccgcg gcgcagaagc tgctgcgcga
    19861 ggcgggcttc cagaagccgt gacccgtacg cgcaaccccg cggggcgtcc ccgcgcgccc
    19921 ctcgcgctgg ggctgcccgc ggtgctggcg gtcgcgttcc tgctggtgcc gctgctcggc
    19981 atcctggtgc ggacgcagtg ggcggagctg ggcacgcacc tgggcagcga gggtgtcacc
    20041 gaggcggtga agctgtcgct gctggtgtcc ggcggtgccc tggcgctctc cctcctgctg
    20101 ggcgtaccgc tggcctggct gctggctcgg atcgacttcc ccggcaaggc gctggtgcgg
    20161 tcgctggtcc tgctgccgat ggtcctgccg ccgaccgtgg gtggtgtggc cctgctgctg
    20221 ggcttcgggc ggcgcgggct gctgggcccg tggctggagg acacgttcgg tgtcgtgctg
    20281 cccttccaca cctcgggcgc ggtggtggcg gcgacgttcg tggcgatgcc gttcctggtg
    20341 atcagtctgg aggggacgct ggcggggctg cggccctcct acgaggagac ggcggcctcg
    20401 ctgggcgcgt ctccggtgcg ggtgttcttc acggtgacgc tgccgctcgt ggccccggga
    20461 ctggccgcgg gcgccgcgct cacctgggcg cgggcgctgg gcgagttcgg cgcgacgatc
    20521 accttcgcgg ggaatctgcc ggggacgacg cagacgctgc cgctccaggt gtatctgctg
    20581 ctccaggacc agccggaggc ggcgacgtcc gtctcgctgc tgctgctcgt catcgccatg
    20641 gccgtgctgt tctcgctgcg cggccggtgg gcgggcgggg cgggcgcctc gcgcacccgc
    20701 ggcggaaagg cgggtggtgg cgcggggggt ctctcgcgcc tccgcgaccg ctggacacgc
    20761 ggcgcggagg gccccgagcc cgccaccgac cccgaagccc cgcacaccac cagcggcacc
    20821 agcaccggca ccggcaccgg caccggcacc ggcaccccgg aagtgtccgc cgcccccggg
    20881 gagtccgacg ccacggtcgc ccacgtctct ccttccgacg ccgacaccga caccgacacc
    20941 gacaccgacc gctgggacct gcacgcgcgg ctcggcggtt tcacccggct cacgctggac
    21001 gccgcgcccg gcaccacggt cgccgtcgtc ggcccgaacg gcgcgggcaa gacgacgctg
    21061 ctgcgcgcac tgctcgggct gaccccccgc gcgcacgccg acctcgccct gggcggcacc
    21121 gaggtcggcg cgctgccccc gcaccggcgg ggtgtggcgt gggtgccgca ggacggagcg
    21181 ctcttcccgc acctgagcgc gctggcgaac accgcttacg ggttgcgcgc cgcgggggtg
    21241 cgccgcggtg aggcgcgccg cctggccctt cagtggctgg agcggctgga ggtcggccac
    21301 ctggcgcacc gcaggcccgc gcagctgtcc ggcggtcagg cggggcgggt ggcgctggcc
    21361 cgcgcgctgg cggcgcggcc gaggctgctg ctgctcgacg agccgctggc cgcgctcgac
    21421 cagacgacgc gcgcgcacgt acgccacacg ctccgcggcc acctggggca cttcggcggg
    21481 gtctgcctgc tggtgaccca cgatccggtg gaggccgtgt cgctggccga ccgggtgctg
    21541 gtgctggagg acggccgtgc cttgcaggac gcgccgcctg ccgaggtggc gcgccacccc
    21601 cgctcaccgt gggtcgcgcg gatgctgggc cgcaacgcac tggcgggcac ggccgcgcgg
    21661 gacggctcgc tggtcctgga ggacggcggc agcctggtgg tcgccgaccc cgtcgcggag
