LOCUS       NZ_QOIM01000026        21479 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces reniochalinae strain LHW50302
            NODE_14_length_245591_cov_21.3765_ID_27, whole genome shotgun
            sequence.
ACCESSION   NZ_QOIM01000026
VERSION     NZ_QOIM01000026.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces reniochalinae
  ORGANISM  Streptomyces reniochalinae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 245591)
  AUTHORS   Li,L.
  TITLE     Streptomyces reniochalinae sp. nov. and Streptomyces diacarnus sp.
            nov. from marine sponges
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 245591)
  AUTHORS   Li,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUN-2018) Department of Pharmacy, Ren Ji Hospital
            School of Medicine, Shanghai Jiao Tong University, Pujian, Pudong,
            Shanghai 200127, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-FEB-2016
            Assembly Method                   :: A5-misseq v. MARCH-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003323735.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 01:54:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,751
            CDSs (total)                      :: 6,669
            Genes (coding)                    :: 6,475
            CDSs (with protein)               :: 6,475
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 4, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 66 of 194
            Pseudo Genes (incomplete)         :: 154 of 194
            Pseudo Genes (internal stop)      :: 16 of 194
            Pseudo Genes (multiple problems)  :: 41 of 194
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:03:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 89178
            Orig. end                         :: 110657
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QOIM01000026.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21479
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21479
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21479
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11479](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11479)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(167..1762)
                     /locus_tag="DQ392_RS08145"
                     /old_locus_tag="DQ392_08130"
     CDS             complement(167..1762)
                     /NRPS_PKS="Domain: AMP-binding (33-425). E-value: 2.1e-90.
                     Score: 295.2. Matches aSDomain:
                     nrpspksdomains_DQ392_RS08145_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049391.1"
                     /locus_tag="DQ392_RS08145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08130"
                     /product="AMP-binding protein"
                     /protein_id="WP_114014840.1"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-90, bitscore:
                     297.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSLTPSTGEATYRRLVEEHRWSVPARYNMAADVADRHPGDKLA
                     LIFEDHTGHREEVTWQRVQDRSRQIAAELHRTGVRKGDRVAVLLPQRTDTPATYLGVLR
                     TGAVLVTMSLLWADEPIRYRLADSGATVLVTETAALERAGGFSGTVVNVDDPAIGALPR
                     EFDTADTAPDDPALIFYTSGTTGAAKGIVHAHRTLLGHNEFRYCHDLRPGDVFYGAGDW
                     AWSMAKLMGPLRAGAVHLVHRPAGGFDPEGLLAAMSRNRVTTALVNPTFLRKMMQAVPD
                     AGSRYPQVLRVVCCSNEPLTPELIEWFRAQFGVTPLDYYGSTESYPLLGNFPGVPVKPG
                     SMGRPLPGWDVALLDADDREVPVGEPGEICLRAGSNPQYPLGYWNRPEAAAETFGGTWY
                     RTKDQAVMDEDGYFWFLGRTDDVIKTSGYRVGPYEVEAVLRDHPAVAEAGVVGVPDPVR
                     GQAVKAWIELTPGYEPSEALAREISDFARAAHSRFAYPRLVEFADELPRSATGKIQRGA
                     LRARDTSPADPDAA"
     CDS_motif       complement(455..520)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS08145_0003"
                     /evalue="3.90E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="DQ392_RS08145"
                     /protein_end="436"
                     /protein_start="414"
                     /score="19.4"
                     /tool="antismash"
                     /translation="FLGRTDDVIKTSGYRVGPYEVE"
     aSDomain        complement(488..1663)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS08145_AMP-binding.1"
                     /evalue="2.10E-90"
                     /label="DQ392_RS08145_AMP-binding.1"
                     /locus_tag="DQ392_RS08145"
                     /protein_end="425"
                     /protein_start="33"
                     /score="295.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DVADRHPGDKLALIFEDHTGHREEVTWQRVQDRSRQIAAELHRTG
                     VRKGDRVAVLLPQRTDTPATYLGVLRTGAVLVTMSLLWADEPIRYRLADSGATVLVTET
                     AALERAGGFSGTVVNVDDPAIGALPREFDTADTAPDDPALIFYTSGTTGAAKGIVHAHR
                     TLLGHNEFRYCHDLRPGDVFYGAGDWAWSMAKLMGPLRAGAVHLVHRPAGGFDPEGLLA
                     AMSRNRVTTALVNPTFLRKMMQAVPDAGSRYPQVLRVVCCSNEPLTPELIEWFRAQFGV
                     TPLDYYGSTESYPLLGNFPGVPVKPGSMGRPLPGWDVALLDADDREVPVGEPGEICLRA
                     GSNPQYPLGYWNRPEAAAETFGGTWYRTKDQAVMDEDGYFWFLGRTDDVIKT"
     CDS_motif       complement(581..679)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS08145_0002"
                     /evalue="9.40E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="DQ392_RS08145"
                     /protein_end="394"
                     /protein_start="361"
                     /score="11.7"
                     /tool="antismash"
                     /translation="PVGEPGEICLRAGSNPQYPLGYWNRPEAAAETF"
     CDS_motif       complement(1178..1237)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DQ392_RS08145_0001"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="DQ392_RS08145"
                     /protein_end="195"
                     /protein_start="175"
                     /score="17.8"
                     /tool="antismash"
                     /translation="ALIFYTSGTTGAAKGIVHAH"
     gene            complement(1855..2655)
                     /locus_tag="DQ392_RS08150"
                     /old_locus_tag="DQ392_08135"
     CDS             complement(1855..2655)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (21-261). E-value: 9.2e-55. Score:
                     177.5. Matches aSDomain:
                     nrpspksdomains_DQ392_RS08150_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049392.1"
