LOCUS       NZ_QOIM01000036        21059 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces reniochalinae strain LHW50302
            NODE_5_length_360709_cov_17.3876_ID_9, whole genome shotgun
            sequence.
ACCESSION   NZ_QOIM01000036
VERSION     NZ_QOIM01000036.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces reniochalinae
  ORGANISM  Streptomyces reniochalinae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 360709)
  AUTHORS   Li,L.
  TITLE     Streptomyces reniochalinae sp. nov. and Streptomyces diacarnus sp.
            nov. from marine sponges
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 360709)
  AUTHORS   Li,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUN-2018) Department of Pharmacy, Ren Ji Hospital
            School of Medicine, Shanghai Jiao Tong University, Pujian, Pudong,
            Shanghai 200127, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-FEB-2016
            Assembly Method                   :: A5-misseq v. MARCH-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003323735.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 01:54:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,751
            CDSs (total)                      :: 6,669
            Genes (coding)                    :: 6,475
            CDSs (with protein)               :: 6,475
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 4, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 66 of 194
            Pseudo Genes (incomplete)         :: 154 of 194
            Pseudo Genes (internal stop)      :: 16 of 194
            Pseudo Genes (multiple problems)  :: 41 of 194
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:03:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 42315
            Orig. end                         :: 63374
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QOIM01000036.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21059
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21059
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21059
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11059](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11059
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    218..232
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            complement(795..2309)
                     /locus_tag="DQ392_RS16350"
                     /old_locus_tag="DQ392_16330"
     CDS             complement(795..2309)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008749333.1"
                     /locus_tag="DQ392_RS16350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16330"
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_114016362.1"
                     /transl_table=11
                     /translation="MHSFDWTVMCAYFGLMVLIGWWSHKRVGNVKDFFTAGGRMPWWLA
                     GISHHMSGYSAVLFVAYASVAYTTGVTVYFWGFASIGVGVGIGSWLFAARWNRLRSKLG
                     VASPLEYLAMRYNVTTQQALAWSGSLLKIFDIAAKWFAVATLLHVFAGIDYNVGILVTG
                     VITLFYCTVGGLWADALTELGQFVIQAVAAIVMLVVVLGKLGGVPALWTMWDKLPAGHV
                     DPTTPKYTGLFLMVYVLVKTLEYNGGMWNLAQRYMAAPDTHAARRSARLSAGLYLLWPL
                     VLMFPMFAAPLLVPDVDNPDNSYAVMTTTFLPPGLIGLVLAGIFSHTMAMVSSDANAIS
                     AVITRDMIPVMYRKARAWTPPQGLLAARVTTVSFVVLTMVVATQAQNLGGVLQLVVNWV
                     AALMGPISIPLLLGMLPWFRRCGPRAALTSWAGGLVGYGLVYYVIDTSQTWLVATPVLV
                     SLVLYAGLGALAPERSETAEELMEVLGDDDTPGTAEPGPEETRLPA"
     gene            2502..3326
                     /locus_tag="DQ392_RS16355"
                     /old_locus_tag="DQ392_16335"
     CDS             2502..3326
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009079530.1"
                     /locus_tag="DQ392_RS16355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16335"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_114016363.1"
                     /transl_table=11
                     /translation="MLRHDGASAAGGAAQAGAPSTEPSGVKSAWRTVELLEAFAAGDVW
                     LSLSDLHASTGFPRSSLHGLLRTLLDAGWLEQDGGTTRYRLGIRALKCGTAYLDRDAVV
                     PFATEVLEQVREQTGYTAHFARRNGDEVVYLETREAQRSTHLVSRVGRSLPVHATALGK
                     ALLAELTHDEVEALLPATLPALTPRTLTSREALHSACAESRELGYASEHEEGTPGIRCV
                     AAVIPYRIPGTDAISCSMPVDRTDDAETRRVGELLAEATAQLARRLRREGIR"
     gene            3422..4246
                     /locus_tag="DQ392_RS16360"
                     /old_locus_tag="DQ392_16340"
     CDS             3422..4246
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (56-174). E-value:
                     5.7e-10. Score: 30.6. Matches aSDomain:
                     nrpspksdomains_DQ392_RS16360_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007829919.1"
                     /locus_tag="DQ392_RS16360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16340"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_114016364.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.9e-07,
                     bitscore: 24.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDQRLLITGAAGTVGTLMRPRLRRPGRVLRLLDLAPQPAAEPGE
                     AVELLTGSVTDAEVMKSACQDVDALIHLGGLSREDTWEATLDVNIGGTHTVLDAAREAQ
                     VPRVVLASSNHAVGFRTTDEGGSDGLPADSSPRPDTYYGVSKAAIEALGSLYHSRFGMD
                     VTAIRIGSCFETPLPLGERGLSTWLSPDDCARLLEACLATTSPGYRLIWGVSDNARRTF
                     SLAEAEALGYTPRDDAEVYAPRLAAPPAPDGTLAELVGGSFCTAPLGRHNPL"
     aSDomain        3590..3943
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS16360_NAD_binding_4.1"
                     /evalue="5.70E-10"
                     /label="DQ392_RS16360_NAD_binding_4.1"
                     /locus_tag="DQ392_RS16360"
                     /protein_end="174"
                     /protein_start="56"
                     /score="30.6"
                     /tool="antismash"
                     /translation="AEVMKSACQDVDALIHLGGLSREDTWEATLDVNIGGTHTVLDAAR
                     EAQVPRVVLASSNHAVGFRTTDEGGSDGLPADSSPRPDTYYGVSKAAIEALGSLYHSRF
                     GMDVTAIRIGSCFE"
     gene            complement(4263..5594)
                     /locus_tag="DQ392_RS16365"
                     /old_locus_tag="DQ392_16345"
     CDS             complement(4263..5594)