    21721 gggacgcagg tgctggcggt catcgcgccg gaggcggtcg cgctgcaccg ggagcgcccg
    21781 cagggcagtc cgcgcaacgt ctgggcgggc acggtgcggg aggtcacggc ggtcggcagc
    21841 aggatgcggg tcctcgtgac gtgtacgggc cgccccgacc tggtcgccga ggtcaccgcc
    21901 gacgccgtgg ccgagctggg gctggaggac ggcgcggcgg tcttcgcggg catcaaggcc
    21961 acggagatca ccctcgtcga acggtgaccc cgccgccgct cggcaggccg agcgcccgtg
    22021 ccgagggcgc cgcgtcccgc cggcacccgg tcccctgccc gttcgggata atggccccac
    22081 gcccctacag cgttctgtga agcgaacgtt gggcgcgtgg aagaccacag ggaagggagg
    22141 ggccgtgagc ggtcctgaag cggcggagag atcgatccgg ggcatgctgg cgctcaacct
    22201 gaagcgggcg cgggcccagc gggggctgtc gatctcggag ctgtcgcggc gctcgaagat
    22261 cggcaaggcg acgctgtcgc agctggagtc cggcacgggg aaccccacca tcgagacggt
    22321 cttcagtctc tcccgcgtcc tggaggtgcc catctccgac ctgctggacg cgcggccgcc
    22381 cgccggtctg cgggtggtgc gggcccagga ggtggaggtg ctcagcggcg agggcgtgga
    22441 cctgcgcccg ttgcagcgga tcgagtcggg cgggggcgtc ttcgaggtgt acgaccagca
    22501 ggtgcgggcg ggtgagcggc gggactcgct gggccatgtg ggggtggagc acaccatcgt
    22561 gcaggccggg cggctcgggg tacgcgtgga gggccacgac gtggagctgg gccctggcga
    22621 ctacgtcggc ttcgacgcca cgctgccgca cggctacacg gcgctggacg gcaccgtgcg
    22681 ctcggttctg ctcctccagt accgcgcgga ccagcgactg cctccggacg ctccgcaccc
    22741 cgtcgcgggc gggtgcgcac cgcacaccga ggcgtgaggg cgccccagga cgctcggggt
    22801 ggcacgcgga ggcgtgcggc ggcacgcgac ggcatccggc ggcactcccc ataaaggcgc
    22861 tccgccgtgg ccgttgacac ccctgtacgc cgggaatacc gtccctctcg ttcgctttac
    22921 cgaacgagga ggttcgatga acggaacgcg ggccgtggtg ctcggtgccg ggatcatcgg
    22981 tgcggcctgc gctcgcgaac tcgccctggc cggagccgcg gtgaccgtcg tcgaccgggg
    23041 cggccccgcc gcggcgacca cctcgcacgg cgagggcaac gtactcgtct cggacaaggg
    23101 tccaggaccc gaactcgcgc tcgcccagct ctcccgcgaa ctgtggccca ccgtgctgac
    23161 gcaggtcgcc gaacggtcgg cggagggaca ccgggccgcc caggccgccg agtgggaccc
    23221 caagggcggc atcgtggtcg cgacgacgag cgccggagcc cacgcactcg cacggttcgc
    23281 cgacagccag cgctccgccg gtgtgcgggc cgagcccctg gcgcccgaag cgctgcggga
    23341 ggcggagccg tacgtcaccc gcgagcacac cgccgccgtc cactacggcg aggacgcgca
    23401 ggtgcagccg gcgggcgcgg ccaccgcgct gctgacggac gcgctcgccg cgggcgcggc
    23461 gctgcgcggc ggcgaggagg tgtgctcggg ggtcgtccgc ggcggcaggc tcaccggcgt
    23521 gcgcaccacc cacgggctgc tggaggccga cctgttcgtc aacgccgccg gcccctggtc
