LOCUS       NZ_LWAI01000046        60324 bp    DNA     linear   CON 07-APR-2024
DEFINITION  Priestia endophytica strain 3618_1C 3618_1C_contig_5, whole genome
            shotgun sequence.
ACCESSION   NZ_LWAI01000046
VERSION     NZ_LWAI01000046.1
KEYWORDS    WGS; RefSeq.
SOURCE      Priestia endophytica
  ORGANISM  Priestia endophytica
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
REFERENCE   1  (bases 1 to 206893)
  AUTHORS   Lekota,K.E., Mafofo,J., Rees,J., Muchadeyi,F.C., Madoroba,E. and Van
            Heerden,H.
  TITLE     Comparison of Bacillus endophyticus and B. anthracis characteristics
            using whole genome sequence analysis and microbiological analysis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 206893)
  AUTHORS   Lekota,K.E., Mafofo,J., Rees,J., Muchadeyi,F.C., Madoroba,E. and Van
            Heerden,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2016) Biotechnology Platform, Agricultural
            Research Council, 100 Soutpan Road, Pretoria, Gauteng 0110, South
            Africa
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-MAY-2015
            Assembly Method                   :: CLC Genomics workbench v. 7.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 330.0x
            Sequencing Technology             :: Illumina HiScan SQ
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003269975.1-RS_2024_04_07
            Annotation Date                   :: 04/07/2024 05:04:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,413
            CDSs (total)                      :: 5,355
            Genes (coding)                    :: 5,223
            CDSs (with protein)               :: 5,223
            Genes (RNA)                       :: 58
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 44 of 132
            Pseudo Genes (incomplete)         :: 88 of 132
            Pseudo Genes (internal stop)      :: 43 of 132
            Pseudo Genes (multiple problems)  :: 35 of 132
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:25:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 43496
            Orig. end                         :: 103820
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LWAI01000046.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..60324
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="NRPS"
                     /product="betalactone"
                     /region_number="2"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..60324
                     /SMILES="NC([*])C(=O)NC(CS)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="betalactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..47011
                     /SMILES="NC([*])C(=O)NC(CS)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..47011
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:27011](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..27011
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            554..712
                     /locus_tag="A4U60_RS27205"
     CDS             554..712
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394109.1"
                     /locus_tag="A4U60_RS27205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_172460146.1"
                     /transl_table=11
                     /translation="MWVITVHSRKNTKMFEFNTEKEAREAFKDIEGSKILTEVIYFNSP
                     YLASSTV"
     gene            1226..1564
                     /locus_tag="A4U60_RS18330"
                     /old_locus_tag="A4U60_18170"
     CDS             1226..1564
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394110.1"
                     /locus_tag="A4U60_RS18330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18170"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_113753812.1"
                     /transl_table=11
                     /translation="MPKIEENQLFTVIIEWEVNPKYQQDLINGLTNQIETYFKNYDGFI
                     SSSFHASEDGKRVINYAQWISEEAWSNSFQASGRDEVQTTNDEIISRCEAKTLKLNKYR
                     VARVIENI"
     gene            complement(1837..2316)
                     /locus_tag="A4U60_RS18335"
                     /old_locus_tag="A4U60_18175"
     CDS             complement(1837..2316)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394111.1"
                     /locus_tag="A4U60_RS18335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18175"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_113753813.1"
                     /transl_table=11
                     /translation="MQIREMKEKDNQRMEQIIKHSLESFELNIPGTAYFDPQLSSLSQY
                     YQQQQNAKYWVAVNAQDEVIGGVGIAPFGQKKEVCELQKLYISPEAQGKGLSKELMKVA
                     LDFAKEHYTCCYLETFKELQAANFLYVKFDFRQLETPLDETEHNACDAWYIKELS"
     gene            complement(2948..3595)
                     /locus_tag="A4U60_RS18340"
                     /old_locus_tag="A4U60_18180"
     CDS             complement(2948..3595)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394112.1"
                     /locus_tag="A4U60_RS18340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18180"
                     /product="hypothetical protein"
                     /protein_id="WP_113753814.1"
                     /transl_table=11
                     /translation="MKNIPVNLLWFVCSIMLNALGNSFMIISNLGSSPWAAAGQNLAFI
                     LPLSTGACIIILNFFSFILSYLIKTKFTLAMIIKSMALTFVFGMFIDLFVHLHHIMYVP
                     ENLWIRCLYSLIGLNLMAVAVCIYFQSGSIYLPSDYLLKAFGKRMNNYTVGTMICTSIP
                     LSISILIILFQHHITGLGISTFLFMFGIGFLIDLYNRWIVIDKIPQQNMYSA"
     misc_feature    3857..3872
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
     gene            3945..4139
                     /locus_tag="A4U60_RS18345"
                     /old_locus_tag="A4U60_18185"
     CDS             3945..4139
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394113.1"
                     /locus_tag="A4U60_RS18345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18185"
                     /product="hypothetical protein"
                     /protein_id="WP_113753815.1"
                     /transl_table=11
                     /translation="MQKQQSITILLLMLGLASISLGMALKNVFEYSPIFGWFLGTFIFI
                     VNSFYTGKNLRNKDATNLK"
     gene            4701..5258
                     /locus_tag="A4U60_RS18350"
                     /old_locus_tag="A4U60_18190"
     CDS             4701..5258
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394114.1"
                     /locus_tag="A4U60_RS18350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18190"
                     /product="HPP family protein"
                     /protein_id="WP_242447719.1"
                     /transl_table=11
                     /translation="MIEKKLEKNVSNQVSIGVNIYLRKMKGEGRGKSKINYRDSIVSAT
                     GVLIAIIIISFMTLHLGYPMAIAPLGASCILIFEAHKGAWSQPRNVIGGHLLSTTSALI
                     IWSLLGKSLFSIGIVLAIVLILMALTNTLHPPAAASALVVVNSQTGWGFLVPISLGVLL
                     LIFISILYNNLFSKRQYPQHWL"
     gene            complement(6242..6577)
                     /locus_tag="A4U60_RS18355"
                     /old_locus_tag="A4U60_18195"
     CDS             complement(6242..6577)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003183745.1"
                     /locus_tag="A4U60_RS18355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18195"
                     /product="thioredoxin family protein"
                     /protein_id="WP_113753816.1"
                     /transl_table=11
                     /translation="MKEVTELISLDSIENFINNHKLSFLYISKPECVVCHAVLPQLRVL
                     LEQFPSIKLAHINANNVEEVAGRFSVFTVLVLLLFIEGTEFVREARFVHFEQLEQKLKR
                     IYQLYKD"
     gene            6964..7656
                     /locus_tag="A4U60_RS18360"
                     /old_locus_tag="A4U60_18200"
     CDS             6964..7656
                     /EC_number="5.1.1.-"
                     /GO_function="GO:0047689 - aspartate racemase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394116.1"
                     /locus_tag="A4U60_RS18360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18200"
                     /product="amino acid racemase"
                     /protein_id="WP_113753817.1"
                     /transl_table=11
                     /translation="MKKVVGIMGGMGPLATVDLMQKIISFTPAEKDQDHLHLITDNFPQ
                     IPDRTTAILGKGTDPTPFMIESAHRLESAGADFLVVACNTAHFFVKSVENAVSIPILHM
                     PLETAKFLKKHHFKKVGLLATDGTINTKLYQHSCHHYKIEVIEPNIQMQKEVMKGIYAI
                     KGGKLEQGSSYLSKIARSLIEEGAEAIIAGCTEIPLVLKSSSFSAIIDPTEILARAVIK
                     NANDLIKC"
     gene            7736..8605
                     /locus_tag="A4U60_RS18365"
                     /old_locus_tag="A4U60_18205"
     CDS             7736..8605
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002201263.1"
                     /locus_tag="A4U60_RS18365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18205"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_061804134.1"
                     /transl_table=11
                     /translation="MNIENIEAFLYVCQLGSFNKAAEALYLTQPSVTARIQSLEREMNI
                     KLFNRAGNKTSLTEKGEYFLPHAQKILQSYQEATYGLQQVFIPYELVIGSALSISNNVL
                     PNILPAFKSEFKDVRIKILTGHSKDILRKVINKEVDFGIIRTEAHSQIESIRLYNDPIS
                     LFVPPNHPFLKKEKVTIEDVGEHPLILFDYGSMDWLFIHRLFLSKGINPNIYLEVDNME
                     TAKNLVLQGLGISFLPAHCVQKEIEHNKLFRVEMDPDIKTNISIDFIYLKGKSESVFMD
                     FFKHKMFE"
     gene            8874..10046
                     /locus_tag="A4U60_RS18370"
                     /old_locus_tag="A4U60_18210"
     CDS             8874..10046
                     /EC_number="1.8.1.2"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394118.1"
                     /locus_tag="A4U60_RS18370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18210"
                     /product="sulfite reductase subunit alpha"
                     /protein_id="WP_113753818.1"
                     /transl_table=11
                     /translation="MKLTIDQTKGDKKVPVYSRTNPFQAKVLKNINLNHEGSNKETRHI
                     EFSLKDSGFSYVPGDALGIVPENDQELVAELLTEMQWDGEQVVTINKKGDTLPLKEALT
                     TYFEITLLTKKILQQAAQFTESEELKALLDAEDVSKVKEYIYGRDLLDMLRDFGPWKAS
                     AQEIVSLLRKIPPRLYSIASSLAANPDEVHLTIGVVRYTSYDRDRKGVCSVQCAERAEA
                     GDTLPIFIQPNKHFHLPESEETDIIMVGPGTGIAPFRSFIEERSVNKGSGKSWLFFGDQ
                     YSATDFLYQDELEKYQKEGVLTKLDTAFSRDTEQKVYVQHKMLENSKELYEWLQAGAYF
                     YVCGDKEYMAKDVHEALISIIEKEGNMSREEAEEQLAAMKKEKRYQRDVY"
     gene            complement(10110..11186)
                     /locus_tag="A4U60_RS18375"
                     /old_locus_tag="A4U60_18215"
     CDS             complement(10110..11186)
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002013331.1"
                     /locus_tag="A4U60_RS18375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18215"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_113753819.1"
                     /transl_table=11
                     /translation="MNEHIQLMIDWIEDKLKNEFSLDELSHYIGYSPYYCSFKFHQVTG
                     ISIRRYILLRRLYLSTVDLAKDRKIIDIAFDYDYSSQEAYSRAFKTVFGVNPREFQVNK
                     MPVQSFVKLTINKDKEWWRMNISRKMEVEQLQNEKSEFFDKYVLNILNGQVMYEEFKDK
                     KLMGDADYVPFNEAMCVNATTKHVFNEEFIKTRASGHHEPVEKYIKKVINPLDNLFNKE
                     YKCIVLWFGEDMFCQMNLLTLLSYLKQSGYDGKVFLNSFREDEFKVSQTELELGNYYAV
                     YNEVLVNHKKPSNELLPVMYQAIDIYLDMLKENNAVVKYISKNKDLPTSELMNRLFNLF
                     PTIGYGDSQYIELINKMR"
     gene            11544..12662
                     /locus_tag="A4U60_RS18380"
                     /old_locus_tag="A4U60_18220"
     CDS             11544..12662
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009847 - spore germination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394119.1"
                     /locus_tag="A4U60_RS18380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18220"
                     /product="endospore germination permease"
                     /protein_id="WP_113753820.1"
                     /transl_table=11
                     /translation="MEKAKISVIQLFALMFIFEMGTAVVTSYGINAKKDVWLAILLGMF
                     VGIVFFFVYYFLFRQYPNLPLTGYTRKIFGKYLGWIIGLLYVLYFLYSAADNIRSFGDL
                     LLSSILPNTPLLAIIILFVLTVSYVLSLGIEVVGRTAEVFIVILILLGISGNFLVLVSG
                     NVDLHNIQPFLENGWTSILTTAFLETSNFPFNQMVVFMMLLPYLNRPRLVKKVWLSALI
                     LGGLILCWTASLNIAVLGVEEVKKSTFPLLLTVGKINLFEFIQRVDVIVVFTLLITVFF
                     KASIFFYGTLIGIVDLFKLKNHQQIILPIAFILIFLSMTMASSYSEHIEEGTYVARYIT
                     IYFHVIIPLLMLLVTMIRNRFKKKGRLKSNIT"
     gene            complement(12837..13082)
                     /locus_tag="A4U60_RS18385"
                     /old_locus_tag="A4U60_18225"
     CDS             complement(12837..13082)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4U60_RS18385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4U60_18225"
                     /product="hypothetical protein"
                     /protein_id="WP_113753821.1"
                     /transl_table=11
                     /translation="MIVNFIVIKVSLRNRKRWIISGVVVSLLWAPIATTISMLIIVYYT
                     SNPFGAGAAGFAYGILLFVNGIIFLITALFSKTKGN"
     gene            13421..13582
                     /locus_tag="A4U60_RS27210"
     CDS             13421..13582
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4U60_RS27210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_172463510.1"
                     /transl_table=11
                     /translation="MKFNYDLSGHGWANGFIEMNSKRFEFRPSYLTDAFGDLLRSLVSL
                     LTHYETLR"
     gene            13613..14113
                     /locus_tag="A4U60_RS18390"
                     /old_locus_tag="A4U60_18230"
     CDS             13613..14113
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326087.1"
                     /locus_tag="A4U60_RS18390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18230"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_113753822.1"
                     /transl_table=11
                     /translation="MKLETDRLLLQALDLNLIEATAQRDTQAIEAMGYKTNGEWPDPDF
                     FEALPYFRELLIKNKGTKGFDSWIIVEKETKEIIGGIGFLGDPDPDGMIEIGFATNESQ
                     RRKGYCFEAAHKLLNWALNQKEVKCITARCQLDNINSKNVLVKLGFQVNHTDTELIYWN
                     LHK"
     gene            complement(14448..15251)
                     /locus_tag="A4U60_RS18395"
                     /old_locus_tag="A4U60_18235"
     CDS             complement(14448..15251)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012925.4"
                     /locus_tag="A4U60_RS18395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18235"
                     /product="glycoside hydrolase family 16 protein"
                     /protein_id="WP_113715698.1"
                     /transl_table=11
                     /translation="MKLFIFILIIGVIMCCTISLPITLQQKDNNHVQPIKKKTGEDKKE
                     THKSWEIVWHEDFQMFDSSKWTKLQRKGNIDELQFYLQENASYRDGKLYIIAKQKKHHG
                     QQYTSSRITTKGKFEVRYGKIEIIAKIPEGKGLFPAFWMLPSSGDELPEIDILEAIGSN
                     PYKVYYVNHWEEKTKYRSYATFKIDNVATFHKYTIIWTKNSIHWYVDGKHIFTSKQGIP
                     QEPMFFILNLAVGGTWPGNPNKHTKFPNYFIIEDLKVYKKIKSSG"
     gene            15684..16013
                     /locus_tag="A4U60_RS18400"
                     /old_locus_tag="A4U60_18240"
     CDS             15684..16013
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394121.1"
                     /locus_tag="A4U60_RS18400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18240"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_113753823.1"
                     /transl_table=11
                     /translation="MKDLTEMLKGVLEGVVLQKIQKGETYGYEITKYLNELGFDDIVEG
                     TVYTILIRIEKKGLVEIEKKKSELGPARKFYTLNAKGEQELNDFWIRWSFLAKKMNGIK
                     EQRDV"
     gene            16006..16320
                     /locus_tag="A4U60_RS18405"
                     /old_locus_tag="A4U60_18245"
     CDS             16006..16320
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003738379.1"
                     /locus_tag="A4U60_RS18405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18245"
                     /product="DUF1048 domain-containing protein"
                     /protein_id="WP_113715700.1"
                     /transl_table=11
                     /translation="MFKKMIQEKREYRAYKKRVNELPEEYKKAMKAIENYMWSFAKGSG
                     MFEVLTNILEMFESSASDGLSIREVVGNDIAEFADSFLAEFPEETWIDKLRNKLRNSIK
                     "
     gene            16332..17255
                     /locus_tag="A4U60_RS18410"
                     /old_locus_tag="A4U60_18250"
     CDS             16332..17255
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014092166.1"
                     /locus_tag="A4U60_RS18410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18250"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_113753824.1"
                     /transl_table=11
                     /translation="MNSTVLEIKNVKKSFKGNEVLKDVNITLKQGFVYALLGANGAGKS
                     TLLKIVTGLLNSDDGKVTIQDINIADNPVTAQKLFSFSSQNSTVDGVLTGYENLHLIAK
                     LRHERNPRKVAESLLEKFDLTEAKDKAVSNYSGGMRRRLDLAMSLVGNPEIIFLDEPTT
                     GLDPKSRQDLWDTIKEMKLQGKTIFLTTQYLEEADYLADQIGFLREGKIVASGTPDEMK
                     RIAGVDKLLLVFNRNEDTDIALKLLESYSSEKKDNCEISIDLTEDITTTLNVLNALTTE
                     NIELKTFKMITPTLDDVFMTLTRGRK"
     gene            17255..18022
                     /locus_tag="A4U60_RS18415"
                     /old_locus_tag="A4U60_18255"
     CDS             17255..18022
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007475573.1"
                     /locus_tag="A4U60_RS18415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18255"
                     /product="ABC transporter permease"
                     /protein_id="WP_113753825.1"
                     /transl_table=11
                     /translation="MKIRQNAGDTLALANRIIKHNLRSIDTLITVIAMPVMMLLGMVYI
                     FGGAIQIPGVSQEDYINYVLPGILLMTIATGSAYTSLRINLDKTSGMFDRFKSMPISKS
                     SVLGGHVLASVVFMLVSIIAVLLVGFLAGFRSNATFSEWLLVVVMIILFSLALTWLSVP
                     FALAAGSIEGAGSFSYILLMMLFVSSAFVPVDGMPKIVGLFAENQPMTPIIQTIRNLLN
                     SQAAGNNLWVSIGWMVLIIMISYIFGMKAYRRV"
     gene            complement(18237..>18524)
                     /locus_tag="A4U60_RS18420"
                     /old_locus_tag="A4U60_18260"
                     /pseudo=""
     CDS             complement(18237..>18524)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016124259.1"
                     /locus_tag="A4U60_RS18420"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="A4U60_18260"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="HIEQYLEKVVKQNYEGIFLVGKTPKKSPSKKKIAILKGIHHSFRW
                     FSIKM"
     misc_feature    18954..18967
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.99"
                     /tool="antismash"
     gene            18990..19967
                     /locus_tag="A4U60_RS18425"
                     /old_locus_tag="A4U60_18265"
     CDS             18990..19967
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290962.1"
                     /locus_tag="A4U60_RS18425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18265"
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_113753826.1"
                     /sec_met_domain="PF00881 (E-value: 3.2e-24, bitscore: 79.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQIYYWSPIKHWEKFSNEVLIGETRYTGVMSEWFPEFYFLAQK
                     GMTISQLLERFSLGNEEEAQKIVELMIKNRVLVSNILPPREVFSTQEKIFPNPYSDQIR
                     FSKDNLDKYISEQLNRMHPAARSTGIQLETKDELPNIIRERRSCRQFDMKNPVPFSEFA
                     QLFSTFKQRKEEKIYYHYASAGGVYPIDIFVYIKPKRVEDIKAGFYYYSPSENSLLFVN
                     NIDQVIKSDHEIINQELFNQSAFSIYLVYNAHASMPKYGSDGYLFACIESGIITATLNM
                     VAETLNLGVCSVGHMKFEDIHRFLSLDNHQVFLHGIEVGLKISE"
     gene            20001..27011
                     /locus_tag="A4U60_RS18430"
                     /old_locus_tag="A4U60_18270"
     CDS             20001..27011
                     /NRPS_PKS="Domain: AMP-binding (266-656). E-value:
                     5.7e-110. Score: 359.6. Matches aSDomain:
                     nrpspksdomains_A4U60_RS18430_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (762-828). E-value: 2.7e-20. Score:
                     64.3. Matches aSDomain: nrpspksdomains_A4U60_RS18430_PCP.1"
                     /NRPS_PKS="Domain: Heterocyclization (847-1144). E-value:
                     1.6e-88. Score: 288.9. Matches aSDomain:
                     nrpspksdomains_A4U60_RS18430_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (1303-1683). E-value:
                     2.3e-99. Score: 324.7. Matches aSDomain:
                     nrpspksdomains_A4U60_RS18430_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1789-1856). E-value: 5.1e-20.
