LOCUS       NZ_LWAI01000066        17704 bp    DNA     linear   CON 07-APR-2024
DEFINITION  Priestia endophytica strain 3618_1C 3618_1C_contig_8, whole genome
            shotgun sequence.
ACCESSION   NZ_LWAI01000066
VERSION     NZ_LWAI01000066.1
KEYWORDS    WGS; RefSeq.
SOURCE      Priestia endophytica
  ORGANISM  Priestia endophytica
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
REFERENCE   1  (bases 1 to 27692)
  AUTHORS   Lekota,K.E., Mafofo,J., Rees,J., Muchadeyi,F.C., Madoroba,E. and Van
            Heerden,H.
  TITLE     Comparison of Bacillus endophyticus and B. anthracis characteristics
            using whole genome sequence analysis and microbiological analysis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27692)
  AUTHORS   Lekota,K.E., Mafofo,J., Rees,J., Muchadeyi,F.C., Madoroba,E. and Van
            Heerden,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2016) Biotechnology Platform, Agricultural
            Research Council, 100 Soutpan Road, Pretoria, Gauteng 0110, South
            Africa
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-MAY-2015
            Assembly Method                   :: CLC Genomics workbench v. 7.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 330.0x
            Sequencing Technology             :: Illumina HiScan SQ
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003269975.1-RS_2024_04_07
            Annotation Date                   :: 04/07/2024 05:04:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,413
            CDSs (total)                      :: 5,355
            Genes (coding)                    :: 5,223
            CDSs (with protein)               :: 5,223
            Genes (RNA)                       :: 58
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 44 of 132
            Pseudo Genes (incomplete)         :: 88 of 132
            Pseudo Genes (internal stop)      :: 43 of 132
            Pseudo Genes (multiple problems)  :: 35 of 132
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:25:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9988
            Orig. end                         :: 27692
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LWAI01000066.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..17704
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..17704
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..17704
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11110](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11110
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            547..897
                     /locus_tag="A4U60_RS26735"
                     /old_locus_tag="A4U60_26535"
     CDS             547..897
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019392422.1"
                     /locus_tag="A4U60_RS26735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26535"
                     /product="DUF5412 domain-containing protein"
                     /protein_id="WP_242447778.1"
                     /transl_table=11
                     /translation="MKVYFFGFLLFIGFIGYGVYWAFFDMDRLPTGDYLTEEKSPDGVY
                     TLKAYITNGGATTSFAVRGELVFNNKGKKTKNIYWNYREETADIKWIDNNTVAINGHIL
                     NVPDDKFDFRNQ"
     misc_feature    complement(579..596)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 25.17"
                     /tool="antismash"
     gene            complement(1156..1710)
                     /locus_tag="A4U60_RS26740"
                     /old_locus_tag="A4U60_26540"
     CDS             complement(1156..1710)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024803.4"
                     /locus_tag="A4U60_RS26740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26540"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_172463582.1"
                     /transl_table=11
                     /translation="MENSTLDQEKAYWTREVAELLDIKEGTVRKYARLMEENGYNFHRN
                     EHDQRGFFERDILLMKRIKALSKTKGVTLEDAVNTVTKGVMVAERDSITPAAMNLQEEL
                     ERSIERHKQTMEAFIQLKNENTEMKELLMNLSEQMKQQQTYIENSLEKRDQVLLESIQK
                     TLEQRREEENTGWFKKLFKSK"
     misc_feature    2235..2246
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.41"
                     /tool="antismash"
     misc_feature    2932..2952
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.21"
                     /tool="antismash"
     misc_feature    3316..3329
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.68"
                     /tool="antismash"
     misc_feature    3494..3507
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     strong, score: 26.74"
                     /tool="antismash"
     gene            3568..4752
                     /locus_tag="A4U60_RS26745"
                     /old_locus_tag="A4U60_26545"
     CDS             3568..4752
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019392424.1"
                     /locus_tag="A4U60_RS26745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26545"
                     /product="ParM/StbA family protein"
                     /protein_id="WP_113754915.1"
                     /transl_table=11
                     /translation="MKIILANDIGNDKMKILEPGIEKVVKIPSAYKRINRKPSVHENDV
                     KKNIVNLIDQLLVHISSSSIRRDGLYMIGERAIQTTEGVSNMDIAVHEKHSSDLPLINT
