LOCUS       NZ_CP015163            50893 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Amycolatopsis albispora strain WP1 chromosome, complete genome.
ACCESSION   NZ_CP015163
VERSION     NZ_CP015163.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis albispora
  ORGANISM  Amycolatopsis albispora
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 9121443)
  AUTHORS   Wang,H., Chen,S. and Wu,Q.
  TITLE     Complete genome sequence and analysis of deep-sea sediment isolate,
            Amycolatopsis sp. WP1
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9121443)
  AUTHORS   Wang,H., Chen,S. and Wu,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2016) Zhejiang University of Technology, College
            of Pharmaceutical Science, Chaowang Road No.18, Hangzhou 310014,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera assembler v. unspecified
            Genome Coverage                   :: 138.17X
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 04:57:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,537
            CDSs (total)                      :: 8,472
            Genes (coding)                    :: 8,394
            CDSs (with protein)               :: 8,394
            Genes (RNA)                       :: 65
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 26 of 78
            Pseudo Genes (incomplete)         :: 54 of 78
            Pseudo Genes (internal stop)      :: 6 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:20:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 627053
            Orig. end                         :: 677946
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP015163.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..50893
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /region_number="4"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..50893
                     /SMILES="NC(CCCC(=O)O)C(=O)NC(CS)C(=O)NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..50893
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:30893](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..30893
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            321..1277
                     /locus_tag="A4R43_RS03195"
                     /old_locus_tag="A4R43_03135"
     CDS             321..1277
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020517497.1"
                     /locus_tag="A4R43_RS03195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03135"
                     /product="cyclase family protein"
                     /protein_id="WP_236808751.1"
                     /transl_table=11
                     /translation="MTAERQLPTQDEVLGYFETLSNRGRWGDDDELGTLNHITDEVRLA
                     AARAVRHGRSVSCAWEVAVPGEMERSTTVCPCAADMPGAERMPVPGFRNDRRWGFSNER
                     LGIMFHGNTITHVDSPCHLLWDGRMYNGRPHSLLDAETGSAWAAVTAAANGIVTRGVLL
                     DVAEAREVPWLEPGQGVFPEDLEEAERRQGVRVRPGDAVLLRTGYGRVRHEAGDSGGFT
                     QAGWHASCLPWLHDRGVALIGADTPQDVQPSGYQDVLMPVHAVGLVAMGLWLLDNCDLE
                     ACAATAAELGQWDFQLAVAPVRFAGTSGSPVNPIATF"
     gene            1429..3672
                     /locus_tag="A4R43_RS03200"
                     /old_locus_tag="A4R43_03140"
     CDS             1429..3672
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R43_RS03200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R43_03140"
                     /product="hypothetical protein"
                     /protein_id="WP_113690906.1"
                     /transl_table=11
                     /translation="MKKSTVGKAALVSLSGGVLTVAFGLLGAESAEAAPAPPPPKSDAQ
                     KKADRDRAEQVEAADRNREKAEKKAKEDKKKADRDRNEQVEAADMGRERAEKKAKEDKK
                     KADRDRNEKVEEADLKEQRGEGNAKEAKKKADRDRNEQVEAADMEREDAEKKAKEDKKK
                     ADRDRNEKVEAADLNQQKAEKKSAEDKKKADRARAEKTESDDLTRERAKKEKKKADLAE
                     AERVEAADMGRERAEKKAKEEKKKADRDQAEKVEAADMEREDAEAKAKEDKKKADLAQA
                     ERVEAADMGRERAEKKAKEDKKKADLAQAERVETADMEREDAEAKAKADKKKADLAKAE
                     QIEAADMEREDAEKQAKEAKKQADRARNEAVEAADLGAQRGEVDLAAETKKADLARAEA
                     VEAADLGYERAKDVADEKKARAARDRGDAVEAADLGYERAKDTATAKKQQAVRDRGEQV
                     EAADLGYERAEDSAKAEKKQAVRDRGEAVEAVDLGYERAKDTAKTEKERAVRDRGDAVE
                     AADLGYERAEDTAEAEKKQAQRDRGEAVEAADREFDRAGGYSVDRLRKALPNGSAAPQA
                     APERSPVQRAIEDTHHVASDASRRALDDLQHPIKAGVLGGGAAALETPGAILEQRVLQQ
                     QKNGGIADPDLVRRADEFKLLGKAGGVAGGLAGAYYDIAVEKKDPAKATAANLIGTIAG
                     GAAGGAMAGAVGGPIGIGAGFLFGGAVSALSSGAVEAAWDYFAPPEAVEPPEK"
     gene            3787..4242
                     /locus_tag="A4R43_RS03205"
                     /old_locus_tag="A4R43_03145"
     CDS             3787..4242
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R43_RS03205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R43_03145"
                     /product="hypothetical protein"
                     /protein_id="WP_113690907.1"
                     /transl_table=11
                     /translation="MDGGGRRRLGWVLAALTAAVAVVSTGVVLLVSAPGEPDAGEFAGD
                     VAEVLTQGGDEPFRAVFCESAVERRDGVDVFALVRPITVTVQTVVNESDTHALAVLAID
                     KERDRVFLSMDKQQPGWCVSAIHLCTPAAEPSFDPPRLPCAGLLGRD"
     gene            complement(4154..5542)
                     /locus_tag="A4R43_RS03210"
                     /old_locus_tag="A4R43_03150"
     CDS             complement(4154..5542)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672104.1"
                     /locus_tag="A4R43_RS03210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03150"
                     /product="MFS transporter"
                     /protein_id="WP_113690908.1"
                     /transl_table=11
                     /translation="MTTQLYRWRWPALAALLLAEAMNLLDGTVLPVAGPAIQADLAVDD
                     ATLQWLTAGYTLPFALLLITGGRLGDIFGRRRVFTAGVLSFVVCSAVCAVAPTAAVLLA
                     ARVVQGASAAVLIPQTFGLIRAMFTGTEVAKALGTIGPVMALSSVCGPVAGGLLTDADL
                     FGLGWRPVFLINVPLGLAVLAAAPLIREDRSHARPRLDVGGTLLASTGIGLVVFPLVEG
                     NGTGWTWLCFTLGLVTLAAFAVHQRGRTDPLVEPGLFRGRVFPASLAGSLLFFAVMNGL
                     LFVLVLFLQLSQGKTPTGAALTLLPWSAGLAIGSWAAGSVLVPRFGPKVMRAGLVLVLA
                     GLAGIAVSLTVVPLLVTGIGLGLFTVPFFGNALAGVAAHETGSASGLLNAVQQLGATVG
                     VALLGTVFFRYGTHASVFVALALIAVVLALTLAMISPGRATRHTAGAAGRTTARPPGYT
                     GGSR"
     gene            5635..6597
                     /locus_tag="A4R43_RS03215"
                     /old_locus_tag="A4R43_03155"
     CDS             5635..6597
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637150.1"
                     /locus_tag="A4R43_RS03215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03155"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_113690909.1"
                     /transl_table=11
                     /translation="MTFDELDRAVLHALHVDGRAPFNQIAAVLGTSQQTVARRYRRLRS
                     DGVLRVVGMTDARRLGQVEWFLRLHCTPDSALPVARALARRADTSWVQLTSGGTEISCV
                     IRAPGGNAPEALLLQQLPKTPRVVSVSAHCLLRSFVGGPVGWHGRAGVLTGEQIARLRP
                     DFGPAVSEVDITGDDRLLAALRRDGRATFAELAAATGLSEPTVRRRVNQLRASGILYLD
                     IDLDAAVLGFHAQAILWLSVRPAHLVAAAEALARQPEVALAAITTGPANLLAKVVCRDV
                     DALYACLTERVGTIEAIDRLETAPVIRTLKRAATAKISG"
     misc_feature    complement(6687..6701)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 29.02"
                     /tool="antismash"
     misc_feature    6688..6702
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.15"
                     /tool="antismash"
     misc_feature    6720..6734
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.73"
                     /tool="antismash"
     misc_feature    complement(6745..6758)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.7"
                     /tool="antismash"
     gene            6748..7404
                     /locus_tag="A4R43_RS03220"
                     /old_locus_tag="A4R43_03160"
     CDS             6748..7404
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223308.1"
                     /locus_tag="A4R43_RS03220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03160"
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_113690910.1"
                     /transl_table=11
                     /translation="MRMRSTSRSTLRRRSLFALVGVLAAMIAWVPTASAHGTIVGPPTR
                     AYQCWQKWGSQHTNPEMQQQDPMCWQAFQANADTMWNWMSALRDGLGGNFQGATPDGQL
                     CSNALSRNNSLNNPGAWKTTNVGSNFTMHLYDQASHGADFFRVYVSKNGFDPKTQRLGW
                     GDLDFITQTGRFAPAKDITFNVQTSGYTGHHVVFTIWQASHLDQTYMWCSDVNFG"
     gene            complement(7469..8311)
                     /locus_tag="A4R43_RS03225"
                     /old_locus_tag="A4R43_03165"
     CDS             complement(7469..8311)
                     /NRPS_PKS="Domain: Abhydrolase_1 (24-265). E-value:
                     1.1e-32. Score: 105.5. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03225_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020419882.1"
                     /locus_tag="A4R43_RS03225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03165"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_113690911.1"
                     /sec_met_domain="PF00561 (E-value: 2e-27, bitscore: 95.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.5e-20, bitscore:
                     71.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRSVSVDGARVAVTELGDPAAEPVVLLHGYPANHLSWRHQLAG
                     LAERHRVVAPDLLGWGDSERRLDLRFDYHTEVDRIGMLLDALEIGSCNLFGHDYGGHLA
                     LGFAQRHPDRVRRLAILNSRAHRTFVPQWYAIFSLVGLLGRSPLAGVFARLLPVGMINR
                     VGLRGVLRAGVIDRATLDSYLGWMSTSDGARWVLHFFGDYRVPERRDLADDLSAIRCPA
                     AVIWGTEDAYLRTSIAEELAAGIPGAELTLLDGTGHFVMEEAPDAVLAALQKLLARDA"
     aSDomain        complement(7517..8239)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03225_Abhydrolase_1.1"
                     /evalue="1.10E-32"
                     /label="A4R43_RS03225_Abhydrolase_1.1"
                     /locus_tag="A4R43_RS03225"
                     /protein_end="265"
                     /protein_start="24"
                     /score="105.5"
                     /tool="antismash"
                     /translation="PVVLLHGYPANHLSWRHQLAGLAERHRVVAPDLLGWGDSERRLDL
                     RFDYHTEVDRIGMLLDALEIGSCNLFGHDYGGHLALGFAQRHPDRVRRLAILNSRAHRT
                     FVPQWYAIFSLVGLLGRSPLAGVFARLLPVGMINRVGLRGVLRAGVIDRATLDSYLGWM
                     STSDGARWVLHFFGDYRVPERRDLADDLSAIRCPAAVIWGTEDAYLRTSIAEELAAGIP
                     GAELTLLDGTGHFVMEEAP"
     gene            complement(8308..8724)
                     /locus_tag="A4R43_RS03230"
                     /old_locus_tag="A4R43_03170"
     CDS             complement(8308..8724)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019013.4"
                     /locus_tag="A4R43_RS03230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03170"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_162788298.1"
                     /sec_met_domain="PF07366 (E-value: 2.2e-08, bitscore: 32.9,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPDIVDRFAEAWTKMDPDAFTPLFREDVRLIHPLDRNTRGVVE
                     AREFMARTMSLIPDLRYEVQGWASGSGHVLIWGRLHGTLGGGPIEWPLVDRLRLEDGLI
                     AERTAYFDPLVIIAVLVRRPRAWLPYLRTRLVRR"
     misc_feature    8734..8750
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.32"
                     /tool="antismash"
     misc_feature    complement(8745..8758)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.58"
                     /tool="antismash"
     misc_feature    8746..8759
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.09"
                     /tool="antismash"
     gene            8832..9458
                     /locus_tag="A4R43_RS03235"
                     /old_locus_tag="A4R43_03175"
     CDS             8832..9458
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016333876.1"
                     /locus_tag="A4R43_RS03235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03175"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_113690913.1"
                     /transl_table=11
                     /translation="MATAKGLDPRKQRTIDALLSAAEHTFSRRSVEEVTVEEIAERAGV
                     AVGSIYNNFGSKAGLHAAVVSRALDVDREYMDRAYTPERSPIEQLEAAAEQYLRFYLEQ
                     PQYFRMLAFPAPLGGYPAAAETAARLARRVDEQNARMVDAIERGIADGTIRPLDARKAA
                     TVLWASWNGVVSLAWRPDDLREDERGLAELLALATNIASWGLRNA"
     gene            9660..9794
                     /locus_tag="A4R43_RS44425"
     CDS             9660..9794
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R43_RS44425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_257791789.1"
                     /transl_table=11
                     /translation="MLWASWNGVVSLAWRPDDLREDERGLAELLALATNIASWGLRNA"
     gene            9837..10685
                     /locus_tag="A4R43_RS03245"
                     /old_locus_tag="A4R43_03180"
     CDS             9837..10685
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /locus_tag="A4R43_RS03245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03180"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_162788299.1"
                     /transl_table=11
                     /translation="MTAVREPGGRYLQRRVHRWPGLGLELARWRGGPATEGVCHLPEHL
                     LFVTLGGVTSRTEARIEGGPSYAGADFPGAVTFIPAHRRREARHGDGVLDYVTIRLAPD
                     RMPDGIGENVEFTGFTNGPDPLVRQLALALRAEAAGSGVAGSLFVDSVATTLSLHLLRR
                     HSSLAPRPTAAKPGLTGARLRRVLEHIGDELGGDLRLARLAELAGLEKHQFGRAFKQAT
                     GRTPHQYVLERRVERAAELLTRTELPIAEIAVAVGMSSQSHLTTVFRRLMGETPHAYRR
                     G"
     gene            10755..11804
                     /locus_tag="A4R43_RS03250"
                     /old_locus_tag="A4R43_03185"
     CDS             10755..11804
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012472.4"
                     /locus_tag="A4R43_RS03250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03185"
                     /product="aldo/keto reductase"
                     /protein_id="WP_162788300.1"
                     /transl_table=11
                     /translation="MNASIPSGSTVSRRSMLAATGAGAVVAALGLPGTATAQGGPRPVT
                     RPLGESRVPVIGLGTFMTFDRRPGTDQAFIPAVLRAFHDGGGRVIDTAATYGAAEANTG
                     HHVHALGLTDQVVLTDKSWNCGEYLFDDGHVLAQFARSRQRLHREVIDVVGIHSMTNVG
                     MVLPVLNRLKGEGTIRYVGLTSHEPYQYEGMRPLIEAGAIDVIQIRYSMFQRSAEHGLL
                     SLAADHGVAVMVNMALEKGRLHQVVGSRPVPEFAREAGCESWAQFFLSYVAAHPAVTCV
                     IPATTNPDHVRENLLTMYRPLPDHRQRRRMLRYMEELPEFARIGVTPWYPGKTFPDGLV
                     KLPQPHPVG"
     gene            complement(11773..13215)
                     /locus_tag="A4R43_RS03255"
                     /old_locus_tag="A4R43_03190"
     CDS             complement(11773..13215)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (132-392). E-value:
                     1.4e-10. Score: 32.8. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03255_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020673386.1"
                     /locus_tag="A4R43_RS03255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03190"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_113690916.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.6e-08, bitscore:
                     33.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSGTNSLAAELLVHLDRASKVPLHRQLGTAIRDGVQSGRLPLG
                     TSLPPTRALAADLGVSRGVVVEAYQQLVAEGYLASRSGGYTQVAAGAQTTPRPTPQAVR
                     PATHAIDFGYGRADVSNFPRAAWLRSIRRVLTEIPSDRFGYLDGRGVPELHLALSDYLN
                     RVRGTVATPDRMVICNGFAQGLALLLRVLSAGGARRIAVEDPSADDDTRPIAAELGLSV
                     TGVPVGPDGIDVAVLDRTEADALVLTPSHQWPTGGVLAPDARAAVARWATRTGALVIED
                     DYDTEYRYDRAPIGALQGLAPEQVAYAGTASKTLAPGLRLGWLVLPAHLVGPVAEAKVA
                     ADRGSPVLDQLTFADFLARGEFDRHLRRMRPVYRRRRDALLGALAEFLPDFEPAGILAG
                     LHLVTWLPSDLDEATVVETAARHGIGVAGLAQYHLGTPPRGGLIFGYATLGEQTIRRGV
                     AQLATALGRRGTVSPPDAVAAT"
     aSDomain        complement(12040..12819)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03255_Aminotran_1_2.1"
                     /evalue="1.40E-10"
                     /label="A4R43_RS03255_Aminotran_1_2.1"
                     /locus_tag="A4R43_RS03255"
                     /protein_end="392"
                     /protein_start="132"
                     /score="32.8"
                     /tool="antismash"
                     /translation="RVLTEIPSDRFGYLDGRGVPELHLALSDYLNRVRGTVATPDRMVI
                     CNGFAQGLALLLRVLSAGGARRIAVEDPSADDDTRPIAAELGLSVTGVPVGPDGIDVAV
                     LDRTEADALVLTPSHQWPTGGVLAPDARAAVARWATRTGALVIEDDYDTEYRYDRAPIG
                     ALQGLAPEQVAYAGTASKTLAPGLRLGWLVLPAHLVGPVAEAKVAADRGSPVLDQLTFA
                     DFLARGEFDRHLRRMRPVYRRRRDALLGALAEFLPDFE"
     gene            13262..14578
                     /locus_tag="A4R43_RS03260"
                     /old_locus_tag="A4R43_03195"
     CDS             13262..14578
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020673385.1"
                     /locus_tag="A4R43_RS03260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03195"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_113690917.1"
                     /transl_table=11
                     /translation="MTTTEALRFDGQLLGPGSHGYDQARSVWNAMIDRRPRLIARCASV
                     SDVVRAVHLARERELEIGVRCGGHSGLGLAVPEDGLMIDLTPLSSVRVSGRRAHVGGGA
                     LLGALDRAAQRHGLATTAGNVSHTGVGGLTLGGGMGWLARQYGLACDNVLSYQVVTADG
                     AVVRASATENPELFWGLRGGGGNFGIVTEFEFALHPVGTRALVAEYVFPAERAAAAMRA
                     WRDLSHEAPRRATFTASLGQEGKLEVGFVWVGDPAAAAPLLSQLRELGHPLESRVGELS
                     YLDLQQRDDQTGGHHRRRYSKGHYLPELPDAAIDAFLSRGADDPRQPGLPNAGLQAYGG
                     AIADVAEEDSAFSHRGTKFEYGTGMGWTDPAEDHARMAAARRSARALEPFADGVYVNSL
                     SDDRIQRAYPPAKLARLRALKRTYDPGNVFHLNPNITPA"
     gene            complement(14565..15983)
                     /locus_tag="A4R43_RS03265"
                     /old_locus_tag="A4R43_03200"
     CDS             complement(14565..15983)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155570.1"
                     /locus_tag="A4R43_RS03265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03200"
                     /product="MFS transporter"
                     /protein_id="WP_113690918.1"
                     /transl_table=11
                     /translation="MTTTERTSGSSTAGTALALACVAHFLVVFDTSVITVALPSMRAEL
                     GFTPSGLQWVVNGYTLAFAGLLLFGGRLADIYGHRRVFLGGLAVFTAASLLGGLATTPA
                     MLIAARAGQGAGAAVLAPLAVTLLTTSFPEGPRRTRALTISTAVALVGGAAGNLLGGVF
                     TELLSWRSVLLVNVPIGIPVLFFAARVLARPSDTPWGRVRLDLPGAVLATTGLTLLTFG
                     VSQTHEHNWGHASVALPLVGGLLALIVFVVVEARFAASPLIPPRLFALPGIAWGNLAML
                     LAGASQVPVWFFLTLTMQHVLGYSAAEAGLGFVPHAVVMLVVGLRLVPWLMRRVQARVL
                     IAAGAAIGALGFWWQSRITPDSAYLDGVLGPAVLISIGGGLVGTPLARTVTSGVEPLDA
                     GAASGLMNTTRQFGGAFGLAVLLTVTASGTTGSAATMAGHYGDAFTGIALIMLAIAVLT
                     PVLPATRDGGLRPG"
     gene            complement(15980..16921)
                     /locus_tag="A4R43_RS03270"
                     /old_locus_tag="A4R43_03205"
     CDS             complement(15980..16921)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2OG-FeII_Oxy"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015150.4"
                     /locus_tag="A4R43_RS03270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03205"
                     /product="2OG-Fe(II) oxygenase family protein"
                     /protein_id="WP_113690919.1"
                     /sec_met_domain="2OG-FeII_Oxy (E-value: 7.9e-14, bitscore:
                     50.9, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDATVPTFDLTELRAGRHQDEFRRCLREKGVFYLEGTGLTEADH
                     APAREIAVDFFDHGTEAEKKAVMTPIPTIRRGYAGLESESTAQITNTGKYTDYSMSYSM
                     GTADNLFPSPEFERAWEEYFARMYRASREVARQVLNTAGAEPEGGMDAFLDCEPLLRLR
                     YFPEVPEDRVAEEEPLRMAPHYDLSIVTLIHQTPCANGFVSLQVEVDGSVVDLPARPGA
                     VLVFCGAVATLVADGRIKAPKHHVAAPGAGERVGSSRTSSVFFLRPNGDFRFSVPRARE
                     CGFDVTIPAETATFNDWIGGNYINIRKTAAAR"
     gene            complement(16918..18108)
                     /locus_tag="A4R43_RS03275"
                     /old_locus_tag="A4R43_03210"
     CDS             complement(16918..18108)
                     /NRPS_PKS="Domain: Aminotran_5 (21-387). E-value: 7e-76.
