LOCUS       NZ_LWAI01000053        27201 bp    DNA     linear   CON 07-APR-2024
DEFINITION  Priestia endophytica strain 3618_1C 3618_1C_contig_57, whole genome
            shotgun sequence.
ACCESSION   NZ_LWAI01000053
VERSION     NZ_LWAI01000053.1
KEYWORDS    WGS; RefSeq.
SOURCE      Priestia endophytica
  ORGANISM  Priestia endophytica
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
REFERENCE   1  (bases 1 to 152600)
  AUTHORS   Lekota,K.E., Mafofo,J., Rees,J., Muchadeyi,F.C., Madoroba,E. and Van
            Heerden,H.
  TITLE     Comparison of Bacillus endophyticus and B. anthracis characteristics
            using whole genome sequence analysis and microbiological analysis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 152600)
  AUTHORS   Lekota,K.E., Mafofo,J., Rees,J., Muchadeyi,F.C., Madoroba,E. and Van
            Heerden,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2016) Biotechnology Platform, Agricultural
            Research Council, 100 Soutpan Road, Pretoria, Gauteng 0110, South
            Africa
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-MAY-2015
            Assembly Method                   :: CLC Genomics workbench v. 7.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 330.0x
            Sequencing Technology             :: Illumina HiScan SQ
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003269975.1-RS_2024_04_07
            Annotation Date                   :: 04/07/2024 05:04:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,413
            CDSs (total)                      :: 5,355
            Genes (coding)                    :: 5,223
            CDSs (with protein)               :: 5,223
            Genes (RNA)                       :: 58
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 44 of 132
            Pseudo Genes (incomplete)         :: 88 of 132
            Pseudo Genes (internal stop)      :: 43 of 132
            Pseudo Genes (multiple problems)  :: 35 of 132
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:25:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 27201
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LWAI01000053.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27201
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..27201
                     /SMILES="NC(C(O)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27201
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:7201](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..7201)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            complement(<1..2639)
                     /locus_tag="A4U60_RS20345"
                     /old_locus_tag="A4U60_20180"
     CDS             complement(<1..2639)
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (2-26). E-value: 2.3e-12.
                     Score: 38.0. Matches aSDomain:
                     nrpspksdomains_A4U60_RS20345_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (5-306). E-value:
                     3.4e-115. Score: 376.2. Matches aSDomain:
                     nrpspksdomains_A4U60_RS20345_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (466-870). E-value:
                     2.4e-123. Score: 403.7. Matches aSDomain:
                     nrpspksdomains_A4U60_RS20345_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503051.1"
                     /locus_tag="A4U60_RS20345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20180"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_142674277.1"
                     /sec_met_domain="Condensation (E-value: 2.4e-69, bitscore:
                     226.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8e-127, bitscore:
                     416.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDVTDIYGLSPLQKGILFHTLYDQDDDHSFSYIVQVGFLLGGRL
                     NVATFEKAWEYVIHRHEVLRSVFVWEEVEKPLQAVYQHIPFTIHQEDWSALSIEGREKK
                     LHQFLTTDRRKGFLLDEAPLMRVTAIKEAEEETRIIWTHHHILLDGWSVSLIFSEVMEV
                     YLKMIKGELFNLPKSLPYKKYVQWINKQDQSQADKFWTEELKGFHAPTPLAMERKDQGQ
                     EKGYGECVYQVSEELTENLQEWVRNSRLTLNTLVQGAWAYLMSRYSGENDVVFGVTSSG
                     RPTELIGAESMVGLFINTLPTRIRVTNETAVVDWLRKIQMKEMERRQYEYNSLVDIQGW
                     SEVPRNSSLFHTLYVFENYPIQGDRNVDLRLLEVQSAEQTNYPLTLIVMPGKEITLKLM
                     YDRNYFNEETINRIQGHLSQTLIQMTKSLDSKLSEITHLTMEEQTQLLEEWNNTQVKYS
                     SESMIQTAFEKQVKKTPEAIAVIYENEQMTYKELDERANQLAHYLQKRGVGPDSLVGVY
                     MERSTQMMVALLGILKSGGAYVPLDPTYPESRLRYILEDASIEVLVTQEKLKNLGISQR
                     IETICMNQDGTAIEKEESTVCTSSVTGRNLAYVMYTSGSTGNPKGVMIEHHSVINYLEW
                     MQHQYPLSEKDVILQKTPFSFDVSVWELFWGLSVGACVSILPPGGEKDPSIIAEVIEKH
                     QVTIVQFVPSMLSVFLEHFNHIELKLKCSSVRHVFSGGEELSSGLVRRFQQQWNQSGQV
                     KLTNFYGPTEATIYVNAFDIQPNQEFVSIGQPIQNTQLYVLDQNQRLQSVGVEGELYIG
                     GAGLARGYLNRPKLTAERFVPHPFQLGERLYQTGDLVRYLTDGNLEFIGRMDHQVKMRG
                     FRIELGEI"
     CDS_motif       complement(3..65)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20345_0011"
                     /evalue="2.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="879"
                     /protein_start="858"
                     /score="35.6"
                     /tool="antismash"
                     /translation="FIGRMDHQVKMRGFRIELGEI"
     aSDomain        complement(30..1241)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS20345_AMP-binding.1"
                     /evalue="2.40E-123"
                     /label="A4U60_RS20345_AMP-binding.1"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="870"
                     /protein_start="466"
                     /score="403.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEKQVKKTPEAIAVIYENEQMTYKELDERANQLAHYLQKRGVGPD
                     SLVGVYMERSTQMMVALLGILKSGGAYVPLDPTYPESRLRYILEDASIEVLVTQEKLKN
                     LGISQRIETICMNQDGTAIEKEESTVCTSSVTGRNLAYVMYTSGSTGNPKGVMIEHHSV
                     INYLEWMQHQYPLSEKDVILQKTPFSFDVSVWELFWGLSVGACVSILPPGGEKDPSIIA
                     EVIEKHQVTIVQFVPSMLSVFLEHFNHIELKLKCSSVRHVFSGGEELSSGLVRRFQQQW
                     NQSGQVKLTNFYGPTEATIYVNAFDIQPNQEFVSIGQPIQNTQLYVLDQNQRLQSVGVE
                     GELYIGGAGLARGYLNRPKLTAERFVPHPFQLGERLYQTGDLVRYLTDGNLEFIGRMDH
                     QVKMR"
     aSModule        complement(30..2624)
                     /domains="nrpspksdomains_A4U60_RS20345_Condensation_DCL.1"
                     /domains="nrpspksdomains_A4U60_RS20345_AMP-binding.1"
                     /incomplete
                     /locus_tags="A4U60_RS20345"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(147..233)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20345_0010"
                     /evalue="3.90E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="831"
                     /protein_start="802"
                     /score="57.5"
                     /tool="antismash"
                     /translation="VGVEGELYIGGAGLARGYLNRPKLTAERF"
     CDS_motif       complement(723..749)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20345_0009"
                     /evalue="5.40E+00"
                     /label="C4_DCL_171-183"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="639"
                     /protein_start="630"
                     /score="1.3"
                     /tool="antismash"
                     /translation="NYLEWMQHQ"
     CDS_motif       complement(762..821)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20345_0008"
                     /evalue="3.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="626"
                     /protein_start="606"
                     /score="35.0"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGNPKGVMIEH"
     CDS_motif       complement(1014..1055)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20345_0007"
                     /evalue="9.10E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="542"
                     /protein_start="528"
                     /score="18.7"
                     /tool="antismash"
                     /translation="LGILKSGGAYVPLD"
     CDS_motif       complement(1560..1682)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20345_0006"
                     /evalue="1.00E-19"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="360"
                     /protein_start="319"
                     /score="63.0"
                     /tool="antismash"
                     /translation="QMKEMERRQYEYNSLVDIQGWSEVPRNSSLFHTLYVFENYP"
     aSDomain        complement(1722..2624)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS20345_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="3.40E-115"
                     /label="A4U60_RS20345_Condensation_DCL.1"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="306"
                     /protein_start="5"
                     /score="376.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILLDG"
                     /tool="antismash"
                     /translation="DIYGLSPLQKGILFHTLYDQDDDHSFSYIVQVGFLLGGRLNVATF
                     EKAWEYVIHRHEVLRSVFVWEEVEKPLQAVYQHIPFTIHQEDWSALSIEGREKKLHQFL
                     TTDRRKGFLLDEAPLMRVTAIKEAEEETRIIWTHHHILLDGWSVSLIFSEVMEVYLKMI
                     KGELFNLPKSLPYKKYVQWINKQDQSQADKFWTEELKGFHAPTPLAMERKDQGQEKGYG
                     ECVYQVSEELTENLQEWVRNSRLTLNTLVQGAWAYLMSRYSGENDVVFGVTSSGRPTEL
                     IGAESMVGLFINTLPTRIRV"
     CDS_motif       complement(1731..1826)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20345_0005"
                     /evalue="3.40E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="303"
                     /protein_start="271"
                     /score="61.2"
                     /tool="antismash"
                     /translation="DVVFGVTSSGRPTELIGAESMVGLFINTLPTR"
     CDS_motif       complement(2064..2102)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20345_0004"
                     /evalue="5.40E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="192"
                     /protein_start="179"
                     /score="9.6"
                     /tool="antismash"
                     /translation="PYKKYVQWINKQD"
     CDS_motif       complement(2148..2213)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20345_0003"
                     /evalue="3.40E-10"
                     /label="C3_DCL_135-156"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="164"
                     /protein_start="142"
                     /score="32.4"
                     /tool="antismash"
                     /translation="HHHILLDGWSVSLIFSEVMEVY"
     CDS_motif       complement(2430..2546)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20345_0002"
                     /evalue="6.50E-16"
                     /label="C2_DCL_024-062"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="70"
                     /protein_start="31"
                     /score="50.6"
                     /tool="antismash"
                     /translation="SYIVQVGFLLGGRLNVATFEKAWEYVIHRHEVLRSVFVW"
     aSDomain        complement(2562..2633)
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS20345_NRPS-COM_Nterm.1"
                     /evalue="2.30E-12"
                     /label="A4U60_RS20345_NRPS-COM_Nterm.1"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="26"
                     /protein_start="2"
                     /score="38.0"
                     /tool="antismash"
                     /translation="DVTDIYGLSPLQKGILFHTLYDQD"
     CDS_motif       complement(2580..2618)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20345_0001"
                     /evalue="4.20E-04"
                     /label="C1_dual_004-017"
                     /locus_tag="A4U60_RS20345"
                     /protein_end="20"
                     /protein_start="7"
                     /score="13.2"
                     /tool="antismash"
                     /translation="YGLSPLQKGILFH"
     gene            complement(2642..7201)
                     /locus_tag="A4U60_RS20350"
                     /old_locus_tag="A4U60_20185"
     CDS             complement(2642..7201)
                     /NRPS_PKS="Domain: Condensation_Starter (5-299). E-value:
                     7.7e-69. Score: 224.2. Matches aSDomain:
                     nrpspksdomains_A4U60_RS20350_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (457-866). E-value:
                     3.2e-121. Score: 396.7. Matches aSDomain:
                     nrpspksdomains_A4U60_RS20350_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (970-1038). E-value: 5.8e-27. Score:
                     85.7. Matches aSDomain: nrpspksdomains_A4U60_RS20350_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1048-1352). E-value:
                     8.2e-146. Score: 478.7. Matches aSDomain:
                     nrpspksdomains_A4U60_RS20350_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1362-1509). E-value: 1.5e-33.