                     Score: 63.4. Matches aSDomain:
                     nrpspksdomains_A4U60_RS18430_PCP.2"
                     /NRPS_PKS="Domain: Condensation_DCL (1903-2202). E-value:
                     7.5e-85. Score: 276.6. Matches aSDomain:
                     nrpspksdomains_A4U60_RS18430_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547618.1"
                     /locus_tag="A4U60_RS18430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18270"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_113753827.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-113, bitscore:
                     373.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-11, bitscore:
                     38.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.3e-69, bitscore:
                     226.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYIKDLSSIHEYKGAESFWKEQLSSDVPDFSLFNSGYQMNKDNLC
                     DHVQVIMDVEFSQSLQKVSKSQDLFLFNWLQAALRVCLVHYTDQERIIIGVPVIEKDHE
                     QRENLNDLLPIGTEIHSLHSFKQVVEQVQQTTLLGYENQHYPLSELLAKLYSTPFQIVL
                     GMEGLHNKNSLEECSENELAIWIQRKENEKHNEFEFQISCKSHSLFPLQQFAKSYLYVL
                     KQVLKNPDLAVKDICIISEEEKELLEGFNQVQLGINLSQTFQDLFEKQVLKTPDQIAVV
                     CNNQSLTYRELNKKANQLASVLQSKGVSKESIIGVMVDRSVEMIIGMMGILKARGAYLP
                     IDPYYPNERIEYMLQDSQAKWLLSKRTEKELPQFAGEVLYLDEEHLFQGEESNINRESE
                     PNDLAYVIYTSGSTGNPKGVMVEQRSLVHFLSIMSEKLKDNQSFLFLASVSFDISLLEI
                     CVPLTQGSKVVIATEGQFVTKELAHLIKEHKVDLWESTPSRMELILSDPEGAEFLRDLK
                     FILLAGEAFSIDLIEKIRSISKAQILNIYGPTETTICAAVKDLSTAKEVTIGKPNPNYY
                     SYVLNKYSQMKPWGIPGELCISGAAVARGYLGKSKLTDEKFVPNPFVAGEMMYRTGDLV
                     RWLPNGELEYLGRMDHQVKIRGYRIELGEIEAELKRHPEIGQAIVVDQIDGNRKSLAAY
                     YGSDKKIPFEELRKYLSNKLPEFMIPEKIIQVKEIPLNPNGKVDRKRLLDLTQIDQISI
                     PYVAPRNQIEQKLVQAWEKVMEIERIGIHDHFFALGGESIKALQIINLLGKDHLKVSTR
                     DIFKYPTIAQLSSCVEVEQKEESLDKTPIRVKDLSKPFSLTEVQTAYMLGRNSQFELSG
                     ISPQTYFEYETKLDINRLSQSLQKVIQRHSMLRAVILPEGKQQILQDVPDYQIEIENLI
                     GLDEGKQNVRLQEERSRMTNHVFPLGQWPLFELKAFLLKEDTYLLCFRYDALLMDGASM
                     NIVGHDLLHYYHKPDQRLESLSFDFQDYMCIYDEMEQSKEYKKAKDYWTNKLPDFPFAP
                     SLLLKKDPEEIATPNFQSLTKILDKDKWTKLRKLAQEKEVTPSALLCTLYGEVLAYWSN
                     QRRLAINLTVFNRYPVHEEVEQIVGDFTSLILLDVDVNPERSFFTRVEKTQSTLLDGLE
                     HRHYDGVSFIRDFTRYHQMRPKAVMPIVFTSMLAGAGAFAWEQLGSLRHIHARTPQVYL
                     DNVVIEKNGELLISWNYVEELFDVDVMEAMFSQFVDLLEQLVKQRDVTSLQVKKSDQSL
                     IEQYNQTTEKILSTTLYQLFADQVKRTPDQVAVVFEQEWLTYLDLHQRSNQVAHYLQEQ
                     GISLGDRVGLLAQRRVDTIVNMIGILKAGAAYVPIDPDHPPDRQTYILENSSCKLLLEP
                     GLYKEKHLSSYATEDLPSIAGLEDIAYIIYTSGSTGKPKGVIITHQAVSNTIQDINQKY
                     QVNEDDRIIGISSMCFDLSVYDIFGALSTGAMLVMIRDPRDMQELIRTVERRGITIWNT
                     VPAIMDLAVDQVGSHFENASLRLVLLSGDWIPLPLPEKIKRHFPIAEVISLGGATEASI
                     WSIYYPVKQVEAHWNSIPYGTPLANQTYYVLNYDKKMCPVGVIGDLYIGGVGLAQGYLN
                     DEQKTNEVFVSHPDLGLIYKTGDCGRMHPEGYIEFLGRYDYQVKIQGYRVELEEIAHCL
                     LTYKQVDQAVVIDQTDENEIKFLVAYVVTEQDISTTELRKYLRDHLPEYMIPSYFVYLE
                     RLPLTPNGKLDRKALPAPEKQKNEVYIAPKTEMEKRLTSVWQEVLKVDQIGVNDHFFAL
                     GGDSIKAIQVSGRLYVQGFQLDPKSLFDFPVFDDMIHSIKRIDRPSHSQTDDINKKKEN
                     KVISLNVRDKQLNQHTLNKIQEKMPDLKIERIYPLAPFQQVIYEHAVIEPDTNAYFEQT
                     IWTLEGRLDVDLFIQCFQQLVDRHDSLRTIIMRDEQEQPWQAVLHDVQMISEVQSLTEM
                     TRQEQQECLDQWMSENLGRGFNNDELMTRLCVFQLKNNEYKVVWSAHHLLCDGWSVSIL
                     LDELFQLYEAKNAGTKVELPPVKPFQTFIDWTLAQDYEKARRFWRDYLSGYNRKISIPK
                     KKVPTQSKGLSFTFLDLTLDEDLTNQLRTFVTQHHVTMNSALLAVWGILLGKYNGTKEV
                     VLPNLVSVRPPEVEGIENMFGLFTNVLPIRVAWEETQSFVDLLQKVQQETLKCNEYAYY
                     SLVEIQKQSELTDQLTDHLWVFENYPTNPSIFSSNENRNFTITDYEVVDEPHVKYGIIC
                     FPEEKLTMKFGYDQNIYEAEQVQEILNHLHALIKTIVYNPTQTIGDYQL"
     aSDomain        20799..21968
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS18430_AMP-binding.1"
                     /evalue="5.70E-110"
                     /label="A4U60_RS18430_AMP-binding.1"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="656"
                     /protein_start="266"
                     /score="359.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEKQVLKTPDQIAVVCNNQSLTYRELNKKANQLASVLQSKGVSKE
                     SIIGVMVDRSVEMIIGMMGILKARGAYLPIDPYYPNERIEYMLQDSQAKWLLSKRTEKE
                     LPQFAGEVLYLDEEHLFQGEESNINRESEPNDLAYVIYTSGSTGNPKGVMVEQRSLVHF
                     LSIMSEKLKDNQSFLFLASVSFDISLLEICVPLTQGSKVVIATEGQFVTKELAHLIKEH
                     KVDLWESTPSRMELILSDPEGAEFLRDLKFILLAGEAFSIDLIEKIRSISKAQILNIYG
                     PTETTICAAVKDLSTAKEVTIGKPNPNYYSYVLNKYSQMKPWGIPGELCISGAAVARGY
                     LGKSKLTDEKFVPNPFVAGEMMYRTGDLVRWLPNGELEYLGRMDHQVKIR"
     aSModule        20799..22484
                     /complete
                     /domains="nrpspksdomains_A4U60_RS18430_AMP-binding.1"
                     /domains="nrpspksdomains_A4U60_RS18430_PCP.1"
                     /locus_tags="A4U60_RS18430"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20985..21026
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0001"
                     /evalue="1.60E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="342"
                     /protein_start="328"
                     /score="12.0"
                     /tool="antismash"
                     /translation="MGILKARGAYLPID"
     CDS_motif       21210..21266
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0002"
                     /evalue="3.80E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="422"
                     /protein_start="403"
                     /score="31.6"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGNPKGVMVE"
     CDS_motif       21762..21851
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0003"
                     /evalue="4.70E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="617"
                     /protein_start="587"
                     /score="38.1"
                     /tool="antismash"
                     /translation="PWGIPGELCISGAAVARGYLGKSKLTDEKF"
     CDS_motif       21933..21998
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0004"
                     /evalue="9.90E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="666"
                     /protein_start="644"
                     /score="39.9"
                     /tool="antismash"
                     /translation="YLGRMDHQVKIRGYRIELGEIE"
     aSDomain        22287..22484
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS18430_PCP.1"
                     /evalue="2.70E-20"
                     /label="A4U60_RS18430_PCP.1"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="828"
                     /protein_start="762"
                     /score="64.3"
                     /tool="antismash"
                     /translation="EQKLVQAWEKVMEIERIGIHDHFFALGGESIKALQIINLLGKDHL
                     KVSTRDIFKYPTIAQLSSCVE"
     aSDomain        22542..23432
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS18430_Heterocyclization.
                     1"
                     /evalue="1.60E-88"
                     /label="A4U60_RS18430_Heterocyclization.1"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1144"
                     /protein_start="847"
                     /score="288.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DALLMDG"
                     /tool="antismash"
                     /translation="KPFSLTEVQTAYMLGRNSQFELSGISPQTYFEYETKLDINRLSQS
                     LQKVIQRHSMLRAVILPEGKQQILQDVPDYQIEIENLIGLDEGKQNVRLQEERSRMTNH
                     VFPLGQWPLFELKAFLLKEDTYLLCFRYDALLMDGASMNIVGHDLLHYYHKPDQRLESL
                     SFDFQDYMCIYDEMEQSKEYKKAKDYWTNKLPDFPFAPSLLLKKDPEEIATPNFQSLTK
                     ILDKDKWTKLRKLAQEKEVTPSALLCTLYGEVLAYWSNQRRLAINLTVFNRYPVHEEVE
                     QIVGDFTSLILLDVDV"
     aSModule        22542..25568
                     /complete
                     /domains="nrpspksdomains_A4U60_RS18430_Heterocyclization.1"
                     /domains="nrpspksdomains_A4U60_RS18430_AMP-binding.2"
                     /domains="nrpspksdomains_A4U60_RS18430_PCP.2"
                     /locus_tags="A4U60_RS18430"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       22641..22721
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0005"
                     /evalue="2.50E-08"
                     /label="C2_DCL_024-062"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="907"
                     /protein_start="880"
                     /score="26.2"
                     /tool="antismash"
                     /translation="ETKLDINRLSQSLQKVIQRHSMLRAVI"
     CDS_motif       22944..23000
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0006"
                     /evalue="1.30E-03"
                     /label="C3_DCL_135-156"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1000"
                     /protein_start="981"
                     /score="11.4"
                     /tool="antismash"
                     /translation="LLMDGASMNIVGHDLLHYY"
     CDS_motif       23262..23318
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0007"
                     /evalue="3.40E-09"
                     /label="Cy4"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1106"
                     /protein_start="1087"
                     /score="29.3"
                     /tool="antismash"
                     /translation="VTPSALLCTLYGEVLAYWS"
     CDS_motif       23334..23369
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0008"
                     /evalue="3.40E-03"
                     /label="afterCy4"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1123"
                     /protein_start="1111"
                     /score="10.3"
                     /tool="antismash"
                     /translation="AINLTVFNRYPV"
     CDS_motif       23370..23429
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0009"
                     /evalue="5.00E-09"
                     /label="Cy5"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1143"
                     /protein_start="1123"
                     /score="28.2"
                     /tool="antismash"
                     /translation="HEEVEQIVGDFTSLILLDVD"
     CDS_motif       23493..23534
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0010"
                     /evalue="1.30E-03"
                     /label="afterCy5"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1178"
                     /protein_start="1164"
                     /score="11.7"
                     /tool="antismash"
                     /translation="LEHRHYDGVSFIRD"
     CDS_motif       23655..23699
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0011"
                     /evalue="2.50E-03"
                     /label="Cy7"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1233"
                     /protein_start="1218"
                     /score="11.1"
                     /tool="antismash"
                     /translation="RTPQVYLDNVVIEKN"
     aSDomain        23910..25049
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS18430_AMP-binding.2"
                     /evalue="2.30E-99"
                     /label="A4U60_RS18430_AMP-binding.2"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1683"
                     /protein_start="1303"
                     /score="324.7"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FADQVKRTPDQVAVVFEQEWLTYLDLHQRSNQVAHYLQEQGISLG
                     DRVGLLAQRRVDTIVNMIGILKAGAAYVPIDPDHPPDRQTYILENSSCKLLLEPGLYKE
                     KHLSSYATEDLPSIAGLEDIAYIIYTSGSTGKPKGVIITHQAVSNTIQDINQKYQVNED
                     DRIIGISSMCFDLSVYDIFGALSTGAMLVMIRDPRDMQELIRTVERRGITIWNTVPAIM
                     DLAVDQVGSHFENASLRLVLLSGDWIPLPLPEKIKRHFPIAEVISLGGATEASIWSIYY
                     PVKQVEAHWNSIPYGTPLANQTYYVLNYDKKMCPVGVIGDLYIGGVGLAQGYLNDEQKT
                     NEVFVSHPDLGLIYKTGDCGRMHPEGYIEFLGRYDYQVKI"
     CDS_motif       24099..24137
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0012"
                     /evalue="2.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1379"
                     /protein_start="1366"
                     /score="17.7"
                     /tool="antismash"
                     /translation="GILKAGAAYVPID"
     CDS_motif       24282..24341
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0013"
                     /evalue="2.80E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1447"
                     /protein_start="1427"
                     /score="32.0"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVIITH"
     CDS_motif       24852..24941
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0014"
                     /evalue="6.60E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1647"
                     /protein_start="1617"
                     /score="44.0"
                     /tool="antismash"
                     /translation="PVGVIGDLYIGGVGLAQGYLNDEQKTNEVF"
     CDS_motif       25017..25079
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0015"
                     /evalue="5.90E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1693"
                     /protein_start="1672"
                     /score="25.1"
                     /tool="antismash"
                     /translation="FLGRYDYQVKIQGYRVELEEI"
     aSDomain        25368..25568
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS18430_PCP.2"
                     /evalue="5.10E-20"
                     /label="A4U60_RS18430_PCP.2"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1856"
                     /protein_start="1789"
                     /score="63.4"
                     /tool="antismash"
                     /translation="EKRLTSVWQEVLKVDQIGVNDHFFALGGDSIKAIQVSGRLYVQGF
                     QLDPKSLFDFPVFDDMIHSIKR"
     aSDomain        25710..26606
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS18430_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="7.50E-85"
                     /label="A4U60_RS18430_Condensation_DCL.1"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="2202"
                     /protein_start="1903"
                     /score="276.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLLCDG"
                     /tool="antismash"
                     /translation="ERIYPLAPFQQVIYEHAVIEPDTNAYFEQTIWTLEGRLDVDLFIQ
                     CFQQLVDRHDSLRTIIMRDEQEQPWQAVLHDVQMISEVQSLTEMTRQEQQECLDQWMSE
                     NLGRGFNNDELMTRLCVFQLKNNEYKVVWSAHHLLCDGWSVSILLDELFQLYEAKNAGT
                     KVELPPVKPFQTFIDWTLAQDYEKARRFWRDYLSGYNRKISIPKKKVPTQSKGLSFTFL
                     DLTLDEDLTNQLRTFVTQHHVTMNSALLAVWGILLGKYNGTKEVVLPNLVSVRPPEVEG
                     IENMFGLFTNVLPIRVAW"
     CDS_motif       25782..25889
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0016"
                     /evalue="5.80E-16"
                     /label="C2_DCL_024-062"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="1963"
                     /protein_start="1927"
                     /score="50.8"
                     /tool="antismash"
                     /translation="AYFEQTIWTLEGRLDVDLFIQCFQQLVDRHDSLRTI"
     CDS_motif       26115..26177
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0017"
                     /evalue="9.50E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="2059"
                     /protein_start="2038"
                     /score="34.1"
                     /tool="antismash"
                     /translation="HHLLCDGWSVSILLDELFQLY"
     CDS_motif       26433..26471
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0018"
                     /evalue="9.00E+00"
                     /label="Cy4"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="2157"
                     /protein_start="2144"
                     /score="-0.2"
                     /tool="antismash"
                     /translation="HVTMNSALLAVWG"
     CDS_motif       26523..26597
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0019"
                     /evalue="5.80E-09"
                     /label="C5_DCL_263-294"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="2199"
                     /protein_start="2174"
                     /score="28.4"
                     /tool="antismash"
                     /translation="VSVRPPEVEGIENMFGLFTNVLPIR"
     CDS_motif       26646..26762
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18430_0020"
                     /evalue="2.20E-11"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="A4U60_RS18430"
                     /protein_end="2254"
                     /protein_start="2215"
                     /score="36.1"
                     /tool="antismash"
                     /translation="QQETLKCNEYAYYSLVEIQKQSELTDQLTDHLWVFENYP"
     gene            27067..28521
                     /locus_tag="A4U60_RS18435"
                     /old_locus_tag="A4U60_18275"
     CDS             27067..28521
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Beta_elim_lyase (137-314). E-value:
                     3.1e-09. Score: 28.4. Matches aSDomain:
                     nrpspksdomains_A4U60_RS18435_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016113469.1"
                     /locus_tag="A4U60_RS18435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18275"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_113715705.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-08, bitscore:
                     27.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSENLQLSAEKMRQLGYQAVDLIIDHMNHLKSKPVSEAIDSDILR
                     KKLTESIPENGADPKELLHFLTRNVFNQITHVDHPHFLAFVPGPSNYVGVVADFLASGF
                     NVFPTAWIAGAGAEQIELTTINWLKSMLGFPDSAEGLFVSGGSMANLTALTVARQVKLN
                     NDIENAVVYFSDQTHFSVDRALKVLGFKHHQICRIETDEHLRISVSALKKQLKEDRTKG
                     KKPFCVIANAGTTNCGAVDSLNELADLCNDEDVWLHADGAYGAPAILSEKGSALLLGIH
                     RVDSLTLDPHKWLFQPYDVGCVLIRNSQYLSKTFRMIPEYIKDSETNIEEEINFGECGI
                     ELSRRFRALKVWLSFKVFGVEAFRQAIDHGIMLAEQVETFLGKAKDWEVVTPAQLGIVT
                     FRYIPCELASTDTINEINKKLVGEITRRGFAMLSTTELKEKVVIRLCSINPRMTTEEML
                     QIIMKIKALAEEVRTSYEHLISVPKL"
     aSDomain        27478..28008
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS18435_Beta_elim_lyase.1"
                     /evalue="3.10E-09"
                     /label="A4U60_RS18435_Beta_elim_lyase.1"
                     /locus_tag="A4U60_RS18435"
                     /protein_end="314"
                     /protein_start="137"
                     /score="28.4"
                     /tool="antismash"
                     /translation="AEGLFVSGGSMANLTALTVARQVKLNNDIENAVVYFSDQTHFSVD
                     RALKVLGFKHHQICRIETDEHLRISVSALKKQLKEDRTKGKKPFCVIANAGTTNCGAVD
                     SLNELADLCNDEDVWLHADGAYGAPAILSEKGSALLLGIHRVDSLTLDPHKWLFQPYDV
                     GCVLIRNSQYLSKT"
     gene            complement(28724..30271)
                     /locus_tag="A4U60_RS18440"
                     /old_locus_tag="A4U60_18280"
     CDS             complement(28724..30271)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002107059.1"
                     /locus_tag="A4U60_RS18440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18280"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_113753828.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.2e-18, bitscore:
                     58.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKLHDVIVVGAGPGGLQVALSLKELSDEYNQKLDLLMIESGKQA
                     GAFYTKYPVHGQLISNNKLYTGKPPKSRFSERFDWNSLLTKEKKIMMRNYSREFFPRRE
                     ALVEMLNDLVAEYELPVMYNTMWKATRKTEQGYFEVETDNGKLYSKFLVIATGMTPNPP
                     PIPGLEHTTPYHEMKKKEHYRDKRVLIIGKGNSGMECVQEILNEANLIMVASRHSTRMA
                     YKTHYVGDVRAVNSLLVDNYQLKHQAALLDCEVLNIEKVDEGFNVTVHYKHAEDEKEVL
                     FFNEIIAATGFRSNIDHLVKDLNLKIINKKYPSISGVFESTEVSNLFFAGTQTHGLDYR
                     KTSSGFIHGFRYNSKVLAYKIADRLEFPIKNLMISNEEVVGHILGELTEASDPYLQPGF
                     IVYVMKYEAGMWNIFGYQTIIEFENAPLQEDEVLLAASLEYGDIHKFADPLNIPRVPGQ
                     PEESVHIHPVVRVRKGENAIEKLDLEEHLENQFMDLPTYHQPLSEFLKAILGTKINI"
     gene            complement(30299..31585)
                     /locus_tag="A4U60_RS18445"
                     /old_locus_tag="A4U60_18285"
     CDS             complement(30299..31585)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013188.4"
                     /locus_tag="A4U60_RS18445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18285"
                     /product="cation:proton antiporter"
                     /protein_id="WP_113715707.1"
                     /transl_table=11
                     /translation="MGSNMELFLSFIPALILVLVASYICGNLARYIGQPKVVGEMIAGI
                     LIGPSFLGIFAPQFMSFLFTTDIKSILYVLSNIGLGMYMFLVGAEVDEKKLTGNLIKKC
                     TILSTSGIIVPLLLGIMVGILYYSKLSLPNVNIYLFALFIGSALSLTAFPMLARILQER
                     NLTTSHFGTLALIAASIDDALAWCLVALITALAQAQGVLAGITAITFGALFACFMLLIG
                     KKWLTRLGERVEKEGSLSMNHFSLVLLLLLVAIWFTDYVGVYSVFGGFIVGLSMPRNKV
                     FLQELQSKFQPFVITLLLPIFFAYSGLNTNFTTIFNDMSLLIPAMVVLVASIAGKYGGC
                     ALAMKSIGYSWREASAIGMLMNARGLMVLILVNIGMTYKIITPQVFAILVLMTLVTTIM
                     AMPIFNIFYPENPKENQNVLDLKPFSKQS"
     cand_cluster    30451..60324
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    30451..60324
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[40450:50324](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      40451..50324
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
     misc_feature    32054..32068
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 22.96"
                     /tool="antismash"
     misc_feature    complement(32433..32453)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 23.81"
                     /tool="antismash"
     misc_feature    32503..32521
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: medium, score: 30.39"
                     /tool="antismash"
     misc_feature    32518..32534
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.93"
                     /tool="antismash"
     gene            32612..33067
                     /locus_tag="A4U60_RS18450"
                     /old_locus_tag="A4U60_18290"
     CDS             32612..33067
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018782499.1"
                     /locus_tag="A4U60_RS18450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18290"
                     /product="VOC family protein"
                     /protein_id="WP_113753829.1"
                     /transl_table=11
                     /translation="MIKGIYEAHLPVKDLENSIDFYRRLGLELAWHDEFTAFFWVDKGR
                     SWLGLWEGDEYKTPYHPALRHIAFEVTYEDLKTSVEWLNTLGIKAEPVNPNQPIDPFIR
                     PNQGNGTVYFNDPDGNSLELMCYIEVPEHLRHITNKLSFSEWEEINK"
     misc_feature    33116..33136
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 23.31"
                     /tool="antismash"
     gene            33274..33960
                     /locus_tag="A4U60_RS18455"
                     /old_locus_tag="A4U60_18295"
     CDS             33274..33960
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002144049.1"
                     /locus_tag="A4U60_RS18455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18295"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_113753830.1"
                     /transl_table=11
                     /translation="MKIIELPIEYEFHRQKNCIYPSLIILNNELTLVDTGYTNFLTLIE
                     NEILKNGYEMKNLKNIIITHYDDDHIGSLYDFKEKYPWITIIASEIESKYISGELKAER
                     LVQAEEMLENMSNEDMEFGKWFIQQLKNLKPVLINKKVHDGDMILDNECRVVATPGHTS
                     GHISLYFPRLKSIITGDAAVKENHELVIANPQFCLNIEKSQQSLIKIKNLKAENYYCYH
                     GGKFTL"
     misc_feature    complement(33297..33311)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.4"
                     /tool="antismash"
     gene            34092..35069
                     /locus_tag="A4U60_RS18460"
                     /old_locus_tag="A4U60_18300"
     CDS             34092..35069
                     /NRPS_PKS="Domain: PKS_ER (19-314). E-value: 4.4e-28.