                     LGYAAARAVQKQYEEEGELPQSLKVEVGMSSAIPASQHNVETAKQLEERFMGTSHVVIV
                     YVGQEQVTVELNFSQVKVTKEGIPALYAIFEAPNDMFQEFCKEYGMKGIDGSYFMNSKI
                     MHIDIGSGTTEYIYSVGVNPQPEQCTGERRGVGHAVEEAIQLMKEERKGLNINRQQFAK
                     YIERPDEYPKDHDLAVHYLREARINQVDFILEDVERKYTTTLSSEPEYLACYGGGSIEF
                     KEDMYKYLKELADSVDAKVLWIPAQYAVDMNVKGLDILNRNMLFTEEYEETVVM"
     gene            4757..5161
                     /locus_tag="A4U60_RS26750"
                     /old_locus_tag="A4U60_26550"
     CDS             4757..5161
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019392425.1"
                     /locus_tag="A4U60_RS26750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26550"
                     /product="hypothetical protein"
                     /protein_id="WP_061803087.1"
                     /transl_table=11
                     /translation="MTNEKKRKTQYNWKFKSNETDEFYEWFENQDNIALSLRKIVYHMI
                     ELYGTESVLNHHVDKEMSRDMFILEALRGKEALVVKESILSGGSPGENSFMPEKPSASV
                     QDERRVSEEPNKPEAKSKVNYQKVNPKSIF"
     gene            5658..5780
                     /locus_tag="A4U60_RS27880"
     CDS             5658..5780
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4U60_RS27880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_277949903.1"
                     /transl_table=11
                     /translation="MEDQSDTEKAETEAQILLKEDKKKLNEMLKKFKEKEQDFH"
     misc_feature    complement(5808..5822)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            5993..6175
                     /locus_tag="A4U60_RS26755"
                     /old_locus_tag="A4U60_26555"
     CDS             5993..6175
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4U60_RS26755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4U60_26555"
                     /product="hypothetical protein"
                     /protein_id="WP_113754916.1"
                     /transl_table=11
                     /translation="MGIKVRNINPVVVKKIEKMAREKGIQRQEFLKKQIETLTFFRKQT
                     TRKHHLEKLIDKNIQ"
     gene            6311..6973
                     /locus_tag="A4U60_RS26760"
                     /old_locus_tag="A4U60_26560"
     CDS             6311..6973
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019392814.1"
                     /locus_tag="A4U60_RS26760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26560"
                     /product="hypothetical protein"
                     /protein_id="WP_113754917.1"
                     /transl_table=11
                     /translation="MAQKISLTGRPTSSIQDYGKYLAFDMEEKGSPNAPKGIPFQSNAI
                     TYTVVLSLKQFNKLNINQEEFSQRRFLVQGEPCLDIPFEQCTGEIGVICMQIQEIEDKG
                     KEKKQTKQIPKKGSRAKKQEESKPLEESKQEQEKKPLLVPKGTKDWMSLDDIKVPETFL
                     QFTPGIAKQKAVEESIEKNGTVDKPIIINPETHELVDSYSRYYVAKQKKLDRVPVHY"
     gene            7333..7491
                     /locus_tag="A4U60_RS26765"
                     /old_locus_tag="A4U60_26565"
     CDS             7333..7491
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019392430.1"
                     /locus_tag="A4U60_RS26765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26565"
                     /product="DUF1540 domain-containing protein"
                     /protein_id="WP_113754918.1"
                     /transl_table=11
                     /translation="MATGVLCEVNTCKNWKNGNKCTADFIYVVNFDGKQTSEAEETGCK
                     TFEPSTS"
     gene            7564..7719
                     /locus_tag="A4U60_RS26770"
                     /old_locus_tag="A4U60_26570"
     CDS             7564..7719
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003204488.1"
                     /locus_tag="A4U60_RS26770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26570"
                     /product="DUF1540 domain-containing protein"
                     /protein_id="WP_111925597.1"
                     /transl_table=11
                     /translation="MAQDVLCEVNNCKYWGQGNKCQAEAIYVVSHKGKQASNSEETDCK
                     TFVPEA"
     misc_feature    7766..7781
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.44"
                     /tool="antismash"
     misc_feature    complement(7769..7784)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.8"
                     /tool="antismash"
     misc_feature    7772..7787
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.04"
                     /tool="antismash"
     misc_feature    7774..7788
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.98"
                     /tool="antismash"
     gene            8065..8913
                     /locus_tag="A4U60_RS26775"
                     /old_locus_tag="A4U60_26575"
     CDS             8065..8913
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019392432.1"
                     /locus_tag="A4U60_RS26775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26575"
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_113754919.1"
                     /sec_met_domain="PEP_mutase (E-value: 6.3e-78, bitscore:
                     252.4, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTQNRFKKFQKFKELHQQSSTFVLPNAWDAMSARTYQEEGFQAV
                     GTTSAGISISLGYPDGENIPFEMMLSALKIIVNSVNVPVSADIEGGYGLIGEELTEKIK
                     QIILTGVVAINIEDGTGDPHHPLTDLSLQLEKIAIIREISQSMDMPLFINARTDLYWLN