                     Score: 107.7. Matches aSDomain:
                     nrpspksdomains_A4U60_RS20350_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016098520.1"
                     /locus_tag="A4U60_RS20350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20185"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_113754099.1"
                     /sec_met_domain="AMP-binding (E-value: 2e-130, bitscore:
                     428.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.9e-14, bitscore:
                     47.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 9.5e-66, bitscore:
                     215.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANEKCYPLSHPQRRIWYTEVIHSGRGICNLRFLFKLHQKMNYSI
                     LNRVVNRVISENDGLCIRLKENGHQEPEQYFVKHEEQKFEFFDFSSVKDSDFLEKWIEQ
                     KTQEIFTLFDSNLYYFALIKLNDNECAVFGNVHHIIMDGLSIQIFTSQIAKYYYELYGE
                     TDASILRNSYVQFLVNEQTYLNSSRFQKDQKFWLEEFKTLPSVTGLKSYNAYQVSTRAS
                     RETFTLSEHLKRKIEKFSEEYKFSIYTLFVAAFSLSMYRWTSSLDIALGMAYGNRMTKM
                     ERELIGMMVSTVPLRMDIKPEEEVLSFIGRVSRKQSKSLRHQKYPFDLLLKQINKENNR
                     NVRLFGTTIDYRDRDESGDSLWIPNCEEVQDFAVHIENLIDIDSLQVHIDYREELFSKE
                     EINRFFKIMLAILENAIKNPKQKVAEIEIISKEDKRKSLVEFNDPKLDFPSQATIHALF
                     EQQAMIYPNAIAVMYEKERVTYRELNERANQLAHYLQKKGVGPDSLVGLCVERSLEMIV
                     SILGILKAGGAYVPLDPTYPEQRLRYILEDASIQLVVAQESLKGLKWLPEDIKSIYLDR
                     DRDEIEQENRTLPISDVSPQHLAYVIYTSGSTGNPKGVMVEHHNVIRLFKSTECWYQFN
                     EKDTWTLFHSYAFDFSVWEIWGALLYGGKLVVVPYWISRSPKDFYRLLVEEEVTVLNQT
                     PSAFRQLIQVCEQEDKNKNLYLRYVIFGGEALDPISLLPWFQRYGEKDPQLINMYGITE
                     TTVHVTYSPITQDEVRHSSRSNIGKRIQDLEMYVLDACQQPVPIGVDGELYIGGAGLAR
                     GYLNRPELTAERFIPHPFSSEPKARLYRTGDLARYLPDGNLDYRGRIDHQVKIRGFRIE
                     IGEIESILNAHASIKEAVVIVREDPPGDKRLVAYVVGDGNVGAWREYLKAKLPSYMVPS
                     GFVMMESIPLTANGKVDREALPIPEEKKIKSTCVAPQNSNEEKLATIWKQVLGIKKVGI
                     HDNFFEIGGDSILSIQIISQASQLGLKLTPKQMFERPTIAELAQVVTENQGVQAEQGVV
                     TGDVPLTSIQYWFFEQEHPRPQYWNQSMLLRVRESVDMKLLEGAILNLLKHHDALRFRY
                     EQLPNGTWRQRNEGIDEQSVLRVVKRNNANEQVWNQVIQEEMNITQASFNLVTGPLMRV
                     VYFEDMLNGNDRLFWAIHHLVVDGVSWRILLEDLQAVYNQMKQGQRVHLPAKSTSFKEW
                     SERLQTYSDSGISKEVQDYWNEQAEKEVMKIPMDYPIQETTEESIDQVTRTLGVEETHT
                     LLQEVPVIHKTRINEVLLTALGQAIVDRTNQHKVSIHLEGHGREEMIEGVDLSRTVGWF
                     TSIYPVHLNFQGTTTPIEGLKAVKDQLRRIPNRGVDYGILRYLNKELLPFYQQQKPSIS
                     FNYLGQFDQVFSKESLFMQETGFTFLDHAPDSKPSHLIDVIGMVKDEKLHFVWMYSREQ
                     FSRLTIQAIADGMLKHLRLLINKPTTESAFTVSDFADAEDLTEESLSKVLLKLTKKRV"
     aSDomain        complement(2675..3115)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS20350_TIGR01720.1"
                     /evalue="1.50E-33"
                     /label="A4U60_RS20350_TIGR01720.1"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="1509"
                     /protein_start="1362"
                     /score="107.7"
                     /tool="antismash"
                     /translation="LKAVKDQLRRIPNRGVDYGILRYLNKELLPFYQQQKPSISFNYLG
                     QFDQVFSKESLFMQETGFTFLDHAPDSKPSHLIDVIGMVKDEKLHFVWMYSREQFSRLT
                     IQAIADGMLKHLRLLINKPTTESAFTVSDFADAEDLTEESLSK"
     aSModule        complement(2675..7186)
                     /complete
                     /domains="nrpspksdomains_A4U60_RS20350_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_A4U60_RS20350_AMP-binding.1"
                     /domains="nrpspksdomains_A4U60_RS20350_PCP.1"
                     /domains="nrpspksdomains_A4U60_RS20350_Epimerization.1"
                     /domains="nrpspksdomains_A4U60_RS20350_TIGR01720.1"
                     /locus_tags="A4U60_RS20350"
                     /monomer_pairings="Thr -> D-Thr"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(3044..3106)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20350_0012"
                     /evalue="1.30E-11"
                     /label="NRPS-E6"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="1386"
                     /protein_start="1365"
                     /score="36.5"
                     /tool="antismash"
                     /translation="VKDQLRRIPNRGVDYGILRYL"
     aSDomain        complement(3146..4057)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS20350_Epimerization.1"
                     /evalue="8.20E-146"
                     /label="A4U60_RS20350_Epimerization.1"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="1352"
                     /protein_start="1048"
                     /score="478.7"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="TGDVPLTSIQYWFFEQEHPRPQYWNQSMLLRVRESVDMKLLEGAI
                     LNLLKHHDALRFRYEQLPNGTWRQRNEGIDEQSVLRVVKRNNANEQVWNQVIQEEMNIT
                     QASFNLVTGPLMRVVYFEDMLNGNDRLFWAIHHLVVDGVSWRILLEDLQAVYNQMKQGQ
                     RVHLPAKSTSFKEWSERLQTYSDSGISKEVQDYWNEQAEKEVMKIPMDYPIQETTEESI
                     DQVTRTLGVEETHTLLQEVPVIHKTRINEVLLTALGQAIVDRTNQHKVSIHLEGHGREE
                     MIEGVDLSRTVGWFTSIYPVHLN"
     CDS_motif       complement(3149..3199)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20350_0011"
                     /evalue="1.30E-09"
                     /label="NRPS-E5"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="1351"
                     /protein_start="1334"
                     /score="29.9"
                     /tool="antismash"
                     /translation="DLSRTVGWFTSIYPVHL"
     CDS_motif       complement(3602..3667)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20350_0010"
                     /evalue="1.40E-11"
                     /label="NRPS-E2"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="1200"
                     /protein_start="1178"
                     /score="36.5"
                     /tool="antismash"
                     /translation="LFWAIHHLVVDGVSWRILLEDL"
     CDS_motif       complement(3881..3985)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20350_0009"
                     /evalue="1.20E-03"
                     /label="C2_LCL_024-062"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="1107"
                     /protein_start="1072"
                     /score="11.3"
                     /tool="antismash"
                     /translation="NQSMLLRVRESVDMKLLEGAILNLLKHHDALRFRY"
     aSDomain        complement(4088..4291)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS20350_PCP.1"
                     /evalue="5.80E-27"
                     /label="A4U60_RS20350_PCP.1"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="1038"
                     /protein_start="970"
                     /score="85.7"
                     /tool="antismash"
                     /translation="EEKLATIWKQVLGIKKVGIHDNFFEIGGDSILSIQIISQASQLGL
                     KLTPKQMFERPTIAELAQVVTEN"
     CDS_motif       complement(4574..4639)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20350_0008"
                     /evalue="1.40E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="876"
                     /protein_start="854"
                     /score="33.2"
                     /tool="antismash"
                     /translation="YRGRIDHQVKIRGFRIEIGEIE"
     aSDomain        complement(4604..5830)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS20350_AMP-binding.1"
                     /evalue="3.20E-121"
                     /label="A4U60_RS20350_AMP-binding.1"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="866"
                     /protein_start="457"
                     /score="396.7"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEQQAMIYPNAIAVMYEKERVTYRELNERANQLAHYLQKKGVGPD
                     SLVGLCVERSLEMIVSILGILKAGGAYVPLDPTYPEQRLRYILEDASIQLVVAQESLKG
                     LKWLPEDIKSIYLDRDRDEIEQENRTLPISDVSPQHLAYVIYTSGSTGNPKGVMVEHHN
                     VIRLFKSTECWYQFNEKDTWTLFHSYAFDFSVWEIWGALLYGGKLVVVPYWISRSPKDF
                     YRLLVEEEVTVLNQTPSAFRQLIQVCEQEDKNKNLYLRYVIFGGEALDPISLLPWFQRY
                     GEKDPQLINMYGITETTVHVTYSPITQDEVRHSSRSNIGKRIQDLEMYVLDACQQPVPI
                     GVDGELYIGGAGLARGYLNRPELTAERFIPHPFSSEPKARLYRTGDLARYLPDGNLDYR
                     GRIDHQVKIR"
     CDS_motif       complement(4727..4816)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20350_0007"
                     /evalue="6.70E-19"
                     /label="NRPS-A_a6"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="825"
                     /protein_start="795"
                     /score="59.9"
                     /tool="antismash"
                     /translation="PIGVDGELYIGGAGLARGYLNRPELTAERF"
     CDS_motif       complement(5348..5407)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20350_0006"
                     /evalue="2.50E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="618"
                     /protein_start="598"
                     /score="35.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGNPKGVMVEH"
     CDS_motif       complement(5603..5644)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20350_0005"
                     /evalue="4.60E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="533"
                     /protein_start="519"
                     /score="19.6"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       complement(6149..6265)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20350_0004"