                     Score: 90.2. Matches aSDomain:
                     nrpspksdomains_A4U60_RS18460_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394125.1"
                     /locus_tag="A4U60_RS18460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18300"
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_113753831.1"
                     /sec_met_domain="ADH_N (E-value: 4.3e-11, bitscore: 36.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.3e-14, bitscore:
                     46.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLKGICIKYYEFGNPSDVLRIEEVDVPLPQEGELLVKMEMSPIN
                     PSDIIPITGAYANRITVPSIPGYEGVGIVEDVGPSVSKWFIGKRVLPLRGQGTWQEFVT
                     SPAELAIVLPEDIHNHIAAQLYINPITAWVICNQVLKLKPDDILLVNACGSSIGRIFVQ
                     LSQIIGFQLIAITRNDKHTASLLEIGASYVINTEVTSLKEAVMDLTRGRGATAAIDSIG
                     GIEGTHLAFCLQPKGILLSIGLLSGVPLNYREIMERTQTQAEIFHLRHWNKNISVKEWH
                     ATFYQLIQMIRDDTLQLSQISQSFSLANVHRALTESRKVFLTMN"
     aSDomain        34149..35033
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS18460_PKS_ER.1"
                     /evalue="4.40E-28"
                     /label="A4U60_RS18460_PKS_ER.1"
                     /locus_tag="A4U60_RS18460"
                     /protein_end="314"
                     /protein_start="19"
                     /score="90.2"
                     /tool="antismash"
                     /translation="LRIEEVDVPLPQEGELLVKMEMSPINPSDIIPITGAYANRITVPS
                     IPGYEGVGIVEDVGPSVSKWFIGKRVLPLRGQGTWQEFVTSPAELAIVLPEDIHNHIAA
                     QLYINPITAWVICNQVLKLKPDDILLVNACGSSIGRIFVQLSQIIGFQLIAITRNDKHT
                     ASLLEIGASYVINTEVTSLKEAVMDLTRGRGATAAIDSIGGIEGTHLAFCLQPKGILLS
                     IGLLSGVPLNYREIMERTQTQAEIFHLRHWNKNISVKEWHATFYQLIQMIRDDTLQLSQ
                     ISQSFSLANVHRAL"
     misc_feature    35139..35156
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.87"
                     /tool="antismash"
     gene            35664..35831
                     /locus_tag="A4U60_RS27215"
     CDS             35664..35831
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4U60_RS27215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_172463511.1"
                     /transl_table=11
                     /translation="MDNLIKLSKIYAITPDELVKEEQISWKKATIDEEGEEFSILPFII
                     GFIILLVGFF"
     gene            complement(35994..37073)
                     /locus_tag="A4U60_RS18465"
                     /old_locus_tag="A4U60_18305"
     CDS             complement(35994..37073)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394127.1"
                     /locus_tag="A4U60_RS18465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18305"
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="WP_113753832.1"
                     /transl_table=11
                     /translation="MTTYRLGVLAGDGIGPEIVSATVDAFKTAADKVGVDIDWIDLPMG
                     WEGIKQYNDPLPEFTTNALKDTHGWILGPHDSAAYPLEHKVKLNPSGALRHTLDLFANI
                     RPAKTMPGIKSVVGEADLVIFRENTEGFYADRNMFAGHGEWQITEDVVVTSGVFTRKAV
                     ERIAHAAFKMAMKRRKKVTIVHKANVLRLSTGLFLNVCREVAKQYPEVTVDDYHIDAMA
                     AHLVRRAKEFDVIVTENMYGDILSDLAGELVGSLGLAPSINANATVAMAQAAHGSAPDI
                     AGLNIGNPTGMMLSTVMLMEWLAERHNDNNLEEIGKLVEQSLYHSLKDGITTKDLGGNA
                     STSEFAKAISERINQIFVN"
     gene            37706..37846
                     /locus_tag="A4U60_RS18475"
                     /old_locus_tag="A4U60_18315"
     CDS             37706..37846
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF028352.4"
                     /locus_tag="A4U60_RS18475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18315"
                     /product="hypothetical protein"
                     /protein_id="WP_242447720.1"
                     /transl_table=11
                     /translation="MLKEIETGLPSGLTIGRHMLIVLKSDRFGGEEFLSLAIKHLRNLS
                     H"
     misc_feature    37923..37939
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.89"
                     /tool="antismash"
     misc_feature    37998..38014
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 25.05"
                     /tool="antismash"
     gene            38136..38801
                     /locus_tag="A4U60_RS18480"
                     /old_locus_tag="A4U60_18320"
     CDS             38136..38801
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394136.1"
                     /locus_tag="A4U60_RS18480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18320"
                     /product="cyclase family protein"
                     /protein_id="WP_113753833.1"
                     /transl_table=11
                     /translation="MKRKKYIDLSHTIQDGIITYKGLPAPIICDYLSREESRKHYGEGT
                     EFQIGKIEMVSNTGTYIDVPFHRYANGKDLSEIPIDKMAGLEGIIVHIDENKKEINEDV
                     FYNLDIEGKAVLIHTGWDQYWNTDQYFENHPYLTEKAAQYLVDKRAALVGIDSVNIDDT
                     SGKDRPVHTTLLGQEILIVEHLCNLKQISTENFLFYAVSPKIKDFGTFPVRAFVEISN"
     gene            39200..40024
                     /locus_tag="A4U60_RS18490"
                     /old_locus_tag="A4U60_18330"
     CDS             39200..40024
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394139.1"
                     /locus_tag="A4U60_RS18490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18330"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_113753834.1"
                     /transl_table=11
                     /translation="MKNSNNDIQDMIHYVKGKREVFQQKLLSEAVNVAEVINDILKQGN
                     IDLLKNAEKLVVYILENNDQDIVAFARQEGVAWAQHSLTLAFKLEWVQAIRRSLWKTIY
                     EYQSEFNLPSIREDFFELEKRINNNIDQFLNTFFLSYSDFKDQLIHRQRKNVEHLSVPI
                     IPISPTVAILPLIGTIDSYRMDTIEEKVLTDIARTRIHTLIMDLSGITDMEVVVIDHFH
                     KVLDGINMMGCKAVITGLRPELVREMIHLGINFNQKAITKGTLQQSLKDYLL"
     misc_feature    complement(40088..40102)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.47"
                     /tool="antismash"
     misc_binding    40152..40393
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     gene            40451..42019
                     /locus_tag="A4U60_RS18495"
                     /old_locus_tag="A4U60_18335"
     CDS             40451..42019
                     /EC_number="2.3.3.13"
                     /GO_function="GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018392748.1"
                     /locus_tag="A4U60_RS18495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18335"
                     /product="2-isopropylmalate synthase"
                     /protein_id="WP_113753835.1"
                     /sec_met_domain="HMGL-like (E-value: 3.3e-92, bitscore:
                     302.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKKILVFDTTLRDGEQVPGAKLNLYEKLEVAQQLKRLQVDIIEV
                     GFPSSSTGDFNAVKEIAMKVGNTDEIMITALARAVKSDIDAVYNSVKYAKNPLIHIVLG
                     TSDIHVEKKFGKSKSQILDIGVDAVKYAKTLLPDVQYSTEDASRSDFEYLWSTIEAVVK
                     AGATIINVPDTVGYAEPEEFGELIFKLNDRLKNLNDKILLSVHCHNDLGMATANTLAAI
                     KNGADKVECTINGIGERAGNAALEEVVMAVNTRSSVYKAFTNINTKEIMNTSRLVSSFM
                     GLDVQVNKAITGDNAFAHSSGIHQDGLLKSRDAYEIISPFEVGLDDMELILTARSGRHA
                     VKNALKKLGFNQLTETQLEGIFEAFLELADTKKEVYNHDLYVLVENYYTRHNIHNQGMV
                     HYSDNFYELMDIQVISNPIFPSASVKIKKANQILKSSAVGSGPIDALYSAITEISDLDI
                     KLIEYNISSVSRGKEALGKVKIQVEYKGEKYTAKATDTDIMKASALAYINVINIILVDS
                     LLPIK"
     gene            42300..42896
                     /locus_tag="A4U60_RS18500"
                     /old_locus_tag="A4U60_18340"
     CDS             42300..42896
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003183757.1"
                     /locus_tag="A4U60_RS18500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18340"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_113753836.1"
                     /transl_table=11
                     /translation="MENNVFEQMAKRYDTEERMELAKIIVKEVRTELPNSKSKSLIDYG
                     SGTGLIGLELSDLVDSILLVDSSKQMLEVAKAKISQKEITNSKVLYSDFTQGTPDLKAD
                     IVLMSLVLLHIPDTKKILQELFNVLNDEGKLIIIDFDKNHKINHSKVHNGFLDKELKKM
                     LSEVGFKSIKIKTFYHSNRIFMNQDASMFISSSIK"
     gene            complement(43199..43645)
                     /locus_tag="A4U60_RS18505"
                     /old_locus_tag="A4U60_18345"
     CDS             complement(43199..43645)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394141.1"
                     /locus_tag="A4U60_RS18505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18345"
                     /product="RDD family protein"
                     /protein_id="WP_113753837.1"
                     /transl_table=11
                     /translation="MSHVIKPAGFWIRFLGNLLDGVIVSIPLTLIVFLLTGEFNENDPV
                     ISILGVIYTVAVPILWSGYTIGKRIVGVRIVKVNGKKLGIGAMLLRVLVAGIVYSLTLG
                     IALIVSLFMVVFRKDKRSLHDLMAGTYVTYAKPDEMEDKHTAAS"
     gene            44427..45566
                     /locus_tag="A4U60_RS18510"
                     /old_locus_tag="A4U60_18350"
     CDS             44427..45566
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422145.1"
                     /locus_tag="A4U60_RS18510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18350"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_113753838.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.3e-37, bitscore:
                     121.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5e-28, bitscore:
                     90.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.2e-56, bitscore:
                     183.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFDLTKEQEMIRKLIRDFSEAEVAPGADERDRTGAFPYEMFSKL
                     AELGIMGLPFPEQYGGGDADTISFAIVVEELSRVCASSGITYSAHISLGGEPLNLFGTH
                     EQKEKYLTPICTGESFGAFGLTEPNAGSDAGGTQTTAVIDGEEWVINGSKCFITNASYA
                     KHLAVTAVTDRSKGINGISAFIVPTNAPGFTVINNYEKMGLQSSNTTELILENVRVTKD
                     NLLGTAGEGFKQFLATLDGGRIGIGAMAVGLAQGAYEKSLQYAKERKQFGKSISNFQAI
                     QFKLADMAMNIEIARNMVYKAAWLKDQGRVFKKEAAYAKLFASEICMRACDQAVQIHGG
                     YGYMKEYQVERFFRDAKLLEIGEGTSEVQRMVIAKQIGC"
     gene            45613..47568
                     /locus_tag="A4U60_RS18515"
                     /old_locus_tag="A4U60_18355"
     CDS             45613..47568
                     /EC_number="6.2.1.1"
                     /NRPS_PKS="Domain: AMP-binding (93-526). E-value: 5.7e-86.
                     Score: 280.6. Matches aSDomain:
                     nrpspksdomains_A4U60_RS18515_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394143.1"
                     /locus_tag="A4U60_RS18515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18355"
                     /product="acetate--CoA ligase"
                     /protein_id="WP_113753839.1"
                     /sec_met_domain="AMP-binding (E-value: 3.4e-95, bitscore:
                     312.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDINGILQVVANSKLIFPNKEKVRSTSIGSIEAFQELLRQSQEDP
                     AAFWDSAARDLVWYEPWNETISGQLPDFRFFVDGISNPSVNLLDRHIVNGAGNRTALIW
                     EGENGDTKFYTYNMLLAEVNRFANVLRSFGVKKGDCVAVFLPNLAEAFIAVLACFRIGA
                     IYNTIFSGYSEKSLKDRLISFGPKVVVTADATERRGKAIRLKEKVDYVAPTIPSVEAVI
                     VVDRLGLEVQMKEGRDYWWHELTKTASIVCEPERIEANESGIVFYTSGTTGKPKGVVHS
                     GMAFVTQNYTYAKYHMDHHNDDVFWCTADIGWLTMHIWGITGALANGVTTVVYEGAVDY
                     PEKNRFYQIIEKYRVNKLFTAPTALRMLKSMGEKPLEQFDLSCLDVISLVGEPFDTETW
                     HWTYEVLGKKKVYINNTWGQTETAGSPIAGAAWLTPMKPGSSGTQFLGAVFDVVDEEGN
                     PVKTGQLGNLVIRKPFPMMCRTLWKEPERYYASYFSQVEGSYYASDLALVDEDGYLWVV
                     GRSDDAFNVAGHRLSTLEMESAVLECEGVFECAVIGIPDEIKGEVPLVFARLADGFEGT
                     KEIIERINNNIIQQIGKIASPKSIIITNMLPKTVSGKIMRRLLKEIVATGKVAGDITGL
                     EDPSTVVEIQKIVADK"
     aSDomain        45892..47190
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS18515_AMP-binding.1"
                     /evalue="5.70E-86"
                     /label="A4U60_RS18515_AMP-binding.1"
                     /locus_tag="A4U60_RS18515"
                     /protein_end="526"
                     /protein_start="93"
                     /score="280.6"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="NGAGNRTALIWEGENGDTKFYTYNMLLAEVNRFANVLRSFGVKKG
                     DCVAVFLPNLAEAFIAVLACFRIGAIYNTIFSGYSEKSLKDRLISFGPKVVVTADATER
                     RGKAIRLKEKVDYVAPTIPSVEAVIVVDRLGLEVQMKEGRDYWWHELTKTASIVCEPER
                     IEANESGIVFYTSGTTGKPKGVVHSGMAFVTQNYTYAKYHMDHHNDDVFWCTADIGWLT
                     MHIWGITGALANGVTTVVYEGAVDYPEKNRFYQIIEKYRVNKLFTAPTALRMLKSMGEK
                     PLEQFDLSCLDVISLVGEPFDTETWHWTYEVLGKKKVYINNTWGQTETAGSPIAGAAWL
                     TPMKPGSSGTQFLGAVFDVVDEEGNPVKTGQLGNLVIRKPFPMMCRTLWKEPERYYASY
                     FSQVEGSYYASDLALVDEDGYLWVVGRSDDAFNV"
     CDS_motif       46405..46455
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4U60_RS18515_0001"
                     /evalue="8.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="A4U60_RS18515"
                     /protein_end="281"
                     /protein_start="264"
                     /score="21.6"
                     /tool="antismash"
                     /translation="VFYTSGTTGKPKGVVHS"
     gene            47781..49142
                     /locus_tag="A4U60_RS18520"
                     /old_locus_tag="A4U60_18360"
     CDS             47781..49142
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394144.1"
                     /locus_tag="A4U60_RS18520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18360"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_113753840.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.6e-14,
                     bitscore: 47.4, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 9.9e-11, bitscore:
                     35.1, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKKVLIANRGEIAVRVIRTCKALGITTVAVHSEADADAPHVKMA
                     DDAYLIGGSRVEESYLNIDKILEVARLTKAEAIHPGYGLLSENAEFARRCEEEGLIFIG
                     PSPKVISKMGSKIESRKAMEEAGVPFVPGITYPLADAEEAVEAADRIGYPVMLKASAGG
                     GGIGMQVVHSGDEIRKAFAGNQKRATDFFGDGAMYVEKFVENPRHIEIQILADGFGNTV
                     YLWERECSIQRRHQKVVEEAPSSFLSETTRSKMGEAAVKAAKSIGYKNAGTIEFLVDEE
                     QNFYFLEMNTRLQVEHPVTEEITGLDLVEKQLKIAGDEALDFSQEEVKREGHAIEVRIY
                     AEDPKTFFPSPGKITKLELPNGPGIRHELGVHDQSSVTPFYDPMIAKLIVKGSDRDDAI
                     NRLQDALADYHIEGIKTNIPMLEEVIAHPAFRSGDTTTDFVGKYLKIKKANNMK"
     gene            49154..49366
                     /locus_tag="A4U60_RS18525"
                     /old_locus_tag="A4U60_18365"
     CDS             49154..49366
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013876843.1"
                     /locus_tag="A4U60_RS18525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18365"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_061804166.1"
                     /transl_table=11
                     /translation="MSEIVASMAGNVWKVLVKVGDQVEEGQDVVILESMKMEIPIAAEF
                     DGTVKEVKVNEGDFVNEGDTIVKVE"
     gene            49401..50324
                     /locus_tag="A4U60_RS18530"
                     /old_locus_tag="A4U60_18370"
     CDS             49401..50324
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394146.1"
                     /locus_tag="A4U60_RS18530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18370"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_113753841.1"
                     /sec_met_domain="HMGL-like (E-value: 3.5e-55, bitscore:
                     181.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKWPTNITIKEVGPRDGLQNEKGFISTEDKIALINQLSASGLKEI
                     EITSFVNSKWIPALSDASVVATGITRVPGITYTALVPNQQGLERAFEANIDEVAVFMSA
                     SETHNLKNINKSISDTFPILRDLVQKTLAAGKSSRGYVSTVFGCPYEGAVDIDMVIRVS
                     ETLFEMGIKELSLGDTIGVANPKQVQELLEVFLKKFPADKLAMHFHDTRGTALANVLVS
                     LEMGITTFDSSIGGLGGCPYAPGASGNVATDDLLYMLHGMGIHTGVDQEKLLSASQFIQ
                     KKIGRPLPSKSLQASISKYNSTCENT"
     gene            50341..51123
                     /locus_tag="A4U60_RS18535"
                     /old_locus_tag="A4U60_18375"
     CDS             50341..51123
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (8-252). E-value: 5.4e-74. Score:
                     240.5. Matches aSDomain:
                     nrpspksdomains_A4U60_RS18535_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422141.1"
                     /locus_tag="A4U60_RS18535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18375"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_113753842.1"
                     /transl_table=11
                     /translation="MDKTILVNRLENGIVMITLNRPEAANALSLQMLGELQEAVLLCKY