    23581 cggcgcgctc gccgcccggc tcggcgcacc cgtcggcgtc gagccccggc gcggcgacgt
    23641 cctggtgacg acgccgcagc cgcccaccgt cttccacaag gtctacgacg ccgactacgt
    23701 gggctccgtc ggcagcggcg aggaggagtc acagacctcc gccgtggtcg agtcgacccg
    23761 cgcgggcagc ctgctgatcg gctcctcgcg gcgccgcgtc ggcttcgacg accggctgcg
    23821 gcccgaggtg ctctcggccg tcgccgccaa ggcactgcgg ctcttcccct cgctcgcccg
    23881 ggtgccggtg atgcgcgcct acggcggctt ccggccgtac gtggcagacc acctccccgt
    23941 catcggagcc gatccccggc tgccgggcct gtggcacgcg agcggccacg aaggcgccgg
    24001 catcgggctg tcggtgggca ccgggcggct cctgctccac ctcgtgcggg gcgagccgcc
    24061 cccggtggac gccgccgcgt tccgggtgga ccgcccggcc gtgctccgac cccgccagta
    24121 ccagcagcag gagacgacat gagccctcga ctcgtacccg cacagcgcga cgccacgggc
    24181 cgcagggacc ggccgctgcg cgtcaccgtc gacggcgtac cggccgacgg catcgcgggg
    24241 cagacgctgg cagggctcat gctcgcgtcc ggcaggacct cgtggcgccg ggccccctcc
    24301 ggtgccccgc gcggtctctt ctgcggcatc ggggtctgct tcgactgcct ggtcacggtc
    24361 aacggcgagc ccgacgtgcg ggcctgccgc cggcgggccg tcgacggcga cgaggtcacc
    24421 acccactccc gcgccgggca cggggacgcc gacgggcccg gtcgcacggc ccgggaggag
    24481 cggtgaccgt gcccgccgca cgtcgcgtcg cggtcgtcgg cgcgggaccc gccgggctct
    24541 ccgcggcgca cgcggcgctg gcggcggggg cgcgggtgac gctgatcgac gccgccgagg
    24601 agcccggcgg ccagtaccac cgcacggtgc ccgagacgta cggcccccag cggccagtcc
    24661 gtctccagca cgggtggcgg gcgttcgagc ggcggcgccg ccgggtgctg gcacaccccc
    24721 ggtgcacgtg gctgccgcgg acctcggtgt gggcgctgga gcagccgcag ccggagcacg
    24781 agggcccgcc ccggctgcac ctgctgtgcg cgggcccggc ggacggcgcc gggcgcaccc
    24841 ggcacactct cgacgtggac gccctcgtgc tggccgtggg cgctcacgac cgcgtcctgc
    24901 cgttccccgg ctggcagttg ccgggtgtct gcacggcggg cgccgcgcag gcgctggcca
    24961 agggggagcg ggtggcggtc ggtgagcggg tggtggtcgc gggctccggc cccttcctcc
    25021 ttccggtggc ggcctctttg ctggacgtcg gctcccgcgt gctcgaggtg ctggaggcca
    25081 acaccgcggc gacgacggcg cgcggctggg ggcgccgccc gtgggagctg gccgcgcagg
    25141 cgggcaaggc ggtggagctg gccggccacg ccgccgtgct ggcccgccac cgggtgccgt
    25201 accggacggg ccgggccgtg gtcgaggcac gcggggacgg ccgggtggag gaggtcgtca
    25261 cggcacggct gcgcgccgac tggtcggttc tcgacggtac gcggcgcacg ctcgccgtgg
    25321 acaccgtgtg tgtcagccac ggcttcagcc cccagctgga gttgccgctc gccgcgggat
    25381 gcgcactgga cgagcgcccc gcaccgcgct gcggcccggc gggcgacggt ggggcggacg