                     /evalue="1.50E-08"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="351"
                     /protein_start="312"
                     /score="27.2"
                     /tool="antismash"
                     /translation="SRKQSKSLRHQKYPFDLLLKQINKENNRNVRLFGTTIDY"
     aSDomain        complement(6305..7186)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS20350_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="7.70E-69"
                     /label="A4U60_RS20350_Condensation_Starter.1"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="299"
                     /protein_start="5"
                     /score="224.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="CYPLSHPQRRIWYTEVIHSGRGICNLRFLFKLHQKMNYSILNRVV
                     NRVISENDGLCIRLKENGHQEPEQYFVKHEEQKFEFFDFSSVKDSDFLEKWIEQKTQEI
                     FTLFDSNLYYFALIKLNDNECAVFGNVHHIIMDGLSIQIFTSQIAKYYYELYGETDASI
                     LRNSYVQFLVNEQTYLNSSRFQKDQKFWLEEFKTLPSVTGLKSYNAYQVSTRASRETFT
                     LSEHLKRKIEKFSEEYKFSIYTLFVAAFSLSMYRWTSSLDIALGMAYGNRMTKMERELI
                     GMMVSTVPLRMDI"
     CDS_motif       complement(6314..6403)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20350_0003"
                     /evalue="2.00E-09"
                     /label="C5_starter_265-294"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="296"
                     /protein_start="266"
                     /score="29.8"
                     /tool="antismash"
                     /translation="DIALGMAYGNRMTKMERELIGMMVSTVPLR"
     CDS_motif       complement(6731..6796)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20350_0002"
                     /evalue="1.40E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="157"
                     /protein_start="135"
                     /score="24.4"
                     /tool="antismash"
                     /translation="VHHIIMDGLSIQIFTSQIAKYY"
     CDS_motif       complement(7010..7081)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20350_0001"
                     /evalue="1.00E-01"
                     /label="C2_starter_024-063"
                     /locus_tag="A4U60_RS20350"
                     /protein_end="64"
                     /protein_start="40"
                     /score="5.4"
                     /tool="antismash"
                     /translation="MNYSILNRVVNRVISENDGLCIRL"
     gene            complement(7216..8463)
                     /locus_tag="A4U60_RS20355"
                     /old_locus_tag="A4U60_20190"
     CDS             complement(7216..8463)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016108414.1"
                     /locus_tag="A4U60_RS20355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20190"
                     /product="MFS transporter"
                     /protein_id="WP_113754100.1"
                     /transl_table=11
                     /translation="MKTTDSKSLWKNRIYLQVFSAYSLLMLGVFIDMLAIMTIVGFEWE
                     VDPTMIGLIPVAYALPGILFSSWAGVIADRFRKIPIMMFCNLMVGLLTIALLFVQSIYW
                     LLLALMIRSIFIVFYYPAQQTLTRQIVSPDLLTKAVSINGIVEQGTKIVGPLIGGMLLS
                     WFQPEFCLIIRAISCLLATLVLLPTIKFKESLSREHIEKQQQSTWTAWLQGWGYVLSNR
                     IILSTMIFVTIAMAVLQLVDSQFPTLFKSLFPNDKSKMGYIISIIGLGGILGALLTQKL
                     KHFQYGWVVCGGMALMGIGFGGIGLITPDTVFILAYLISFIAGIGSGLMLVSNQVILQI
                     ESHQDQVGRVFGIQSSLTNAVLIISPAMSGPLVHLFGVTQLYVYGGIGLIIIGVIGVSL
                     QKYLWVKHEPIRVNNF"
     gene            complement(8556..>8705)
                     /locus_tag="A4U60_RS20360"
                     /old_locus_tag="A4U60_20195"
                     /pseudo=""
     CDS             complement(8556..>8705)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016123096.1"
                     /locus_tag="A4U60_RS20360"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20195"
                     /product="SDR family oxidoreductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="KSHLVDLRPLGRLGTPEEVAKTVLFLASEDASFVTGASLLIEDGG
                     YTAQ"
     gene            8837..9154
                     /locus_tag="A4U60_RS20365"
                     /old_locus_tag="A4U60_20200"
     CDS             8837..9154
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019393515.1"
                     /locus_tag="A4U60_RS20365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20200"
                     /product="hypothetical protein"
                     /protein_id="WP_113754101.1"
                     /transl_table=11
                     /translation="MKYHEYRNGHLIQTNKKFSALTKKQKEHIGRDLRERYIKMMKYPG
                     VKLPPKKREQILDEVYEIIEKKGIWIPFGEVKKYYYSRISSFIRSHQKQPQNHNQDKCA
                     F"
     gene            complement(9186..9362)
                     /locus_tag="A4U60_RS27255"
     CDS             complement(9186..9362)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4U60_RS27255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_172463524.1"
                     /transl_table=11
                     /translation="MSEDKKGSTNDLALWLGIGLFFGSLYGSLFHNIGLGIGMGLCFGV
                     AIGLSLEKKNKQK"
     gene            complement(9532..9849)
                     /locus_tag="A4U60_RS20370"
                     /old_locus_tag="A4U60_20205"
     CDS             complement(9532..9849)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019391030.1"
                     /locus_tag="A4U60_RS20370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20205"
                     /product="YfzA family protein"
                     /protein_id="WP_061805659.1"
                     /transl_table=11
                     /translation="MKNKPKKGRSILKREWVRPLIALLVLQLIFFVCDKNGWSMNFRDD
                     EGTVLDRFSKAKFFTEQFIPYENPTFNLFTAVFLVTLLPAAIIGAMKDLFSRKQTNHHA
                     G"
     misc_feature    9932..9945
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.36"
                     /tool="antismash"
     misc_feature    9934..9947
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.06"
                     /tool="antismash"
     gene            complement(10674..10931)
                     /locus_tag="A4U60_RS20375"
                     /old_locus_tag="A4U60_20210"
     CDS             complement(10674..10931)
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019391020.1"
                     /locus_tag="A4U60_RS20375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20210"
                     /product="ferredoxin"
                     /protein_id="WP_113715082.1"
                     /transl_table=11
                     /translation="MKMCKKYTIIDRETCIGCGACGAAAPDIYDYDEEGIASVRLDNNE
                     GTAIIPDELVDDMMDALEGCPTGSIKVAEKTFNCNPHEFE"
     misc_feature    10904..10922
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 26.15"
                     /tool="antismash"
     gene            complement(11022..11816)
                     /locus_tag="A4U60_RS20380"
                     /old_locus_tag="A4U60_20215"
     CDS             complement(11022..11816)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-248). E-value:
                     2.6e-31. Score: 101.1. Matches aSDomain:
                     nrpspksdomains_A4U60_RS20380_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019391019.1"
                     /locus_tag="A4U60_RS20380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20215"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_113754102.1"
                     /sec_met_domain="PF00561 (E-value: 9.1e-25, bitscore: 80.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 4.4e-10, bitscore:
                     33.4, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2e-21, bitscore:
                     70.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPYVQVKDLSIYYEIEGNGEPLVLLHGMSNNSKSWKEQIRELKND
                     YTVIAWDAPGYGRSSNPAEELRYFEEFAHILKTMIDELKLEKIYLLGHSMGAAIAIEFC
                     NFYSDRIKKLIIADPTRGAAALNEEENKRKLENRLFSIENLSPEEIADKRIKALLSPYA
                     SKEVYKRVKEIMSQVRPAGYRSVAYSLYHLNQMSLLSHITVPVLVVCGELDTVTPVNES
                     KAIHKELINSKFVIIPKGGHLCYQEEPRVFNSRIIEFLNENR"
     aSDomain        complement(11073..11756)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS20380_Abhydrolase_1.1"
                     /evalue="2.60E-31"
                     /label="A4U60_RS20380_Abhydrolase_1.1"
                     /locus_tag="A4U60_RS20380"
                     /protein_end="248"
                     /protein_start="20"
                     /score="101.1"
                     /tool="antismash"
                     /translation="PLVLLHGMSNNSKSWKEQIRELKNDYTVIAWDAPGYGRSSNPAEE
                     LRYFEEFAHILKTMIDELKLEKIYLLGHSMGAAIAIEFCNFYSDRIKKLIIADPTRGAA
                     ALNEEENKRKLENRLFSIENLSPEEIADKRIKALLSPYASKEVYKRVKEIMSQVRPAGY
                     RSVAYSLYHLNQMSLLSHITVPVLVVCGELDTVTPVNESKAIHKELINSKFVIIPKGGH
                     LCYQEE"
     CDS_motif       complement(11508..11552)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS20380_0001"
                     /evalue="7.00E-05"
                     /label="NRPS-te1"
                     /locus_tag="A4U60_RS20380"
                     /protein_end="103"
                     /protein_start="88"
                     /score="15.4"
                     /tool="antismash"
                     /translation="YLLGHSMGAAIAIEF"
     gene            complement(11935..12117)
                     /locus_tag="A4U60_RS20385"
                     /old_locus_tag="A4U60_20220"