                     DRTIRCVVITGAGEKAFCAGADLKERADMEHVQVRKTLSLIQGNINDLEALPQPIIAAV
                     NGVAFGGGTELALACDIRIASETAKLGLTETSLGIIPGAGGTQRLPRLIGKGRAKELIF
                     TARRIDAAEALEIGLVEYTVPSNHLMEKALEIAGQIVRNGPIAVTQAKFAIDKGYDVDI
                     NTGLAIEQSAYEVTIPSKDRLEGLQAFKEKRTPIYGGE"
     aSDomain        50365..51096
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4U60_RS18535_ECH.1"
                     /evalue="5.40E-74"
                     /label="A4U60_RS18535_ECH.1"
                     /locus_tag="A4U60_RS18535"
                     /protein_end="252"
                     /protein_start="8"
                     /score="240.5"
                     /tool="antismash"
                     /translation="RLENGIVMITLNRPEAANALSLQMLGELQEAVLLCKYDRTIRCVV
                     ITGAGEKAFCAGADLKERADMEHVQVRKTLSLIQGNINDLEALPQPIIAAVNGVAFGGG
                     TELALACDIRIASETAKLGLTETSLGIIPGAGGTQRLPRLIGKGRAKELIFTARRIDAA
                     EALEIGLVEYTVPSNHLMEKALEIAGQIVRNGPIAVTQAKFAIDKGYDVDINTGLAIEQ
                     SAYEVTIPSKDRLEGLQAFKEK"
     gene            51154..52692
                     /locus_tag="A4U60_RS18540"
                     /old_locus_tag="A4U60_18380"
     CDS             51154..52692
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422140.1"
                     /locus_tag="A4U60_RS18540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18380"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_113753843.1"
                     /transl_table=11
                     /translation="MDMKPLQQILEERVEQIKKGGPSKYHEKNTEQGKLFVRDRLKQLF
                     DPGFELEDALFANYMAGELPADGVVTGMGKINGQVVCVMANDSTIKAGSWGSRTVEKII
                     RIQETAEKLRVPLIYLVDSAGARITDQVEMFPGRRGAGRIFYNQVKLSGKVPQICLLFG
                     PSAAGGAYIPAFCDIVIMVDKNASMYLGSPRMAEMVIGEKVTLEEMGGARMHCSVSGCG
                     DVLAKNEEEAITIARNYLSYFPANFLEKPPVHEAAAPKQMKRSLEELIPANQNSPFNMH
                     DLVNGIIDEGSFFEIKKLFATELITGLARMDGKPVGIIANQPRVKGGVLFHDTADKAAK
                     FINLCDAYHIPLLFLVDVPGFMIGTKVERAGIIRHGAKMISAMSEASVPKISVIVRKAY
                     GAGLYAMAGPAFEPDACLALPSASIAVMGPEAAVNAVYANKIASLPEEERAAFIAEKRE
                     EYKEDIDIYRLASEMVIDGVIPANSLRDELIKRFEVYSSKYLIFSERKHPVYPV"
     misc_feature    52775..52788
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.52"
                     /tool="antismash"
     misc_feature    complement(52776..52789)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 26.06"
                     /tool="antismash"
     misc_feature    complement(52970..52988)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.84"
                     /tool="antismash"
     misc_feature    53305..53323
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.97"
                     /tool="antismash"
     gene            53456..54154
                     /locus_tag="A4U60_RS18545"
                     /old_locus_tag="A4U60_18385"
     CDS             53456..54154
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394417.1"
                     /locus_tag="A4U60_RS18545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18385"
                     /product="copper homeostasis protein CutC"
                     /protein_id="WP_113753844.1"
                     /transl_table=11
                     /translation="MFIEFIATTLEDALLIEQSGANRIELVSALTEGGLTPSHSLIEAV
                     VNRVSIPVNVMVRPHSQSFCYSHDDFSIMKNDIRIIRSLGANGVVLGVLNEKHEVNQHI
                     LEELLRECNGIEVTFHRAIDCTISPVQAAKILAQYKEITTILTSGGNNEFSSRLQTIQK
                     MKTVCKHISILVGSGLNTSNILSVHSTVQTGHYHFGTAVRKNHSLIEGIHLEKAKEMVQ
                     ILKDEERKSV"
     gene            complement(54480..54944)
                     /locus_tag="A4U60_RS18550"
                     /old_locus_tag="A4U60_18390"
     CDS             complement(54480..54944)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008343886.1"
                     /locus_tag="A4U60_RS18550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18390"
                     /product="DMT family transporter"
                     /protein_id="WP_113753845.1"
                     /transl_table=11
                     /translation="MGTIMVLFTLLGGIMLSAQSSVNGPFSRKAGTIEATLLTFITGSM
                     FLAILILFFGEGNVLKILEAPKWQLSAAFLGTLYGLFVITAVPKIGVIATNIAGIVGQL
                     VISILIDHFGWFNSLIIPFDLKRFFALLFMLVALYFIYTGNKRSSEETYA"
     gene            complement(<54959..55343)
                     /locus_tag="A4U60_RS18555"
                     /old_locus_tag="A4U60_18395"
                     /pseudo=""
     CDS             complement(<54959..55343)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016764762.1"
                     /locus_tag="A4U60_RS18555"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="A4U60_18395"
                     /product="DMT family transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLSYLFALLAGAALSFEGGIYAELGKTIGKLETSFYNFFMGSIIV
                     GLIWLFAGKGKLSYTVEAPKWSLMGGFFRRRLSNFHRDQCSLCWGWYYDGCCHNRSISH
                     EYGD"
     gene            complement(55700..56620)
                     /locus_tag="A4U60_RS18560"
                     /old_locus_tag="A4U60_18400"
     CDS             complement(55700..56620)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019390820.1"
                     /locus_tag="A4U60_RS18560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18400"
                     /product="arginase family protein"
                     /protein_id="WP_113753846.1"
                     /transl_table=11
                     /translation="MKEHKEAAKSKTLRLLMPQWQGGNNPPYVLGAHLLNWLAPKTNGP
                     FEEVPIDLDSSLEIEQGIVAKSVLLNQARSAKSVIQKHSPDSIIVLGGDCGVELAPFAY
                     LNEKYDGDTALLWVDLHPDVSIPEEFPNHHAHVLANLLGIGDKEFVAEVPRSFKPEQVL
                     FVGLNDMMEALNSKPLQDIKMNIATPDDIKEDSSKVLQWLDSRKPSKVIVHFDLDVLDL
                     REFRSLLVANPATYEEMKDRVPTSSSMETIIRVLQDVAKAHDVVGLGITEHFPWDAYNL
                     QNMLQRLPLLGDINKKDKAPYNWIF"
     gene            complement(56702..57538)
                     /locus_tag="A4U60_RS18565"
                     /old_locus_tag="A4U60_18405"
     CDS             complement(56702..57538)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014114551.1"
                     /locus_tag="A4U60_RS18565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18405"
                     /product="MerR family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_113753847.1"
                     /transl_table=11
                     /translation="MKQYFSIGETARLNNISIQTLRYYDKIGIFKPHYTDQDNGYRYYH
                     IKQFFYLDIIKYLKYIRTPLEEIRRIISGNPEHMQTFLEEQESVIEDEMDNLERARRLL
                     HRRKNQLKEQLEICNREKGIVYFRYMEEQTILKVATPQVNPHDQSDLYFRKLVDVLEER
                     GDMVDNYYGFIYDLKPYKDSRDIYCNNIYTTICKGEKVDIEGKNIQLDTIPSGEYVCIS
                     FDWSTKHYDSYYQELYHYIESNSIQTDGKVYQISLPTNYSSLREEQFLTELRVLKK"
     gene            57899..58846
                     /locus_tag="A4U60_RS18570"
                     /old_locus_tag="A4U60_18410"
     CDS             57899..58846
                     /GO_function="GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007430567.1"
                     /locus_tag="A4U60_RS18570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18410"
                     /product="nitronate monooxygenase"
                     /protein_id="WP_113753848.1"
                     /transl_table=11
                     /translation="MKNNNRICDILGIQYPIVQAAMSWITDAKMVAAVSNAGGMGVLGP
                     NAGSNFEGSKKISTEERLRNELRKTKSLTDKPFAVNIFSPEEGTDDTYTQTVLNISLEE
                     GIQTFLSVGFVNKKLFRQIKDHNATLIHRELTPTPEAAKMAESEGADIIIATGYDEGGW
                     IPQNQIGTFSIVPTIVDAVDIPVMATGGINDIRGVRAVFALGAEGVYVGTRFIVSEECP
                     ASDITKQDIIRSKAKDLVFVSSLQRSTPHKLARELESMYKNGMSPDEEMSLRPGMLEGK
                     LDEGIVSVNTAIDVITEVKSCEDIVKELMADFIK"
     gene            59115..59480
                     /locus_tag="A4U60_RS18575"
                     /old_locus_tag="A4U60_18415"
     CDS             59115..59480
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012927.4"
                     /locus_tag="A4U60_RS18575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_18415"
                     /product="hypothetical protein"
                     /protein_id="WP_061804174.1"
                     /transl_table=11
                     /translation="MKELYKPLFEPCTFPCGIEIDNRIIMVPMATKSSFENGMVTLDEL
                     AYYKRRTKGLGMVITSATRIEKYGSQPGSISIATDKHIQSLSKLANTIKSNGTKAILQI
                     FHVGRMQTSIVEKRYFS"
     misc_feature    59876..59893
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.1"
                     /tool="antismash"
ORIGIN
        1 taaaattaag gattttgaag tttaaaactt gtaatctaat aagtacttca acttagaaat
       61 agtgatggta acattgaaaa tgaaaacatt agagttaatc ttaatgagct tctttatcta
      121 cgctgctcta caaataacaa aggttataga ctctacaggt ttctaatttg ttgcgttaga
      181 gcttttcata actaatagta ttttttaaag gaaaagagaa ataaacaaac atatttatta
      241 cagaatatca agcctcacta ttatatcggg gggcttggta ttcttttaga taactatttt
      301 tgtgttgcaa gttttcttat gaagatgaat aatggttttt atttaattct ttctttgtta
      361 ctagaattta ttttatgtta actaaaaaag cttcttcgtt tcctatgatg tgattatttt
      421 ttgtaatatt ttgatagttt ttgtagaaag ggttttcatt ttgtatgata ttgttcataa
      481 tgtttttgag tgttccttgt atatgggtga ggacatgtac aagggaccat ttttaatggg
      541 ggaggaatag ttcatgtggg tgattacggt tcattcaagg aaaaacacaa aaatgtttga
      601 atttaacaca gaaaaggaag caagagaagc ttttaaagac atcgaaggaa gtaagattct
      661 tactgaggtt atctatttta atagtcctta tcttgcttca tctacggttt aagtgagatc
      721 tttttttatg tgagattgtc cgtaaagaac agggtaaacg taacaaagta gttatatgaa
      781 aaaagacggt ttatgttaac taatttagag cgaattactt ttaataagag aatcctttgc
      841 taattataag caaaggattc tcttatttat acgaataggg gaatacataa gtagtttgtt
      901 caaatttata gattcatata catatctatt ctaaaaagtt ctcctgagtg gtttatgact
      961 gataatcaag attagaggaa ctaagatatt tattgcttaa aaaggtttta tccagaaaat
     1021 catgttttat aaattgtgaa ttcatattga tttactttta ttaatcccca taattatatc
     1081 ttctgtatta gctaattaat cgcttagtat ataaatatat acatttttaa ctgtgctaaa
     1141 gttataggag gattcatact attgacgcta gaataacttt actgaaatac actataaata
     1201 tcgggattaa taaaggagag ttcatatgcc aaaaattgaa gaaaatcagt tgtttacggt
     1261 aattattgaa tgggaagtta atccaaaata tcagcaagac ttaattaatg gtcttacaaa
     1321 tcaaattgaa acatatttta agaattacga tgggtttatt tcatcaagtt tccatgctag
     1381 tgaagatggt aaacgagtta ttaattatgc ccaatggata tcggaagaag cttggtctaa
     1441 ttcgtttcaa gcttcagggc gtgatgaagt ccaaactact aatgatgaaa ttattagtcg
     1501 ctgtgaggct aaaacattaa aacttaacaa gtatcgtgtt gcgagagtaa tagaaaatat
     1561 atgaagtaat gattactcca ttagaataac tagcgagaat gggttttacg gtaactaatt
     1621 aatgttaaag ttcttgtggt aaaaaacctt tgcttagcat tagcaaaggt tttttgaata
     1681 tataattata ggggaatacg ttaatagttt gtccagttgc ttagattgct atacatatat
     1741 agaaccccta ctcattatag aagagggatc ttttcggtga actttcatag ctaatgagta
     1801 tcatactcat tagcacttag ttatcttata cttattttat gataattctt ttatatacca
     1861 agcatcgcag gcattatgct ctgtttcatc tagtggtgtt tcaagttgtc ggaaatcgaa
     1921 tttaacataa aggaaattag ctgcttggag ttccttaaat gtctctaggt aacagcatgt
     1981 atagtgttcc tttgcgaagt cgagtgctac tttcattaat tctttcgaca gacctttccc
     2041 ttgagcttcg ggtgaaatat agagcttttg cagctcgcag acctcttttt tttgtccaaa
     2101 tggtgcaatc cccacaccgc ctatcacttc atcttgagca ttcactgcaa cccaatattt
     2161 tgcattttgt tgctgctgat aatactgtga taaactgctc agctggggat caaaataagc
     2221 tgttcccggg atattcaact caaatgattc caaagagtgt ttaataattt gctccatcct
     2281 ttgattatct ttttctttca tttcacgaat ctgcatggtt tcatcctcac attcaattat
     2341 tttaatggtt agattctatt tgtttctaac aaatggatgt taatcatatt cttctcataa
     2401 cccatggaat aatagcaata gatcagccat ttgagtagtt atccatgtat caattagcta
     2461 acctgaacca ataatggaac ttaatccaac cattgttgaa gcaaaagttc ccatcctttc
     2521 acttaaaaga tagatagctc tatcacctgt ctccgctgtt ataatttaag acattcagtt
     2581 ataaaaagtc tcttttatat ctcccatcta atctctccac catttgatat ttgaggatgg
     2641 ttgtttatga taaaattata atgagaaaaa agtattaaag actactttgt gaactttagt
     2701 atatgatata tccctatagc aaacaatggt tatggaggat tcatggataa tctgattaaa
     2761 ataaaaggaa aagcccaaac acattgagaa acaatgcatt tgggctcttt tactccctta
     2821 catgtaaatt agatttgcat atcatataca tgcttttttg aaggatgtat ttatcgtgac
     2881 atcgttatag gaagggtttt gtactatctt gatagttatt acactatcca attagtctgc
     2941 acatctttta tgctgagtac atattttgtt ggggaatttt atcaatcaca atccagcgat
     3001 tataaagatc aattaaaaat ccaattccga acataaataa gaaggtgctt atgcccaaac
     3061 cagttatatg gtgttgaaaa agaatgataa gaatgctaat agataatggt atcgacgtac
     3121 aaatcattgt tcctactgta tagttgttca ttcgctttcc aaatgctttt aacaaatagt
     3181 cagacggtaa atatatggag cctgattgaa aataaataca tacagcgact gccataaggt
     3241 taagccctat taatgaatat aaacaacgga tccataaatt ctccggtaca tacataatgt
     3301 gatgtaagtg cacaaacaaa tcaataaaca ttccaaaaac gaaagtgaga gccatacttt
     3361 tgataatcat agccagggtg aattttgttt ttattaaata actaagtata aacgaaaaga
     3421 aatttaaaat aataatgcaa gcaccagtgg aaagcggtaa tatgaatgca aggttttgcc
     3481 cagcagctgc ccaaggggaa cttcctaggt tagaaatgat cataaagcta tttcctaaag
     3541 cattcaacat aattgaacaa acaaaccata ataagtttac aggaatattc ttcatcataa
     3601 cctccaattt ttaagatact ttttgtctat tatagaaaag gttaccctta cgctgcaaag
     3661 gacaattgaa gtaattatac ttttcataac gaattcaatc atttgacact atgtaaaaaa
     3721 cttggcgctt tttctacaat acgccctatc agtataggtt ctagaatttt atacgatttt
     3781 tcgtaaaaag gaaaccccta atcgataaaa accactgtta agaatccttt tagaaagaag
     3841 gcttcttttc acatgatttc cgatagcgaa cattatataa agcagttact tatattgtaa
     3901 gactttactc tgtggtaaaa tttagttaga aagaggtgtt gtatatgcaa aaacaacaaa
     3961 gtattactat acttttatta atgttagggt tagcatctat ttctttaggc atggctttaa
     4021 aaaatgtgtt tgagtattct cctatctttg gctggtttct aggaacattt atatttatag
     4081 ttaattcttt ttacacagga aagaatttga gaaataaaga tgctaccaac cttaagtaat
     4141 ccatagttaa tgttttaaga cgcttgaatc atttgattca agcgtctttt tagccgatag
     4201 tttatttaat gtcaatagga aggggcatca caatatggaa cttcattaca gaaggatttg
     4261 catcaatata tcgttttaga ttacaaaaac ggtctaacaa attcatctat cgtttgtcta
     4321 cgataaagat atatggagaa taggccgtag gggagctctg caaatcattt ctaattgtaa
     4381 tgaatgcacc agtctcaaaa gagattaggt tgtttaggtt tagtatttta gaacagatat
     4441 ataggttatg tatcagctaa aagagaatag agttaaaggt tattgaaatc gaccaaaatc
     4501 aactcaacaa cttatgactt ttcctaaaag tcttgctgtt tcctctttaa aaagcccttc
     4561 atcatcctaa gtttttaagt ttataaaaga tttatttgga atatatcttt aaatattcag
     4621 agttttcata tagaataact ctaaatgaca gaaagtctca catagtattt ataaagaggt
     4681 agaaaggaca gcagagtatt atgatagaaa agaaacttga aaagaatgta agtaatcagg
     4741 taagtatagg ggtaaacata tatttaagaa aaatgaaggg agaaggtaga ggaaaaagta
     4801 aaatcaacta tagggattct attgtttcag ctacaggtgt acttatcgct attattatca
     4861 ttagttttat gactcttcat ttaggttacc ccatggcaat agctccttta ggagccagtt
     4921 gtatactcat atttgaggct cataaaggtg catggtctca accacgaaat gtgataggag
     4981 gtcacttact ttctactact tctgccctta ttatttggag tttactaggt aaaagtttgt
     5041 tctctatagg gatagtatta gctattgtgt taatcctaat ggctcttacc aacactcttc
     5101 atcctcctgc agcagctagc gcacttgttg tagtgaacag tcaaacagga tggggatttc
     5161 tagttcctat atccctagga gttttactat taatttttat ttcaattctt tacaataatc
     5221 tattttccaa acgacaatat cctcaacact ggttatgaaa cgctaagtag gaagtaggat
     5281 aatagaataa gagattagct ttcaatacag aggggcaaag ccaaaaggat aggagaaacc
     5341 atatcctcca ttttcccgac tcatagatga tctttgatgg aaattatgat tcaataaaag
     5401 cctttttcac ataattaagg gatggatata ataacatagt gataaattca ttcatctaaa
     5461 agaaaattcc ccacatcgta gatagtgggg gattcttttg ggttactaat gattagaatc
     5521 agctgactaa gggcattttt atgatagagg taaaaaatat tactttattc agagtacgta
     5581 gaatttgttc gaataaattg tacatataga taggcttggg ctatctaact tatagagaag
     5641 cttacctttc tgtttttcct tgaatattaa tcttggcatc tataagaaac aaacctgtaa
     5701 ttgatcaacc tatatcttcg tttatttcat ttgaatgggt aataattaac attatggtga
     5761 ctgagagtga ataggatata tattttaaaa atataacatt taaataattc ctttactttg
     5821 taatcgcttt catttataat gagagtaggt gggatggcat gagtggctgt cacagtatct
     5881 agcgtaggtg gggctgatac aagggaacag ggcatataag gaatgtcctt ttttatttga
     5941 ataaagttga tttatttcgt tattcaaata aagatggggt gctattaata tcgaactact
     6001 gtttaaataa ttaaaattac tttttacata gaaataacgc ccaattaact gggcgttatt
     6061 tttatgtaaa gagattcatg taaaagatct tttttgtgtc gctgtctaga atccctttta
     6121 tgggaactac aaatgtgtag agtatgtata aaataacaat agatcccttt atttaacaaa
     6181 ggaatctatt gttaggatta aaagaagagt aggtatgttc atttaacata aaatttgtaa
     6241 atcaatcttt gtataactga taaattcttt ttaatttttg ttccaactgt tcaaaatgga
     6301 cgaaacgagc ttctcttaca aattcagttc cttcaataaa caaaagaagt acgagaacag
     6361 taaaaactga aaatctgcca gcaacctctt ctacattatt agcgtttata tgagctaatt