                     /GO_function="GO:0045550 - geranylgeranyl reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015995 - chlorophyll biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0030494 - bacteriochlorophyll biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1161: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492427.1"
                     /locus_tag="DQ392_RS16365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16345"
                     /product="geranylgeranyl reductase family protein"
                     /protein_id="WP_114016365.1"
                     /sec_met_domain="Trp_halogenase (E-value: 1.5e-07,
                     bitscore: 24.9, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 1.8e-08, bitscore: 28.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRPAAERAQVIVVGAGPGGSTAAWHLARQGLSVALLEKSEFPRE
                     KVCGDGLTPRAVRQLVRMGIDTSAPGWMRNRGLRFVSRGRTLELDWPECSAFPAYGLTR
                     TREDFDQLLARHAEAAGARLHTRTKVTGPLLDRAGRVVGVSTAGPGGRERDFAAPLVIA
                     ADGVAGRLAVSMGIERLRKRPVGTAVRRYFHSARHLDPYLESWLDLRREDGRILPGYSW
                     IFPLGDGRVNVGLGVLNDSRTGAIQTRRLLETWLARTPAAWGLREPGNAEGPLRGAALP
                     MGFNRLPHYRDGLLLIGDAGGMVNPCNGEGITYAMESAELAADVAGQALARPAGPARER
                     ALEHYPAQMAYRLGRYYRLGRGFSALMARPAFTSLVTQHAVRSPGAMRFMVRLLSNLTD
                     RPGTDAMDHLVNALIRVTPSPADHAGRRFAGAPSVRPGRSRVPG"
     gene            complement(5591..6325)
                     /locus_tag="DQ392_RS16370"
                     /old_locus_tag="DQ392_16350"
     CDS             complement(5591..6325)
                     /EC_number="2.1.1.163"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003974389.1"
                     /locus_tag="DQ392_RS16370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16350"
                     /product="demethylmenaquinone methyltransferase"
                     /protein_id="WP_114016366.1"
                     /transl_table=11
                     /translation="MPRATLAKQPDAVSAMFDQAARRYDLTNTLLSAGADRTWRARTRE
                     ALGLRPGERCLDVACGTGVSTEALARSGAAVVGIDRSPGMVGRGTHRPVTLRVGDALSL
                     PFEESAFDAATIMFGLRNVVDPAAALREMARVVRPGGRLVVCEFSHPTWGPFRTVYLRY
                     LMGGLPRIARRVSSNPDAYTYLADTIRAWYDQPALASVIAGSGWTRVSWRNLTGGIVAL
                     HRAVRPACAAPDTAPLPQVAHA"
     gene            complement(6361..7530)
                     /gene="hppD"
                     /locus_tag="DQ392_RS16375"
                     /old_locus_tag="DQ392_16355"
     CDS             complement(6361..7530)
                     /EC_number="1.13.11.27"
                     /GO_function="GO:0003868 - 4-hydroxyphenylpyruvate
                     dioxygenase activity [Evidence IEA]"
                     /GO_process="GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hppD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016467185.1"
                     /locus_tag="DQ392_RS16375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16355"
                     /product="4-hydroxyphenylpyruvate dioxygenase"
                     /protein_id="WP_114016367.1"
                     /transl_table=11
                     /translation="MEPTALDTTEAAAGAPAAGAQGDARPWDVAGIDHIRLCVGNARQA
                     AHFYVSAFGMEITACRRPENSPQGHAEYVLTSGSVRFVVTGGGEPDSPATRWAALHGDG
                     VSDIALRVGNLDEGLVYAARAGARVLQEPTTARDEFGAVRTAAIATYGDLRHTLVERRS
                     YSGPFLPGFEAPSPGCPRPPGPRLFHRVDHLVGCVELGLLEEWVGFYRRTMDFSTMAEF
                     VEDDIATAYSALMSKVVTDGSQKVKLPLNEPAPGRRRSQIDEYLTYHRGPGTQHIALET
                     EDILAATDALRAAGVDFLPTPRAYYDDPVLRSRIGSVRVDIDELRSRGILVDRDEDGYL
                     LQIFTRPLVDRPTFFIELIERHGSQGFGKGNFKALFEAVEREQELRGNL"
     misc_feature    7588..7601
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.73"
                     /tool="antismash"
     misc_feature    complement(7631..7646)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.41"
                     /tool="antismash"
     gene            7693..8826
                     /locus_tag="DQ392_RS16380"
                     /old_locus_tag="DQ392_16360"
     CDS             7693..8826
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000031: Methylation (61% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016467184.1"
                     /locus_tag="DQ392_RS16380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16360"
                     /product="methyltransferase"
                     /protein_id="WP_281272999.1"
                     /transl_table=11
                     /translation="MTTAMTVPSEGPDAPAPTGPAELDMDRLSLLLFGHAAFQYLNAAC
                     ELRLLDLLMERGPLDATRIRSELGLAERAADILLLGCTSLGLIRKEEGRYQAAALIESL
                     AEEGSWSKLRDTVAFEAHIVYPGQEDFVDSLRENSNVGLRRVPGDHPDLYHRFSLHPHL
                     EAVFYRYMRSWSQLANAHLVAALDLHGATRLLDCGGGDAVNALALAAHHPHLEVTVLEI
                     PSSAPMTEKKISEAGLGERVSVQPCDMFADAFPGGMDCVLFAHQLVIWTPEENTALLRK
                     AHDALDPGGRVVIFNSMSNDEGDGPVVAALDSVYFASLPAEGGMIYPWRLHEECLRAAG
                     FTAIERVEVPGWTPHGIIVATKPAAEPATKPAAEQRA"
     misc_feature    complement(7722..7736)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.07"
                     /tool="antismash"
     gene            8823..9992
                     /locus_tag="DQ392_RS16385"
                     /old_locus_tag="DQ392_16365"
     CDS             8823..9992
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016467183.1"
                     /locus_tag="DQ392_RS16385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16365"
                     /product="prenyltransferase"
                     /protein_id="WP_114016368.1"
                     /transl_table=11
                     /translation="MSDAPGSSAPRPATASPAPGSFAAFVQLARVKFLFQSMMVTGFGV
                     TLAVHATGTFSLPWYLLTLAFAWSTHLMTHFCNEYFDLEADRANPRPTAWTGGSRVLVD
                     GLLTPATSIGAAFVLLFTSLALVLAMPTLPARLLAGGLTALAWFYTAPPLRLNYHALGE
                     ASCAAVLYAMGPLLAAVLQPGGPGALLWWCTGLVAALQVLRCLVMNLADIEGDALVGKA
                     TLAGVLGPRRVTHVYTAGQTLLYAGVLVLALTQVLPALVAAAQLLVAPVAGLVVRGLRT
                     DAMSDTGRSGGVTFWASMQLPLTTCATTLALLADLLSAGRPAPALWNAIAGGTALLFTA
                     WLYRAVAAARRPAHHEDTGSAAPVPPEPHASTKPRPLPVEPVREGREAR"
     gene            10001..11059
                     /locus_tag="DQ392_RS16390"
                     /old_locus_tag="DQ392_16370"
     CDS             10001..11059