     CDS             complement(11935..12117)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="A4U60_RS20385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20220"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_242447736.1"
                     /transl_table=11
                     /translation="MKIVDNDTKASNIKKRNPLQLAQLPEDHVAAYVLLASDESRAITG
                     EVISSDGGLSVRGLG"
     gene            12120..12989
                     /locus_tag="A4U60_RS20390"
                     /old_locus_tag="A4U60_20225"
     CDS             12120..12989
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="A4U60_RS20390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20225"
                     /product="MFS transporter"
                     /protein_id="WP_242447737.1"
                     /transl_table=11
                     /translation="MDLADLGPAIGSVVLVLVISSFHWQAAFFMLAAFNLFINIPMFIF
                     LTRNTPEEHPGVSKDELAFIRHSDYEKEEKITGNKNFAQDYRFWLVWLGMLVNSFLFFG
                     ISIWLPTYLIEAKGFEQEGMSSITSLSWLFALGFVLACGFLADKTNRLSLMATILFSMT
                     ALFLTLAVFIPNPILAGVCMGLAMGCQGGVFHLSNMLIVKYSTPKTAGRAAGLLGFANI
                     MGGFSSYIMGWLRDLSDGDFSTSIAMLIFASLLGVSAYVFTIKKESTELHENYLPIQKT
                     KGPDSKTL"
     gene            13418..13597
                     /locus_tag="A4U60_RS20395"
                     /old_locus_tag="A4U60_20230"
     CDS             13418..13597
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013084255.1"
                     /locus_tag="A4U60_RS20395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20230"
                     /product="small acid-soluble spore protein H"
                     /protein_id="WP_019391006.1"
                     /transl_table=11
                     /translation="MDAQRAQEISNSTNMANIMYNGKNVYIEHVDQENGTATIHNIDEP
                     NNKQSVSISDLTEQ"
     gene            complement(13721..15208)
                     /gene="zwf"
                     /locus_tag="A4U60_RS20400"
                     /old_locus_tag="A4U60_20235"
     CDS             complement(13721..15208)
                     /EC_number="1.1.1.49"
                     /GO_function="GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="zwf"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019391002.1"
                     /locus_tag="A4U60_RS20400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20235"
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="WP_113754103.1"
                     /transl_table=11
                     /translation="MDSMTFVLFGATGDLAKRKIFPALYNLFLDEKIPGSISIIGSGIE
                     EISDIDFQNQVRQSVETFSRRLINNHSKIEDFISSFCYKSLDATNKEDYKDLLELVQRR
                     EEELRIPENRMFYLSVAPDFFDLIALNIKESGLGSTKGWKRLIIEKPFGHDLTSAQDLN
                     EKLSQAFKEDEIYRIDHYLGKSMVQNLEALEFANPILQSLWNNQHIANVQITASETVGV
                     EKRADYYDRAGAIRDMVQNHMLQLVMMTAMHLPKKLSSHEIRDEKRKVMESLRSIKKED
                     VGLHIIRGQYDAGEIHGQPVVKYTDEPKIDSSSQNDTFVAARLWIDNSFWNGVPFYIRT
                     GKRMKDKSTRIVIEFKNYLKDLYKNQDETVEPNLLIIEINPHENVALQLNSKNSLKNGK
                     IEPVRVEFAADQKGAPEAYERLIFDALTDDSTFFAHWKEVELAWGWIQPILEAFEENLL
                     PLYSYSSGSHGPDEANRLLEENGFKWWFDEEYSERKN"
     misc_feature    15380..15394
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.42"
                     /tool="antismash"
     gene            complement(15688..16716)
                     /locus_tag="A4U60_RS20405"
                     /old_locus_tag="A4U60_20240"
     CDS             complement(15688..16716)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016766187.1"
                     /locus_tag="A4U60_RS20405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20240"
                     /product="NADH:flavin oxidoreductase/NADH oxidase"
                     /protein_id="WP_113754104.1"
                     /transl_table=11
                     /translation="MNDLFTPYKLKGLEMKNRIVMPPMCQYSVNAKDGIATDFHYIHYV
                     SRAIGGAGFIMIEMTDVEPDGRISDYDLGLWSDDQIPALKRIVDACHQYGAKVGIQIAH
                     AGRKAEDAEVPVAPSAIAFDENYKQPRELSSEEVKEMVEKFRKAVQRAVKAGVDAIEIH
                     GAHGYLIHQFHSPLTNKRDDEYGQDLTKFGCEVLRAAKKEMPEDMPLMMRISAKEYVED
                     GYDIEESIEFAKKYQEEGVDIFDISSGGEGPIGAGGRPGTHAGYQVPLAREIKKALNVP
                     VIAVGRLDEPTLANAVIGNEEADLIAVGRGMLRNPYWALEASKKLNKETEIPKQYVDGF
                     RR"
     misc_feature    complement(16846..16859)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.44"
                     /tool="antismash"
     misc_feature    16971..16984
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.49"
                     /tool="antismash"
     misc_feature    17089..17103
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.86"
                     /tool="antismash"
     gene            complement(17182..17613)
                     /locus_tag="A4U60_RS20410"
                     /old_locus_tag="A4U60_20245"
     CDS             complement(17182..17613)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016766186.1"
                     /locus_tag="A4U60_RS20410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20245"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_019391000.1"
                     /transl_table=11
                     /translation="MEGNQRHNLLDNWLSIINVQTNIANTLERALEEQYSLSLKEFYVL
                     YFLSQTDDKQLRLQQLQEMVGLSQSAISRLVGRMEAKSCGALERHLCEDDRRGIYTRLT
                     PLGEEKLNKALATFEEILQSILAEGKMQSEWQSFLNKFQ"
     gene            complement(17943..19037)
                     /locus_tag="A4U60_RS20415"
                     /old_locus_tag="A4U60_20250"
     CDS             complement(17943..19037)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010530548.1"
                     /locus_tag="A4U60_RS20415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20250"
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="WP_113754105.1"
                     /transl_table=11
                     /translation="MKNIKKLFEGVTLGNTLLDNRVGVAPMTRTSATAKGLVTDEIISY
                     YTSFAKGGFGLIITEGTYTDHQYSQCYFYQPGMIDEEQAKTWKQLVDSVHEAGAKIFMQ
                     LEHTGPLSQGNRFVGGTIAPSSVQPKGEQLEFYGGKGPFPLPKEATKEEIKEVINGFVH
                     SAKRAQSVGFDGIEIHGANGYLLDAFLTDYTNHRKDEYGGSTENRVRLLVEIAKAVREE
                     VGPNFTVGIRISQSKVNDYEHKWVGKEKDAKIIFSQLGQSGLDYIHVTEHHAQQPAFNT
                     SDLSLAALAKKYGGIPVIANGHLEDPLAASEMIERGEADVITLGKGALANHDWVQKVKN
                     DEQLREFNQEEILRPNAKIKEFEI"
     gene            19202..20065
                     /locus_tag="A4U60_RS20420"
                     /old_locus_tag="A4U60_20255"
     CDS             19202..20065
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019392725.1"
                     /locus_tag="A4U60_RS20420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20255"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_113754106.1"
                     /transl_table=11
                     /translation="MELRQLVTFKTIVEKEGFKKAADELGYAQSSVTNHIKELEAELNQ
                     PLFDRLGKRIVLTAFGKQFFPYAIKIINLYTEIKERAHQNHEPIGDLTIGATEAITTCR
                     LPQILLQYSKKYPKVNLSIKSVDHRNITSELQQGNIDIALVLEKDDWTAKDLYFEKIKG
                     EPMMLLTPLKNKGNRKTVLYTERTCAYKRIFDDYIEDHHIEVDNSVDFASVETIKQCVI
                     SGLGASLLPYFTVKKELQDGLLNGKIIQGEQYGVSTFIAYHKDKWVSPAMESIISLIHD
                     YAKSWD"
     gene            complement(20314..21411)
                     /locus_tag="A4U60_RS20425"
                     /old_locus_tag="A4U60_20260"
     CDS             complement(20314..21411)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019390999.1"
                     /locus_tag="A4U60_RS20425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20260"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_113754107.1"
                     /transl_table=11
                     /translation="MIYLIAVLLVLCLAIVSFINFHPVFGGSVKKEQKENYSSLNNYKN
                     GRFVNLVPTNENMGVADMFSMLKDSFRNRGERKPNQNLPILEIDWDKVNSEKDSLTWFG
                     HSAFLLSIDGKKMLVDPMLGFVASPVSFVGSKRYSQDTLILIDRLPRIDAVLLTHDHYD
                     HLDYPSIRKLKNKVEHFFVPLGVSPHLLRWGIAKEKITELNWWEEREFHGLTVALTPSK
                     HFSGRGVFNRNTTLWGGWVVLGQKTRFYTSGDGGYDEHFKEIGKKYGPFDMTLMEGGQY
                     DRRWSDIHMKPEESVQANIDVGGKRMMLIHWGAFTLAFHPWTEPVERALMEAQKADVNM
                     VVPKIGETVELTGEISHSSSVWWRM"
     gene            21833..22252
                     /locus_tag="A4U60_RS20430"
                     /old_locus_tag="A4U60_20265"
     CDS             21833..22252
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /locus_tag="A4U60_RS20430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20265"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_225985299.1"
                     /transl_table=11
                     /translation="MAEKANINEHLISMNIHKIMYELNEVTHETTDIQERVIKHAISYI
                     ENHFTKEINLKELAQYVHLTPFHFSRVFKKYTGFSPYEYIINFRINYAKKLLQNTNTSI
                     KEISIESGFNSDTHFMTTFKKHTNLTPKQFREIQF"
     gene            complement(22348..22878)
                     /locus_tag="A4U60_RS20435"
                     /old_locus_tag="A4U60_20270"
     CDS             complement(22348..22878)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013055250.1"
                     /locus_tag="A4U60_RS20435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20270"
                     /product="IseA DL-endopeptidase inhibitor family protein"
                     /protein_id="WP_113754108.1"
                     /transl_table=11
                     /translation="MKKIGLVLSSIAIFFALSTGATAQTNSQTLTNANAIKIAASASDH
                     FWNALHGYKKTPCTQGTFNYKGTPYTYLCPEFDTKTELTNYLSETFTNNAVEKGLTKYS