                     /locus_tag="DQ392_RS08150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08135"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_114014841.1"
                     /transl_table=11
                     /translation="MTETSSTVIVDEHPVQGASTQTFVAEVTLNRPEKLNAWTGPMREE
                     LIAALETLGADEKCRAVVLTGAGRAFCAGQDLAETAAIDPDDHAAAAAWIDDFGRLFRV
                     LRGLEKPTVAAVNGVAAGSGFQFALLADLRIGHAEVKMGQPEVLSGIPSITGIWAMRGI
                     LGRAKTTEFALTGRLVDGTEAQRLGLLSRLVAADEVRAEALAEAARLAEFPPGAVALTK
                     GRIRELDDAGLDEAIAAAKKVHTAAYATGEPQREMARFLAGRRR"
     aSDomain        complement(1873..2592)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DQ392_RS08150_ECH.1"
                     /evalue="9.20E-55"
                     /label="DQ392_RS08150_ECH.1"
                     /locus_tag="DQ392_RS08150"
                     /protein_end="261"
                     /protein_start="21"
                     /score="177.5"
                     /tool="antismash"
                     /translation="TFVAEVTLNRPEKLNAWTGPMREELIAALETLGADEKCRAVVLTG
                     AGRAFCAGQDLAETAAIDPDDHAAAAAWIDDFGRLFRVLRGLEKPTVAAVNGVAAGSGF
                     QFALLADLRIGHAEVKMGQPEVLSGIPSITGIWAMRGILGRAKTTEFALTGRLVDGTEA
                     QRLGLLSRLVAADEVRAEALAEAARLAEFPPGAVALTKGRIRELDDAGLDEAIAAAKKV
                     HTAAYATGEPQREMARFL"
     gene            2844..3806
                     /locus_tag="DQ392_RS08155"
                     /old_locus_tag="DQ392_08140"
     CDS             2844..3806
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049393.1"
                     /locus_tag="DQ392_RS08155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08140"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_114014842.1"
                     /transl_table=11
                     /translation="MELRHLRYFAVLAEELHFGRAADRLHMAQPPLSQRIRDLEREMGV
                     RLFDRTRHRVQLTEAGALLLEYVRPVLVGVDSAREAMRRIRPGEAGVLRVGVPPDTTPV
                     VLPTLTAGLTRRVPDVLIDLHELTTDEQLSRLREGELDAGVVRHPSDTIGLESGPVARR
                     ELGVVLPADHPLAAGTGTASRAVRMRDLDGAPLVIFPRAMAPRLYDHMLTICRDEGFLP
                     GSIRHARNPNFVQGLVLAGRGVHLNEPPGTPLPDGLVWRRLEGAPLAWLTSVVWVPSRH
                     NETIAAFTEAVSEGLAAAGHHMEDPAASAPAVFEPPASG"
     gene            3973..4668
                     /locus_tag="DQ392_RS08160"
                     /old_locus_tag="DQ392_08145"
     CDS             3973..4668
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471433.1"
                     /locus_tag="DQ392_RS08160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08145"
                     /product="HAD family phosphatase"
                     /protein_id="WP_245981261.1"
                     /sec_met_domain="HAD_2 (E-value: 2.1e-32, bitscore: 106.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPSARPAVVFDLDGTLVDSEPHYYEAGRQLLAAHGVPHFSWEE
                     HSRFIGIGTRETLETLRRVHGLTTPVDELLAEKNRLYLQLAHSGTEVFPEMRKLVERLH
                     SAGVPLIVASGSSRAAIDAVLGATSLDALLPLRVSAEEVAHGKPEPDVFLEAARRLDAE
                     PADCVVLEDATPGAEAAHRAGMRCVAIPYVPATAEDPAFAKAGLLFAGGQRAFDAQETY
                     DWITGGTSL"
     gene            4824..6239
                     /locus_tag="DQ392_RS08165"
                     /old_locus_tag="DQ392_08150"
     CDS             4824..6239
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433738.1"
                     /locus_tag="DQ392_RS08165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08150"
                     /product="hypothetical protein"
                     /protein_id="WP_114014844.1"
                     /transl_table=11
                     /translation="MGAHTAERDSRLSFWLRVREFAVPPSMIVTATARRLSGDWAGACA
                     AAHIDVDLDLRSVARIRGGELAARLRNDLRHLAPDLLRWHMPRIAPDGLLRPGLTLTLA
                     RYDAAGPDGAGPVHLVARTPPAWADAGQRFSIALWDGSRSGPDAPAGIRHHPHPGPHRR
                     FRLDLHRHLWDVRSTDALPTRSGADRPPTDRGCDSGPELPGVGPWRHHCPVDRWAAEAD
                     ILLRGEGRPAGAVTVRLGARRRLVLNLRPDDDGTGRPARLRSATATDGSVSSLPVLPEA
                     ATWTLPDLALLRAGLVEAGRLHPLVASALVPDRSPTGSPVATEQPDGSQVVECRGAQHR
                     IGLVDGVLTPLDHDPSEIRREELLAALSGTPLPCLQAIDRAHLKPECLAGVRERLDHGD
                     NAGALAAVESLLGPEAVLRSGALRDELEAAAQRRITHKLFREGLVGAGPRRDHPKRRRS
                     PDHRSHPRDATFY"
     gene            6393..7670
                     /locus_tag="DQ392_RS08170"
                     /old_locus_tag="DQ392_08155"
     CDS             6393..7670
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018560160.1"
                     /locus_tag="DQ392_RS08170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08155"
                     /product="MoxR family ATPase"
                     /protein_id="WP_114014845.1"
                     /transl_table=11
                     /translation="MPTCTPSDAALAPSHPAGASQLDVAGELLTLLRDRTTEPRPDTQL
                     EALTLAVAADLPVLLWGEPGIGKTASLTQLARALDLPLTTVIASVHEPSDFSGLPVVGA
                     DPAEEGIPMAPPDWAVRLVRAGRGLLFLDELSTAPPAVQAALLRLVLERRIGALRLPPG
                     VRIVAAANPRSSAADGWELSAPLANRFVHLHWVHDPETVVRGLGGTWPRATLPRLDPEK
                     LPEAVDFARRAVCGLLSARPGLVHRLPGNETRRGGAWPSPRSWETAVRMVAFATAAGSS
                     REVLSLLVRGAVGDGPGLELMASLDRMDLPNPETLLADPSGALLPERGDLRQAVLDGVV
                     QAVRNRPDKSRWDAAWTLLVRAVETGAPDLVVVPANTLAALRRDDWDVPESIGRLAGAV
                     TLSQRADHAAERAAQRAAGVTARPGR"
     gene            7667..8926
                     /locus_tag="DQ392_RS08175"
                     /old_locus_tag="DQ392_08160"
     CDS             7667..8926
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018560159.1"
                     /locus_tag="DQ392_RS08175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08160"
                     /product="VWA-like domain-containing protein"
                     /protein_id="WP_114014846.1"
                     /transl_table=11
                     /translation="MTAAAPEALDLDKLFAARLHAARSRPYLATALFALHTVESRQAPT
                     MAVDRHWRCYASPAFVDRTPVEELAGVWVHEVSHLLRDHHGRSDRYAREHGATGPAEHL
                     RMNIAADCEINDDAFGDGLARPEGAVGPGALGLPDGELMEDYLRQFRLGPRTQSMAWLD
                     CGSGADGQEREWDLGPGGAHGLSEQEREAVRFRVARGITARPGRTSKGWRRWAQEVVHP
                     PQPWRELLGAAVRSAAPGSGASEDYTYGRPSRRSAGVPGVVLPSLRRRPPRVSVVIDTS
                     GSVDDTELGSALLEVAAISRALGGRRDLVSVLPCDAAARVVHPLCHAEGIPLLGGGGTD
                     LRTGFTQALRARPRPDVLVILTDGQTPWPDTRPPCRTVVGLFPRGYGNRSWDEDDPDHV
                     PDTPPAWARVVDIGSAPAVG"