                     Score: 247.4. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03275_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012488.4"
                     /locus_tag="A4R43_RS03275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03210"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_205215229.1"
                     /sec_met_domain="Aminotran_5 (E-value: 8.6e-40, bitscore:
                     135.7, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEKGWAKARDQLCLDPATTDLNAGSCGPLPRPVFDLVTGFRARM
                     AAAPMDFLSRQLPPLLWTARERLAEYLGTRPPRLAFTTNVTGAVNLVASSVALAPGGEI
                     LLTDQEYAPMRWCWERAARRQGLVVRTFRLPVQPLDPEEVVAAATAAMGPRTRLFFFSH
                     VISSTGLVLPAARLCEEARRRGVLTVVDGAQAPGFTGLDLANLPCDYYAGSGHKWLLAP
                     TGVGFLHFTDDQAGVLQPSQVSWGHHPPEGYGPDERTEFGSTPRLRNLECEGTRDLCPW
                     LAVPSAIDFQAGFGHDRIRARTRELAAFTRERLGGWHGLEPVTPPHPELSGAMTSFALP
                     PGTDAGGLQSRLWDRFRIGVAVTGGPGRPLLRVSTHFYNTETDVERLAEALKELSR"
     aSDomain        complement(16948..18045)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03275_Aminotran_5.1"
                     /evalue="7.00E-76"
                     /label="A4R43_RS03275_Aminotran_5.1"
                     /locus_tag="A4R43_RS03275"
                     /protein_end="387"
                     /protein_start="21"
                     /score="247.4"
                     /tool="antismash"
                     /translation="LNAGSCGPLPRPVFDLVTGFRARMAAAPMDFLSRQLPPLLWTARE
                     RLAEYLGTRPPRLAFTTNVTGAVNLVASSVALAPGGEILLTDQEYAPMRWCWERAARRQ
                     GLVVRTFRLPVQPLDPEEVVAAATAAMGPRTRLFFFSHVISSTGLVLPAARLCEEARRR
                     GVLTVVDGAQAPGFTGLDLANLPCDYYAGSGHKWLLAPTGVGFLHFTDDQAGVLQPSQV
                     SWGHHPPEGYGPDERTEFGSTPRLRNLECEGTRDLCPWLAVPSAIDFQAGFGHDRIRAR
                     TRELAAFTRERLGGWHGLEPVTPPHPELSGAMTSFALPPGTDAGGLQSRLWDRFRIGVA
                     VTGGPGRPLLRVSTHFYNTETDVERL"
     misc_feature    complement(17053..17055)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(18332..18347)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.32"
                     /tool="antismash"
     gene            18613..19947
                     /gene="lat"
                     /locus_tag="A4R43_RS03280"
                     /old_locus_tag="A4R43_03215"
     CDS             18613..19947
                     /EC_number="2.6.1.36"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0045484 - L-lysine 6-transaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (33-388). E-value: 9.3e-69.
                     Score: 223.9. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03280_Aminotran_3.1"
                     /codon_start=1
                     /gene="lat"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640593.1"
                     /locus_tag="A4R43_RS03280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03215"
                     /product="L-lysine 6-transaminase"
                     /protein_id="WP_205215230.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.4e-76, bitscore:
                     256.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METPVRAPAAHEVRQVLARHVLTDGYDLVLDLSASSGCWLVDAVT
                     GTRYLDLFSFFASSPLGINPSCIVDDEAFVAELAAAAVNKPSNPDVYTVPYARFVTTFA
                     RVLGDPLLPHLFFVDGGALAVENALKAAFDWKAQKLGLDDAAVNRLQVLHLERSFHGRS
                     GYTLSLTNTEPAKTTRYPKFDWPRIPAPALRHPESVYAEENRRAERQALEAAEAAFRAA
                     DGMIACFLAEPIQGEGGDNHFSAGFLQAMQELCRRHDALFVLDEVQSGCGITGTAWAYQ
                     QLGLRPDLVAFGKKTQVCGVMGGGRIDEVPGNVFAVSSRISSTWGGNLADMVRATRVLE
                     TIERTRLLDTVVQRGKYLRDGLEALAERHPAVLTNARGRGLMCAVDLPGTGHRDEVLRR
                     MYAGHQVIALPCGPRGLRFRPPLTITESEIDRGLEALAASAAPAS"
     aSDomain        18712..19776
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03280_Aminotran_3.1"
                     /evalue="9.30E-69"
                     /label="A4R43_RS03280_Aminotran_3.1"
                     /locus_tag="A4R43_RS03280"
                     /protein_end="388"
                     /protein_start="33"
                     /score="223.9"
                     /tool="antismash"
                     /translation="ASSGCWLVDAVTGTRYLDLFSFFASSPLGINPSCIVDDEAFVAEL
                     AAAAVNKPSNPDVYTVPYARFVTTFARVLGDPLLPHLFFVDGGALAVENALKAAFDWKA
                     QKLGLDDAAVNRLQVLHLERSFHGRSGYTLSLTNTEPAKTTRYPKFDWPRIPAPALRHP
                     ESVYAEENRRAERQALEAAEAAFRAADGMIACFLAEPIQGEGGDNHFSAGFLQAMQELC
                     RRHDALFVLDEVQSGCGITGTAWAYQQLGLRPDLVAFGKKTQVCGVMGGGRIDEVPGNV
                     FAVSSRISSTWGGNLADMVRATRVLETIERTRLLDTVVQRGKYLRDGLEALAERHPAVL
                     TNARGRGLMCAVDLP"
     CDS_motif       19351..19395
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03280_0001"
                     /evalue="2.90E-03"
                     /label="C2_LCL_024-062"
                     /locus_tag="A4R43_RS03280"
                     /protein_end="261"
                     /protein_start="246"
                     /score="10.1"
                     /tool="antismash"
                     /translation="FLQAMQELCRRHDAL"
     gene            20001..30893
                     /locus_tag="A4R43_RS03285"
                     /old_locus_tag="A4R43_03220"
     CDS             20001..30893
                     /NRPS_PKS="Domain: AMP-binding (256-667). E-value: 4.2e-96.
                     Score: 314.0. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03285_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (775-844). E-value: 5.1e-22. Score:
                     69.9. Matches aSDomain: nrpspksdomains_A4R43_RS03285_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (870-1167). E-value:
                     8e-60. Score: 194.4. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03285_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1333-1741). E-value:
                     4.1e-103. Score: 337.0. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03285_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1848-1918). E-value: 7.9e-20.
                     Score: 62.8. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03285_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1932-2225). E-value:
                     2.7e-76. Score: 248.4. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03285_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (2386-2785). E-value:
                     1e-101. Score: 332.4. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03285_AMP-binding.3"
                     /NRPS_PKS="Domain: PCP (2896-2962). E-value: 9e-20. Score:
                     62.7. Matches aSDomain: nrpspksdomains_A4R43_RS03285_PCP.3"
                     /NRPS_PKS="Domain: Epimerization (2981-3260). E-value:
                     1.2e-100. Score: 329.4. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03285_Epimerization.1"
                     /NRPS_PKS="Domain: Thioesterase (3412-3624). E-value:
                     9.2e-43. Score: 139.2. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03285_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF003417.0"
                     /locus_tag="A4R43_RS03285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03220"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_113690921.1"
                     /sec_met_domain="Condensation (E-value: 6.9e-80, bitscore:
                     267.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.8e-15, bitscore:
                     53.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-111, bitscore:
                     370.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 1.9e-24, bitscore:
                     86.1, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSAKHLKTAADWCERIAAIAGQRCDLEMLLKDQWRHRVAVRDDD
                     PAVRASQRQELVFAGQDYTALKEAVDGGASLGAYALATLHSVLHAYGHGHQTVVAFLQH
                     DRVLPVLVDHLAQGGLSCATAVERIDEAVRRPDNYLARPELLQRGLFDALLVLTDRPLT
                     LAELPPSPLVVIVRDDPAARCLRWTLAYAGELFEDKIIAGVLDVAREVLGQFARRPEQL
                     VADLDLVSADQELRLHQWNGTDGEFDEEHRLNELFEDVVRRAPDREAVVCGDLSLTYRE
                     INERANRFAHWLLEVPVRRGDLIGLYLDKSDLGVVATFGIWKAGAAYVPIDPGYPAERI
                     RFIAGDTGLSGIVTNRRHAARLREVLAAEHPSVRVIEIETVLAERQPEAARENPRLELS
                     SQDRAYVTYTSGTTGVPKGVPKYHYSVVNSITDLSERYDMRRAGTERVALFASYVFEPH
                     LRQTLIALLNEQTLVIVPDDVRLDPDRFPSYIERHGVTYLNATGSVLQHFDLRRCPSLR
                     KLLLVGEELTAAGLRQLREKYSGHVVNEYAFTEAAFVTATKEFAPGVTERRDRSIGRPL
                     RNVKWYVLSQDLKQLPIGAIGELYIGGCGVAPGYLNRDDLTAERFTANPFQTEEEKARG
                     RNGRLYRTGDLARVLLNGEVEFMGRADFQLKLNGVRVEPGEIEAQATEFPGVRKCVVVA
                     KETAAGGRHLVGYYVPEESARVAEDELLAFLEQRLIRIMVPARMVPLSSIPVNVNGKVD
                     WRALPDVRIDQPEHAPADGVTGRLREIWSEVLGVPAGRIGDHDDFFRLGGQSILCILLI
                     ARVRQRLGRSLGVEDVFSLRTLGALAGYLEQQAQDAEAASVADEVTTGGAPVRLLANGL
                     QQGLLYHHLKTAGGDDAYVVQSVHHYHAPIRPELMKDAWQHARRKYPALRLRFAWGDDP
                     VQIVDNDDKPVDWRFADLSEVSDAEARIRELQERDRTEPYELAGGRLFRVYLIKQREDL
                     FTLIFSCHHIILDGWSLPVLHDEVHRAYLALCTGAPLESEVDKAYVAAQRYWEAHRDDH
                     TAYWAERIARIDERGDLAGLLNERSRYRVSLADYDHVREHRTRKLCLGAGLTAALKAGC
                     AADQVTLHSVLQFVWHQVLHAIGGGTTTVVGTIVSGRNLPVDGIEHSAGLFINTLPLIV
                     DHREQAGRSVAEAVREIQATVNTMNGKSVVELGRLHSGELKRRLFDTLLVLENYPRLLD
                     EAEERAHQEQLRFEKAYDADKVDYPIAVVAREEGDELTVTLWYAGELFDEDTIDTLLEV
                     ARTLFRQVAEDISRPVRELELVSPEMLARFDSWNETDEEFPADKTLHAVFEEMAARWPD
                     EIAVVYRENRLTYRELNERANRLAHYLRSVAELRPDDLVALMVDKSELMIVAIIAAWKT
                     GAAYVPIDSGYPDDRISFMLADTAARLVVTNEIHSERLRALPGAETRHVLEIELLHLGD
                     QPAENPVTQTTSTDLAYAIYTSGTTGKPKAVLVEHRGVVNLQVSLAKLFGLAKERGDEA
                     LLSFSNYIFDHFVEQMTDALLNGQKLVVLDDTMRTEPERLYRYLNDERVTYLSGTPSVL
                     SLYDYSTATTLTRIDAIGEDFTEPVFGKIRGTFGGLIINGYGPTEVSITSHKRPYPPDV
                     PRVNKSIGFPVANTRCYVLNEAMKRVPVGGIGELYLGGIGVARGYLNREDLTAERFLDN
                     PFQTPEERRRGENGRLYKTGDLVRWLPNGEVEYLGRTDLQVKIRGQRVELGEVEAALSS
                     YPGVVRSLVVAREHTPGQKYLVGFYVGDQEFDEPDLKQWMRRQLPESVVPARVLRITDI
                     PVTPSGKLDTRRLPETDFGAGEGAEYVAPVSECELKLCGIWAQVLGIAPDRIGAHDDFF
                     ALGGDSIRAMALAQAITTGFGQGLGVATVLQHTTLAAQAEHIQAAALEQAWTPLPAAAE
                     HPPVSLAQERLLFIDDFEGGTAAYNIPFALRLPVTDRDVVAGALRTLVGRHPALRTLLK
                     SDGHGVRRQFTVPADQAAPRLEVTTVDSVAKLDEVLVEHAAHVFRLHEELPIRAELVEH
                     GDECYLSVVVHHTCFDGWSWDIFRRELAALLDGVPEAELGSLRGTYAEFAVWQRQYLTG
                     GRLSALTAFWTDALAGFETINLPLDHPRPPRFDYRGRELEFQVDERTTEALRELARTTR
                     VSLYSVLLGAWCVVLNLYTGQHDLVVGTPSANRGRPEFDRTIGFFANLLALRVRVDPAA
                     TVPAYVRSVGEVVVAAQVHGELPFEQLVKELAVEQDPSRHPVLQVNFTVQNVSDHTSAL
                     TEYKPDADGWTTTKFDLSATLTETATGLAGNLTYAASLFEDSSAGGIIATFEHVLAEFA
                     ASAADTPVARLSAVGEPEQDALLRPAAEPPVQRTRTLHAVFEEVAATWPDEIAVVHGAT
                     RLSYRELNERANRLAHHLRSAGGLRPDDLVGLVLDQTELTVVAILAVWKAGAAYVPVDP
                     GYPDDRISFMLADTGAKLVLAGEAHGSRVRGLTAAKVLDLELLDLAGESAENPVTETTG
                     TELAYAIYTSGTTGRPKAVLVSHGSADSFRAQLSGRYFGTPDEQREAVLFLSNYVFDFS
                     VEQLALSVLAGHKLIVPPPSAAGDPEFYALANREGLSYLSGTPTQVQRFDLARLTHLRC
                     VLVAGEAFRPQHFDKIRGEFGGPILNAYGTTETTVYNTVHRFEPGEPHRNTLGAPLGNT
                     RLYVLGDGMKLLPAGAVGELYLGGECVTEGYLHRPELTAERFVPNPFPAEAARYPMLYR
                     TGDVVRRGQDGELRYLGRNDAQVKINGLRIEPGEVEAVLASCPGVRQCAVVAGADPLAP
                     ERTRLVGYYLPEPGTAVNENDLFDALRGRLMPSMVPSLLVRLDRPLPMTITGKLDVAAL
                     PSADFTPKRAAYAAPRDRVEARLCQLWSEHLPGGSAGIDDDYFRSGGDSISALRLAAQV
                     QREFERKISVKHLFDHPTVRQFAANVLSGLEDGPPSGEEAEQGRLTGDCPLLPIQEWFF
                     AKPLPEPHRWNHNFAIRTPALDPGRLRAALDRLTDHHDAFRLRFPEPGKQVYADNAPPV
                     TLHELDVRQADVRQRLIDWQSEFDLAHGPTAVVAYLHGFDDGSARVWFAMHHLVVDTVS
                     WRILAQDLEILYNGGDLGAKSGSYRQWARAVREYAPDDEERRFWAETTRDMEPAEALTR
                     TDSTRRREEFALTAEHTATLLTDSPWAYDTEVNDLLLTATGFALRSITRQATNHVTVEG
                     HGRELFDGAPDVRDTVGWFTTMHPFAVEVDPGDLGRSILTTKANRRRVPHHGIGYGALS
                     GGRAPLPVVSFNYLGRLGTAVTETMEPVEAWHLDPAMSGSHTTDRNRAANPAGIDVTMS
                     CVGGRLTAVVDSLLGEAATRLFASELKVWLERLITHTATRARNEPARATEPFDPYILVN
                     EEAERTLFVLPPGEGGAESYLSNLARQLTDHRLVLFNNVHLHTPMGSFEELGRYYTEHL
                     RRLQPSGPYHLLGWSFGGVLSLEIARRLARAGERIASLLLIDPYFGMRQASASIGLPEV
                     EDILDPINYHYQPDEADLARLADRLGEVVLFQAGELNDVVNGPHQPRLFEFYQRTRHNN
                     LDLLLPAERIEVEVLAGETHHSWVRNEELVKAMCERISTSTGRSS"
     aSDomain        20769..22001
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03285_AMP-binding.1"
                     /evalue="4.20E-96"
                     /label="A4R43_RS03285_AMP-binding.1"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="667"
                     /protein_start="256"
                     /score="314.0"
                     /specificity="substrate consensus: Aad"
                     /tool="antismash"
                     /translation="FEDVVRRAPDREAVVCGDLSLTYREINERANRFAHWLLEVPVRRG
                     DLIGLYLDKSDLGVVATFGIWKAGAAYVPIDPGYPAERIRFIAGDTGLSGIVTNRRHAA
                     RLREVLAAEHPSVRVIEIETVLAERQPEAARENPRLELSSQDRAYVTYTSGTTGVPKGV
                     PKYHYSVVNSITDLSERYDMRRAGTERVALFASYVFEPHLRQTLIALLNEQTLVIVPDD
                     VRLDPDRFPSYIERHGVTYLNATGSVLQHFDLRRCPSLRKLLLVGEELTAAGLRQLREK
                     YSGHVVNEYAFTEAAFVTATKEFAPGVTERRDRSIGRPLRNVKWYVLSQDLKQLPIGAI
                     GELYIGGCGVAPGYLNRDDLTAERFTANPFQTEEEKARGRNGRLYRTGDLARVLLNGEV
                     EFMGRADFQLKL"
     aSModule        20769..22532
                     /complete
                     /domains="nrpspksdomains_A4R43_RS03285_AMP-binding.1"
                     /domains="nrpspksdomains_A4R43_RS03285_PCP.1"
                     /locus_tags="A4R43_RS03285"
                     /monomer_pairings="Aad -> Aad"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20955..20996
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0001"
                     /evalue="2.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="332"
                     /protein_start="318"
                     /score="17.7"
                     /tool="antismash"
                     /translation="FGIWKAGAAYVPID"
     CDS_motif       21210..21260
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0002"
                     /evalue="1.80E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="420"
                     /protein_start="403"
                     /score="20.5"
                     /tool="antismash"
                     /translation="AYVTYTSGTTGVPKGVP"
     CDS_motif       21774..21863
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0003"
                     /evalue="3.50E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="621"
                     /protein_start="591"
                     /score="51.3"
                     /tool="antismash"
                     /translation="PIGAIGELYIGGCGVAPGYLNRDDLTAERF"
     CDS_motif       21969..22034
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0004"
                     /evalue="2.80E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="678"
                     /protein_start="656"
                     /score="29.2"
                     /tool="antismash"
                     /translation="FMGRADFQLKLNGVRVEPGEIE"
     aSDomain        22326..22532
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03285_PCP.1"
                     /evalue="5.10E-22"
                     /label="A4R43_RS03285_PCP.1"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="844"
                     /protein_start="775"
                     /score="69.9"
                     /tool="antismash"
                     /translation="RLREIWSEVLGVPAGRIGDHDDFFRLGGQSILCILLIARVRQRLG
                     RSLGVEDVFSLRTLGALAGYLEQQ"
     CDS_motif       22389..22418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0005"
                     /evalue="5.80E+00"
                     /label="PCP_mE"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="806"
                     /protein_start="796"
                     /score="1.3"
                     /tool="antismash"
                     /translation="DFFRLGGQSI"
     aSDomain        22611..23501
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03285_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="8.00E-60"
                     /label="A4R43_RS03285_Condensation_DCL.1"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1167"
                     /protein_start="870"
                     /score="194.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIILDG"
                     /tool="antismash"
                     /translation="LQQGLLYHHLKTAGGDDAYVVQSVHHYHAPIRPELMKDAWQHARR