                     YITYNGKLAHPVGDGFSMLEWTKAKAKLVYQTSTVRSYEFTVPTVDGATVKRTVTFYKA
                     GTQWKVNKFDAVQ"
     misc_feature    23174..23187
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.19"
                     /tool="antismash"
     gene            complement(23620..24939)
                     /locus_tag="A4U60_RS20440"
                     /old_locus_tag="A4U60_20280"
     CDS             complement(23620..24939)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015137 - citrate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015746 - citrate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003236221.1"
                     /locus_tag="A4U60_RS20440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20280"
                     /product="citrate:proton symporter"
                     /protein_id="WP_113754109.1"
                     /transl_table=11
                     /translation="MQRGIWVVLSILGFCMIATFLFLVIFKRLSVIVAFVFVSVAFALI
                     GGFGENMGEMMMDGIITVAPTAVMIVFAILYFGLMIDVGLFDPMVSRILTFVKGDPLKV
                     VMATAIITIIVGLDGDGSSTFMITISAMLPLYKRLGMNRLVLACVVALAAGVMNIIPWG
                     GPLVRASASLGVEVSDLFIPLIPVMISGLLWTLFSSYILGKKERDRLGVINLEATQTKG
                     LAEQSVAAEKGGTHLFWFNLLLTLTLMVLLVMEVLPIQILFAIAFTMALFVNFPNPKEQ
                     QERILSHAHSFVTISTLVFAAGIFIGVFSGTKMMDAMANSIVSIVPDWLGPHLALVVAL
                     TSLPLNFIFSPDAYYFGILPILSETAANFGVNPAEVGRAALLGHSTVGFPLSPLVPATF
                     ILIGLVGVDFGEHQKFLLKWAIGTTVVMTIIAVLTGAIPF"
     misc_feature    24979..24993
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.0"
                     /tool="antismash"
     gene            25181..25489
                     /locus_tag="A4U60_RS20445"
                     /old_locus_tag="A4U60_20285"
     CDS             25181..25489
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4U60_RS20445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4U60_20285"
                     /product="inner-membrane translocator"
                     /protein_id="WP_113754110.1"
                     /transl_table=11
                     /translation="MENFILAVFICIIFLLNICSFIFLKRSQWRFVLWGLSIMLLSPII
                     GFLSGSLLFHFQHLEQGETGEGAAYGGAILGLFTCANGFLILLGSFIYVLVLKLRAR"
     misc_feature    25733..25747
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.92"
                     /tool="antismash"
     gene            26066..26491
                     /locus_tag="A4U60_RS20450"
                     /old_locus_tag="A4U60_20290"
     CDS             26066..26491
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014462104.1"
                     /locus_tag="A4U60_RS20450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20290"
                     /product="DUF4183 domain-containing protein"
                     /protein_id="WP_113754111.1"
                     /transl_table=11
                     /translation="MEKTKEGRVLTKERIIVVLVLVVILALIPDLLVARYWGRKVYQGP
                     QGPPGPPISGPIQTTSLLYFTFSDGQNLVYTNSDGFGEYGITEILSPNEVSYINLFING
                     ILQPQSNYQVENGKLTLLVDEAPSEGVPITLQFIIIN"
     gene            complement(26675..26959)
                     /locus_tag="A4U60_RS20455"
                     /old_locus_tag="A4U60_20295"
     CDS             complement(26675..26959)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018883638.1"
                     /locus_tag="A4U60_RS20455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_20295"
                     /product="DUF4183 domain-containing protein"
                     /protein_id="WP_113754112.1"
                     /transl_table=11
                     /translation="MPIIKPFMASRKFSATIGDGTGTGATFAIAATTFIDDTGATATAF
                     PASFAYYVLYINAQPQTADTSTLTTTTITIPGGDVLDDATPILVEIVVN"
ORIGIN
        1 tcaatttctc caagttcaat ccgaaaacca cgcattttca cttgatggtc cattctccct
       61 ataaattcta aattcccatc agttagatat cttactaaat ctcctgtttg atatagtcgt
      121 tctcccaatt gaaatggatg cggaacgaat ctttcagcag tgagcttcgg acgatttaag
      181 tatccgcgtg ctaaacctgc accaccaata tataattcgc cctctactcc taccgattgc
      241 aggcgttgat tttggtctaa tacatacaat tgcgtattct gtatcggctg gccaatagaa
      301 acaaattctt gattaggttg aatgtcaaat gcatttacgt aaatagttgc ttctgttggt
      361 ccataaaagt tggttagttt tacttgtccg ctctgattcc attgctgttg aaatcgtcta
      421 accaaccctg aacttagctc ttccccacca gaaaatacat gacgcacgga agaacatttc
      481 aatttcaatt caatatgatt gaaatgttct aagaaaacag ataacatcga aggaacaaat
      541 tgaacaatag taacctgatg tttttcaatc acttcagcta taatagaagg atctttctct
      601 ccacctggag gtaagataga tacacacgca cctacgctaa gaccccaaaa taactcccaa
      661 acagatacat caaatgagaa tggggttttc tgcaaaatca catccttttc agaaagtgga
      721 tattggtgtt gcatccattc gagataatta atcactgaat gatgctcaat catcactccc
      781 tttggattcc ctgtagatcc tgaagtatac ataacatatg ctaaatttct tcctgttaca
      841 ctacttgtac atacggttga ttcttctttt tcaattgcag taccatcttg attcatacaa
      901 attgtttcga tgcgttggga tatacctaga tttttcaact tttcttgcgt tactagtact
      961 tcgatgctag catcttctaa tatatagcgt aaccgactct ctggataagt aggatcaagt
     1021 ggaacataag ctcctcctga ttttagaatc cctagtaacg ctaccatcat ttgtgtcgaa
     1081 cgttccatat acactccaac tagagaatct ggacctacac cacgtttttg taaataatga
     1141 gctaactgat tagcgcgctc atccaactct ttataggtca tttgttcatt ttcataaata
     1201 accgcgattg cttctggcgt tttcttaact tgtttctcaa atgccgtttg aatcatactt
     1261 tcagatgaat attttacttg agtattattc cattcctcta gcaactgtgt ctgttcttcc
     1321 attgttaaat gagtaatttc agagagtttt gaatctaggc ttttcgtcat ctgaattaag
     1381 gtttgcgata agtgaccctg aatccgattt attgtttctt cattaaaata gttgcggtca
     1441 tacatcaact ttaacgtaat ttccttacca ggcattacaa tgagtgttaa aggatagttt
     1501 gtttgctccg cgctttggac ctctagtaat cttaaatcaa cattacggtc accttgaatg
     1561 gggtaatttt caaacacata caaggtatga aataaggaac tattccgcgg aacctcactc
     1621 cacccttgaa tatcaaccaa cgaattatac tcatattgtc ttcgttccat ttctttcatc
     1681 tgtatcttac gaagccagtc tactactgct gtctcatttg ttactcgaat tcgggtaggt
     1741 aatgtattaa tgaataggcc aaccatactc tctgcgccta tcaattcagt aggacgacca
     1801 gagctagtta cgccgaatac aacgtcattt tcaccgctat acctactcat caagtaggcc
     1861 caagcgccct gtactaacgt attcaatgtt aaccgactat ttcgtaccca ctcttgtaaa
     1921 ttctcagtaa gttcctcaga tacctgataa acacactctc catacccctt ctcctgtcct
     1981 tgatcctttc tttccatcgc taatggcgta ggtgcatgaa atccttttaa ttcttccgtc
     2041 caaaatttat ctgcttgact ttgatcttgt ttatttatcc actggacata ttttttataa
     2101 ggaagagact taggaagatt aaacaattct ccctttatca tcttgagata aacttccatc
     2161 acttcactaa agattagaga cacactccat ccatccaaca aaatatgatg atgtgtccaa
     2221 atgattctcg tttcttcttc tgcctcttta atcgcagtga ctctcatcaa cggtgcttcg
     2281 tctaataaaa atcctttcct acgatctgta gtcaaaaact ggtgtaattt cttctccctc
     2341 ccctcaattg acagagcgct ccaatcttct tgatgaatag taaaaggaat atgttggtaa
     2401 acagcttgca gaggcttttc tacttcctcc cacacaaata ctgaacgtag aacttcatgt
     2461 cgatgaatga cgtattccca agccttttcg aaagtagcaa cattcaatcg gccaccgagc
     2521 aagaagccta cttgtacaat gtaggaaaaa gaatgatcat catcttgatc gtataaagta
     2581 tgaaacagta ttcctttttg caaaggtgat aatccatata tatcagtaac atctcccatc
     2641 gttacaccct cttctttgtt aatttaagta agactttact caagctttct tccgtaaggt
     2701 cctctgcatc agcaaagtca gataccgtaa aagcagactc tgttgttggt ttatttataa
     2761 gtagacgaag atgcttcaac ataccatctg ctatcgcttg aattgttaat ctagaaaact
     2821 gttctctact atacatccaa acaaaatgta acttctcatc ttttaccata ccgataacat
     2881 caattagatg agatggtttg gaatctggag catgatctaa aaatgtaaac cctgtctctt
     2941 gcataaacaa agattctttg gaaaacactt gatcaaattg gcccaaatag ttaaagctta
     3001 ttgacggttt ttgctgctga tagaacggaa gtaattcttt attcaagtag cgtaaaatac
     3061 cataatcaac gccacgattc ggaattcgac gcaattgatc ctttacagcc tttaatcctt
     3121 caataggtgt tgttgttcct tgaaaattaa ggtgaacagg ataaatactc gtgaaccacc
     3181 ccactgtccg tgatagatca acaccttcaa tcatctcttc tctcccgtgc ccttctagat
     3241 gaatagaaac cttatgctga tttgtacgat cgactatagc ttgtcctaat gccgtcaata
     3301 gtacctcgtt aatccttgtc ttatgaatca ctggaacttc ttgtaacaac gtatgggttt
     3361 cttctactcc taaagtcctt gtcacctgat caatcgattc ttctgttgtt tcttgtattg
     3421 ggtagtccat cggaatcttc atcacttctt tttctgcctg ttcattccaa taatcttgta
     3481 cttcttttga aataccagaa tcactgtatg tctgcaatcg ttccgaccac tctttaaaag
     3541 atgtactttt cgcaggtaaa tgaaccctct gaccttgttt catctggttg tatacagcct
     3601 gtaaatcttc caatagaatc ctccatgata ctccatctac tactaaatga tggatcgccc
     3661 agaataatcg atcgttccca ttcaacatat cctcgaaata aactactctc attaacggac
     3721 ctgtaactaa attgaaacta gcttgagtga tattcatctc ttcttgtatc acttgattcc
     3781 acacttgttc attagcattg ttccgtttta ccacacgaag tacagactgc tcatcaattc
     3841 cctcatttct ctgcctccat gttccatttg gtaactgttc gtatcggaaa cgtaaagcat
     3901 catgatgttt aagtaagttt aatatagctc cctctagtaa cttcatgtcc acactctctc
     3961 ttactcttaa aagcatcgat tgattccaat actgtggacg tggatgttct tgctcgaaga
     4021 accagtactg aattgaagta agtggtacat cgcctgtcac cactccctgc tccgcttgta
     4081 ctccctgatt ttctgtgact acttgtgcca actcggcaat agttgggcgt tcaaacattt
     4141 gctttggagt aagttttaat cccaattgac tcgcttgtga tatgatctga atgctgagaa
     4201 tcgagtcccc accaatttca aagaagttat catgaattcc caccttttta atccctaata
     4261 cttgcttcca aatagtagcc agtttttctt cgttactatt ctgaggggca acacatgtac
     4321 ttttaatctt cttttcctct ggtataggta aggcctcacg atcaactttc ccgttagcag
     4381 ttagtggaat agattccatc attacaaatc ctgaagggac catatagctc ggtagtttcg
     4441 ctttaagata ctctctccac gcacctacat tcccatcccc tacaacatat gccactaatc
     4501 gtttatcacc tggcggatct tctcgaacaa tcacaacagc ctcttttata gatgcatgtg