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="DQ392_RS16390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16370"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_181856454.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.4e-61, bitscore:
                     202.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPPARAHEIAVSVCRRAHARLEPTLRTAVRTLPRQLSRMSGYHF
                     GWWGPDGEETGRAMPGKAVRPALAYLAAEALGAPAEQATPGAAAVELVHNFALVHDDIM
                     DGDSTRRGRPALWQQYGTGAALLAGDGLFALAADTLASPRTQRSCWALTLLTRSMLTTL
                     HGQAYDHDFTRAPWSGPGAVTLADYRRAASAKTGALLAAATAIGALLAGGGPREVARFA
                     RFGRGLGVAFQCADDVLGLWGEPSGTGKPVGTDLREGRRTLPLVAALTSGTTAGDRLHA
                     LLRRRSGGRLNAEELDTALELIEAAGGRAATEAEARRQQQAAVGAVAGLPMPARVRTEL
                     LATAHYVTARRT"
     gene            11056..12165
                     /locus_tag="DQ392_RS16395"
                     /old_locus_tag="DQ392_16375"
     CDS             11056..12165
                     /GO_function="GO:0009976 - tocopherol cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025608.4"
                     /locus_tag="DQ392_RS16395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16375"
                     /product="tocopherol cyclase family protein"
                     /protein_id="WP_114016370.1"
                     /transl_table=11
                     /translation="MSTPRRRDAPHRAAGLSASHHAPALRAAGLSASHHAPGLGVPESE
                     HMLRHRWWARLRRRWRATGADLPRGDPLPAHPAPMEGYLWRFTDPVGGRVLLLACGVNH
                     HPRRPWTTVVAAAHPGGLVRSASVEGTGADTTAYRIAAHPAIELTRDRLRARVGDEVDL
                     RCALRPYHTWPPRRFLHGSGVFSLVPGLDHYWHPHLFGATVEGTVRLRDRTWDLAGCQV
                     YAEKSWGRGFPRAWWWGQAHGFDRQDLCVAFAGGLLGRGRLTVPVGGLVVGIGGRTVSL
                     VPPGAWVRARVGDGSWHVSGRSPRYQIEMTGTAAGDRPLRLPVPLLDPYRFGHSLQHLS
                     GRLEVRIRRDGRLLYAGTSHLAGLETGGV"
     gene            12274..12399
                     /locus_tag="DQ392_RS35850"
     CDS             12274..12399
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQ392_RS35850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_281273000.1"
                     /transl_table=11
                     /translation="MREVEWYEETVPRWVGWARYLLLGIAVCALTAALLANWDAV"
     gene            complement(12436..12783)
                     /locus_tag="DQ392_RS16400"
                     /old_locus_tag="DQ392_16380"
     CDS             complement(12436..12783)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012738.4"
                     /locus_tag="DQ392_RS16400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16380"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_245981612.1"
                     /transl_table=11
                     /translation="MLTGLREVPEDAVRAAHGMGLTRRQILFRVELRLAVPSLISGLRV
                     TTVMTTGIVAIAAYVVDQGLGSLILKALQSPLHTQFIGAGALAVALALAADAALALLQR
                     LLVPRGLRTAR"
     misc_feature    complement(12553..12555)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12666..13445)
                     /locus_tag="DQ392_RS35240"
     CDS             complement(12666..13445)
                     /GO_function="GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020119.4"
                     /locus_tag="DQ392_RS35240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CocE/NonD family hydrolase C-terminal
                     non-catalytic domain-containing protein"
                     /protein_id="WP_245981544.1"
                     /transl_table=11
                     /translation="MEEPRLRAWMPDSAPVGSDRELRPGRWVTEPSWPAPGVAPQRTAL
                     SPWSDGPATAQLRSALPVGAASGDFLKFGDVPGQYGDQAAGDGRSHTFTGPVLEEGVEI
                     LGAPSVTLRVTADRPQAQLAVRLCEVFPDGPSKLVTTGLLNLTHRDGHAEPEPLEPGRA
                     YDVRVPLFAIGHRLRRGQPRQGLRLRVPVAVGVAVAGFSVLTVESRSSSTASICCSPRS
                     SPGCGRSPRTRCVRRTAWASPAGRSSSGSNCGSPSLR"
     gene            complement(13491..13820)
                     /locus_tag="DQ392_RS35245"
     CDS             complement(13491..13820)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQ392_RS35245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_245981546.1"
                     /transl_table=11
                     /translation="MATQTQVASEMLPWAATMLAYNARPGDPAVLGDAWRDARLERLEA
                     TGPYAHTWLAHQRRDAYWQHGSSARTSPRSKYPSTRSGAGSTPTGAPSSGCSNTSTRNT
                     PPPRR"
     misc_feature    complement(13810..13823)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.82"
                     /tool="antismash"
     gene            complement(13924..14631)
                     /locus_tag="DQ392_RS16410"
                     /old_locus_tag="DQ392_16390"
     CDS             complement(13924..14631)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018851174.1"
                     /locus_tag="DQ392_RS16410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16390"
                     /product="hypothetical protein"
                     /protein_id="WP_245981548.1"
                     /transl_table=11
                     /translation="MLIATPHAASADVGGGNVSVGWSIDNTPSSGMTNITFPVTVNPAT
                     AHKEGIYFAQQYSFADGMGYTGLQPRENSGSNERLSARFSTFTQGATTSDPLCHEGADG
                     GPGVTCAVDFDAVYGHRYDIKVERTGTDTWSGTATDTVTGEATHLGTYTLPAGSGDLQG
                     SQGGFVEYYLGVPSCAEMPRSDVVFGGPTSTDAGGLSGTSRANYEYSDCVGESGYQAEN
                     DGAGTHVTRGFVS"
     misc_feature    15575..15594
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 23.99"
                     /tool="antismash"
     gene            15915..16079
                     /locus_tag="DQ392_RS34475"
     CDS             15915..16079
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQ392_RS34475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_181856455.1"
                     /transl_table=11
                     /translation="MDAVAAFDRTPARSHPPLTTPLAGPGAPARTVTPGAARDGAGLDE
                     VWRSWATEL"
     gene            complement(16157..17437)
                     /locus_tag="DQ392_RS16415"
                     /old_locus_tag="DQ392_16395"
     CDS             complement(16157..17437)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127327.1"
                     /locus_tag="DQ392_RS16415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16395"
