LOCUS       NZ_QOIM01000024        24769 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces reniochalinae strain LHW50302
            NODE_11_length_274796_cov_17.7578_ID_21, whole genome shotgun
            sequence.
ACCESSION   NZ_QOIM01000024
VERSION     NZ_QOIM01000024.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces reniochalinae
  ORGANISM  Streptomyces reniochalinae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 274796)
  AUTHORS   Li,L.
  TITLE     Streptomyces reniochalinae sp. nov. and Streptomyces diacarnus sp.
            nov. from marine sponges
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 274796)
  AUTHORS   Li,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUN-2018) Department of Pharmacy, Ren Ji Hospital
            School of Medicine, Shanghai Jiao Tong University, Pujian, Pudong,
            Shanghai 200127, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-FEB-2016
            Assembly Method                   :: A5-misseq v. MARCH-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003323735.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 01:54:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,751
            CDSs (total)                      :: 6,669
            Genes (coding)                    :: 6,475
            CDSs (with protein)               :: 6,475
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 4, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 66 of 194
            Pseudo Genes (incomplete)         :: 154 of 194
            Pseudo Genes (internal stop)      :: 16 of 194
            Pseudo Genes (multiple problems)  :: 41 of 194
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:03:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 213336
            Orig. end                         :: 238105
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QOIM01000024.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24769
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24769
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24769
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14769](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14769)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    455..471
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.78"
                     /tool="antismash"
     misc_feature    complement(953..968)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.92"
                     /tool="antismash"
     gene            complement(2245..4836)
                     /locus_tag="DQ392_RS06390"
                     /old_locus_tag="DQ392_06380"
     CDS             complement(2245..4836)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019357940.1"
                     /locus_tag="DQ392_RS06390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06380"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_245981215.1"
                     /transl_table=11
                     /translation="MSTEPAGGARRATPLLDTLRIGIVMLDGRGDVLVWSPAVQEILGW
                     PAEETIGRPIEELIVSGEEERRARVEALRRTHTWRGNLSMRHRDGSVVEVEGRGSLLRD
                     TEHHPFVLVNIVETSRLRTVEHELAALDALFASSPLGIALFDTERRLVRYNDALLRLVD
                     AADTDLVGRTVEALLPAAMAEEVMQIQTGVLETGRSVVDVVTPSLDGGGARSVSYARLS
                     DRGGEVFGVSCTVMDVTERLEALDKAEAARGRLALLDHLGVALGDRLDVRAISEAVTGA
                     LVPRFADYAGVLLRGEVAAGGDLPEPVIPVGTPLHMLGFAARHAGERVERLLRLGSEIV
                     YARDSLLGRALDSGEPQLATSPEEILRASRAGDPTTDATLDLDVHSLMAVPLRARGTGL
                     GLLVVSRAENRDPFVDDDRALAVELADRSATFLDNARLYAREREGALMLQRSLLPQHIP
                     EPPGVVLAYRYVPGSSGTEVGGDWFDVIPLPGGRVAFVVGDVMGHGLHSAVTMGRLRTA
                     VRTLAGLDLPPDELLARVSTVGDDLSHGPDEPMMATCLYAVYEPAPTSAGKRCGVLTLA
                     SAGHVPPLLVTPEPDGGCRARPVDVPSGTPLGIGPALDGSWDLTEVEIEKGSVLVLYTD
                     GLVESRGADITAGIDRVCGLLAGPSRCRVEPEPGFSWDGSGGYVSPGPVEDTGCGGIEN
                     ACDILISALREQGGPGDGRLSTRDDVALLMARLGGLPGDTAASWSFTTGDYAVRRAREA
                     VRRTLHEWGLAELEDTGVLLVSELVTNALRYARGPIGVRMVRDTGQPAGAQGRVLVVEV
                     SDPMPEPPRERVVTEEQEGGRGIQLVAGQARRWGTRHGPEGKTVWFELPLD"
     gene            complement(4951..5154)
                     /locus_tag="DQ392_RS06395"
                     /old_locus_tag="DQ392_06385"
     CDS             complement(4951..5154)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019357939.1"
                     /locus_tag="DQ392_RS06395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06385"
                     /product="DUF2188 domain-containing protein"
                     /protein_id="WP_181856298.1"
                     /transl_table=11
                     /translation="MQSVSGDSEAVRPWRLIRQDCHGNRYRVGSYATRAEALHLAERLG
                     ERGDGYLVEHQRSDGSVQAVSG"
     misc_feature    complement(5208..5219)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.1"
                     /tool="antismash"
     gene            complement(5348..6100)
                     /locus_tag="DQ392_RS06400"
                     /old_locus_tag="DQ392_06390"
     CDS             complement(5348..6100)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998196.1"
                     /locus_tag="DQ392_RS06400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06390"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_114014488.1"
                     /transl_table=11
                     /translation="MPFGEQPAYLRVASDLRKKISDGSLPPHARLPSQARIREEYGVSD
                     TVALEARKVLMAEGLVEGRSGSGTYVRELPSARRVARTGYRTMEECTPFRQEQSDERVR
                     GTWESRSEREEASHETAERLFIEPGDKVMRTRYVFQVEGEPVMLSTSWEPLALTGRTPV
                     MLPEEGPLGGRGVVERMAAIDLVVDNVTEEVGSRPGRAEEMAALGGVPGHAVLVVARTY
                     FAGKRAVETADVVVPADRFKLAYHLPVR"
     misc_feature    complement(6244..6259)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            complement(6358..7050)
                     /locus_tag="DQ392_RS06405"
                     /old_locus_tag="DQ392_06395"
     CDS             complement(6358..7050)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019549721.1"
                     /locus_tag="DQ392_RS06405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06395"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_114014489.1"
                     /transl_table=11
                     /translation="MSSRPRGGARPGPEAAQVPPAAAPAADPASHAPAGAAVADLRVLA
                     HPLRLRLLSLLTGQSYSAAEAARVLGQSQANVSYHLRRLHTAGLVEAAGEVEVRGGTAK
                     RYRHDPDSGDRLGAAGGVGTYLALSGTLGEELRRRTAQRDTSVPGEMTDAEVWLPGQVW
                     EDVRERARALGGVLHDQALPPGTEGAVRVSATMVLFAMEPAGEAETGGETKTAGEGASG
                     AGGHGAES"
     gene            complement(7065..8387)
                     /locus_tag="DQ392_RS06410"
                     /old_locus_tag="DQ392_06400"