                     IGNPNERLKSTINRTRAYQEAGADCVFIPGLRCIDSIRTLRQEISCPINLLAELGSPSL
                     EELSNIGIERVSCGSAPFRATVTLLKKISRHIMKDSNLEYMNEGTILYKELANKMEFNQ
                     N"
     gene            complement(8981..9451)
                     /locus_tag="A4U60_RS26780"
                     /old_locus_tag="A4U60_26580"
     CDS             complement(8981..9451)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092367.1"
                     /locus_tag="A4U60_RS26780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26580"
                     /product="DinB family protein"
                     /protein_id="WP_113754920.1"
                     /transl_table=11
                     /translation="MNTIDFLEFNLKETRRRSEIVWNAIPEDKLNWKPDEDAMTCIEMV
                     RHVLEAEHYYCLAIKNRASIENFDSPFDKRPFISIKDELDFAEPYHREFINSLQFFSSG
                     DLENIKIDRSDEGYIRSLGDMLMRIAYHEAVHTGQLLDYLRTMDVPRPKIWD"
     misc_feature    9439..9457
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.72"
                     /tool="antismash"
     misc_feature    9503..9519
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.37"
                     /tool="antismash"
     misc_feature    complement(9783..9797)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.13"
                     /tool="antismash"
     aSDomain        10001..10270
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_A4U60_RS26785_Pantocin_Microcin_RRE.1
                     "
                     /evalue="1.40E-20"
                     /identifier="RREFam017.1"
                     /label="A4U60_RS26785"
                     /locus_tag="A4U60_RS26785"
                     /protein_end="90"
                     /protein_start="0"
                     /score="64.2"
                     /tool="antismash"
                     /translation="MIKPKFKETIPVFFVNNEIHIGEEDGVAGVIEDPNGSIQYLISLI
                     DGENTIETIIEKVILKYPDITAEEVQGAIQSLNEEKYLEDNAITP"
     gene            10001..11110
                     /locus_tag="A4U60_RS26785"
                     /old_locus_tag="A4U60_26585"
     CDS             10001..11110
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802791.1"
                     /locus_tag="A4U60_RS26785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26585"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_242447777.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 1.4e-20,
                     bitscore: 64.2, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 1.7e-45, bitscore: 146.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKPKFKETIPVFFVNNEIHIGEEDGVAGVIEDPNGSIQYLISLI
                     DGENTIETIIEKVILKYPDITAEEVQGAIQSLNEEKYLEDNAITPTLMGEYEKERYKAN
                     LNFFSLFTSLEDSKFDIQERVMNTKIALLGVGGLGSQILYHLAALGFHNITALDFDTLE
                     LSNFNRQLLYSEENIDELKIEMAKKRISKFNPNVKLDIVNKRIGCAEDVMNHIQDSEYV
                     ICVADKPTLYIQDWVNEAVVKLDKPLVSGGVLNTRGRFFSIIPGKTGCVECHKHTVIAS
                     DEKVNDQLNNMNQVNFQRNNAAISPNVAMLAGAMVNEFLGLVTGIKHPTSLGKMMELNF
                     LTYQTYSISEWEKQEECSVCNSTSVTATS"
     gene            11134..12366
                     /locus_tag="A4U60_RS26790"
                     /old_locus_tag="A4U60_26590"
     CDS             11134..12366
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="A4U60_RS26790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26590"
                     /product="MFS transporter"
                     /protein_id="WP_172460162.1"
                     /transl_table=11
                     /translation="MKSYQVLKNRNFLWLFLSATTSKLGTSVFQVALPLLVYELTRSPS
                     LMALTFVLEITPQVLFSLMGGAFADRISKRNILLLGEIISSVLIVIIPLASLANSLEVW
                     IVYVVAFCLSSVSAFYHPSFESVVPEILKGENLIQGNSLFKLSETITTFIGPSIAGVLI
                     AVIGIHNLLYLNFVTYLLSAIFIGFINEKYKSSSSNSSIISSIKEGINYVLKTKKILIG
                     TIFIFMVNLGYGAMESLFMFYLKDSLKLSSQYVGLIFSLQTLGSFLAIYLANKLNKMPR
                     GNIIIIAGLIIGIGQVALTMSQGIVILLIMCRIVIIGSVTILSINWFTLRQEVVPPSLL
                     GRVISSTRMLAFLALPFGGMVSGIIAEYMDVALIFTFAGVLTFILSLIGLKTALFQRQQ
                     HVPREVTSKTD"
     gene            12766..13656
                     /locus_tag="A4U60_RS26795"
                     /old_locus_tag="A4U60_26595"
     CDS             12766..13656
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019392434.1"
                     /locus_tag="A4U60_RS26795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26595"
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="WP_113754922.1"
                     /transl_table=11
                     /translation="MTKRLDLRVDFAFKSLFGTHGNESILAAFLNAALRLQEEKKITTV
                     HLLDPHFNKENQEDKRSILDVHAQLEDGTRINIEIQLNNKHDMEKRTLYYWSKMYSSQM
                     KEGMDYGELCQTITINIVNFRYLSHINHYHSIFQLYEREERLLLTDMLEIHFMELPKLL
                     IKWRRKEVDPREDQLVRWLLLLEASEDEEITQVLEEIAMQEDQVLKKAIDEWERVSQDP
                     EVLLAYEARRKALLDEKSALKRAESRGKEKGREEGRKETIKNMALGMIHKGIDNETISD
                     LTGLTQEEINNLRHQ"
     gene            13925..14413
                     /locus_tag="A4U60_RS26800"
                     /old_locus_tag="A4U60_26600"
     CDS             13925..14413
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003253368.1"
                     /locus_tag="A4U60_RS26800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26600"