                     /product="low temperature requirement protein A"
                     /protein_id="WP_114016587.1"
                     /transl_table=11
                     /translation="MSDAQAPGTDEGSGPAHRLRPMTGRDPHESGRVSTPLELLFDLSF
                     VIAVGTAASHFAEMLAAGHPGEAVTAFVLAMFAISVAWISFSWFASAFGTDDWLYRALT
                     MVQMTGVVVFSLGLPAMFHSLEEGGHLELRVIVIGYVVMRVAMVAQWWRAARQSPPFHD
                     VGMANIRWTVLVQAGWIVVGFVPMPLAAAFGAFAVLAVGELVLPVLTQGEAGGTPWHPH
                     HVAERYSLFAIITLGEGVVGTVASSGGLLGGGDGTHWTGNAVAVVIAGVGLTFGMWWVY
                     FALPFGDILVHRRGRGYLFGYGHIPLFVGIAGAGAGLHVAGLQLEHDARIGEVAVVLSL
                     AVPVGLYLLMVYLLQTLLLSAVDRYHLLLISLTFVVLAVAVFLSAAGVALAVCLLVVML
                     APFVTVLGYETTGERHQRRMLEGLRTR"
     misc_feature    17502..17516
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            17557..17823
                     /locus_tag="DQ392_RS16420"
                     /old_locus_tag="DQ392_16400"
     CDS             17557..17823
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQ392_RS16420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DQ392_16400"
                     /product="hypothetical protein"
                     /protein_id="WP_114016372.1"
                     /transl_table=11
                     /translation="MGPASAVVMGSDLVARADARLDQLGRRLADDLELFTRLLYDTYHR
                     LGAADVSRALRRIQEIGWEVGAAFRTVDVLLSPTLAQPGAVVR"
     gene            17876..18169
                     /locus_tag="DQ392_RS16425"
                     /old_locus_tag="DQ392_16405"
     CDS             17876..18169
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012312.4"
                     /locus_tag="DQ392_RS16425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16405"
                     /product="MFS transporter"
                     /protein_id="WP_245981550.1"
                     /transl_table=11
                     /translation="MGPPSTSVPGRLFAGPPHACGGSSATAADKWGKKRGILLLGAVFV
                     AGSLVCACANSFPALLVGRALQGCLVGVVTMSYSLVRDIMPRDFVPLGLKPW"
     gene            18351..18764
                     /locus_tag="DQ392_RS16430"
                     /old_locus_tag="DQ392_16410"
     CDS             18351..18764
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012575.4"
                     /locus_tag="DQ392_RS16430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16410"
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_281273001.1"
                     /transl_table=11
                     /translation="MTTADDVRSIEADALPTRFARGWHCLGLARDFTDGKPHTVRAFGR
                     KLVVCAASDGTLNVLDAYCRHMGGALSRGTVEGDDIACPFHAWRWGGDGRCTRVPHARR
                     VPLRARTAASHRAAGRSAVRLERIRRASRLPRT"
     gene            18697..>18867
                     /locus_tag="DQ392_RS35855"
                     /pseudo=""
     CDS             18697..>18867
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039286.3"
                     /locus_tag="DQ392_RS35855"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="3-ketosteroid-9-alpha-hydroxylase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRQDGLLFVWNESGGQAASRGRDRPPRIAGATSDDWTDWSWYSVE
                     TKGANCREIIDN"
     gene            complement(19118..19603)
                     /locus_tag="DQ392_RS16435"
                     /old_locus_tag="DQ392_16415"
     CDS             complement(19118..19603)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471211.1"
                     /locus_tag="DQ392_RS16435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16415"
                     /product="hypothetical protein"
                     /protein_id="WP_114016588.1"
                     /transl_table=11
                     /translation="MPSPRTLLSIYLNDHLAGATAGTELLRRTAKTHRGRAAGSALEDL
                     AREVAEDRETLIGIMARLGVPVRRSRVRAGWLAEKAGRLKLNGSLTSRSPLSDVLELEA
                     MRFGVQAKMSCWRTLAGLTDSEPGLDGDALAALLDRADAQAKKLETLSGSAVSRVWG"
     gene            complement(19895..20581)
                     /locus_tag="DQ392_RS16440"
                     /old_locus_tag="DQ392_16420"
     CDS             complement(19895..20581)
                     /EC_number="5.1.3.9"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471474.1"
                     /locus_tag="DQ392_RS16440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_16420"
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="WP_245981613.1"
                     /transl_table=11
                     /translation="MPTARADALLAGVRGRLIVSCQAPPGDPLRSPAHIAAIAASVCAG
                     APVAGVRIQGVEDVEAVRAVVDLPLIGLWKDGADGVYITPTAGHARAIARAGADVVAVD
                     ATARPRPDGRPLAETVRAVHEAGKLFMADVSTLDEGLRAAALGADLISTTLSGYTADSP
                     QSSGPDLELVRALAPRVRVPVCAEGRLRTPADARAALDAGAWAAVVGTAITAPAALATR
                     FATALT"
ORIGIN
        1 ggcgctgtac gcgtgcgcgg acacctcggc ggtcggcagc ccgttgaaga accagaagcg
       61 ctcggcccgc cgggtgccga ccgaccgtac ggccgtgacg atgcggtgca tgagttcgac
      121 gtcgccgaag ccgtccttga ggccgaccac cgaggggacg tcgagcaggg agaccgcggc
      181 ggactcggtg aacaccccgg tggagcggtg gtagacgatc actggtgtcg acgtgtccgc
      241 cacggcgtac ctgacgaagt cgaccagccc gtcgggcggc ccggagacca ggtagggcgg
      301 caggagcagc acaccgtcgg ccccgccgtc ggccgcggcg gcgacccccg cgcgggcggc
      361 ggccgctccg cctcccgcgc ccacccacac cggcacgcgc ccgcgcacca cctcgcgcgc
      421 ccgtgccagt acggcggcgt gctccgcggg cgagagcgag ctgaactcgc ccgtcccgca
      481 ggccacgaac agcgcgccgg ctcccgcctc gacgtgtcgt tcgacgttct gggcgaaggc
      541 gtccaggtcg agggagaggg cgtcggagaa gggagtgagg gggaatgcca ggagcccttc
      601 gagcggggcc gggggctgtg ccatcgtgtc ctgctccttt cgtggacgag gaggtgccgc
      661 tcgtgaacga gaggtgccgc gccgggacgc cgcggtgggc tcgccgggcg atgcggggct
      721 cgccgggcag cgtcgtgggt gccgagcggt gacgggccgg ctgggagagg gcccgcgtcg
      781 tcgcgcggag cgggtcaggc cgggaggcgg gtctcctcgg ggcccggctc cgctgtgccg
      841 ggggtgtcat cgtctccgag gacctccatg agctcttcgg cggtttcgct gcgctcggga
      901 gcgagggcgc cgaggcccgc gtacagcacg agggacacca gcaccggtgt ggccaccagc
      961 caggtctgtg aggtgtcgat gacgtagtag acgagcccgt agccgacgag cccgcccgcc
     1021 caggaggtga gggccgcgcg cgggccgcag cggcggaacc aggggagcat gccgagcagc
     1081 agcgggatgg agatcggacc catcagtgcc gccacccagt tgacgacgag ttggagcacg