     gene            complement(9102..9986)
                     /locus_tag="DQ392_RS08180"
                     /old_locus_tag="DQ392_08165"
     CDS             complement(9102..9986)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743708.1"
                     /locus_tag="DQ392_RS08180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08165"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_245981262.1"
                     /transl_table=11
                     /translation="MTSTELTTAQGAHAFVPSPASPYQGDIARYWDQEARPVNLRLGEV
                     DGLYHHHYGIGDVDHAALGDAGDSGYEQRLIAELHRLESAQTEVLLDHLGRVGRDDMLV
                     DAGCGRGGSMVLAHQRFGCEVRGVTLSAKQADFANQRAIELGIEDHVQARVCNMLETPF
                     DSGQAAASWNNESSMYVDLHDLFAEHARILAAGGRYVTITGCWNPRYGQPSKWVSQINA
                     HFECNIHSRREYLRAMADNRLVPQAVIDLTGATLPYWELRATSSLVTGIEEAFINSYKD
                     GSFQYLLIAADRV"
     gene            complement(10001..11479)
                     /locus_tag="DQ392_RS08185"
                     /old_locus_tag="DQ392_08170"
     CDS             complement(10001..11479)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240846.1"
                     /locus_tag="DQ392_RS08185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08170"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_114014848.1"
                     /sec_met_domain="T1TS (E-value: 3.6e-69, bitscore: 228.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDPGSSPQQSSTPAAAARAAAAPADEAESGEDALLTLPGPPSFP
                     SPFPAVRETAQEIPGSAPVTESAPAHRAVPESAPVPVPAPGRDDGTGGETTARGGEPNS
                     RCTEEDAAAARHARQASSVLERILCGPSGPGTSSLRPGRREVSPACGVSEGSSVFGASD
                     PPAQGEPVPGLYYHPVPEPDAARVGEVSRRIKRWAVDEVQAYPPEWEEEFDGFSVGRYM
                     VACHPDAPTIEHLMVATRLMVAENAVDDCYCEDHGGSPIGLGSRLLLAHTALDPLHTTG
                     EYEAEWVESLQSDAPRRAYRSAMEYFVRKASPSQADRYRHDMSRLHLGYLAEAAWAQAE
                     HVPEVWEYLAMRQFNNFRPCPTITDTVGGYELPADLHARPAVQRVIALAGNATTLVNDL
                     YSYTKELKSPGTHLNLPVVIAEREGLSEKDAYLKAVEVHNDLMHTFEAEAAALAAACPV
                     PSVLRFLRGVAAWVDGNHYWHQTNTYRYSLPDFW"
     misc_feature    11800..11815
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            complement(11801..12286)
                     /locus_tag="DQ392_RS08190"
                     /old_locus_tag="DQ392_08175"
     CDS             complement(11801..12286)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981785.1"
                     /locus_tag="DQ392_RS08190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08175"
                     /product="MSMEG_6728 family protein"
                     /protein_id="WP_114014849.1"
                     /transl_table=11
                     /translation="MQTFLPHPEFAASAAVLDMRRLGKQRVETLQVLRGLTVPGYGWRN
                     HPAVRMWAGYEEALVRYGLEMCHVWTDSGRADTCAGTMMRDFAALEDFADPPRGYAELA
                     AADELPNWLGDSAFHRSHQSALVTKDPSFYRTHFPDVPEGLPYVWPASDRRRRVTDV"
     gene            complement(12485..13543)
                     /locus_tag="DQ392_RS08195"
                     /old_locus_tag="DQ392_08180"
     CDS             complement(12485..13543)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004949674.1"
                     /locus_tag="DQ392_RS08195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08180"
                     /product="beta family protein"
                     /protein_id="WP_114014850.1"
                     /transl_table=11
                     /translation="MSGPLYVPVLPARPHAVAAYRRLRPDVRAALMPLWNLPPLPAVGS
                     ARLEAAVRKFVAPVSGVHRHHDGWIDAPFAEDAQISGLADALSAYSELGRLRPVTGPER
                     TEAQQTAAVEVARRCGCGVGVRVRVATEWDGGTAEAVRMLLARACSTVPVDLMLDMSSV
                     LGDRPGAGKEALRALDALFALAPWRTAAVLGGGFPRVTGDMLEQGLREEPRTDWHMWSE
                     IRASGRTYLPSLGYGDYGVQPVGALAQVPQPDRKGGPPWGFLRYTTGNAFLLCKVLTRG
                     TERIAVNRRAARQILGLPEFREATGGAGEHWLRACADGPATSGRGTGGPTEWLWVGNVQ
                     HMTYVVRCLSGS"
     gene            complement(13671..14093)
                     /locus_tag="DQ392_RS08200"
                     /old_locus_tag="DQ392_08185"
     CDS             complement(13671..14093)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766657.1"
                     /locus_tag="DQ392_RS08200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08185"
                     /product="secondary thiamine-phosphate synthase enzyme
                     YjbQ"
                     /protein_id="WP_114014851.1"
                     /transl_table=11
                     /translation="MTDALRTHVLRVSTGSSETVHDLTRDCETFLADAARGRDGLLNVF
                     VPHATAGIAILETGAGSDDDLLAALRDLLPPDDRWRHRHGSPGHGRDHVLPALVPPHAT
                     LPVLSGSLELGTWQSICLVDTNGDNPSRQVRLSFLG"
     gene            14165..15319
                     /locus_tag="DQ392_RS08205"
                     /old_locus_tag="DQ392_08190"
     CDS             14165..15319
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105260.1"
                     /locus_tag="DQ392_RS08205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08190"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_114014852.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.7e-17, bitscore:
                     55.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METVEAVVIGAGQAGLSSAYHLRRTGFVPGTDFVVLDHSPAPGGA
                     WQFRWPTLTYGRVHGMHALPGMELTGADPGRPSAEVIGEYFRAYEHAFGLRVRRPVDVR
                     EVREIGEAGHGGRLLVQTSDGDWSTRTVINATGTWDRPFWPRVRGQELFLGRQLHTAQY
                     PGPGADAFVGRRVVVVGGGTSAVQHLMEIAEVARETVWVTRRPPLFRTGEFGPQEGRAA
                     VALVEERVRQGLPPQSVVSVTGLPMTEELRRARERGILERRPMFSSVTADGVQWDDGSR
                     AAADTILWATGFRPAVDHLAPLRLRESGGGIRLDGTRAVRDPRVHLVGYGPSASTIGAN
                     RAGRAAVREVRDLLTATAGPSDTDASASQATHVTPAAQTAPAAA"
     misc_feature    complement(15379..15392)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.42"
                     /tool="antismash"
     gene            15604..16356
                     /locus_tag="DQ392_RS08210"
                     /old_locus_tag="DQ392_08195"
     CDS             15604..16356
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1261: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471408.1"
                     /locus_tag="DQ392_RS08210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08195"
                     /product="(Fe-S)-binding protein"
                     /protein_id="WP_114014853.1"