     CDS             complement(7065..8387)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019357936.1"
                     /locus_tag="DQ392_RS06410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06400"
                     /product="MFS transporter"
                     /protein_id="WP_245981216.1"
                     /transl_table=11
                     /translation="MTPPASSRPRGRGADSAQRLPLRALMRRRGFRGLASGRALTYFGN
                     AMAPVVLAFAVLDMGGSAVDVGLVVGARSVSNVVLLLFGGLLADRLPRALVLQGAALAA
                     ALVQSGVGLALLAGRAPMGALLVLSVVQGAVAAVSVPASAALIPLTVPADELRPANALS
                     RMGVNAGMIAGTSLGGLLAAVASPGWGMVLDGAAFAGASLAFRLAGRERASVREQTGTV
                     AAPARPWRELREGWKEFVSRTWVWVVVLQFFVVNAVAAGGIQVLGPTVADATFGRTAWG
                     FVLATQMAGALAGGVLVARSRARHALRLGVAVVVLDALPLVALAQSADVAVLVVAMFIN
                     GIAIEQFGVAWDLSLQENVPQERLARVYSYDALGSTLALPVGEMAAGPFAERFGVRPTL
                     LCGVALVTLATVGALCSRQVRGLTTGQSRPAAGPPVVETRA"
     misc_feature    8421..8434
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.4"
                     /tool="antismash"
     gene            8532..8993
                     /locus_tag="DQ392_RS06415"
                     /old_locus_tag="DQ392_06405"
     CDS             8532..8993
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006350217.1"
                     /locus_tag="DQ392_RS06415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06405"
                     /product="VOC family protein"
                     /protein_id="WP_114014560.1"
                     /transl_table=11
                     /translation="MSTPTPTRHSWPDHLAAGAVRFARPTARFDAVRAFYVDDLGLPVL
                     AEWRDHSGYDGLVLGLPGTPVHMELTQHGAPPRIPEPHPENQLVLYLEDRAAHDRAAAH
                     LASRGHRPVTATNPYWPTHGATVFADPDGWQLVLAPWVFGRDPVPDARR"
     gene            9182..9937
                     /locus_tag="DQ392_RS06420"
                     /old_locus_tag="DQ392_06410"
     CDS             9182..9937
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058488.1"
                     /locus_tag="DQ392_RS06420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06410"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_114014490.1"
                     /transl_table=11
                     /translation="MTTVSGSTVDIPTRDGTADAYLVHPRGEAPHPAVLLYMDAFGIRP
                     ALRAFADRLAAAGYTVLVPNVFYRTGRAPVVELPDFIDPAQRPDLFRDLGPAFQTLTPQ
                     NATRDADAYLRYLAGLAQAAEGPVGVTGYCMGAALALRTAGAHPGRVAAAAGFHAANLA
                     TDAPDSPHLSADRITAELYFGHADQDPGMPPEQIELLERTLTSAGVRHRAEVYEGAPHG
                     FTQSDTAAHDPAAEERHWEALLDLFRRTL"
     gene            complement(10001..13300)
                     /locus_tag="DQ392_RS06425"
                     /old_locus_tag="DQ392_06415"
     CDS             complement(10001..13300)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="DQ392_RS06425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06415"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_114014491.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.4e-134,
                     bitscore: 443.5, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.1e-11,
                     bitscore: 38.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.2e-32, bitscore:
                     106.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEAADTYETCGFFMLRAPALPARPLLDVFGSLPADAETLRTGAW
                     QDNYAEQLLKLWWAPGVRDAVRAASPDLADAVERFDTLTGKSRRKAVRGLGRYLNRMSF
                     RSTPFGLFAGVTTGVFGAEQRTRLGHGALGRARARADSGWVMHLVKRLAFGAERSRDDL
                     RVRRNDLLHVSRGRVWLSTAEGYGLNEDAGAARTAAHGDEQRPTPRGRRSVSVRLTAPI
                     RSVLDLARTPTTLGELTAALTETYPRAGAERVAALLDGLFDSDILITVERPRLLVPHAA
                     GNDSLLRSVLLPVTEPAVARAIDGVEAAVNAFNRGEIPARGLLGAASAPMPEAVGGHMG
                     PTLQIDAALNRDGSLVLPRAVADLAEEAARVLLRVGAEDRYPPHLKEYADAFAERYGHR
                     SEIPLLEALTPETGLGPPRRYRSPGQAYPLPGVVPEPVDLSDRPAGPTRKAVLDRLVAG
                     ALARRERAVQLDDRLLEELAEVSAPKDDHRPPMPLIDLHLTLVAPGPGREHWRAVCGTA
                     GVVPGGRTFSRFHDLLDDGAQASLRQLAAAEETRQGDAVCAELSSLPQDARSINVSIRP
                     TAHTWELPVNVTPGRDEDRVIRLDDVLVGVAEGKLYLRSRMLGRRLHVTDRTMLNWAGA
                     PDPCRFLLEVSQSLSRTVSWFSWDALSWTMPFLPRVERGDVVLRRARWRLRAEEFPPST
                     GGDGDGDGLAAFADAFGAWAQTWMVPRLVNIASSDNTLLLDLTSAPCLRELRDSLERAP
                     EDGLVLEEVLPAPGEGFLRDADGEPYASEVVVPLVRTGQDPGRVARHIRPRKAADTAEE
                     PGARVKRVGSDWLAVKLYAEPDAHDTLLGVGLAGLTRRLSERYGVAAPFFLRYGDPAPH
                     LRVRFFVPDQDTRADVLGEVTAWAYDLAGGGHITDHTYVTYRREVERYGGPQLIADAEE
                     FFRQDSAAVVQLLADLRASPTGLPGLPHLGLDASRERAALVALTLDGLCALLVPEPEAR
                     HALARLAASRNAGGGLYRRAGRGLWAARTEDGPARALLDRAAAAWRPAAERLTRRMTEL
                     ERDGALQADRGDIVLAALHMHCNRMGLRPAEEADSYGVWRRLLDRAAHAPR"
     aSDomain        complement(12494..12688)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DQ392_RS06425_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.40E-12"
                     /identifier="RREFam001.1"
                     /label="DQ392_RS06425"
                     /locus_tag="DQ392_RS06425"
                     /protein_end="269"
                     /protein_start="204"
                     /score="38.4"
                     /tool="antismash"
                     /translation="RPTPRGRRSVSVRLTAPIRSVLDLARTPTTLGELTAALTETYPRA
                     GAERVAALLDGLFDSDILIT"
     gene            complement(13297..14769)
                     /locus_tag="DQ392_RS06430"
                     /old_locus_tag="DQ392_06420"
     CDS             complement(13297..14769)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="DQ392_RS06430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06420"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_181856299.1"
                     /sec_met_domain="LANC_like (E-value: 8.6e-20, bitscore:
                     64.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDEVLRLAREVADRLLESAGDAAGKADLADGAPGIALALRYAA
                     EVFDDSRYFTAGRIHLRRTAEASATAPLQAPGLYLGTAGVVWAVTEYARMEPRYLPTLA
                     TMTDRLARQTLAITLHTAAGSVASHDYDVIGGAAGWLAALLKAADVLGGRATDAVGQAT
                     DRLVDYLVELTRDDGGPLRWFCAPSHFPSIPGPDGEPTPLPGYVKNFPDGVYNLGFAHG
                     PPGILAALSRPDIAEAPGSTADPVAGSAAGTTDSESGSADPAAARPHRVRQGVRALART
                     LDALRIDGLDYPAWANLLLPHPDSRRPDTGAAQVPARSAWCYGPPGVAASLLSASSACG
                     DPEPTDLAVATLLGLERTPAEQQRVNSPTLCHGLAGLVTVYGRAAAQTGVPELFHMHER
                     FLSRMCSFADEDHPYLFPDYDPWGKQEHSAGLLNGAAGVLLALLGAVSEAAAGWDELLF
                     LTPRLPRADAPRADAPGGAGAETRQDRGMGET"
     gene            complement(15011..15163)
                     /locus_tag="DQ392_RS34305"