     6421 tgatacttgg aaactgctct aacaatactc ttagttgtgg cagaacagcg tgacatacta
     6481 cgcattctgg ttttgagata tataagaaac ttaacttgtg attgtttata aaattctcta
     6541 ttgaatccaa tgaaattaat tctgtcactt ctttcatcca actcctcctt tggattagaa
     6601 tgtatctgac ttgaaatata atagacccac cttgttcatg tctataaatc tgctttatat
     6661 tttataaaag ttgaacatta acgacttaac aagtttccta ccaaacagct agtatattga
     6721 ctaacttaaa attcaccgtt atttgagatt tatccttttc acttcctgga atggacgtta
     6781 tacagtacat atcggtattt tttttatttt cagcatattt ttaaaaattc tatcaatata
     6841 gagtttctat tactatatag attatttcta taattcacac cttgaaacta aaactataat
     6901 aaagaaaata gtttcattta ttggaaatgc aaggttcaaa ataatataaa agtggtgaat
     6961 atagtgaaga aagtagtagg aattatgggt ggaatgggtc cattagcaac ggttgattta
     7021 atgcaaaaaa taatctcgtt tacccctgct gagaaagacc aagatcatct tcaccttata
     7081 acggacaatt tccctcaaat accagatcga acaacagcta ttttaggaaa aggaacagat
     7141 cctactcctt ttatgataga gtctgcacac cgtttagagt ctgcaggagc agactttctt
     7201 gtagtagcat gtaacacagc tcatttcttt gttaaatcag tagaaaatgc tgttagtata
     7261 cctattttac atatgccatt agagacggct aagtttttaa agaaacatca ttttaaaaaa
     7321 gtaggattat tagctactga tggaaccatc aatacaaaac tgtaccaaca tagttgccat
     7381 cattataaaa tagaagttat tgaaccaaat atacaaatgc aaaaggaagt aatgaaaggt
     7441 atctatgcaa ttaaaggagg gaagttagaa cagggtagtt cttatctttc aaaaattgct
     7501 agaagcttaa ttgaagaagg tgcagaagca attatagcag gatgcacgga gattccttta
     7561 gttcttaaat catcttcatt ttcagcaatt attgacccaa cagagatttt agctagagct
     7621 gtaatcaaaa atgccaatga tctgataaag tgttaatgga ggttaatatt aagaatagac
     7681 attcattata ataaaatata tccatctata tatataaata aggagcaatt agaaaatgaa
     7741 cattgaaaac attgaagctt tcctatacgt ttgtcaacta ggtagtttca acaaagcagc
     7801 agaagctctt tatttaactc agccttctgt tacagcacgt atccagtcat tagaacggga
     7861 gatgaatata aaacttttta atagagccgg gaataaaaca tcattaactg aaaaagggga
     7921 gtatttcttg cctcatgctc agaaaattct tcaatcttat caagaagcaa catatggatt
     7981 gcaacaagtc tttattcctt atgagttagt gattgggagt gctttatcga tttcaaacaa
     8041 tgtattgcca aatatcctgc cagctttcaa atccgaattt aaggatgtta gaataaaaat
     8101 cttaacaggg cattctaaag atattctacg taaggtcatt aacaaagaag tcgacttcgg
     8161 aattataaga acggaggctc attctcaaat tgaatctatt cgtctttata atgaccctat
     8221 aagccttttt gttccaccaa atcatccatt tttaaaaaaa gaaaaagtaa caatagaaga
     8281 tgtaggagag caccccctta tcttatttga ttacggctct atggattggc ttttcattca
     8341 tagattattc ttaagcaaag gaataaatcc gaatatatat ttagaagtgg ataatatgga
     8401 aactgctaaa aatctagtac tgcaaggatt aggtattagt ttcttgcctg cacattgtgt
     8461 gcaaaaagag atagaacata ataaattatt ccgagtagaa atggacccag atataaagac
     8521 taatattagt attgatttta tatatctaaa aggaaaatca gagtctgtat ttatggattt
     8581 ttttaagcat aaaatgttcg aataacaata aactggttga ctatcaaccg gtttattgtt
     8641 attttacact cataaagaaa gcctttgctc agaatgagca aaggtcttac ataactgatc
     8701 cttttaatat acttactctt taatgaacga gcttctgccg acttacatta agagttttgg
     8761 ggtaggagct ttatttcatt tatcagaaaa aattaagaaa ctcaggtttt attttcacat
     8821 agcgaattat ttcaatgtta taattatgtg ataaacttag tgaggtgaag aatatgaaac
     8881 ttactataga tcaaacaaag ggagacaaga aagtgccagt atattcaaga acaaacccat
     8941 ttcaagcaaa ggtgctcaaa aatattaatt taaatcatga gggctctaat aaagaaacaa
     9001 gacatattga attctcttta aaagattcag gattttctta cgttccaggt gatgctttag
     9061 gtatcgtgcc tgaaaatgat caagaattag tagctgaact tctgacagaa atgcaatggg
     9121 atggagaaca agttgtaacg attaataaga aaggcgatac acttccactg aaggaagcat
     9181 taacaactta tttcgaaatt acgttactaa caaagaagat tttacaacaa gcagcacagt
     9241 ttacagaaag tgaagagcta aaagcgcttt tagatgctga agatgtaagt aaagtaaagg
     9301 aatatattta tggacgtgat ttacttgata tgttacgtga ctttggtccg tggaaggctt
     9361 ctgcccaaga aatcgtatct cttttaagaa aaattccacc acgcctttat tcgattgcaa
     9421 gcagtttagc tgcaaatccg gatgaagtac atttaacaat tggtgttgta cgttatacat
     9481 cttacgacag ggaccgaaaa ggagtttgtt cggttcaatg tgcagaacgt gcagaagcag
     9541 gggatacact tccaatcttc attcaaccaa ataaacattt tcatctgccg gaatcagaag
     9601 aaacagatat cattatggtt ggtccaggaa ctgggatcgc gccattccgt tcatttattg
     9661 aggaacgttc agtaaataaa ggtagtggga aatcgtggtt attctttggt gatcagtatt
     9721 cagcaacaga tttcctttat caagacgagt tagagaagta tcaaaaagag ggtgtactta
     9781 caaagttaga cacggcgttc tctcgtgata cagaacaaaa ggtatatgta cagcataaaa
     9841 tgcttgaaaa tagcaaggaa ttgtatgaat ggctacaagc tggagcttat ttctatgttt
     9901 gtggagataa ggagtacatg gcaaaagacg ttcacgaagc attgatttcc attattgaaa
     9961 aagaaggaaa catgagtcgt gaagaagccg aagaacagct agcagctatg aaaaaagaaa
    10021 aacgttatca gcgtgatgtg tattaagata ggttagataa aaagaacacc cccatttcac
    10081 cttaggtatg tgtgatgggg gtgttctttt tatctcattt tattaattag ctctatgtat
    10141 tgtgaatctc catatcctat tgtcgggaaa agattaaata acctattcat taattctgat
    10201 gttggtaaat ctttattttt ggaaatatac tttactactg cattattttc tttcagcata
    10261 tctaaatata tatctattgc ctgatacatg actggaagta gttcatttga tggtttttta
    10321 tgatttacca atacttcgtt gtatacagca taatagttac ctaattcaag ttcagtttga
    10381 cttactttaa attcatcttc tctaaagcta tttaagaaca ctttaccatc atacccggat
    10441 tgtttaagat aggaaagtaa tgtaagtagg ttcatttgac aaaacatgtc ttcaccaaac
    10501 cataaaacaa tacatttata ctctttatta aaaagattgt ctaatggatt gataaccttt
    10561 ttaatatact tttccactgg ttcatgatgt cccgatgctc gtgtttttat aaactcttca
    10621 ttaaaaacat gtttagtagt cgcgtttaca cacatcgctt cattaaatgg aacgtaatcc
    10681 gcatctccca ttagtttttt atctttaaac tcttcataca taacctgacc attcaatatg
    10741 ttgagtacat atttgtcgaa aaactcactc ttctcatttt gtaactgttc aacctccatt
    10801 tttctagaaa tattcattct ccaccattcc ttgtctttat ttatagtgag tttaacaaat
    10861 gattgaacag gcatcttgtt aacttgaaat tctcttgggt ttacaccaaa aacggtttta
    10921 aaagccctac tatatgcttc ttgtgaagaa taatcgtaat caaaggcaat atcaatgatc
    10981 tttctatcct ttgccaaatc taccgtagat aaatacaatc ttctaagaag aatataacgc
    11041 ctaatactta tacctgtgac ttgatggaac ttaaaagaac aataataagg agaatacccg
    11101 atataatgag ataattcatc tagcgaaaat tcatttttta atttgtcctc aatccaatca
    11161 atcataagct gtatatgttc attcatttat ctcactcctc aagaaaatta taagaggtat
    11221 caagttcttc cttttgatat ttgttgtgat ttataaaatt aataatggta aaaagattga
    11281 aaagcaaagt ttttctcagg attttgttct tccatcaact tcttaacaaa ttattttact
    11341 gttctaaatc acctaaaggt atctggttgg tcaatgaaag agtcttctta cccttcatga
    11401 aatcctttca ttatttaatt atttcacatt acaaaccgtc cgtaaaagta ttgaaaatag
    11461 gaaagtaggg gagaataaat gattagataa gatgtacaag cgtacaggtt aaatcgttgg
    11521 gtaaaggggg gagttcctag acagtggaga aagccaaaat tagcgttatt caactatttg
    11581 ccttgatgtt tatatttgag atggggactg cagtggtcac aagctatgga ataaatgcga
    11641 aaaaagatgt ctggctggcc attcttttag gaatgtttgt aggaatagtc ttttttttcg
    11701 tttattactt tttatttcga caatatccca acttacctct tactgggtat actagaaaaa
    11761 tatttggtaa atacctgggg tggattattg gcttgttata cgttctctac tttttgtata
    11821 gtgctgctga taatatacgt agtttcgggg atttgctgct ttcatcgata ttaccgaaca
    11881 ccccgttact agccatcatt atcttattcg ttcttaccgt gagttatgta ctttctctag
    11941 ggattgaagt agtagggaga acagcggaag tatttattgt catattgatc ttattgggta
    12001 tatcaggaaa ttttctcgtt cttgtttcag gcaatgttga cttacataat atccagccgt
    12061 ttctggaaaa cggctggaca tccatcttaa cgacggcctt tctagagact agcaattttc
    12121 cttttaatca aatggttgtc tttatgatgc tgcttcctta tttaaatcgt cctagattag
    12181 tgaaaaaagt atggttgtct gccttgattt taggtggtct tatcttatgt tggacagcaa
    12241 gtttaaatat cgctgttctt ggtgttgaag aagtaaagaa atctactttt cctttgttat
    12301 taaccgttgg aaagatcaac ctttttgaat ttatccaacg agtagatgtt attgttgtgt
    12361 ttactttgtt gattacggta tttttcaagg catccatctt tttttatggt accttaatcg
    12421 gaatcgtaga tttgttcaag ttaaaaaatc atcaacagat tatcttgcca attgctttta
    12481 ttcttatctt tttgtcaatg actatggcct ctagttattc agaacacata gaggaaggta
    12541 cctatgtcgc tcgttatatc actatttatt tccatgttat tattccattg ctaatgctgc
    12601 ttgtcaccat gattcgtaac cgtttcaaga agaaagggag attgaaatca aatataacat
    12661 aataacctct aggtatattt caaagccatc gtgtttaaac aaatgcgaag gctttttgat
    12721 tgtcaggaac gaatgacaaa aaggattcca attggcatcc tttttttctt ctcatgggat
    12781 agattatatg aactgaagat ggctgtttta ggtattaaaa atggggagtt aaatagctaa
    12841 ttcccttttg tcttagaaaa gagggccgtg ataagaaaga tgatgccatt cacaaaaaga
    12901 agaatgccat aagcaaaccc tgctgcacca gcaccaaaag gattgctagt ataatacaca
    12961 ataataagca tacttatagt agtggctata ggagcccata gtaaggatac aactacacct
    13021 gagattatcc atctttttcg gttcctcaaa gaaaccttga tcacaatgaa atttactatc
    13081 atccatccta cgattaggct tgttatagat aaaaaatcaa aaatgtttca ttcctccttt
    13141 cttataacaa ataatagtga ttctcctttc ataatgaata ttagaaagaa aaattttata
    13201 taagttagac agatagtgat tgaaaaaagt tcataaagtt agagaattat aaaaataacc
    13261 ctataaagtc ctagtagagg tagtatagta aatagtacaa gtaaaagtta gctggatctg
    13321 tgtattataa aaataaaatt cattgatatt ctgaaatcat ccaattctta attattaaag
    13381 agaatagtga aatgatatat gaaagaaaaa gggagagcgt atgaaattta attatgattt
    13441 aagtggtcat ggttgggcca atgggtttat tgaaatgaac tctaaaagat ttgagtttcg
    13501 tccaagttat ttaacagatg cttttggaga tttattacgc agtctcgttt ccttactaac
    13561 acattatgag actttacgtt gaattactat ctaaaagaaa ggggagctaa atatgaagct
    13621 tgaaactgat agactgctgt tacaggctct tgaccttaat ttaattgagg ctacagctca
    13681 gcgtgataca caggcaatcg aagctatggg atacaaaacc aacggtgaat ggccagatcc
    13741 tgattttttt gaagctttac cctattttcg ggaacttcta attaaaaaca aaggaactaa
    13801 aggatttgat tcctggatta ttgtggagaa agagaccaaa gaaataattg gcggtattgg
    13861 ttttttaggt gatcctgatc cggacggtat gattgaaata ggctttgcta ctaatgaaag
    13921 ccaacgacgc aaaggttatt gttttgaagc tgcccacaaa ttattaaact gggccttgaa
    13981 tcagaaggaa gtcaaatgta tcactgctag atgccaactt gacaacatca attctaaaaa
    14041 tgttttagta aagttaggat tccaagttaa tcatacagat acagaattaa tttattggaa
    14101 tctacataaa taagaaaaaa agccatggag tcctttatta ataaggagac cgtggcttac
    14161 taaatttctt gaagatacat tatgttgagt ttaggtgtaa agatttgaaa ccaggactag
    14221 ttataatcta atcctgtttt caagttagct ttgagctgtt gtatggtagc tattttttaa
    14281 taggcgtttg ttaatcattt cgacaaaaca tttacaaata cctatgtcac agtaataaga
    14341 gaaataaacc tttctaatct aaacttaaat caattagttt ctcaccaata cctttgacat
    14401 attttatgta aactaagaat gcatatgata tatttagatt cacttgttta accactactt
    14461 ttaatctttt tataaacttt taaatcttca ataataaaat aattagggaa tttggtatgt
    14521 ttatttggat ttcctggcca tgtacctcca actgccaaat ttaaaataaa aaacattggt
    14581 tcttgtggaa taccttgttt agaagtgaaa atatgtttac catcaacata ccaatgaatg
    14641 gagttcttag tccatataat ggtgtactta tgaaaagtgg ctacattatc aattttaaat
    14701 gtagcataag accgatactt tgttttttct tcccagtggt taacataata cactttatat
    14761 ggattacttc ctatagcttc taaaatatcg atttccggca attcatctcc acttgatgga
    14821 agcatccaaa aagcaggaaa taatccttta ccttctggga ttttcgctat gatttcaatt
    14881 ttcccatatc taacttcgaa ttttcctttt gttgtaattc tggatgaggt gtattgttga
    14941 ccatggtgct ttttttgttt tgctattata taaagctttc catctctata cgatgcattt
    15001 tcttgtagat aaaattgcaa ttcatcgata tttcccttgc gttgaagttt agtccatttt
    15061 gatgaatcaa acatttgaaa atcttcatgc caaacgattt cccatgattt atgagtttct
    15121 tttttatctt cacctgtttt ctttttaatt ggttgaacat gattattgtc tttctgttgt
    15181 aacgttatag gtaaacttat agtacaacac atgattacac cgataataag gatgaaaata
    15241 aatagtttca acactgtact ccctttagca ttttcgtttt atatatcatt ttcactctca
    15301 attaatatat gaagaggcaa tttaatctta tgcgtgttga ggggtaataa agatgtctaa
    15361 aatcgacagt taggtgattt cattaagaga tcaagttgtt gaacttttgg gtggtaatat
    15421 ttacagggag gtgctttata ctgaactaaa tcatgctttt gaaaatttat atcaagcaaa
    15481 ttctaaaatt tgagaaaatc gatttctcct gtattgagaa atcggttttt tattattcat
    15541 aaaaactgcc ttaaatgctt agacttagca agagtaaagc tgcccaaata aatgatatga
    15601 ataaaagtgt ttgacacatc gcactacttc gtaatactat atagtggtac taagtaatgc
    15661 taagtagctt atgaggagga catatgaaag atttaacgga aatgcttaag ggagttcttg
    15721 aaggtgtggt gctccaaaaa attcaaaaag gagaaaccta tggttatgaa attactaagt
    15781 atctaaatga gttaggtttt gatgatattg tagaaggaac agtctatacc attcttattc
    15841 gaatagagaa aaaagggctc gtggaaattg agaagaaaaa atctgagctt ggccctgcga
    15901 ggaaattcta tacactgaat gccaaaggag aacaagaatt aaacgatttc tggataagat
    15961 ggtcattttt ggctaaaaaa atgaatggaa taaaggagca aagagatgtt taaaaagatg
    16021 attcaagaaa aacgagaata tcgtgcatat aaaaaaagag tgaatgaatt acctgaagaa
    16081 tacaaaaagg caatgaaagc aattgaaaat tatatgtgga gctttgctaa gggatcaggt
    16141 atgtttgagg ttttaaccaa tattttagag atgtttgaga gcagtgccag tgatggttta
    16201 agtatacgag aagtagtagg aaatgatatt gcagaatttg ccgactcatt cctagctgag
    16261 tttcctgaag aaacatggat tgacaaacta agaaataaat taagaaattc tattaaataa
    16321 aggagcgagc catgaactca actgttcttg aaatcaaaaa tgtaaaaaag agctttaaag
    16381 gaaatgaggt cttaaaagat gtcaatatca ctttgaagca aggttttgtt tatgccttat
    16441 taggggcgaa cggggctggg aaaagtaccc tattaaaaat tgttactggg ttacttaata
    16501 gtgatgatgg aaaggtaaca attcaagata ttaatattgc tgacaatcct gtgacagcac
    16561 aaaaactttt tagttttagt tctcagaatt ccaccgttga cggtgtacta actggatatg
    16621 aaaatcttca tttgattgcg aaattgcgac atgaacgtaa tccaagaaaa gttgccgaaa
    16681 gtttgttaga aaagtttgat ctgacggaag ccaaagataa agctgtttca aattactcag
    16741 gaggaatgcg acggcgtctt gacttagcta tgagtttagt tgggaatcca gaaatcattt
    16801 ttctagacga acctaccact ggattggacc ctaaaagtag gcaggatctt tgggatacga
    16861 ttaaagaaat gaagttgcaa gggaaaacaa tctttttaac gacccaatat ttagaggaag
    16921 cagattattt agctgatcag ataggctttt tacgtgaagg aaaaattgtt gccagtggaa
    16981 cccctgatga aatgaaacgt attgctggag tagataaatt acttcttgta tttaatcgta
    17041 atgaagacac cgatatagct ttaaaactct tagaatcata ttcctctgaa aaaaaagaca
    17101 attgtgagat ttctattgat ttaacagagg acatcacaac gactttaaac gtgttgaatg
    17161 ccctaacaac tgaaaatatt gagctcaaga cttttaaaat gattacccca acccttgatg
    17221 atgtatttat gacacttacg agaggaagaa aataatgaaa ataagacaaa atgcgggtga
    17281 tacactagca cttgccaata gaattattaa acacaatttg cgaagtatcg atacgcttat
    17341 tactgttatt gctatgcctg ttatgatgtt attaggtatg gtttatatat ttggaggagc
    17401 cattcaaatt ccaggggtgt ctcaagagga ttatataaat tatgtgcttc caggaatctt
    17461 actaatgacg attgccactg gttcagctta tacctcattg cgaataaact tagacaaaac
    17521 ttcagggatg tttgacagat ttaagtcaat gcctatatca aaatcatccg tactgggcgg
    17581 tcatgtttta gcgtcagttg tctttatgtt agtttctatt attgccgttt tgctagtagg
    17641 atttctagct ggatttagaa gtaatgcaac attttctgaa tggcttcttg tggtggttat
    17701 gattattcta ttttctcttg cattaacttg gctttcagta ccttttgcgt tggctgctgg
    17761 aagtattgaa ggagctggtt ccttctctta tattctgttg atgatgcttt ttgtcagttc
    17821 cgcatttgtt cctgtcgatg gaatgcctaa gatagttggc ctcttcgcag aaaatcaacc
    17881 gatgacacca attattcaaa caatcagaaa tctattaaat tcacaagctg ctggaaataa
    17941 tttgtgggtg tcaattggtt ggatggtgct aatcatcatg atttcttata tatttggaat
    18001 gaaagcttat aggagagtat aagcacctaa taataattag ttaaattcac tcgtagttca
    18061 tgtgttttga aataaaggca cattgaagag aataccaata tcagttggtt tattatggaa
    18121 aaaacattag attaaattgt taatatatta agacctcatt ctggaaggtt atgaaaaatt
    18181 gtaaaaaagg cacataaaat tacgcttttc atatcgtata agaatattat ccaactctaa
    18241 gcatacctaa aatactgaat agtgtaagtt tcccacttaa gtgttcctaa aacctagaat
    18301 ataccatgcc atttccgact tcctccacta atagttggtc caatattttt aatcctttcg
    18361 agttatacac ttcacatttt aattgaaaac catctaaatg aatgatgtat tcctttaaga
    18421 atagctattt ttttcttgct agggcttttt ttaggtgtct ttccaactag gaaaattcct
    18481 tcatagtttt gttttactac cttttctaaa tactgttcta tatgatattc agtttctcgc
    18541 acataaaaag caaaaaacaa gttaatgaaa aagcgtatgt tcagaaatct gcgatatacg
    18601 cttttttgac gaaaataaag aattgttatg tcgaatggtg cttagtgtat gttttccgcg
    18661 ttttgctacg gggacccctc attttaaaaa atacatatgt aagatttatt attcgaataa
    18721 gtggtaacag aaggctcttt tactttttat tcttgaaata acagtagaca gcgattttta
    18781 ggagaaaagg aaggttaggg gagaaatgaa tgtgtaagaa aagattaaac cttaagtaat
    18841 acgaagtgaa aattcatgga ttgatagagt tatttttttg caggaaatga attctattta
    18901 tagaagagtt ttatgtccta ttaaaggttg ttttttgtgg atgggaagat tgtattttta
    18961 aaataaatta accttttatg gaggggaata tgagcgagca aatttattat tggtctccta
    19021 ttaagcattg ggagaaattt tctaatgaag ttttgatagg agaaacgaga tatacaggag
    19081 ttatgtctga gtggtttcct gagttttatt ttcttgccca aaaggggatg acgatcagtc
    19141 agctattaga gcgcttttcg ttagggaatg aagaagaggc acaaaaaata gtagaactta
    19201 tgataaagaa tcgggtgtta gtaagtaaca tattaccccc aagggaagta ttctcaacac
    19261 aagaaaaaat ttttccgaat ccatatagcg atcagattcg cttctctaag gataatctag
    19321 ataagtatat cagtgaacaa ttaaatcgaa tgcatcctgc tgcgcggtca actggaattc
    19381 aactagaaac aaaagatgag cttcccaaca taatcaggga gcgtagatct tgtcgccaat
    19441 ttgatatgaa aaatcccgta cctttttcag agttcgcgca actgttttct actttcaaac
    19501 agaggaagga agaaaaaatc tactaccatt acgccagtgc aggtggagtt tatcccattg
    19561 atatttttgt atatataaaa ccgaaacgtg tagaagatat aaaagctggt ttttattatt
    19621 atagcccatc agagaatagt cttttgtttg taaacaacat tgaccaagta atcaaaagcg
    19681 atcatgagat aattaaccag gaattattta accagtctgc cttttcgatt tatctagtct