                     KYPALRLRFAWGDDPVQIVDNDDKPVDWRFADLSEVSDAEARIRELQERDRTEPYELAG
                     GRLFRVYLIKQREDLFTLIFSCHHIILDGWSLPVLHDEVHRAYLALCTGAPLESEVDKA
                     YVAAQRYWEAHRDDHTAYWAERIARIDERGDLAGLLNERSRYRVSLADYDHVREHRTRK
                     LCLGAGLTAALKAGCAADQVTLHSVLQFVWHQVLHAIGGGTTTVVGTIVSGRNLPVDGI
                     EHSAGLFINTLPLIVD"
     aSModule        22611..25754
                     /complete
                     /domains="nrpspksdomains_A4R43_RS03285_Condensation_DCL.1"
                     /domains="nrpspksdomains_A4R43_RS03285_AMP-binding.2"
                     /domains="nrpspksdomains_A4R43_RS03285_PCP.2"
                     /locus_tags="A4R43_RS03285"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       22659..22775
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0006"
                     /evalue="6.70E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="925"
                     /protein_start="886"
                     /score="12.1"
                     /tool="antismash"
                     /translation="DAYVVQSVHHYHAPIRPELMKDAWQHARRKYPALRLRFA"
     CDS_motif       22986..23051
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0007"
                     /evalue="7.70E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1017"
                     /protein_start="995"
                     /score="28.1"
                     /tool="antismash"
                     /translation="CHHIILDGWSLPVLHDEVHRAY"
     CDS_motif       23301..23324
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0008"
                     /evalue="3.70E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1108"
                     /protein_start="1100"
                     /score="-1.1"
                     /tool="antismash"
                     /translation="AALKAGCA"
     CDS_motif       23406..23492
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0009"
                     /evalue="8.70E-11"
                     /label="C5_DCL_263-294"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1164"
                     /protein_start="1135"
                     /score="34.3"
                     /tool="antismash"
                     /translation="VVGTIVSGRNLPVDGIEHSAGLFINTLPL"
     aSDomain        24000..25223
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03285_AMP-binding.2"
                     /evalue="4.10E-103"
                     /label="A4R43_RS03285_AMP-binding.2"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1741"
                     /protein_start="1333"
                     /score="337.0"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FEEMAARWPDEIAVVYRENRLTYRELNERANRLAHYLRSVAELRP
                     DDLVALMVDKSELMIVAIIAAWKTGAAYVPIDSGYPDDRISFMLADTAARLVVTNEIHS
                     ERLRALPGAETRHVLEIELLHLGDQPAENPVTQTTSTDLAYAIYTSGTTGKPKAVLVEH
                     RGVVNLQVSLAKLFGLAKERGDEALLSFSNYIFDHFVEQMTDALLNGQKLVVLDDTMRT
                     EPERLYRYLNDERVTYLSGTPSVLSLYDYSTATTLTRIDAIGEDFTEPVFGKIRGTFGG
                     LIINGYGPTEVSITSHKRPYPPDVPRVNKSIGFPVANTRCYVLNEAMKRVPVGGIGELY
                     LGGIGVARGYLNREDLTAERFLDNPFQTPEERRRGENGRLYKTGDLVRWLPNGEVEYLG
                     RTDLQVKIR"
     CDS_motif       24192..24230
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0010"
                     /evalue="5.10E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1410"
                     /protein_start="1397"
                     /score="13.5"
                     /tool="antismash"
                     /translation="AAWKTGAAYVPID"
     CDS_motif       24429..24488
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0011"
                     /evalue="1.10E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1496"
                     /protein_start="1476"
                     /score="27.2"
                     /tool="antismash"
                     /translation="AYAIYTSGTTGKPKAVLVEH"
     CDS_motif       24993..25082
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0012"
                     /evalue="4.60E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1694"
                     /protein_start="1664"
                     /score="50.9"
                     /tool="antismash"
                     /translation="PVGGIGELYLGGIGVARGYLNREDLTAERF"
     CDS_motif       25188..25253
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0013"
                     /evalue="1.80E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1751"
                     /protein_start="1729"
                     /score="32.9"
                     /tool="antismash"
                     /translation="YLGRTDLQVKIRGQRVELGEVE"
     CDS_motif       25293..25346
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0014"
                     /evalue="8.10E+00"
                     /label="C5_LCL_267-296"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1782"
                     /protein_start="1764"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="VVAREHTPGQKYLVGFYV"
     aSDomain        25545..25754
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03285_PCP.2"
                     /evalue="7.90E-20"
                     /label="A4R43_RS03285_PCP.2"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1918"
                     /protein_start="1848"
                     /score="62.8"
                     /tool="antismash"
                     /translation="ELKLCGIWAQVLGIAPDRIGAHDDFFALGGDSIRAMALAQAITTG
                     FGQGLGVATVLQHTTLAAQAEHIQA"
     CDS_motif       25614..25643
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0015"
                     /evalue="3.80E-01"
                     /label="PCP_mE"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1881"
                     /protein_start="1871"
                     /score="4.4"
                     /tool="antismash"
                     /translation="DFFALGGDSI"
     aSDomain        25797..26675
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03285_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.70E-76"
                     /label="A4R43_RS03285_Condensation_LCL.1"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="2225"
                     /protein_start="1932"
                     /score="248.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHTCFDG"
                     /tool="antismash"
                     /translation="EHPPVSLAQERLLFIDDFEGGTAAYNIPFALRLPVTDRDVVAGAL
                     RTLVGRHPALRTLLKSDGHGVRRQFTVPADQAAPRLEVTTVDSVAKLDEVLVEHAAHVF
                     RLHEELPIRAELVEHGDECYLSVVVHHTCFDGWSWDIFRRELAALLDGVPEAELGSLRG
                     TYAEFAVWQRQYLTGGRLSALTAFWTDALAGFETINLPLDHPRPPRFDYRGRELEFQVD
                     ERTTEALRELARTTRVSLYSVLLGAWCVVLNLYTGQHDLVVGTPSANRGRPEFDRTIGF
                     FANLLALRVRVD"
     aSModule        25797..29780
                     /complete
                     /domains="nrpspksdomains_A4R43_RS03285_Condensation_LCL.1"
                     /domains="nrpspksdomains_A4R43_RS03285_AMP-binding.3"
                     /domains="nrpspksdomains_A4R43_RS03285_PCP.3"
                     /domains="nrpspksdomains_A4R43_RS03285_Epimerization.1"
                     /locus_tags="A4R43_RS03285"
                     /monomer_pairings="Val -> D-Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       25863..25967
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0016"
                     /evalue="3.80E-08"
                     /label="C2_LCL_024-062"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="1989"
                     /protein_start="1954"
                     /score="25.8"
                     /tool="antismash"
                     /translation="AAYNIPFALRLPVTDRDVVAGALRTLVGRHPALRT"
     CDS_motif       26181..26243
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0017"
                     /evalue="7.60E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="2081"
                     /protein_start="2060"
                     /score="24.9"
                     /tool="antismash"
                     /translation="VHHTCFDGWSWDIFRRELAAL"
     CDS_motif       26289..26324
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0018"
                     /evalue="5.10E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="2108"
                     /protein_start="2096"
                     /score="9.7"
                     /tool="antismash"
                     /translation="YAEFAVWQRQYL"
     CDS_motif       26574..26663
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0019"
                     /evalue="5.60E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="2221"
                     /protein_start="2191"
                     /score="44.4"
                     /tool="antismash"
                     /translation="DLVVGTPSANRGRPEFDRTIGFFANLLALR"
     CDS_motif       26715..26828
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0020"
                     /evalue="3.60E-11"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="2276"
                     /protein_start="2238"
                     /score="35.4"
                     /tool="antismash"
                     /translation="EVVVAAQVHGELPFEQLVKELAVEQDPSRHPVLQVNFT"
     aSDomain        27159..28355
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03285_AMP-binding.3"
                     /evalue="1.00E-101"
                     /label="A4R43_RS03285_AMP-binding.3"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="2785"
                     /protein_start="2386"
                     /score="332.4"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEEVAATWPDEIAVVHGATRLSYRELNERANRLAHHLRSAGGLRP
                     DDLVGLVLDQTELTVVAILAVWKAGAAYVPVDPGYPDDRISFMLADTGAKLVLAGEAHG
                     SRVRGLTAAKVLDLELLDLAGESAENPVTETTGTELAYAIYTSGTTGRPKAVLVSHGSA
                     DSFRAQLSGRYFGTPDEQREAVLFLSNYVFDFSVEQLALSVLAGHKLIVPPPSAAGDPE
                     FYALANREGLSYLSGTPTQVQRFDLARLTHLRCVLVAGEAFRPQHFDKIRGEFGGPILN
                     AYGTTETTVYNTVHRFEPGEPHRNTLGAPLGNTRLYVLGDGMKLLPAGAVGELYLGGEC
                     VTEGYLHRPELTAERFVPNPFPAEAARYPMLYRTGDVVRRGQDGELRYLGRNDAQVKIN
                     "
     CDS_motif       27348..27389
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0021"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="2463"
                     /protein_start="2449"
                     /score="18.3"
                     /tool="antismash"
                     /translation="LAVWKAGAAYVPVD"
     CDS_motif       27579..27638
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0022"
                     /evalue="2.00E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="2546"
                     /protein_start="2526"
                     /score="26.4"
                     /tool="antismash"
                     /translation="AYAIYTSGTTGRPKAVLVSH"
     CDS_motif       28137..28226
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0023"
                     /evalue="5.90E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="2742"
                     /protein_start="2712"
                     /score="47.4"
                     /tool="antismash"
                     /translation="PAGAVGELYLGGECVTEGYLHRPELTAERF"
     CDS_motif       28320..28385
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0024"
                     /evalue="4.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="2795"
                     /protein_start="2773"
                     /score="31.7"
                     /tool="antismash"
                     /translation="YLGRNDAQVKINGLRIEPGEVE"
     aSDomain        28689..28886
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03285_PCP.3"
                     /evalue="9.00E-20"
                     /label="A4R43_RS03285_PCP.3"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="2962"
                     /protein_start="2896"
                     /score="62.7"
                     /tool="antismash"
                     /translation="EARLCQLWSEHLPGGSAGIDDDYFRSGGDSISALRLAAQVQREFE
                     RKISVKHLFDHPTVRQFAANV"
     CDS_motif       28752..28781
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0025"
                     /evalue="5.20E+00"
                     /label="PCP_mE"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="2927"
                     /protein_start="2917"
                     /score="1.4"
                     /tool="antismash"
                     /translation="DYFRSGGDSI"
     aSDomain        28944..29780
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03285_Epimerization.1"
                     /evalue="1.20E-100"
                     /label="A4R43_RS03285_Epimerization.1"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="3260"
                     /protein_start="2981"
                     /score="329.4"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDT"
                     /tool="antismash"
                     /translation="TGDCPLLPIQEWFFAKPLPEPHRWNHNFAIRTPALDPGRLRAALD
                     RLTDHHDAFRLRFPEPGKQVYADNAPPVTLHELDVRQADVRQRLIDWQSEFDLAHGPTA
                     VVAYLHGFDDGSARVWFAMHHLVVDTVSWRILAQDLEILYNGGDLGAKSGSYRQWARAV
                     REYAPDDEERRFWAETTRDMEPAEALTRTDSTRRREEFALTAEHTATLLTDSPWAYDTE
                     VNDLLLTATGFALRSITRQATNHVTVEGHGRELFDGAPDVRDTVGWFTTMHPFAVEV"
     CDS_motif       29043..29120
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0026"
                     /evalue="8.70E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="3040"
                     /protein_start="3014"
                     /score="18.2"
                     /tool="antismash"
                     /translation="ALDPGRLRAALDRLTDHHDAFRLRFP"
     CDS_motif       29298..29363
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0027"
                     /evalue="9.60E-10"
                     /label="NRPS-E2"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="3121"
                     /protein_start="3099"
                     /score="30.7"
                     /tool="antismash"
                     /translation="VWFAMHHLVVDTVSWRILAQDL"
     CDS_motif       29724..29771
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0028"
                     /evalue="3.20E-06"
                     /label="NRPS-E5"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="3257"
                     /protein_start="3241"
                     /score="19.5"
                     /tool="antismash"
                     /translation="DVRDTVGWFTTMHPFA"
     CDS_motif       29814..29867
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0029"
                     /evalue="1.90E-07"
                     /label="NRPS-E6"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="3289"
                     /protein_start="3271"
                     /score="23.4"
                     /tool="antismash"
                     /translation="TKANRRRVPHHGIGYGAL"
     aSDomain        30237..30872
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03285_Thioesterase.1"
                     /evalue="9.20E-43"
                     /label="A4R43_RS03285_Thioesterase.1"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="3624"
                     /protein_start="3412"
                     /score="139.2"
                     /tool="antismash"
                     /translation="RTLFVLPPGEGGAESYLSNLARQLTDHRLVLFNNVHLHTPMGSFE
                     ELGRYYTEHLRRLQPSGPYHLLGWSFGGVLSLEIARRLARAGERIASLLLIDPYFGMRQ
                     ASASIGLPEVEDILDPINYHYQPDEADLARLADRLGEVVLFQAGELNDVVNGPHQPRLF
                     EFYQRTRHNNLDLLLPAERIEVEVLAGETHHSWVRNEELVKAMCERIST"
     CDS_motif       30411..30485
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R43_RS03285_0030"
                     /evalue="4.40E-14"
                     /label="NRPS-te1"
                     /locus_tag="A4R43_RS03285"
                     /protein_end="3495"
                     /protein_start="3470"
                     /score="44.7"
                     /tool="antismash"
                     /translation="QPSGPYHLLGWSFGGVLSLEIARRL"
     gene            30890..31873
                     /locus_tag="A4R43_RS03290"
                     /old_locus_tag="A4R43_03225"
     CDS             30890..31873
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2OG-FeII_Oxy"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025587.4"
                     /locus_tag="A4R43_RS03290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03225"
                     /product="isopenicillin N synthase family oxygenase"
                     /protein_id="WP_205215231.1"
                     /sec_met_domain="2OG-FeII_Oxy (E-value: 4.2e-15, bitscore:
                     55.0, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKMPSAEVPTIDVSPLFGTSAEEKMRVGQEINKACRGSGFFYAAN
                     HGVDVQQLQDVVNEFHRTMTDQEKYDLAINAYNKNNPHVRNGYYMAIKGKKAVESFCYL
                     NPSFSEDHPEIKAGTPMHEVNIWPDEERHPRFRPFCEQYYWTMHRLSKTLMRGFALALG