     CDS             complement(15011..15163)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQ392_RS34305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_181856300.1"
                     /transl_table=11
                     /translation="MSEDLLEDEFSLDLRVGHAEVSTSSAAATNNGGCATSRTSLCTDT
                     LSGCC"
     CDS_motif       complement(15077..15163)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSEDLLEDEFSLDLRVGHAEVSTSSAAAT"
                     /locus_tag="DQ392_RS34305_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15011..15076)
                     /prepeptide="core"
                     /locus_tag="DQ392_RS34305_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-2.70"
                     /molecular_weight="1938.1"
                     /monoisotopic_mass="1936.8"
                     /core_sequence="NNGGCATSRTSLCTDTLSGCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSEDLLEDEFSLDLRVGHAEVSTSSAAAT"
                     /leader_location="[15076:15163](-)"
                     /alternative_weights="1956.1"
                     /alternative_weights="1974.2"
                     /alternative_weights="1992.2"
     gene            complement(15332..17287)
                     /locus_tag="DQ392_RS06435"
                     /old_locus_tag="DQ392_06425"
     CDS             complement(15332..17287)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036873.1"
                     /locus_tag="DQ392_RS06435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06425"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_114014561.1"
                     /transl_table=11
                     /translation="MRWDDAFVEHEGAVARLRFAHMAAALPRMVGVVLRAGWETDPRAL
                     AGVVVAQAGQGLTTAFGLVAVNGVLSSLFANGPTDDKLRESLPALALLALVSVGMALLT
                     AWSTAMSGRLEPQVERAVSLRYYRSVTEVEIAATERPEVQRHLDAGKFGTDSARRMLSL
                     SVGVANVVIGMVAAAVVLASLHWALLPMLLAIALPKAWGAVRSARREYVSRRHWVDHRR
                     AVATLLQYLTMPHAAGEIRAHAAGSLLLRGYEEMSGLMETEQRRLARAQAATDLAAAAF
                     SGLASVGCYGVLWWLLTSGGLPMAVGGTAVVAIRTSTARLTSLVQQVNRMYEEMLRLSD
                     TEEAIQIASGHAIPRTGRPLPAPVREIQVRDVSFTYPGATVPALHRVDVSVRRGEVTAL
                     VGANGSGKSTLARILGGLLLSDSGEVWWVGGKAGGDGEDGGEGERVEVREAARADVFRS
                     VGMLTQDFPNWQMTAAANIAIGAGDRPRDAARLKEAARAAGVDELIEGLPHGWDSIVFK
                     GYERGVQLSGGQWQKLGTARSLYRGAPFLLVDEPTSALDPHAEIEAFDRLRTLADSGVA
                     VVLVTHRLAATASADHIYVLDRGHIAEGGTHGELMGRPGGLYRGMFDAQAAQYGLTASS
                     AEGVPAPRDDTAAQPR"
     gene            complement(17680..17994)
                     /locus_tag="DQ392_RS06440"
                     /old_locus_tag="DQ392_06430"
     CDS             complement(17680..17994)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQ392_RS06440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DQ392_06430"
                     /product="hypothetical protein"
                     /protein_id="WP_114014493.1"
                     /transl_table=11
                     /translation="MSTDDDDMPLAAPRVDVTADGRLSVPAHDVTALLRSIARSWAHST
                     RHGTPVRAGESHDSVRLEPTTVHALAGTLEQIADELDVQFIGVAGRTPPPASPSADTED
                     "
     gene            complement(18395..19060)
                     /locus_tag="DQ392_RS06445"
                     /old_locus_tag="DQ392_06435"
     CDS             complement(18395..19060)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019356529.1"
                     /locus_tag="DQ392_RS06445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06435"
                     /product="1,4-alpha-glucan branching protein"
                     /protein_id="WP_114014494.1"
                     /transl_table=11
                     /translation="MSIIYRTTLRPTKLELLEAWLPSQPWYVSGADRAALVNVGGFRLD
                     DPAGEVGVEFMAVIDEAGGEPVTYQVPMAYRSAPLAGADDGLIGTLDHGVLGKRWVYDA
                     THDPVAIAQTYALVTGRVDPQAQNESDTVDRTVAVREAAEPLVEDAGIRQVRHGSRSSD
                     VDLALPVDGLRRLRFLRVPRPDGVPETEGSLGHVTVSWTDLDGGPQRGVWCALVDSGE"
     gene            complement(19276..19494)
                     /locus_tag="DQ392_RS06450"
                     /old_locus_tag="DQ392_06440"
     CDS             complement(19276..19494)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQ392_RS06450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DQ392_06440"
                     /product="hypothetical protein"
                     /protein_id="WP_114014495.1"
                     /transl_table=11
                     /translation="MAYTALMDEDSARWLAGLDEPEGITHLGNGKVRFSKSAYAYLRNV
                     PSHMDGHIDSHDRVCLSEGSYQLTRSR"
     gene            complement(19739..20890)
                     /locus_tag="DQ392_RS06455"
                     /old_locus_tag="DQ392_06445"
     CDS             complement(19739..20890)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /locus_tag="DQ392_RS06455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06445"
                     /product="acyltransferase"
                     /protein_id="WP_181856301.1"
                     /transl_table=11
                     /translation="MKRKDYIDWLRNLAILFLFPFHTARIFNDNPEFYVKGPVNTLSSA
                     LVNISSFWFMPLLFLLAGMSSYYALRKRSARSYAKERYLRLFIPFLFGCLVIVPPQAYY
                     AMRFHNGYGGSYADFLGPYFTDFSHWTVLTGISPAHLWFILFLFLISIAALPLMLTVVR
                     NRYTPTWLDKPVLALAPAAGLALLSFLPEIGGENIFVYAGYVLLGFLIATDDSIIEALE
                     GNRRVFLCVAVPGAIGILIERFTIGSQANPLSAAWHYPVCWATLLAVLGYGKRYLDRRS
                     AFMDYFSRAAFPVYILHQTYLIVIAYYVLQTDVHGAVAFPAIMVPGCCLSIATYEIVRR
                     TPGLRIMFGLRAPRRPSRPLSTGPREQHGAHPPRPGTTTRPRP"
     gene            complement(20887..21528)
                     /locus_tag="DQ392_RS06460"
                     /old_locus_tag="DQ392_06450"
     CDS             complement(20887..21528)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025343.4"
                     /locus_tag="DQ392_RS06460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06450"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_114014497.1"
                     /transl_table=11
                     /translation="MPDTEGHSHPPGPVPRLPRDEVRRRLLAAAERVFAERGYADSKLE
                     DIARVAGFTKGAVYSNFGSKQELFGAILSERSEAELADVMAGLDAGADVPALIEQAARA
                     VAQRIIDDTERGRLGLEIAARAIRDEGTGAVVAPMRRAQRASAGRAVRAVTERAGITPP
                     VDPELAGTILHCLTNGLATEHLVDREGVDADTAERALRAVLGWLTEGARK"
     misc_feature    complement(21830..21843)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     18.25"
                     /tool="antismash"
     gene            complement(21953..22102)
                     /locus_tag="DQ392_RS34310"
                     /old_locus_tag="DQ392_06455"
     CDS             complement(21953..22102)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQ392_RS34310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DQ392_06455"