     4561 cgtttaaaat agattcaatt tccccaatct caattcggaa gccacggatt ttcacctggt
     4621 gatcaattcg tccacgataa tccagattcc catccggcaa gtatctcgct aagtctcctg
     4681 ttcgatataa tcttgctttc ggttcactac taaatggatg aggaatgaag cgttctgcag
     4741 ttaattcagg tctatttaaa tacccacgtg caagccctgc tccaccaata tatagttcac
     4801 catctacacc aataggcaca ggctgttgac aagcatctag cacatacatt tctaaatctt
     4861 gaatccgttt tccaatatta cttcgtgaag agtgccggac ctcatcttga gtaatcggag
     4921 aataagtaac atgaacggta gtttctgtaa ttccatacat attaattagc tgtgggtcct
     4981 tctctccata cctttgaaac cacggtagca agctaatagg gtctaacgct tccccaccaa
     5041 atatcacata gcgtagatac aagtttttat tcttgtcttc ttgttcacac acctgtatta
     5101 attgtcgaaa tgcggaaggt gtctgattta gaactgtgac ttcttcctct actaatagtc
     5161 gatagaaatc cttaggcgat cgactaatcc agtaaggaac aacaaccaat tttccaccat
     5221 acaataacgc tccccaaatt tcccatactg agaaatcaaa tgcataagaa tgaaaaagcg
     5281 tccaagtatc tttttcatta aactgatacc aacattccgt tgatttaaat aaacgaatta
     5341 cattgtgatg ctctaccata acgcccttcg gattccctgt cgatcccgaa gtatagatta
     5401 cgtaagctag gtgttgagga cttacatcag aaatcggtaa agtcctattt tcttgctcaa
     5461 tctcatctcg atcacgatcc aggtaaattg atttgatatc ttctggtaac catttcaatc
     5521 cttttaaact ttcttgcgct acaactaact gaatgctagc atcctctaaa atataccgga
     5581 gtcgctgctc tggatatgtt ggatcgagtg gaacataagc tccaccggcc ttcaaaattc
     5641 ccaaaatact tacaatcatt tcaagagaac gttcaacaca aagcccaacc aaagaatcgg
     5701 gtcctactcc ttttttctgt agataatgag ctaactgatt tgcacgttca tttaactccc
     5761 tataggtaac cctctccttt tcatacataa ctgcaatagc atttggataa atcattgctt
     5821 gctgttcgaa caatgcatgg atagttgctt gagatggaaa atcaagctta ggatcattga
     5881 actctactaa actttttctt ttatcttctt ttgaaatgat ttcgatttca gctaccttct
     5941 gctttgggtt tttaattgca ttttctaata ttgctaacat aattttaaaa aaacggttta
     6001 tctcttcttt agaaaatagc tcttcacgat aatcaatatg tacttgtaaa gagtctatat
     6061 caatcaaatt ttcaatatgt actgcaaaat cttgcacttc ttcacaattt ggaatccaaa
     6121 gtgagtcacc actttcatca cgatctctat aatcgatcgt agttccgaaa agcctaacat
     6181 ttctgttatt ctctttatta atctgcttta ataacaaatc aaatgggtat ttctgatgtc
     6241 gtaatgattt actttgtttt ctagataccc gaccaataaa tgaaagtact tcttcttcag
     6301 gtttgatatc cattcttaga ggtactgtac tcaccatcat tccaattaat tcccgctcca
     6361 ttttagtcat acgattgcca taagccattc ctaatgcaat atcaagcgat gaggtccacc
     6421 gatacatcga caacgaaaac gcagcaacaa aaagagtata tatactaaat ttatactctt
     6481 cagaaaattt ttctatcttt ctcttcaaat gctccgataa tgtaaacgtc tcacgtgatg
     6541 ctctggtact aacttgatac gcattatagg acttcaatcc cgtcacagat ggaagtgttt
     6601 tgaattcctc taaccagaat ttttgatctt tttgaaagcg actactattc aagtatgttt
     6661 gttcattgac cagaaactga acatatgaat ttctaagtat gctcgcatca gtctcaccat
     6721 aaagctcata ataatattta gcaatctgac tagtaaaaat ttggattgat aaaccatcca
     6781 taataatgtg atgaacattc ccaaagactg cacattcatt atcgtttaat tttattaaag
     6841 cgaaatagta taaattagag tcaaataatg taaatatttc ttgtgttttt tgctcaatcc
     6901 atttttccag aaaatctgaa tctttcacgg aactgaaatc gaaaaactca aatttttgtt
     6961 cttcatgttt aacaaaatat tgttcgggtt cctgatgccc attttctttc agtctgatgc
     7021 acagaccatc attttcactg ataacacgat tcacaactcg atttaatatt gaataattca
     7081 ttttttgatg aagtttgaac aaaaacctta aattacatat ccctctaccg gaatgaataa
     7141 cttctgtata ccatattctc ctctgtggat gacttaacgg ataacatttc tcattagcca
     7201 taaaaaatct tcccctcaaa aattatttac tcttataggt tcatgtttaa cccataaata
     7261 tttctgtaat gaaaccccaa ttactccaat gataataagc ccgatccctc cataaacata
     7321 gagttgagtt actccaaaca aatgaactag tgggccactc atagcaggag aaatgattaa
     7381 gactgcgttt gttaaactac tttgaattcc aaatactctt cctacttgat cttgatggga
     7441 ttctatttgt aaaatgactt gatttgatac aagcataagt ccacttccaa taccagcaat
     7501 aaaactaatc agataagcta aaatgaagac cgtatcggga gttatcagac caatccctcc
     7561 aaaaccaatt cccattaaag ccatgcctcc acatactacc caaccatatt gaaagtgttt
     7621 taatttctga gttaataatg cgccaagtat tccaccaaga ccaataatag aaatgatgta
     7681 tcccatttta cttttatcat ttggaaacaa gctcttaaat aaagtaggga actgtgagtc
     7741 tactaattgt aatactgcca tagctattgt aacgaaaatc atggttgata atattatccg
     7801 attagataac acataacccc aaccttgtaa ccaagcggtc caagtgcttt gctgttgctt
     7861 ttcaatatgt tctcttgaca gagattcctt aaattttatt gtaggcaaca gaaccaaagt
     7921 agctagtaaa caacttatcg cccttataat gaggcagaac tctggctgaa accagctcag
     7981 caacattcct cctataagtg gacctactat cttggttccc tgctcaacta taccgttgat
     8041 acttactgct ttagtaagca aatcaggaga aacaatctgt cttgttagtg tttgctgtgc
     8101 aggataatag aaaacgataa aaatagaacg aatcattaat gctaataaga gccaataaat
     8161 actctggaca aataaaagag caattgttaa tagaccaacc ataagattac aaaacatcat
     8221 aataggaatt tttctaaaac gatctgcaat cacacctgcc catgaactaa ataaaattcc
     8281 aggaagtgca tacgcaacag gaatcaatcc aatcatggtg gggtctactt cccattcaaa
     8341 accaacaata gtcataatgg ctaacatatc aataaatacc ccaagcataa gcagcgaata
     8401 cgcagagaaa acctgtaaat aaatcctatt tttccataga ctttttgagt cagtagtttt
     8461 cataagaacg ggctccttaa gttgattaaa ataaatgttc taattgcata gttccatctc
     8521 ccaattaatt gatttatccg gttaacatta agtagctatt gagctgtata gcctccatcc
     8581 tctattaata agcttgcacc ggtgacaaag gaagcatctt cactagctaa aaacagaaca
     8641 gttttagcaa cttcttctgg tgttccaagt ctacctagag gacgaaggtc gacaagatgt
     8701 gatttatatc ctcttttata tccattcttt tcattcttct aaaatcctcc aatatattac
     8761 aaatttttct tctgaatttc ttatcggcat cccctatccc ttttttgtta ttataggaat
     8821 aaaggaggca taaaagatga agtatcatga atatcgaaat ggtcatctca tccaaacaaa
     8881 taagaaattt tctgctttaa ctaagaagca aaaagagcac attgggcgag atttaagaga
     8941 gcgatatata aagatgatga aatatcctgg agtaaaactt cctccgaaaa aacgagagca
     9001 aatattagat gaagtatatg aaataattga gaaaaagggt atatggattc cttttggaga
     9061 ggtaaaaaaa tattattaca gcaggatctc ttcttttatt cgtagtcatc agaaacagcc
     9121 acagaaccac aatcaagata agtgcgcttt ctaatttacc tatcatttaa tgattaagac
     9181 acatactact tctgcttatt cttcttctca aggcttaagc caatcgctac tccgaagcaa
     9241 agacccattc caatacctaa accaatatta tgaaatagtg agccatataa agatccaaaa
     9301 aataaaccaa ttcctaacca tagtgctaaa tcatttgtac ttcccttttt gtcttcagac
     9361 aaaaaatcgc tcccctatat catcatttct tcttatagtt actaatacgg agcaaaacga
     9421 tatagatttc atagtttaaa atggatagca tggtttttaa gtcttcattt tgaatatagt
     9481 ccgtataagg agctagccaa ttcagtaatt gcgcttttaa agatacaact gttatcctgc
     9541 atgatgatta gtttgttttc tggaaaatag atctttcatc gcacctataa tggcagcggg
     9601 aagtaaagtg acaagaaaaa ctgctgtgaa taagttgaat gttggatttt catatggaat
     9661 gaattgttcg gtaaaaaatt tagctttaga gaatctatct aacactgttc cctcatcatc
     9721 tctgaagttc attgaccatc cattcttatc acagacaaaa aagattaatt gcaaaacgag
     9781 taatgctata agggggcgta cccattctcg ttttaaaata gaacgtcctt tttttggttt
     9841 atttttcatt caactagttc tccttttcat aatctaaaag gaactaaatt ctccttcttc
     9901 aatgcacctt acaaacacta taaattataa cattttttac aaaaaaagta atataaaatc
     9961 cagaataaaa cttatatatc tcacgcactt accttctttc cctgcaaatg tagcgataag
    10021 gagtcgctat tctgtctgaa ggaagtaaga ggaatatagt aaaaaagctt aagcatataa
    10081 aaaaccataa aagtaaaagt ctcctttact aaaacaagga atcatcttat tgttatattt
    10141 cttagttaac ttaaaaacct ttcctcttca gcgtcaacta tcacatgact gaagaggaaa
    10201 ggttccttca atgtttaatt ctgactctac aaattgacaa gcttggtaga aaattagact
    10261 ttttctattg tttcagtaag tctaacttgt tttttattta taaatgacga atgggatgca
    10321 tattatgcgt aaacaaatgt tcttatagta tagatagtta gaaaaaaggt ggctacatcg
    10381 tttctgctaa tctccaaatt gcaaactctt gatttttatg tttttcagca gtcgttaaat
    10441 ccccatttgc tgtatcaaga actcgccttt gaactccccc acttagcata gcttgaattt
    10501 aatttatgga acacaaccca ctctattaga aaaatctttc cgaatgcaaa ttcgttttac
    10561 tttttagggg tatttattat actgattaga ggctagctaa ataatgtttt aatttcaaca
    10621 aggcatatta atctaacatg ttttgcaaat accttctaaa atgtatggga ttttcattca
    10681 aattcatgag gattacaatt gaaagtcttt tcagctactt taatggatcc tgttgggcat
    10741 ccttctaaag catccatcat atcgtctacc aattcatcag ggataatagc tgttccttca
    10801 ttattatcta atctaacaga tgcaatacct tcttcgtcat aatcgtaaat gtcaggggca
    10861 gcagccccac atgctccgca accaatacaa gtttctctat ctataattgt atacttttta
    10921 cacatcttca ttttcctttc ccctctctca gcaccccagt ttattatgat gcttttctaa
    10981 ataagattta gaaatctaag gtaatgtcaa tagtttttca tttacctatt ttcattgaga
    11041 aattctataa ttcttgaatt gaatactcta ggttcttctt gataacacaa atgtccacct
    11101 tttggaataa ttacaaactt ggagtttatt aattccttat gaatggcctt tgattcgttt
    11161 acaggagtaa cggtatcaag ttcgccacaa acaacaagaa caggaactgt tatatgagat
    11221 aacaaactca tttgatttag atgatagagt gaatatgcta ctgaacgata tcctgctggt
    11281 cttacttgtg acataatctc ttttactctc ttatacactt cttttgaagc gtaaggagat
    11341 agcaatgctt ttattctctt gtctgctatc tcctctggag aaaggttttc aattgaaaat
    11401 aatcgatttt ctaacttcct cttgttctct tcttcattca aagcagcagc ccctctggtc
    11461 ggatccgcta tgataagttt tttaattcta tcagaataaa agttacaaaa ttctattgca
    11521 atggctgccc ccattgaatg accgagaaga tagatttttt ctagctttag ctcatctatc
    11581 atagttttca gaatatgggc aaactcttca aaatatctta attcttcagc gggattcgag
    11641 cttcttccat aacctggagc atcccaagca ataactgtat aatcgttctt taattcacgt
    11701 atttgttctt tccatgactt tgaattgttg ctcatcccat gcagcaatac taatggctct
    11761 ccattacctt ctatctcgta ataaatactt aagtctttta cttgtacata aggcataata
    11821 caagtctcct ctattcattc tagatatatc gtttttaaga agggtggtga attctcaatt
    11881 ttcagaatta aaactcttta cttttctata aaaaaggatt cattcctata atgtttaacc
    11941 aagaccccgt actgacaatc cgccgtcact agaaataact tcacctgtga ttgcacgtga
    12001 ctcatcagat gctaataata catatgctgc aacgtgatct tctggtagct gagcaagttg
    12061 aagagggttt cgttttttta tgttacttgc tttagtatca ttatctacaa ttttcacaaa