                     KPEEFFEPELKEQDTLSSVSLIRYPYLEDYPPVKTGPDGMKLSFEDHFDVSMITVLFQT
                     EVQNLQVETVDGWQDLPTSDRHFLVNAGTYLAHLTHDYFPAPLHRVKFVNAERLSLPFF
                     FHAGQHTLIEPFHPDGVPDGERNEAVRYGDYLNHGLHSLIVKNGQT"
     gene            31884..32573
                     /locus_tag="A4R43_RS03295"
                     /old_locus_tag="A4R43_03230"
     CDS             31884..32573
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016850.4"
                     /locus_tag="A4R43_RS03295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03230"
                     /product="CmcI family methyltransferase"
                     /protein_id="WP_113690923.1"
                     /transl_table=11
                     /translation="MTDTFLDLNQFRGLGEDPVYHPPVLADRPRDWPLDRWAEAPRDLG
                     YPDFARYQWRGLRLLKDPDTQAAYHDLLCELRPRTIIELGVYSGGSLVWFRDLADLMGL
                     DCQVLGIDRDLSRCQIPDAEMKNISLREADCADLSTFEQLRDLPHPLVLIDDAHANTFN
                     ILRWSVDHLLVEGDYFIIEDMIPYWHRYCPKLLTEYLAAFRGELTMDMVYANTSAQLDR
                     GVFRRSA"
     gene            32588..33451
                     /locus_tag="A4R43_RS03300"
                     /old_locus_tag="A4R43_03235"
     CDS             32588..33451
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF041278.1"
                     /locus_tag="A4R43_RS03300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03235"
                     /product="CmcJ/NvfI family oxidoreductase"
                     /protein_id="WP_113690924.1"
                     /transl_table=11
                     /translation="MPRVSSPLYYAAPLTPAGRADDWCIDAVTRPPEVLFNFRKVGVET
                     LIEDLREGALRPSLDETGFEKADAESTVDHRDLLDNDETALEAYRKETGELLKALTGAD
                     AVEFFDATLRRQDASGDPAAQSPHQRVHVDQSPRSALARALNRRAPGEFRRFQIINVWR
                     PLLEPVRNFPLALCDFRSLDLVADLVPTRLDFPDWLKDRENYSVRHNPKHRWYHWDSLT
                     PDEALVFKCHDSASRALASVGGETASGELLDVAGLCPHTAFYDHNGPSTGHLRTSLELR
                     ALAFHE"
     gene            33475..34407
                     /locus_tag="A4R43_RS03305"
                     /old_locus_tag="A4R43_03240"
     CDS             33475..34407
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2OG-FeII_Oxy"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015150.4"
                     /locus_tag="A4R43_RS03305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03240"
                     /product="2OG-Fe(II) oxygenase family protein"
                     /protein_id="WP_113690925.1"
                     /sec_met_domain="2OG-FeII_Oxy (E-value: 7.2e-12, bitscore:
                     44.6, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADSTVPVFTMTELREGTRQAEFREWTRRGVFYLTGYGATEQDHR
                     LATDTAMDFFQHGTATEKQAVTTDIPTLRRGYSALEAESTAQVTNTGTYTDYSMSYSMG
                     IGGNLFPSEKFEAVWTHYFDTLYRAAQETARLVLTAPGTYDGEDLDTLLDCDPVLRLRY
                     FPEVPEHRAAEYEPRRMAPHYDLSIITFIHQTPCANGFVSLQAEIDGEMVSLPHIEDAV
                     VVLCGAIAPLVTQGAVPAPNHHVVSPDVSRLKGSDRTSSVFFLRPSTDFTFSVPKARKY
                     GLDVSLDMETATFGDWIGSNYVTMHSVTP"
     gene            34436..35998
                     /gene="cmcH"
                     /locus_tag="A4R43_RS03310"
                     /old_locus_tag="A4R43_03245"
     CDS             34436..35998
                     /EC_number="2.1.3.-"
                     /codon_start=1
                     /gene="cmcH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Carbam_trans_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952499.1"
                     /locus_tag="A4R43_RS03310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03245"
                     /product="3'-hydroxymethylcephem-O-carbamoyltransferase"
                     /protein_id="WP_113690926.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 1.2e-15,
                     bitscore: 56.8, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIVAFKPGHDGAVAAIGDRRLRYSLESEKDSRPRYSPILPTTIL
                     DLAERLDAVPDVVALGGWADLRPNRIAYTGAGYAGIDDPIVSTRRFFGKEVKFFSSTHE
                     RSHIYMALGMAPEDDARERAVLVWEGDVGAFYLVGADQRIRRKIPVMSAPGARYSFLFG
                     LADPTFPDTGAKPRLNDAGKLMALAAFGDAADANPDLTNVVERILKQDSMYPAPKAEYR
                     DSVLYNAGVESPECKTAAALLTERLFETFAEVARQELPAGTPLAISGGCGLNCDWNSMW
                     ARLGHFSSVFVAPCTNDSGSALGTALDALATFTGDPRIDWDVYSGLEFVTDTRPDPGRW
                     RARPLDEVALSAALGAGRVVAWVQGRWEIGPRALGNRSLLAEPFSTATKDRLNEIKQRE
                     GYRPIAPVCRVEDLGTVFHEDFEDPYMLYFRHVRESSGVRAVTHVDGSARVQTVREAGN
                     PQLHRLLSAFAAQRGVGVLCNTSLNFNGEGFINRMSDLVLYCESRGIEDMVVGGTWYQR
                     ADG"
     gene            36011..36526
                     /locus_tag="A4R43_RS03315"
                     /old_locus_tag="A4R43_03250"
     CDS             36011..36526
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R43_RS03315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R43_03250"
                     /product="hypothetical protein"
                     /protein_id="WP_113690927.1"
                     /transl_table=11
                     /translation="MTATAAGPRRLGYLELAARITDVAGLHLAPPARILALELGSRSDR
                     PVLPMDPGTASLFAQLDAASRRPGPVHPAACLRFLTRLEHAVPPEGEVYLLCLAPPPVV
                     RDWVAAHPRFTARRPGGEAHWADEVSQCLGHRGARTLRRRTRELEAGLRRWHHSRRDGA
                     FTWVRAGH"
     gene            36617..37417
                     /locus_tag="A4R43_RS03320"
                     /old_locus_tag="A4R43_03255"
     CDS             36617..37417
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-122). E-value:
                     3.4e-13. Score: 41.7. Matches aSDomain:
                     nrpspksdomains_A4R43_RS03320_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020422628.1"
                     /locus_tag="A4R43_RS03320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03255"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_113690928.1"
                     /sec_met_domain="PF00561 (E-value: 1.9e-09, bitscore: 36.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.1e-15, bitscore:
                     55.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTVTSADGTTIAYDRAGSGPLVVFVPGAFNDRTTCAGVAEQLRD
                     RYTVVCPDRRGRGDSGDAIAPADVAAYDVRREIEDLDAVIAAEGGRAAVFGFSSGGTLA
                     LHAAVAGSPITKLALYEPPFAIGGLAGSAREGLRDKLAALITAGRRGDAVAAMQVEGIG
                     LPPELVDQMRQSPMWPQLEAIAQTVVYDATITRAPNLPTPEMARLDLPVLVLSGAESWP
                     GLGAAARELPAHLAKARHAEVPGGAGHEIPAEATAKLVDAFFRD"
     aSDomain        36677..36982
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R43_RS03320_Abhydrolase_1.1"
                     /evalue="3.40E-13"
                     /label="A4R43_RS03320_Abhydrolase_1.1"
                     /locus_tag="A4R43_RS03320"
                     /protein_end="122"
                     /protein_start="20"
                     /score="41.7"
                     /tool="antismash"
                     /translation="PLVVFVPGAFNDRTTCAGVAEQLRDRYTVVCPDRRGRGDSGDAIA
                     PADVAAYDVRREIEDLDAVIAAEGGRAAVFGFSSGGTLALHAAVAGSPITKLALYEP"
     gene            complement(37422..37883)
                     /locus_tag="A4R43_RS03325"
                     /old_locus_tag="A4R43_03260"
     CDS             complement(37422..37883)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225036.1"
                     /locus_tag="A4R43_RS03325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03260"
                     /product="peroxiredoxin family protein"
                     /protein_id="WP_113690929.1"
                     /transl_table=11
                     /translation="MLKAGSPAPRMVLEDTAGRPVRLSDYQGKHAVLLFFLRSTSCPVC
                     LRHVRDLVNRADELAADDVRVLLAVPEDRERAAAWKAKHRIPFPVLTGDRPHELAGLSR
                     KVFGSLQQSGSLLVDREGVVRHAHGATLPTGSYDKKGIAAAVASLRAAA"
     gene            complement(37898..38431)
                     /locus_tag="A4R43_RS03330"
                     /old_locus_tag="A4R43_03265"
     CDS             complement(37898..38431)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005458433.1"
                     /locus_tag="A4R43_RS03330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03265"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_113697315.1"
                     /transl_table=11
                     /translation="MDRGWASEQLIKAAQGGDLESITAVVHGAHPHVRRFAGQLCASPQ
                     DAEDAAQEALLVLYRKIGSLRATAALASWMFRVVRNECLRRARRLADHHDRTDPVASAE
                     DEVLRRLDAEVVAAAIRELPDVQRRVLIMRDVLGQPGRTVAGALGLSTAAMKSHLHRAR
                     AALRTSLRDTATPS"
     gene            38543..39451
                     /locus_tag="A4R43_RS03335"
                     /old_locus_tag="A4R43_03270"
     CDS             38543..39451
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016777.4"
                     /locus_tag="A4R43_RS03335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03270"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_205215232.1"
                     /transl_table=11
                     /translation="MLVDAHVHVVDFLQDRLTPADFARKLAGAGADRAVICGLPMKKKW
                     PVNEPRKPGYYLDGNAPCQYYSLTDELVASLHAELPPELAGRVAPTLCGFDPTDRLAIE
                     HVELVWSRHDSWRGIGEVMLRHDDLTNLTRGENPCADHLALDPVFDFAAERGVPIAVHH
                     DSSSPGRPGQHEYVDQLATMLRRHPRTTVVWCHGGVSRRVEPKDQGTVVADLLDAHPRL
                     HVDLSWALLDHILDHGRLIPQWRELILARPDRFVCGSDVVGPRSDWAAATARLRQLLDD
                     LPPAEREAVACGNALRLWWRE"
     gene            complement(39456..40304)
                     /locus_tag="A4R43_RS03340"
                     /old_locus_tag="A4R43_03275"
     CDS             complement(39456..40304)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020662173.1"
                     /locus_tag="A4R43_RS03340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03275"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_113690930.1"
                     /transl_table=11
                     /translation="MTDKYRAPSSNPVGVDPNRASIARVYDAALGGKDNYEIDREVLAR
                     VAKVAPEVNDLAWSNRKFLIRACRFLAMRAGIKQFLDCGSGLPTAENTHQVVQRIDPDC
                     RVVYVDNDPVVISHGQALLVENDRTHFADADIFTPSEVLGNEVVREHIDFTEPLALLQV
                     GTLHHYTADNGAELMAEYVDALPSGSYVAIAHFFNPGTDELAHLAERMEDIFIHSPMGS
                     GRFRTADEIRAFFPGLELVPPNPEKPGDLELCDLWWPEGPRPRPLNQVEQCIVGAVGRK
                     P"
     gene            complement(40363..42321)
                     /locus_tag="A4R43_RS03345"
                     /old_locus_tag="A4R43_03280"
     CDS             complement(40363..42321)
                     /EC_number="4.2.1.3"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005457529.1"
                     /locus_tag="A4R43_RS03345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03280"
                     /product="aconitate hydratase"
                     /protein_id="WP_113690931.1"
                     /transl_table=11
                     /translation="MGRNLARKLIEEHLVRGEPEPGAAVELRVDQTLTQDATGTLVMQE
                     LEALGLDRARTEVSVQYVDHNLLQSDEKNAEDHLFLQSACRRFGLWFSKAGNGVSHPTH
                     MQRFGVPGKTLAGSDSHTCAAGSLGMLAIGVGGLEVATAIAGQPLRLRMPEIWGVRLTG
                     ELPPWTSAKDVILEMLRRHGVRGGLNRIVEYHGPGVATLSAMDRHVIANMGAELGATTT
                     VFPADDAVREFLRAEDREDDFRELRADPAAGYDVTDHIELSTVEPLVARPSSPGDVVPV
                     REAAGTPVNQVVIGSSANPGLRDFAIAAAVLRGKQADHEVSLDINPSSRQIFADLTKMG
                     ATAELIAAGARIHQAGCLGCIGMGQAPAAGRNSLRTFPRNFPGRSGTPDDSVWLCSPET
                     AAASALTGVITDPRDLGDAPPVLDLPEKAMVNTRMLVPPLPPEEAAREDLVRGPNISTL
                     PDFPPLPDRVEAPVLLKLGDDVSTDEISPAGARALPYRSNVPKLAEFTFTRLDEDYPAR
                     AREVADTGHIVVGGENYGQGSSREHAAITPRYLGLRAVVAKSFARIHWQNLANFGVLAL
                     EFTEPGDYERIEPGDVLVLDDLPGALHADHPEVTVRNQSKDERYRLRHRLSAEQVDAVL
                     AGGLIPRLARSGTTRGW"
     gene            42365..42646
                     /locus_tag="A4R43_RS03350"
                     /old_locus_tag="A4R43_03285"
     CDS             42365..42646
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005455634.1"
                     /locus_tag="A4R43_RS03350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03285"
                     /product="DUF6343 family protein"
                     /protein_id="WP_113690932.1"
                     /transl_table=11
                     /translation="MNASRRRTRAEYERGLPDYHDPTAGYGGAAPAYSALTLRIVLASA
                     AVVLCVAGAVFFVAQDAVWGAVVLGVVAVVSLVDLGWVVHRKRRGEPG"
     gene            complement(42819..43082)
                     /locus_tag="A4R43_RS43765"
                     /old_locus_tag="A4R43_03290"
     CDS             complement(42819..43082)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R43_RS43765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R43_03290"
                     /product="hypothetical protein"
                     /protein_id="WP_236808752.1"
                     /transl_table=11
                     /translation="MAPCARACACATSRHRSPALPKKVVSRRWTSSANGDGGAHTSASA
                     ASSRGRVLSSTSPHTETRRVVLPSKRLSTVNSGVASMLLLPW"
     misc_feature    43212..43223
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            43292..44185
                     /locus_tag="A4R43_RS03360"
                     /old_locus_tag="A4R43_03295"
     CDS             43292..44185
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223310.1"
                     /locus_tag="A4R43_RS03360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03295"
                     /product="TIGR03619 family F420-dependent LLM class
                     oxidoreductase"
                     /protein_id="WP_113690933.1"
                     /transl_table=11
                     /translation="MRIGFSLPVFGKATATPGGVARYARAAEEAGAASLWVGDRLLSPV
                     APEVAYPGYDTMPEEFSIAQDPFILLAVAAAVTEKVTLGSSTINATQYQPATFARQLTS
                     IDVASNGRLLAGLGIGWSPDEYNAVGVPMAERGKRLDDLLDLLEAWWTKDVVAHQGVGY
                     TIPESHVGLKPVRKPPVYLAGFGERAQRRVAERADGWLPVWSVPEQFPAEALTGGLAKI
                     RAAAEKAGRDPGALGVALRVNAGPGTEPELLAEAVKKIVPALDADHAFVDLTYLTSSVD
                     EHIELTGRLLDLIGKG"
     gene            44377..45150
                     /locus_tag="A4R43_RS03365"
                     /old_locus_tag="A4R43_03300"
     CDS             44377..45150
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020647412.1"
                     /locus_tag="A4R43_RS03365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03300"
                     /product="pectate lyase"
                     /protein_id="WP_236808753.1"
                     /transl_table=11
                     /translation="MRGNGKKLTTLIAGLLVAAGLAWPPATATAAPAWPTPTGQVSVNG
                     TISVPSSGLDGGMRRYCCIGDGGQEEDQDPMFLLAPGATLQNVIIGGPAGDGVHCTGPC
                     TLRNVWWEDVGEDAATFRGSGDPAFLVDGGGARSAGDKVFQHNGGGTLTVQNFQAGDFG
                     TFYRSCGNCSTQYQRDVVFRDITLTRPGNRVAGVNTNYGDTARFSGLTIVGDPDRKMVI
                     CQKYIGNDDGDEPDENGSGPDSTHCRYSASDITYQ"
     gene            complement(45156..45584)
                     /locus_tag="A4R43_RS03370"
                     /old_locus_tag="A4R43_03305"
     CDS             complement(45156..45584)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006240666.1"
                     /locus_tag="A4R43_RS03370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03305"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_113690934.1"
                     /transl_table=11
                     /translation="MWTDPDCPVARAADVVGDRWSLLIVRDAMDGARSFTDFQQRTGIA
                     RNILTDRLRKLTTHGLITQVEAPSGKRRVYTLTDAGKDLFAVIVALRQWGERHAFGPGE
                     PHSLLVDEHGEVVPPVVPVAADGSPLTSDTTSVRKKGV"
     misc_feature    complement(45602..45614)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     misc_feature    complement(45640..45652)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: strong, score: 26.12"
                     /tool="antismash"
     gene            45665..46984
                     /locus_tag="A4R43_RS03375"
                     /old_locus_tag="A4R43_03310"
     CDS             45665..46984
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020673420.1"
                     /locus_tag="A4R43_RS03375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03310"
                     /product="MFS transporter"
                     /protein_id="WP_236809419.1"
                     /transl_table=11
                     /translation="MVVGRGTRLVLAVVCGVAVAGVYAGQPVLEPMGRDLGMPRESVGW
                     FVAAGQLGYLAGLVLLVPLGDLLDRRRLIAAHLALVAAGLAIAATAPAAWVALCGLVVA
                     GGFAVVVQTAVAFAAAISPPGERGRTLGVVTSGVVVGILGARAVTGGLADLWGWRSSYL
                     VLAVLSAVLAVVALVALPTDLRVDRSRYGQVIRTLGGLFNNPIFLTRGLVAFFLFASFG
                     TLWSGMALPLAAAPWQLSEAQIGLFGVAGLAGALGAARAGRWGDAGHTGRVTGIALVLL
                     LGSWLAIGQLGWSLPLLVLGVVVLDFAVQAVHVGNQHVLTTAYPERTSSAIGGYMVFYS
                     LGSAFGAAATTALFDAFGWAGPTVLGALLALGALVTAARGGRSAAGPTRRGSSRSRTRA
                     RRRAGSLGTKGFPPTRSGAAGEPAGSRCARGPGAAPSGPA"