                     /product="hypothetical protein"
                     /protein_id="WP_181856302.1"
                     /transl_table=11
                     /translation="MQVREGPTLRGRALRRRLIVIGDLDAWSRHRYFKDLAQHELIHGW
                     TPER"
     gene            complement(22141..23229)
                     /gene="ychF"
                     /locus_tag="DQ392_RS06470"
                     /old_locus_tag="DQ392_06460"
     CDS             complement(22141..23229)
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="ychF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058470.1"
                     /locus_tag="DQ392_RS06470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06460"
                     /product="redox-regulated ATPase YchF"
                     /protein_id="WP_114014499.1"
                     /transl_table=11
                     /translation="MSLTIGIVGLPNVGKSTLFNALTKNEVLAANYPFATIEPNVGVVG
                     VPDPRLGKLAELFQSQKVLPATVDFVDIAGIVRGASEGEGLGNKFLANIRESDAICQVI
                     RAFKDENVVHVDGKISPKNDIETINTELILADLQTIEKVLPRLEKEARVKKDKQPQVKA
                     VQEAKDILEEGRTLFSAGIAQGTDRAEPLHELHLLTTKPFIYVFNVDEDELTDESFKDE
                     QRALVAPAEAVFLNAKLEADLAELDEDEALELLQTVGQEEPGLATLAHVGFRTLGLQTY
                     LTAGPKEARAWTIKKGATAPEAAGVIHTDFQRGFIKAEVISYDDLLTTGSTADARAAGK
                     ARMEGKDYVMQDGDVVEFRFNV"
     misc_feature    complement(23306..23321)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.72"
                     /tool="antismash"
     gene            23458..24207
                     /locus_tag="DQ392_RS06475"
                     /old_locus_tag="DQ392_06465"
     CDS             23458..24207
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042451.2"
                     /locus_tag="DQ392_RS06475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DQ392_06465"
                     /product="DUF6542 domain-containing protein"
                     /protein_id="WP_114014500.1"
                     /transl_table=11
                     /translation="MEQRSAHPTQHGPYELYGDPEPYEPSHRYADEPRQGHAPADLAAG
                     VAGGEVAAGSVRIRRRPRLPRPAAAPSSSPPPPPPASGRGGVQGDRRPPHRPAPSGEGA
                     PPGARGAAPGRLPAPRLTGLGVGVFAMLLMAAFGALARLLSSGVPVAYGSAFVLVCVAL
                     ALWVRPAELFAAPVAMPLAYTVGLFLVGGSGKGVAGVLQDVFTGLALHAVWLYAGTLLA
                     GLIVLVRKTKLVLERRRRRRSKAPQGA"
     misc_feature    24551..24566
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.66"
                     /tool="antismash"
ORIGIN
        1 ttcggtcggg tccggggcca cggcgcccga ctcggggcgg ggcagctgga accagacggc
       61 cttgcccgag ggcacgcggc ggctgcccca gcccgtgctg agcaggtcga ccagttggag
      121 gccgcggccg ccctcgtcgg tgtcgtgggc gcggcggcgg cgcggctgca cctgcccggc
      181 gtcccacacc tcgcacacca gcgtgcgctc cagcagcagc cgcagcctga tgttgccctc
      241 gccgtaccgc agcgcgttgg tgaccagttc gctcaccagc agctccgtgg tgtcgccgag
      301 cgcttccagg tcccaggcgg tcagctgttc gcgggccagc tcgcgggcgc gggcgaccga
      361 gcgcggctcg ggcggcagcg tccagtcgcc cacgctgccg ccgtccaggc cctgcacccg
      421 tgccaccagc agcgcgatgt cgtcctcgcc gtggtgcacg ttgagggtgc gcagcactcg
      481 gtccgcggtg tcctccagcg gctcggccgc gtcggtgagg gccgagcgga accggtcgag
      541 gccctcgtcc agcgggtggt cgcgggactc gaccagaccg tcggtgtaga gcgcgagcat
      601 ggcgccctcg gggagttcga cctcgacctc ctcgaagggc tcgccaccga cccccagcgg
      661 cacccccttg ggcacctcca gcagcagcgc ggactcgtcg gcgggctcca gcagaatggg
      721 cggcaggtgc ccggcgttgg cgaacgtgca gcgccgcgag accggatcgt agacggcgta
      781 gatgcaggtg gccaggtaga cctcggacag atcggcgtcg gcgccacggt aggcgcgctg
      841 ggtgtgctgc tggcggcgcg cgtcgcccag gccgcgggcg atctcgtcga gggcgccgag
      901 gacctcggcg ggctccatgt cggtcagcgc cagcgtgcgg acggcggtgc gcagttcgcc
      961 catggcgacg gccgcgcgca gcccgcggcc catcacgtcg ccgacgacga tggcggtgcg
     1021 gtggcccggc agttcgatga cgtcgaacca gtcgccgccg acctcggtgg ccgggttgcc
     1081 cggcaggtag cggcaggcga tctccagtcc ggccgcctcc gggtcgcccg gcggcagcag
     1141 gctgcgttgc agtatgaggg cgcgttcgtg ctccctgcgg tagaggcgcg cgttgtcgat
     1201 gcagacggcg gcgcgggcgg ccagttcggc ggcgagcgcg ccgtcccgct ccccgaaggg
     1261 ctcgctgccc ttggcccggg agaactgcgc cagccccagc acccggtccc tggcgaccat
     1321 gggcacggcg agcgtcgact ggacgacggc gccgaactgg gcggggacgc tgccgtcctg
     1381 gcccgggatg ttctgcacgc gcccggtgcg cagcgcggtg gcgtagggcg agtgctcggc
     1441 gtagcagtgg gtggagccga cctcggcggg ctgtcccggc tgcgcgccgc tcgcgggtcc
     1501 gctgccgttg cagcggaccg ccgcgctctc gcctctcctg gcttcctcgt cgggcagcgc
     1561 gagggcgtag ggcgcgtcgg cgacggcgct ggcgaaggcg actctgcgca gttcgccgcg
     1621 gggtgcgccg aggggctccc ggcgccgcct gggcagcacg gggcgcgggg tgtggcccgg
     1681 tgcggcgccg atgccacggg ccggtcccgc gtcgccgaaa ccgtcggcgt cgtcggggcc
     1741 cggcggtccg acggggcggg gttcgtcccc cgcgagcacg ctctcgtaca gatcgacgga
     1801 ggccaggtcg cagaactgcg gcactgccac gtccagcagt tcgcgggccg tggtctccaa
     1861 gtccagtgag ttgccgatcc gcgcgcctgc ggcgttcagc agagccaggg cacgacgtac
     1921 gtcgtcctgc ttaccggccg cctccaccgg gatatcgctc aatgccgccc cttccactgc
     1981 cggtgctcgc cccaggtccg agcagtctgg cagcccggag aggaatccgg agcccgctct
     2041 tcccgatcgc cacaagtctc cttgccgcga cgaggcaaca tgcgcacacc ccccgctgtc
     2101 cacgggggcc acctctgtct cctaaccagc gagcggggtc tcgaaccctg ggatgccgca
     2161 cggttcgcga gccgtccgcg tacccgcccg gcgccacccg gcgccatcgg gcccctggga
     2221 gcacacctca ctcgtcgagg gcactcagtc gagcggcagt tcgaaccaga ccgtcttgcc
     2281 ctccggcccg tgccgggtgc cccagcggcg ggcctgcccg gccaccagct ggatgcccct
     2341 gccgccctcc tgctcctcgg tgacgacccg ctcgcgcggc ggctcgggca tcgggtcgga
     2401 gacctccacg accagcacac gtccctgcgc cccggcgggc tgcccggtgt cgcgcaccat
     2461 ccggacgccg atcgggccgc gcgcgtaccg cagcgcgttg gtcaccagtt cgctcaccag
     2521 cagtacgccg gtgtcctcca gctccgccag gccccactcg tgcagggtgc gccgtacggc
     2581 ttccctcgcc cgccgcaccg cgtagtcgcc ggtggtgaac gaccacgagg cggcggtgtc
     2641 gccgggcagt ccgccgagcc gcgccatcag cagcgccacg tcgtccctgg tgctcagccg
     2701 cccgtcgccc gggccgccct gttcgcgcag cgccgagatg aggatgtcgc acgcgttctc
     2761 gatgccgccg cacccggtgt cctcgaccgg ccccggtgag acgtagccgc ccgacccgtc
     2821 ccacgagaag ccgggttccg gctccacgcg gcacctggag gggccggcca gcagtccgca
     2881 cacccggtcg atgcccgcgg tgatgtccgc acccctgctc tcgacaagcc cgtcggtgta
     2941 gaggacgagc acgctgccct tctcgatctc cacctccgtc aggtcccagg agccgtccag
     3001 cgccggcccg attcccaggg gcgtgcccga ggggacgtcg acgggccgcg cccggcagcc
     3061 gccgtcgggc tcgggcgtga cgagcagtgg cggcacgtgg cccgcgctgg ccagggtgag
     3121 cactccgcac cgcttgcccg ccgaggtggg cgccggctcg tagacggcgt acaggcaggt
     3181 ggccatcatc ggctcgtcgg ggccgtggga gaggtcgtcg ccgacggtgc tgacccgggc
     3241 gagcagttcg tcgggcggca ggtcgagccc ggccagggta cggaccgcgg tgcgcagccg