                     /product="DUF2975 domain-containing protein"
                     /protein_id="WP_113754923.1"
                     /transl_table=11
                     /translation="MKQSSTLFLKITVFIIGTPVLALCIFWLPWMATKDAAAHPETAYL
                     QYPFLIGAYITVTPFFIALYQSLKLLSYIDRNKVFSELSVRALKYIKYCAITISTLIVV
                     GIISGFILIAGEGEDITGFISLGLMLTFASMVIAVFAAVLQRLLQKVIDIKSENDLIV"
     gene            14424..14645
                     /locus_tag="A4U60_RS26805"
                     /old_locus_tag="A4U60_26605"
     CDS             14424..14645
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003181209.1"
                     /locus_tag="A4U60_RS26805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26605"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_113754924.1"
                     /transl_table=11
                     /translation="MAIIINIDVMLAKRKMSVTELSERGGITMDNLSILKNGKAKAVRL
                     STLEVVCKALECQPGDILEYKSDEDTQE"
     misc_feature    complement(14431..14444)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.68"
                     /tool="antismash"
     gene            complement(14728..15141)
                     /locus_tag="A4U60_RS26810"
                     /old_locus_tag="A4U60_26610"
     CDS             complement(14728..15141)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019392436.1"
                     /locus_tag="A4U60_RS26810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26610"
                     /product="YbaN family protein"
                     /protein_id="WP_225985429.1"
                     /transl_table=11
                     /translation="MIIIKNIKSILFFLLGFIALGIGIAGIILPVLPGGPFLLFASFCF
                     AKSSKRIENWFQGTSFYKKYVERFYKKTGMTRKEKIRINLIADAFIIFSVFYVDILPIQ
                     ILLVVLALYKHYYFIKKIKTIKLKQDEIVKEFV"
     gene            complement(15537..16415)
                     /locus_tag="A4U60_RS26815"
                     /old_locus_tag="A4U60_26615"
     CDS             complement(15537..16415)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017358629.1"
                     /locus_tag="A4U60_RS26815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26615"
                     /product="aldose 1-epimerase family protein"
                     /protein_id="WP_113754925.1"
                     /transl_table=11
                     /translation="MIVIENDWLKVGIEGKGAEVRKVEHKKNELDYMWTGDSAYWGRVS
                     PVLFPIVGRLKGDQYQIDGQTYEMSQHGFLRDVEFNIDDHTTEQVSFVFESAGRFLDVY
                     PYEFKATIYYILNKDSLIVRWKIENDSKEEMYFSIGAHPAFRIPLLENEMIEDYRLELT
                     PATNKTVLNYELKDSLIHEKGTANDIAPISLTASLFKNDAVIYSNIDSIILSSNKSSHG
                     VEVAFNGFPFVGIWSKYNETDGTMAPFVCIEPWYGIADTHDTSGNMKDKFGVNRLEVGK
                     TFQAEYEMKFK"
     gene            complement(16619..>16984)
                     /locus_tag="A4U60_RS26820"
                     /old_locus_tag="A4U60_26620"
                     /pseudo=""
     CDS             complement(16619..>16984)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019392797.1"
                     /locus_tag="A4U60_RS26820"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="A4U60_26620"
                     /product="recombinase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="LSLEKVDIIVLDMRLLDTTQYKDSLGTFIADLVLQILSWVAKEER
                     GRIRKHQREGIDAALKSGIYFGRPKAQVN"
     gene            17277..>17704
                     /locus_tag="A4U60_RS26825"
                     /old_locus_tag="A4U60_26625"
     CDS             17277..>17704
                     /EC_number="2.-.-.-"
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /GO_function="GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019392439.1"
                     /locus_tag="A4U60_RS26825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_26625"
                     /product="L,D-transpeptidase"
                     /protein_id="WP_113754926.1"
                     /transl_table=11
                     /translation="MKKILIKTMTVLALLVFLVGGMTTGKTDAASNTANQDLIIINKYY
                     NKLAYYHNGYLEMVVPVATGKTWDKTPVGFFKVVNKIKNRPYYTGKIPGGDPRNPLGKR
                     WLGINANGTYGDTYGIHGNNNESSIGKYVSLGCVRMHNA"
ORIGIN
        1 tcaaactttt aaagatattt ttaaagactc tttaagagag ctttatttac gcattcgttt
       61 ggcttctaaa aaagtatgtc aatctttatc tataactctt tcaaagaagg atattcattc
      121 catagcttat gaatctattc aaattctttt tacatacata aaaacgcgtt ctatgagttt
      181 tgagaaacaa tgtaaattag tgtatagtat cgctttaaat aagtttaatg atttagcaca
      241 aacagaagat caaaataaaa gcctagatcc tgtaacatta ccacgtaaga ttgttcgtaa
      301 agaaatgtta cctgattggt tccaggagca acaaaagaaa gaagctttag cagaaaaaga
      361 atcacaagcg caagacatgt atgaaatgtc atcagaagat gaaatagcaa aaatgaaagc
      421 cattttagcg ttctatactt aactaaagca ataggttatc ccccctacta catacctgct
      481 ttacctaagg aggattctgt gagtactgat ttaataaata gtaagagaaa agtctgtaaa
      541 aagagattga aagtatattt ctttggtttc ctattgttta ttggctttat aggatatgga
      601 gtatactggg cattttttga tatggataga ttgcccacag gagattatct cacagaggaa
      661 aagtctcctg atggagtgta tactttaaaa gcatatataa caaatggagg cgccacaact
      721 tcatttgctg tacgtggtga attagtattt aacaataaag gcaaaaagac aaaaaatatt
      781 tactggaatt atcgcgagga aactgcggat attaaatgga tagataacaa cacagtagcc
      841 attaatggac atatacttaa tgttcctgat gataaatttg attttagaaa tcaataactt