    19741 ataatgcgca cgcttccatg cctaaatatg gttcagatgg atatttattt gcttgtattg
    19801 aatcaggcat catcactgct acgttaaata tggtggctga gacattaaac ttgggagttt
    19861 gttccgttgg gcatatgaaa tttgaggata ttcatcgctt tttaagtttg gataaccatc
    19921 aagtatttct ccacgggatt gaagttgggt tgaaaattag cgaatagatg aaaattaacg
    19981 ttaaggggct gaagataaga atgtatatca aagatctgag ttcgattcat gagtataaag
    20041 gggcagaatc gttttggaaa gagcaattat cttctgatgt acctgatttt tcgttattta
    20101 atagtggtta tcaaatgaat aaagacaatc tatgcgacca tgttcaagtc ataatggatg
    20161 tagagtttag tcaaagttta caaaaagtaa gtaagtcaca ggatttattt ttatttaact
    20221 ggttacaggc tgctttaagg gtttgcttgg tacattatac agaccaagaa aggatcataa
    20281 ttggggttcc tgtaatcgaa aaagatcatg aacaaagaga gaacctgaat gatttgcttc
    20341 ctataggaac tgaaatccat tcccttcact cctttaagca agtagtggag caggtccaac
    20401 aaacgacttt acttggttat gaaaatcaac attatccact ctctgaatta ttagcgaagc
    20461 tctattcaac tccatttcaa atcgttttgg gaatggaagg attacataat aagaattcac
    20521 tagaagaatg ctcagagaat gaattagcca tctggataca aagaaaagag aatgaaaaac
    20581 ataatgaatt tgaatttcaa atttcttgca agtctcattc tctttttcct ttgcaacagt
    20641 ttgctaaatc ttatctttat gttttaaagc aagtgttgaa aaaccctgat ctggctgtga
    20701 aagatatctg tatcatttcg gaagaagaaa aagagttgct agaaggattt aaccaagttc
    20761 agctgggtat aaacttgtct caaacatttc aggatttatt tgagaagcaa gtgttgaaaa
    20821 ccccagatca aattgctgtt gtttgtaata atcaatcttt gacatataga gaattgaata
    20881 agaaagcaaa tcaattggct tctgttcttc aaagtaaggg tgtatccaaa gaaagtatta
    20941 ttggagttat ggtagatcga tcagtggaaa tgatcattgg catgatgggg attttaaaag
    21001 ctagaggggc ttatctacca attgatcctt actatccaaa tgaacgaatt gaatatatgt
    21061 tacaagatag tcaagcaaaa tggttactaa gcaagcgaac agagaaagaa ttgcctcaat
    21121 ttgctggtga ggtattgtat cttgatgagg aacatctctt ccagggtgaa gaaagcaata
    21181 taaatcggga aagtgaacct aatgatctgg cttatgttat ttacacatca ggatcaacag
    21241 gaaatccaaa aggcgtaatg gtggaacaga gatccctcgt ccatttctta agcattatga
    21301 gcgaaaagct aaaagataac cagtcgttcc tgtttcttgc tagtgtctct tttgatatat
    21361 ctctgttaga aatatgtgtc cctttaactc aaggctcgaa ggtagtcatt gctacagagg
    21421 gacagtttgt aacaaaagaa ttggctcatt tgatcaaaga acataaggtg gatttatggg
    21481 aatcgacccc atcgcgaatg gaattgattt tgagtgatcc agaaggagca gagtttctaa
    21541 gagatttaaa gttcattttg ttagcaggag aagcattttc aattgatttg attgaaaaaa
    21601 ttcgaagcat cagcaaagcg caaattttaa atatctatgg tccgacagaa acaaccattt
    21661 gtgcagcggt aaaagatttg agtactgcca aagaagtgac gattgggaaa cctaatccca
    21721 attattattc ttatgtattg aataaatata gtcaaatgaa accttgggga ataccgggag
    21781 agctctgtat ttctggagcg gcggtagctc ggggttatct tggtaaatct aaattgacag
    21841 atgaaaaatt tgttccgaat ccttttgtgg cgggagaaat gatgtatcgt actggtgatc
    21901 tcgtccgatg gctacctaat ggagaacttg aatatctcgg tcgaatggat catcaggtga
    21961 aaataagggg atatcggatt gaattagggg aaatcgaggc tgagctaaag agacatccag
    22021 agataggcca agctattgtt gttgatcaga tagatggaaa cagaaaatcg ttagctgctt
    22081 actatggatc ggataagaag atcccttttg aagagctcag aaaatatcta agcaataaat
    22141 tgcctgaatt tatgattccc gaaaaaataa ttcaggtaaa agagattcca ctgaatccaa
    22201 atgggaaagt ggatcgaaaa agattgttgg atttaactca aatagatcaa atctccatcc
    22261 catatgtcgc cccacgaaat caaatcgaac agaaattggt gcaagcatgg gaaaaagtga
    22321 tggagatcga gcggatcggt attcatgatc acttttttgc cttaggagga gagtcgatta
    22381 aggcactaca gattatcaac ttattaggaa aagaccatct gaaagtaagt acaagggata
    22441 tttttaaata tcccacgatt gctcaactta gttcttgtgt agaagtggag cagaaagaag
    22501 aaagcctaga taaaacacca atccgtgtta aagatttgtc caagccattt tccttaaccg
    22561 aagttcagac agcttacatg ttagggcgta attcgcagtt tgaattaagc ggcatttcac
    22621 ctcaaacgta ttttgaatat gaaacaaaat tggatatcaa tcggctttcg caaagtttac
    22681 aaaaggtaat tcagcgccat tctatgttac gagctgtgat cttgccagag ggaaaacagc
    22741 aaatcttaca agacgttcct gattatcaga ttgaaataga aaatctcatt ggtttagatg
    22801 agggaaaaca aaatgttcga ttgcaagaag aacgttctcg aatgaccaac catgtatttc
    22861 ctttgggaca atggcctttg ttcgaattga aagcctttct cttaaaagaa gacacttatt
    22921 tgttatgttt tcgatatgat gctttattga tggacggggc aagcatgaac atcgttggac
    22981 atgatttgtt gcattattat cacaaaccag atcaaagatt ggaatctctt tcttttgatt
    23041 ttcaagatta catgtgcatc tatgatgaaa tggaacaaag caaagaatat aaaaaagcaa
    23101 aagattattg gacaaacaag cttcctgact ttccatttgc tccttctcta ctgttaaaaa
    23161 aggatccaga agagattgct acccctaact ttcaatcact tactaaaatc ttggacaaag
    23221 ataaatggac gaagttacgg aagctggcac aagagaaaga agtaactcct tccgctctcc
    23281 tttgtacgtt atatggagaa gtgttggcct actggagtaa tcaacgtcga ttggcaatta
    23341 atctgactgt atttaaccgt tatcctgttc atgaagaagt agagcagatt gtaggagatt
    23401 tcacgtcact catcttgttg gacgtggatg tgaatccaga gcgatctttc tttaccagag
    23461 tggagaaaac tcaatcgact ttattagatg gacttgaaca tcgtcattat gatggagtta
    23521 gctttattcg agattttact cgatatcacc aaatgagacc aaaagcagtt atgccaattg
    23581 ttttcacctc gatgctagca ggcgcgggtg cttttgcttg ggagcagctt ggctctctcc
    23641 gccatatcca tgctcggact ccacaagtgt atttggataa tgtggtaatt gaaaaaaatg
    23701 gagagttatt gatcagctgg aactatgtag aagaattgtt tgatgttgat gtgatggaag
    23761 caatgttttc tcaatttgtc gatttgttgg aacaattggt gaaacaaaga gacgtaacct
    23821 ctttacaagt gaaaaaatcg gatcagtctt taattgagca gtacaatcag acaacagaaa
    23881 aaatactttc cactaccttg tatcaattgt ttgcagacca agtaaaacgt acaccagatc
    23941 aagtggcagt ggtctttgaa caagagtggt tgacttactt ggaccttcat caacgctcca
    24001 atcaagttgc tcactatttg caagaacaag ggattagtct aggtgacagg gtgggtcttt
    24061 tggcacagag acgggttgat acgattgtta atatgatagg gatattaaaa gcgggtgctg
    24121 cttatgtacc gatcgatccc gatcatccac cagatcgaca aacatatatc ttagaaaata
    24181 gctcgtgcaa acttttgttg gagcctggtc tttataaaga gaaacattta tcatcatatg
    24241 caacagaaga tttgcctagc attgctggtc tggaagatat tgcctatatc atctatactt
    24301 caggaagtac cggaaaacca aaaggagtta tcattactca ccaagcggtt tcaaatacaa
    24361 ttcaagatat caatcaaaaa tatcaggtga atgaagacga tcgcattatc ggtatctcct
    24421 ccatgtgttt tgacctgtct gtatacgata tttttggagc gttaagtaca ggtgcaatgt
    24481 tggtaatgat tcgggatccg agagacatgc aagaactaat ccgtacggtt gaacgcagag
    24541 ggattacgat ctggaataca gtccctgcaa tcatggattt ggcagtagat caggtaggtt
    24601 ctcattttga aaatgcttcc ttgcgtttgg tcttacttag tggagattgg attccacttc
    24661 ctttaccaga aaaaataaaa cgacatttcc cgatcgcgga agtaatttca ctgggggggg
    24721 caacagaagc atcaatttgg tcgatttatt atccagtcaa acaggtggaa gcacactgga
    24781 acagcattcc atatgggacg cctttggcaa accagacgta ttatgtgctg aactacgata
    24841 agaaaatgtg cccagttggt gtgatcggtg atttatatat tgggggagtg ggtcttgccc
    24901 aaggatattt gaatgatgaa cagaaaacga acgaagtgtt tgtgtcccat ccagaccttg
    24961 gtcttattta taagacaggg gattgtggca ggatgcatcc cgaggggtat attgaatttt
    25021 taggacgtta tgattaccaa gtcaaaattc agggatatcg agtagagtta gaagagatcg
    25081 cccattgcct tctcacttac aaacaagtag accaagctgt agtgattgac cagacagatg
    25141 agaatgagat aaaattttta gtcgcatatg tagtaactga gcaggatatc agtacaacag
    25201 aactacgaaa atatttgcga gaccacttgc cagagtacat gattccttct tattttgttt
    25261 atttggagcg actacctttg acccctaatg gaaaattaga tcgaaaggcg cttcctgctc
    25321 cagagaaaca aaaaaatgag gtatatattg ctccaaaaac tgaaatggaa aaaagattga
    25381 ccagtgtatg gcaagaagtg ctcaaagtag accaaatcgg agtaaatgat catttctttg
    25441 ccttgggtgg cgattcgatt aaggctattc aagtttctgg acggctttat gtccaaggat
    25501 ttcagttaga ccccaaaagt ttatttgact tccctgtatt cgatgacatg attcattcta
    25561 ttaagagaat agatcgacct tcacactcac aaacagatga tataaacaaa aagaaagaaa
    25621 ataaagttat atcactgaat gttagagata aacagcttaa tcaacatacg cttaacaaaa
    25681 tacaagaaaa aatgccggat ctaaaaatag aacgaatcta tccattggcg cccttccagc
    25741 aagttattta tgaacatgct gtaattgaac ccgataccaa tgcttatttt gaacaaacga
    25801 tttggacact tgaggggaga ctggatgtag atctctttat tcagtgtttt caacaattag
    25861 ttgatcgtca tgattctcta agaacgatca ttatgcgaga tgaacaagaa caaccttggc
    25921 aagctgtgtt acatgatgtt caaatgattt cagaggtaca aagcttgact gagatgacga
    25981 gacaagagca gcaggaatgc ttagaccagt ggatgagtga aaatttaggc cgaggattca
    26041 ataatgatga gctcatgacc cgtctctgtg tctttcaact aaagaataac gaatataagg
    26101 tagtttggag tgcccatcat ctattatgtg atggttggag tgtcagtatt ttgttagacg
    26161 aattattcca actctatgaa gcaaaaaatg caggaactaa agtggaatta cctccagtaa
    26221 aaccttttca aacattcatt gactggactt tagcgcaaga ctatgagaaa gcacgccgtt
    26281 tttggcgcga ttatttatca gggtacaatc ggaaaattag cattccaaaa aagaaggtac
    26341 caactcaaag taaagggtta agctttacat ttctggattt aacgttagat gaggatctaa
    26401 ccaatcagtt acggacattt gtaacccaac accatgtaac catgaattcg gctttactag
    26461 ctgtatgggg tatattgctt ggtaaataca atggaacgaa agaagtagta ttacccaatc
    26521 tggtatcagt cagacctcct gaggtggaag ggattgaaaa tatgtttggt ctgttcacaa
    26581 atgttttgcc tatccgagta gcttgggaag aaacgcaatc ttttgtggat ctcctgcaaa
    26641 aagttcaaca agaaacattg aaatgtaatg agtatgctta ctattcactt gttgagatcc
    26701 aaaaacaaag tgagttgacc gaccagttga ccgaccatct ttgggtgttt gaaaactatc
    26761 ctacaaatcc atccattttc tcttcaaatg agaacagaaa ttttaccatt acagattacg
    26821 aagttgttga tgagccgcat gtgaagtacg gaattatatg cttccctgaa gagaaactta
    26881 caatgaaatt tggatatgat caaaatatct atgaagcgga gcaagtacag gaaatattga
    26941 atcacctcca tgcattaatc aaaacgatcg tttataatcc aacacagaca atcggcgatt
    27001 atcaattata aaaaatgaaa aggcgagcaa caactcgcct tttaaaattg aataggagtg
    27061 aaataagtgt cggaaaactt gcagttatca gccgaaaaga tgcgtcagtt aggatatcaa
    27121 gcggttgatt taatcattga tcatatgaat catttgaaaa gtaaaccagt atctgaagca
    27181 attgatagtg atattctcag aaaaaagctg acagaatcga tcccagaaaa cggagccgat
    27241 ccgaaagagc tccttcattt tcttactagg aacgtgttta atcagattac ccatgtggat
    27301 catcctcatt ttttggcttt tgtaccgggg cccagcaatt atgttggagt agtagcagat
    27361 tttttagcaa gtggatttaa tgtatttccg acagcttgga tagcaggcgc aggtgctgag
    27421 caaatcgaat taacgacaat caattggtta aaatcgatgt tagggttccc tgattcggct
    27481 gaagggctat ttgtaagcgg aggttccatg gctaatttga ccgcgcttac tgtagctagg
    27541 caggtcaagc ttaataatga catagaaaat gcggttgttt atttttccga ccaaactcat
    27601 ttttctgtgg atcgggcact aaaagtattg ggtttcaaac accatcaaat ttgccgaatc
    27661 gaaacggatg aacatttacg aatttcagtc agtgctttga aaaagcaact aaaagaagat
    27721 cgaacaaagg ggaaaaaacc attctgtgtc attgctaatg ctggaacaac taattgtgga
    27781 gcggttgatt ccctcaatga gttggctgat ctttgtaatg acgaagatgt atggctacat
    27841 gcggatggag cctatggagc cccggcaatt ctcagtgaaa aaggaagtgc tttgcttcta
    27901 ggaattcatc gtgtcgattc cttgacgttg gatcctcata aatggctttt tcagccttat
    27961 gatgtgggct gtgtactcat tagaaacagc caatacttaa gcaaaacatt tcgtatgatc
    28021 ccggagtata ttaaggattc ggaaaccaat atagaagaag aaatcaattt tggagaatgt
    28081 ggaattgaac tttcgcgtag atttagagcg ttaaaggtgt ggctgtcttt taaggtgttt
    28141 ggagtggaag cttttcgcca ggcaattgat catggcatca tgttggctga acaagttgaa
    28201 acgttcttag ggaaagcgaa agattgggag gtggtaacac ctgcccagtt aggaattgtt
    28261 acttttcgtt atatcccttg tgaattagca tcaacagata caatcaatga aataaacaaa
    28321 aaattggtgg gagaaattac tcgcagagga tttgccatgt taagtacgac cgaattgaaa
    28381 gagaaagtgg ttattcgact ttgttccatc aacccaagga tgacaacaga agaaatgctc
    28441 caaatcataa tgaaaatcaa agcattggca gaggaagtaa ggacatcgta cgaacatctt
    28501 atctcggttc cgaaactttg aaatgctggg aaataagtgg tttttaacga tgaaacataa
    28561 gattgaggac tcacgcatca tttggggaaa ttgttcgttt atccgtgttt tagacatcaa
    28621 acaaccgatt gcctctacat gaaggagttg gttgtttgat ttgttttttt acatgaatgc
    28681 aaaagggttc gctagggaaa acgccccacg aaccctgtgt tttttaaata ttaatcttgg
    28741 tgcctaatat agcttttaga aattcactta aaggttgatg ataagtgggt aaatccataa
    28801 actgattttc caaatgttct tctaagtcca atttctcgat ggcattttct ccttttcgca
    28861 ctctgacgac ggggtgaata tggacactct cctccggttg tccaggcact cgaggaatgt
    28921 ttaaaggatc agcaaactta tggatatctc catactctaa agaagcggca agtaacacct
    28981 cgtcctcttg caaaggtgca ttttcaaact cgataatcgt ttggtaacca aaaatattcc
    29041 acatgccggc ttcatatttc atcacatata caataaaccc tggttgcaaa taaggatcag
    29101 aagcctctgt aagttctcct aggatatgtc caacaacttc ttcgtttgag atcatgagat
    29161 tttttattgg gaattctagc cgatctgcta ttttataagc gagaacctta ctgttatatc
    29221 ggaagccgtg tataaaaccg ctggatgttt ttcgataatc taaaccatgg gtttgagtgc
    29281 cagcgaagaa cagattcgaa acctctgttg attcgaaaac acctgatata gaaggatatt
    29341 tcttgttaat aatcttaagg ttaagatctt tcactagatg gtctatattt gaacggaaac
    29401 ctgttgcagc aatgatttcg ttaaagaata atacctcttt ctcatcctct gcatgcttat
    29461 agtgaacggt gacattaaag ccttcatcca ctttttcaat atttaggacc tcacaatcta
    29521 ataacgccgc ctgatgtttt aactgatagt tatccactag caatgaatta actgctctaa
    29581 catctccaac atagtgggtt ttatatgcca ttcgggtaga atgacgactt gcaaccatga
    29641 ttaggttggc ttcatttaat atctcttgta cgcattccat tccactgttc cctttgccga
    29701 tgatcaatac ccgtttatca cggtagtgct ctttcttttt catctcatga tatggagtag
    29761 tatgttctaa acctggaata ggtggaggat ttggggtcat ccctgttgcg attacaagaa
    29821 acttagaata caattttcca ttgtcagtct ctacctcaaa ataaccctgt tccgttttgc
    29881 gagtcgcttt ccacattgta ttatacataa ctggcaattc atattctgct accaaatcgt
    29941 ttaacatttc tactaatgct tcgcgtcgag gaaagaactc acgactgtaa ttcctcatca
    30001 tgattttctt ttcttttgtt aataaactat tccagtcaaa tctctctgag aaacgactct
    30061 ttggcggttt tccagtataa agcttattat tactgattaa ttggccatga acggggtatt
    30121 tggtgtagaa tgcacctgcc tgttttccag actcaatcat caataaatct agtttctgat
    30181 tatattcatc agagagctct ttcaaagaca acgctacttg aagaccaccc ggacctgccc
    30241 caacaacaat aacatcatgt aattttccca tgtaaatccc tccattataa ctgcaatcct
    30301 aagattgttt tgaaaatggt tttaaatcta gaacattttg attttctttc gggttttctg
    30361 gataaaaaat attaaagatt ggcattgcca tgatggttgt aaccagtgtc attaatacta
    30421 aaatggcgaa aacttgaggt gtaatgattt tgtatgtcat tccgatgtta acaaggataa
    30481 gcaccattaa acctcgtgca ttcattagca tcccaatcgc ggacgcctct cgccaagaat
    30541 atccaatact tttcatggcc agtgcacatc ctccatattt acccgcaatc gatgcaacaa
    30601 gtactaccat tgcaggaatc agaagtgaca tatcattaaa aattgttgtg aagtttgtat
    30661 ttaatccaga ataagcaaag aaaataggca atagcaaagt aattacaaaa ggctggaatt
    30721 ttgactgcaa ttcttgtaaa aaaaccttat ttcttggcat cgacaaacct acgataaaac
    30781 cgccaaacac agaataaaca ccaacatagt cagtaaacca aattgcaaca agaaggagca
    30841 aaaggactaa ggagaaatga ttcatcgaaa gcgatccctc tttttccact ctttctccta
    30901 aacgcgttaa ccacttcttt ccaataagaa gcataaaaca agcgaataac gcaccgaaag
    30961 taatagcagt tattcctgct aatacgcctt gtgcttgggc taatgcagta attaatgcaa
    31021 ctaaacacca tgctagtgca tcatcaatcg aagcagcaat taaagctaat gtaccaaagt
    31081 gagatgtggt taaattccgc tcttgtaaaa ttcgcgctaa catcgggaaa gccgtaagtg
    31141 atagagcaga ccctatgaat aatgcaaata ggtatatatt cacattagga agggatagct
    31201 ttgaataata aaggattcca accatgattc ctaatagaag cggaacgatt attccagatg
    31261 tagagagaat cgtgcatttt ttaattaggt ttcctgtcag tttcttctca tctacttctg
    31321 ctcccacaag gaacatatac atgcctaaac ctatattgct gagaacatat aaaatgcttt
    31381 ttatatctgt agtgaataga aaagacataa attgaggggc gaatatccct aaaaatgaag
    31441 gtccaatcaa aattccggct atcatttcac caaccacttt gggttgccca atataacgag
    31501 ctaaattacc acagatataa gaagctacta atactaaaat caaagcaggg ataaaactta
    31561 aaaacaactc catattactg cccaagtatg attaactcct tctatagatt aatttttttc
    31621 ttatccattc tcatacttta gccagctttt gtcttgtttt aggcaagaat ctatccattg
    31681 taatcaagcc ggcgtctgaa ctgcatttct tttatttctg gaaaatatac cccccagtat
    31741 aaaggtaacg ttgtcaatat cgcgaaatac ccttcctcct ttcttatgta aatatttaac
    31801 accctatata atttatataa cattttaaaa aatccttctg ctatttaata atttgttaac
    31861 tattttaaaa ggttcttctg ctatttaata attgttaacg aaaaccataa ttttatctac
    31921 cttgaaccga agttaaaaag tgttgtgaaa tatcgcaata taaccaaaaa aggagatttt
    31981 agaatttctc catttgaata ttggacggta taataaaaag ctgaagagta tcttcagctt
    32041 ttttctttgt tgattctctt tctgagaatc gctctatatt ccgttaagat ggacagtcag
    32101 acacttaaat tttaaatcag ttgtatagac atagcatctt tgcacattaa tcttattatt
    32161 ttcatagtga atttatcaat aatgattatt gcatgtcagt ctgttctact aaaccagttg
    32221 aaaattttca attttatcaa tatagccaat ctaaaataaa ctatttatta ttagggggga
    32281 attataatta aagctttctg tttagggtac gctgggtctt caaaaacaat atttaagtaa
    32341 tggctgggga agacaaataa tatcgaattt atcccaccta ttgtttattg tcagtacatt
    32401 gacaataaac aaagtaacaa ccttttgtta tttaatcaac atactgacta aatttatagt
    32461 tgaatctctt atgttttctt ataatgcatt ttatgtaaac taaatttgta tatagtatgc
    32521 atttaaaata agcataattc cccagtaaaa atctacgtgt aatataccat tttataaaat
    32581 gatatatcat tagaaatgag gatgatgtaa tttgataaaa ggaatatacg aagcacattt
    32641 acctgttaaa gatttggaaa attcaataga cttctatagg agattaggtt tggaacttgc
    32701 ttggcacgac gaatttacag ctttcttttg ggttgataaa ggacgaagtt ggctaggttt
    32761 atgggaaggg gatgaatata agacgcctta tcatcctgca ttgcgtcata ttgcttttga
    32821 agtaacatat gaggatttaa agacatcagt agaatggtta aatactctcg gaatcaaagc
    32881 tgaacctgtt aatccaaacc aaccgataga tccttttata cgcccaaatc aaggtaacgg
    32941 tacagtttac tttaatgatc cagatggaaa cagtttggag ttaatgtgtt atatagaagt