     3301 gcccatggtg acggccgagt gcagcccgtg gcccatcacg tcgcccacga cgaaggcgac
     3361 ccgcccgccc ggcagcggaa tgacgtcgaa ccagtcgccg cccacctccg tgccgctgct
     3421 gccgggcacg tagcggtagg cgaggaccac gcccggcggc tcggggatgt gctgcggcag
     3481 caggctgcgt tgcagcatca gcgcgccctc gcgctcgcgc gcgtagagcc gggcgttgtc
     3541 gaggaaggtg gcggagcggt cggccagctc gacggcgagc gcccggtcgt cgtcgacgaa
     3601 ggggtcccgg ttctctgcgc ggctgacgac cagcagcccg aggccggtgc cgcgggcgcg
     3661 cagggggacg gccatcagcg agtgcacgtc cagatccaag gtggcgtccg tcgtggggtc
     3721 gcccgccctg ctggcgcgca ggatctcctc gggcgaggtc gccagctgcg gctcgccgct
     3781 gtccagcgcc cgcccgagca gggagtcgcg cgcgtagacg atctcgctgc cgagccgcag
     3841 cagccgctcc acgcgctcgc ccgcgtgccg ggcggcgaac cccagcatgt gcaacggggt
     3901 gcccacgggg atgaccggct cgggcaggtc gcccccggcc gcgacctcgc cgcgcagcag
     3961 cacgcccgcg tagtcggcga agcgcggcac gagcgccccg gtgaccgcct ccgagatcgc
     4021 gcggacgtcg agccggtcgc ccagcgccac cccaaggtgg tccagcagcg cgagccggcc
     4081 gcgcgccgcc tccgccttgt cgagcgcctc cagccgctcg gtgacgtcca tgacggtgca
     4141 gctcaccccg aacacctcgc cgccgcggtc gctcagccgg gcgtaggaga cggagcgggc
     4201 accgccgccg tcgagcgagg gggtcaccac gtcgacgacg gagcggccgg tctccagcac
     4261 gcccgtctgg atctgcatga cctcctcggc catcgcggcg ggcagcagcg cctcgaccgt
     4321 acggcccacc aggtcggtgt ccgcggcgtc caccagccgc agcagcgcgt cgttgtagcg
     4381 cacgaggcgc cgttccgtgt cgaagagggc gatgcccagg ggtgaggagg cgaacagggc
     4441 gtcgagcgcc gccagctcgt gctcgacggt ccgcaggcgg ctggtctcca cgatgttgac
     4501 caggacgaac ggatggtgct cggtgtcccg cagcagcgag ccgcggccct cgacctcgac
     4561 gacggaaccg tcccggtggc gcatgctcag gttgccgcgc caggtgtgcg tacgccgcag
     4621 cgcttccacg cgggcccggc gttcctcctc gccgctgacg atgagctcct cgatggggcg
     4681 gccgatcgtc tcctcggccg gccagcccag gatctcctgc accgcggggc tccacaccag
     4741 cacgtctccc cgcccgtcga gcatgacgat cccgatgcgc agcgtgtcga gaagcggggt
     4801 cgctcgtcgc gccccgccgg cgggttcggt gctcacacgg cccacatccc cggtcgggat
     4861 cggatggcag gctcggccgg tcggcctccc ccactcaggg ccgggcagaa ccggtcaagg
     4921 tgggagaact acccacactc gcgccgacga ctacccgctg accgcctgga ccgacccgtc
     4981 ggaccgctgg tgctccacca gatagccgtc accccgttcc cccagccgct cggcgaggtg
     5041 cagggcctcc gcccgggtgg cgtagctgcc gacgcggtag cgattgccgt ggcagtcctg
     5101 gcgtatgagc cgccagggcc gcaccgcctc actgtcgccg ctcacacttt gcatatgccg
     5161 gagcctacgc ccgaccctca cgcaccgcat tcgactttgc acaaagggcc agcgttttcg
     5221 gccaccagtt cgcctcgccg gacgcgcggg cgaccccagc ggagcgccgg tggtgacgga
     5281 gggcgacgca tcacctcacc gtcccccacc cccacgggaa ggcgtcaccc cccgagcagg
     5341 tgacgcgtca cctcaccggc aggtggtacg ccagcttgaa gcggtcggcg ggcaccacca
     5401 catccgccgt ctccacggca cgcttccccg cgaagtacgt ccgcgccacc accagcaccg
     5461 cgtgccccgg aaccccgccg agcgcggcca tctcctcggc cctgccgggg cgggagccga
     5521 cctcctcggt gacgttgtcg accaccaggt cgatcgccgc catccgctcc accacccccc
     5581 ggccgcccag cggcccctcc tccggaagca tcacaggcgt ccgccccgtg agcgccagtg
     5641 gctcccacga ggtggacagc atcaccggct ccccctccac ctggaagacg tagcgcgtgc
     5701 gcatcacctt gtcgcccggc tcgatgaaca gccgctcggc ggtctcgtgg gaggcctcct
     5761 cccgctcgct ccgcgactcc caggtacccc gcacccgctc gtcggactgc tcctggcgga
     5821 agggggtgca ctcctccatg gtccggtacc ccgtacgcgc gacgcggcgc gccgagggca
     5881 actcccgcac ataggtgccc gagcccgagc ggccctcgac cagcccctcc gccatcagga
     5941 ccttccgggc ctccagcgcg accgtgtcgg agacgccgta ctcctcacgg atccgggcct
     6001 gcgaggggag ccgggcgtgc ggcggcaggg agccgtcgga gatcttcttg cgcagatccg
     6061 aggccacccg cagatacgcg ggctgttcac cgaatggcac gagtgccctc cccgtttccg
     6121 gcctgccagc gcgaacgctg ggtcgtgcga gtgatgctga cggtcagcaa cagcttggca
     6181 acagagggtt gttggccgca acggtcggcc aaagtttcac ccgatgtgat gagaccctgc
     6241 tcagggccca cacattcgac gccacgggca tatccggggc acatccgatc ggcatgcaca
     6301 gccggcacac gacaggcacc cgcccgcccg tccactccgg cccgcccggc ccgcccgtca
     6361 ggactccgcg ccgtgaccgc ccgctccgga cgccccctcc cccgcggtct tcgtctcccc
     6421 gcccgtctcc gcctccccgg cgggctccat cgcgaacagc accatcgtcg cgctgacccg
     6481 taccgccccc tccgtgcccg gcgggagggc ctggtcgtgg aggactccgc ccagcgccct
     6541 ggcgcgctcg cgcacgtcct cccacacctg cccgggcagc cagacctcgg cgtccgtcat
     6601 ctcgcccggc acggaggtgt cgcgctgcgc cgtacgccgg cgcaactcct cgccgagggt
     6661 gccggagagc gccagatagg tgccgactcc cccggcggcg ccgagccggt caccgctgtc
     6721 ggggtcgtgg cggtaccgct tggccgtacc cccacggacc tcgacctcgc ccgccgcctc
     6781 gacgagcccc gccgtgtgca gcctgcgcag gtggtagctg acgttggcct gggactggcc
     6841 caggacccgc gccgcctcgg cggcgctgta ggactggccc gtcagcaggg agagcagccg
     6901 cagccgcaac gggtgggcga gcacccgcag atccgcgacc gcggcgcccg ccggcgcgtg
     6961 agaagccggg tccgcagcgg gggcggcggc cggaggcacc tgggcggcct cggggccggg
     7021 ccgcgcaccg ccgcggggac gagaggacat cgcgccagtc tccctcaggc ccgcgtctcc
     7081 accacgggcg gcccggccgc cgggcgcgac tgccccgtcg tcagcccccg cacctggcgg
     7141 ctgcacaggg cgcccaccgt cgccagggtg acgagcgcga ccccgcacag caacgtgggc
     7201 cgcactccga agcgttcggc gaagggtccg gcggccatct cccccacggg aagggcgagg
     7261 gtcgagccga gcgcgtcgta ggagtagacg cgtgccagtc tctcctgggg cacgttctcc
     7321 tggagcgaga ggtcccaggc gacgccgaac tgctcgatgg cgatgccgtt gatgaacatc
     7381 gccaccacca gcacggccac gtccgccgac tgcgcgagcg cgacgagcgg cagcgcgtcc
     7441 agcacgacca ccgccacgcc gagccgcagg gcgtgccgcg ccctggagcg cgccaccagc
     7501 accccgccgg ccagcgcccc ggccatctgg gtggccaaaa cgaagcccca cgccgtgcgc
     7561 ccgaacgtcg cgtcggcgac ggtcggcccc aggacctgga tgcccccggc cgcgacggcg
     7621 ttcaccacga agaactggag caccaccacc cacacccagg tgcgtgagac gaactccttc
     7681 cacccctcgc gcagctcccg ccacgggcgc gcgggcgcgg cgaccgtacc ggtctgctcc
     7741 cgcacggacg cgcgttcccg tccggccagg cggaaggcga gggacgcgcc cgcgaaggcc
     7801 gccccgtcga gcaccattcc ccaccccggg ctcgcgacgg cggccagcag cccgcccagc
     7861 gaggtgccgg cgatcatccc ggcgttgacc cccatccggg agagcgcgtt ggcgggccgc
     7921 agttcgtcgg cggggacggt gagcggaatc agcgcggccg aggccgggac ggagacggcc
     7981 gccaccgccc cctgcaccac gctgaggacc agcagcgccc ccatgggcgc ccggcccgcc
     8041 agcagggcca gccccacacc gctctgcacc agcgcggcgg cgagtgcggc gccctggagg
     8101 acgagcgccc ggggcagccg gtcggcgagc agcccgccga acagcagcag cacgacgttg
     8161 ctgaccgagc gggcaccgac gacgaggccc acgtcgacgg cggaaccgcc catgtccaag
     8221 acggcgaagg cgaggacgac gggcgccatc gcgttgccga agtacgtgag ggcacgcccc
     8281 gacgcgagcc cgcggaaacc gcgccgccgc atcagggcgc gcagcgggag gcgttgcgcg
     8341 ctgtcggcgc cccggccacg gggccgcgag gaggcgggag gagtcacgcg gtgagtgtgc
     8401 ggcacgcgac cctgcaccgt caaacacttc ttttggggtc gcggacggag aaggccctcc
     8461 gccccaggac ggagacgggc ccgcccggtg gacggaggcc cccgcgcgcc gcgcctgtca
     8521 ccgtggaccc catgagcacc ccgaccccga cccgccacag ctggccggac catctggccg
     8581 ccggcgcggt ccgtttcgcc cgcccgacgg cacgcttcga cgccgtacgg gccttctacg
     8641 tcgacgacct cggcctgccc gtcctcgccg agtggcgcga ccactccggc tacgacggcc