     misc_feature    46352..46354
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            47529..48146
                     /locus_tag="A4R43_RS03380"
                     /old_locus_tag="A4R43_03315"
     CDS             47529..48146
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R43_RS03380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R43_03315"
                     /product="hypothetical protein"
                     /protein_id="WP_113690936.1"
                     /transl_table=11
                     /translation="MISRRWRVPVVIACGVLAAAAVGVTVWLSRDEPFEPGAPGYLDLA
                     CGLHLHQRDLNRAAIEADDAEQQLGYAVSTLFLEVGNRELNTRLQDLSNELKVALDEDN
                     DAAFDQARARADAECGERDAFAPEPGALVEVACGIADVLEPGPGPELLLTSSLISAAAE
                     RDAQYEELDKAAARLVLDPASPLDANHPDAEEIAAFRNQCPA"
     gene            complement(48208..48651)
                     /locus_tag="A4R43_RS03385"
                     /old_locus_tag="A4R43_03320"
     CDS             complement(48208..48651)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005157597.1"
                     /locus_tag="A4R43_RS03385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03320"
                     /product="ester cyclase"
                     /protein_id="WP_113697318.1"
                     /sec_met_domain="PF07366 (E-value: 2.8e-37, bitscore:
                     126.3, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTDQETRNQAVFGRFHDALNTHDLALISKTIDEVVHPDVLFHAP
                     VPTGLSGPDALKQVWEVLLRAFPDIRVTTEDTIAAGDKVVFRNTVTGTHLGDYRGHPPT
                     GKSVSYKEIFIVRFDGDRIAETWGVVDVFGQLRQLGLLPDGLL"
     gene            complement(48663..49163)
                     /locus_tag="A4R43_RS03390"
                     /old_locus_tag="A4R43_03325"
     CDS             complement(48663..49163)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020666110.1"
                     /locus_tag="A4R43_RS03390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03325"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_113690937.1"
                     /transl_table=11
                     /translation="MTSTIEPDELKSRLPDPAELFPELTALSGALVKALGDGPIPRTTI
                     SLVQLRAAQLAGSTYLTVRVTDELRTAGEPERRITAVATWADAPYFTADERIALELVEA
                     VMTPNPSGERVSDELFARASAVYSDEALWTLTVAIGHFSLFVPVALIGKPLPGRPPGQN
                     YRK"
     gene            49298..50179
                     /gene="sigJ"
                     /locus_tag="A4R43_RS03395"
                     /old_locus_tag="A4R43_03330"
     CDS             49298..50179
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="sigJ"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013673331.1"
                     /locus_tag="A4R43_RS03395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R43_03330"
                     /product="RNA polymerase sigma factor SigJ"
                     /protein_id="WP_113690938.1"
                     /transl_table=11
                     /translation="MTTTTDPGLSERHQLVNVAYRLLGSLAEAEDVVQEAYARWYALPA
                     AQRAAIEAPGGWLTKVAARLCLNLLGSARVRRERYVGDWLPEPLPEPGGDPADRVALDE
                     SVTMAFLVVLDSMTPAERVAFVLHDVFRYPFTEVAEILGRSPAACRQLATSARRRVRTA
                     RKPAPAARQAEVVRKFKRAWEAGDIGALVGLLDPGVTAVGDGGGRAGTRRSPVEGAEEL
                     VRYLLAIAERLSALELAECTVNGQPGLLARENGVTVTVYAFDLDGERIRNIWAVRNPEK
                     LRLWNTRRAGAA"
ORIGIN
        1 cttcgacgag cagctgccgc tgggcgcgtt cgaaggcacg ctgtacgagg cggaacggtt
       61 ccaggcggtg gcgggtgatc gcttcgtgtt cgtcagcgac ggcgtctaca acgccatcgg
      121 cccgcagggg cagctgtacg gtgacgccga gctgaccgac gcggtgctga ccaccgccga
      181 cctgcccgcc gcgcacgtgc cgggcgccgt gctcaaggaa ctggccaccc ggcgccgcgg
      241 tgcgcacgcc gaggacgacg ccatggtggt ctgcctggac tggttcggcc ccgcctgacg
      301 gactggaacg agggtcgcga atgaccgccg aacggcagct gcccacacag gacgaggtgc
      361 tcgggtactt cgaaacgctg tccaaccggg gacgctgggg cgacgacgac gaactcggca
      421 cgctgaacca catcaccgac gaggtgcgcc tggcggcggc gcgcgccgtg cgtcacgggc
      481 ggagcgtgtc gtgtgcgtgg gaggtcgccg ttccgggcga aatggagcgg tcgaccacgg
      541 tgtgcccgtg tgccgccgac atgccgggtg ccgaacgcat gcccgtgccg gggttccgca
      601 acgaccgccg ctggggcttt tcgaacgagc ggctcggcat catgttccac ggcaacacga
      661 tcacccatgt cgactcgccg tgccacctgc tctgggacgg ccggatgtac aacgggcggc
      721 cgcactcgtt gctcgacgcg gagaccggat cggcgtgggc ggcggtcacc gcggcggcga
      781 acgggatcgt cacgcgcggg gtgctgctgg acgtcgccga ggcccgcgaa gtgccgtggc
      841 tggagccggg ccagggcgtg tttccggagg atctcgagga agccgagcgc cgtcagggcg
      901 tacgagtgcg cccgggtgac gcggtgctcc tgcggaccgg ttacggccgc gtccggcacg
      961 aggccggtga ttcgggcggc ttcacgcagg cgggctggca cgcgtcctgc ctgccgtggc
     1021 tgcacgatcg cggggtggcg ctgatcggcg cggacacccc gcaggacgtt cagccgtcgg
     1081 gttaccagga cgtgctgatg ccggtgcacg ccgtcggctt ggtcgcgatg ggcctgtggc
     1141 tgctcgacaa ctgcgacctg gaggcgtgcg cggcgacggc cgccgaactc ggccagtggg
     1201 atttccagct cgccgtcgcg ccggtccgct ttgccggtac ctccggcagc ccggtcaatc
     1261 cgatcgccac tttctgaccg gcgaaactcg ctcggctgta ctgcaaatgt attgccgctg
     1321 aaccccctcg cgtcacggtg cggacgtccg tcaacgaagg cgaggaatgg tgctcatgcg
     1381 aattcacgaa acgttcacct tccgttcatt tgaaggaggg gaaacgcggt gaagaaatca
     1441 accgtgggga aggccgcgct cgtttcgctg tccggcggtg tgctgaccgt ggcgttcggc
     1501 ttgctgggcg cggaaagcgc ggaggcggca cccgccccgc cgccgcccaa gtccgacgcg
     1561 cagaagaagg ccgaccggga ccgggcggag caggtggagg ccgccgaccg gaaccgggag
     1621 aaggccgaga agaaggccaa ggaggacaag aagaaggcgg atcgcgaccg caacgagcag
     1681 gtcgaagccg ccgacatggg ccgggagcgg gccgagaaga aggcgaagga ggacaagaag
     1741 aaggctgatc gcgaccgcaa cgagaaggtc gaggaagcgg acctcaagga gcagcggggc
     1801 gagggcaacg ccaaggaagc gaagaagaag gccgaccggg accgcaacga gcaggtcgaa
     1861 gccgctgaca tggagcggga ggacgcggag aagaaggcga aggaggacaa gaagaaggcg
     1921 gatcgcgacc gcaacgagaa agtcgaggcc gccgacctga atcagcagaa ggcggagaag
     1981 aagtccgcgg aggacaagaa gaaagcggat cgtgcccgcg ccgagaaaac cgaatccgac
     2041 gacctgaccc gggagcgggc gaagaaggaa aagaagaagg cggacctcgc ggaggctgag
     2101 cgggtcgagg ccgccgacat gggccgggag cgggccgaga agaaggccaa ggaagaaaag
     2161 aagaaggccg accgcgacca ggcggaaaaa gtggaagccg cggacatgga gcgggaggac
     2221 gcggaggcca aggccaagga ggacaagaag aaggccgatc ttgcccaggc cgagcgggtc
     2281 gaagccgccg acatgggccg ggagcgggcc gagaagaaag ccaaggagga caagaagaaa
     2341 gccgatctcg cccaggccga gcgcgtcgaa accgccgaca tggagcggga ggacgcggag
     2401 gccaaggcca aggccgacaa gaagaaggcc gacctcgcca aggcggagca gatcgaggcc
     2461 gccgacatgg aacgcgagga cgccgaaaag caggccaagg aagcgaagaa gcaggccgac
     2521 cgggcccgca acgaagcggt ggaggccgcc gacctgggcg cccagcgagg tgaggtcgac
     2581 ctcgccgccg aaaccaagaa ggccgatctg gcccgggcgg aggcggtcga ggccgccgat
     2641 ctcgggtacg aacgggccaa ggacgtcgcc gacgagaaga aggcgcgggc cgcgcgtgac
     2701 cggggtgacg ccgtggaggc ggctgacctc gggtatgagc gggcgaagga cacggccacg
     2761 gccaagaaac agcaggccgt ccgggatcgc ggcgagcagg tggaggccgc cgacctcggt
     2821 tacgaacgag ccgaggacag cgccaaggcc gagaaaaagc aggccgtgcg tgaccggggc
     2881 gaagcggtgg aagccgtcga tctcgggtat gagcgggcga aggacaccgc caagaccgag
     2941 aaagaacggg ccgtgcgtga ccggggtgac gccgtggagg cggccgacct cgggtatgag
     3001 cgagccgagg acaccgccga ggccgagaag aagcaggccc agcgggaccg cggtgaggcg
     3061 gtggaggcgg ccgaccgcga attcgaccgg gccggtggtt actccgtcga tcgcctgcgc
     3121 aaggccctgc ccaacgggtc ggccgccccg caggccgcgc ccgagcgcag cccggtacaa
     3181 cgggcgatcg aggacaccca ccacgtggcc agcgacgcgt cccggcgggc gctcgacgac
     3241 ctccagcacc cgatcaaggc gggcgtgctc ggcggtggtg cggcggcgct ggagacaccc
     3301 ggtgcgatcc tcgaacagcg ggtgctccag cagcagaaga acggcggcat cgccgatccc
     3361 gacctggtgc gcagggcgga cgagttcaag ctgctcggca aggcgggcgg tgtcgccggt
     3421 gggctggccg gtgcgtacta cgacatcgcc gtggagaaga aggacccggc gaaggcgacc
     3481 gccgccaatc tgatcggcac catcgcgggt ggtgcggccg gtggcgcgat ggccggggcg
     3541 gtcggcggcc cgatcggcat cggggccgga tttctgttcg gtggtgcggt gagcgccctg
     3601 tccagcggcg cggtcgaagc ggcgtgggac tacttcgccc cgccggaggc cgtggaaccg
     3661 ccggagaagt aacggaaaag cggcccgcca ccggtgagtt ccggtggcgg gccgcccggc
     3721 ccgcgtggtg gccggttgag gtcacgggcc ggggttcgct gtgcgtggtc gtgttgactg
     3781 ctcctcatgg acggtggtgg tcgccggcgg ctcggctggg tgctggccgc gctgacagcg
     3841 gcggtggcgg tggtgtcgac cggcgtggtg ctgctggtca gcgcaccggg tgaaccggat
     3901 gccggggaat tcgccggaga cgtggccgag gtgctcaccc agggcggcga cgagccgttc
     3961 cgggcggtgt tctgcgagtc ggcggtggag cgccgtgacg gggtggacgt gttcgcgctc
     4021 gtccggccga tcacggtgac cgtgcagacc gtcgtgaacg agagcgacac gcatgccctc
     4081 gcggtgctcg ccatcgacaa agagcgagat cgggtgttcc tctcgatgga caagcagcag
     4141 cccggctggt gcgtcagcgc gatccacctg tgtaccccgg cggccgagcc gtcgttcgac
     4201 ccgccgcgcc tgccgtgtgc cgggttgctc ggccgggact gatcatcgcg agggtgagcg
     4261 ccagcacgac cgcgatcagc gcgagcgcca cgaacaccga cgcgtgtgtg ccgtagcgga
     4321 agaagacggt acccagcaag gcgacgccga cggtcgcgcc gagttgctgc accgcgttga
     4381 gcagtccgga cgccgagccc gtctcgtgcg cggccacccc ggccagcgcg ttgccgaaga
     4441 acggcacggt gaacaagccc agcccgatcc cggtgacgag cagcggcacc accgtgagcg
     4501 aaaccgcgat cccggccagg cccgccagca ccagaacgag gcccgcccgc atcaccttcg
     4561 gcccgaaccg tggcacgagc accgaacccg ccgcccacga accgatcgcg agcccggccg
     4621 accacggcag cagcgtcagc gcggcgcccg tcggcgtttt cccttgggag agctgcagga
     4681 acaacacgag cacgaacaag agcccgttca tcaccgcgaa gaacaacagc gagccggcga
     4741 gggaggcggg gaaaaccctg ccccggaaca accctggctc gaccagcgga tcggttcgcc
     4801 cgcgctggtg gacggcgaac gcggccagcg tcaccagacc gagcgtgaag cacagccacg
     4861 tccacccggt gccgtttcct tccaccagcg ggaaaaccac cagtccgatc ccggtcgacg
     4921 ccagcagcgt gccgccgacg tccagccgcg gccgggcgtg ggagcggtcc tcgcggatca
     4981 gcggtgcggc ggccagcacg gccaggccca gcggcacgtt gatcaagaac accgggcgcc
     5041 agccgagccc gaacaggtcc gcgtcggtga gcaggccacc ggcgaccggc ccgcacaccg
     5101 acgacaacgc catgaccggg ccgatcgtgc ccagcgcctt ggccacctcg gtgccggtga
     5161 acatggcgcg gatcaggccg aaggtctgcg ggatgagcac ggcggcgctc gcgccctgca
     5221 caacccgcgc ggcgagcagc accgcggcgg tcggcgcgac cgcgcacacc gcggagcaca
     5281 ccacgaagga gagcactccg gcggtgaaca cgcgcctgcg gccgaaaatg tcgccgaggc
     5341 ggccgccggt gatgagcagc agcgcgaacg ggagcgtgta gccggcggtc agccactgca
     5401 gggtggcgtc gtccaccgcg aggtcggcct ggatcgcggg gcccgccacc ggcagcaccg
     5461 tgccgtcgag caggttcatc gcctcggcga gcagcagggc ggcgagcgcc ggccaccgcc
     5521 agcggtagag ctgggttgtc atgtccgcga agctaggtac tggtgactgt cacaacgccg
     5581 tgttgcggcg gatgtgacgg atagttccat cgcggcgggt ttaggatcgg gaatatgacg
     5641 ttcgacgagc tggaccgcgc ggtgctgcac gccctgcacg tcgacggccg cgccccgttc
     5701 aaccagatcg cggcggtgct cggcacctcc cagcagaccg tggccaggag ataccgcagg
     5761 ctgcggtcgg atggtgtgct gcgggtggtc ggcatgaccg acgcccgtcg cctgggtcag
     5821 gtggagtggt tcctgcggct gcactgcacc ccggattcgg cgctgccggt ggccagggcg
     5881 ctggcgcggc gggcggacac ctcgtgggtg cagctcacct cgggcggcac cgagatctcc
     5941 tgcgtcatcc gcgcaccggg cggcaacgcg ccggaagcct tgctgttgca gcaactcccg
     6001 aagacacctc gcgtggtttc ggtgtccgcg cactgcttgc tgcggtcgtt cgtcggcggt
     6061 ccggtcggct ggcacggtcg cgcgggcgtg ctcaccggcg agcagatcgc ccgcctgcgc
     6121 ccggacttcg ggcctgcggt gtccgaagtg gacataactg gggacgaccg gctgctggcc
     6181 gcgctgcggc gggacggccg cgccaccttc gccgaactcg ccgcggcgac cgggttgtcc
     6241 gagccgaccg tgcgccgccg ggtgaaccag ttgcgggcca gcggaatcct ctacctggac
     6301 atcgacctgg acgccgccgt gctgggcttc cacgcccagg cgatcctgtg gttgtccgtg
     6361 cggccggcgc acctggtggc ggccgcggaa gcgctggcgc ggcaaccgga agtcgcgctc
     6421 gcggcgatca ccaccggacc ggcgaacctg ctcgcgaagg tggtctgccg cgacgtcgac
     6481 gcgctctacg cctgcctgac cgagcgcgtc ggcaccatcg aggcgatcga ccgcctggag
     6541 acggccccgg tgatccgcac cctgaagcgc gcggcgacag cgaaaatttc gggctagccg
     6601 accaggccgt cgccggtacg gaggttcgac caccgggcga tgcttggttg aagtttcacc
     6661 gggtggggta taagctcgtg aaccggctgg gagcgctccc aaatggatca ccaccggttc
     6721 actcattccg agaatggagg cccatccatg cgtatgcgca gcacctccag gtccaccctc
     6781 agacggcgca gcctgttcgc gctggtcggc gtgctggcgg cgatgatcgc ctgggtgccg
     6841 acggcttcgg cgcacggcac catcgtcggt ccgcccaccc gcgcctacca gtgctggcag
     6901 aagtggggca gccagcacac caatcccgag atgcagcagc aggatcccat gtgctggcag
     6961 gctttccagg ccaacgccga caccatgtgg aactggatga gcgcgctgcg ggacggcctc
     7021 ggcggcaact tccagggcgc gacgcccgac gggcagctgt gcagcaacgc cctctcgcgc
     7081 aacaactcgc tgaacaaccc cggcgcgtgg aagaccacca acgtcggcag caacttcacc
     7141 atgcacctgt acgaccaggc cagccacggt gccgacttct tccgggtcta cgtcagcaag
     7201 aacggcttcg acccgaagac gcaacgcctc ggctggggcg atctcgactt catcacgcaa
     7261 accggcaggt tcgctccggc caaggacatc acgttcaacg tccagacctc cggctacacc
     7321 ggacaccacg tcgtgttcac catctggcag gcttcccacc tcgaccagac ctacatgtgg
     7381 tgcagcgacg tcaacttcgg ctagggatcg tgctgacgaa cttccggtcc ggtgctgtca
     7441 aacggcaccg gaccggaggt gcgcgggcct aagcgtcgcg tgcgagtagc ttttgcagcg
     7501 cggcgagcac ggcgtccggc gcttcctcca tgacaaagtg cccggtgccg tcgagcagcg
     7561 tgagttcggc gcccgggatg cccgcggcga gttcctcggc gatggacgtg cgcaggtacg
     7621 cgtcctcggt gccccagatg accgcggcag ggcaccggat cgcgctcagg tcgtcggcga
     7681 ggtcccgccg ttcgggcacc cggtagtcgc cgaagaagtg cagcacccag cgtgcaccgt
     7741 ccgaagtgga catccaaccc aggtagctgt cgagggtcgc acgatcgatc accccggccc
     7801 gcagcacacc gcgcaggccg acgcggttga tcatcccgac cggcagcaac cgggcgaaca
     7861 ccccggccag cgggctccgg ccgagcaggc ccaccagcga gaagatcgca taccactgcg
     7921 gcacaaaagt ccggtgcgcg cggctgttga gaatcgccag ccgccggacg cggtcggggt
     7981 ggcgctgggc gaaaccgagg gcgaggtggc cgccgtaatc gtgcccgaac aggttgcaac
     8041 tgccgatttc gagcgcgtcg agcagcatgc cgatgcggtc cacctcggtg tggtagtcga
     8101 accgcaggtc caggcggcgt tccgaatcgc cccagccgag caggtccggc gcgacgacgc
     8161 ggtgccgttc ggcgaggccc gccagctggt ggcgccacga aaggtggttg gcgggatagc
     8221 cgtgcagcag caccacgggc tcggcggcgg gatcaccgag ttcggtgacc gcgacccggg
     8281 ccccgtcgac gctgaccgag cgcgtgctca tcggcggacc agccgggtgc ggaggtaggg
     8341 cagccaggcg cggggtcgcc gtaccagcac cgcgatgatc accagcgggt cgaagtacgc
     8401 ggtccgctcg gcgatcagcc cgtcttcgag ccggagccgg tcgaccagcg gccattcgat
     8461 cgggccgccg ccgagcgtgc cgtgcaaccg cccccagatc agcacgtggc ccgacccgct
     8521 cgcccagccc tgcacctcgt accgcagatc cgggatcagc gacatggtcc tggccatgaa
     8581 ctcgcgtgct tccaccaccc cgcgggtgtt gcggtcgagc gggtggatca ggcgcacgtc
     8641 ctcgcggaac agcggcgtga acgcgtcggg gtccattttg gtccacgctt cggcgaaccg
     8701 gtcgacgatg tcgggcgcgg tcacccggct cacctccgca agtcttgcaa tcattacaac
     8761 aagtggcgcc caagctagca ccgccggaga gaacttgcaa cggctgcaga aaccggccct
     8821 acgatggcgg catggccacc gcgaaggggc tcgacccccg caagcaacgg acgatcgacg
     8881 ccctgctcag cgcggccgag cacaccttct cgcggcggtc cgtggaggag gtgacggtcg
     8941 aggagatcgc cgagcgcgcg ggcgtcgcgg tgggctcgat ctacaacaac ttcgggtcga
     9001 aggcggggct gcacgccgcc gtcgtcagcc gcgcgctcga cgtcgatcgt gagtacatgg
     9061 accgcgccta caccccggag cggtcgccga tcgagcagct cgaagccgcc gccgagcagt
     9121 acctgcggtt ctacctcgaa cagccgcagt acttccggat gctcgccttc ccggcgccac
     9181 tcggcggtta tccggcggcc gccgaaaccg ccgcgcggct cgcccgccgg gtcgacgagc
     9241 agaacgcgcg gatggtcgac gcgatcgaac gcggcatcgc cgacggcacg atccgcccgc
     9301 tggacgcgcg aaaggcggcg acggtgctgt gggcgagttg gaacggtgtg gtcagcttgg
     9361 cgtggcggcc ggacgatctg cgggaggacg agcgtggcct ggctgagctg ctggcgctgg
     9421 cgacgaacat cgcgagctgg ggcctgcgga acgcctgacc cggttccacc tccgctcgaa
     9481 aggcggcgac ggtgctgtgg gcgagttgga atggtgtggt cagcttggcg tggcggccgg
     9541 acgatctgcg ggaggacgag cgtggcctcg ctgagctgct ggcgctggcc acgaacatcg
     9601 cgagctgggg cctgcggaac gcctgacccg gttccacctc cgctcgaaag gcggcgacgg
     9661 tgctgtgggc gagttggaac ggtgtggtca gcttggcgtg gcggccggac gatctgcggg
     9721 aggacgagcg tggcctggct gagctgctgg cgctggcgac gaacatcgcg agctggggcc
     9781 tgcggaacgc ctgaccttca ccggttccac acccaggcgg ccacagactt ggccgcgtga
     9841 cagcggttcg ggagccgggc ggccggtacc tccagcgccg ggtgcaccgg tggccggggc
     9901 tcgggctgga gttggcgcgc tggcgcggcg gcccggccac cgagggcgtc tgccacctgc
     9961 cggagcacct gctcttcgtc accctcggcg gtgtcaccag ccgcacggag gcgcggatcg
    10021 agggcgggcc gtcctacgcc ggggcggact ttcccggcgc ggtcaccttc atcccggcgc
    10081 accggcggcg cgaagcccgg cacggtgacg gcgtgctcga ctacgtgacc atccggctcg
    10141 caccggaccg gatgcccgac gggatcgggg aaaacgtgga gttcaccggg ttcaccaacg
    10201 gcccggaccc actggtccgc cagctcgcgc tcgcgttgcg cgccgaggcc gcgggcagcg
    10261 gcgtggccgg ttcgctgttc gtcgacagcg tcgccaccac gttgagcctg cacctgctgc
    10321 gcaggcattc cagcctcgcg ccccgcccga ccgcggcgaa accggggctg accggcgcgc
    10381 ggttgcggcg ggtgctggag cacatcgggg acgaactcgg cggtgacctg cggctcgcgc
    10441 ggctcgccga gctggcgggg ctggagaagc accagttcgg gcgggcgttc aagcaggcga
    10501 ccggccggac cccgcaccag tacgtgctgg aacgccgcgt cgagcgcgcc gccgaactgc
    10561 tcacccggac cgagctgccg atcgcggaga tcgccgtcgc cgtcggcatg tccagccaga
    10621 gccacctgac cacggtgttc cgcaggctga tgggcgaaac cccgcacgcc taccggcgcg