                     /transl_table=11
                     /translation="MRVALFVTCINDALYPRTGQAVVALLERLGVEVDFPDAQSCCGQP
                     QFNTGYRHATEPLVERYADAFEGYDHIVVPSGSCAAMVRDNYPRIGAKAAAEGRGRVLS
                     AAAERVVPRTYELTEFLVDVLGVTDVGAYYPHTVTYHPTCHGLRMLGLGERPRRLLEQV
                     EGLQLRELEGAEECCGFGGTFAVKNAAVSSAMGADKARHIEASGAGSVCTVDNSCLMHI
                     GGVLSRSGSRVRPVHLAEILASTREAPL"
     gene            16389..16595
                     /locus_tag="DQ392_RS08215"
                     /old_locus_tag="DQ392_08200"
     CDS             16389..16595
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQ392_RS08215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DQ392_08200"
                     /product="hypothetical protein"
                     /protein_id="WP_114014854.1"
                     /transl_table=11
                     /translation="MADEVRPLVNEAAPEPGWSSGTTGERVRVRTGGTDAGHARHAESA
                     VRVDKASRASESGVTSESSREAR"
     gene            16592..18157
                     /locus_tag="DQ392_RS08220"
                     /old_locus_tag="DQ392_08205"
     CDS             16592..18157
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0019516 - lactate oxidation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359084.1"
                     /locus_tag="DQ392_RS08220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08205"
                     /product="lactate utilization protein B"
                     /protein_id="WP_245981263.1"
                     /transl_table=11
                     /translation="MSVTYLGMPPFPQAAQDSTRDTRLRGNLRHATHTIRDKRAGAVAE
                     LTDWAALRTAGAQIKDRTLRHLDTYLEQLEAAVTAAGGTVHWAVDAAEANEIVTRLVRE
                     TGEREVVKVKSMATQEIGLNEALEDAGIAAYETDLAELIVQLGDDRPSHILVPAIHRNR
                     GEIRDIFAERMGRWGRPAPDGLGDSPAQLAEAARLHLREKFLNAKVGISGANFMVAESG
                     TLVVVESEGNGRMCLTLPETLISVVGIEKVVPTWQDLEVFLQLLPRSSTAERMNPYTST
                     WTGSADGDGPRSFHLVLLDNGRTDTLADQVGRQTLRCIRCSACLNVCPVYERAGGHAYG
                     SPYPGPIGAILTPQLDSVETGLDASLPYASSLCGACYEVCPVAIDIPEVLVHLRERVVQ
                     GGTVTVRGQRTTVRPAKGHAAERAAMRAASWTFDHPRALRAGERLASRARRLVPNRLPG
                     PGSAWTDTRDTPRVPPESFRDWWRRTRTPAGAAGKSGGESVRQEGRPETPGGRDRQEGS
                     DEQP"
     gene            18144..18800
                     /locus_tag="DQ392_RS08225"
                     /old_locus_tag="DQ392_08210"
     CDS             18144..18800
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004935504.1"
                     /locus_tag="DQ392_RS08225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08210"
                     /product="LUD domain-containing protein"
                     /protein_id="WP_114014855.1"
                     /transl_table=11
                     /translation="MSSRETVLGRVRRALADVPRGERPDEAPVGRDYLRVHGERSPGET
                     VRLLREHLTDYRARVHHCSPASLPETVAELLARQGSRSVVTPAGVPGAWLPQDLEHVAD
                     SPALTPHDLDAVGSVVTGCAVAVAETGTLVLDASRDQGRRSITLVPDHHVCVVRVPDQV
                     VGSVPQALERLDPARPQTWISGPSATSDIELNRVEGVHGPRTLDVVLVGEESSMF"
     misc_feature    complement(18931..18945)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.68"
                     /tool="antismash"
     gene            18954..19547
                     /locus_tag="DQ392_RS08230"
                     /old_locus_tag="DQ392_08215"
     CDS             18954..19547
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359086.1"
                     /locus_tag="DQ392_RS08230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08215"
                     /product="hypothetical protein"
                     /protein_id="WP_114014856.1"
                     /transl_table=11
                     /translation="MSHSPISAPHTVAPAGPAEPGFRPDAPVNRPLLMVVMLSAAALSA
                     LSAILSASMVYLGGKDLADQNVRNAVDSDPSAVGLPADTRSADLKRMSPTAWDDVVTHW
                     QDTMSARAAFAVALALLVLLCALLARNASLWSRAALSVAVLLGGAFPHVLVLRDAPPTG
                     LYATSLAAPALAVVTVVLCWLPPVGRYAKARSRS"
     gene            19799..20605
                     /locus_tag="DQ392_RS08235"
                     /old_locus_tag="DQ392_08220"
     CDS             19799..20605
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471404.1"
                     /locus_tag="DQ392_RS08235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_08220"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_114014857.1"
                     /transl_table=11
                     /translation="MNQPAPRQVASIEGVGVRRMTSDQVILDGIDWSVRAGEHWALLGA
                     NGAGKTTLLKLIGAVMHPTSGTVEVLGNRLGRVDVRELRAHIGHVSTSQRVPQDAPAHT
                     VVLTGATGTVQPLWRKYDDETRQLAHDLLSELECKELADRPFGVCSGGQRARILIARAL
                     MPAPSLLLLDEPFNALDLPSREDLIDALRRLAADRPALATVTVTHHLEELPPTTSHALL
                     LREGRVGACGPVGDVLTGELMTRCFGRPIDVTHQDGRWLARSGHRS"
     misc_feature    21089..21102
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.14"
                     /tool="antismash"
ORIGIN
        1 acgcgccgga gtcgaaccac tcgacgaagt tgccgacggc ggtggccgcg gtgaccttgc
       61 gccgcacccc gctctcctcg gcggggtcgg ccgtctgctt ggcggggggt tcctgcggtg
      121 ccggaatcca gcggtccgtc gtcatgtccg tcgtcctcct ggtcggctac gcggcgtcgg
      181 ggtcggcagg gctggtgtcg cgtgcgcgca gcgcgccgcg ctggatcttt ccggtcgccg
      241 agcgcggcag ttcgtcggcg aactcgacca gtcgcgggta ggcgaaccgg gagtgcgcgg
      301 cgcgggcgaa gtccgagatc tcccgtgcga gcgcctcgct cggctcgtat ccgggagtca
      361 gctcgatcca ggccttgacg gcctggccgc gcaccgggtc cggcactccg acgacgcccg
      421 cctcggcgac cgcgggatgg tcccgcagca ccgcctccac ctcgtagggt ccgacgcggt
      481 atccggacgt cttgatgacg tcgtcggtgc ggccgaggaa ccagaagtag ccgtcctcgt
      541 ccatcacggc ctggtccttg gtccggtacc aggtgccgcc gaacgtctcg gcggcggcct
      601 cgggccggtt ccagtacccc agcgggtact gcgggttcga cccggcgcgc aggcagatct
      661 cgccgggttc tccgacgggc acctcgcggt cgtccgcgtc cagcagcgcg acgtcccagc
      721 cgggcagggg ccggcccatc gagcccggct tgaccggaac gccggggaag tttccgagca
      781 gcgggtacga ctcggtggag ccgtagtagt ccagcggggt cacgccgaac tgggcgcgga
      841 accactcgat gagttccggg gtgagcggct cgttggagca gcacaccacg cgcagcacct
      901 gcgggtagcg actgcccgcg tccgggacgg cctgcatcat cttacgcaag aaggtcgggt
      961 tgaccagggc cgtcgtgacc cggttgcggg acatcgccgc cagcagcccc tccgggtcga
     1021 agccgcctgc cggccggtgg acgaggtgga cggcgcccgc acgcagcggc cccatcaact
     1081 tggccatgga ccaggcccag tctccggcac cgtagaacac gtcgccgggc cgcaggtcgt