    25441 acgcccgcaa gagcggtcgg tccggctccc ttggcgcgtt cgtacgcgtc gacgagcagc
    25501 agcgcaccag cgtgccctgg gtgttcgccg ccggtgagat caccggcatc gccggggctc
    25561 cgtccgcgcg ggccgagggt gccgtcgccg ggtggtccgc cgccaccggc gggagcacgc
    25621 cacgggatcc ggggaggcga cgggcgctgc gggcgctgcg gcgaagccgc gaccaggggc
    25681 gggcgttcgc cgaacggctc gcccgcgccc acccgatcgg tgccgcgtgg ccgggctggc
    25741 tgcggccgca gaccgtggtg tgccgctgcg aggagaccga ctacggctcg ctgtgtgccg
    25801 ctttcgccac cgaggccggg tccgcttcgc gggtcgccaa gctgaacacc cgcgcggggc
    25861 tcggcccctg ccagggccgg atctgcgggc cgacggtcgc cgaactgcgc cggcggttcc
    25921 tcggggacgc cccggagagg ccggccgagg ggctgccgcg ggccgacccg caccgcagac
    25981 cgatcgccca gcccgtccgg ctcggcgaac tggccgctcc gtccgccccg ctgaccgatc
    26041 caggtcgccg tcccgaagag gagagcagtt catgagcgac agcaagcagc cgccccgtgg
    26101 tctcggcggt gtcgtagtgg ccaccgcgct gccgtaccgc gaggacgcgg cggcccccgc
    26161 cgggctcgcc gtcgactacg acaggtacgc cgagcactgc cggtggctgg tggagcgcgg
    26221 ctgccacggc gtggggccca acggttcgct gggcgagtac tcgtcgctga cggaccagga
    26281 gcgccgtacg gtggcgcgca ccgccgtcga ggcggtgggc gggtccggca cggtggtggt
    26341 cggcgtgcac ggcgtcgggt cgcaccaggc ccggcactgg gccgaggccg ccgcggagga
    26401 cggcgcggac ggggtgctgt gcctgccgcc gacgatgtac cgcgccaaca agggcgaaat
    26461 cctggcacat ttcacggagg tggcctccgt cgggctgccg gtgatgatct acaacaaccc
    26521 cctcgacacc aaggtggacc tcacccccga cctgatcgcg gaggccgcgc agatcgacaa
    26581 cgtggtggcc gtcaaggagt tctccggtga cgtgcgccgg gtgctggaga tcagggagcg
    26641 gaccgccggc accggccttg aggtgatcag cggggccgac gacgtggtgc tggagagcct
    26701 gctgatgggc gcgagcggct ggttcgccgg gttccccaac gtcttccccg ccgagtccgc
    26761 ccgccttttc gagctggcga ccgccgggcg gctcgccgag gcccgggccc tgtacgagcc
    26821 gctggtggcc gcgttccggt gggactcgcg taccgagttc gtccaggcga tcaagctggg
    26881 catggagcag gtcggcaggt tcggcggccc ctgccgtccg ccgcgcggcc cgctggtacc
    26941 cggcctgcgc gcccaggtgg aggccgacat ggcgcgtgcg atcgccgccc tcgacgagcg
    27001 ggcggccgcc tgatgcgctc ggtgcgcacg ctcagcgccg tcgactcgca caccgagggc
    27061 atgcccaccc gggtcgtcac cggcggggtg ccgcccctgc cgggcgcgac gatggccgag
    27121 cgccgcggcc acgccgtgcg gcacctggac gggctgcgca ggttcctggt ggacgagccg
    27181 cgcgggcacc cggcgatgag cggtgcactg ctccagccgc cgacccgccc cgacgccgac
    27241 tggggcgtgg tctacgtgga ggtcagcggc ttcctgccga tgtgcgggca cggcaccatc
    27301 ggggtggcga ccgtgctggt ggagacgggc atggtcgagg tgaccgagcc ggagacacgg