     1141 ccgccgaggt tctgggcctg tgtggcgacg accatggtca gtacgacgaa ggagaccgtc
     1201 gtcacgcgcg ccgcgaggag accctgcggt ggggtccagg cccgtgcctt gcggtacatc
     1261 accgggatca tgtcgcgggt gatgacggcc gagatcgcgt tggcgtcgga ggagaccatc
     1321 gccatggtgt gcgagaagat gccggcgagt acgaggccga tgagcccggg cggcaggaac
     1381 gtggtcgtca tgaccgcgta ggagttgtcg gggttgtcga cgtcggggac gagcagcgga
     1441 gcggcgaaca tcgggaacat cagcaccagg ggccacagca ggtacagccc ggcggagagc
     1501 cgggcgctcc gccgggccgc gtgggtgtcg ggcgcggcca tgtaacgctg cgccaggttc
     1561 cacatgcccc cgttgtactc cagggtcttc accaggacgt agaccatcag gaagaggccc
     1621 gtgtacttcg gcgtcgtcgg gtcgacgtgc ccggcgggca gcttgtccca catcgtccac
     1681 agcgccggga caccgccgag cttgccgagt acgacgacga gcatcacgat cgcggcgacc
     1741 gcctggatga cgaactggcc cagttccgtc agggcgtcgg cccacagccc gccgaccgtg
     1801 cagtagaaga gcgtgatcac gccggtcacg aggatgccga cgttgtagtc gatcccggcg
     1861 aagacgtgca gcaaggtggc gaccgcgaac cacttcgcgg cgatgtcgaa gatcttcagc
     1921 aggctgccgc tccaggccag cgcctgctgg gtggtcacgt tgtaccgcat ggccaggtac
     1981 tcgagcgggg aggccacccc cagtttcgag cgcagccggt tccaccgcgc cgcgaacagc
     2041 cagctgccga tgccgacacc cacgccgatg ctggcgaagc cccagaagta gaccgtgaca
     2101 cccgtggtgt aggcgaccga ggcgtaggcg acgaacagca ccgcgctgta gccggacatg
     2161 tggtgcgaga tgccggccag ccaccacggc atgcgtccgc ccgcggtgaa gaagtccttc
     2221 acgttcccga cccttttgtg cgaccaccag ccgatgagga ccatcagccc gaagtacgca
     2281 cacatcactg tccagtcaaa cgagtgcacc tctctggctc ccctccgtgt ccatcatcac
     2341 gatgtgtttc acgtacctga atgccatctc atgtgccgac ttggttcagt gctatgaatt
     2401 tgttcgggga acgtaatatg gtcgctccag cgcgtcaacg gtctcgacgc accaccgcgg
     2461 atccggccgt acgggcgcca acgggacgag gaggggcagg aatgctgcgg catgacggcg
     2521 cgtcagcagc gggcggcgcg gcacaggcag gcgcaccatc caccgaaccg tccggagtca
     2581 agtccgcttg gcggacggtg gaactcctgg aggcgttcgc agcgggagac gtctggctct
     2641 ccctgtcgga cctgcacgcc agcaccggct tcccccgctc cagcctgcac gggctgctgc
     2701 gcacactgct cgacgcgggc tggctggaac aggacggcgg caccacccgc taccggctcg
     2761 gcatccgcgc cctgaagtgc ggaaccgcct acctggaccg ggacgccgtc gtaccgttcg
     2821 ccaccgaggt actggaacag gtacgcgaac agaccggcta caccgcccac ttcgcccggc
     2881 gcaacggcga cgaggtcgtc tacctggaga cccgcgaggc ccagcgctcc acccacctgg
     2941 tctcccgcgt gggccgctcc ctgcccgtcc acgccaccgc gctgggcaag gccctcctcg
     3001 ccgagctgac ccacgacgag gtcgaagccc tcctgcccgc gacgctgccc gccctcaccc
     3061 cccgcaccct cacctcgcgg gaggcgctgc actccgcgtg cgccgagtcc cgggagctcg
     3121 gatacgcctc ggagcacgag gagggcacac cgggcatccg ctgcgtcgcc gccgtgatcc
     3181 cctaccgcat cccgggcacc gacgcgatca gctgctccat gcccgtggac cggaccgacg
     3241 acgcggagac ccggcgggtc ggcgaactgc tggccgaagc caccgcacag ctcgcccgac
     3301 gcctgcgccg cgaaggcatc cgctgacacg tccatcccgc cgcgcacggc tccgcgcaca
     3361 gaccgagacg tgcgaccgaa cgagacgccg cacagaccga gacgcgccag aggagaccga
     3421 gatgaacgac cagcgcctgc tgatcaccgg agcggccggc acggtcggca ccctgatgcg
     3481 cccccggctg cgccgcccgg ggcgtgtgct gcgcctcttg gacctcgccc cgcagcccgc
     3541 ggccgaacct ggcgaggcgg tggaactgct gaccggctcg gtgaccgacg ccgaggtgat
     3601 gaagagcgcc tgccaggatg tcgacgccct gatccacctg ggcggcctca gcagagagga
     3661 cacctgggaa gccaccctcg acgtcaacat cggcggcaca cacaccgtgc tcgacgccgc
     3721 ccgcgaggcc caggtgcccc gggtcgtcct ggcgtcgagc aaccacgccg tcggcttccg
     3781 caccacggac gagggcggtt ccgacgggct gccggcggac tcctcaccgc gccccgacac
     3841 ctactacggc gtcagcaagg ccgcgatcga ggccctgggc agcctctacc actcccgctt
     3901 cgggatggac gtcaccgcga tccggatcgg ctcgtgcttc gagacgccac tcccgctggg
     3961 cgaacgcggc ctgtccacct ggctgtcccc cgacgactgc gcccgcctcc tcgaagcgtg
     4021 cctggccacg acctccccgg gataccgcct catctggggc gtctcggaca acgcgcgccg
     4081 caccttctcg ctggccgaag ccgaggccct gggctacacc ccgcgggacg acgccgaggt
     4141 ctacgcgccg cgcctggccg caccgcccgc gcccgacggc accctcgcgg aactggtcgg
     4201 cggctcgttc tgcacggcac cgctggggcg gcacaacccg ctgtgacggc gcggcccctc
     4261 gctcagccgg gcacccggga ccggccaggc cggaccgacg gcgcccccgc gaaccggcgg
     4321 ccggcgtggt cggcgggtga gggcgtcacc cggatcagcg cgttgacgag gtggtccatc
     4381 gcatcggtgc ccggcctgtc ggtgaggttg gagagcagcc gcaccatgaa acgcatggcg
     4441 ccgggggacc gcacggcgtg ctgtgtgacg agcgaggtga aggcgggccg cgccatcagc
     4501 gccgagaagc cgcgcccgag gcggtagtac cggcccagcc ggtatgccat ctgggccggg
     4561 tagtgctcca gcgcccgctc ccgggcgggg cccgccgggc gggccagcgc ctggcccgcc
     4621 acgtcggcgg ccagttcggc cgactccatg gcgtaggtga tgccctcgcc gttgcacggg
     4681 ttgaccatgc cgccggcgtc accgatcagc aggagcccgt cgcggtagtg ggggaggcgg
     4741 ttgaacccca tcggcagggc ggcgccgcgc aggggtcctt ccgcgttgcc gggctcgcgc
     4801 agcccccacg ctgcgggggt acgggccagc cacgtctcca gcagcctgcg cgtctgtatg
     4861 gcgccggtgc gggagtcgtt gaggacgccg aggccgacgt tgaccctccc gtcgcccagg
     4921 ggaaagatcc agctgtatcc ggggaggatc cggccgtcct cgcggcgcag gtccaaccag
     4981 gactccagat acgggtccag gtgtctggcg ctgtggaagt agcgccgtac cgcggtgccc
     5041 acagggcgct tcctgagccg ttcgataccc atggaaacgg cgaggcgccc cgcgacgccg
     5101 tccgccgcga tcaccagcgg agcggcgaag tcgcgctccc gccctcccgg tccggccgtc
     5161 gagacgccca cgacacgccc ggcgcggtcc agcagcggac cggtgacctt cgtgcgggtg
     5221 tgcaggcggg cccccgcggc ctcggcgtgc cgggcgagga gctggtcgaa gtcctcgcgc
     5281 gtgcgggtga gcccgtacgc gggaaaggcg ctgcactcgg gccagtcgag ctccagggtc
     5341 cggccccggg agacgaaccg caggccccgg ttgcgcatcc agccgggggc cgaggtgtcg
     5401 atgcccatcc gcaccaactg gcgtacggcc cggggcgtca ggccgtcgcc gcagaccttc
     5461 tcgcggggga actccgactt ctccaggagc gccacggaca gtccctggcg ggccaggtgc
     5521 caggccgcgg tggagccgcc agggcccgca cccacgacga tcacctgcgc ccgctccgcc
     5581 gccggccggc tcacgcgtgg gccacctggg gcagcggcgc cgtgtcgggt gcggcgcagg
     5641 cggggcggac cgcgcggtgc agggcgacga tgccgccggt gaggttgcgc cacgagacgc
     5701 gcgtccagcc actgccggcg atcacggagg cgagggcggg ctggtcgtac caggcgcgga
     5761 tggtgtcggc gaggtaggtg taggcgtccg gattgctgga gacccggcgg gcgatccgcg
     5821 gcagaccgcc catcaggtac cgcaggtaca cggtgcggaa cggcccccac gtcggatggc
     5881 tgaactcgca gaccactagc cggccgccgg gccgcaccac cctggccatc tcgcggagcg
     5941 cggcggcggg gtccacgacg ttgcgcagcc cgaacatgat ggtcgccgcg tcgaacgcgg
     6001 actcctcgaa ggggagggag agggcgtcac ccacgcggag cgtgacgggc cggtgcgtgc
     6061 cccggccgac catcccgggc gagcggtcga tcccgacgac ggcggcgccc gagcgggcga