    33001 acctgaacac ttaagacata taactaacaa actttccttt agtgaatggg aagagattaa
    33061 taagtgagaa catgtgcctc gaaaaaacgg gctgtctatt tgatagacag cccgtttttt
    33121 gtaaagttga ttattacagg gtcatttgat gactataacg aacattatgt gaactgaaaa
    33181 tgaataatct atgcatagtg aagtaatggg attatgcaaa attctattaa ggtaaataat
    33241 caaattaaat aagaaatgaa tggaggaaga aaaatgaaga taatagaatt accaattgaa
    33301 tatgaattcc atagacaaaa aaattgtatt tatcctagct taattatact gaataatgaa
    33361 ctaaccttgg tcgatacagg gtataccaac tttttaactt taatcgaaaa tgaaattctg
    33421 aaaaatggat atgaaatgaa gaatttaaaa aatataatta ttactcacta tgatgatgat
    33481 catataggtt ccttatatga ttttaaagaa aagtatcctt ggattactat tatagctagt
    33541 gaaattgaat caaaatacat tagtggtgaa ttgaaggcag aaagattggt tcaagccgaa
    33601 gaaatgctag aaaatatgtc aaatgaagat atggaatttg gtaaatggtt tatacaacaa
    33661 ctaaagaatt tgaagcctgt tttaattaat aagaaagtac atgatggaga tatgatttta
    33721 gataacgaat gtagagtagt agcaacacca gggcatactt cagggcatat ttcattatat
    33781 tttccaaggt tgaaaagtat aattacaggt gatgcagctg ttaaagagaa tcatgaatta
    33841 gtcattgcta atccacagtt ttgtttaaat attgagaaat cccaacagtc tctgataaag
    33901 attaaaaatc ttaaagctga aaattactat tgttatcatg gtgggaaatt cacgttataa
    33961 tcgcaggata aacgatgata ctctttatta tttctctctt taaatttttg tctttggagt
    34021 aaagatatca tattcttaat ctaagataag tattttcaat tcaatagaga actttaataa
    34081 ggagggacat gatgtcttta aaaggtatat gtattaagta ttatgagttt gggaacccct
    34141 cagatgtttt acgtatagag gaagtagacg ttccattacc tcaagaggga gagttgttag
    34201 ttaaaatgga gatgagtcct atcaatccat cagatattat tccgattaca ggggcatatg
    34261 ctaaccgaat cacagtacca agcatacctg gttatgaagg agtagggatt gtagaggatg
    34321 tcggaccttc tgtttcgaag tggtttattg gcaaacgagt ccttcccttg agaggacaag
    34381 ggacttggca ggaatttgtc acatcgccag cagaattagc aattgtattg cctgaagata
    34441 ttcataatca tatagctgca cagttatata ttaatccaat tacagcgtgg gtcatttgta
    34501 atcaagtgtt aaaacttaaa ccggatgata tcctccttgt caatgcgtgt ggatcctcta
    34561 tagggcgtat atttgtccaa ttatctcaga ttataggatt ccagcttatc gctattactc
    34621 gaaatgataa acacacagcc tccttgttag agataggagc ttcctatgtt attaacacag
    34681 aagtgacatc tctaaaggaa gctgttatgg atttaacacg gggaagagga gctacagctg
    34741 ctattgattc tattggggga atagaaggaa ctcatttagc cttctgctta caaccgaaag
    34801 gaatcctttt aagtattggg ttgctgtcag gagttcctct gaattatcga gaaattatgg
    34861 aacgtacgca aacacaagca gagatctttc atcttcgtca ttggaataaa aatatctctg
    34921 taaaggaatg gcacgccact ttttatcaac ttatacaaat gattcgagat gacactctac
    34981 aacttagcca aatctctcaa tccttttcgt tagcaaatgt tcatagagct ctcactgaat
    35041 caagaaaagt ttttctaacg atgaactaat aaagatatag aatacataaa taaagattta
    35101 ggtccttcta tatggtataa agcaagaaca ttcattgtat gttattaatt tgtaaatggt
    35161 tagggttttt gttaacttac ttataatgac tagtccttaa taaaaaggaa tcctttgcta
    35221 attatggcaa aggattttct tatttatatg gataggggaa tacattaata atttatctgg
    35281 ttttatagac tttacaaatt cctctacctt actactcaaa actttttctc ctttaataaa
    35341 aaatcctcag taccctttat tcataagggc attaagcttt cttaacttcc ttgaattgtt
    35401 tctctatgaa ctaaaaatac atctttgata gttaacattt cccttgttaa ctatagattt
    35461 atgcctatta caaagggttt atagataatt tcacttatct gttatagagt aatagtgaaa
    35521 ggtagatgat taaagtgact ttgggtaagc ggttaaaaaa attaagagaa atgaaaaata
    35581 tgtcccaaga gaaccttgct caacaaatga atgtatctag gtgatccatt tacagatggg
    35641 aaacaaataa gaattatcac gatatggata atttgattaa actgagtaaa atctatgcta
    35701 ttacaccaga tgaattagtt aaagaagagc agatatcttg gaaaaaagct actatagatg
    35761 aagagggtga agaattttct atcttaccct ttattatagg ttttattatc ttacttgttg
    35821 gatttttttg attcaggtac tatgttaatc ataaatttcc ctctagaagt gttaaatcag
    35881 cattaaaaaa taagggataa aaatataaat aagaacccct cagtaacaat acataataaa
    35941 tagaaatccc tgtctgattt aaaagttaac ttttgaatca gacagggatt atattaattt
    36001 acaaagattt ggttaattct ttctgagata gcctttgcaa attctgaagt cgaagcattg
    36061 cctcctaaat ctttcgttgt aattccatct ttaagtgagt gatacagact ttgttcaacc
    36121 aatttaccta tttcttcaag attgttatca ttatgccgtt cagcgagcca ctccattaac
    36181 atgacagttg aaagcatcat acctgttgga tttccaatat ttaaacctgc aatatctggg
    36241 gcagaaccgt gggctgcttg tgccatagct acagttgcat ttgcattaat ggaaggagct
    36301 aatccaagac ttccaacaag ttcgcctgct aggtctgaaa gaatatctcc atacatattt
    36361 tctgtcacga tgacatcaaa ttctttagca cgacgtacta aatgagctgc catcgcgtca
    36421 atatggtaat catcgactgt tacttctgga tactgtttcg caacctcacg acaaacattt
    36481 aaaaataacc ctgtacttaa tcgaagaaca ttggctttat gaacgatggt tactttttta
    36541 cgacgcttca tcgccatttt aaaggcagca tgagcaattc gttccacagc ttttcttgtg
    36601 aagacacctg aagtcacaac aacgtcttct gtaatttgcc attctccatg gcctgcaaac
    36661 atatttcgat cggcataaaa accttctgta ttttcacgga agataactaa atcagcttct
    36721 cctactacgc ttttaatccc tggcatggtt ttagcagggc ggatgttagc aaataaatct
    36781 agtgtatgac gaagagcacc acttggatta agtttcacct tatgttctag tggataagca
    36841 gcagaatcat gaggaccaag tatccatcca tgagtatcct tcaaagcatt tgtagtgaat
    36901 tctggaaggg gatcattata ttgttttatt ccttcccatc ccataggtaa atcaatccaa
    36961 tcaatatcta ctccaacctt atctgcagct gttttaaacg catcaactgt agcgcttaca
    37021 atttcagggc caattccatc tccagctagt actcccaaac gataagtggt cattttttaa
    37081 caatcctttc actatatagt agggtgattt aatagtcctg taataacttg aactttatac
    37141 tattaatgta atatgaatat agaaattaat aaaatattat ttttttatgt ttataaatag
    37201 aaatttttaa tctctaattt taaagggagg actttaatgc aaaatatagg gtattaaaaa
    37261 ataaacatca tattagttac gtaggtgaac ctaaaaataa atagggcgat atttagaatc
    37321 ttataaacta agttaataag aaagcaggct ctctatattt caaagtatta ggtatatacc
    37381 aaacactaca acgaacttaa actagtaatc atcctctacc taaaataaac ttagatagga
    37441 atttaatatt gatggtactc ttgaataaag cgaacaaact cttttaccat ctctaattct
    37501 agaagttctt ccctatataa gatacgtgta ttccatatta ttggggattc cttcgcatct
    37561 ttaagaggaa ttttgtgtag ctcatcatgg tcctctagta caatacttgg agcaatacaa
    37621 taacctaatc cattaaaaac cattctttta aggtggagat actgctggaa cagtcagtag
    37681 aaagttggac atcaagggaa actatgtgtt gaaagagatt gaaacaggtt taccctcagg
    37741 actaaccata ggacgccata tgttaatagt tttgaaatca gatcgtttcg gaggagaaga
    37801 atttctgtct cttgccatta aacacctaag aaatctctca cactaaaatg aaggagagga
    37861 gatagtaatt ttcttctcta atatatcttt atgtacagaa tctctaaaag catattcata
    37921 ctttttaatt taattaccgt ccataaaagt ttaccttaag gaaaagaaaa agcacaaact
    37981 cgttgttaat cacgggtttg tacttttatt acttccttga aaagatatat gtaaactagg
    38041 tttacatata gtatacattc taaaaagaaa aaatatgata aactttccat atgcaaaccg
    38101 cttttattaa tataaaagga gagtgtgatt ataatatgaa gaggaaaaaa tatattgatt
    38161 tgagtcatac cattcaagat ggcattataa cttataaagg gcttcctgct ccaatcattt
    38221 gtgattattt aagtcgagaa gaatctcgaa aacattatgg agaaggaaca gaatttcaaa
    38281 tcggaaaaat agaaatggtg tctaatacag gaacttatat tgatgttcca tttcataggt
    38341 atgctaatgg aaaagatcta tcggaaatac caattgataa gatggctggt ctagaaggaa
    38401 ttatcgttca tattgatgaa aataaaaaag agattaatga agacgtgttt tataatcttg
    38461 atattgaggg aaaagccgtc cttattcaca caggttggga tcaatattgg aatacagatc
    38521 aatactttga aaatcatcca tatttaacgg agaaagctgc ccaatattta gtggataaaa
    38581 gagctgcttt agttgggatt gattctgtga atatagatga tacgtcaggt aaagatcgtc
    38641 ctgtacatac cactttatta gggcaagaaa ttctcatcgt tgaacactta tgcaacttaa
    38701 aacaaatttc aactgaaaac tttttatttt atgctgtttc cccaaaaatc aaagactttg
    38761 gaacttttcc agttagagcc tttgtagaaa tttcaaatta actatagtta tacaacatag
    38821 tttgttgtat tggaaacatc ttaaaaacta aaggagaatc cttgataata aaggattctt
    38881 cgttgattct agtgctgata atcaacgtta tggtgattaa tcaatataga attttctgta
    38941 ataagaagaa aacctttgct cagtatgagc aaaggttttt acatatgggg acatacgtta
    39001 atattatgaa tggtttcgta gtttcatata caaatataat tatatagctg aacctttgtt
    39061 aaaggtacga caaggggggt aagtaggtgg gttttttcta ctataggagc aggttagaat
    39121 tagcgatatc ttgtatattc gagttataat accaagttag agggatatta taaggttatt
    39181 ctgaaagggg ttatattgaa tgaagaatag caataatgat attcaagata tgattcacta
    39241 tgttaagggg aagagagaag tttttcaaca gaagttgtta tcagaagcag taaatgttgc
    39301 agaggttatt aacgatattc taaagcaagg taatattgat ctcttaaaga atgctgaaaa
    39361 attagttgtt tatatcttag aaaacaacga tcaagatatt gttgcatttg ctagacagga
    39421 aggtgttgct tgggcgcaac attcgcttac tctagctttt aaacttgagt gggttcaggc
    39481 gataagaaga tcattatgga aaacaatata tgaataccaa tctgaattca acttacctag
    39541 cattagggaa gatttttttg agttagagaa acgaattaat aataacattg atcagtttct
    39601 caatacattt ttcctaagct attcggattt taaagaccaa ttaatccata ggcaaagaaa
    39661 aaatgttgaa catctatctg tacctattat tcctattagt cctaccgttg ccattctccc
    39721 tttaatagga accattgatt cttatcgaat ggacacgatt gaagaaaagg tattaactga
    39781 tattgcaaga acccgtattc atacattaat tatggattta tcaggtatta ctgatatgga
    39841 agtggttgtt atcgatcatt ttcataaggt actggatgga atcaatatga tgggatgtaa
    39901 ggcggttatt accggattga gaccggaact ggtgagagag atgattcatc ttggcattaa
    39961 tttcaatcaa aaggccataa caaaaggaac actacagcaa tctttaaagg actatttact
    40021 gtaacattta atcatctact gtagatttaa aataaagtcg ttatgcttat aaaaaagttg
    40081 tgtcgtttga aaatgaaatt aattattgac aaatctaaat tttctatata ttattatttt
    40141 caattaaata ttagcaagca aagattggaa atagtagaag gtttataaac tttcagagag
    40201 ccggtggttg gtgagaaccg gtagttattc cctttgaact catccaagag ctactccctg
    40261 aacataacaa gtaggggacg tcggttttct accgttacaa ggataggtgg tgatagctgc
    40321 cgaaaaagag tggattaatt atgtattgat tagtcaatta gagtggtacc gcgagcaaag
    40381 cctcgtctct atatttttat agagacgagg ctttttttat tgattaatat aacaaaggag
    40441 tgtttctgaa atgatgaaga aaattttggt gtttgacacg actttaaggg atggagaaca
    40501 agttccagga gcaaagttaa atctatatga gaaacttgag gtagcacagc aactaaagag
    40561 gctacaagtc gatattattg aagtcggttt tccttcatcc tccactggtg attttaatgc
    40621 tgtgaaagag attgctatga aagtaggaaa tacagacgaa attatgatca cagctttagc
    40681 tagggcagta aaatctgata ttgatgctgt ttataatagt gtgaaatatg ctaaaaaccc
    40741 cttaattcac attgttttag gtacttcaga tattcatgta gaaaagaagt ttgggaaatc
    40801 gaaaagtcaa atattagata ttggtgttga tgcagtaaaa tacgcaaaaa ctttactacc
    40861 agatgttcaa tattcaacag aagatgcgtc tcgctctgac tttgaatact tatggtcgac
    40921 gattgaagcc gttgtaaaag caggagcgac tattattaat gtaccggata cagtaggata
    40981 tgcagagcca gaagaatttg gtgaattaat ctttaaacta aatgatcgct tgaaaaattt
    41041 gaatgataaa atacttttaa gtgtccattg tcataatgat cttggtatgg cgactgccaa
    41101 tacgttagct gcaattaaaa atggtgcgga taaagttgaa tgtacgatta atgggattgg
    41161 tgaacgtgca ggtaatgcgg ccctagaaga agttgtgatg gcggtcaata cacgctcatc
    41221 agtctataaa gcatttacaa atataaatac aaaagagatt atgaatacat ctagattggt
    41281 aagtagcttt atgggtcttg atgtgcaagt aaataaagca attacaggag ataatgcttt
    41341 tgcacattct tcgggtatac atcaagatgg gttattgaaa tctagggatg cctatgaaat
    41401 catatctcca tttgaagtgg ggttagatga tatggaacta attttaacgg ctcgttctgg
    41461 tcgccatgca gtaaaaaatg cgcttaagaa attaggtttt aatcagttga ccgaaacaca
    41521 attggaagga atatttgaag cttttcttga attagcagac acaaaaaaag aagtgtataa
    41581 tcatgatttg tatgtcttag ttgagaacta ttacaccaga cacaatattc acaatcaagg
    41641 tatggtacat tatagtgata atttctatga actaatggat atacaagtga ttagcaatcc
    41701 aatttttccg tctgcaagtg tgaaaattaa aaaggctaat caaatactga aaagtagtgc
    41761 ggttggttct ggtcctattg atgccttata ttctgctatt acagaaatta gtgatttaga
    41821 tattaaattg attgaatata atattagcag tgtatcaaga ggtaaagaag cattagggaa
    41881 agtgaaaatt caggtagaat ataaaggtga gaaatatact gccaaggcaa cagatacgga
    41941 tattatgaaa gcaagtgcat tagcatatat caatgtaatc aatattattt tagttgatag
    42001 tttactgcca attaaatgaa aatttaataa tattttaggt tttaattaga tctcctcatt
    42061 gtaaataagt tgatttgtta gggggtaatt attcaactat aatgtttctc ttagtgcctt
    42121 taatatgttt tcgtctttta cacctttaca ccatttatac tgaattcttt tgtataaaat
    42181 gaaaaccatg atttactgta catgatttag ctgctttgta attttaaggt ttttgttttt
    42241 ttgatataat gatcactatg tagatttacc ttttaataaa taggaaagtg gattgggata
    42301 tggaaaataa tgtttttgaa caaatggcaa aaagatatga tacagaagaa agaatggaat
    42361 tagctaaaat tatagttaag gaagtaagaa cagaattacc aaatagtaaa tcaaagtctt
    42421 taatagacta tgggagtggt acgggtctaa ttggtttaga attatcagat ttagtagatt
    42481 ctattttgtt ggttgattca tcaaaacaaa tgttggaggt tgcgaaagct aaaatttctc
    42541 aaaaagaaat tactaactca aaggtacttt attcagattt tactcaagga actcctgacc
    42601 tcaaagcaga tatagtttta atgtcactag tccttcttca tattccagat actaaaaaaa
    42661 ttttacaaga attgtttaac gttttaaatg atgagggcaa gctaatcatt attgattttg
    42721 ataaaaatca taagatcaat cattcgaaag ttcacaacgg ttttttagat aaagaactga
    42781 aaaaaatgtt atccgaagtt ggatttaaat caattaaaat taagacattc tatcacagta
    42841 atcgtatctt tatgaatcaa gacgcttcaa tgtttatatc tagcagtata aagtgatttt
    42901 tgttttttaa atttcttagt tcatataatc tcgattagta aaggaagcag tcatattaag
    42961 gaattaagtc actttttatc tttctctttt ttatgtgtat aaagatgaac tcccttgagc
    43021 gcctaaaggg tggtggaaat aaaacgtcat aatatatgcc atcaaaaaaa taagactgtc
    43081 ccttgtttgt gagggagtct tatttttttg gtgttcttat gtgaaatttc gcatcagaat
    43141 tgtacagatt aagtaaggtg aaaacctcca ttttgtgatc cgtagagttg gtacctactt
    43201 aacttgcagc tgtatgttta tcttccattt cgtcaggttt tgcatatgta acataggtac
    43261 ctgccatcaa atcatgcaga cttctcttat ctttacggaa aacaaccata aaaagactca
    43321 caattaaagc aatacctaat gtaagactat aaacaattcc ggctacaaga actcgtaata
    43381 gcatcgctcc aattccaagc ttctttccat ttacttttac gattctaaca ccaacgattc
    43441 gttttccgat tgtataccct gaccataaaa taggtacagc aacggtatag ataaccccta
    43501 aaattgagat aacagggtca ttttcattga attctcctgt aagtaaaaaa acaataaggg
    43561 ttaaaggaat actgacaatt acaccatcta ataggttgcc taaaaagcgt atccaaaatc
    43621 ccgctggttt tatcacatga ctcattttat atttcctcct tttttgtaca ataccattta
    43681 tcaatataaa taggctcgta catgatcgta acatggatat acgtgtagat aaaaaatata
    43741 aaatatttaa aatttattca tatttcctct tttgtaaaag gggtgaagaa atgacagatg
    43801 taaaatgaaa gttatttgat attgatctgt ctaataagtc tctattatat aaagttaacg
    43861 tatctagggc tgttttattt ccttctcatt ccaaaaaata agatattttt tgcagtaaaa
    43921 gttatgctgg tcattgattc actactatgt agtttaatag atttaaaaat atggggataa
    43981 aataatcatt aagctgactt cataattcat caattttgat ttttgtcaaa tatctaaata
    44041 gaccttcccg cctgcaactt ctatggtaga aatcgtttca tttattgata gaatcaaaga
    44101 tcgtatcaat atctaatgag gaattttagc ttccggtgag ttcatgtatc tttcctcatt
    44161 tattattctt acttgtagaa cttaatatat ttatgtttat tggtgtaaaa cacacaattt
    44221 tttcatagaa gtatacatag atttatattt ttttaatatt gataattata aatattaaaa
    44281 aatatcgaaa ggaggtcggt gcataaagtt ttgttgttat tttgataatt attaaaatag
    44341 aaagtcgatt atgtatattt ttgaaggcga aaaaattcat caataataac cggaatgtta
    44401 cgacaataaa tggaggtcgt tgaaaaatga attttgattt aacgaaagaa caagagatga
    44461 tacgtaagtt aattcgggat ttttcggaag cagaagttgc tcctggagca gatgaacgag
    44521 atcggacggg agcatttcct tatgaaatgt tttcaaaatt agcagagtta ggaatcatgg
    44581 gtcttccatt cccagaacaa tacggtggtg gtgatgctga cacgatcagc tttgccattg
    44641 tcgttgaaga gttaagccgt gtttgtgcat cctcaggaat cacatattca gctcatattt
    44701 cattaggggg agaacctctt aatttgtttg gtacccatga gcaaaaagag aaatacttaa
    44761 cgcccatttg tacaggagag tcatttgggg catttggttt gactgaacca aatgcaggat
    44821 ccgatgccgg aggaacacaa acaaccgcag ttattgatgg ggaggagtgg gtcattaatg
    44881 gctcaaaatg ttttattacc aatgcaagct atgccaaaca tcttgccgtt acggccgtaa
    44941 cagatcgctc aaaaggaatt aatggaatta gcgcatttat cgttccaacg aacgcaccag
    45001 gatttactgt tatcaataat tacgaaaaaa tgggtcttca atcctcaaat acaacagaat
    45061 taatcttgga aaatgtaagg gttaccaaag ataatctgct gggaacagca ggagagggtt
    45121 tcaagcaatt tttagctact ttggatggcg gaagaattgg aatcggggca atggctgttg
    45181 gacttgcaca gggagcttat gaaaaatcac ttcagtatgc aaaggaaaga aaacagtttg
    45241 gaaaaagtat atcaaacttc caggcaatcc aatttaaatt agccgatatg gcaatgaata
    45301 ttgaaattgc tcgaaatatg gtttacaaag cagcctggtt gaaggatcaa ggccgagtat
    45361 ttaaaaaaga ggcagcatac gcaaaattat ttgcttccga aatatgtatg cgtgcatgtg
    45421 atcaagctgt tcaaattcat ggtggttatg gatacatgaa agaatatcaa gttgagcggt
    45481 tcttccggga tgcgaagctt ttggaaattg gggaaggaac atctgaagtt caacgtatgg
    45541 taattgcaaa acaaatagga tgctgaatac atttttgtaa cggctttcaa aacataataa
    45601 aggagtaact ccatggatat caatggaatt ttacaagtgg ttgcaaacag taaacttatt
    45661 tttcctaaca aagaaaaggt acgctctacc tccattggaa gcatagaagc ttttcaagaa
    45721 cttcttcgac aatcccaaga agatcctgcc gccttttggg atagcgcagc ccgtgatctt
    45781 gtatggtatg aaccttggaa tgaaaccatt agtggacaac tccctgattt tcgttttttt
    45841 gtcgacggca ttagcaaccc aagtgtcaat ttacttgacc ggcatatagt taatggggcg
    45901 ggcaaccgga cagctctcat ttgggagggt gaaaacgggg acacaaaatt ttacacctat
    45961 aatatgcttc ttgcggaagt aaatcgattt gcgaatgttc ttcggtcatt cggtgtaaaa
    46021 aaaggtgatt gtgtagctgt ttttcttcca aatctcgcag aagcatttat tgccgtgtta
    46081 gcgtgttttc gtattggtgc tatttacaac actattttct caggttattc cgaaaaatca
    46141 ttgaaagacc gtctcattag ctttgggcca aaagtagtgg taactgcaga tgcaacagaa
    46201 cgtcgaggta aagccattcg attaaaagaa aaagtcgatt acgttgcacc aactatcccc
    46261 tctgttgaag cagtcattgt tgtcgatcgt ttaggtttag aggttcaaat gaaagagggg