    27361 gtgcggctcg acaccccggc ggggctggtc gaggcccggg tcaccgtacg ggacggggcg
    27421 gccgagaagg tcaccctgcg gaacgtggac gcgttcgcgc tggaactgga cgcctccgtc
    27481 accgttcccg gcctcggcga ggtccgctac gacatggcct acggcggcaa cttctacgcc
    27541 ctcgtcgaac tcgaccggat cggccttccg ttcgaccgcg cgcgcaagga cgagatcctc
    27601 gccgccggcc tgtcggtgat gcgggccgtc aacgagcaga accctcccgc gcatccggtg
    27661 gaccccgcca tcggcggctg caaacacgtg cagttcctcg cgccgggctc gaccgggcgg
    27721 cactcgcgca acgcgatggc gatccacccg ggctggttcg accgctcccc ctgcgggacg
    27781 ggtacctcgg cgcggatggc gcagctgcac gcacgcggcg agctgccgct gcgcaccgag
    27841 ttcgtgaacg agtcgttcat cggcacccgc ttcgtggggc agctgctcga gaccgtcgag
    27901 gtcggcgggg tgcccggggt ggtgcccgag ttctccggcc gcgcgtggat caccggcacg
    27961 gcgaactacc tgctggatcc gcgcgatccg tttccccacg gcttcgtgct gtaggcccgg
    28021 gccgcgcccc gcgggcgccg ctgaacgggt cagtgggcgg tgtcccgctc ggggcgggac
    28081 aggcccaggg cgagctccgc cgtggcgagc acgcgggtgg cgtcgagagg cagcttgctg
    28141 ctcacctggt ggacgacggc gaacgggtcg cagtggcgga cccggccgtc gagccccatg
    28201 gccgtcagca cgtaccggtg gccgcccggc gcggacgcgt cgggcgtggc ctcccagtgc
    28261 gcgcccttgg cccgcaccat gaagtccgcc aggaacgaga ccaggtcggt gtggagcgtc
    28321 acccggtccg actccccgaa gtcggtgagc ggcagccggg acacgtagtc ctcccacgcg
    28381 ggaagcgcgg ccagcggatc ggcccggtag tccgctgcgg gcacccccag catgtccgcg
    28441 aggcgggcgg cgttcgcctg gcactcctcg gcccaagagg ccagggcctc ttccgtctcg
    28501 ttccgccgcg cgttcatacg gcacaaccta ctcagcccga cgagaccgcg cgacaccgaa
    28561 cccgggcccg caccggcgcg cggcgttccg cccctgaccg tgctctcgcg cggccaccac
    28621 ccgtcggcgg cgggcgcagg ggtatacggc ggccgcgtcc cacgcccccg gcggcgtccg
    28681 ctaaggtcgc cgtgccatgg gcaacgagac gcgtcttcgc gagctcttcg acttcatctc
    28741 ccacaccgcg cgcctgcgcg aggtggaacg gcacaacaac gcggctcccg agcgccgcga
    28801 gtccgtggcc gaacactcct ggcacctggc gatggtgtgc tgggtgctgc acaccgagtt
    28861 cgagcgggag agcggggccg cgctggacct ggggcgcatg ctcaagctgt gtctgctcca
    28921 cgacctggtc gagatcgaca ccggcgaccc gtccgcttgg cagaccgcgc gcggcggcga
    28981 ggaagccctc gcccgcaagg cccgcgcgga ggaggcggcc gcccgcgacc gcctcggcac
    29041 actccccgca ccactcggtc cggaactgct ggcgctgtgg cgggagtacg aggagggtgc
    29101 cacgcccgag gcccggctgg tgcgcggcgt ggaccggctc aaccccgcgc tgatgcgcct
    29161 gctgaccggc cagggctggg cggacgtgga cgccgacgcc gccgcgctcg accggctcca