    12121 tggacttagc ggatttagga cctgctattg gatctgttgt actggtactc gttatttcct
    12181 catttcactg gcaggcagct ttctttatgt tagcagcctt taacttattt attaatatcc
    12241 ccatgtttat cttcctgaca agaaatacac cagaagaaca cccaggagtt agtaaagatg
    12301 aactagcttt tatccgtcat tcggattatg aaaaagaaga aaaaataaca gggaataaaa
    12361 attttgctca agattaccgt ttctggcttg tctggctcgg tatgctagta aattcttttc
    12421 tcttcttcgg gatcagtatt tggctcccta catatctcat agaagccaaa ggatttgaac
    12481 aagaaggcat gtcaagcatt acttcacttt cctggttatt tgcccttggg tttgttttag
    12541 catgcggttt tcttgccgat aaaacaaatc gtctaagttt aatggcaacc attttatttt
    12601 caatgacagc cctcttttta acactagctg tttttatccc taatccaatt ttagctggag
    12661 tttgtatggg tctggcaatg ggctgtcagg gaggagtttt ccatctaagt aatatgctaa
    12721 tagtaaaata ttcaacgcct aaaacagctg gacgggcagc tggtttgtta ggttttgcaa
    12781 atattatggg cggcttttca agctatatta tgggatggct tcgtgaccta tcagatgggg
    12841 acttcagtac atcaattgct atgctaattt ttgcatctct tctaggtgta agcgcttacg
    12901 tatttactat taagaaagaa tctactgagc ttcatgaaaa ttacttgcct atccaaaaaa
    12961 cgaagggtcc tgactctaaa actctttgat agcactacag aaacttcata gccttcacaa
    13021 tgacaaatcc atatccaaca taaaatgagc ctctttttta ataacacaat cattattata
    13081 ggtaccttat tcgtctaacc tttcatatct tttaaatttc atcttttcct tttttaactg
    13141 tttaatagtt aatcattaga ctcttattat gtctaataat aggtaagagg tagaatgacg
    13201 aacagccaag gctattttga aaaagcactt ggctgactag gtatcactag atttatctac
    13261 atgaaaggca acctccttta ttcctgaata aacgaactga tgtaaatata ttaggaggta
    13321 atcaacgatg atatctcgtt ttaccctctt tttatgtata taaagcagct aaacgtaaat
    13381 actgtaactg ttataaatga aaaaggaggc tgtcaacatg gatgcacaaa gagcacaaga
    13441 aatttctaat tcaacgaaca tggctaatat aatgtataat ggaaaaaatg tttatattga
    13501 acatgtagat caagaaaatg gaacagctac aattcataat attgatgaac caaataataa
    13561 acaaagtgtt tctatatcag atttaacaga acagtaattc aattaaaaaa gatatataag
    13621 acagtgtgtt tcttttaaaa gactccatgt taggagtctt ttttatattc gtattgatag
    13681 atgttatact ttcctaatgt tttgttttaa agtggccgaa ctaattttta cgttcagaat
    13741 attcttcatc aaaccaccat ttgaacccgt tctcttctag taaacgatta gcttcatctg
    13801 ggccatggga acctgatgag tatgaataaa gaggcaaaag attttcttca aaggcttcta
    13861 gtattggctg aatccatccc caagctaatt caacttcttt ccaatgagca aagaaggtgg
    13921 aatcatctgt taaagcatcg aagattagac gttcataagc ttcaggtgcc cctttttgat
    13981 ctgctgcaaa ctccactcta accggttcaa tttttccatt ttttaatgag tttttactat
    14041 tcaactgtaa ggctacattt tcatgtgggt taatttcaat aattaagaga tttggttcaa
    14101 ctgtctcatc ctgatttttg tatagatctt ttaagtagtt tttgaattca ataacaattc
    14161 gagttgactt atccttcatt ctttttccag tccgaatgta aaaagggact ccattccaaa
    14221 aggaattatc aatccataag cgtgcagcta caaatgtatc attttgagaa gaagaatcaa
    14281 ttttaggttc atcggtatat ttcacaactg gttgaccatg aatttcacct gcatcatatt
    14341 gaccacggat aatatgcaga cctacatctt ctttctttat cgaacgaagt gactccatca
    14401 ctttcctctt ttcatcacgg atttcgtgtg aactaagttt tttaggaaga tgcatagcag
    14461 tcatcattac aagttgtagc atgtgattct gaaccatatc ccgaattgcg cctgctcggt
    14521 cataataatc agctcttttt tctactccga ccgtctcact tgctgtaatc tgaacattag
    14581 caatatgttg gttgttccat aatgattgaa gaatagggtt ggcaaattct aaagcctcca
    14641 agttttgaac catagatttt ccaagataat gatcaattcg ataaatttca tcttctttga
    14701 atgcttgact taatttctca tttaagtctt gcgcagatgt taaatcatgc ccaaatggtt
    14761 tttcaataat aagacgcttc catccttttg tagaacctaa tccactttct ttgatgttta
    14821 atgcaatgag atcgaaaaaa tctggtgcta ccgataaata aaacatccgg ttttccggaa
    14881 tccttaactc ttcttcacgc cgttgaacaa gctctaataa atctttatag tcttccttat
    14941 ttgtcgcatc taaggatttg taacagaaag agcttataaa atcctctatt tttgaatgat
    15001 tatttatcaa tcgtcgggaa aaggtttcta ctgattgtct cacctgattt tgaaaatcta
    15061 tatcagatat ttcttctata cctgacccaa taatagaaat agacccaggt attttctcat
    15121 ctaaaaataa attatataga gcagggaaaa tttttctttt agccaaatct cctgtcgctc
    15181 caaataaaac aaaagtcatc gagtccattc cacaatcctc cttttgataa aattatttat
    15241 ttgatttttt acattaactg caaagaacta tatctaattt tgattccgtt taaatatttc
    15301 tttattggtt tcactagaaa ctatttcatg agaggatacc actaactgat aaacaaaatt
    15361 cccttgtttt taggaagttt tcccactttg aaaagtttgt ccttttgctt tatcaattat
    15421 gtacaggata gtaggatgga caaatgctat cagcagaata agagaatgct ttttatccct
    15481 tctaatccta taattaaaag attctataag aagcaggaga tttatttctt actgaactga
    15541 aggatattaa tttaaacaag tagcaaaaaa ggaccttcga ctgaagatcc tttttctccc
    15601 tactaaatat tttatgattt aattctgctt agttactatt tatcataatg gcaagcttat
    15661 cttaaataga tatatttgaa tgtaagctta acgtctaaaa ccatccacgt attgtttagg
    15721 aatttcagtt tctttgttta attttttcga tgcttctaat gcccagtaag gatttcttaa
    15781 catgcctcgg ccaacagcaa taaggtctgc ttcctcattt ccaatcactg cgttagcaag
    15841 ggttggttcg tctagtcttc ctacagcaat aacaggtaca ttaagtgctt ttttaatttc
    15901 tcttgcaaga ggcacttggt atcctgcgtg tgttccagga cgtccccctg ccccgattgg
    15961 accttctcca cctgaagaga tgtcaaagat atcaacgcct tcttcttgat attttttcgc
    16021 aaattcgatg ctttcttcga tatcataccc atcttctaca tattcttttg cagaaatacg
    16081 catcattaat ggcatatctt ctggcatttc ctttttagct gcgcgaagaa cttcacaacc
    16141 aaacttcgtt aaatcttgtc catactcatc gtcacgtttg tttgttaatg gagaatggaa
    16201 ttgatgaatt aagtagccat gagcaccatg aatttcaatt gcatcaacgc ctgcttttac
    16261 tgcacgttgt accgctttac ggaacttttc gaccatctct ttcacttctt cagatgaaag
    16321 ttcacgaggt tgcttataat tctcgtcaaa agcaatggca gatggtgcta caggaacttc
    16381 tgcatcttct gctttacgtc ctgcgtgggc aatttgaata cctacttttg ctccatattg
    16441 gtgacaagca tctacaatgc gtttgagtgc tgggatttga tcatcagacc ataaacctaa
    16501 gtcgtaatct gaaattcgtc cgtctggttc tacatctgtc atttcaatca taataaatcc
    16561 agctccacca attgcccgac ttacataatg tatataatgg aagtctgtcg caattccatc
    16621 tttcgcattt accgaatact ggcacattgg aggcataaca atacggtttt tcatctccag
    16681 cccttttagt ttataaggtg taaataaatc gttcattcta aaaactcctt tattattttt
    16741 tatactttaa tgaacaccca aaacaactgg aaggtgaaaa accttctcca cttctaacat
    16801 catcgatcat cttttgggct attcatcatt catacgtttt caatatgcat gcgcacacat
    16861 ttaaattact atccctatca tgtatctatc aaatgatatt tcatcattca ctgtagttca
    16921 aagaccagcc tatatgaata cctctaattt taaaagcgac aaacttaaca tgtatgcgca
    16981 cgcatataac ttaccatctt atttttcttc tgtcaaacgt taattttgca taaattttat
    17041 tagaaattca cgcatcatta taacgattga gttcatttaa aaacattaag aattttcgtt
    17101 caataaaaag taaaatgggt agtagataga atcaagaaca cccttatatc tatttctatc
    17161 ctcctacacc catatccttt attattgaaa tttgtttagg aacgattgcc actcactttg
    17221 catttttcct tctgctaaga ttgattgaag aatttcttca aaagtagcta aagctttgtt
    17281 taatttttct tcccctagcg gtgttaaccg agtgtaaata cctcgacggt catcttcaca
    17341 taggtgtctc tctaatgctc cacagctttt tgcttccatt cttccaacta accttgaaat
    17401 cgcactttga ctcaatccaa ccatctcttg caactgctga agtcttaatt gcttatcatc
    17461 tgtttgtgat aaaaaataaa gaacataaaa ctcttttaat gatagactgt attgttcctc
    17521 tagcgcacgt tctaatgtat ttgcaatgtt tgtttgtaca ttaatgatgg atagccaatt
    17581 atctagaaga ttatgtcttt gattgccttc catacaaacc cctcctattt tatctacatc
    17641 atttgttagc tcactgaact acataatagt tactataata gcatataaac tacattcatt
    17701 attaatattt tattttacta agtcaaattt atagaaataa tcgagagcta ttaatatgat
    17761 catgtttagc ttactaaaat atgctgtatt ccctaaatat acatttttgg acgacttttt
    17821 tctatcgtac ataaagtgaa gtaacatgtt caagatgggc gagaatgaga ttgattataa
    17881 tataaaagct gattcccctg ttaaggaatc agctttttaa gaaatgataa tttatagacg
    17941 acctatattt caaattcttt aatttttgca ttaggtctta aaatttcttc ttgattaaac
    18001 tctcttagtt gttcgtcatt ttttactttt tgaacccaat cgtggttagc aagcgctcct
    18061 tttcctaatg tgatgacatc cgcttctcct ctttctatca tttcactcgc tgctaaagga
    18121 tcttctagat gaccatttgc aatcactgga atgcctccat atttttttgc caaagcggca
    18181 agagataaat cgcttgtatt aaaagctggt tgttgggcat ggtgctctgt aacatggata
    18241 taatctaagc cagattgccc taattgacta aagatgattt tagcatcctt ctcttttccg
    18301 acccatttat gttcatagtc attgacttta ctttgtgaaa ttctaatgcc taccgtaaag
    18361 tttggtccta cctcttccct taccgctttt gctatttcca ctaacaatcg aactcgattt
    18421 tctgtagatc ctccatactc gtccttacga tgatttgtat aatcagttag aaaagcatct
    18481 aataaataac cattggctcc atgaatttct attccatcaa aaccaacaga ctgagcgcgt
    18541 ttggctgaat gaacaaatcc gtttattact tctttaatct cttcttttgt tgcttctttc
    18601 ggaagaggaa acggcccttt tcctccgtaa aattcaagct gttctccttt aggctggaca
    18661 gaggacggag caattgtccc tccaacaaaa cgatttcctt gtgaaagcgg tcctgtgtgt
    18721 tctaactgca tgaaaatttt tgctcctgct tcatgaacag agtcaacgag ttgtttccat
    18781 gtttttgctt gttcttcatc aatcatacca ggctgataaa aataacactg actgtattga
    18841 tgatcagtat acgttccttc cgtaataatg agaccaaatc ctccctttgc aaaagaagta
    18901 tagtaagaaa ttatttcatc tgttactagc ccttttgcag tagcgcttgt acgagtcatc
    18961 ggagctactc caacccgatt atctagcaga gtattcccta atgtaacacc ctcaaatagt
    19021 ttttttatat ttttcatagc taaaactccc tcttctcatt tatctatttc tttagattaa
    19081 aaacttcatc aactagtgaa gctaaataca attatattgt aatgaaccca atgaatttag
    19141 taaaatagat ataaatgaat aaaacgttca gtaaaactga acgaagaagg agttagaggc
    19201 tatggagctt cgacagcttg tcacatttaa aacaattgta gagaaagaag gattcaaaaa
    19261 agcagctgat gaacttgggt atgctcaatc atctgttaca aatcatatta aagagttaga
    19321 agctgagctt aaccaacctt tattcgatcg tttagggaaa cggatagttc ttactgcttt
    19381 cggtaaacag ttctttccct atgcaatcaa aattattaac ctttacacag aaatcaaaga
    19441 acgagcccat caaaatcatg aacctatagg agatttaaca attggagcaa cagaagctat
    19501 cacaacatgt cgcttaccac aaatattgct ccaatatagc aaaaaatatc ccaaggtgaa
    19561 tctgtccatc aagtctgttg atcatcgaaa tattacgtct gaacttcaac aagggaatat
    19621 tgatatagca ctagtattag aaaaagatga ttggactgca aaggatttat attttgaaaa