    10681 gctgaccacg cgaatccgca acgccgcggc gaatgtggaa gacgcccggc gccgcggccg
    10741 gtgaggctga cgccatgaac gcaagcattc cttccggcag cacggtttcc cgtcgttcga
    10801 tgctcgccgc gacgggagcc ggtgcggtgg tcgccgcgct cgggctcccg ggcaccgcca
    10861 ccgcgcaggg cggtccgcgg ccggtcaccc ggccgctcgg ggagtcgcgg gtgccggtca
    10921 tcggcctggg caccttcatg accttcgacc ggcggcccgg caccgaccag gccttcattc
    10981 ccgccgtgct ccgcgccttc cacgacggcg gcggccgggt gatcgacacc gcggccacct
    11041 acggcgccgc cgaggccaac accggccacc acgtgcacgc gctcgggctc accgaccagg
    11101 tggtgctcac cgacaagagc tggaactgcg gtgagtacct gttcgacgac gggcacgtgc
    11161 tggcgcagtt cgcccggtcg cggcagcggc tgcaccgcga ggtgatcgac gtggtcggga
    11221 tccacagcat gaccaacgtc ggcatggtgc tgccggtgct gaaccggctc aagggcgagg
    11281 gcacgatccg ttatgtgggc ctgacttccc acgagccgta ccagtacgag ggcatgcggc
    11341 cgctgatcga ggccggcgcg atcgacgtca tccagatccg gtactcgatg ttccagcggt
    11401 ccgccgagca cggcctgctc tcgctcgccg cggaccacgg ggtcgcggtc atggtgaaca
    11461 tggcgctgga aaagggacgc ctgcaccagg tcgtcggctc gcgtccggtg ccggagttcg
    11521 ccagggaggc cggatgcgag tcgtgggcgc agttcttcct gtcctatgtg gccgctcacc
    11581 cggcggtcac ctgcgtaatt ccggcgacga cgaatccgga ccacgtaagg gaaaacctgc
    11641 tgaccatgta ccgcccgcta ccggatcacc gccagcgtcg ccggatgctg cggtatatgg
    11701 aggaactgcc cgagttcgcc cgcatcggcg tgactccttg gtacccgggc aaaacctttc
    11761 ccgacggcct ggtcaagttg ccgcaaccgc atccggtggg ctgaccgtcc cgcgtcggcc
    11821 gagggcggtg gcgagctggg cgacaccgcg gcggatagtc tgttcgccca gggtggcgta
    11881 gccgaagatc agaccacccc gcggtggcgt cccgaggtgg tactgcgcga gcccggcgac
    11941 accgatgccg tggcgcgcgg cggtttcgac cacggttgct tcgtccaaat cggacggtag
    12001 ccaggtcacc aggtgcagcc cggccaggat gccggccggt tcgaagtcgg gcaggaactc
    12061 cgccagcgcg ccgagcagcg cgtcgcggcg gcgccggtag accgggcgca tgcgccgcag
    12121 gtggcggtcg aactcaccac gggcgaggaa gtcggcgaag gtcagctggt ccagcaccgg
    12181 cgagccccgg tcggcggcca ccttcgcctc ggcaaccggc ccgaccaggt gcgcgggcag
    12241 cacgagccag cccagccgca accccggcgc gagcgttttg ctcgcggtgc ccgcgtacgc
    12301 gacctgctcg ggcgccagcc cctggagtgc gccgatcggc gcgcggtcgt agcggtactc
    12361 ggtgtcgtag tcgtcttcga tcaccagcgc gccggtccgc gtggcccagc gcgccaccgc
    12421 cgcgcgtgcg tccggggcca gcaccccgcc ggtcggccac tggtgcgacg gggtgagcac
    12481 gagtgcgtcg gcttcggtgc ggtcgagcac ggcgacgtcg atgccgtccg ggccgaccgg
    12541 caccccggtg accgacagcc ccagctccgc ggcgatcggc cgggtgtcgt cgtcggccga
    12601 cgggtcctcc accgcgatcc gcctggcgcc cccggcggag agcacccgca gcagcagcgc
    12661 gagcccctgg gcgaacccgt tgcagatgac catgcggtcc ggcgtggcca ccgtgccgcg
    12721 cacgcggttg aggtagtcgc tcagcgccag gtgcagttcc gggaccccgc gcccgtcgag
    12781 gtaaccgaag cggtccgacg ggatttcggt gagcacccgg cggatcgagc gcagccaggc
    12841 cgcgcgcggg aagttcgaca cgtcggcgcg gccgtaaccg aagtcgatcg cgtgagtcgc
    12901 gggccgcacg gcctgcgggg tggggcgcgg cgtggtctgc gcgcccgcgg cgacctgcgt
    12961 gtacccgccg gaccggctgg ccaggtaacc ctcggccacc agctgctggt acgcctcgac
    13021 caccactccc cgcgacacgc cgaggtcggc ggccagcgcg cgggtgggcg gcagcgacgt
    13081 gccgagcggg agccgcccgg actgcacgcc gtcccggatg gcggtgccca gctgccggtg
    13141 cagcggtacc ttcgaagcgc ggtcgaggtg gaccagcagc tcggccgcga gcgaattggt
    13201 ccccgatcgc gtcatggaat tggactttag accgcggacc gattcccgtc acgctttggc
    13261 catgaccact accgaagcac tccggttcga cggacagctc ctcggccccg gcagccacgg
    13321 ctacgaccag gcccgctcgg tctggaacgc gatgatcgac cgccgtccgc gcctgatcgc
    13381 ccgctgcgcc agcgtctccg acgtggtgcg tgccgtgcac ctggcgcgtg aacgggagct
    13441 cgagatcggc gtccgctgcg gcgggcacag cgggctgggc ctggcggtgc ccgaggacgg
    13501 cctgatgatc gacctgaccc cgctgagttc cgtgcgcgtc agcgggcgcc gggcccacgt
    13561 cggcggcggc gcgctgctcg gcgcgctcga ccgcgcggcg cagcggcacg gcctggcgac
    13621 cacggccggc aacgtgtccc acaccggcgt cggcgggctc accctcggcg gcggtatggg
    13681 ctggctcgcc aggcagtacg gcctggcctg cgacaacgtg ctctcctacc aggtcgtcac
    13741 cgccgacggc gcggtcgtac gggcgagcgc caccgagaat cccgagctgt tctggggcct
    13801 gcgcgggggt ggcggcaatt tcggcatcgt caccgaattc gagttcgcgc tgcacccggt
    13861 gggcacgcgg gcgctggtcg ccgagtacgt gttccccgcc gaacgggccg ccgcggccat
    13921 gcgggcctgg cgcgacctga gccacgaggc gccccggcgc gcgaccttca ccgcgtcact
    13981 ggggcaggag ggcaagctcg aagtgggctt tgtctgggtg ggcgacccgg ccgccgcggc
    14041 gccgctgctg agccaactgc gtgaactggg ccacccgctg gaaagccgcg tcggtgagct
    14101 gtcctatttg gacctccagc agcgggacga ccagaccggc gggcaccatc ggcgccgcta
    14161 ctccaagggc cactacctgc ccgaactgcc ggacgccgcg atcgacgcct tcctctcccg
    14221 cggcgcggac gacccgcggc agcccggcct gcccaacgcc gggttgcagg cctacggcgg
    14281 tgcgatcgcc gacgtggccg aggaggacag cgcgttcagc catcgcggca cgaagttcga
    14341 gtacggcacg ggcatgggct ggaccgaccc ggcggaggac cacgcgcgga tggccgccgc
    14401 ccggcggagc gcccgcgccc tcgagccgtt cgcggacggc gtgtacgtca actccctcag
    14461 cgacgaccgg atccagcgtg cctacccgcc ggccaagctc gcccggctcc gcgcgctcaa
    14521 gcggacctac gacccgggca acgtcttcca cctcaacccg aacatcaccc cggcctgagc
    14581 ccgccgtccc gggtggcggg caggaccggg gtgagcacgg cgatggcgag catgatcaac
    14641 gcgatgccgg tgaacgcgtc accgtagtgc ccggccatgg tcgcggcact gccggtggtg
    14701 ccgctcgcgg tcaccgtcag cagcacggcc agcccgaacg cgccgccgaa ctggcgggtg
    14761 gtgttcatca gcccggaggc cgcgcccgcg tcgagcggct cgacaccgga ggtgacggtt
    14821 ctcgccagcg gggtgcccac cagcccgccg ccgatggaga tcagcacggc cggtccgagc
    14881 acaccgtcga gataggcgct gtccggcgtg atccggctct gccaccagaa cccgagcgcg
    14941 ccgatggcgg caccggcggc gatcagcacc cgcgcctgca cccgccgcat cagccacggc
    15001 accagccgca ggccgaccac cagcatcacc accgcgtgcg gcacgaaccc cagccccgct
    15061 tccgcggcgc tgtaacccag cacgtgctgc atggtcaggg tgaggaagaa ccacaccggc
    15121 acctggctcg ccccggccag cagcatggcc aggttgcccc aggcgatccc gggcagcgcg
    15181 aacaggcgcg gtgggatcag cggtgaggcc gcgaacctgg cttcgaccac gacaaatacg
    15241 atcagcgcga gcagtccgcc gaccagcggc agcgccaccg acgcgtggcc ccagttgtgc
    15301 tcgtgggtct gcgaaacgcc gaaggtgagc agcgtcagcc cggtcgtggc cagtaccgcg
    15361 cccggcaggt ccagccgcac ccggccccac ggcgtgtccg atggccgggc gagcacccgc
    15421 gcggcgaaga acagcaccgg gatgccgatc ggcacgttga ccagcagcac cgaccgccac
    15481 gacagcagct cggtgaacac cccgccgagc aggttgcccg cggcgccgcc gaccagcgcc
    15541 accgcggtgg aaatggtcag cgcgcgcgtc cggcgtggtc cctcggggaa cgacgtggtg
    15601 agcagggtga ccgccagcgg cgccagcacg gccgcaccgg cgccctgccc ggcccgcgcc
    15661 gcgatcagca tcgccggggt ggtggcgagc ccgccgagca ggctggccgc ggtgaacacg
    15721 gcgagcccgc cgaggaacac ccgccggtgg ccgtagatgt cggcgagcct gccgccgaac
    15781 agcaggagcc cggcgaaggc cagcgtgtac ccgttgacca cccactgcag gcccgacggc
    15841 gtgaagccca gctccgcgcg catcgacggc agcgccacgg tgatcaccga ggtgtcgaac
    15901 accaccagga agtgcgcgac gcaggccagt gccagcgcgg taccggcagt gctgctcccg
    15961 ctggtccgtt ccgtggtggt caccgcgcgg cggcggtctt ccggatgttg atgtagttgc
    16021 cgccgatcca gtcgttgaag gtggccgtct cggcgggaat ggtgacgtcg aacccgcact
    16081 ccctggccct gggcacggag aaccggaaat ccccgttggg gcgcaggaag aacacgctgg
    16141 aggtgcggct gctgcccacc cgctcgcccg cgcccggcgc ggccacgtgg tgcttgggcg
    16201 ccttgatccg gccgtcggcc accagcgtgg ccaccgcgcc gcagaagacc agcaccgcgc
    16261 ccgggcgcgc cggcaggtcc acaacggacc cgtcgacttc gacctggagg ctgacgaacc
    16321 cgttcgcgca cggggtctgg tggatcaggg tgacgatcga gaggtcgtag tgcggtgcca
    16381 tccgcagcgg ctcctcctcg gccacgcggt cttcggggac ctcggggaag taccgcagcc
    16441 ggagcagcgg ctcgcagtcg aggaaggcgt ccatgccgcc ctccggttcc gcgcccgcgg
    16501 tgttcagcac ctgcctcgcg acctcccgcg aagcccggta catccgggcg aagtactcct
    16561 cccacgcccg ctcgaactcc ggcgacggga acaggttgtc cgcggtgccc atcgagtacg
    16621 acatcgagta gtcggtgtac ttgccggtgt tggtgatctg cgcggtgctc tccgactcca
    16681 gcccggcgta cccgcgccgg atggtcggaa tcggggtcat caccgccttc ttctcggctt
    16741 cggtgccgtg gtcgaagaag tccaccgcga tctcgcgcgc cggggcgtgg tcggcctcgg
    16801 tgagcccggt gccctcgagg tagaagaccc ccttttcgcg gaggcagcgg cggaactcgt
    16861 cctggtgccg tcccgcgcgc agctcggtca ggtcgaaggt gggtacggtc gcgtccgtca
    16921 tctgctcagc tccttcagcg cctccgccag gcgctcgacg tcggtttcgg tgttgtagaa
    16981 gtgcgtggag acacgcagca gcgggcggcc ggggccgccg gtcaccgcca cgccgatgcg
    17041 gaagcgatcc cataaccggc tctgcagccc acccgcgtcc gtgcccggtg gcagcgcgaa
    17101 ggaggtcatc gcgccggaca gctccgggtg cggtggtgtc accggttcca gtccgtgcca
    17161 gccaccgagg cgctcgcggg tgaacgccgc cagctcgcgc gtgcgtgccc ggatgcggtc
    17221 gtggccgaac ccggcctgga agtcgatcgc ggacggcacc gcgagccacg ggcacaggtc
    17281 acgcgtgccc tcgcactcca ggttgcgcag gcgtggcgtg ctgccgaatt cggtgcgctc
    17341 gtccggcccg tacccttccg gcgggtggtg gccccagctg acctgcgacg gctggagcac
    17401 gcccgcctgg tcgtcggtga agtgcaggaa accgaccccg gtgggggcca gcagccactt
    17461 gtgcccgctg cccgcgtagt agtcgcacgg caggttcgcc aggtccagtc cggtgaaccc
    17521 gggtgcctgg gcaccgtcga ccacggtgag cacaccgcgg cggcgggcct cctcgcacag
    17581 gcgcgcggcg ggcaggacca ggccggtcga agagatcacg tggctgaaga agaacagccg
    17641 ggtgcgcggg cccatcgcgg cggtggccgc cgccaccacc tcctccgggt ccagtggttg
    17701 aaccgggagc cgaaaggtcc ggaccaccag gccctgccgt cgtgcggccc gctcccagca
    17761 ccaccgcatg ggggcgtact cctggtcggt gagcaggatt tccccgcccg gcgccagtgc
    17821 caccgacgac gccaccaggt tgaccgcgcc ggtcacgttg gtggtgaagg ccagccgagg
    17881 cggccgggtg ccgaggtatt cggccaggcg ctcgcgtgcg gtccacaaca gcggtggcag
    17941 ctgccgggaa aggaaatcca tcggcgcggc ggccatccgc gcgcggaatc cggtgaccag
    18001 gtcgaacacc ggccggggca gcgggccgca ggaaccggcg ttgagatcgg tggtggcggg
    18061 gtcgaggcac agctggtcac gggccttcgc ccagcctttc tcgaccatgc gcagcacgct
    18121 ccagtaacaa cggatgccga cgggtggaaa aatgcgtggt gacgcaatgc ggaaacgcgt
    18181 gccgagacca ttccccagtt gccgcattgg cgcggcgaac tgccgacctg gccggcagcc
    18241 gatgtggaaa ggctaccagt cgcgtcggct ccttggcaaa gaaaaaccac cccgatgcgg
    18301 gatgccgacc ggctggcgta ctccggtcgc cgttaaaaaa gccttgtgta ccaaggattc
    18361 gcgcgctcca tcgggaaacg ggtacgggcc agtgccgatc ttggggcggc gcgtggcacg
    18421 tcaccccaat ggcggttccc ggcccggctc gcgctgttag cctcggtcgt gtggcgaact
    18481 aactgccatg cgttgatgtg cgctgatcct tttcatggcg cgttcagctg gcataaacaa
    18541 cttcggtatt ggcaccggtg gtgaaactgt gtgcctggcg ccggtagacg ctgggggaca
    18601 agcagtatgg tgatggaaac accggtgcgc gcaccggccg cgcacgaggt gcgccaggtg
    18661 ctcgcgcgcc acgtgctcac cgatggttac gacctggtgc tcgatctctc ggcgagttcg
    18721 ggttgctggc tcgtcgacgc cgtcaccggc acccgttatc tcgatctttt ctcattcttc
    18781 gcctcgtcgc cgctcgggat caacccgtcc tgcatcgtgg acgacgaggc cttcgtcgcc
    18841 gaactcgccg cggcggcggt gaacaagccg tcgaacccgg acgtctacac cgtgccctac
    18901 gccaggttcg tcaccacctt cgcccgcgtg ctgggcgatc cgctgctgcc gcacctgttc
    18961 ttcgtcgacg gcggcgcgct ggcggtggag aacgcgctga aggcggcctt cgactggaag
    19021 gcgcagaaac tcgggctgga cgacgcggcg gtgaaccggc tgcaggtgct gcacctggag
    19081 cggtccttcc acggccgcag cgggtacacg ctgtcgctga ccaacaccga accggcgaaa
    19141 accacgcgtt accccaagtt cgactggccg cgcatcccgg caccggcgct gcggcacccg
    19201 gaatcggtgt acgcggaaga gaatcggcga gccgagcgcc aggcgctcga agccgccgaa
    19261 gcggcgttcc gcgccgcgga cggcatgatc gcctgcttcc tcgccgagcc gatccagggc
    19321 gagggcgggg acaaccactt cagcgccggg tttctccagg ccatgcagga actctgccgt
    19381 cgtcacgacg cgctgttcgt gctcgacgag gtgcagagcg gctgcggcat caccggcacc
    19441 gcctgggcct accagcaact gggcctgcgc ccggacctgg tggccttcgg caagaagacc
    19501 caggtgtgcg gggtgatggg cggcggccgg atcgacgagg tgcccggcaa cgtgttcgcg
    19561 gtctcttcgc ggatcagctc cacctggggt ggcaacctgg ccgacatggt ccgcgccacc
    19621 agggtgctgg agacgatcga acgcacgcgg ctgctggaca ccgtggtgca gcgcgggaaa
    19681 tacctgcgtg acgggctcga agcactggcg gagcgccatc cggccgtgct caccaacgcg
    19741 cgcggtcgcg gcctgatgtg cgccgtcgac ctgcccggca cgggccaccg ggacgaggtg
    19801 ctgcgccgga tgtacgccgg ccaccaggtg atcgcgctgc cgtgcggccc gcgtggcctg
    19861 cggttccggc cgccgctgac gatcaccgaa agcgagatcg accgcgggct cgaagcgctg
    19921 gccgccagcg cggccccggc gagctgacgt accccgatcg aacctccccg ccgtttcctg
    19981 acgagaagga actccactcg atgacgtcgg caaaacacct gaagaccgcc gcggactggt
    20041 gcgagcgcat cgccgcgatc gccggtcagc gctgcgacct ggagatgttg ctcaaggacc
    20101 agtggcggca ccgggtcgcc gtccgcgacg acgacccggc ggtccgggcc tcccagcgcc
    20161 aggaactggt ttttgccggc caggactaca ccgcgctgaa ggaggcggtg gacggcggtg
    20221 cttccctcgg cgcgtacgcg ctcgccacgc tgcacagcgt gctgcacgcc tacgggcacg
    20281 ggcaccagac cgtggtcgcc ttcctccagc acgaccgggt gctcccggtg ctcgtcgacc
    20341 acctcgcgca gggcgggctg agctgcgcca ccgcggtcga gcggatcgac gaagcggtgc
    20401 ggcggccgga caactacctg gcgcggccgg agttgttgca gcgcgggctg ttcgacgcgc
    20461 tgctcgtgct caccgaccgg ccgctcaccc tggctgaact gccgccgtcg ccgctggtgg
    20521 tgatcgtgcg ggacgacccg gcggcacgct gcctgcgctg gacgctggcc tacgccgggg
    20581 agctgttcga ggacaagatc atcgcgggcg tgctcgacgt cgcgcgggag gtgctcggcc
    20641 agttcgcgcg ccgacccgaa cagctcgtcg ccgatctcga cctggtgtcg gcggaccagg
    20701 aactgcggct gcaccagtgg aacggcaccg acggcgagtt cgacgaggag caccggctca
    20761 acgagctgtt cgaagatgtg gtgcggcgtg cgccggaccg tgaggcggtg gtctgcggtg
    20821 acctcagcct gacctatcgc gagatcaacg agcgggccaa ccggttcgcg cactggctgc
    20881 tcgaggtgcc ggtgcggcgc ggggacctga tcgggctcta cctcgacaag agcgacctcg
    20941 gcgtggtggc caccttcggc atctggaagg cgggcgcggc ctacgtgccg atcgacccgg
    21001 gttatccggc cgagcgcatc cgcttcatcg ccggtgacac cgggctgtcc ggcatcgtga
    21061 cgaaccggcg gcacgcggcg cgcctgcgcg aagtcctcgc cgccgagcac ccgtcggtgc
    21121 gggtcatcga aatcgaaacg gtgctggccg agcggcagcc ggaggccgcg cgcgagaacc
    21181 cgcgcctgga gctgagcagc caggaccgcg cgtacgtcac ctacacctcg ggcaccaccg
    21241 gggtgcccaa gggcgtgccg aagtaccact acagcgtggt caacagcatc accgacctct
    21301 ccgagcgcta cgacatgcgg cgcgccggca ccgaacgcgt cgcgctcttc gcctcctacg
    21361 tgttcgagcc gcacctgcgc cagacgctga tcgcgttgct caacgagcag accctggtga
    21421 tcgtgcccga cgacgtgcgc ctcgaccccg accgcttccc ctcctacatc gagcgccacg
    21481 gcgtcaccta tctcaacgcc accgggtccg tgctccagca cttcgacctg cggcgctgcc
    21541 cgagcctgcg caagctgctg ctggtcggcg aggaactgac cgcggcgggc ctgcggcagc
    21601 tgcgtgagaa gtactccggg cacgtggtca acgaatacgc cttcaccgag gccgcctttg
    21661 tcaccgccac caaggagttc gcgccgggcg tgaccgagcg ccgcgaccgc agcatcggca
    21721 ggccgctgcg caacgtcaag tggtacgtgc tcagccagga cctcaaacag ttgccgatcg
    21781 gcgcgatcgg agagctgtac atcggcggct gcggggtcgc gcccggatac ctcaaccggg
    21841 acgacctgac cgccgagcgc ttcaccgcga acccgttcca gaccgaggag gagaaggcac
    21901 gcggccgcaa cggcaggctc taccggaccg gcgacctcgc gcgggtgctg ctcaacggcg
    21961 aggtcgagtt catgggccgc gccgacttcc agctgaagct gaacggcgtc cgcgtggagc
    22021 cgggggagat cgaggcgcag gccaccgaat tccccggggt gcgcaagtgc gtggtggtgg
    22081 cgaaggagac cgccgccggt ggccgtcacc tcgtcggtta ctacgttccc gaggaatcgg
    22141 cgcgggtcgc cgaagacgag ctgctggcct tcctcgaaca acggctcatc cggatcatgg
    22201 tcccggcgcg gatggtgccg ttgtccagca ttccggtcaa cgtcaacggc aaggtggact
    22261 ggcgtgcgct gcccgacgtg cgcatcgacc agcctgagca cgcgcccgcg gacggcgtga
    22321 ccgggcggtt gcgggagatc tggagcgagg tgctcggggt gcccgccggc cggatcggtg
    22381 accacgacga cttcttccgg ctcggcggcc agagcattct gtgcatcctg ctgatcgcca
    22441 gggtgcggca gcggctcggc cggtccctcg gcgtggagga cgtgttctcc ctgcgcacgc
    22501 tgggcgcgct ggccgggtac ctggaacagc aggcacaaga cgccgaagcg gcgtcggtgg
    22561 ccgacgaggt caccaccggt ggcgcgccgg tccgcctgct cgccaacggc ctgcagcagg
    22621 gcctgctcta ccaccacctg aaaaccgcgg gcggcgacga cgcgtacgtc gtgcagtcgg
    22681 tgcaccacta ccacgcaccc atccggccgg agctgatgaa ggacgcgtgg cagcacgcca
    22741 ggcggaagta cccggcactg cggttgcgct tcgcatgggg cgacgacccc gtccagatcg
    22801 tcgacaacga tgacaagccg gtcgactggc gcttcgccga cctgagcgag gtcagtgacg
    22861 ccgaagcgcg gatccgcgag ttgcaggaac gcgaccgcac cgagccctac gaactggccg
    22921 gcggcaggct gttccgcgtc tacctgatca agcagcgcga ggacctgttc acgctgatct
    22981 tcagctgtca ccacatcatc ctggacggct ggagcctgcc ggtcctgcac gacgaggtgc
    23041 accgggccta cctcgccctg tgcaccggcg cgccgctcga gtccgaagtg gacaaagcgt
    23101 acgtggcggc gcagcggtac tgggaagcgc accgcgacga ccacaccgcc tactgggccg
    23161 agcggatcgc ccggatagac gagcgcggtg atctcgccgg gctgctcaac gagcgcagcc
    23221 ggtaccgggt ctcgctcgcc gactacgacc acgtgcggga gcaccggacc aggaagctgt
    23281 gcctcggcgc gggcctcacc gccgcgctca aggcgggctg cgccgccgac caggtgaccc
    23341 tgcactcggt gctgcagttc gtctggcacc aggtgctcca cgccatcggc ggcggcacca
    23401 ccaccgtggt cggcaccatc gtttccggcc gcaacctgcc ggtggacggc atcgagcact
    23461 cggcaggcct gttcatcaac acgctgccgc tgatcgtgga ccaccgggag caggccggcc
    23521 gcagcgtcgc cgaggcggtc cgcgaaatcc aggccacggt gaacacgatg aacggcaaga
    23581 gcgtggtgga actgggcagg ctgcacagcg gtgagctcaa gcgccgcctg ttcgacacgc
    23641 tgctggtgct ggagaactac ccgcgcctgc tggacgaggc cgaggaacgg gcgcaccagg
    23701 aacaactgcg gttcgaaaag gcctatgacg ccgacaaggt ggactacccg atcgccgtgg
    23761 tggcacggga agaaggcgac gagctgaccg tcaccctgtg gtacgcgggt gagctgttcg
    23821 acgaagacac catcgacacc ctgctcgagg ttgcgcggac gttgttccgc caggtggccg
    23881 aggacatctc gcggccggtc cgcgaactgg agctggtttc gccggaaatg ctggcgcggt
    23941 tcgattcctg gaacgagacc gacgaagagt ttccggcgga caagacgctg cacgcggtgt
    24001 tcgaggagat ggccgcgcgc tggccggacg aaatcgcggt ggtgtaccgg gaaaaccggc
    24061 tgacctaccg tgagctgaac gagcgggcca accggctggc gcactacctg cgctcggtgg