     6121 gggcctcggt ggacacgccc gtaccgcagg cgacgtccag gcagcgctcc ccgggccgca
     6181 ggcccagggc ctcgcgggtt cgggcccgcc acgtcctgtc cgctccggcg gacagcaggg
     6241 tgttggtcag gtcgtagcgc cgcgccgcct ggtcgaacat cgcggacacg gcgtcgggtt
     6301 gcttggcgag agtcgccctc ggcatcgctg ctcctgggga aacggtgtgc gaagtggggg
     6361 tcagaggttt ccgcgcagct cctgctcgcg ctcgacggcc tcgaagagcg ccttgaagtt
     6421 gcccttgccg aagccctggc tgccgtggcg ttcgatcagt tcgatgaaga aggtcggacg
     6481 gtccaccagg gggcgggtga agatctgtag caggtagccg tcctcgtccc ggtccaccag
     6541 gatgccgcgg gagcgcagct cgtcgatgtc gacgcgtacg gagccgatcc gcgagcgcag
     6601 cacgggatcg tcgtagtagg cgcgcggagt gggcaggaag tcgacaccgg cggcccgcag
     6661 ggcgtccgtc gcggcgagga tgtcctcggt ctccagggcg atgtgctggg tcccaggccc
     6721 ccggtggtag gtgaggtact cgtcgatctg ggagcggcgc cgtcctggcg ccggttcgtt
     6781 gagcgggagc ttgaccttct gcgagccgtc ggtgacgacc ttgctcatca gggccgagta
     6841 cgcggtggcg atgtcgtcct cgacgaactc ggccatcgtc gagaagtcca tggtgcggcg
     6901 gtagaagccg acccactcct ccagcagacc gagttcgaca cagcccacga ggtggtcgac
     6961 gcggtggaag aggcgcgggc ccggggggcg ggggcagccg ggggagggcg cctcgaagcc
     7021 gggcaggaag ggcccgctgt aggagcggcg ctcgaccagg gtgtgccgca ggtcgccgta
     7081 ggtggcgatg gccgccgtgc gcaccgcacc gaactcgtcc cgcgccgtcg tcggctcctg
     7141 gagcactcgg gcaccggcgc gggcggcgta cacgagcccc tcgtcgaggt tgccgacccg
     7201 gagagcgatg tcgctgaccc cgtcgccgtg cagcgccgcc caccgggtgg cggggctgtc
     7261 gggttccccg ccgcccgtca ccacgaagcg gacgctgccc gaggtgagca cgtactcggc
     7321 gtgtccctgc ggtgagttct cgggccgccg gcacgcggtg atctccatgc cgaaggccga
     7381 gacgtagaag tgggcggcct ggcgggcgtt tcccacgcac agcctgatgt ggtcgattcc
     7441 ggcgacgtcc cacgggcggg cgtcgccctg ggcgcccgcg gcgggggcgc ccgctgcggc
     7501 ttcggtcgtg tcgagtgccg tcggctccat ggtggcgtcc cctgcgttga ctacatgggc
     7561 tatcactata tgtgcctatg tgatgcgtat agtgactatt gaccttttca cgccgtttca
     7621 ccgatcgttc acgaacgcgc tttcgacatc gttcgctccg gtcgacgagc accgaacgcc
     7681 aagagggaaa ccatgaccac cgcgatgacc gtcccgtcgg aagggccgga cgcccctgcc
     7741 cccaccggcc ccgccgagct ggacatggac cggctgtccc tcctgctctt cgggcacgcg
     7801 gcgttccagt acctcaacgc cgcctgcgag ctgaggctgc tggacctgct catggagcgg
     7861 gggccgctgg acgccactcg gatcaggtcc gaactgggac tggccgagcg ggccgccgac
     7921 atcctgctgc tgggctgcac ctcgctgggg ctcatccgca aggaggaggg gaggtaccag
     7981 gcggcggcgc tgatcgagtc actggccgag gagggcagct ggagcaagct gcgggacacc
     8041 gtcgccttcg aagcgcacat cgtctacccg gggcaggagg acttcgtcga ctccctgcgc
     8101 gagaactcca acgtcgggct gcggcgcgtc cccggcgacc accccgacct gtaccaccgc
     8161 ttcagcctcc acccccacct ggaggcggtg ttctaccggt acatgcgctc ctggtcccag
     8221 ctggccaacg cacacctcgt cgcagcgctc gacctccacg gcgccacccg gctcctcgac
     8281 tgcggcggag gcgacgccgt caacgcgctc gccctggccg cacaccaccc ccacctcgag
     8341 gtgaccgtcc tggagatccc ctcctcggcc ccgatgacgg agaagaagat ctccgaggcg
     8401 gggctgggcg agcgcgtctc ggtacagccg tgcgacatgt tcgccgacgc ctttcccggc
     8461 gggatggact gcgtcctctt cgcccaccag ctggtcatct ggacgcccga ggagaacacc
     8521 gcgctgctgc gcaaggccca cgacgccctc gaccccggcg ggcgtgtcgt catcttcaac
     8581 tcgatgtcga acgacgaggg cgacggcccc gtggtggcgg ccctggacag cgtctacttc
     8641 gcctccctgc cggccgaggg aggcatgatc tacccgtggc ggctgcacga ggagtgcctg
     8701 cgcgcggccg gtttcaccgc gatcgaacgc gtcgaggtac cagggtggac gccccacggc
     8761 atcatcgtcg ccaccaagcc cgccgccgag cctgccacca agcccgccgc cgagcagcgc
     8821 gcatgagcga cgcgccgggc agcagcgcac cgcggccggc aaccgcctca ccggcgcccg
     8881 gctcgttcgc cgccttcgtc caactcgcca gggtcaagtt cctcttccag tcgatgatgg
     8941 tgaccggctt cggcgtgacc ctcgccgtcc acgcgaccgg caccttttca ctgccctggt
     9001 acctgctgac gctggcgttc gcctggtcga cgcacctgat gacccacttc tgcaacgagt
     9061 acttcgacct ggaggccgac cgggccaacc cgcggccgac cgcctggacg ggcggcagcc
     9121 gcgtcctcgt cgacgggctg ctcacccccg ccaccagcat cggcgccgcg ttcgtcctgc
     9181 tgttcacctc gctggctctc gtcctggcga tgcccacgct gcccgcccgg ctgctggcgg
     9241 gcgggctgac cgcgctcgcc tggttctaca cggcaccgcc cctgcggctg aactaccacg
     9301 cgctgggcga ggcgagctgc gcggccgtcc tgtacgcaat gggccccctc ctcgccgccg
     9361 tcctgcaacc cggcggaccc ggcgcgctgc tctggtggtg cacgggcctc gtcgcggcgc
     9421 tccaggtgct gcgctgcctg gtgatgaacc tcgcggacat cgagggtgac gccctcgtgg
     9481 gcaaggccac cctggccggc gtgctcggcc cccgcagggt cacccacgtc tacacggcgg
     9541 gccagaccct tctgtacgcc ggcgtgctcg tcctggcact cacccaggtg ctgcccgcgc
     9601 tggtggccgc cgcgcagctg ctggtcgcac cggtcgcggg cctggtggtg cgcgggctgc
     9661 gcaccgacgc gatgtccgat accgggcgct cgggcggcgt caccttctgg gcgtccatgc
     9721 aactgccgct caccacctgc gcgaccacgc tcgccctcct cgccgacctg ctgtcggccg
     9781 ggcggccggc tcccgcgctc tggaacgcca tcgcgggcgg aaccgcgctg ctgttcaccg
     9841 cgtggttgta ccgcgctgtc gccgccgccc ggcgtcccgc acaccacgag gacaccggga
     9901 gcgcggcgcc cgtgcccccg gagcctcacg cgtccacgaa accgcgcccg ctgccggtgg
     9961 agcccgtacg ggaggggcgc gaggcgcgat gagcgcaccg gtgagtcccc cggcgagggc
    10021 tcacgagatc gccgtttcgg tctgccgacg ggcgcacgcg cggctggagc ccacgctgcg
    10081 cacagccgtg cgcaccctgc cgcgacagct gtcccggatg agcggctacc acttcggatg
    10141 gtggggaccc gacggggagg agaccggccg cgccatgccg ggcaaggccg tccgcccggc
    10201 actggcctac ctcgcggcgg aggcgctggg cgcgcccgcc gagcaggcca cccccggggc
    10261 cgccgctgtc gaactcgtcc acaacttcgc cctcgtccac gacgacatca tggacggcga
    10321 ctccacccgc aggggccggc ccgcgctgtg gcagcagtac ggcacggggg cggcgctgct
    10381 ggcaggagac ggcctgttcg cgctcgcagc cgacacgctg gcctcgccgc gtacccagcg
    10441 gtcctgctgg gccctcaccc tgctgacccg ttccatgctc accaccttgc acggacaggc
    10501 gtacgaccac gacttcaccc gggccccctg gagcggcccc ggcgccgtga ctctcgcgga
    10561 ctaccgccgt gccgcgtccg ccaagacggg cgcgctgctg gcggcggcca ccgccatcgg
    10621 ggcgctgctg gccgggggcg ggccgcggga ggtggcacgg ttcgcccggt tcggccgcgg
    10681 gctcggcgtg gccttccagt gcgccgacga cgtcctcggc ctgtggggcg agccgtccgg
    10741 caccggcaag ccggtcggca ccgacctgcg cgaaggccgc agaaccctgc ccctcgtcgc
    10801 ggcgctcacc tccggcacca cggcaggtga ccggctgcac gccctcctgc ggcgtcgctc
    10861 cggtggacgg ctgaacgccg aggagttgga caccgccctg gagctgatcg aggccgcggg
    10921 cggccgggcc gcgaccgaag cggaggcacg ccgccaacag caggcggccg tcggcgcggt
    10981 ggccggcctg ccgatgcccg ctcgcgtccg caccgaactg ctcgccaccg cgcactacgt
    11041 gacggcacga cggacatgag cacgccccgc cgccgcgacg ccccgcaccg cgccgccggt