     1141 ggcagtaccg gaactcgttg tgcccgagca gggtgcggtg ggcgtgcacg atgcccttgg
     1201 cggcgccggt ggtgccggag gtgtagaaga tgagcgccgg gtcgtcgggc gctgtgtccg
     1261 cggtgtcgaa ctcacgcggc agcgcgccga tggcgggatc gtcgacgttg acgaccgtgc
     1321 cggagaaacc gccggcacgc tccagcgcgg cggtctcggt caccaggacg gtggcgcccg
     1381 agtcggccag cctgtaccgg atcggttcgt cggcccacag cagggacatc gtcaccagga
     1441 cggcccccgt gcgcagcacg ccgaggtagg tggcgggggt gtcggtgcgc tgcggcagca
     1501 gcaccgccac ccggtcgccc ttgcggacgc cggtcctgtg cagctcggcg gcgatctgcc
     1561 gcgagcggtc ctggacccgc tgccaggtca cctcctcgcg gtggccggtg tggtcctcga
     1621 agatcagcgc gagcttgtct ccggggtgcc ggtcggcgac gtcggccgcc atgttgtagc
     1681 gcgcgggcac gctccaccgg tgttcctcga cgagcctgcg gtaggtggcc tccccggtgg
     1741 acggggtgag gctggtactc atgggggtgg gggttcctct catacagatg agcgcgaccg
     1801 gtctcgggga tgactgcgcc ctgtgcggca accggtgccg ggcggcgagt tcggtcagcg
     1861 gcggcggccg gccaggaagc gggccatctc gcgctgcggc tcgcccgtcg cgtaggcggc
     1921 cgtgtgcacc ttcttggccg cggcgatcgc ctcgtcgagc cccgcgtcgt ccagctcgcg
     1981 gatccggccc ttggtgagag cgaccgcgcc gggcgggaac tccgcgagcc gggcggcctc
     2041 ggccagcgcc tccgccctga cctcgtccgc ggcgacgagc cggctgagca gtccgagccg
     2101 ctgggcctcg gtgccgtcca cgagccgccc cgtgagcgcg aactccgtgg tcttcgcccg
     2161 gccgaggatg ccccgcatgg cccagatgcc ggtgatgctg gggataccgg agagcacttc
     2221 cggctggccc atcttcacct cggcgtgacc gatgcgcaga tcggccagga gcgcgaactg
     2281 gaaccccgat cccgcggcca ctccgttgac ggcggcgacg gtgggcttct ccagccctcg
     2341 cagcacgcgg aagaggcggc cgaagtcgtc gatccacgct gcggccgcgg cgtggtcgtc
     2401 cgggtcgatg gcggccgtct ccgcgagatc ctggccggcg cagaaggccc ggcccgcgcc
     2461 ggtgaggacc accgcgcggc acttctcgtc ggcgcccagc gtctcgagcg ccgcgatcag
     2521 ctcctcgcgc atcgggccgg tccatgcgtt gagcttctcc gggcggttga gcgtcacttc
     2581 cgcgacgaag gtctgggtgg acgcgccctg taccgggtgc tcgtcgacga tgacggtgct
     2641 gctcgtctcg gtcatggaag aaggtgcctt tctccgggtg tgcccacgcg gcgacggacg
     2701 cgccgcagcg cacggtgaat cggggatggg ggcgcatcgc ccgtgaacgg gcgtcccgtg
     2761 agcagtcatg caagcagcgc gggtcgggcc ccggccaaca ccaatgcgga ccctcggtga
     2821 tatcgcagcg atatggtccg gccatggaac tccgtcacct gcgctatttc gccgtgctgg
     2881 ccgaggaact gcacttcggc agagccgcgg accggctgca catggcccag ccgccgctgt
     2941 cgcagcgcat ccgcgacctg gagcgcgaga tgggggtacg actgttcgac cgcacccggc
     3001 accgcgtcca gctcaccgag gcgggtgcgc tgctgctgga gtacgtcagg ccggtactgg
     3061 tcggggtgga cagcgcccgt gaggcgatgc gccggatccg gcccggggag gcgggggtcc
     3121 tgcgggtggg cgtaccgccc gacaccacgc ccgtggtgtt gccgacgctg accgcgggcc
     3181 tcacccgccg ggtgccggac gtcctgatcg acctgcacga gctgaccacg gacgagcagc
     3241 tttcccggct gcgagagggg gagttggacg cgggcgtggt ccgccacccc tcggacacga
     3301 taggtctgga atccggcccg gtggcgcggc gtgagctggg tgtcgtcctg ccggcggacc
     3361 acccgctggc agccggcacg ggcaccgctt cccgcgcggt gcgcatgcgg gacctcgacg
     3421 gcgcaccgct ggtcatcttc ccccgcgcga tggcaccccg gctctacgac cacatgctca
     3481 ccatctgccg cgacgaaggg ttcctccccg gttccatccg ccacgcccgc aacccgaact
     3541 tcgtccaggg gctcgtgctg gccgggcggg gtgtccatct gaacgagccc cccggcacgc
     3601 ccctgcccga cgggttggtc tggcggcggt tggagggggc gccgctggcc tggctcacgt
     3661 cggtcgtctg ggtcccgagc cgccacaacg agaccatcgc cgccttcacc gaggccgtgt
     3721 cggagggact ggccgcggcg ggtcaccaca tggaggaccc tgctgcttcc gcgccagctg
     3781 tgttcgagcc gcccgcctcg ggctgagtcc gggagtgtga agggctgacg cgctggagtg
     3841 ctgaggcact gacgggttga ggcgttcaag gggtgacgcg ctgggggccg cacccccccc
     3901 gggcttgcct cgacagggct gcgccgaggc cgggcccgac cgccttgccc agggtttggc
     3961 atgctggagc gcatgagcag tccctccgcc cgcccggcgg tcgtcttcga cctcgacggc
     4021 acactcgtcg acagtgagcc gcactactac gaggcgggca ggcaactcct ggccgcgcac
     4081 ggcgtgcccc acttctcctg ggaggagcac tcacggttca tcgggatcgg cacccgggag
     4141 accctggaga ccctgcgccg cgtgcacggg ctgacgactc cggtggacga gctgctggcg
     4201 gagaagaacc gcctctacct gcaactggcg cactcgggca cggaggtgtt cccggagatg
     4261 cggaaactgg tcgagcgcct gcactccgcc ggcgttccgc tgattgtcgc ctccgggtcg
     4321 tcgcgcgccg ccatcgacgc cgtcctcggt gcgacgagcc tcgatgccct gctgccgctg
     4381 cgcgtctcgg ccgaggaggt ggcgcacggc aagccggagc cggacgtttt cctggaggcc
     4441 gcgcgcaggc tggacgccga gccggccgac tgcgtggtcc tggaggatgc cacgcccggc
     4501 gctgaggcgg cacaccgtgc cggtatgcgg tgcgtcgcca ttccctacgt ccccgcgacg
     4561 gcggaagacc cggccttcgc gaaggcgggt ctgctgttcg cgggcggaca gcgcgcgttc
     4621 gacgcccagg agacctacga ctggatcacc ggcgggacct cactctgacc gtccgggacg
     4681 cgccggtctc gtcaccggcc tggagcaggt tccgcggggg cggaaaacgc gtggcgcgcc
     4741 gcggagacgg gcggtacggt ctcggcgatg acttcgcatt cttctgaggg attggaggtc
     4801 ctgtccgcgc aaggtgagtg ctgatgggcg ctcataccgc ggagcgggac tcccggcttt
     4861 ccttctggct gcgcgtgcgc gagttcgccg tgccgccctc catgatcgtt accgctaccg
     4921 cccgccgcct gtccggggac tgggcggggg cgtgcgccgc cgcgcacatc gacgtcgacc
     4981 tcgacctgcg ttccgtggcc cgtatccggg gcggggaact cgccgcccgc ctcaggaacg
     5041 acctgcgtca cctggcgccc gacctgttgc gctggcacat gccgaggatc gctcccgacg
     5101 ggctgctacg gccgggactg acgctcacgc tggcccgtta cgacgccgca ggccccgacg
     5161 gcgcgggccc cgtgcacctg gtggcgcgga ccccgccggc ctgggccgac gccggccagc
     5221 gcttcagcat cgccctgtgg gacggttccc ggtccggccc cgacgcgccg gcgggtatcc
     5281 gccaccatcc gcaccctggg ccccaccggc gcttccgcct cgatctgcac cgtcacctgt
     5341 gggacgtacg aagcaccgac gctctgccga cccggtcagg agccgaccgg ccacccaccg
     5401 accgcggctg cgacagtggc ccggagcttc ccggggtggg gccgtggaga caccactgcc
     5461 cggtcgaccg ctgggcggcc gaggcggaca tccttctgcg tggcgaggga cggcccgcag
     5521 gcgccgtcac cgtacggctc ggggcgcggc gccgcctggt cctgaacctc cgcccggacg
     5581 acgacggaac cggacgcccc gcgaggttgc gcagcgccac ggcaacggac ggcagcgtct
     5641 cgtccctgcc ggtcctgccc gaggccgcca cctggacact gcccgacctc gcgctgctcc
     5701 gtgccggcct cgtcgaagcc ggccggttgc acccactggt cgcctcggcg ctggtacccg
     5761 atcgctcgcc gacaggctcg cccgtggcca cggagcagcc ggatgggtcc caggtcgtgg
     5821 agtgccgggg cgcacagcac cggatcggcc tcgtcgacgg ggtactgacc ccgctggacc
     5881 acgatccgtc cgagatccgg cgtgaggagt tgctggccgc actgagcgga acgcccctcc
     5941 cctgcctcca ggccatcgac cgggcccacc tcaagcccga gtgtctcgcc ggcgtccgcg
     6001 aacggctcga ccatggcgac aacgccggtg cgctggccgc cgtcgagagc ctgctgggtc
     6061 ccgaggcggt gttgcggagc ggcgccctgc gggacgagct ggaggcggcc gcgcagcggc
     6121 gcatcaccca caaactgttc agggagggcc tggtcggagc cggtccccgc cgcgaccacc
     6181 cgaagcgtcg ccgctcgccc gaccaccgct cgcacccccg cgacgcgacc ttctactgac