    24121 ccgaactgcg gccggacgac ctcgtcgcgc tgatggtgga caagagcgaa ctgatgatcg
    24181 tggcgatcat cgccgcgtgg aaaaccggcg cggcctacgt gccgatcgac tccggttatc
    24241 cggacgaccg gatctcgttc atgctggcgg acaccgccgc gcgcctggtg gtgaccaacg
    24301 agatccacag cgaacggctg cgcgcgctgc ccggcgcgga aacccggcac gtactggaaa
    24361 tcgagctgct gcacctcggc gaccagccgg cggagaaccc ggtcacgcag accaccagca
    24421 ccgatctcgc ctacgccatc tacacctcgg gcaccaccgg caagcccaag gcggtgttgg
    24481 tcgaacaccg cggcgtggtc aatctccagg tgtcgctggc gaagttgttc gggctggcca
    24541 aggaacgcgg ggacgaggcg ttgctgtcgt tctcgaacta catcttcgac cacttcgtag
    24601 agcagatgac cgacgcgctg ctcaacgggc agaagctggt ggtgctggac gacaccatgc
    24661 gcaccgaacc cgagcgcctg taccggtacc tgaacgacga gcgggtcacc tacctgtccg
    24721 gcacgccgtc ggtgctgtcg ctgtacgact actcgacggc gaccacgctc acccggatcg
    24781 acgccatcgg cgaggacttc accgagccgg tgttcggcaa gatccgcggc accttcggcg
    24841 ggctgatcat caacgggtac gggcccaccg aggtgtcgat caccagccac aagcggccct
    24901 acccgccgga cgtgccgcgg gtgaacaaga gcatcggttt cccggtcgcc aacacccggt
    24961 gctatgtgct gaacgaggcg atgaagcggg tgccggtcgg cgggatcggc gagctgtacc
    25021 tcggcgggat cggcgtggca cggggttatc tcaaccgcga ggacctgacc gccgagcggt
    25081 tcctggacaa cccgttccag accccggagg agcggcggcg cggggagaac ggccgcctct
    25141 acaaaaccgg cgacctggtg cgctggctgc ccaacggcga ggtggagtac ctcggccgca
    25201 ccgatctcca ggtgaagatc cgcggccagc gcgtggaact cggcgaggtg gaggcggcgc
    25261 tgtcgtccta tccgggcgtg gtgcggtcgc tggtggtggc gcgtgagcac acgccggggc
    25321 agaagtacct cgtcggtttc tacgtcggcg accaggagtt cgacgagccg gacctcaagc
    25381 agtggatgcg ccggcagctg cccgaatcgg tggtgccggc gcgggtcctg cggatcaccg
    25441 acatcccggt gacgccgagc gggaagctgg acacccggcg gctgccggaa accgacttcg
    25501 gggcgggcga gggcgccgag tacgtcgcgc cggtcagcga gtgcgagctg aagctgtgcg
    25561 gcatctgggc ccaggtgctg ggcatcgcgc cggaccgcat cggcgcgcac gacgacttct
    25621 tcgcgctcgg cggggacagc attcgcgcga tggcgctggc gcaggcgatc accaccggct
    25681 tcggccaggg gctgggcgtg gcgacggtgc tccagcacac cacgctcgcc gcgcaggccg
    25741 agcacatcca ggctgccgcg ctcgagcagg cgtggacgcc gctgcccgcg gccgccgagc
    25801 acccgccggt ctcgctcgcg caggaacgcc tgctgttcat cgatgacttc gaaggcggta
    25861 ccgccgccta caacatcccg ttcgcgctcc ggctgccggt gaccgaccgg gacgtggtcg
    25921 cgggcgcgct gcgcacgctc gtcggacggc acccggcgtt gcgcacgctg ctcaagtccg
    25981 acggccacgg ggtgcggcgg cagttcaccg ttccggcgga ccaggccgca ccccggctcg
    26041 aagtgaccac agtggacagt gtggcgaagc tggacgaagt gctcgtcgag cacgccgccc
    26101 acgtgttccg cctgcacgag gaactgccca tccgcgccga gctggtcgag cacggcgacg
    26161 agtgctacct gagcgtcgtg gtgcaccaca cctgcttcga cggctggtcg tgggacatct
    26221 tccgccggga gctggcggcc ctgctcgacg gcgtgcccga agccgaactc ggctcgcttc
    26281 gcggtaccta cgctgagttc gcggtgtggc aacggcagta cctgaccggc gggcggttgt
    26341 ccgcgctcac cgcgttctgg acggacgcgc tcgccgggtt cgagacgatc aacctgccgc
    26401 tggaccaccc gcgcccgccg cgcttcgact accgcggccg cgagctggag ttccaggtgg
    26461 acgagcggac caccgaagcg ctgcgcgaac tggccaggac caccagggtg agcctgtaca
    26521 gcgtgctgct cggtgcgtgg tgcgtggtgc tcaacctgta caccgggcag cacgatctgg
    26581 tggtcggcac gccgtcggcg aaccgcgggc gcccggagtt cgaccgcacc atcggcttct
    26641 tcgcgaacct gctggccttg cgggtccgcg tggacccggc ggcgaccgtg cccgcgtacg
    26701 tgcgctcggt cggtgaggtc gtggtcgccg cccaggtgca cggcgaactg ccgttcgagc
    26761 agctggtcaa ggagctggcg gtggagcagg atccgagccg tcatccggtg ctgcaggtca
    26821 acttcaccgt gcagaacgtc tccgatcaca cgagcgcgct gaccgagtac aagccggacg
    26881 ccgatggctg gaccaccacc aagttcgacc tgtcggccac gctgaccgag accgcgaccg
    26941 ggctcgcggg caatctgacc tacgccgcct cgctgttcga agacagcagc gccggcggca
    27001 tcatcgccac cttcgagcac gtgctggccg agttcgccgc gtcggcggcc gacaccccgg
    27061 tcgcccggct cagcgcggtc ggcgagccgg agcaggacgc gctgctgcgg cccgcggccg
    27121 agccgccggt ccagcggacc cggacgctgc acgcggtgtt cgaggaggtg gccgcgacct
    27181 ggccggatga gatcgccgtg gtccacggcg ccacccggct gagctaccgc gagctgaacg
    27241 agcgggccaa ccggctcgcg caccacctgc ggtcggcggg cgggctgcgg cccgacgacc
    27301 tggtcgggct ggtgctggac cagaccgagc tgaccgtcgt cgcgatcctc gcggtgtgga
    27361 aggccggtgc ggcctacgtg ccggtcgacc cgggctatcc ggacgaccgg atctcgttca
    27421 tgctcgcgga caccggcgcg aagctggtgc tcgccggcga agcccacggt tcgcgggtgc
    27481 gcggcctgac cgcggcgaag gtgctcgacc tcgaactgct cgacctggcc ggtgagtccg
    27541 ccgaaaaccc ggtcaccgag accaccggca ccgagctggc ctacgcgatc tacacctcgg
    27601 gcaccaccgg caggcccaag gcggtgctcg tctcgcacgg ttcggccgac agcttccgcg
    27661 cgcagctgag tgggcgctac ttcggcacgc cggacgagca gcgcgaagcc gtgttgttcc
    27721 tgtcgaacta cgtgttcgac ttctccgtcg agcaactcgc gctgtccgtg ctcgccgggc
    27781 acaagctgat cgtgccgccg ccgtcggccg ccggtgatcc ggagttctac gcgctggcga
    27841 accgcgaggg cctgagctac ctcagcggca ccccgaccca ggtgcagcgc ttcgacctgg
    27901 cccggctgac gcacctgcgc tgcgtgctgg tcgccgggga ggcgttccgg ccgcagcact
    27961 tcgacaagat ccgcggtgag ttcggcggcc cgatcctcaa cgcctacggc accaccgaaa
    28021 ccaccgtgta caacaccgtg caccgcttcg aacccggcga gccccaccgg aacacgctcg
    28081 gcgcgccgct cggcaacaca cggctgtacg tgctgggtga cgggatgaag ctgctgcccg
    28141 cgggcgcggt cggtgagctg tacctgggcg gcgaatgcgt caccgagggg tacctgcacc
    28201 ggcccgagct gaccgccgag cggttcgtgc cgaatccgtt cccggccgag gccgcccggt
    28261 acccgatgct ctaccggacc ggcgacgtgg tccggcgcgg gcaggacggc gaactgcggt
    28321 acctgggccg caacgacgcc caggtgaaga tcaacgggct gcggatcgaa ccgggcgagg
    28381 tcgaagcggt gctggcgagt tgtcccggcg tgcgccagtg cgcggtggtc gccggggcgg
    28441 acccgctggc gcccgagcgc acccgcctgg tcggctacta cctgcccgag cccggcacgg
    28501 cggtcaacga gaacgacctg ttcgacgcgc tgcgcgggcg gctgatgccg agcatggtgc
    28561 cgtcactgct ggtccggctc gaccgcccgc tgccgatgac gatcaccggc aagctggacg
    28621 tggccgcgtt gcccagcgcg gacttcacgc cgaagcgcgc ggcctacgcg gcacctcgcg
    28681 accgcgtcga agcacggctg tgccagctgt ggagcgagca cctgccgggt ggttcggccg
    28741 gtatcgacga cgactacttc cgctcgggcg gggacagcat cagcgcgctg cggctggccg
    28801 cccaggtgca gcgggagttc gagcgcaaga tcagcgtcaa gcacctcttc gaccacccga
    28861 ccgtgcggca gttcgcggcc aacgtgcttt ccgggctgga ggacggcccg ccgagtggcg
    28921 aggaagccga gcagggccgg ttgaccggtg actgcccgct gctgcccatc caggagtggt
    28981 tcttcgccaa gccgctgccc gaaccgcacc ggtggaacca caacttcgcg atccgcacgc
    29041 cggcgctgga ccccgggcgg ctgcgtgccg cactggaccg gctgaccgac caccacgacg
    29101 ccttccggct gcggtttccc gagccgggca agcaggtcta cgccgacaac gccccgccgg
    29161 tgacgttgca cgaactcgac gtgcggcagg ccgatgtccg gcagcggctg atcgactggc
    29221 agagcgagtt cgacctggcg cacgggccca cggcggtcgt ggcctacctg cacggtttcg
    29281 acgacggcag cgcgcgggtc tggttcgcga tgcaccacct cgtggtcgac acggtcagct
    29341 ggcgcatcct cgcccaggac ctggagatcc tgtacaacgg cggcgacctg ggcgcgaagt
    29401 ccggcagtta ccggcagtgg gcgcgggcgg tgcgcgagta cgccccggac gacgaggaac
    29461 gccggttctg ggcggaaacc acgcgggaca tggagcccgc ggaggcgctg acgcggacgg
    29521 acagcacccg gcgccgcgag gagttcgcgc tcaccgccga gcacaccgcg accctgctca
    29581 cggacagccc gtgggcctac gacaccgagg tcaacgacct gctgctgacc gcgaccgggt
    29641 tcgcgttgcg gtccatcacc cgccaggcca ccaaccacgt caccgtcgaa gggcacggcc
    29701 gcgaactgtt cgacggcgcg ccggacgtgc gtgacaccgt cggctggttc accaccatgc
    29761 accccttcgc cgtcgaagtg gatcccggcg acctcgggcg cagcattctc accaccaagg
    29821 cgaaccggcg gcgcgttccg caccacggca tcggctacgg cgccctgtcc ggtggccggg
    29881 cgccgcttcc ggtggtcagc ttcaactacc tcggccggct cgggaccgcg gtgacagaga
    29941 cgatggagcc ggtcgaggcg tggcacctcg acccggcgat gtcgggtagc cacaccacgg
    30001 atcgcaaccg cgcggcgaac ccggccggca tcgacgtgac gatgagctgc gtcggcggac
    30061 ggctcaccgc ggtggtggac agcctgctcg gcgaagcggc cacccgcctg ttcgccagcg
    30121 agctgaaggt gtggctggaa cggctgatca cccacaccgc gacccgcgcc cgcaacgaac
    30181 ccgcccgtgc caccgaaccg ttcgatccgt acatcctggt caacgaggaa gccgagcgga
    30241 cgttgttcgt gctgccgccg ggggaaggtg gcgcggagag ctacctgagc aatctcgcgc
    30301 ggcagctgac ggaccaccgg ctggtgttgt tcaacaacgt gcacctgcac acgcccatgg
    30361 gttcgttcga ggaactgggc cgctactaca ccgagcacct gcggcggttg cagccgtccg
    30421 ggccgtacca cctgctcggc tggagcttcg gcggcgtgct gtcgctggag atcgcccggc
    30481 ggctcgcgcg ggcgggggag cggatcgcca gcctgctgct gatcgacccg tacttcggca
    30541 tgcggcaggc ctcggcgagc atcggcctgc ccgaggtcga ggacattctc gacccgatca
    30601 actaccacta ccagccggac gaagcggatc tcgcgcggct cgccgaccgg ctcggggagg
    30661 tggtgctgtt ccaggctggc gagctgaacg acgtggtgaa cggcccgcac cagccgcggt
    30721 tgttcgagtt ctaccagcgc acgcgccaca acaatctcga cctcctgctg cccgccgaac
    30781 ggatcgaggt cgaggtgctg gcgggggaga cccaccattc gtgggtgcgc aacgaggagc
    30841 tggtcaaggc gatgtgcgag cggatttcga cgagcacagg gagaagttca tgaaaatgcc
    30901 gtcagcagag gtgccgacca tcgacgtctc gccgttgttc gggaccagcg ccgaggaaaa
    30961 gatgcgcgtc ggccaggaaa tcaacaaggc ctgccgcggc tcgggtttct tctacgcggc
    31021 caaccacggc gtcgacgtgc agcagttgca ggacgtggtg aacgaattcc accggacgat
    31081 gaccgaccag gagaagtacg acctggccat caacgcctac aacaagaaca acccgcacgt
    31141 gcgcaacggc tactacatgg cgatcaaggg caagaaggcg gtcgagtcct tctgctacct
    31201 gaacccgtcc ttctccgagg accacccgga gatcaaggcg ggcacgccga tgcacgaggt
    31261 gaacatctgg ccggacgagg aacggcaccc gcggttccgg ccgttctgcg agcagtacta
    31321 ctggaccatg caccggctgt ccaagacgct gatgcgcgga ttcgcgctgg cgctgggaaa
    31381 gccggaggag ttcttcgagc cggagctgaa agaacaggac acgctttctt cggtttcgct
    31441 gatccggtac ccgtacctgg aggactaccc gccggtgaaa accgggcccg acggcatgaa
    31501 gctgagcttc gaggaccact tcgacgtctc gatgatcacc gtgctgttcc agaccgaggt
    31561 gcagaacctc caggtggaaa ccgtggacgg ctggcaggac ctgcccacct cggaccgcca
    31621 cttcctggtc aacgccggca cctacctggc gcacctgacc cacgactact tcccggcccc
    31681 gctgcaccgg gtgaagttcg tcaacgcgga acgcctgtcg ctgccgttct tcttccacgc
    31741 cgggcagcac acgctgatcg agcccttcca ccccgacggc gtgccggacg gcgagcgcaa
    31801 cgaggccgtc cggtacggcg actacctcaa ccacggtctg cactcgctga tcgtgaagaa
    31861 cgggcagacc tgaggagcag gcgatgacgg acaccttcct ggacctgaac cagttccggg
    31921 ggctggggga ggacccggtc taccacccgc cggtgctggc cgaccggcca cgcgactggc
    31981 cgctcgaccg ctgggccgag gcaccccgcg acctcggtta cccggacttc gcccggtacc
    32041 agtggcgcgg gctgcgcctg ctgaaggacc cggacacgca ggccgcctac cacgacctgc
    32101 tgtgcgagct gcgcccgcgc accatcatcg agctgggcgt gtacagcggt ggctcgctgg
    32161 tgtggttccg cgacctggcc gacctgatgg gcctggactg ccaggtgctc ggcatcgacc
    32221 gggacctgag ccggtgccag atccccgatg cggagatgaa gaacatctcg ctgcgcgagg
    32281 ccgactgcgc cgatctgtcg accttcgagc agctccgcga cctgccgcac ccgctggtgc
    32341 tgatcgacga cgcgcacgcg aacaccttca acatcctgcg ctggtcggtg gaccacctcc
    32401 tggtcgaagg cgactacttc atcatcgagg acatgatccc gtactggcac cggtactgcc
    32461 cgaagctgct gaccgagtac ctggccgcgt tccgcggtga gctgaccatg gacatggtct
    32521 acgccaacac cagcgcgcaa ctcgaccgcg gtgtgttccg caggtcggcg taggcggagg
    32581 tggggcgttg ccgagggtat cgagcccgct gtactacgcc gcgccgctga ccccggcggg
    32641 ccgggccgac gactggtgca tcgacgcggt gacccggccg ccggaggtgc tgttcaactt
    32701 ccgcaaggtg ggcgtggaaa cgctcatcga ggacctgcgg gagggtgcgc tccggccgtc
    32761 gctcgacgag acggggttcg agaaggccga cgcggagtcc acagtggacc atcgggacct
    32821 gctggacaat gacgagaccg cactggaggc ctaccgcaag gaaaccggtg agctgctcaa
    32881 ggcgctcacc ggcgccgacg cggtggagtt cttcgacgcc acgctgcggc ggcaggacgc
    32941 gtccggtgat ccggccgcgc agtcgccgca ccagcgggtg cacgtggacc agagcccgcg
    33001 aagcgcgctg gcccgcgcct tgaaccggcg ggcaccgggg gagttccgcc ggttccagat
    33061 catcaacgtc tggcggccgc tgctcgaacc ggtgcgcaac ttcccgctcg ccctctgcga
    33121 cttccgctcg ctcgacctcg tcgccgatct ggtgccgacg cggctggact tcccggactg
    33181 gctcaaggac cgggaaaact actcggtccg gcacaatccg aaacaccgtt ggtaccactg
    33241 ggattcgctc acgccggacg aagcactggt cttcaagtgc cacgacagcg cgagccgcgc
    33301 cctggcctcg gtcggcggcg aaaccgcgag cggcgagctg ctcgacgtgg cgggcctctg
    33361 cccgcacacg gccttctacg accacaacgg accgtcgacc ggccacctgc gcacctcact
    33421 cgaactgcgc gcgctggcct tccacgaatg accgacaagc aaggagcacg ggaaatggcg
    33481 gacagcacgg taccggtttt caccatgacc gaactgcgcg agggcacacg ccaggcggag
    33541 ttccgcgagt ggacccggcg cggggtcttc tacctgaccg gctacggcgc caccgagcag
    33601 gaccaccggc tggccaccga caccgcgatg gacttcttcc agcacggcac cgccaccgag
    33661 aagcaggccg tgaccacgga catcccgacc ctgcggcggg gttattcggc gctggaggcg
    33721 gaaagcacgg cccaggtcac caacaccggc acctacaccg actattcgat gtcgtactcg
    33781 atgggcatcg gcggcaatct cttcccgtcg gagaagttcg aagcggtgtg gacgcactac
    33841 ttcgacaccc tgtaccgagc cgcgcaggag accgcgcgcc tggtgctgac cgcgccgggc
    33901 acctacgacg gcgaggacct ggacaccctg ctcgactgcg atccggtgct gcgcctgcgc
    33961 tacttccccg aggtacccga gcaccgggcc gccgagtacg agccacgccg gatggccccg
    34021 cactacgacc tgtccatcat caccttcatc caccagaccc cgtgcgccaa cggttttgtc
    34081 agcctgcagg ccgagatcga cggtgaaatg gtgagcctgc cccacatcga ggacgcggtg
    34141 gtggtgctgt gcggcgcgat cgcgccactg gtcacccagg gcgcggtgcc cgcgccgaac
    34201 caccacgtgg tgtcgccgga cgtgagcagg ctcaagggca gcgaccgcac ttcgagcgtg
    34261 ttcttcctgc gcccgtccac cgatttcacc ttctcggtgc ccaaggccag gaagtacggc
    34321 ctcgacgtca gcctggacat ggagaccgcg accttcggcg actggatcgg gtccaactac
    34381 gtcaccatgc actcggtcac cccgtagtcg tcgccccagc gttgaaggag aacgaatgct
    34441 catcgtcgcg ttcaaaccgg ggcacgacgg tgccgtcgcc gcgatcggcg atcgccggtt
    34501 gcgttactcg ctcgaatcgg agaaggattc gcggccgcgg tactcgccga tcctgccgac
    34561 gacgatcctc gacctcgccg aacggctcga cgcggtgccc gacgtggtcg cgctcggcgg
    34621 ctgggccgac ctgcggccca accgcatcgc ctacaccggc gccggttacg cgggcatcga
    34681 tgatccgatc gtgtccaccc ggcggttctt cggcaaagag gtcaagttct tcagttcgac
    34741 gcacgagcgc tcgcacatct acatggcact gggcatggca cccgaggatg acgcgcggga
    34801 acgcgcggtg ctggtctggg aaggggacgt cggcgccttc tacctggtcg gcgcggacca
    34861 gcggatccgg cgcaagatcc cggtgatgag cgcacccggc gcgcggtatt cgttcctctt
    34921 cggcctcgcc gaccccacct tcccggacac cggcgcgaaa ccgcggttga acgacgccgg
    34981 caagctgatg gcgctggccg ccttcggtga cgccgccgac gcgaaccccg acctcaccaa
    35041 cgtggtcgag cgcatcctca agcaggactc gatgtacccg gcgcccaagg ccgagtaccg
    35101 ggattcggtg ctgtacaacg ccggagtcga atcaccggag tgcaagaccg cggccgcgct
    35161 gctcaccgaa cgccttttcg agaccttcgc cgaggtcgcg cggcaggaac tgcccgcggg
    35221 cacaccgctg gccatctccg gcggttgcgg gctgaactgc gactggaaca gcatgtgggc
    35281 gcgtctgggc cacttctcct cggttttcgt ggccccgtgc accaacgact ccggctccgc
    35341 gctgggcacc gccctcgacg cgctggccac cttcaccggt gacccgcgca tcgactggga
    35401 tgtctacagc ggactggagt tcgtcaccga cacccgaccg gaccccggcc ggtggcgtgc
    35461 ccggcccctc gacgaagtcg cgctttccgc cgcgctgggc gcgggccggg tggtggcctg
    35521 ggtgcagggc cggtgggaga tcggcccgcg ggcgctgggc aaccggtcgc tgctggccga
    35581 accgttcagc acggcgacga aggaccggct gaacgagatc aagcagcgcg agggttaccg
    35641 cccgatcgcc cccgtctgcc gcgtcgagga cctgggcacg gtcttccacg aggacttcga
    35701 agacccgtac atgctctact tccggcacgt gcgggagtcc agcggggtgc gcgcggtaac
    35761 ccatgtggac ggttcggcca gggtgcagac ggtccgggag gcgggcaatc cgcagctcca
    35821 ccggctgctg tcggcgttcg cggcgcagcg gggcgtcggc gtgctgtgca acacctccct
    35881 gaacttcaac ggcgagggtt tcatcaaccg gatgtcggat ctggtgctct actgcgaatc
    35941 acgcggcatc gaggacatgg tcgtcggcgg cacgtggtac cagcgtgccg acggctgacc
    36001 cgcgaaccgg atgacggcga cggccgcggg cccgcggcgg ctcggctacc tggaactcgc
    36061 cgcccggatc accgacgtcg ccggtctcca cctggcacct cccgcgcgga tcctggcact
    36121 ggagctcggc agccggtccg accggccggt gctgcccatg gacccgggca ccgcgagcct
    36181 gttcgcccag ctcgatgcgg cgagcaggcg gcccggcccg gtgcacccgg cggcctgcct
    36241 gcggttcctg acccggctcg agcacgccgt gccgccggag ggggaggtct acctcctctg
    36301 cctggcgcca ccgccggtgg tccgggactg ggtggccgcc cacccgcgct tcaccgcccg
    36361 ccgcccgggc ggcgaagcgc actgggcgga cgaagtcagc cagtgcctgg gacaccgagg
    36421 cgctcgcacg ctgcgacgcc ggaccaggga actggaagcc gggctgcgcc ggtggcacca
    36481 ttcccggcgg gacggagcct tcacctgggt gagggccggg cactgacgcc tggattttta
    36541 tggcacggtg gtgtcggtcc gggcggtggt ggttcgtcgg gctgataagt accggaccac
    36601 cgacgtaagg agaaccatgc acaccgtgac ttccgcggac ggcaccacca tcgcctacga
    36661 ccgggcgggc agcgggccgc tggtcgtttt tgtgcccggc gcgttcaacg accgcaccac
    36721 ctgcgcgggg gtggccgagc agttgcggga ccgctacacc gtcgtctgcc cggaccgccg
    36781 cgggcgtggt gacagcggtg acgccatcgc gcccgccgac gtcgccgcgt acgacgtgcg
    36841 gcgcgagatc gaggacctcg acgcggtgat cgcggccgaa ggcggtcgcg cggctgtctt
    36901 cggcttctcc tccgggggca ccctggccct gcacgccgcc gtcgccgggt cgccgatcac
    36961 caagctggcg ctgtacgaac cgccgttcgc catcggcggg ctcgccggaa gcgcgcgcga
    37021 gggcctgcgt gacaagctgg ccgccctgat caccgccggc cgtcgcggcg acgctgtcgc
    37081 ggccatgcag gtcgagggca tcggcctgcc gccggagctg gtggaccaga tgcggcagtc
    37141 gccgatgtgg ccgcagctcg aagcgatcgc gcagaccgtc gtgtacgacg cgaccatcac
    37201 ccgcgcgccg aacctgccca ccccggagat ggcgcggctg gacctcccgg tcctcgtgct
    37261 cagcggcgcc gaatcgtggc ccggcctggg cgcggccgcc cgggaactcc cggcgcacct
    37321 ggcgaaggcg cgtcatgccg aggtcccggg cggcgcgggc cacgaaatcc ccgccgaggc
    37381 caccgcgaag ctcgtcgacg ccttcttccg cgactgaggg gtcaggccgc ggcacgcaac
    37441 gacgcgacag ccgcggcgat tcccttcttg tcgtagctgc ccgtcggcag ggtggcaccg