    11101 ctctccgcct cgcaccacgc cccggcgctc cgcgccgccg gcctctccgc ctcgcaccac
    11161 gcacccgggc tcggcgttcc ggaaagcgag cacatgctgc gtcaccgctg gtgggcgagg
    11221 ctgcgccgcc gctggcgggc cacaggagcc gacctgcccc gcggtgaccc cctgcccgcg
    11281 cacccggccc ccatggaggg atatctgtgg cgcttcacgg acccggtcgg cgggcgcgtc
    11341 ctgctcctgg cctgcggtgt caaccaccac ccgcgacgcc cctggaccac ggtcgtcgcc
    11401 gcggcgcacc ccggcggcct ggtgcgctcg gccagcgtcg agggaaccgg ggccgacacc
    11461 accgcctacc gcatcgccgc gcaccccgcg atcgagctga cccgcgaccg gttgcgggcg
    11521 cgcgtcggtg acgaggtcga tctccggtgc gcgctgcgcc cgtaccacac ctggccaccg
    11581 cgccgcttcc tgcacggcag cggtgtcttc tccctcgtcc cgggactcga ccactactgg
    11641 cacccccacc tgttcggcgc cacggtggag ggcacggtgc ggctgcgcga ccggacctgg
    11701 gacctggccg gctgccaggt ctacgcggag aagtcctggg ggagaggctt tccgcgcgcc
    11761 tggtggtggg gccaggccca cggcttcgac cgccaggacc tgtgtgtcgc cttcgcggga
    11821 ggtctgctgg gccggggcag gctgaccgtg cccgtgggcg gcctcgtcgt cggtatcggc
    11881 ggaaggacgg tgagcctggt cccacccggg gcgtgggtgc gggccagggt cggggacggc
    11941 agctggcacg tgagtggccg ctcaccgcgc taccagatcg agatgaccgg cacggccgcg
    12001 ggcgaccggc cgctccggct gcccgtgccg ctgctcgacc cgtatcgttt cggccattcc
    12061 ctccagcatc tgtcaggacg gctggaggta cgcatccgcc gcgacggacg cctgctctac
    12121 gccgggacct ctcacctcgc cggactggag acgggaggag tgtgaacggg gaggggcgcg
    12181 ggcccgcggg tgccgtcttc ggatcggatg acaatcgcat aacgggaggg tggtggggcg
    12241 ttgccgcgag ccccgcgcgt cgttggtagc ggcgtgagag aagtcgagtg gtacgaagaa
    12301 acggttcctc gttgggtggg gtgggcgcgg tacctcctgc tcggcatcgc ggtctgcgcc
    12361 ctcacagcgg cgctgctggc gaactgggac gcggtctgaa caaccgcgtc acccgccgcc
    12421 gggaggcggc ccacctcagc gcgcggtccg caggcccctc ggaacgagga ggcgttggag
    12481 gagtgcgagg gcggcgtcgg cggccagggc gagggcgacg gcgagcgcgc cggcgccgat
    12541 gaactgggtg tgtaagggcg actggagcgc cttgaggatc agcgagccga ggccctggtc
    12601 gacaacgtag gcggcgatgg cgacgatccc ggtcgtcatg accgtcgtca cccgcagccc
    12661 cgagatcagc gaagggacgg cgagccgcag ttcgaccctg aagaggatct gccggcgggt
    12721 gaggcccatg ccgtgcgccg cacgcaccgc gtcctcgggg acctcccgca gcccggtgag
    12781 gatcgtggtg aacagcagat agaggctgta gaggacgagc gcgattccac ggtgagcacg
    12841 gagaaaccgg cgacggccac acccacggcc acagggacgc ggagacggag accctgacgc
    12901 ggttgcccgc gccgaaggcg gtgcccgatg gcgaacagcg gtacccgcac gtcgtaggcg
    12961 cggccgggct ccaacggctc gggctcggcg tgcccgtcgc ggtgggtgag gttgagcagc
    13021 cccgtggtga ccagcttcga cgggccgtcg gggaagacct cgcacagccg caccgccagc
    13081 tgcgcctgcg gccggtcggc ggtgacgcgc agcgtgacgg agggcgcgcc gagaatctcg
    13141 acgccctcct ccagcacagg gccggtgaac gtgtgcgagc gtccgtcgcc ggctgcctgg
    13201 tccccgtact ggccgggaac gtcaccgaac ttgaggaagt cgcctgacgc ggcgccgacc
    13261 gggagcgcgg agcgcagctg cgccgtcgcc gggccgtcag accaggggct cagcgcggtg
    13321 cgctgcggcg cgacacccgg tgcgggccag gacggttcgg tgacccagcg cccggggcgc
    13381 agctcgcggt cgctgcccac cggcgcggag tcgggcatcc aggcgcgcag ccggggttct
    13441 tccatgtccc ggctcggcct ggtgcgggta ggtgtgcgcc cacgggccga tcagcgcctt
    13501 ggcgggggcg tgttccgggt cgaggtgttc gagcagccgg aagacggcgc cccggtaggg
    13561 gtcgagccgg cccccgaccg cgtagacggg tacttggatc gcggagaagt cctcgcagac
    13621 gacccgtgct gccagtaggc gtcgcgccgc tggtgggcga gccacgtgtg ggcgtaaggg
    13681 ccggtcgcct ccagccgctc cagccgcgcg tcgcgccacg cgtcgccgag caccgcgggg
    13741 tcgcctggcc gggcgttgta ggcgagcatc gtcgccgccc acggcagcat ctcggaggcc
    13801 acctgtgtct gcgtggccat gcatgcccgc gccgggcggc ccggagcgga atccgaaccc
    13861 ggtcccgaac cgcgaagccg cccgccggag gctcggcggg cggcttcgcc gacagctcgc
    13921 gactcaggag acgaagcccc gcgtcacatg cgtgccggcg ccgtcgttct cggcctggta
    13981 gccggactcg ccgacgcagt cgctgtactc gtagttggcc ctggaggtac cgctcaggcc
    14041 gccggcgtcc gtggaggtcg gacccccgaa gaccacgtcg gatctgggca tctcggcgca
    14101 gctggggacc ccgaggtagt actccacgaa gcctccctgg gaaccttgga gatcgccgct
    14161 cccggccggc agcgtgtacg tccccaggtg ggtggcctcg ccggtgaccg tgtccgtcgc
    14221 cgtgccgctc caggtgtcgg ttcccgtccg ctcgaccttg atgtcgtagc ggtgcccgta
    14281 cacggcgtcg aagtccaccg cgcaggtgac accgggaccg ccgtcggccc cctcgtggca
    14341 gagcgggtcg gaggtggtcg cgccttgtgt gaaggtggag aagcgggcgg acaaccgctc
    14401 gttcgagccg ctgttctccc gcggttgcag accggtgtag cccatgccgt ccgcgaagct
    14461 gtactgctgg gcgaagtaga tcccttcctt gtgggccgtg gccggattga cggtgacggg
    14521 gaaggtgatg ttggtcatcc ccgaggacgg cgtgttgtcg atcgaccagc cgaccgacac
    14581 gttgccgccc ccgacatccg cggacgccgc gtgcggcgtc gcgatcagca aagcggcagc
    14641 cgccgctgcg ggtagcgcac aacggcggag tgtcccgact actgacatgt gcttcctcat
    14701 ctctgtgggg gagagggaga cctgtgtgag ggagagggaa accgcgcttt ccgaaaccgg
    14761 cggttccctg gtctgtgaaa gccctgggaa acgctgttcg gatctcggcc gtccgccctc
    14821 gcggaattct ctactcggct cccgacggcg actccatgga ctaacgcggc cctccccttg
    14881 gactcccggg ggacgccgcg ccgacggccc gacgagaagg ggcgggatgc ggacggcccc
    14941 gggacggcgc gccgcgccga taaccagtgg cgcgggcggg gcgggcagga agggtgggac
    15001 gaacgaggcg ccggaggcgc cgggttcgac gacggctgag gtgtccggcc atgccgagtt
    15061 ccaaggagag ctatggaatc gccccggcgc gccgggtggg cgccggcgaa ctgcggatgg
    15121 atgctcggcg gtttcgccgg ggtcacggcc gcacccgaac tccttccccg ctgggccgtg
    15181 cccctttgct ggctcgtcta cctcgcggtg ctggcggcat tgatgagtcg cctggcacaa
    15241 cgtatgggtc tcctcctggt gataccgctc gtcgcgtatc tcgcggccct ttacttcctg
    15301 tgcgtcgtcg aactgcgcgc cgatattctg atgcgcgtac gcggacaact cgtccacacg
    15361 gtggtgaccg gggaacgggt gacctccccg cgcggatacc tgatccgtca ctacaccctt
    15421 tcccggcccg acggctcacc ggtggcagga ggcgagatcg acgacggcac cgtgctggaa
    15481 cgcggccggc atctgacggt ctacgaggac cccggggcga gatccagccc agcaccccgg
    15541 ggcacaccga cccgaggacc cgcgccgtgt tcgcaggggg actgctggcc ctcgcgaccg
    15601 gggcggtcgt ctgggcggcg tactcccgct cactggaacg cctcgccgac gacccgaagg
    15661 accgagggct gtgagctcac gctcgtccgc cgacatgctc ccgtaggcga tcggcggacg
    15721 tggtgtccac gtcttccccg ccgaggacgc gggcggtggt cacgcccccg gctgggacgc
    15781 tgcgcggaac gcggaggcag cgtgcgttcc gcgacccgcg tcctgcacga gggcagggag
    15841 ctgttcgtcg aggagcttga cccgacggac cacgaggaac gtcagctgcc ggggtcctcg
    15901 gcggctcacg ggtcgtggac gcggtcgcgg ccttcgaccg tacccccgcc cggtcgcacc
    15961 cgcccctgac gacaccgctg gcaggccccg gcgccccggc ccgcaccgtg acacccggcg
    16021 ctgcccgcga cggcgcgggc ctcgatgagg tgtggcgctc gtgggccacc gagctgtgac