    29221 gctgcccagg gtgggcgtca gcccgacact gacggcgctg tacgaggagg tcagggaagc
    29281 ggcggtcgcc cggggcctgc tggccccgta accgccggcg agcgaggtga tccctgtgga
    29341 accggggccc ctgtttccgt ccgcgctgct caccttcctc cacgcggaca ccgcccgtgc
    29401 ccagggcagg gctggacccg acggcagtgg tcgcggccgg cgccttccgc gccttccgcg
    29461 ccttcgtcct ggaacacccc gggcggtacg ccgcgacgat cggcgtggaa ccctccgacc
    29521 ccgacgaccc gctggccacc gcgggccggc ggctgctcgc cgcgttcatg gcggtcctgc
    29581 gcggctacgc gatcgcggag tccgacgtgg accacgccct gcgcatgctc cgcagcctct
    29641 gccacggctt cgccactctt caggcggcgg acggcttcca gcgcagcgcc gacgtcgacg
    29701 agagcttcga gtggctgacc gccttcgccg accggggcct gcgcgcgagg tgagtcctgc
    29761 ccgccacgtc tgcgcgcgag gtgagagccg cacgtcatgc ggggtctgcg cgccaggtga
    29821 gaccgggcgc caggtgagac ctgcacgacg tggggtccgc acgccacgtg gcgctgcgcg
    29881 gcatgtgagg tccacccgcg cggtgagacc cgcacgcgac gtgcggctca cgcgacgtgc
    29941 ggctcacgcg acgtgcggct cacgcgatgt gcggctgcgg gccatgtgcg gggaccgccg
    30001 ccgtccgtcg gcgacctccg ggcgggagcc cggccccgcg ggctcagcgg gtgccgcgct
    30061 cgccgccgtt gacatggagg acctgcgccg tgatgtcacg cgccgcggga gaggccagga
    30121 acgcgacggc ccccgcgatg tctcccggcg ccccggggcg gcccagtgcg gtggcggcca
    30181 cgagggcgtc cctgcgctcg gcggtcagct tgtcgcggaa gaactcggtg tcggcgatgt
    30241 agccgggcgc cacgaggttc gccgtgatgt cacgcgcccc cacctgccgg gccaggccca
    30301 gattccacga ggccagcccg gccttcgccg ccccgtaggc gcccgaaccc ttgtccgctg
    30361 cgatcgaccc gatactgacg accgcacccc ccgcggccag ccggccctcg acggccctgg
    30421 tggtcagcgc cgcgctgagc aggttcgcgt ccaggttggc gcggaagtcg cgcgcgaacg
    30481 cctccagctc gccgagggct tcgtccgcct cagcgtcgaa gtcggtgttg ccgcccgcgt
    30541 tgttgacgag cacgtcgagc cggtcaggca actcgccctg tagccgggcc accgcgcggg
    30601 ggtcggtgtg gtcgcagacc aaggcgcgcg ccccgatctc cgctgccgcc gcctccagcg
    30661 gcgcctgcct gcgccccgtg acgacgacct tctccccgct ttcggcgaag tgccgcgcga
    30721 cggcgagccc gatacccgtc gcgcccccgg tcaccaggat gtcccgtgcc atacagtgtc
    30781 ctccactgat cgttcagtcc taaatttagc cctaaacgta acactgcggg gaggacccat
    30841 ggcaagcgag aaccccgaca ccaccacctc tgcacagcgc gacgaccccc acgcgcccga
    30901 caaccccgtc gaggccatcg ccgccgcctg gcggcgcgaa cgccccggca cccccgtctc
    30961 ctccatcggg atcgtcaccc cgctgtggcg cctggccaaa ctgttcggcg acgaccgccg
    31021 ccgggtgctc gcccgcgccg gcgtcgacac cgccaccctc gacctgctca gcatg
//