     6241 ccgagccccg cccgctcccg cctcgcttct cccttgcccg cacgcccgcc cccgagggcg
     6301 cctctcgccg gaacgttcgc ccgctccctc catctggtcg gcgcctccgc ccggcatcca
     6361 ccagcctccc gacgacaccg aaggtgatct ctttgcccac atgcactccg tccgacgctg
     6421 ccctcgcccc ctcccacccg gccggcgcct cccaactcga cgtcgcgggc gagctgctga
     6481 ctctgctgcg cgaccgtacg accgaaccgc gccccgacac gcagctggaa gccctgacgc
     6541 tggccgtggc cgccgatctg cccgtcctgc tgtggggcga gccggggatc ggcaagaccg
     6601 cgtccctgac ccagctcgcc agggccctcg acctccccct gaccacggtg atcgccagtg
     6661 tgcacgaacc atccgacttc tccggactgc ccgtcgtcgg agcagacccg gcggaggagg
     6721 gcattccgat ggcgccgccg gactgggccg tgcggctggt acgggccggc cgcgggctgc
     6781 tgttcctgga cgagctgtcc accgcgccgc cggccgtcca ggccgccctg ctgcgcctcg
     6841 tactcgaacg gaggatcggc gccctgcggt tgccgcccgg ggtccggatc gtcgctgccg
     6901 cgaatccgcg ctcctcggcg gccgacgggt gggagctgag cgccccactg gccaaccggt
     6961 tcgtccacct ccactgggtc cacgaccccg agaccgtggt acgcggactc ggcggaacgt
     7021 ggccccgggc gacactgccg cggctcgacc cggagaagct gcccgaggcc gtcgacttcg
     7081 ctcgccgcgc ggtgtgcggg ctcctgtccg cccgccccgg cctggtgcac cggctgcccg
     7141 gcaacgagac ccgccggggc ggcgcctggc cctccccgcg cagttgggag acggccgtgc
     7201 gcatggtcgc cttcgccacc gccgccggct cctcgaggga ggtgctctcc ttgctggtca
     7261 ggggcgcggt gggggacggc ccggggctgg agctgatggc gagcctggac cggatggacc
     7321 tcccgaaccc ggagacgctg ctcgccgacc cgtccggagc gctcctgccc gagcggggag
     7381 atctgcgcca ggccgtgctc gacggcgtgg tgcaggccgt gcgcaaccgc cccgacaagt
     7441 cccgctggga cgcggcgtgg accctgctcg tccgggccgt ggagacgggc gccccggacc
     7501 tggtggtcgt ccccgcgaac acactggccg cactgcgccg cgacgactgg gacgtgccgg
     7561 aatccatcgg ccggctcgcc ggagcggtca ccctctccca gcgcgcggac cacgcggcgg
     7621 agcgagcagc ccaacgggct gccggtgtca ccgcgaggcc ggggcgatga ccgccgccgc
     7681 gccggaggcg ctggacctcg acaagctctt cgccgcccgg ctgcacgccg cacggagccg
     7741 gccgtacctg gccaccgcgt tgttcgccct gcacaccgtg gagtcccggc aggcaccgac
     7801 gatggccgtc gaccggcact ggcgctgcta cgcgtcaccg gcgttcgtgg accggacgcc
     7861 ggtggaggaa ctggccggag tgtgggtgca cgaggtttcc cacctgctgc gcgatcacca
     7921 cgggcgcagt gaccggtacg cacgggagca cggggcgacc ggtcccgcgg agcacctgcg
     7981 catgaacatc gcggccgact gcgagatcaa cgacgacgcc ttcggcgacg ggttggcccg
     8041 gccggaaggc gccgtcgggc caggggcgct ggggctgccc gacggggaac tcatggagga
     8101 ctacctgcgc cagttccggc tcgggccgcg tacgcagagc atggcctggc tggactgtgg
     8161 cagcggcgcc gacgggcagg aacgggaatg ggacctggga cccggcggtg cgcacggcct
     8221 ctccgaacag gaacgcgaag cggtcaggtt ccgcgtggcg cggggcatca ccgcgcgccc
     8281 cggcaggacc tccaagggct ggcggcgatg ggctcaggaa gtggtccatc cgccgcagcc
     8341 gtggcgggaa ttgctgggag cggcggtccg ctccgctgct cccggctccg gcgcgagcga
     8401 ggactacact tacggccgac cgtcgcgacg ctcggccggc gtgcccggcg tcgtcctccc
     8461 cagcctccgg cgcaggccgc cccgggtctc cgtggtcatc gacacctccg gttccgtcga
     8521 cgacaccgaa ctgggcagcg cgctgctcga agtggcggcg atctcccggg ccctcggcgg
     8581 acgtcgggac ctggtctccg tactgccgtg cgacgcagcg gcccgggtcg tgcatccgct
     8641 ctgccacgcc gagggcatac cgctgctcgg cggtggaggt accgacctgc gcacggggtt
     8701 cacccaggcc ctccgcgcgc ggccccgacc ggacgtcctg gtcatcctga ccgatgggca
     8761 gacaccctgg cccgacacac ggccgccctg ccggacggtg gtgggcctct tcccccgcgg
     8821 gtacggaaac cggtcctggg acgaggacga ccccgaccac gtgcccgaca cgccgccggc
     8881 gtgggcgcga gtggtggaca tcggatcggc tcccgcggtg gggtgagcga gtcggctcgt
     8941 gcggtgcggt gagtcagcgg cgaacggccc cggtcacgac cacacgtgcg agcgacgcgg
     9001 ccaggggccc gaaagcgccg tcgccccgga agccccggca ctccggaagc cccgggcccg
     9061 tcggatggat gacgggcccg ggaccttcgg tcaaccgtgg atcagacgcg gtcggcagcg
     9121 atcaggagat actggaaaga accgtccttg taagagttga tgaacgcctc ctcgatgccg
     9181 gtgacgaggg aggacgtggc tcgcagctcc cagtacggca aggtcgcgcc ggtcaggtcg
     9241 atgactgcct gcggcacgag acggttgtcg gccatggcgc gcagatactc gcggcgggaa
     9301 tggatgttgc actcgaagtg cgcgttgatc tgcgagaccc acttcgaggg ctggccgtaa
     9361 cgcgggttcc agcagccggt gatggtcaca taacggccgc cggccgcgag gatgcgggcg
     9421 tgctcggcga agaggtcgtg caggtcgacg tacatgctcg actcgttgtt ccacgaggcc
     9481 gcggcctgcc ccgaatcgaa gggcgtctcc agcatgttgc acacgcgggc ttgcacatgg
     9541 tcctcgatgc cgagttctat ggcgcgctgg ttggcgaagt cggcctgctt ggccgacagc
     9601 gtgacgccac ggacctcgca cccgaagcgc tgatgggcca ggaccatcga accgccccgg
     9661 ccgcagccgg cgtccacgag catgtcgtcg cgcccgacgc ggccgaggtg gtccaggagg
     9721 acctcggtct gcgccgactc cagacggtgc agctcggcga tcagccgctg ctcgtacccg
     9781 ctgtcgccgg cgtctccgag ggcggcgtgg tcgacgtcgc cgatgccgta atggtggtgg
     9841 tacagcccgt cgacctcgcc caggcgcagg ttcacgggcc tggcctcctg gtcccagtag
     9901 cgggcgatgt caccctggta gggcgacgcc ggggagggca cgaaggcgtg ggcgccctgt
     9961 gcggtggtga gctcggtgct ggtcacgaaa aggtccgtcc ttaccaaaaa tcgggcaggc
    10021 tgtaccggta ggtgttcgtc tggtgccagt agtggttgcc gtcgacccat gcggccacgc
    10081 cccgcaggaa gcgcagcacg ctcgggacgg gacaggcggc ggccagggcg gcggcctcgg
    10141 cttcgaaggt gtgcatgagg tcgttgtgga cctcgaccgc cttgagatag gcgtcctttt
    10201 cggagaggcc ctcccgctcg gcgatcacga cgggcagatt caggtgcgtg cccgggctct
    10261 tgagttcctt ggtgtacgag tagaggtcgt tgacgagggt ggtggcgttg ccggcgagcg
    10321 cgatgacccg ctgcacagcg ggcctggcgt gcaggtcggc cgggagctcg tagccgccga
    10381 cggtgtcggt gatcgtgggg cacgggcgga agttgttgaa ctggcgcatc gccaggtact
    10441 cccacacctc gggcacgtgt tccgcctgtg cccaggcggc ctccgcgagg taccccaggt
    10501 gcagacggga catgtcgtgc cggtacctgt cggcctggga gggggacgcc ttccgcacga
    10561 agtactccat cgcggagcgg taggcgcgcc ggggagcgtc cgactggagc gactccaccc
    10621 actccgcctc gtactccccc gtcgtgtgca gcgggtcgag agccgtgtgc gcgagcagga
    10681 ggcggctgcc gaggccgatg ggcgagccgc cgtggtcctc gcagtagcag tcgtcgaccg
    10741 cgttctccgc gaccatcagc cgcgtggcga ccatcaggtg ttcgatggtg ggagcgtccg
    10801 gatggcaggc gaccatgtag cggccgacgg agaagccgtc gaactcctcc tcccactccg
    10861 gcgggtaggc ctggacctcg tccaccgccc acctcttgat cctgcggctg acctccccca
    10921 cccgtgccgc gtcgggctca ggaacggggt ggtagtagag gccggggacc ggctcaccct
    10981 gtgccggcgg gtcggacgcc ccgaacaccg acgagccctc ggagaccccg cacgccgggg
    11041 agacttcccg cctgccggga cgcaggctcg acgtacccgg accgctgggg ccgcacagga
    11101 tccgctccag gaccgagctc gcctgcctgg cgtgcctcgc ggcggcagcg tcctcctccg
    11161 tgcaccggga gttcggctca cctccccgtg ccgtcgtctc accacccgtg ccgtcatcgc
    11221 gcccgggcgc gggcacgggc acgggtgcgg actcgggcac ggcccggtgc gcgggtgcgg
    11281 actcggtcac aggcgcggac ccgggtatct cctgggcggt ctcccgcacg gcggggaagg