      901 actttgggtt gaagatgaaa aagtgagtta taaggatgct tagctaccta ttcccttttt
      961 tgtctcatac taataaagca gcgaaaaggc ataaaaaatc ttaattgttt ctttaagatt
     1021 tctatgcctt ttatataaac tattaaagta agcaatcata ttatttaaat attgaggaaa
     1081 gactaaccta ttatatgtaa gtgcgaaaat agcctcctca tactttataa gtttccataa
     1141 ggaaaaagta aatccttatt tagacttgaa taatttttta aaccatccag tattctcttc
     1201 ttctcttctc tgttctaaag tcttctggat agattctaac aaaacttgat cccgtttctc
     1261 taaactattc tcaatatatg tttgttgctg tttcatctgt tctgataagt tcattaataa
     1321 ttccttcatc tctgtatttt cattttttag ttgaataaaa gcttccatag tttgtttatg
     1381 acgttctata gaacgctcta attcctcttg aagattcatg gcggcaggcg taatagaatc
     1441 tctttctgct accataactc cttttgtaac agtatttaca gcatcttcta gcgtcacacc
     1501 ttttgttttg ctaagagctt tgatgcgttt cataagcaaa atatctcttt cgaaaaaacc
     1561 acgctgatca tgctcgtttc tatgaaaatt atacccgttt tcctccataa gacgagcgta
     1621 cttacgcact gttccctctt ttatatctaa taattcggct acttctcttg tccagtaagc
     1681 tttttcttga tcaagtgtac tgttttccat agtatattcc tccattttta taatgtaatt
     1741 caattattaa aaatagttta tttttcttag ttttttaatg tttgaaatgt gttcaatgat
     1801 tctatttata acgctgtagg aaacgttata aataagtgat gaaggttgta acgggtagcg
     1861 tcacaagaga tttttgtgtt gttagaaacc ctttaatatc aatgtttata agctcttgta
     1921 gcgacatgag aaatataacg ctacttaaaa atgatcaaaa tggctatttt atagatgctt
     1981 tttgaaaaat acacgttata tagttttaca taacgtgttt tatgatacaa caatactttc
     2041 tatcagtttt aattctggac gctctaaata acacctttgt ctaagtttgg aactatgctt
     2101 acaaaaataa tagatcagag attataatta taaacgtttt aattaaattt gaacataaac
     2161 acaatgtatg gatagatgga aaataattaa atttatatga gttaggatat acttcactta
     2221 tttataacgt tgtagaaaac gttataaata agtggttaag gttataacgg atagcgtcac
     2281 aaaagaaaat atattgtaga aaactcttta gtatcaacgt gtataagctt ttataacgtt
     2341 atgagaaata taatgctatt taaaattgat taaaatagct atttcataga ggttcttgag
     2401 aaaatacgcg ttatgtagtt ttgtataacg tgttttgtga tgcaacaaga ctttctatta
     2461 attttaattc tggacgatct gaataacacc tttgtctaag tttgtagcta taattacaaa
     2521 aatgatatat cagagctcgt ttttataaat gttttaatta aacttgaaca tagacacaat
     2581 gtatgaatag aggaagataa ttaaatttat ataaattagg atatacttta cttacttgtt
     2641 tataacgctg taggaaacgt tataaacaag taaggcagac tataacgggt ggcgtcacaa
     2701 aagatttttg tattatgaga aaccctttag tatcaatatt tataagcttt tatggcgtta
     2761 cgggagatat aacgccactt aaaatagcta tttcatagag ggttttgaaa aaatatgggt
     2821 tgtatagttt tgtataacgt gttttgtgat gcaacaagac tttctaccaa ttttaattct
     2881 ggatgatcta aatagcacct ttgtctaagt ttgtaactat atttataaaa ataatatatc
     2941 aaaggttatt tttgtaaatg ttttaattaa atttgaatat aaacacaatg tatggataga
     3001 taaaagataa ttaaatttat ataagctagg atatacttta cttgcttata tataacgctg
     3061 taggaaacgt tatatacaag taaggcagac tataacgggt agcgttataa aagattttgt
     3121 gttatgaaaa accctttagt atcaatgttt ataagccctt atagcgttat gagagatata
     3181 acgcgactga aaatcaatta aaatagctat tttatagagt cttctggaaa aatatacgtt
     3241 atgtagtttt gtataacata ttttgcatta tttagataat aagttagtat tttaatttct
     3301 cttttagtta atttatataa ttattatata ttgaagattt atttttatgt aaaaagaagt
     3361 gtttgatgta tagatataac gtattttaat taaatttata taataaaaac ctaatttatt
     3421 atataaatta tatataaaat aattttgatt tattttatcg ttagttttag atttcttttt
     3481 ggttatcaaa ttatataatt attattaact tattatataa ttcatgataa aatcgatata
     3541 ggataacaaa aaggagtgga tttaataatg aaaataatcc ttgcgaatga tattggaaac
     3601 gacaaaatga agattcttga accaggcata gaaaaagtcg tcaagattcc aagtgcttat
     3661 aaacgaatta accgaaaacc ttccgttcat gaaaatgatg taaagaaaaa tatagttaat
     3721 cttatcgatc aattacttgt acatatttca agctcatcca ttcgtcgtga tggcctatat
     3781 atgattggag aacgagcaat tcaaaccaca gaaggcgtaa gtaacatgga tatcgccgtt
     3841 catgaaaagc atagtagtga tttaccttta attaatacgt taggttatgc tgcagcaaga
     3901 gccgtacaga aacaatatga agaagaagga gaacttcctc aatcattaaa agtcgaagtc
     3961 ggcatgagta gtgcgattcc agcgagtcaa cataatgtgg agacagcgaa acaattagaa
     4021 gaacgtttca tgggtacttc tcatgtggtt attgtgtatg ttggtcaaga gcaagtaacg
     4081 gtagagctaa acttttcaca agtaaaggtg acgaaagaag ggattccagc gttatacgct
     4141 atctttgaag caccaaatga tatgtttcaa gagttttgta aagaatatgg aatgaagggt
     4201 attgatggtt cttattttat gaactcgaag attatgcata ttgatatcgg aagtggcaca
     4261 accgagtata tttattctgt aggcgtgaat ccacaaccag aacaatgtac aggcgaaaga
     4321 cgaggagtag ggcatgcggt cgaagaagcg attcaattga tgaaagaaga acgtaaaggc
     4381 cttaatatta atcgtcagca atttgcgaaa tacattgagc gaccagatga gtatccaaaa
     4441 gatcatgact tagctgttca ttacttgcgt gaggctcgta tcaatcaagt ggatttcatc
     4501 ctagaagatg tagaacgtaa atatacgaca acactctcta gtgaaccgga atatctagct
     4561 tgctatggtg gaggatctat tgagtttaaa gaagatatgt ataagtacct gaaagaattg
     4621 gcggattctg tggatgcaaa agtcctttgg atcccagcac aatatgcggt agatatgaat
     4681 gtgaaaggat tagatatttt aaatcgcaac atgctattta cagaagaata tgaagaaact
     4741 gtggtgatgt aaaggtatga cgaatgaaaa aaagagaaaa acacagtaca actggaagtt
     4801 taaaagcaac gaaaccgatg agttttatga atggtttgaa aatcaagata acattgcact
     4861 gtctttacgt aaaattgtgt accatatgat tgaactatat gggacggaga gcgtcttaaa
     4921 tcatcatgtc gataaagaaa tgagtcgaga tatgttcatt ttagaagccc ttagaggaaa
     4981 agaggcttta gtggtaaaag agagtatcct ttcaggagga tctccaggtg aaaattcatt
     5041 tatgcctgag aagccgtctg cctctgtaca agatgaacgt cgtgtaagtg aagaaccgaa