     8701 tcgtcctcgg cctccccggc acccccgtcc acatggagct cacccagcac ggcgccccgc
     8761 cccgcatccc cgagccccac cccgagaacc agctggtcct ctacctggag gaccgcgcgg
     8821 cccacgaccg ggcggcggca cacctcgcct cccgcggcca ccgtcccgtc accgccacca
     8881 acccgtactg gcccacccac ggcgccaccg tcttcgcgga cccggacggc tggcagctcg
     8941 tcctcgcccc ctgggtcttc ggccgcgacc cggtaccgga cgctcgccgc tgagcaacgc
     9001 ccgggggcgc gcgcggcgtt cggccgaggc gaggagtgca cccccgccac ccgggccggc
     9061 cgcgggccac ggcgtaccgt acggctgcga gcccgctgcg tacccgcccg agggaacagc
     9121 ggcgcacgga acggcgcggg cccccggggg ctcacgcgtg agcgaggagg agacagggac
     9181 catgaccacc gtgagcggaa gcaccgtcga catcccgacg cgggacggca ccgccgatgc
     9241 ctacctcgtg cacccccggg gcgaagcccc gcacccggcg gttctcctct acatggacgc
     9301 cttcgggatc cgcccggctc tgcgggcgtt cgccgaccgg ctggccgcgg ccgggtacac
     9361 ggtgctggtc ccgaacgtct tctaccgcac cgggcgcgct cccgtcgtcg agctgcccga
     9421 cttcatcgac ccggcgcagc gccccgacct cttcagggac ctggggccgg ccttccagac
     9481 gctgacgccc cagaacgcca cgcgggacgc cgacgcgtac ctgcggtacc tcgccgggct
     9541 cgcacaggcg gccgaagggc ccgtgggggt gacgggctac tgcatgggcg cggcgctggc
     9601 cctgcgcacg gccggcgccc accccggccg ggtcgccgcc gccgcgggct tccacgccgc
     9661 gaacctggcc accgacgccc ccgacagccc gcacctgtcg gccgaccgga tcaccgcgga
     9721 gctctacttc gggcacgcgg accaggaccc cggcatgccg cccgagcaga tcgagctcct
     9781 ggagcgcacg ctcacctccg cgggcgtccg ccaccgcgcc gaggtctacg agggcgcccc
     9841 gcacggcttc acccagtccg acaccgccgc ccacgatccg gcggcggagg aacgccactg
     9901 ggaagccctc ctcgacctgt tccgcaggac cctgtgacag ccgtccgcag gactgcgacg
     9961 gccgtccgcg ggtgagcccg gagcccaccc gcggacgcgc tcagcgcggt gcgtgcgcgg
    10021 cccggtcgag gaggcgtcgc cacaccccgt aggagtccgc ctcctccgcg ggacgcagcc
    10081 ccatgcggtt gcagtgcatg tgcagcgcgg ccagcacgat gtcgccgcgg tccgcctgga
    10141 gcgcgccgtc ccgctccagc tcggtcatcc ggcgggtgag ccgctccgcg gccgggcgcc
    10201 acgcggcagc ggcccggtcc agcagtgcgc gggccggacc gtcctccgta cgggcggccc
    10261 acaggccgcg cccggccctc cggtacaggc cgcctccggc gttgcgcgac gccgcgagcc
    10321 gggcgagtgc gtggcgcgcc tcgggctcgg ggaccaggag ggcgcacagc ccatcgaggg
    10381 tgagggcgac cagcgcggca cgttcccggg acgcgtcaag accgaggtgc ggcagccccg
    10441 gcaggccggt cggtgaggcg cgcaggtccg cgaggagctg gacgacggcc gcactgtcct
    10501 gccggaagaa ctcctcggcg tcggcgatca gttgggggcc gccgtaccgc tcgacctcgc
    10561 gccggtaggt gacgtaggtg tggtccgtga tgtgcccgcc gccggcgagg tcgtacgccc
    10621 aggcggtgac ctcgcccagg acgtccgccc gcgtgtcctg gtcgggcacg aagaaccgta
    10681 cccgcaggtg aggggccgga tcgccgtagc gcaggaagaa cggcgccgcc acgccgtacc
    10741 gttcggacag ccgccgggtg agaccggcca ggcccacgcc cagcagcgtg tcgtgcgcgt
    10801 ccggttcggc gtagagcttg acggccagcc agtcgctgcc gacgcgcttg acccgtgcac
    10861 cgggctcctc ggcggtgtcc gcggccttac ggggccgtat gtgccgggcc acccggcccg
    10921 ggtcctggcc ggtccgcacg aggggcacca cgacctcgga ggcgtacggt tcgccgtcgg
    10981 cgtcccgcaa gaagccctcc ccgggtgcgg gcagtacctc ctccaggacg agcccgtcct
    11041 ccggcgcccg ctccaggctg tcgcgcagct cgcgcaggca gggggcgctg gtgaggtcga
    11101 gcagcagggt gttgtcgctg ctggcgatgt tgaccagccg gggcaccatc cacgtctgcg
    11161 cccaggcgcc gaaggcgtcg gcgaacgccg ccagtccgtc cccgtccccg tcgccgccgg
    11221 tggacggcgg gaactcttcc gcccgcagcc gccaccgcgc ccggcgcagc accacatcgc
    11281 cccgttcgac gcggggcagg aacggcatgg tccagctcag cgcgtcccag ctgaaccacg
    11341 agaccgtgcg ggagagggac tgggagacct ccagcaggaa ccggcagggg tcgggggcgc
    11401 ccgcccagtt gagcatcgtg cggtcggtga cgtgcagacg ccggcccagc atgcggctgc
    11461 gcaggtagag cttcccctcg gccacgccga cgaggacgtc gtccagccgg atcacccggt
    11521 cctcgtcccg gccgggcgtg acgttgaccg gcagctccca cgtgtgtgcg gtggggcgga
    11581 tcgagacgtt gatggagcgg gcgtcctgcg gcagggagga cagctcggcg cagacggcgt
    11641 cgccctgccg cgtctcctcg gcggcggcca gctgacgcag cgacgcctgg gccccgtcgt
    11701 cgaggagatc gtggaagcgg gagaaggtcc ggccgcccgg caccaccccg gcggtgccgc
    11761 agacggcacg ccagtgctca cgacccgggc ccggtgccac aagcgtgagg tgcaggtcga
    11821 tgaggggcat cggcggcctg tggtcgtcct tcggcgccga gacctccgcc agctcctcca
    11881 gcagccggtc gtcgagctgg acggcccgct cccggcgggc cagcgcaccg gcgaccagcc
    11941 ggtccagcac ggccttccgt gtcggccccg cgggccggtc cgacaggtcg acgggctccg
    12001 gcacgacacc gggcagcggg tacgcctgcc ccggcgagcg gtacctgcgc ggcgggccga
    12061 gaccggtctc gggggtcagc gcctccagca acgggatctc ggagcggtgg ccgtaccgct
    12121 cggcgaaggc gtcggcgtac tccttgagat gcggcgggta acggtcctcc gcgcccacgc
    12181 gcagcagcac gcgggcggcc tcttcggcca ggtccgccac ggcccgtgga aggaccaggg
    12241 acccgtcgcg gttcagcgcc gcgtcgatct ggagcgtcgg gcccatgtgg ccgccgacgg
    12301 cctcgggcat cggcgcgctc gccgccccga gcagaccgcg tgccgggatc tcaccccggt
    12361 tgaaggcgtt gacggcggcc tccaccccgt cgatcgcccg cgccacggcg ggctcggtga
    12421 cgggcaaaag caccgagcgc agcagtgagt cgttgccggc ggcgtggggg accagcagcc
    12481 gggggcgctc gacggtgatg aggatgtcgc tgtcgaagag gccgtcgagc agggccgcga
    12541 cgcgctcggc accggcccgc ggataggtct cggtgagcgc ggcggtcagt tcgccgagcg
    12601 tcgtcggcgt acgggcgagg tcgagtacgg agcgtatcgg cgcggtgagc cgcacgctga
    12661 cggagcgccg gcccctgggg gtggggcgct gctcgtcgcc gtgcgcggcg gtccgggcgg
    12721 ccccggcgtc ctcgttgagt ccgtagccct cggcggtgga cagccacacc cggccgcgcg
    12781 agacgtggag caggtcgttg cgccgcaccc gcaggtcgtc gcgggagcgc tccgcaccga
    12841 aggcgagccg cttcaccagg tgcatgaccc acccggagtc cgcgcgtgcg cgggccctgc
    12901 cgagggcgcc gtgcccgagc cgggtgcgct gctcggcgcc gaacacgccg gtggtcacgc
    12961 ccgcgaacag gccgaacggt gtcgacctga agctcatccg gttcagataa cggccaagac
    13021 cgcgcacggc cttgcgccgg ctcttgccgg tgagggtgtc gaaccgctcg acggcgtccg
    13081 ccaggtcggg cgaggcggcc cgcacggcgt cccgcacgcc cggggcccac cacagcttga
    13141 ggagctgctc cgcgtagttg tcctgccagg cgcccgtacg cagggtctcg gcgtccgccg
    13201 gcagcgaccc gaacacatcc agcagcgggc gtgcgggcag ggcaggcgcc ctgagcatga
    13261 agaacccgca ggtctcgtag gtgtcggccg cttcgctcac gtctccccca tgccccggtc
    13321 ctgtctcgtc tccgccccgg ccccacccgg tgcgtctgcg cgcggtgcgt ctgcgcgcgg
    13381 gagcctgggg gtcaggaaca gcagttcgtc ccaccctgcc gccgcctcgg acacggcgcc
    13441 caggagggcg agcagcaccc ccgccgcacc gttcagcaat ccggcgctgt gctcctgctt
    13501 tccccacggg tcgtagtcag ggaagaggta gggatggtcc tcgtccgcga acgagcacat
    13561 ccgcgacagg aaccgctcgt gcatgtggaa cagttccggc acaccggtct gtgcggcggc
    13621 acggccgtag acggtcacca gccccgccag cccgtggcac agcgtgggcg agttgacgcg
    13681 ctgctgctcg gcgggggtgc gttcgaggcc gaggagcgtg gccaccgcga ggtcggtcgg
    13741 ctccgggtca ccgcaggccg acgaggccga cagcagggac gcggcgacac cgggcggtcc
    13801 gtagcaccac gcgctcctgg ccggcacctg cgcagcaccg gtgtcggggc ggcgcgagtc
    13861 cgggtggggc agcaggaggt tggcccacgc ggggtagtcc agaccgtcga tgcgcagcgc
    13921 atcgagcgtc cgggcgagag cgcggacccc ctgccgcacc cggtggggcc gcgcggcggc
    13981 cgggtccgcg gagccgctct cggagtccgt ggtgccggct gcggagccgg ccaccgggtc