    11341 gtgaggggaa ggaggggggc cctggcaggg tgagcagcgc gtcttccccg gattcggcct
    11401 cgtcagcagg tgcggctgcg gcccgggccg cagccgcagg cgtactcgac tgctgagggg
    11461 aagacccagg atcgggcatc cgtaactcct tcgcgacggt ggtgatcggc gtacgcggcg
    11521 gcaaccgagg aagaacggaa ggggtgaaca tcgggaaatc cgctcagctc ccgagaacca
    11581 gttaacgtcc ggcccaccca gctcgtccca cgacctcgat ggagttactc cgatgcagtg
    11641 atcccgcccc aagccgtgtt tatccggacg aaaaagtgga cggtgaggac gcgcacggca
    11701 gcacgttcga ccgacggcag ggcatggtcg agggcccgcg caatcgccca cggccggccc
    11761 cggctcctgt cacggtgccg gtggcggaac cggccagccg tcacacatcc gtcacccgtc
    11821 gcctgcggtc cgatgccggc cagacatagg gaagaccttc gggaacgtcc ggaaagtgcg
    11881 tgcgataaaa ggagggatct ttggtgacca gcgctgactg gtggctgcgg tggaaggcgg
    11941 agtcgcccag ccagttgggc aactcgtcgg ctgccgcgag ttccgcgtaa ccgcggggcg
    12001 ggtcagcgaa gtcctcgagc gcggcgaagt cccgcatcat ggttcccgca caagtgtccg
    12061 ccctgccgct gtcggtccag acgtggcaca tctcgaggcc ataccggacc agagcctcct
    12121 cgtagccggc ccacatccgt acggcggggt ggttccgcca gccgtagccc ggcacggtca
    12181 gaccgcgcag cacctggagc gtctccaccc gctgcttgcc cagcctgcgc atgtcgagca
    12241 cggccgcgct ggcggcgaac tccgggtgag ggagaaacgt ctgcatgctc gctgcccagc
    12301 ccttcacgct ggtaggcgcc cgtgtccgcg ctgtgcaggg ccccgacgga agcggcgggt
    12361 cgtcgacgtt cgtgtccgcg ggcctccgca ggagcaacaa tcacagtact gaccacccgt
    12421 cactaccacc gtcaccgaca cctggtggac cagcggtccc gttcgacgtc ctgtgcttcc
    12481 tgactcagct acctgacagg caccggacga cgtacgtcat gtgctggacg ttgccaaccc
    12541 agagccattc cgtcggcccg cccgtgcccc gcccggacgt cgcgggcccg tccgcgcaag
    12601 cgcgcagcca atgctctccg gccccaccgg tcgcttcccg gaactcgggc agaccgagaa
    12661 tctgccgggc cgccctccgg ttgaccgcga tccgctcggt tccgcgggtc aaaaccttgc
    12721 agagaaggaa cgcgttcccg gtggtgtagc ggagaaagcc ccaaggcggg cctccttttc
    12781 tgtccggctg cggcacctgg gcgagggcgc cgacgggctg caccccgtag tcgccgtacc
    12841 cgagcgacgg caagtaggta cgaccgctcg cccgtatctc gctccacatg tgccagtcgg
    12901 tgcgaggctc ttcgcgcaag ccctgttcca gcatgtcgcc cgtgacgcga gggaatcccc
    12961 cgcccagcac ggcggcggtc cgccacggtg ccagggcaaa cagcgcgtca agggcacgca
    13021 gggcctcctt gcccgccccg ggccggtctc cgaggacgct gctcatgtcc agcatcagat
    13081 cgacgggcac agtggaacag gcccgagcca ggagcatccg aacagcttca gcggtgccgc
    13141 cgtcccactc cgtcgcgacg cgtacgcgga cgccgacacc gcagccacag cggcgggcca
    13201 cctccacggc cgctgtctgc tgcgcctcgg tccgttccgg ccccgtgacg ggacgcagcc
    13261 ggcccaactc gctgtaggca gacagtgcgt cggcgagccc ggaaatctgc gcgtcctcgg
    13321 cgaagggagc gtcgatccag ccgtcatgat gacgatggac gccactcacc ggggcgacga
    13381 acttccgcac cgcggcctcc aaccgtgccg acccgacggc gggcaggggc ggaagattcc
    13441 acagcggcat gagagcggcc ctgacgtccg gtcgcagacg tcgataggcc gcgaccgcgt
    13501 gcggccgagc cggcaggaca ggaacataga gcggtccgga catcgcagct ccccctcggc
    13561 actgcccgcg cgctttccct ctctcccagg gtcagcgaac gtgaggcacg tgagaagaga
    13621 gccctttcag cctgaatggc cgacatgcgc gttgcgtgcc gatgccgcgg ctacccgagg
    13681 aacgacaacc ggacctggcg gctgggattg tccccgttcg tgtcgaccag gcagatcgac
    13741 tgccaggtgc ccagttccag ggagccgctg aggacgggga gggtggcgtg gggagggacg
    13801 agggcgggga ggacgtggtc gcggccgtgg ccggggctgc cgtgccggtg gcgccagcgg
    13861 tcgtcgggcg gcagcagatc ccgcagtgcg gcgagcaggt cgtcatcgct gccggcaccg
    13921 gtctccagga tggcgatgcc cgcggtggcg tgcgggacga acacgttgag cagaccgtcg
    13981 cggccgcgtg ccgcgtcggc gaggaaagtc tcgcagtcgc gggtgaggtc gtggacggtc
    14041 tcggacgagc cggtggagac tcgcaggacg tgggtgcgga gtgcgtcggt catgctccca
    14101 ttctggggcc gggtgccgtc cgggtcgcgg gaaggttccg gggccgcgtg tggttggcgc
    14161 aggcatggag actgtggagg ccgtggtcat cggtgccggg caggcggggc tgtccagcgc
    14221 ctaccacctg cggcgtacgg gcttcgtgcc cggtacggac ttcgtcgtcc tggatcactc
    14281 gcccgcgccc ggcggggcgt ggcagttccg gtggccgacg ctgacctacg gccgggtcca
    14341 cgggatgcac gcgctgcccg gcatggagct gaccggagcc gatcccggcc gcccctcggc
    14401 ggaggtgatc ggagagtact tccgcgcgta cgaacacgcc ttcggcctac gggtccggcg
    14461 ccccgttgac gtgcgggagg tgcgggagat cggtgaggcc ggccacggcg gccgactcct
    14521 ggtgcagacc tcggacggtg actggtcgac acggacggtg atcaacgcga cggggacctg
    14581 ggatcgcccg ttctggccgc gggtgcgggg gcaggagctc ttcctgggcc ggcaattgca
    14641 caccgcgcag tacccgggtc ccggcgcgga cgccttcgtg ggcaggaggg tggtggtcgt
    14701 cgggggcggc acctcggcgg tacagcatct gatggagatc gccgaggtcg cgagggagac
    14761 cgtgtgggtg acccggcggc cgccgctctt ccggacgggc gagttcgggc cgcaggaggg
    14821 ccgtgcggcc gtggcgctgg tggaggaacg ggtgcgccag gggttgcctc cgcagagcgt
    14881 ggtgtcggtg acaggactgc ccatgacgga ggagctgcgg cgtgctcggg agcgcgggat
    14941 tctggagcgg cgtccgatgt tctcctccgt gaccgccgac ggtgtccagt gggacgacgg
    15001 gagccgggca gccgcggaca cgatcctgtg ggcgaccggg ttccgccccg ccgtcgatca
    15061 tctggccccg ctgcggctgc gcgagtcggg cggcggcatc cggctggatg gcacgcgagc
    15121 ggtccgcgac ccacgcgttc acctggtcgg ttacgggccg tcggccagca ccatcggcgc
    15181 caaccgtgcc gggagggccg ccgtgcggga ggtacgggac ctgctgacgg ccactgccgg
    15241 cccctcggac accgacgcat cagcgagtca ggcgactcac gtgactccgg cggctcagac
    15301 ggctccggcg gccgcctgaa ctcacggccc accgacgcgg acgaatggtg ccgtgactcc
    15361 tctggagtcc ctggcgactc acgcagggtg gacagctggg acgagcgccc cgtccgtggt
    15421 ccggatctgg tgcctggcgg cgtactactg cgacagtagg gcccgacggt gatcacccgt
    15481 acggtcttcc gcagggcggc ggccggaggg tcgccggcgc ggacaggcat ggagccggcg
    15541 gacaggcgtg gagcctgtgc gggtcggcgc gaaggctgac aggtgagacg gaagggaggc
    15601 gtcgtgcgcg tagcgctctt cgtcacctgc atcaacgacg cgctctatcc gcgcacggga
    15661 caggccgtgg tggcgctgct ggagcggctc ggtgtggagg tggacttccc cgacgcgcag
    15721 tcgtgctgtg ggcagccgca gttcaacacc ggctaccggc acgcgaccga gccgttggtg
    15781 gaacgctatg ccgacgcctt cgaggggtac gaccacatcg tcgtcccgtc cgggtcgtgc
    15841 gcggcgatgg tgcgggacaa ctacccgcgc atcggcgcga aggccgctgc cgaggggcgg
    15901 ggccgggtgc tgtccgcggc ggcggagcgg gtggtgcccc gcacctacga gctcacggag
    15961 ttcctggtgg acgtgctggg cgtcacggac gtgggggcgt actacccgca caccgtcacc
    16021 taccacccga cctgccatgg gctgcgcatg ctggggctcg gcgagcgtcc caggcgactg
    16081 ctggaacagg tggagggact ccagctgagg gagctggagg gcgcggagga gtgctgtggt
    16141 ttcggaggga cgttcgccgt gaagaacgcg gccgtctcct ccgcgatggg cgcggacaag
    16201 gcgcgccaca tcgaggcgag cggcgcaggg tcggtctgca cggtggacaa ctcgtgtctg
    16261 atgcacatcg gcggcgtcct ctcccgctca gggtcgcggg tgcgccccgt gcacctggcg
    16321 gaaatcctgg cgagcacgcg tgaggcgccg ctgtgagacc tcagcggcgg acaggtgagg