     5101 taaaccagaa gctaaaagta aagttaatta tcaaaaggtt aacccgaaat caattttttg
     5161 atgactttta aggaatatag tacagccctc acatcaggtg agggctattt tttataagga
     5221 gataagatga aaaagttgaa tgaataaaat gaagaagaat tgacttttaa gtctagaaaa
     5281 agtccattca agggtagact tacggattaa agtcttgtat caggtacgtg gtaagggcga
     5341 aacaattatc tttaaattag gaggccttag cgcttgcttt atatcaaaaa ttgatggaag
     5401 aagaaagcgt gaatgttacg ggaagagaag tgaaaacaga ggaggaagag ccacaagata
     5461 aactcgttca gacgacctct tccggtcaaa caaaaatgcc tacaagtacg gaaaattcat
     5521 cctagaatag gcaacttaca gagtattagt gatcgacatt cagccaaaag aaaatgaaat
     5581 cctatgaaaa tgtcattata gttgagatga aaaattagag agctttacga aaagaaatag
     5641 gggagttaaa agccgatatg gaggatcaaa gtgatacaga aaaagctgaa acagaagctc
     5701 aaattttgct aaaagaagat aagaaaaagt tgaatgaaat gctcaaaaaa tttaaagaaa
     5761 aagagcaaga ttttcactaa agttgaaaaa agacaggtcg accgtatatc gacactaagg
     5821 atttttgata tcgatattgt atcaacagta ggtcggcact tcgggctttt ccttgatatc
     5881 actgttttac taggctttgc ctagtctatc accccatgtg atagcaaaaa ccccttatgc
     5941 tcttctatct ttttgaatgt agagcactaa attttgagag aagatgaatg aagtggggat
     6001 taaagtaaga aatataaatc cagttgtggt gaaaaagatt gagaaaatgg caagagaaaa
     6061 aggaatacaa cgacaagaat ttttgaaaaa acagattgaa actctgactt tttttcgtaa
     6121 acaaacgact cgaaaacatc atctagaaaa gctcattgat aagaacatac agtgaaaaaa
     6181 ttaataatgt agaaatttaa taaaaacatg ggataatcac ttttttctgt tgttttttgg
     6241 actttacccc tacccaagta tatataaggg tatatatact agaaatatag agggagaagg
     6301 agggagaacg atggctcaaa aaattagttt aactggccgt ccgactagct caattcaaga
     6361 ctatggtaag tacctagctt ttgatatgga ggagaaggga agtcctaatg cgcccaaagg
     6421 cattcctttt caaagtaatg caattacata caccgttgtg cttagtctaa aacaatttaa
     6481 taaattaaat ataaaccaag aggaattttc acaacgacgt ttccttgtcc aaggagagcc
     6541 ttgtttggat attccttttg agcaatgtac aggcgagatc ggtgtcatct gtatgcagat
     6601 acaagaaatt gaggacaaag ggaaagagaa aaaacaaaca aaacaaatac ccaaaaaggg
     6661 ttcaagggct aaaaaacaag aggaaagtaa acctctagaa gaaagtaaac aagagcaaga
     6721 gaaaaagcct cttcttgttc caaaggggac gaaggattgg atgtctttag atgatattaa
     6781 ggtcccagaa acctttcttc aatttacccc aggaattgcg aaacaaaagg ccgtagagga
     6841 aagcattgag aagaatggaa cggtggataa accgattatt attaatccag aaacacatga
     6901 actcgtcgat agttatagtc gttattatgt cgccaaacag aagaaattag atcgtgttcc
     6961 tgtacattat tagaagaagt ttttatattt attgagtgca taaaacattt ggtttttatg
     7021 cgctcttttt gtgttggaga atgaaggaaa gattacgaga ttttttgggg gacaagaagt
     7081 taggaaatgt tcaacttctc ctaacgaaca tcatgttaac taagtttcta tatagggtac
     7141 agtaaaaaaa cagaaaaact tgctgtgggg gtagagagtt tttctattac gtatcttgag
     7201 tagttcgctt agaaggccac agagtttcca tttatataaa tcaagttctt atattaaaaa
     7261 ggttttttgt taggtgagta gaaataactt ttaatagaca aattatatga gatttgaagg
     7321 ggggtgaata ctatggcaac tggtgtattg tgcgaggtaa atacctgtaa gaattggaag
     7381 aatggaaaca aatgtactgc tgatttcatt tatgttgtca attttgatgg aaaacaaaca
     7441 tctgaagccg aagaaacagg ctgtaaaact tttgaacctt ctacttcata aaaaaacgat
     7501 ataaaagatc agcatcaaca acccataatt tgttaatcat aacaaaatag gaggtgtgat
     7561 attatggctc aagatgttct ttgtgaagta aacaactgta agtactgggg acaggggaat
     7621 aaatgtcagg ctgaagctat ttatgtagtt agtcataaag gcaaacaagc atccaacagt
     7681 gaagaaacgg attgcaaaac atttgtacca gaagcttaat caataagggt aaccatcttc
     7741 catatggttg ctcttattga ttattattga taataataat cattttcata cataattatt
     7801 tcatttttaa aattaaatcc tcggcttcct aactttctat attatctcct tttgaatgat
     7861 ggaaacagtc actatatcta tcccctgtgt tagctggttt tattttgaat aaactgtgct
     7921 aagagtgatt ttttatttta atgttataat aaaatccaga tttttaactc aatatgttaa
     7981 aaatctaata ttgtttcatt tcatcttgta attcttaata taacaatagg tactacatcc
     8041 aataacaagg gagagaaatt tttcatggat actcaaaatc gatttaaaaa gtttcagaag
     8101 tttaaagaac tccatcagca atcttctact tttgtattac ccaacgcatg ggacgctatg
     8161 agtgcgagaa cttatcagga ggaaggtttt caagcagtcg gtacgactag tgcaggaatt
     8221 tcaatctcgt taggctatcc ggatggagaa aatatacctt ttgaaatgat gttaagtgcc
     8281 ctcaagataa ttgttaactc cgtaaatgta cctgtaagtg cagatataga aggaggatat
     8341 gggttaattg gtgaagaatt aacggagaaa attaaacaga tcattctaac aggggtagta
     8401 gccattaaca ttgaggatgg aacaggagat cctcaccacc ctctaactga tctttcccta
     8461 cagttagaga aaatagcgat aattagggaa atctctcaat ctatggatat gccattattt
     8521 attaatgccc gaacagattt atattggcta aatattggta atcctaatga acgattaaaa
     8581 tccactatta ataggacaag agcttatcaa gaagcagggg ctgattgcgt atttatcccg
     8641 ggattgagat gtatagattc tattagaaca cttagacagg agatctcatg tcctattaat
     8701 ctactagctg aattaggttc tccatcatta gaagagttat ctaatattgg tattgagaga
     8761 gtaagctgtg gttctgctcc ctttagggca acggtaaccc tgttaaaaaa gattagtcga
     8821 cacattatga aggacagtaa ccttgaatac atgaatgagg gtacaatttt atacaaggaa
     8881 ttagctaata aaatggaatt taatcaaaat taaatataag ttatctaatg gttatgatat
     8941 aggaaaatct ctataactaa agttatagag attttcttgg tcaatcccaa attttaggtc
     9001 taggaacgtc cattgttcta aggtaatcta aaagttggcc agtatgaaca gcttcatgat
     9061 aagcaatacg cattaacata tcgcctaatg aacgtatgta tccctcatca gaacggtcga
     9121 tcttaatatt ctctaaatct ccactagaga aaaattgaag actatttata aattctctgt
     9181 gataaggttc cgcgaaatct aattcatctt taattgaaat aaaaggacgt ttatcaaagg
     9241 gggaatcaaa gttttcaata ctagccctat ttttaatagc taaacaataa taatgctctg