    19681 aattaagggg gaaccaatga tgttacttac tcctttaaaa aacaaaggaa acaggaaaac
    19741 cgttctatat acagagcgaa cgtgcgctta caaaagaatt tttgatgatt atatcgaaga
    19801 tcatcatatc gaagtggaca atagcgttga tttcgccagt gtagagacga ttaaacaatg
    19861 tgttattagt ggacttggtg cttcattatt accttatttc acagtcaaaa aagagcttca
    19921 agatggactg ttaaatggaa agataattca aggtgaacag tacggtgttt ctacatttat
    19981 tgcttatcat aaagataaat gggtgtctcc agcgatggaa agtatcattt ctttaattca
    20041 cgactatgct aaaagttggg attaggcgtg cagttatata tttcttcttg aaattaatga
    20101 ctgatgattt atgcaaaaac catcctcaga tggagtaaaa ttacgaggat ggtttttaag
    20161 tatttatatt ttttattctc taaaaacttt attctttttt aactttttta catcaactta
    20221 gttaacataa taattttata ataaacttat ctaccatgga ctttttatta ttcattagat
    20281 ccttatcctc attatttcca aaatctactt tacttacatt ctccaccaaa ctgaagatga
    20341 atgtgatatc tctcctgtta attcaacagt ttctccaatc ttaggaacta ccatattcac
    20401 atctgctttt tgtgcctcca ttaaggctct ttctacaggt tctgtccaag gatgaaaagc
    20461 aagcgtaaaa gctccccaat ggattaacat catccgcttt ccaccaacat cgatattagc
    20521 ttgcacagat tcttcaggct tcatatgaat gtcagaccag cgtcgatcat attggccacc
    20581 ttccattaag gtcatatcaa aaggtccata tttttttcct atttctttaa aatgttcatc
    20641 atatcccccg tctccgctcg tataaaaacg cgttttttgt ccaagaacga cccaccctcc
    20701 ccatagagtc gtatttcgat taaaaactcc tcttccagaa aagtgttttg atggtgttag
    20761 cgctactgtt aagccgtgaa actccctttc ctcccaccag ttcagttcag tgattttttc
    20821 tttggcaatc ccccatcgaa ggaggtgggg actaacaccg agaggaacaa agaaatgttc
    20881 cactttattc tttaactttc ggattgacgg ataatcaagg tggtcgtaat gatcatgagt
    20941 aagaaggaca gcatcaatac gaggtaatcg atcaataagt attaatgtat cttggctata
    21001 acgtttactt cctacaaacg aaactggtga agccacaaag cctagcatcg gatcaacgag
    21061 catcttcttc ccatcgatac taagtaaaaa ggcagagtga ccaaaccaag ttaaactatc
    21121 tttttcactg ttgactttat cccaatcaat ttcaagaata ggaaggtttt gatttggttt
    21181 gcgctctcct ctattcctaa aagaatcttt aagcatagag aacatatcag cgacacccat
    21241 attctcattc gttggtacta aattcacgaa tctcccattt ttataattat tgaggctact
    21301 ataattctcc ttttgttctt tctttacact tcctccaaat acaggatgaa agttgataaa
    21361 tgatacaatg gccagacata atacaagtaa aacagcgatt aaatatatca tcactagttc
    21421 cccattcctt tcaactttag ctatgtattt tttgaagatg tctcttgctt ctattagtat
    21481 actcttactc ttgtaaattc agaaaataaa aaagcctaac aaccatcata aagtggtgtt
    21541 agacttttta tttctatact ctccgtttag ttaaatgaaa tttctgattt ttaaacttat
    21601 taattctcat tttatttaaa gcgcttacga gtataactat taatttctga tgttcttaca
    21661 tactcttaaa attacgctca atctgttata atgataaccc tcttgttaat ggtttcattt
    21721 ctcaggtata tctagtgagc attattttaa tttactcttt gaaaaaagcg gctgtatttt
    21781 ttcagttaaa aacaattttg tgattccaga atgcataagt caaattgtcc gcatggcgga
    21841 aaaagccaat attaatgaac atttaatctc tatgaatatt cataaaatca tgtatgaatt
    21901 gaatgaagtc acacacgaaa caacggatat ccaagaaaga gtgattaaac atgctatttc
    21961 ctatatcgaa aatcatttta caaaagaaat taacttaaaa gagttagctc agtatgttca
    22021 tttaactcct ttccactttt cacgtgtatt taaaaagtac actggattct caccatatga
    22081 gtacattatc aacttccgaa tcaattatgc taaaaagtta cttcaaaaca caaacacatc
    22141 tattaaagaa atttcgattg aatccggatt taatagcgac actcacttta tgacaacatt
    22201 taaaaaacat acaaacttaa ctccaaaaca gtttagagaa attcaatttt agacactccg
    22261 tataaaaaca cactggataa agctcttatt tacatctcta taaagaaaaa agcaacttgc
    22321 ttctatagca agttgctttt ttttacttta ttgaactgca tcaaatttat ttactttcca
    22381 ttgtgttccc gctttgtaga atgttacagt acgttttaca gttgctccat caacagttgg
    22441 aactgtaaac tcataagaac gaactgttga tgtttgataa acaagttttg ctttcgcttt
    22501 tgtccactct agcatgctga atccgtcacc aactggatga gcaagtttgc cattgtatgt
    22561 gatgtagctg tattttgtta atcccttttc aactgcgtta tttgtaaatg tttcagataa
    22621 gtagtttgtt aattctgttt tagtatcaaa ttctgggcaa aggtatgtgt acggtgttcc
    22681 tttatagtta aatgtgcctt gtgtacatgg tgttttttta taaccgtgta gggcattcca
    22741 gaaatgatcg ctggcactag ctgcgatttt aatcgcattt gcatttgtta atgtttgaga
    22801 atttgtctgt gctgtagctc ctgtgcttag agcaaaaaat attgcgattg atgataatac
    22861 tagtccaatt ttcttcattt ctaaatcact cctcaatttt aaattcatat ctttatgtaa
    22921 cttaaatttg ttttgcatta cttttgttac atttatatta caacaaattt ttaaaaaaga
    22981 aaagtatttt ctctcttttt atgaaattta tttacttttt ctctattaat tccgtattaa
    23041 gagcgtgttt tttattaaaa ttaaaaatag agcggttttt atatgacaaa attgttacaa
    23101 taaagacatt ttacgactta ttttttattt acccttttct ttagaaaaaa actaataaaa
    23161 acgactctcg tttattttct aaaaaaagtt tagtaaaggt tcttagtcta ttcttactct
    23221 ggtgtcgtat tccttcttct ttcttttctt tatttaaaat tctggaacct tccttataaa
    23281 aagagagcta tattttttgg taacgcttac aaataccttt tccctccttt ttctatttca
    23341 aaccccccta gccttcatgt ttacaacata aaacgcattt ttgattcatt ttgaaaccca
    23401 aaatggaatg tactatataa tatcatcaaa cggttgggat atctctggaa ccgcctggat
    23461 taacatcact cgttctccaa ttgaagaagt ggatcagaaa ccacattata tttatcaaga
    23521 tttaaacgga atattagcgt tagtatgata tattgaaatg taaattcctt cgcaaacaaa
    23581 aagcgacgat gttaaaagtc atcgtcgctt tttgtttttt taaaatggaa tagctcctgt
    23641 taaaacagct attattgtca taactacagt tgttccgatc gcccatttta acaagaattt
    23701 ttgatgctct ccaaaatcca cccctacaag tccgattaaa ataaatgttg ctggaacaag
    23761 aggagataaa ggaaagccta cagttgaatg tcctaaaaga gcagctctcc ccacttctgc
    23821 tggattcacg ccaaaatttg ctgctgtttc acttaaaatc ggcaaaattc caaaatagta
    23881 cgcatcagga gaaaaaataa agttaagcgg aagacttgtt agagctacaa ctaatgccaa
    23941 gtgtggccct aaccaatctg gaacaattga aacaatagaa ttggccatag catccatcat
    24001 ttttgtacca ctgaaaacac cgataaaaat acctgccgca aacacaagag tactgatcgt
    24061 aacaaagcta tgagcgtgac tcaaaattct ttcttgctgt tcttttggat ttgggaaatt
    24121 gacaaataga gccatcgtaa aagcaatcgc aaataaaatt tggattggca atacttccat
    24181 aactaaaaga accataagcg ttaatgtaag cagtaaatta aaccaaaata agtgtgtccc
    24241 tcctttttca gctgctacag attgttctgc gagacctttt gtttgtgtgg cttctagatt
    24301 aataacacct aagcgatcac gttctttttt gccaagtata taagaggaaa agagcgtcca
    24361 taaaaggcct gaaatcataa caggaataag cgggataaat agatccgata cttcaacccc
    24421 aaggcttgca gaagctcgca ctaaaggccc tccccaagga ataatgttca taacgcccgc
    24481 tgctaatgca acaacacagg ctaagaccag tcgattcatt cctaaccgtt tataaagagg
    24541 gagcatggct gaaattgtaa tcataaaagt agacgaaccg tctccatcaa gcccaacaat
    24601 gattgtaata atagctgttg ccattacaac cttcagtgga tctcctttta caaacgtaag
    24661 aatacgagaa accattggat caaataaccc tacatcaatc attaatccaa agtataaaat
    24721 agcaaaaacg atcataaccg ctgttggggc gacagttata atcccgtcca tcatcatctc
    24781 gcccatattt tccccaaatc ccccaattag agcaaaagcg acagatacaa acacaaacgc
    24841 aacaatcact gagagccttt taaaaataac gagaaaaaga aaagtagcaa tcatacaaaa
    24901 acctaatatc gacaacacaa cccaaatccc cctttgcata taaaacagta cagttagaaa
    24961 ttcaccttaa aaagactaaa tattctaaaa attatatcta cacatgttct tcccctcact
    25021 ttcttcacaa cagtaaaact agtatgtaag ccttatcata gaagattaat gttcattata
    25081 gcatctctgt tgggcctttt tcgtagaaaa cataaatttt taaaactttt taggacgaac
    25141 ctcgtcaaaa attatacatc tacagataag gagagagaaa atggaaaatt ttattttggc
    25201 cgttttcatt tgtattatct ttctattaaa catttgctct tttatttttt taaaacgatc
    25261 acaatggcgg tttgttctat ggggactttc tataatgctc ttgtccccta tcattggatt
    25321 tttaagcggc agtttgctct ttcattttca acatcttgaa caaggtgaaa ccggagaagg
    25381 agctgcgtac ggaggcgcta ttttagggct ctttacatgt gcgaatggat ttctaattct
    25441 actaggtagt tttatatatg tactagtcct taaacttcga gctcgttaaa ttaaaaagac
    25501 aaacaaagag ggacaacaaa attcctcttt gtttgttttt ttctctattt aatgacgtgt
    25561 catgaaatac atatcataca ttgttttata ggcttctgta tttttctata aaatttctat
    25621 gaaaccttat tttaatagta aaaagagaga tttctatata aatttacttt tgtaagcatc
    25681 catagattta tataaaattt gtggtcgttt gcgtggtcat gaggtcggaa tgtggtcatc
    25741 atttttagta ttgagccaaa ctatgcagca tatcctttag taacacaagg aaaagtccag
    25801 attccctatc ataaaagggg tctggacttt ctaacttccc tgaaaatgta tcatgttaac
    25861 taaaaataaa tacactattc atattatacg aggttggata actagacact taacgcttaa
    25921 cccctaataa aatacatact ttgttgcttt caaaagagcg aggacaagca tccaaacaga
    25981 atctatgcat tttcatatat atatagtaag tctcaaataa aggaggctcc ttgtatgtgt
    26041 ttttattgta gaagagataa gtttcatgga aaagacaaag gaaggccgtg tactcacaaa
    26101 agagagaata attgttgtcc ttgttctcgt tgttattctt gctctaattc ccgacctcct
    26161 tgttgcccgg tattggggcc gcaaggttta ccagggccca caaggaccac caggtccgcc
    26221 aatttccgga ccaatacaaa caactagttt attatatttt actttttcag atggacagaa
    26281 ccttgtgtat acaaatagtg atggttttgg agaatatgga ataactgaga tactatcacc
    26341 aaatgaagtt tcctatatta atttgtttat caatgggatt ctccaacctc aaagtaatta
    26401 ccaagtagaa aatggaaaat taactttgtt ggtggatgaa gctccttcag aaggtgtacc
    26461 tattactctt cagtttataa ttattaatta atgaaatgat ttatatatat tatgatgcgt
    26521 tttacagctg aaaatggggt ggaatcgagg ttttaacaga gagaaacata gtctaagata
    26581 cattcttatc tcgattgaaa aaatgaatat aaccagaaag ggatcgatat tctccaagga
    26641 gaattgatcc ctttctggtt ataaaataat aggattagtt aactacaatt tcaacaagga
    26701 ttggtgttgc atcatcaagt acatcgccac ctggtatagt tatagtagta gtagtaaggg
    26761 tagaggtatc agctgtttga ggctgcgcat ttatatataa aacataataa gcaaatgatg
    26821 ctgggaatgc tgtagcggtt gcaccagtgt catctataaa agttgtcgct gcaattgcaa
    26881 acgttgcacc agtacctgta ccatctccta ttgtggcact aaattttctg gaagccatga
    26941 agggtttgat aataggcatt tatgttcact ccttcccaaa taaattaggg caaatttgtt
    27001 agcgaaaaaa cttgtccctt ttctagtcta ttattttatt tttttttggt aacggtaaat
    27061 gatttaatac ataagcacat ttttgtggaa ttttgatatg tttaaattgc tttttaatat
    27121 ttatttttag tttgtgtatg ttactggtca tttcatgcaa tggtttttat acattatttt
    27181 gagctcttaa tagctgtact a
//