    14041 cgccgtgctg ccgggcgcct cggcgatgtc ggggcggctc agggcggcga gaatgcccgg
    14101 cggcccgtgg gcgaacccca ggttgtagac gccgtcggga aagttcttca cgtacccggg
    14161 aaggggcgtc ggctctccgt cggggcccgg aatgctggga aagtgggagg gcgcgcagaa
    14221 ccatctgagc gggccgccgt catcccgggt cagctccacc aggtagtcga cgaggcggtc
    14281 cgtggcctga ccgaccgcgt ccgtcgcgcg cccgccgagc acgtccgctg ccttgaggag
    14341 cgcggcgagc cagcccgccg cgcctccgat gacgtcgtag tcgtgtgagg cgacgctccc
    14401 cgctgcggtg tggagcgtga tcgccagcgt ctgccgggcg agccggtcgg tcatcgtggc
    14461 gagcgtgggg aggtagcggg gctccatgcg ggcgtactcg gtcaccgccc agacgacgcc
    14521 cgcggtgccg aggtagagac cgggcgcctg caagggagcg gtggcactcg cctcggcggt
    14581 gcgccgcaaa tggatcctgc ccgcggtgaa gtagcggctg tcgtcgaaga cttcggcggc
    14641 gtaccggaga gcgagcgcga tgccgggggc accgtcggcg agatcggctt tccccgcggc
    14701 gtcgccggcc gactccagga gccggtcggc cacttcacgc gccagccgca gaacctcgtc
    14761 gtcggtcact ttccccacgg aacgggattc catggttccg ccgttctctc tttcgcccct
    14821 cgacagcgcg cggccgcccc tcggaagggc gcggtcatac atgcgggaag cacgtgccca
    14881 tacgcgcgcg aggcacctga ccatcgccgg aagaacatga ccatacggag ggctcagaag
    14941 cccctgtgcg gggaccgcgg ggccctccgc gtggctccgc acgggtgtgc gtcacatcag
    15001 gtgcgacgtg tcagcagcac ccgctgagtg tgtcggtgca cagcgacgtg cgcgacgtcg
    15061 cgcaaccgcc gttgttcgtg gcggcggcgg aactggtcga aacctccgcg tgccccacac
    15121 gcaggtcgag ggagaattcg tcttccagca ggtcttcgct catcgtgttc ccttcgataa
    15181 ggggcccgta cgggaattcc ggagaaatcc ggcgatgatg aatgccggat ttcccggagc
    15241 ttcctggaac ctagtggagc gccaggagaa gcgtcaacac atcggccacg gcggtcactt
    15301 gagcaaccga tgcgccgccc ggggcaagct cctaccgggg ttgagcggcg gtgtcgtcgc
    15361 gcggcgcggg gacaccctcc gccgaggacg cggtgagccc gtactgtgcg gcctgcgcgt
    15421 cgaacatgcc ccggtacaga ccaccgggcc tgcccatgag ttccccgtgg gtgccgcctt
    15481 cggcgatgtg cccgcggtcc aggacgtaga tgtggtcggc ggaggcggtg gcggcgagcc
    15541 ggtgggtgac cagcacgacc gcgacgccgc tgtcggccag ggtccgcagg cggtcgaacg
    15601 cctcgatctc ggcgtgcggg tccagcgccg aggtcggctc gtcgaccagg aggaagggcg
    15661 caccccggta gaggctgcgc gccgtgccca gcttctgcca ctgtccgccc gagagctgga
    15721 caccgcgttc gtaccccttg aagacgatgg agtcccagcc gtgcggcaga ccttcgatca
    15781 gctcgtccac accggcggcg cgcgccgcct ccttcaggcg ggccgcgtcc cgggggcggt
    15841 cccctgcgcc gatggcgatg ttcgccgcgg ccgtcatctg ccagttggga aagtcctgcg
    15901 tcagcatccc gacggaccgg aagacgtcgg cacgggcggc ttcccgcacc tccacccgct
    15961 ccccttcccc gccatcttcc ccgtcccctc cggccttccc gcccacccac cacacctcac
    16021 cgctgtcgga cagcagcagc ccgcccagga tcctggccag cgtggacttg cccgacccgt
    16081 tcgcgcccac gagcgccgtc acctcgccgc gccgcacgga cacgtccacc cggtgcagcg
    16141 cgggcaccgt cgcccccgga taggtgaagg agacgtcccg gacctggatc tcccgtaccg
    16201 gcgcgggcag cggcctgccg gtacgcggaa tggcgtgccc ggacgcgatc tggatggcct
    16261 cctcggtgtc gctgagccgg agcatctcct cgtacatccg gttgacctgc tgcaccagcg
    16321 aggtgagccg cgcggtcgag gtgcggatgg cgacgacggc ggtgcccccc accgccatcg
    16381 gcagaccacc actggtcagc agccaccaca gcacgccgta acagcccacg gacgccaggc
    16441 ccgagaacgc ggcggcggcc aggtcggtcg cggcctgtgc ccgggccaga cgccgctgct
    16501 cggtctccat cagaccggac atctcctcgt acccgcgcag cagcagcgag cccgccgcgt
    16561 gcgccctgat ctccccggcg gcgtgcggca tcgtcagata ctggagcagc gtggcgacgg
    16621 ccctgcggtg gtccacccag tgccgacgcg acacgtactc ccggcgcgcc gagcgcaccg
    16681 ccccccacgc cttcggcagt gcgatggcca gcagcatcgg cagcagagcc cagtgcagcg
    16741 aggccagcac gaccgcggcc gccaccatgc cgatcaccac gttggcgacc cccacggaca
    16801 ggctgagcat gcgccgtgcc gagtccgtcc cgaactttcc cgcgtccagg tggcgttgca
    16861 cctcgggccg ctccgtggcc gcgatctcca cctcggtcac cgaccggtag taccggagcg
    16921 aaacagcccg ctcgacctgg ggctccagcc gtcccgacat cgctgtcgac caggccgtca
    16981 gcagcgccat ccccacggag acgagagcca gcagcgcgag cgccggaagc gactcccgca
    17041 gcttgtcgtc cgtcggcccg ttcgcgaaca gactgctgag cacaccgttg acggccacca
    17101 gcccgaacgc cgtcgtcagg ccctggcccg cctgcgcgac gaccacgcct gccagcgcac
    17161 gcgggtcggt ctcccagccg gcccgcagga ccacgcccac catgcgcggc agcgccgccg
    17221 ccatgtgcgc gaaccgcagg cgcgccaccg cgccctcgtg ctcgacgaac gcgtcgtccc
    17281 agcgcaggcg gccgccgaac agctcccgtt cggctgccga gaccccgcca tgggccgccg
    17341 gctccgcacg ccgacgccgc ttccgtcccc ggctgcccgt cccgtcgggt gaggcgggcg
    17401 ccgactcgga accgcccccg ggccacctca catcggcctc ccctgcggcc ggcgcaccgc
    17461 gtgccgacac gcggcggtgt cccgccggac acgtgcacgt acgacatgac cgatcccgtc
    17521 ggcgcgacgt ggggtcgcgg ggtctccagc ggtcacagag cctccagttc gagagcgtcg
    17581 ggcaggaagc atgggcgtac gccgaggtcg ggcaccacga gcggagcgga cagcgtccca
    17641 cgggtggagc cgggacggcg gcgccggtcc ttgccttcgt cagtcctcgg tgtccgccga
    17701 gggggacgcg ggcgggggcg tacggccggc gaccccgatg aactggacgt cgagctcgtc
    17761 ggcgatctgc tccagggtgc cggcgagggc atgaacggta gtcggttcaa ggcgcacgga
    17821 gtcgtggctt tcgccggcgc ggacgggagt gccgtggcgc gtgctgtgcg cccaggaccg
    17881 cgcgatggag cgcaggaggg ccgtgacgtc atgggcgggt acgctcagcc gcccgtccgc
    17941 ggtgacgtcg acccgcggcg ccgccagcgg catgtcgtcg tcgtccgtgc tcatcctcag
    18001 tctcctggat tcctgcgttc gcggctcgcg ggtttcgccg ctctcgccgc ggtgggccgt
    18061 cggggccttc cggggttctg tgcggctggt ggcgtcggat gtcgtggacc gagccgggtc
    18121 ccgcgtgccg cgacacggcc ggtgaaccgt gtcgcggcgc gtgccaccgc gtcctgggac
    18181 atgagcggtt ccccgacaag cgtgagcggt tccccgacag gtgccggcgc tctccagccg
    18241 tctcccggca ggtgccggcg ctctccagcc gtcttccgac gtcgccggtg ctttccaacc
    18301 gtgtctgtcc tgacaggcgt gccgatcaac cggctcgcgc gggccgccgc ggcggtgtca
    18361 ccggccgtcc cggggagtgg agcggacgcc ctcctcactc cccggagtcc accaacgcac
    18421 accacacccc gcgctgcggc ccgccgtcga ggtccgtcca ggagacggtg acgtgaccga
    18481 gggacccctc cgtctccggc acgccgtccg gccggggcac gcgcaggaag cgcagccgcc
    18541 gaaggccgtc caccggcagg gccaggtcga cgtcgctgga acgcgacccg tgacgcactt
    18601 gcctgatccc cgcgtcctcc accaggggct cggccgcctc gcgcaccgcc accgtccggt
    18661 cgacggtgtc gctctcgttc tgtgcctgcg ggtcgacccg gcctgtcacc agcgcgtacg
    18721 tctgtgcgat ggcgacggga tcgtgagtgg cgtcgtagac ccagcgtttg cccaggaccc
    18781 cgtggtccaa cgtccctatg agcccgtcgt ccgcgccggc cagaggcgcg gaccgatacg
    18841 ccatcggcac ctggtaggtg accggttcgc cgccggcctc gtcgatgacc gccatgaact
    18901 cgacgcccac ctcgccggca gggtcgtcca gccggaagcc gcccacgttg acgagggcgg
    18961 ccctgtccgc gccggagacg taccacggct gggacggaag ccacgcctcg agcagttcca
    19021 gcttggtagg acgcagagtg gtgcggtaga tgatcgacac agcgggtcct ttccctcggc
    19081 tcgtgcacca catccttgca gccggggcgc cgcacagggc cgcaccgtgg ctgttcaccc
    19141 gaggccccgc cacggcacgc cggcgactgt cgccccaccg cggaatgggc cggcacggga
    19201 gccggcggcc cgcggcccgc atgccaccgc cggttcacca cgtctcgctg ccgggatgcc
    19261 cacgagagac gtcagctacc gggagcgggt cagctggtat gagccctccg agaggcatac
    19321 gcggtcgtgg ctgtcgatgt gaccgtccat gtgggagggg acgttccgta ggtaggcgta
    19381 ggcggacttg ctgaaccgga ccttgccgtt gccgaggtgg gtgatgcctt ccggttcgtc