     9301 cttctagcac atgacgtacc atttctatac atgtcatggc atcttcatca ggcttccaat
     9361 taagtttgtc ctcaggaatt gcgttccaca caatttcact tcttcttctt gtttctttaa
     9421 gattaaactc tagaaaatca attgtattca ctatacttct ccctttccta gataatatgt
     9481 tcgtaattaa tattactaga aattttaaat taattacagg tgtggattac cataggatta
     9541 ctctttatat aaaaaatata tatttattta taaatacttt aataataggt agattgatta
     9601 caaattttaa cactttggtt ttgtattttt taaaaaagtt attgtaattt tctttttatc
     9661 ataataaaat gtacttaatt tcaaatatat ggaggtgtta catatgtcag ttaaagttaa
     9721 aaaaactagc aaaaaagctg ctgtccttta tagcttccca ggctaatgtc atttttagtc
     9781 taaatttaca gaataattag aattttaacc tttatgtatc ttcttaattt ggaggtgttt
     9841 catatgtcgg ttaaagttaa aaaaactagc aaaaaagctg ctgtccttta cagcttccca
     9901 ggctaataat tacttaatac tcaaacttca agaatgggga actatcatca gatagttcct
     9961 tatttattaa gtttataata gaatggagga taccaataaa atgattaaac ctaagtttaa
    10021 agaaacaatt ccagtctttt ttgtaaacaa tgaaatacat attggtgaag aagacggagt
    10081 agcaggtgtc attgaggatc caaatggcag tattcaatat cttatctcat taattgatgg
    10141 agaaaatact attgaaacta ttattgaaaa agttatttta aagtaccctg atatcacggc
    10201 tgaggaagta cagggtgcta ttcaatcatt aaatgaagaa aagtacttag aagacaatgc
    10261 tatcactcca actctaatgg gtgaatatga aaaagagcga tataaagcaa atcttaattt
    10321 cttctcattg tttacatctc tagaagacag caaatttgat attcaagaaa gggttatgaa
    10381 tactaaaatt gctttactag gtgtaggtgg attaggaagc caaattcttt atcacttagc
    10441 agcattaggg ttccataata taacggccct agattttgat actttggaat taagtaattt
    10501 taatcgtcag ttattatatt ctgaagaaaa catcgacgaa ttgaaaattg agatggcaaa
    10561 gaaaagaata tctaaattta atcctaatgt gaaattagat attgtaaaca agcgtatagg
    10621 gtgtgctgag gatgttatga atcatattca agatagcgaa tatgttattt gtgtagctga
    10681 caaacctact ctatatattc aggattgggt aaatgaggct gtagttaagt tagataaacc
    10741 tttagtttct ggaggagtac taaatactag aggaagattt ttttcaatta ttccaggaaa
    10801 aacaggctgt gtagaatgtc ataaacacac agttatagct agtgacgaga aagttaatga
    10861 tcagcttaat aatatgaatc aagtaaactt ccaaagaaat aatgcagcta ttagtcctaa
    10921 tgtagctatg ttagctggtg ctatggtcaa tgaattttta ggacttgtca caggaattaa
    10981 acatcctact tctctaggaa agatgatgga actgaatttc ctcacttatc aaacctattc
    11041 tatttctgaa tgggaaaaac aagaagagtg ttcagtttgc aactcaacat cagtaacagc
    11101 cacttcgtaa tctggtgtga gaagggagta cgtatgaaat cttatcaagt gttaaagaat
    11161 agaaatttct tatggttatt tttaagtgcc acaactagta agttgggcac ttccgttttt
    11221 caagtagctt tgcccttatt agtttatgaa ttaactagat cccctagttt aatggcctta
    11281 acatttgttc tcgaaataac ccctcaagtt ctctttagtt tgatgggggg agcttttgct
    11341 gatcgaataa gtaagagaaa cattttactt ctaggggaga ttatatctag tgttttaata
    11401 gtaatcatac cacttgcatc actggcaaat tctttagaag tatggatagt ttatgttgta
    11461 gctttttgtt tatcatcagt tagtgccttt tatcatccaa gttttgaatc tgtagtacca
    11521 gagattttaa aaggggaaaa cttaattcaa ggtaattcac tatttaaact atccgaaact
    11581 atcaccacgt ttataggccc ttctatagct ggtgtcttaa tagctgtaat tggaatacat
    11641 aatttattat atttaaattt tgttacctat cttctttccg ccatatttat cggctttata
    11701 aatgagaagt ataaaagtag ttcttcaaat tcttcgatca tttcttctat taaagaagga
    11761 attaactatg tccttaaaac gaagaagata ttaataggta ccatttttat ttttatggtc
    11821 aaccttggct atggtgcaat ggagtcttta ttcatgtttt atttaaagga ttctttaaaa
    11881 ttatcatcgc aatatgttgg gttaatattc tcattacaga cactaggctc atttttagca
    11941 atttatctag ctaataaatt aaataagatg cctagaggca atattattat tatagcaggg
    12001 ctgataatag gaataggaca ggtagcttta actatgtctc aaggaatcgt aattctcctt
    12061 attatgtgcc gaatagttat aattggttcc gtaaccattt tatctattaa ttggtttact
    12121 ttgcgacaag aggtagtccc accttctcta cttggacgcg ttattagttc tactcgcatg
    12181 ttggctttct tagcccttcc tttcggagga atggtatcag gtataattgc tgaatacatg
    12241 gatgtagctt tgatatttac tttcgctggg gtccttacct ttattttatc gctaatagga
    12301 cttaaaacgg cattatttca acggcaacaa catgtccctc gagaggtaac tagtaaaaca
    12361 gattgactat aatatttaat gtagaatttt cacttattga tacttagtcc aacttgttat
    12421 attattaatt agtatcaatt cttgaggttt gaatattaag taagcaaaca gccagtcatg
    12481 tcatctataa catgattggc tgtttgtctt tttggtgaag caaaaaaggg aaatgtgtat
    12541 agaagaattt tcatagtcat gtagttgttg tcataaagtc agaaatatta aaggatgttt
    12601 ataagcaatt atattggtct cgacatttct caataaccac cattttttaa atctatatat
    12661 cttaaatgcc tgtttgtgga ataaaccatc cgtaaaagta tacttaagag gaaaaagtaa
    12721 aactcatgtt atactaaaag aaaagaagaa atcacggagg atataatgac aaagcgatta
    12781 gatttacgtg tcgattttgc ctttaaatct ctttttggaa ctcatggaaa tgaatccatt
    12841 ttggctgctt ttttaaatgc agctctacgt ttacaagaag aaaagaaaat tacgaccgtt
    12901 cacttattag atccacattt taataaagaa aaccaggaag ataaacgatc cattcttgat
    12961 gttcatgctc aactagaaga tggaacccgt ataaacattg aaattcagct taataataaa
    13021 catgatatgg aaaaaagaac gctttactat tggtctaaga tgtatagcag tcagatgaag
    13081 gaaggaatgg actatggtga gctgtgccaa acgattacca ttaatattgt aaacttccgt
    13141 tacttatccc atatcaatca ctatcattca atctttcagt tatatgagcg tgaagaaaga
    13201 ttgttattaa cggacatgtt agaaattcat tttatggaac ttcctaaact tttgattaag
    13261 tggcgtagaa aagaagtcga tccacgagaa gatcaattgg taagatggtt attattgctt
    13321 gaagcatcgg aagatgaaga aatcactcaa gtactggagg agattgcgat gcaagaagat
    13381 caagtattaa agaaagcaat agatgaatgg gaacgtgtta gtcaagatcc agaagtttta
    13441 ctagcttatg aagcaagaag aaaggcttta ttggatgaaa aatctgcact gaaacgagct