    16081 gcgtgccggc cacccgctca ccggcacacg cgactgcgcc cgccgagcgc gcgtgtgcgt
    16141 ccgcgccgcc ccggggtcac cgcgtacgga ggccctccag catccgtcgc tggtggcgct
    16201 cgccggtcgt ctcgtagccg agcacggtga cgaagggggc gagcatcacc acgagcaggc
    16261 acaccgcgag cgcgacgccc gccgcggaca ggaacaccgc gacggccagc accacgaacg
    16321 tgagggagat cagcaacagg tggtagcggt ccaccgccga cagcagcaac gtctgtagca
    16381 agtagaccat cagcaggtag aggccgaccg gcaccgcgag ggagagcacg accgcgacct
    16441 caccgatgcg cgcgtcgtgc tccagttgca gtccggccac gtgcagtccg gcgccggctc
    16501 ccgcgatgcc gacgaagagc gggatgtgcc cgtagccgaa gaggtaaccg cggccgcggc
    16561 ggtggaccag gatgtcaccg aagggcaggg cgaagtagac ccaccacatg ccgaacgtca
    16621 ggccgacacc ggcgatgacg acagcgaccg cgttcccggt ccagtgggtc ccgtccccgc
    16681 cgccgagcag accgccggag gaggcgacgg tgccgaccac tccttcgccg agcgtgatga
    16741 tcgcgaaaag gctgtaccgc tccgccacat ggtgcggatg ccagggggtg ccgccggcct
    16801 cgccctgggt gaggaccggc agcaccagtt cccccaccgc cagcaccgcg aaggcgccga
    16861 acgccgcggc gagcggcatg ggtacgaacc cgacgacgat ccagcccgcc tggacgagca
    16921 cggtccagcg gatgttcgcc atgcccacgt cgtggaaagg gggcgactgc cgggccgccc
    16981 gccaccactg cgccaccatc gcgacgcgca tcacgacgta gccgatgacg atcacccgca
    17041 gctccaggtg cccgccctcc tcaagggagt ggaacatcgc gggcaggccg agggagaaca
    17101 cgacgacgcc ggtcatctgc accatcgtca gtgcccggta gagccagtcg tcggtgccga
    17161 aagcggaggc gaaccagctg aagctgatcc acgcgacgct gatcgcgaac atcgcgagca
    17221 cgaacgcggt gaccgcctct cccgggtgtc ctgccgcgag catctcggcg aagtgggagg
    17281 cggcggtgcc caccgcgatc acgaagctga ggtcgaacag cagctccagg ggcgtggaga
    17341 cccggccgct ctcgtgcggg tcgcggccgg tcatcggccg caggcggtgg gccggcccgc
    17401 tcccttcatc cgtaccaggg gcttgcgcat cactcatacg cagcatggtg acgcaagcgg
    17461 aggtgtcggg gcggtctcgc caccgcggcg gcccgcctgt gcgagcgtct cggccacgag
    17521 gtcaccgagc tcaccgcccc gtacagaacg gccgaggtgg gccccgcgtc ggccgtggtg
    17581 atgggaagcg acctggtggc cagggccgac gcccgactgg accagctcgg ccggcggctc
    17641 gccgacgacc tcgaactctt cacgcgcctg ctctacgaca cctaccaccg cctgggcgcc
    17701 gccgacgtga gccgggcgct gcggcggatc caggagatcg gctgggaggt gggcgccgcc
    17761 ttccggacgg tcgacgtgct gctgagcccg acgctcgcac agcccggtgc ggtggtgcgc
    17821 tgatcgtccc ggtggctggg acagagccga ggggatcttc cgtggtgtgt ctcacttggg
    17881 gcccccttcc acgtcggtcc ccggacgtct ttttgcgggc cccccgcacg cgtgcggcgg
    17941 ctcgtcggcc acggcggcgg acaagtgggg caagaagcgg ggcattctcc tgctcggagc
    18001 cgtcttcgtc gccggcagcc tcgtctgcgc gtgcgcgaac tcattcccgg cgctgctggt
    18061 gggacgggca ctccagggct gtctcgtcgg cgtcgtcacc atgtcctaca gcctcgtgcg
    18121 ggacatcatg ccgcgcgact tcgtacccct cgggctgaaa ccgtggtgac ctgcgggtcg
    18181 ctggcggcca aggacctcgt cggctgagcg cggccggctg actcgccggg tgccgctcgg
    18241 ccgtcggata ccgctgagtg ggaccgtccc gctgtgcacg ccaccgcact gttcaactcg
    18301 acccgcacac tgtgccgaag cggtcgcttc ggcggaaggg aaggccaccc atgaccaccg
    18361 cggacgacgt tcgctccatc gaggcggacg cccttccgac gcgcttcgcc cgtggctggc
    18421 actgcctggg actcgcgcgt gacttcaccg atggaaagcc gcacaccgtc cgggcgttcg
    18481 ggcggaaact ggtcgtctgt gccgcctcgg acggcaccct caacgtgctc gacgcctact
    18541 gccggcacat gggcggcgcc ctgtcacgcg gcacagtgga gggcgacgac atcgcctgcc
    18601 cgttccacgc gtggcgctgg ggcggagacg ggcgctgcac ccgcgttccg cacgcccggc
    18661 gtgtaccgct gcgcgcacgg acggcggcgt cccaccgtgc ggcaggacgg tctgctgttc
    18721 gtctggaacg aatccggagg gcaagccgcc tcccgaggac gtgaccgccc cccccgtatc
    18781 gcgggtgcga cgagcgacga ctggacggat tggtcctggt actccgtcga gaccaagggg
    18841 gcgaactgcc gcgagatcat cgacaacgtg gtggacatgg cgcacttctt cacgtgcact
    18901 actcgttccc cacgtacttc aagaacatct cgccggcacc ggggctgcct ccggcgaggg
    18961 cggcgcgggc accgtccgac ggcgggcgct tcggcgacgc acggaccgac gccccgctcc
    19021 tcgaccggct ggtggccgtc acccctgacc ccgccaggga aggggcgccg ccgccccgcg
    19081 acgccgtcga acacccggcg cgggagccgc aggcgcctca gccccacacg cgcgacaccg
    19141 cgctcccgct caacgtctcc agcttcttgg cctgcgcgtc cgcccggtcg agcagggcgg
    19201 cgagggcgtc gccgtccagg ccgggctcgc tgtcggtgag accggccagc gtccgccagc
    19261 aggacatctt ggcctgtacg ccgaagcgca tcgcctccag ctccagcacg tcgctgagcg
    19321 gcgagcggga cgtcaggctg ccgttcagct tcaaccgtcc ggccttctcg gccagccacc
    19381 ccgcccgtac ccgggaccgc cggacgggaa cgcccagccg cgccatgatc ccgatgagcg
    19441 tctcgcggtc ctcggcgacc tcacgggcca ggtcctccag cgcggagccc gcggcccggc
    19501 ccctgtgggt cttcgccgtg cggcgcagca gctcggtgcc cgcggtggcc ccggcgaggt
    19561 ggtcgttgag gtagatactc aggagcgtac gcggtgacgg catggcacct tcctggagct
    19621 gacaggacgc ggacgggcgc ctcggccggt ggccggtggg ctatggcagg ggccgccggc
    19681 catggcctca ggcccgtggc ctgcggtgag gcaccgagag ctgacttccc ccgcggcccg
    19741 agcgccatgt cccctccctc cgcggtcact cgaccggtgg ccccgccgag cgcggcccgg
    19801 caggtggcgg acacgggcgc caccgcgtgc ggccccgtgg aagacacggc agaggcagac
    19861 cgcgtggctc acctcagcgc cgtgccgcgt gggctcacgt gagagccgtc gcgaagcggg
    19921 tggccagcgc ggcgggtgcg gtgatggccg tgccgacgac ggcggcccag gctccggcgt
    19981 cgagggcggc acgcgcgtcc gccggtgtgc gcagccgccc ttcggcgcag acgggcaccc
    20041 gcacgcgggg cgccagcgcg cggaccagct ccaggtcggg cccggaggac tgcgggctgt
    20101 ccgcggtgta accggacagg gtggtggaga tcaggtcggc gccgagcgcg gcggctcgaa
    20161 ggccctcgtc cagcgtggag acgtcggcca tgaagagctt gcccgcttcg tggacggcgc
    20221 ggaccgtctc ggcgaggggg cgtccgtccg ggcgggggcg cgcggtggcg tcgacggcga
    20281 ccacgtcggc accggcgcgt gcgatggccc gtgcgtggcc ggcggtcggg gtgatgtaga
    20341 cgccgtcggc gccgtccttc cacaggccga tgaggggcag gtccacgacg gcgcggacgg
    20401 cctcgacgtc ctcgacgccc tggatgcgga cccccgccac gggggcaccc gcgcagacgg
    20461 aggcggcgat cgcggcgatg tgggcggggg agcgcagcgg gtctccgggc ggtgcctggc
    20521 aggagacgat cagccggccg cgcacccccg cgagcagggc gtcggcgcgt gcggtgggca
    20581 tcgtggtgcg gctcggcggt gcgctgccgg tcgcgggctc gctcatggtg cgtcctttgt
    20641 cgacgagggg gtgcgtgggt gtgcggtgcc gcccgggccg gtcgccctgg cgggctcctc
    20701 ccgcaggagg gcggcggcgc cgacgacggc cgcgcgggga ccgagggcgg ccggcacggg
    20761 acggaggcgg gagggacccg gcagcagctc ggcggcgaat gcctcggtca gcggacgcca
    20821 gaacggtgcg ccgacggagg cgactccgcc gccgatcacc acccgctcgg ggtcgagggt
    20881 gttgaccagg cccgccagcg cacggcccag cgcgcccgcc ccctgagcga gtacttcacg
    20941 ggccgtcgcg ctctcctcct cgccctgacg gctgccgcct tgcccgccac ctccagcctg
    21001 ggcaccctct gccgcctctc cggccagtgc cgccacgtgc cgcaggtcga ccgggtgtg
//