    37501 tgcgcatgac ggacgacgcc ctcccggtcg acgaggaggc tgcccgactg ctgcaacgag
    37561 ccgaagacct tccggctcag gcccgccagc tcgtgcgggc ggtcgccggt gagcaccggg
    37621 aaggggatcc ggtgcttcgc cttccaggcg gccgcccgct cgcggtcctc cggcaccgcg
    37681 agcagcacgc ggacgtcgtc ggccgccagt tcgtcggcgc ggttgacgag gtcacggacg
    37741 tgccggaggc agaccgggca cgaggtcgag cgcaggaaga agagcagcac ggcgtgcttg
    37801 ccctggtagt cggacagccg gacgggccgg cccgcggtgt cttccagcac catccggggc
    37861 gccggtgaac cggccttgag catggtcgat cttcctttca cgagggggtt gccgtgtcgc
    37921 gcaggctggt ccggagcgcg gccctggcgc ggtgcaggtg ggacttcatc gccgccgtgc
    37981 tcagcccgag cgccccggcg acggtccggc ccggctggcc cagcacgtca cgcatgatca
    38041 gcacccggcg ctggacgtcg ggcagctccc ggatcgccgc cgcgaccacc tcggcgtcga
    38101 gccgcctgag cacctcgtcc tcggcggatg cgacgggatc ggtccggtcg tggtgatcgg
    38161 ccaggcgccg ggcccgccgg aggcattcgt tccggaccac ccggaacatc cacgacgcga
    38221 gcgcggccgt ggcccgcagc gagccgatct tccggtagag caccagcaac gcttcctgtg
    38281 ccgcgtcctc ggcgtcctgc ggtgaagcgc agagctgacc ggcgaagcgg cgcacgtgcg
    38341 gatgagcccc gtgcaccacc gcggtgatcg actccaggtc accgccctga gcggccttga
    38401 tcagctgctc actcgcccag ccacggtcca ccacgtcctc caccccgttc gagccacgcc
    38461 gaaaccaaca accataagag gcagcgcccc cgcgaaagga ttcacctagg ctggctccgg
    38521 cgaagatcga aaggacgctc cggtgctggt cgatgcgcac gtccacgtgg tggacttcct
    38581 gcaggacagg ctcacgccgg cggacttcgc gcggaagctg gccggcgccg gcgcggaccg
    38641 cgcggtgatc tgcgggctgc cgatgaaaaa gaagtggccg gtcaacgaac cccgcaagcc
    38701 gggctactac ctcgacggca acgcgccctg ccagtactac tcgctgaccg acgagctggt
    38761 ggcgagcctg cacgcggaac tcccgcccga gctggccggg cgcgtggcgc cgacgctgtg
    38821 cgggttcgac cccaccgacc ggctcgccat cgagcacgtg gagctggtgt ggtcccggca
    38881 cgacagctgg cgcggcatcg gcgaggtcat gctccgccac gacgacctga ccaacctcac
    38941 caggggtgag aacccgtgcg cggaccacct cgcgctcgac ccggtgttcg acttcgccgc
    39001 cgagcgcggg gtgccgatcg cggtgcacca cgacagcagc tcgccgggac ggccgggaca
    39061 gcacgagtac gtcgaccagc tcgccaccat gctgcggcgg cacccgcgca ccacggtggt
    39121 ctggtgccac ggcggggtgt cgcgccgggt ggagccgaag gaccagggca ccgtggtcgc
    39181 cgacctgctc gacgcccatc cccggctgca cgtggacctg tcgtgggcgc tgctggacca
    39241 catcctcgac cacggccgcc tgatccccca atggcgcgag ctgatcctgg cccggccgga
    39301 ccggttcgtc tgcggcagcg acgtggtggg cccgcggtcg gactgggcgg cggccaccgc
    39361 ccggctgcgt cagctgctgg acgacctgcc acccgcggaa cgggaggccg tcgcgtgcgg
    39421 caacgcgctc cggctgtggt ggcgggagtg aaacctcagg gcttgcggcc caccgcgccg
    39481 acgatgcact gctccacctg gttcagcggc cgcggccgcg ggccctccgg ccaccacagg
    39541 tcgcacagtt cgaggtcgcc cggcttctcc gggttcggcg gcaccagttc cagcccgggg
    39601 aagaaggccc tgatctcgtc cgcggtgcgg aaccgccccg accccatcgg gctgtggatg
    39661 aagatgtcct ccatccgctc ggcgaggtgc gcgagttcgt cggtcccggg attgaagaag
    39721 tgcgcgatcg ccacgtagct gcccgagggc agggcgtcca cgtactccgc catcagctcg
    39781 gccccgttgt cggcggtgta gtggtgcagc gtgcccacct gcagcagggc cagcggctcg
    39841 gtgaagtcga tgtgctcccg caccacctcg ttgcccagca cctccgacgg ggtgaagatg
    39901 tccgcgtcgg cgaagtgggt gcggtcgttc tccaccagca gcgcctgccc gtgtgagatc
    39961 accaccgggt cgttgtccac gtagaccacc cggcagtccg ggtcgatccg ctgcaccacc
    40021 tggtgggtgt tctccgcggt gggcagcccg gagccgcagt cgaggaactg cttgatcccg
    40081 gcccgcatgg cgaggaagcg gcaggcgcgg atcaggaact tgcggttgct ccaggcgaga
    40141 tcgttgacct cgggcgccac cttggcgacg cgggccagca cttcgcggtc gatctcgtag
    40201 ttgtccttgc cgcccagtgc cgcgtcgtac acccgcgcga tgctggcgcg gttcgggtcc
    40261 acccccaccg ggttcgagct cggcgcccgg tacttgtcgg tcatcctgcc cctcgaagct
    40321 cagccgtacg tgaggggcag cgtactgctc gtgtccgctg cgtcaccacc cgcgggtggt
    40381 accgctcctg gccagccgcg ggatcaggcc accggccagc accgcgtcga cttgttcggc
    40441 ggaaagccgg tgccgcagcc ggtaccgttc gtccttgctc tggttgcgca cggtgacttc
    40501 cggatggtcc gcgtgcagcg cgcccggcag gtcatcgagc accagcacat cacccggttc
    40561 gatccgctcg tagtcacccg gctcggtgaa ttcgagggcg agcaccccga agttggccag
    40621 gttctgccag tggatcctgg cgaacgactt cgccaccacc gcgcgcaggc cgagataccg
    40681 cggggtgatc gcggcgtgct cgcgggacga gccctgcccg tagttttccc cgccgaccac
    40741 gatgtgcccg gtgtccgcga cttcgcgggc gcgggccggg tagtcctcgt cgagccgggt
    40801 gaaggtgaac tcggcgagct tcggcacgtt cgaccggtag gggagggcac gcgccccggc
    40861 cggggagatt tcgtcggtgg agacgtcgtc gccgagcttg agcagcaccg gcgcctcgac
    40921 ccggtcgggc aggggcggga agtccggcag ggtcgagatg ttggggcccc gcacgaggtc
    40981 ctcgcgcgcg gcttcttccg gcggcagcgg cgggacgagc atgcgggtgt tgaccatcgc
    41041 cttctcgggc aggtccagca cgggcggggc gtcgcccagg tcgcggggat cggtgatgac
    41101 cccggtgagc gcggacgcgg cggcggtttc gggggagcac aaccacaccg agtcgtccgg
    41161 ggtgccggag cggccgggga agttgcgcgg gaaggtccgc agcgagttgc ggcccgccgc
    41221 cggtgcctgg cccatgccga tgcagccgag gcagcccgcc tggtggatgc gcgccccggc
    41281 ggcgatcagc tcggcggtgg cgcccatctt ggtcagatcg gcgaagatct gccgtgacga
    41341 cggattgatg tcgaggctga cctcgtggtc ggcttgcttg ccgcggagaa cggccgcggc
    41401 gatggcgaag tcacgcaggc ccgggttcgc cgacgagccg atcaccacct ggttcaccgg
    41461 tgtgcccgcc gcctcgcgca cgggcaccac gtcacccggc gaggacggcc tggccaccag
    41521 cggttccaca gtggacagtt caatgtggtc ggtcacgtcg tagccggcgg ccggatcggc
    41581 gcgcagttcg cggaagtcgt cctcgcggtc ctcggcgcgg aggaactcgc gcaccgcgtc
    41641 gtcggcgggg aacaccgtgg tggtggcacc gagctccgcg cccatgttcg cgatgacgtg
    41701 ccggtccatc gccgacagcg tcgccacacc gggcccgtgg tactccacga tccggttcag
    41761 cccgccccgg accccgtggc ggcgcagcat ttccaggatc acgtccttcg ccgacgtcca
    41821 cggcggcagc tcaccggtca gccgcacccc ccagatctcc ggcatgcgca ggcgcagtgg
    41881 ctgcccggcg atggcggtgg ccacttccag cccgcccacg ccgatcgcga gcatgcccag
    41941 cgaaccggcg gcgcaggtgt gcgagtcgga accggccagc gtcttgccgg gcacgccgaa
    42001 ccgctgcatg tgcgtcgggt gggagacccc gttgcccgcc ttggagaacc acaacccgaa
    42061 ccggcggcac gccgactgga ggaacaggtg gtcctcggcg ttcttttcat ccgattggag
    42121 gaggttgtgg tccacgtact gcacgctcac ctcggtgcgc gcgcggtcca ggccgagcgc
    42181 ctccagttcc tgcatcacca gcgtgccggt ggcgtcctgg gtcagcgtct ggtcgacccg
    42241 cagctcgacg gccgcaccgg gttccggctc accgcggacg aggtgctcct cgatcagctt
    42301 ccgtgccagg ttgcgtccca ctccgatggt gtacccgcgg tcctggccgg gtattcgagg
    42361 tgtcatgaac gcgtcgcgga ggcggacccg cgcggagtac gagcgtgggc tgccggacta
    42421 tcacgacccc acggccggtt acggcggtgc cgctccggcg tacagcgcgc tcaccctgcg
    42481 catcgtgctg gcctcggccg cggtggtgct ctgcgtggcc ggtgcggtgt tcttcgtggc
    42541 acaggacgcg gtgtggggcg ccgtcgtgct cggtgtcgtc gccgtggtca gcctggtcga
    42601 cctcggctgg gtggtgcacc ggaaacggcg cggggaaccg ggttgacggc cggtggccga
    42661 ccgtccgggt gatgcccgct gacgtgcggt gaccagccgc cgcacgggcg gtgagtgtgc
    42721 gctttgcgct cggggcgtgc ttctcctacg gtgaacgcac ggttcaaacc atgtgccgcc
    42781 ctttcggagg cttcacctgg ttggtgctgt ctccaccgtc accacggaag gagcagcatg
    42841 gacgccacac cgctgttgac cgtcgagagc cgcttgctgg gaagcaccac ccgcctggtc
    42901 tcggtgtgcg gtgaggtcga cgagagcacg cggccgcggc tggaggccgc gctggccgag
    42961 gtgtgggcgc cgccgtcgcc gttcgcgctg ctggtccacc tgcgcgatac caccttcttc
    43021 ggcagcgccg ggctgcggtg cctgctcgtc gcgcaggcgc aggcacgcgc gcacggggcc
    43081 accttcggcg tctgcgatcc ctcgcgcgcg gcggcgagag ccttgaaagc cgccggcctg
    43141 gacggggttt cccgttgtac cggggcggtc cggcggtctt cgagcagctg tccaactgat
    43201 cagccaccgg aatacttgaa cgcgcaacta aatgcgagta gtagtggcac cgggggccac
    43261 ccgggtccgc tcgctctgca gaggagtctt catgcgcatt gggttcagtc ttccggtctt
    43321 cggcaaggcg acggccacgc cgggcggggt ggcgcggtac gcgcgcgccg ccgaggaagc
    43381 gggggccgcc agcctctggg tcggcgaccg gctgctttca ccggtggcgc ccgaggtggc
    43441 ctatcccggc tacgacacca tgccggagga gttttccatc gcccaggatc cgttcatcct
    43501 gctcgccgtg gcggccgccg tcacggagaa ggtgaccctc ggctccagca ccatcaacgc
    43561 gacgcagtac cagcccgcca ccttcgcgcg gcagctgacc agcatcgacg tggccagcaa
    43621 cggcaggctg ctggccgggc tcggcatcgg ctggtcgccc gacgagtaca acgccgtcgg
    43681 cgtcccgatg gccgagcgcg gcaagcggct ggacgacctg ctcgacctgc tggaggcgtg
    43741 gtggacgaag gacgtggtgg cacaccaggg agtcggttac accattccgg agagccatgt
    43801 cgggctgaag ccggtccgca agccgccggt gtacctggcc ggattcggtg agcgcgcgca
    43861 gcgccgggtc gcggaacggg ccgacggctg gctgccggtg tggtcggtac ccgagcagtt
    43921 ccccgcggaa gcgctcaccg ggggactggc caagatccgc gccgccgccg agaaggccgg
    43981 gcgtgacccg ggggcgctgg gcgtcgcgct gcgcgtgaac gccggacccg ggaccgagcc
    44041 ggaactcctc gccgaagcgg tgaagaagat cgtcccggcg ctcgacgcgg accatgcctt
    44101 cgtcgacctc acctacctca ccagcagcgt ggacgagcac atcgagctca ccggccgcct
    44161 gctggacctg atcggcaagg gctgagcgcg gctcagcagg cgcggcaggc cgagaacccg
    44221 gcgacgtcga acggcgccgc cgggttctcg tcggtggcgc ccacccagcc ggtcgcgcca
    44281 ccgcgacccc gtgccactcg tgggccatcc gggtgacgcg ggaaagtcca cacgttgtcc
    44341 gcaatcctcc acaggtgcct tcctaacctg gttcccgtgc gcggaaacgg aaagaaactg
    44401 accacactca tcgccggcct gctggtggcg gccggcttgg cctggccgcc cgccaccgcg
    44461 acggccgcac cggcgtggcc gacgcccacc gggcaggtca gcgtgaacgg cacgatctcg
    44521 gtgccgtcga gcggcctcga cggcggcatg cgccggtact gctgcatcgg cgacggcggc
    44581 caggaggagg accaggaccc gatgttcctg ctcgctcccg gcgccacgct gcagaacgtg
    44641 atcatcggcg gcccggctgg ggacggcgtg cactgcacgg gtccctgcac gctgcggaac
    44701 gtgtggtggg aggacgtcgg cgaggacgcg gcgaccttcc gcggcagcgg tgatcccgcc
    44761 ttcctggtcg acggcggcgg tgcccgttcg gcgggggaca aggtgttcca gcacaacggg
    44821 ggcggcacgc tgaccgtgca gaacttccag gccggcgact tcggcacgtt ctaccgctcg
    44881 tgcggcaact gctccaccca gtaccagcgc gacgtggtgt tccgggacat cacgctgacc
    44941 cggccgggca accgggtggc gggcgtcaac accaactacg gcgacacggc caggttcagc
    45001 gggctcacca tcgtcggcga ccccgaccgg aagatggtca tctgccagaa gtacatcggc
    45061 aacgacgacg gcgacgaacc cgacgagaac ggctccgggc cggacagcac ccactgccgc
    45121 tactccgcga gcgacatcac ctaccagtag cggcttcata ctcctttctt gcgcaccgaa
    45181 gtcgtgtcgc tggtcagtgg tgagccgtct gcggcgaccg ggacgactgg cgggacgacc
    45241 tcgccgtgtt cgtcgaccag gagcgagtgt ggttcgcctg ggccgaaggc gtggcgctca
    45301 ccccactgcc gaagcgcgac gatcaccgcg aacaggtcct tgcccgcgtc ggtgagggtg
    45361 tacacgcggc gcttgcccga cggggcttcg acctgggtga tcaggccgtg cgtggtgagc
    45421 ttccgcagcc ggtcggtgag gatgttgcgg gcgatgccgg tgcgctgctg gaagtcggtg
    45481 aaggagcgcg ccccgtccat cgcgtcacgg acgatcagca ggctccaccg gtcgccgacc
    45541 acgtccgccg cgcgggcgac cgggcagtcc gggtccgtcc acacctgacg cctcccatga
    45601 gttgcgaatt gaaaccattc tgccctagcc tgcgatgagt tgcaaaatgc aaccaaactc
    45661 ggaggtggtt gtggggcggg gaacgaggct ggtgctggcc gtggtgtgcg gtgtggccgt
    45721 cgccggggtg tatgccgggc agccggtgct ggagccgatg gggcgggacc tcggtatgcc
    45781 gcgggaatcg gtcggctggt tcgtcgccgc cgggcagctc gggtatctcg ccgggctggt
    45841 tctgctggtg ccgctgggtg acctgctcga ccgcaggcgc ctgatcgccg cgcacctggc
    45901 gctggtggcg gccgggctgg cgatcgccgc gaccgcgccc gcggcctggg tggcgctgtg
    45961 cggactcgtg gtggcgggcg ggttcgcggt tgtcgtgcag acggcggtcg ccttcgcggc
    46021 ggcgatctcc ccgcccggcg agcgcgggcg cactctgggt gtggtcacgt cgggggtggt
    46081 ggtcggcatt ctcggcgccc gtgcggtcac cggcggcctc gcggatctgt ggggctggcg
    46141 cagcagctac ctggtgctgg ccgtgctctc cgccgtgctc gctgtggtcg ccttggtggc
    46201 tttgccgacg gacctccggg tggatcggtc ccgatatgga caggtgatcc gtactcttgg
    46261 aggattgttc aacaatccta tttttctcac gcggggactg gttgcgtttt tcctgttcgc
    46321 ctccttcggc acgctctgga gtggcatggc cttaccgctc gccgccgcgc cctggcagct
    46381 gagcgaagcg cagatcgggc tgttcggcgt cgccgggctc gccggtgcgc tgggcgccgc
    46441 ccgcgccgga cgctggggcg acgccgggca caccggccgc gtcaccggca tcgcgctcgt
    46501 gctgctgctc ggctcgtggc tcgcgatcgg gcagctcggc tggtcgctgc ccctgctggt
    46561 gctcggagtg gtggtgctgg acttcgccgt ccaggccgtg cacgtcggca accagcacgt
    46621 gctgaccacc gcctaccccg agcgcaccag cagcgcgatc ggcggctaca tggtcttcta
    46681 ctccctcggg tccgcgttcg gcgccgctgc gaccaccgcg ttgttcgacg cgttcggctg
    46741 ggccggtccc accgtgctcg gcgcgctgct cgccctcggt gcgctcgtca ccgccgctcg
    46801 cggtggacgg tcagcagccg gaccgacgcg gcgaggcagc tcgcgcagcc ggacacgtgc
    46861 tcgtcgacgt gctggatccc ttggtacgaa aggtttccca ccaaccaggt cgggagctgc
    46921 cggcgaaccg gccggcagcc ggtgtgcgcg tgggcctggt gcagctccgt ccggacccgc
    46981 ctgatcagcg cggccgcgcc accgggtgag gtgttcagca cggcggccag gtcctcgtcg
    47041 ggagcgccgg attcgaggtg ccacaacaca agttgccagc gggcggggag acggcggaac
    47101 gcggggccgg tgagctgggc gcgccaccgg cgcaccacgg gttccgcggc gggcggcagc
    47161 gggtggtcca ccgggaggcg ggagcgcagc agcagggccc cgtaggccag caggttcccc
    47221 gcacgcgccg cggtcagcag cgccgtgtcg gtcaggtcct cgttggtgct agtcggcaac
    47281 tcggtgactt tctcgtcggt cttcggttcg ccagaaacgt actcggtgac cggctgggcg
    47341 aagatcgtca ggcacccgaa aaaccgtgag tagtcctttg gtggtgtccc ggctggcccg
    47401 cggtggccgc gtggatcgcc acgcccgctg ctcgggcgga cttccctgac gctgcgtcac
    47461 catgctctgt cctttgagga cggtaggccc gggaccggtc ccgggggtgt ttcgctagca
    47521 tgaggcgcat gatcagccga cggtggcgcg tgccggtcgt catcgcgtgc ggtgtgcttg
    47581 ctgcggcggc cgtcggcgtg acggtctggc tgtcccgcga cgagccgttc gaacccgggg
    47641 cgccgggcta tctggacctc gcctgcggcc tgcatctgca tcaacgggac ctcaatcgcg
    47701 cggccatcga agcggacgac gccgaacagc agctcggcta tgccgtgtcc acgctgttcc
    47761 tggaggtcgg caaccgcgag ctgaacaccc ggctgcagga cctgtcgaac gaactcaagg
    47821 tcgcgctcga cgaggacaac gacgcggcgt tcgaccaggc ccgcgcccgc gccgacgccg
    47881 aatgcggcga gcgcgacgct ttcgcgccgg aaccgggtgc gctggtcgag gtcgcgtgcg
    47941 gcatcgcgga cgtgctggag ccggggcccg gtcctgaact gctgctcacc tcgtcgctga
    48001 tcagcgccgc ggccgaacgc gacgcgcagt acgaggaact ggacaaggcc gcggcccgcc
    48061 tggtgctcga cccggcttcg ccgctggacg ccaaccatcc ggacgccgaa gagatcgccg
    48121 ccttccggaa ccagtgcccg gcctagcccg ctggacacga atgtggcttt cggggcggaa
    48181 aacgccccga aagccacatt cgtgttccta cagcaggccg tccgggagca ggccgagttg
    48241 ccgcagctgc ccgaagacgt ccaccacgcc ccacgtctcg gcgatccggt cgccgtcgaa
    48301 ccggacgatg aagatctcct tgtacgacac ggacttcccg gtcggcgggt ggccgcggta
    48361 gtcgccgaga tgggtgccgg tgacggtgtt gcggaagacg accttgtccc cggcggcgat
    48421 ggtgtcctcg gtggtcaccc ggatgtccgg gaacgcgcgg agcagcacct cccacacctg
    48481 cttgagcgcg tccggcccgc tcagcccggt cgggacgggc gcgtggaaca acacgtccgg
    48541 gtgcacgacc tcgtcgatgg tcttgctgat gagcgccagg tcgtgggtgt tcagcgcgtc
    48601 gtggaaccgg ccgaacaccg cctggttcct ggtttcctgg tcggtcggca tggtgctggt
    48661 cctcacttcc ggtagttctg gccgggagga cgccccggca gcggcttgcc gatcagcgcg
    48721 accggcacga acagactgaa atggccgatc gccacggtga gcgtccaaag tgcctcgtcg
    48781 ctgtagacgg cggacgccct ggcgaacagc tcgtcggaca cgcgctcccc ggacgggttc
    48841 ggcgtcatca cggcctccac cagctccagc gcgatccgtt cgtcggcggt gaagtacggc
    48901 gcgtccgccc aggtcgccac ggcggtgatg cgccgctccg gttccccggc cgtgcgcagc
    48961 tcgtcggtca cccggacggt cagataggtg ctgcccgcca gctgcgcggc ccgcagctgc
    49021 accaggctga tcgtggtccg cgggatcggg ccgtcgccga gcgccttgac cagtgcgccg
    49081 gacagcgcgg tcagttcggg gaacagctcg gcgggatcgg gcaggcgtga cttcagctcg
    49141 tccggctcga tcgtgcttgt catggggatt ccttccgtcg cgggtccttc ctcccttcga
    49201 caactcagcc gccgcgaatg tgaggtgggc cgccgttgtc acagttcggc gtgccacccg
    49261 gtcgtagtga tgacgacatc acgaacgaag gagcagcatg accaccacga ccgatcccgg
    49321 cctgagcgag cggcaccagc tggtcaacgt cgcctaccgg ctgctcggct cgctggcgga
    49381 ggccgaggac gtggtgcagg aggcctacgc ccgctggtac gcgctgcccg ccgcgcagcg
    49441 ggcggcgatc gaggcgcccg gcggctggct gacgaaggtc gccgcgcgcc tctgcctcaa
    49501 cctgctcggc tcggcgcggg tgcgccggga acgctacgtg ggtgactggc tgccggagcc
    49561 gctgcccgaa ccgggcggcg acccggccga ccgggtggcg ctcgacgagt cggtcaccat
    49621 ggccttcctc gtggtgctcg actcgatgac cccggccgag cgggtcgcgt tcgtgctcca
    49681 cgacgtcttc cgctacccgt tcaccgaagt ggccgagatc ctcggccggt caccggcggc
    49741 gtgccgccag ctggccacgt cggcacgccg tcgcgtccgc accgcgcgga agcccgcgcc
    49801 cgccgcccgt caggcggaag tcgtccggaa gttcaagcgg gcatgggaag ccggggacat
    49861 cggcgcgctg gtcggcctgc tcgacccggg ggtgaccgcc gtcggcgacg gcggtggccg
    49921 ggccggcacc cggcggagcc cggtcgaagg cgccgaggag ctggtgcgtt acctgctcgc
    49981 catcgccgag cggctcagcg cgctggaact ggcggagtgc acggtcaacg ggcagcccgg
    50041 cctcctcgcg cgggagaacg gcgtgacggt gacggtgtac gcgttcgatc tcgacgggga
    50101 gcggatcagg aacatctggg cggtgcggaa tccggagaag ctccgcctgt ggaacacccg
    50161 acgcgcggga gcggcgtgaa gcgctcagcg cgacacccga gtgctcagct cggcacggtt
    50221 cgcaggctgg acggggtcat cgacagctcc cgcgtgaaag cgtgcgtgaa ggcggcgggc
    50281 gtcgcgtagc cgaggcgggc ggcgacctcg ctcaccgtct cgtcacgcag cagcggaacg
    50341 gcggcgagca gtcccgcccg gcgacgccat gccgacggcc cggtgcccac ttcgcgctgg
    50401 aacaaccggg tcagcgaccg ctcgctgagc agcgccgcgc gtgcccagtc cgcgttcgtg
    50461 acgctcacgt gcgggtggag caggaactcg cggcacagcg accgcagcac cggcgacgtc
    50521 ggcagcggga cgtgcagcgg aagcggcgtg agcgtggcga gttcgtgcag cagcaggtcg
    50581 atcagcgcac cgtcccttcc ggacacgcga tagcccaccg gcagttcggc ggcggcgagc
    50641 agcagttccc gcagcagcgg gcccacctcg acgacctcgc acgagtccgg ccaccacggc
    50701 accgcggcgg gctcgacgta gaggctcgcc gtccggaccc cgtccatcat cacgcggtgc
    50761 cgcgtgcgcg ccgggatcat caccgcccgc tcacgcggaa tggtccaggt accgcggtcg
    50821 gtgtcggcga ccatggtgcc gcgtgccgcg tacaggaact gcgcgcggcg gtgctcgtgc
    50881 cagtcgagca ggc
//