    13501 gagagcagag gaaaagaaaa aggtagggaa gaaggaagaa aggaaaccat taaaaatatg
    13561 gctcttggta tgattcataa agggatagac aatgaaacga taagtgacct tacaggtctc
    13621 acccaagagg aaattaataa tctccgtcat caataagttt aactataaaa aggcagcgtt
    13681 ttcaagacgc tgcctttttg tatagagcca cctaagggag gaaggcttat tgagctaaaa
    13741 aagcaggtta gttgaacaaa ttatagagca tttcttttta aggagagatg ctttttatct
    13801 ttatgaaaaa ttaatataaa taatcattag caataaaaat taaataataa gcaataatta
    13861 tttaatgtaa atcaataaaa aaatgttaga atcacactag aaataaaata aatgaggtgt
    13921 ttttatgaaa caaagttcaa cactcttttt aaagataact gtttttatta tcggaactcc
    13981 agttcttgct ttgtgtatat tttggttgcc ttggatggcc actaaagatg cagcagcaca
    14041 tccagagact gcctacttgc agtatccctt tttgataggt gcgtatataa cggtaacacc
    14101 gttttttatt gctttgtatc agtccttaaa acttttaagc tatattgatc ggaataaagt
    14161 cttctcagaa ttatctgtta gagctttgaa gtatataaaa tactgtgcaa tcactatcag
    14221 taccttaatt gtagtaggga taatctccgg atttatattg attgcaggtg aaggtgaaga
    14281 cataacaggt tttataagct tgggattaat gctcactttt gcttcaatgg tgattgccgt
    14341 ctttgctgct gttcttcaaa ggcttttaca aaaagttatc gatataaaat ccgagaatga
    14401 cttaatagtc tgaggtggct aacatggcaa ttataataaa tatagatgtg atgttggcga
    14461 aaaggaaaat gagcgtaaca gaactttcgg agaggggtgg aatcacgatg gataatcttt
    14521 ctatattgaa aaatggaaag gcaaaagcag ttcgattatc cactttagag gtggtttgta
    14581 aggctttaga atgtcagcct ggtgatattt tagaatacaa aagtgatgaa gacacccaag
    14641 aataaaaatc gttatgattt aaatttcaga aactagatta ttttattaaa ataaaaagga
    14701 gagcattata aaactctcct gtacttctta tacaaactcc tttacaattt catcttgttt
    14761 taatttaata gtcttgattt tcttgataaa atagtaatgt ttgtagaggg caagtaccac
    14821 tagaaggatt tgaatcggaa ggatgtccac ataaaatacg gaaaatatga taaaagcatc
    14881 ggcaattaag ttaatacgaa ttttctcttt acgtgtcata cctgttttct tataaaatct
    14941 ttcaacatat tttttataga atgaggttcc ttgaaaccaa ttttcaattc gtttggaact
    15001 tttagcaaaa caaaaagaag cgaatagcaa gaatggccca cctggtagaa caggaagaat
    15061 aatccctgca atcccgattc ctaaggctat gaagccgaga agaaaaaata ggatactttt
    15121 tatatttttg atgataatca ccttactttt tattaatcta taggtctcgc cgataaaaat
    15181 acacctaatt tcatattagt atcgacacag gttctaatgc aagtattata gttgagaaat
    15241 agagaagtgt agttttattt aaatgactaa tttacgaagc agttccaaac agttattaat
    15301 ataagtagcg actaaattaa ccaaaaagcc atgttcagaa agtggtgatt ttcggaacat
    15361 agccttttgg gcaagtattt ggttttggca taaaaacttc aacatatcta taagtaatct
    15421 caaaaggaca tgcatgacta gtatgaaaga agaaaactta ctcaaatgga aacattatca
    15481 acctgagatt attttattaa ctgttatcat aacttgatgg ctgtgtgaca gtaagcctat
    15541 ttaaacttca tctcatactc agcctgaaat gtttttccaa cctcaagcct atttactcca
    15601 aatttatcct tcatgtttcc tgatgtatca tgtgtgtcgg caatgccgta ccaaggctca
    15661 atgcaaacaa atggagccat agtaccatct gtctcgttat attttgacca tatccccaca
    15721 aatgggaaac cattaaatgc tacttctact ccatgactcg atttattaga tgacagtatg
    15781 atgctatcaa tattactgta aataacagcg tcatttttaa atagagaagc agtaagcgaa
    15841 attggtgcaa tatcattagc agttcccttc tcatggataa gagaatcttt taactcataa
    15901 ttaagtacag tcttatttgt agcaggagtg agctctaatc tgtagtcctc aatcatttca
    15961 ttctccaaaa gtggaattct aaacgcagga tgtgcaccaa tagaaaaata catctcttcc
    16021 ttactatcat tttctatttt ccagcgaaca ataagggaat ccttgttaag tatataataa
    16081 atagtggctt tgaattcgta aggataaaca tctaggaaac gtccagcaga ctcaaataca
    16141 aaagaaacct gttctgttgt atgatcatct atattgaatt caacgtcacg caggaagcca
    16201 tgctgtgaca tctcataagt ctgaccatcg atttgatact gatctccctt taaacgtcct
    16261 actattggaa ataagactgg agagacgcgt ccccagtagg cactgtcccc tgtccacata
    16321 tagtctaact catttttctt atgttcaact ttacgtactt cggccccttt accttctata
    16381 cctaccttca accaatcatt ttcaattaca atcatcgtct tatatccctc atctctctgg
    16441 tctggaatgt cttattctca ttacactgaa agactcctct gtaatagata agagtccata
    16501 atttatctta aatcgtatta accttaaatg tctacatatt aacagatttc gcagatgctt
    16561 attagcaaac tacacaagaa attatggaac aaaggcctct ttgacgagtt ttttcctatt
    16621 atatatgatt tttgctaaaa gtatcctcat gttcctttac caatttataa aggattgtct
    16681 tttttacatt tgcctctttc atggcttaga tagctgtaat ctccttattt ctccatcaat
    16741 tataagcttc aataaattct caattaactt gtgccttagg acgtccaaaa tatataccac
    16801 tctttagtgc agcatcaatc ccctctcgct gatgtttccg aatacgacct cgttcctctt
    16861 tggccaccca agaaaggatt tggagaacta agtctgcaat aaaggttccc aaactatcct
    16921 tgtattgagt ggtatctaac aaccgcatat ctaaaactat aatgtccacc ttttctaatg
    16981 atagctatgg gtatgggatg aagaaatcta ggtaaaaaaa atccctactc aatctttata
    17041 aaaagaagga gcaaagtttt tacatttagc caatattaaa gtgaaaatgg ctgcaaaaaa
    17101 ataaataagg gtgatgagaa aatatcttct ctttataaaa ggcgctttat tgctacagaa
    17161 tattatagat aatttgtata atttgtgaaa tgtatgtaat tatttcctat attgttataa
    17221 aatatagtta taatttacag atttttataa aaatagataa aaggggaaca gttgctatga
    17281 aaaagatact cattaaaacc atgacagttt tagctttact cgtatttcta gtaggtggaa
    17341 tgacaacagg caaaacggat gcagcgagta acacggcgaa tcaagatctc atcattatta
    17401 acaagtatta taataaacta gcttattatc ataatggata ccttgaaatg gtggtgcccg
    17461 tagcaacagg gaagacgtgg gataaaacac cagttggatt tttcaaagtc gtcaataaaa
    17521 ttaaaaatcg accatattac acaggaaaga ttccaggtgg agatcctcgc aatccattag
    17581 gaaagcgttg gttagggata aatgccaatg gaacttatgg tgatacgtat ggaattcatg
    17641 gaaataacaa tgaaagcagc attggaaaat atgtcagctt aggttgcgtt cgaatgcata
    17701 atgc
//