    16381 cggccccagt ggcggacgag gtacgccccc tggtgaacga ggcggccccc gagccgggct
    16441 ggagttccgg cacgacgggc gaaagggttc gggtgcggac gggcggcacg gacgccgggc
    16501 acgccaggca cgccgagagc gccgtgcgcg tcgacaaggc gagccgggcg agcgagtcgg
    16561 gcgtgacgag cgagtcgagc agggaggcac ggtgagcgtc acctacctgg gcatgccgcc
    16621 cttcccacag gcggcacagg actccacccg ggacacacgg ctgcgcggca acctgcggca
    16681 cgccacccac acgatccgcg acaagcgggc gggcgcggtg gcggagctga cggactgggc
    16741 ggcgcttcgc acggccggtg cgcagatcaa ggaccgcacg ctgcgccatc tggacactta
    16801 tctggaacag ctggaggccg ccgtcaccgc ggcgggcggc accgtgcact gggcggtgga
    16861 cgcggcggag gccaacgaga tcgtcacccg gctcgtacgg gagaccggcg agcgcgaggt
    16921 cgtcaaggtc aagtcgatgg cgacccagga gatcggcctc aacgaggcgc tggaggacgc
    16981 cgggatcgcg gcctacgaga ccgacctggc ggagttgatc gtgcagctcg gggacgaccg
    17041 gccctcgcac atcctggtcc ccgccatcca ccgcaaccgc ggcgagatcc gcgacatctt
    17101 cgccgagagg atgggccggt gggggcggcc cgcgccggac gggctcggtg acagccccgc
    17161 tcagttggcg gaggccgcac ggctgcacct gcgggagaag ttcctgaacg cgaaggtggg
    17221 catctccggg gcgaacttca tggtggcgga gagcgggacg ctcgtcgtcg tcgagtccga
    17281 gggcaacggc cggatgtgtc tgacgcttcc cgagacgctg atctcggtgg tcggcatcga
    17341 gaaggtcgtc cccacgtggc aggacctgga ggtcttcctc caactgctgc cgcgttcctc
    17401 gacggccgag cggatgaacc cctacacctc gacctggacg ggcagtgccg acggcgacgg
    17461 cccccgcagt ttccatctgg tgctgctgga caacggccgt acggacacac tggccgacca
    17521 ggtgggccgg cagacgctgc ggtgcatccg ctgctcggca tgtctcaacg tctgccccgt
    17581 ctacgaacgt gcgggcgggc acgcctacgg gtcgccctat ccgggcccca tcggagcgat
    17641 cctcaccccg cagctcgaca gcgtggagac cggcctggac gcgtccttgc cgtacgcctc
    17701 gtcgctctgc ggtgcctgct acgaggtgtg ccccgtggcc atcgacatcc ccgaggtgct
    17761 ggtgcacctg agggagcgcg tcgtgcaggg cgggacggtc acggtccgcg ggcagcgtac
    17821 gactgtgcgg cccgccaagg ggcacgcggc cgaacgagcc gccatgcggg cggcctcctg
    17881 gaccttcgat catccgcgcg ccctgcgcgc gggcgagcgc ctcgcctcgc gggcccgccg
    17941 gctggtgccg aacaggctgc cggggccggg cagcgcctgg acggacacca gggacacgcc
    18001 ccgggtaccg cccgagtcct tccgtgactg gtggcggcgc acgcgcacac ccgcgggggc
    18061 cgcggggaag agcggagggg agagcgtccg tcaggaggga cggccggaaa cgcccggcgg
    18121 gagggaccga caggaggggt ccgatgagca gccgtgagac cgtgctgggc cgggtgcggc
    18181 gcgccctggc cgacgtgccc cgcggggagc ggcccgacga ggcgccggtc ggccgcgact
    18241 atctgcgggt gcacggggag cgcagcccgg gggagaccgt tcggctgctg agggagcacc
    18301 tgaccgacta ccgggcccgg gtgcaccact gctcccccgc ctcgctgccg gagacggtcg
    18361 ccgagctgct ggcacggcag gggtcgcgca gtgtggtgac tccggccggg gttccgggcg
    18421 cctggctgcc gcaggatctc gagcacgtcg cggactcgcc ggcgttgact ccgcacgatc
    18481 tggacgcggt cggcagtgtg gtgaccggct gcgcggtcgc cgtggcggag acgggcacgc
    18541 tggtgctgga cgcctcacgg gaccaggggc ggcggagcat cacgctcgtg cccgaccatc
    18601 acgtctgcgt ggtgcgggtg cccgatcagg tcgtcggctc ggttccgcag gcgctggagc
    18661 ggctggatcc cgcccgcccg cagacgtgga tctccggccc ctcggccacc agcgacatcg
    18721 agctgaacag ggtggagggc gtacacgggc cgcgcaccct cgacgtcgtg ctcgtgggcg
    18781 aggagtcctc gatgttctga ccgccgatca cccaactctc cgggctcacg gagacgtcag
    18841 gggaggatgt tcttcaagtt acttaccgga accggtggtt cggggcgcgt gtgcgtgcaa
    18901 aagttcgacg cgatcatctt cccccagcgc ttcccacaag gagacacgcg cacgtgagcc
    18961 actcccccat ctccgccccc cacaccgtgg cccccgccgg gcccgcggaa cccggcttca
    19021 gacccgacgc accggtcaac agaccactgc tgatggtcgt catgctctcc gccgcagcgc
    19081 tgtcggccct ctccgccata ctgagcgcgt cgatggtgta cctgggaggc aaggacctcg
    19141 ccgaccagaa cgtgcgcaac gcggtcgaca gcgacccttc cgccgtaggt ctcccggcgg
    19201 acacccggtc cgccgatctg aagcggatgt ccccgacggc ctgggacgac gtcgtcaccc
    19261 actggcagga caccatgtcc gcacgtgcgg cgttcgcggt cgccctggcc ctgctggtgc
    19321 tgctctgtgc gctgctggcc cgcaacgcct ccctgtggtc ccgtgcggcc ctcagcgtcg
    19381 cggtgctgct gggaggcgcc ttcccgcatg ttctggtgct gcgggacgcc ccgccgacag
    19441 ggctctacgc gaccagcctc gcagcccccg cgctggccgt ggtcaccgtg gtgctgtgct
    19501 ggctgccgcc agtgggacgg tacgccaagg cccgcagccg atcctgaact ctccctcagc
    19561 tactgcttcc ggcaccggcc cgcccggtgc cgcggacgaa gggcgacctg gtcgccgggg
    19621 cggtggaggt ctgcttccca ggcggcgctc cgccgacgcg tgccagcgca ccgacgcctg
    19681 ccgacggtga gacagtcgag caggctgctg caccgtacag ctagtctggt cgcccgcacg
    19741 gcagccggaa gcgagccctc cgggtgccgc gaccgcccga gctcaccgga ggcccgccat
    19801 gaaccagccc gcgccccgcc aggtcgcctc gatcgagggg gtcggtgtcc gccgcatgac
    19861 ctcggaccag gtcatcctcg acgggatcga ctggtcggtg cgagccggtg agcactgggc
    19921 actcctggga gccaacgggg cgggcaagac gacgttgctc aagctgatcg gcgccgtcat
    19981 gcaccccacg tccggcaccg tcgaggtgct gggcaaccgc ctcggccgag tggacgtgcg
    20041 agagctgcgc gcccacatcg ggcacgtctc cacctcccag cgcgtccccc aggacgcgcc
    20101 ggcgcacacc gtcgtgctga ccggcgcgac gggcaccgtg cagccgctgt ggcgcaagta
    20161 cgacgacgag acccgccagc tggcccacga cctgctgtcc gagctggagt gcaaggagct
    20221 cgcggaccgg cccttcgggg tgtgctccgg cgggcagcgg gcccgcatcc tgatcgccag
    20281 ggcgctgatg cccgcgccgt ccctgctgct gctggacgaa ccgttcaacg ccctggacct
    20341 gccctcccgc gaggacctga tcgacgcgct gcgccggctg gccgcggacc gtccggctct
    20401 ggcgacggtc acggtcaccc accacctgga ggagctgccg ccgaccacca gtcacgcact
    20461 gctgctgcgc gagggccggg tcggcgcgtg cggccccgtc ggcgacgtgc tgacgggaga
    20521 gctgatgacc cggtgcttcg gccgccccat cgacgtcact caccaggacg gccggtggct
    20581 ggcccgctcg ggacaccgca gctgagaggg ccgctccggg gggcggccgg gcccggctcg
    20641 gacagccgcg gcgggcgggt ccaggccggt cccgggcccc gagtccgtcc cggagcccgc
    20701 atcggtactg gatcccggag ccggtcctag gacccgaggc agaccgcgtt cggtcccgcg
    20761 cccgttccgg cacggtgcgg cccgcccgta gcgtcccggt atggactcct cgacgacacg
    20821 cctcggacac ggcgacccca caggaacgct ggacgaagcc ctcgaacgcc tccactccac
    20881 cggtcccgag ttcgagggct ggctgagcaa tcacgctccc atggcggtcg aggcgctggt
    20941 gcggcacgga gagacacgca cggcgcaccg ctggctcgac ggttacgcgg agaagctgga
    21001 ggacccgccg gggagtcgcg cgcccgtcac ggacaccaac tggcgtgcgg cgctgggcga
    21061 cccctcccgc ctgacggact ggacgcgctt tttcacccac aaggtggaag agcggccctg
    21121 gcgcgacgtc ctcgctctct ggtggccgct gctgctgccc ggcatcgccg gaggcgcgac
    21181 ccaccccgtg atccggacgg gccacgccgt gcgcgccctg ctcaccgagg acggcgagac
    21241 cgcaccgcgc cgtacggagc tcgcccacgc gctcggttac tgggccgcac ggcacagcac
    21301 gctggcagag atcgaaccgc tcccccgagc ggggtcagcg gacgagagct acgaggccgt
    21361 accgctgatc tcccagcaga gcggcggcat ccgcgaacgg ctcgcccgga tcgccgcact
    21421 cccccagcga ccgcgcacga cggaggccga aaaccagccg gagcgagaag gagggagca
//