    19441 gagaccggcg agccatctcg cgctgtcctc gtccatgagg gcggtgtaag ccatggcgga
    19501 cctccaagcc accgcagccg atgcggtcac gacggcgacc accgatgcca ggcggaccct
    19561 cttgtatctc atcgagcact catctcccct ggccccggct tcgcgaccac gaaagctatg
    19621 tgtccgctca tgaggtggtc aacagggcgt gacagcgcgg gcacttgcgt actcgagtgc
    19681 cctgcgcctg accgcgggcg cctccgcggc ggccggcccg tcggcgatgg ccgactcgtc
    19741 acggacgggg ccgggtcgtc gtcccaggcc gagggggatg cgcgccgtgc tgctccctgg
    19801 ggccggtcga gagggggcgc gatggccggc gaggcgcccg gaggccgaac atgatccgca
    19861 agcccggcgt cctgcggacg atctcgtagg tggcgatgct gagacagcac cccggaacca
    19921 tgatggcggg gaaggcgacg gcaccgtgta cgtccgtctg tagaacgtag tacgcgatca
    19981 cgatcaaata ggtttgatgc aggatgtaga caggaaaggc cgcccggctg aaatagtcca
    20041 tgaaggccga cctgcgatcg agataccgtt tcccgtatcc gagtacggcg aggagggtcg
    20101 cccagcagac tggatagtgc caggcggcgg acagaggatt cgcctgactg ccgatcgtga
    20161 atcgctcgat cagaatcccg atcgcacccg gaacggcgac gcaaagaaag acacgacgat
    20221 tcccttccag cgcttcgatg atcgagtcgt cggtggcgat gaggaatccg agcagcacgt
    20281 agccggcgta cacgaagatg ttctccccgc cgatctccgg gaggaacgac aacagcgcga
    20341 gcccggccgc cggcgcgaga gcgagaacag gtttgtccag ccaggtgggc gtgtaccggt
    20401 tccggaccac cgtgagcatg agggggagcg cggcgatcga gatgaggaac aggaacagga
    20461 tgaaccacag gtgggccggg gagatccccg taagaaccgt ccagtgggag aagtccgtga
    20521 agtaaggacc cagaaagtca gcgtagcttc cgccgtagcc gttgtggaac cgcatcgcgt
    20581 agtacgcctg cggcggcacg atgacgaggc agccgaagag gaacggtatg aacagccgca
    20641 gataccgctc cttcgcatag ctccgcgcgg aacgctttcg cagcgcgtag tagctcgaca
    20701 tccctgccag gagaaagagc agcggcatga accagaagga ggagatgttg accagggccg
    20761 aggagagggt gttcaccggc cctttgacgt agaactccgg gttgtcgttg aagatcctgg
    20821 ccgtatggaa cgggaacagg aagaggatgg ccaggttccg cagccagtcg atgtagtcct
    20881 tccgcttcac ttccgcgccc cctcggtcag ccagccgagc acggcacgca gcgcccgctc
    20941 cgcggtgtcg gcgtcgacgc cctcgcgatc gacgaggtgt tccgtcgcca ggccgttggt
    21001 caggcagtgc aggatcgttc cggccagctc ggggtcgacc ggaggggtga tcccggcgcg
    21061 ttcggtgacc gcccgtaccg cgcgcccggc cgacgcacgc tgagcgcggc gcatgggggc
    21121 gaccaccgcc cccgtcccct cgtcacggat ggcgcgggcg gcgatctcga gaccgagccg
    21181 tccccgctcg gtgtcatcga tgatccgctg tgcgacggca cgggcggcct gctcgatgag
    21241 cgcggggacg tccgcgcccg cgtcgagacc ggccatcacg tcggccagtt ccgcttcgga
    21301 gcgctcactg aggatcgccc cgaagagctc ctgtttgctg ccgaagttgg agtagacggc
    21361 gcccttggtg aagccggcga cccgggcgat gtcctccagc ttgctgtccg cgtacccgcg
    21421 ctcggcgaac acccgctccg cggcggcgag cagccggcgg cgcacctcgt cgcgagggag
    21481 gcgcggcacg ggccccggcg gatggctgtg accttctgta tctggcatgc acccatggtt
    21541 gcatacccgg aggtattcag tacccgcagg tatcgaacgg attggtgagg ctgccccacc
    21601 gtcgcccgcc ggcaaggggc cgcggtccgt gggacttctc cgcgccgcgt tcagcctgat
    21661 ctcgcacacc aactcccgca cctcgccggc atcgcgccac tcacagcggc caagcggtca
    21721 gcaaatcgcc agggccttag gcggcatcca accccggaca gtcggctccg ctgcgcgaga
    21781 ccgccacgac cggcacgggt tcgccggtga gagcggcccg gtgccgatgg caaacgtggt
    21841 gcccgcacgg tgagtttgtg ggcacgaagc cctggcggcc ggcctccaac gggacgggtg
    21901 cgacaacttg cggaccaggc cggacgcgcc ggagggggag agcggcgccg gctcagcgct
    21961 ccggggtcca tccgtggatc agctcgtgct gcgccaagtc cttgaagtag cggtgccgcg
    22021 accaggcatc gaggtcgccg atgacgatga ggcgccgacg aagggcccga ccgcgaagag
    22081 tcgggccctc cctgacctgc atatttgcca ggtcagggac gtggtggtta cccgtaccca
    22141 ctacacgttg aaccggaact ccaccacgtc cccgtcctgc atcacgtagt ccttgccctc
    22201 catgcgggcc ttgcctgcgg cgcgggcgtc ggcggtggag ccggtggtga ggaggtcgtc
    22261 gtaggagatg acctcggcct tgatgaagcc gcgctggaag tcggtgtgga tgacgccggc
    22321 ggcctcgggg gctgtggcgc ccttcttgat ggtccaggcg cgggcttcct tcgggccggc
    22381 cgtcaggtag gtctggaggc cgagggtgcg gaagccgacg tgggcgaggg tggccaggcc
    22441 gggctcttcc tggccgacgg tctggaggag ttcgagggct tcgtcctcgt cgagctcggc
    22501 gaggtcggcc tccagcttgg cgttgaggaa gacggcctcg gcgggggcca ccagggcgcg
    22561 ctgctcgtcc ttgaaggact cgtccgtcag ctcatcctcg tcgacgttga agacgtagat
    22621 gaacggcttg gtcgtcagca ggtgcagctc gtgcagcggc tcggcgcggt cggtgccctg
    22681 ggcgatgccg gcggagaaga gggtacggcc ctcctccagg atgtccttcg cctcctggac
    22741 ggccttgacc tgcggctgct tgtccttctt gacccgcgct tccttctcca ggcggggcag
    22801 gaccttctcg atggtctgga ggtcggcgag gatcagctcg gtgttgatgg tctcgatgtc
    22861 gttcttgggc gagatcttgc cgtcgacgtg gacgacgttc tcgtccttga aggcgcggat
    22921 gacctggcag atggcgtcgg actcacggat gttcgccagg aacttgttgc ccaggccctc
    22981 gccctcgctg gcgccgcgca cgatgcccgc gatgtcgacg aagtcgacgg tggcgggcag
    23041 taccttctgc gactggaaga gctcggcgag cttgccgagg cgggggtcgg ggacgcccac
    23101 gacgccgacg ttcggctcga tggtggcgaa cgggtagttg gccgccagca cctcgttctt
    23161 ggtcagggcg ttgaacaggg tcgacttgcc gacattcggc aggccgacga ttccgatcgt
    23221 gagcgacacg tggcgactac ttcccgtggc ccctcgcggg gttctccata gtggggtctc
    23281 ttggcggaca ggcggccctc gaaggccgac cacccagtct acggaaggcc ccgcggcgcc
    23341 ctcccccgac cgtgcttgct cctcccggtg gatcgcgggc gtgccggtcc ggtggcggtg
    23401 gcggatatcg cgtgtccatg accgccgggc cgggcacgta cgacctaccg tggcccggtg
    23461 gagcaacgca gcgcgcaccc gacccagcac ggcccgtacg agctgtacgg ggaccccgag
    23521 ccgtacgagc cctcccaccg ttacgccgac gagccgcgtc aggggcacgc gccggccgac
    23581 ctcgccgcgg gcgtggccgg cggcgaggtc gcagccggaa gcgtccgcat ccggcgcagg
    23641 ccgcgcctgc cccgtccggc cgccgcgccc tcgtcctctc cgcccccgcc tccgccggcc
    23701 tccgggcgcg gtggggtgca gggggaccgc cggcccccgc accgtccggc gccctccggg
    23761 gagggtgcgc cccccggggc gcgcggagcc gcgcctggca ggctgcccgc accccggctg
    23821 acggggctgg gcgtcggagt gttcgccatg ctgctgatgg cggccttcgg cgcgctcgcc
    23881 cggctgctgt cgagcggggt ccccgtggcc tacggcagcg ctttcgtgct cgtctgcgtc
    23941 gccttggcgc tgtgggtgcg gcccgccgag ctgttcgcgg caccggtcgc gatgccgctc
    24001 gcctacacgg tcgggctgtt cctggtgggc ggctcgggga agggcgtcgc gggggtactc
    24061 caggacgtct tcacggggct ggcgctgcac gccgtctggc tgtacgcggg cacgctgctc
    24121 gccgggctga tcgtgctcgt acggaagacg aagctcgtcc tggagcgccg caggaggcgg
    24181 cgctccaagg cgccccaggg cgcctgagga aaccacggcc ggcccggcgc ggcacccgca
    24241 cagcagtgtg accgtccccc gcgccgcagt gaccgccccc gccgtggtgg cggcaccacg
    24301 gcgcgatggc cgccgcggcg gcacggtggc ggtgccgccg ccgctctcag gcccgcagct
    24361 tgccggacgc ctcggaccgc aggtcgcgcc gcagctcctt ggggagcgag aactgcatgt
    24421 gctcgtcgac cggcttgacg atctccacct cgtcccagcc acgctgtgcc agccactcca
    24481 gcacgccgtc gaccagcacc tcgggcacgg aggctccgga ggacaggccg atggtctcca
    24541 cgccctccag ccaggtctcg tccagctctt cggcgttgtc gacgaggtgg ccgtccttgg
    24601 cgccgtgcgt cagcgccgtc tcgaccaggc ggacggagtt ggaggagttc ttggagccga
    24661 cgaccagcac caggtcggcc tcggccgcga cctgcttgat ggcggtctgg cggttctgcg
    24721 tggcgtagca gatgtcgtcg ctgggcggcg agagcaggtt ggggtaacg
//