    46321 cgtgattact ggtggcacga gcttacaaaa acggcaagca tcgtttgtga acctgagaga
    46381 atagaagcga atgagagtgg gattgtgttc tatacaagtg gtacgacagg aaagcctaaa
    46441 ggtgtcgtcc attctgggat ggcttttgtc actcaaaatt acacatatgc caagtatcat
    46501 atggatcacc acaatgatga tgttttctgg tgtactgctg atatcggctg gttaacgatg
    46561 catatttggg gtattactgg tgctttagcg aatggggtaa caaccgttgt ctatgaagga
    46621 gcagttgatt atccagaaaa gaatcgcttt tatcaaatta ttgaaaaata ccgggtgaat
    46681 aagttattta ccgccccaac tgcattgaga atgttaaaaa gtatgggaga aaaaccatta
    46741 gagcaatttg atttatcttg tcttgatgtc atttctcttg tgggagaacc ttttgatact
    46801 gaaacatggc attggacata tgaagtttta ggaaagaaaa aggtatatat caataatact
    46861 tgggggcaaa ccgaaacagc gggatctcct atcgcaggag cagcctggct gacgccaatg
    46921 aaacctggtt cctcaggtac tcaattttta ggtgcagttt ttgatgttgt tgatgaagaa
    46981 ggcaatccag ttaaaactgg tcagttagga aacttagtga ttagaaaacc ctttcctatg
    47041 atgtgccgta cactttggaa agaaccggag cgatattacg catcctattt tagccaagta
    47101 gaaggcagtt attatgccag cgatcttgca ttggtagatg aagatggata tttatgggta
    47161 gttggccgtt ctgatgacgc atttaatgtg gcggggcatc ggttaagtac gttggaaatg
    47221 gaaagtgctg tacttgaatg cgaaggtgtt tttgaatgcg ctgtcattgg gattcctgat
    47281 gaaataaaag gagaagttcc tttagtgttt gcccgtctgg ctgatggttt tgaaggcacc
    47341 aaagagataa tagaacggat aaataataat attatccaac aaattggtaa gattgccagt
    47401 ccaaaatcaa taattattac taatatgtta ccgaaaacag taagtggaaa aattatgcgg
    47461 cgtttattaa aagaaattgt tgcaacagga aaggtagctg gtgacattac aggacttgaa
    47521 gacccatcaa ctgttgtaga aatacagaag atcgttgctg ataaatgatc agctatataa
    47581 tgttttattc gggccagtca tttgttcgga aaatgatcgg aaaatggctg gtttcatcta
    47641 atctttctct ttgtaatcac tagattggca gttaaagatg aaggtgtaga tagattcata
    47701 tctctctata acctaaaaat ttaagcttta tgaggatacg caaagaacgc attaaataaa
    47761 ggatagaaag ggtggaaagg atgttcaaaa aggttttgat tgctaatcgt ggtgaaattg
    47821 ctgttcgggt aatccggaca tgcaaggccc tagggattac tacagttgct gtacactcag
    47881 aagctgatgc ggatgctcca catgtaaaaa tggcggatga tgcctattta attggaggtt
    47941 cgcgtgtaga agaaagttat ttaaacatcg ataaaatttt agaagtcgcc cgtttaacaa
    48001 aagcagaggc tattcaccct ggatacggcc tgctttccga aaatgccgaa tttgctcggc
    48061 gctgtgagga ggaaggactg atattcattg gaccttctcc aaaggttatc tccaaaatgg
    48121 gcagcaagat tgaatcacga aaagcgatgg aagaagcagg agtcccattt gttcccggga
    48181 ttacctaccc tttggcagat gcagaggaag cggtagaagc ggcggaccgt attggttatc
    48241 ctgtgatgct aaaagcttcc gctggaggag gcggaattgg aatgcaggtt gtccatagcg
    48301 gggatgaaat ccgcaaagca tttgcgggga accaaaaacg ggctactgat ttctttggcg
    48361 atggtgccat gtacgttgaa aaatttgtgg aaaaccctag gcatattgaa attcaaattc
    48421 tagcagacgg atttggcaat accgtttatc tatgggaacg tgaatgttcg atccaacgtc
    48481 gccatcaaaa agtcgtcgag gaagctccgt catcctttct ttctgaaact acccgcagca
    48541 aaatgggaga ggcggcagta aaagcggcaa aatcaattgg gtataaaaac gcaggaacaa
    48601 ttgagttttt agtagatgaa gagcaaaatt tttattttct tgaaatgaat acccgtttgc
    48661 aggtggaaca tccagttaca gaagaaatta caggtttgga cttagtggaa aaacaattga
    48721 aaattgcagg ggatgaagcg ctggattttt ctcaggaaga ggtaaaacgt gagggtcatg
    48781 cgattgaagt cagaatttac gcagaggatc caaaaacgtt ttttccttct ccaggaaaaa
    48841 tcaccaaatt agaattgcct aacggacctg gaattcgtca tgaattaggg gttcatgatc
    48901 aatcttcagt tactcctttt tatgacccaa tgattgcgaa gctcattgta aaagggagcg
    48961 atcgcgacga tgcaataaat cgtctgcagg atgcattagc agattatcat atcgaaggaa
    49021 ttaaaacgaa tataccaatg ctggaagagg tcattgctca cccggcattc cgttcaggtg
    49081 atacgacaac ggactttgtt ggaaagtatt taaaaattaa aaaagcaaat aacatgaaat
    49141 aggaggaatc atgatgagtg aaatcgtagc aagcatggca ggaaatgtat ggaaggtact
    49201 tgttaaggtt ggagatcaag tcgaagaagg tcaggatgtc gtgattttag aatcaatgaa
    49261 aatggaaatt ccgattgcag ccgaattcga tgggactgtt aaagaagtaa aagtgaacga
    49321 gggcgacttt gtgaatgaag gagacactat tgtaaaagtt gaataaatcc tcaaatcatc
    49381 ggaggaaagg ggatgaatca atgaaatggc ccacgaatat aaccattaaa gaggttggtc
    49441 cacgggatgg attgcaaaac gaaaagggtt ttatttcaac agaggataaa attgcattga
    49501 ttaatcaatt gtccgctagt ggcttaaaag agattgagat tacctccttt gtcaattcga
    49561 aatggattcc tgccctttca gatgcttctg tagttgcaac aggcattaca agagtacctg
    49621 gtataaccta tacggctctc gttccaaacc aacaaggctt ggagcgggcg tttgaagcga
    49681 atattgatga agtagctgta tttatgtcag ccagcgaaac tcataatcta aaaaatatta
    49741 ataaatcgat tagtgataca ttccctatcc tgagagatct ggttcaaaaa acccttgcag
    49801 cagggaaatc cagcagaggt tatgtttcta ctgtttttgg atgcccgtat gaaggggccg
    49861 ttgatataga tatggttata agagtttcgg aaaccttatt tgagatgggg attaaggagc
    49921 tatcactcgg agatacgatc ggtgttgcga atccaaagca agtccaagaa ttgttggaag
    49981 ttttcttaaa aaaattccca gcagataaat tagcgatgca ctttcatgat acacggggaa
    50041 cagccttagc taacgtctta gtatcgttag aaatgggtat taccactttt gattcttcca
    50101 ttggaggatt aggaggatgc ccttatgcgc ctggagcatc aggtaatgtg gcaactgatg
    50161 atttacttta tatgcttcac gggatgggaa tccacactgg agtagatcag gaaaagcttt
    50221 tatctgcatc ccaatttatt cagaagaaga ttggcagacc tttacctagt aaaagtcttc
    50281 aagcttcaat ctccaaatac aacagcacgt gtgaaaatac ctgatgagga aggtgaaaat
    50341 atggataaaa caatattagt taacaggctg gaaaacggaa tcgtgatgat tacattaaat
    50401 cgccctgaag cggccaatgc tttatccctt caaatgttag gggaactcca agaagcggtt
    50461 ctattatgta aatatgaccg gacaatccgt tgtgtagtga ttacaggggc tggagaaaag
    50521 gccttttgcg cgggtgctga tttaaaagaa cgcgcagata tggaacacgt tcaggtacgg
    50581 aagacccttt ccttgatcca ggggaatatc aatgatttag aagcattacc gcagccaatt
    50641 attgcggctg tgaatggtgt tgcatttggc gggggaacgg aacttgcact ggcttgtgat
    50701 atccgtattg cctctgaaac ggcgaagctt ggtctaacgg aaacctcact gggaattatt
    50761 ccgggtgcag gcgggacgca acgtttaccg agattaatag gaaagggaag ggctaaggaa
    50821 cttattttta cagcgagacg tattgatgca gcagaagcct tagagattgg attagtagag
    50881 tatacggttc cttcaaatca tttgatggaa aaagctttgg aaatcgcagg gcaaattgtc
    50941 cggaatggtc caattgccgt cacacaagca aagttcgcca ttgataaagg ctatgatgtt
    51001 gatattaaca ccggtcttgc cattgagcaa agtgcctatg aagtgacgat tccatcgaaa
    51061 gatcgtttag aaggattaca ggcctttaag gaaaaaagaa ctcccatata tggtggagaa
    51121 taagaaaacg ggattaatag aggaggaaag acaatggata tgaaacctct acaacaaata
    51181 cttgaagaaa gagtagaaca gattaaaaag ggcggccctt ctaagtatca tgaaaaaaac
    51241 acagaacaag gcaaactttt tgttcgagac cgtttaaaac agttattcga tcctggcttt
    51301 gaactagagg atgcgctatt tgcaaactac atggcggggg aacttcctgc cgatggcgtt
    51361 gtgacaggga tggggaagat taatggccag gttgtttgtg tgatggctaa tgattcaacc
    51421 attaaagctg gttcctgggg atcacgaacg gttgagaaaa tcattagaat tcaagaaaca
    51481 gctgagaaac ttcgtgtacc attaatttat ttagtagatt cagcaggagc gcggattaca
    51541 gatcaggtag aaatgtttcc tgggcgccgc ggggcaggca gaatttttta caatcaagtg
    51601 aaactatctg gaaaagtacc gcaaatttgt cttctgtttg gtccatctgc cgcaggtggt
    51661 gcttatatcc cggcgttttg cgacattgtt atcatggtag ataaaaacgc atcaatgtac
    51721 cttggctcgc cacggatggc cgaaatggtt atcggggaaa aagttacatt ggaagaaatg
    51781 ggcggtgctc gcatgcattg ttcagtatca gggtgcggtg atgtactcgc taaaaacgaa
    51841 gaggaagcca ttaccattgc ccgcaattat ctttcttact tcccggcaaa ttttttagaa
    51901 aagccgccgg ttcatgaggc agcggcacct aaacaaatga agagatcatt ggaagagctg
    51961 attccggcaa atcaaaactc tccatttaat atgcatgacc ttgttaatgg aattattgat
    52021 gaaggttctt tctttgagat taagaaacta tttgctaccg agcttattac aggtcttgcc
    52081 cgcatggacg gaaaacctgt cggcatcata gccaatcagc ctcgtgtaaa gggcggcgtg
    52141 ctgttccatg atactgctga caaagctgcg aaatttatta atctttgtga tgcataccat
    52201 attccgttat tgttcctggt tgatgtgcct ggatttatga ttggcacaaa ggtagaacgg
    52261 gcaggaatca ttcgccatgg tgcaaaaatg atttctgcaa tgtcggaggc aagtgtacca
    52321 aagatctctg ttatcgttcg aaaggcttat ggtgcaggtc tatatgccat ggccggcccg
    52381 gcgtttgaac cagatgcttg tctggcttta ccttccgctt cgattgccgt aatgggacca
    52441 gaagcagccg tcaatgcagt gtatgccaac aaaattgctt cattacctga agaagagagg
    52501 gctgcattta tcgctgaaaa gcgcgaggaa tataaagaag atatcgatat ttaccggctt
    52561 gcttcagaaa tggttattga tggagttatt ccggcaaact cactgcgcga cgagttaatt
    52621 aaacgctttg aagtatattc ttcaaaatat ttaatctttt ctgagcgtaa gcacccagtc
    52681 tatccagtat aatatttggt tctatacgag gagggtgtcc tgtgaagaaa ggtaaaatag
    52741 tagaatcttt tgcggaagcg attcatgatg aatcattttt ttaaaaaatt ttttatccga
    52801 aacataaaaa tgatccaact ctttaacacc caaaagagat aaatatcaat tgagcttcta
    52861 gacgcctgga aaagtataat taaaggacaa gaaaaagctc aaattcgtta ttattcaacg
    52921 tgtttgagct tttattactt tcttaaacat gttttatgtt aactactttt gtatatcgta
    52981 tacagctaaa aaagtattaa ataggcctta ttagaaaagc ttaaataaaa gagtgattta
    53041 tagactctat aggttacctt tttatttttt agagaataaa gtaccttcta cttagggata
    53101 gggggaagaa atattaacca taaaaaaata ataaataaac tagataaaag ccatgaaacc
    53161 caaagtttcc atttatgaat gggtaataaa gtattaggtg agaaagtaac cctctttctc
    53221 taatatttta cgctacatag aaacccctgc acctatagga gtagggggat tttttgcttt
    53281 ccctaacatg ctttatgtaa actaagtttg tatatagtat gattattgat acctctttta
    53341 ttagtaatga gttgttataa cgaatggaga ttaatatggt acccttttat taaactctct
    53401 taccgtcaaa agtataaaga agagaagaag tcagcataaa aggaaggttg atactatgtt
    53461 catagaattt attgcgacaa cgttagaaga tgctctatta attgaacaat cgggggcaaa
    53521 tcggattgag ttagtatccg ctttaacaga gggaggatta acaccaagtc actccttaat
    53581 cgaagccgta gttaaccgtg taagcattcc agtcaatgta atggtaaggc cacatagcca
    53641 atcattttgt tactctcatg acgacttttc gatcatgaaa aatgatataa gaataatccg
    53701 ttcattaggt gcaaatggtg ttgtactagg agtgttgaat gagaaacatg aagtcaacca
    53761 acacatactt gaagagttat tgagggaatg caatggtata gaggttacat ttcatcgagc
    53821 aattgattgt acaatcagtc ccgttcaagc ggctaaaata ttagcccaat acaaagaaat
    53881 aacaactatt ttaacttctg gtggaaataa tgaattttcc agtcgcttgc aaaccattca
    53941 gaaaatgaaa acagtatgta agcatatttc aattttggtt ggaagtgggt taaatacaag
    54001 caatattctt tctgttcatt caacagtaca aacggggcat tatcattttg gtacggctgt
    54061 gagaaaaaac catagtctga tcgaaggaat tcatctagaa aaagcgaaag aaatggtgca
    54121 aatattaaaa gatgaagaga gaaaatcagt ataaaaatta ttctatgtga tgcagggatg
    54181 tcaacaagga taatggattt atattttgat acaagagatt atccttaaat aagggaacta
    54241 cttataattc gtgttatgtt aactgaaaaa ttatatttta taaaatatga tagagcttcg
    54301 gttcacaaag gttttatgtc tttgatggcg atgttctttt ttacagagat acgttagcaa
    54361 tctacatcgt tacaagatgt agataattga gggagggata tgtctatctc ttctctaatg
    54421 aaaagcgctg caaaccatac aagtaagggt tgcagcgctt tttttatgat ttaaataggt
    54481 tatgcataag tttcttcact ggagcgttta ttccctgtat aaataaaata aagtgcaaca
    54541 agcatgaata gtagtgcaaa aaaacgtttt aagtcaaagg ggatgatgag actattaaac
    54601 caaccaaaat gatcaatcag aatactaatg acaagctgac caacaattcc tgctatattg
    54661 gttgcaataa cgccgatttt tggaacagct gtaataacga aaagtccata tagagtacca
    54721 agaaatgcag cacttaattg ccacttcggt gcttctagta ttttaagtac atttccttcg
    54781 ccaaagaaaa gaattaaaat ggctagaaac atggatcccg ttataaaagt taaaagagtc
    54841 gcttcaatgg ttccagcttt tcgactaaat ggaccattga ccgatgattg agcgctcaac
    54901 atgataccgc ccaataaagt gaatagaacc atgattgttc ccatgatgtt taatcctccg
    54961 caaatatttt ttctttatta attctcgatt tcttactacc aagccaacca taatgttcaa
    55021 tcaccatact catgactaat tgaccgatta tgacagcaac catcgtaata ccaaccccaa
    55081 caaagggaac actgatcacg atggaagtta gataaacgac gcctaaaaaa tcctcccatt
    55141 agtgaccatt taggtgcttc cacagtatag gaaagtttcc ctttacctgc gaatagccat
    55201 attaatccca caatgatgga ccccataaaa aagttataaa aactcgtttc caatttccct
    55261 atggtttttc ctaattcggc atatatacct ccctcaaagc taagggctgc tcctgctaat
    55321 aaggcaaata gataagagag aataacgcat tactagatcc tcctattttc gtatattcaa
    55381 atatctaaaa aaatcgatgt atttattttt aaagacagaa actgaacaat ctagatttct
    55441 gtctttaaat gtttagcgaa ctcttgaata acttcttcct atcacatcca atagtccatt
    55501 tactataacg aacggatatt taagtaaacc aaatttctgc atcatgtaaa tcattctctt
    55561 tggtagattc acgccttgct taggaaaagg ctcctctgaa tcctttaacg atgataaaaa
    55621 atctagttta tcttgataat gatgtagata catgtggtag ttctataacc aacattttag
    55681 attagtttta tcttaatgtt tagaaaatcc agttataagg agctttatcc tttttattga
    55741 tatcccctag taacggaagt cgctgtaaca tattttgtaa gttataagca tcccatggaa
    55801 aatgttctgt aatccctagc cctacaacat catgggcttt ggctacatct tgaaggaccc
    55861 gtataatggt ttccatacta gaacttgttg gaactcgatc cttcatttcc tcataagtag
    55921 ctggattggc gactaagagg gaacgaaatt ctcttaaatc gagaacgtct aaatcaaaat
    55981 gaacgataac cttagaaggt ttacgtgaat ccagccactg aagtacctta gaactgtctt
    56041 ctttaatatc atctggagtg gcgatattca tttttatatc ttgtaacggt ttagagttaa
    56101 gtgcttccat catatcgttc aatcctacaa acaatacttg ttctggttta aatgaacgag
    56161 gtacttctgc gacgaattcc ttatccccga tacccaacaa attagcaagt acgtgagcat
    56221 gatggtttgg aaactcctca ggaatggaaa catcagggtg taaatcaacc cataacaaag
    56281 cagtgtctcc atcatatttt tcgtttaagt atgcaaaagg agcaagttct acaccacaat
    56341 cccccccaag aacaataata ctatcaggac tgtgcttttg aattacactt ttagcagacc
    56401 ttgcttgatt taataagaca ctcttagcaa caataccctg ctctatttca aggcttgaat
    56461 ctaaatcgat aggtacttct tcaaatggac cgttcgtttt aggtgcaagc cagtttaaca
    56521 aatgagctcc aagtacgtac ggagggttgt ttccaccttg ccattgtggc atgagtaatc
    56581 gaagagtttt actttttgct gcttctttat gttctttcat ttagcatctt cctttcaaaa
    56641 tatttataag aactatgcaa caaataataa accctatagt aactataggg tcaagggtga
    56701 actatttttt tagtactctt aattctgtga ggaactgttc ttctcttaat gagctatagt
    56761 tggtaggaag agaaatttga tatacttttc catcggtctg gatgctattt gattcaatat
    56821 aatggtaaag ttcttgataa tatgaatcat aatgtttggt agaccaatca aatgaaatac
    56881 atacatattc acctgatgga atagtatcta actgaatatt ttttccttct atatctacct
    56941 tttctccttt acaaatagtc gtataaatat tgttgcaata aatatcccga gaatctttat
    57001 aaggctttaa atcataaatg aacccataat agttatcgac catgtctcct ctttcttcta
    57061 aaacatccac caactttcgg aagtataaat ctgattgatc atgaggatta acttgaggcg
    57121 tcgctacttt taaaatggtt tgttcctcca tatatcgaaa gtaaactatc cctttttctc
    57181 tgttacatat ttctaactgt tccttaagct gattctttct tctatgaagt aatcgccgag
    57241 cacgttcgag gttatccatt tcatcctcaa taacactttc ttgctcctca agaaaagttt
    57301 gcatatgttc agggttaccc gagatgatac gcctgatttc ttccaatggg gttcggatat
    57361 attttaaata cttgataata tctaaataaa aaaactgttt aatatgataa tatcgatagc
    57421 cattatcctg atctgtgtaa tgaggcttga aaatgccaat cttatcataa tagcgcaaag
    57481 tttgaatcga gatgttattg agacgggctg tttccccaat tgaaaaatat tgtttcataa
    57541 accttatcct ttcttatccg ttagctttta agaatctttc tcttactata cacgattata
    57601 aattaaattc tccataaact aacttgagaa gatagataac ctgctgaaag tgagttttag
    57661 gcatacaatg acgaatgcgt tacttttgta agaattaata taagaatttt taagcttaat
    57721 tatataaatc ttaatggtgt agagaattta cctatcttat aacaattatt aattgacagt
    57781 aaaaaattaa cattacaaat aaaaaaaaca aaagaattga ccctattcct actatagggt
    57841 ttatgatttg tgacgtagat ttataaatag tcaaagatag aaaagaaagg tgaatgttat
    57901 gaaaaacaat aacagaatat gcgatatact tggaattcaa tatcccattg ttcaagcagc
    57961 catgagctgg atcacggatg cgaaaatggt agcagccgtg tccaatgccg gaggaatggg
    58021 agttttaggt cctaatgctg gttcgaattt tgagggatct aaaaagatta gtacggaaga
    58081 aagacttcgt aatgaattac gcaaaactaa atcactaacg gataaacctt ttgctgtgaa
    58141 tattttctct ccagaagagg ggacggatga tacgtacaca caaaccgttc taaatatatc
    58201 tttagaagaa ggaattcaaa cattcctaag tgttggcttt gtcaacaaaa aattatttag
    58261 acaaattaaa gatcataatg ccacgttaat tcaccgtgaa ttgactccta cacctgaagc
    58321 tgcaaaaatg gcagagtctg aaggcgcgga tatcattatt gcgacgggct atgatgaagg
    58381 cggatggatt cctcagaacc aaattggaac cttttccatc gtgccaacga tcgtagacgc
    58441 agtagatatt ccggtaatgg ctacaggtgg aattaatgat attcgtggtg tgagagccgt
    58501 gtttgctctt ggcgcggaag gtgtctatgt aggaacgcgt tttattgtat cggaagaatg
    58561 tcctgcttca gacattacaa aacaagatat tattcgttca aaagcgaagg acctggtttt
    58621 tgtgtcgtca cttcaacgtt ccacacctca taaattggct cgagagttag agagtatgta
    58681 caaaaatgga atgtcccctg acgaggaaat gagtcttcgt ccaggaatgt tagaaggaaa
    58741 gctagatgaa ggaatcgttt ctgtaaacac ggctattgat gttattacgg aagtaaagag
    58801 ttgtgaagac atcgtcaaag aattaatggc agactttatt aagtaattca atactgattg
    58861 ttaaatcgta tataaaggag gattttcttc agacattaag tctagattgt tagttaactt
    58921 atttgtcgat agaggaatac tcccctttcc aacagaaagg gcttatattc acctcgaaaa
    58981 tttttaatta agtctaagat tgtccaaaaa gatgattcgt caatcataac aagtgatcaa
    59041 gtcaagggtc gattataatt aatattcttt ctttaatgcg tcttttaatc tcagtgaaac
    59101 aacgagaaat ccgaatgaaa gaactttata aaccattatt tgaaccctgt acattccctt
    59161 gtggaataga aattgataat agaataatta tggttccaat ggcaacaaag tcatcttttg
    59221 aaaatggaat ggttacatta gatgagcttg cttattataa aaggagaact aaaggacttg
    59281 gaatggtgat aacttctgct actcgtattg aaaaatacgg aagtcagcct ggttcaataa
    59341 gcattgcaac agacaaacat atccaaagct tatctaagtt agctaataca attaagagta
    59401 atggcacgaa agctatcttg cagatttttc atgtcggaag aatgcagact agtattgtag
    59461 aaaaaaggta tttttcataa taaagacact cttttttata acattttaac cgtttgtgaa
    59521 agttcaccta aaggaaagga aaaagcgtaa actctttgtt gctcattgag tttgcgcttt
    59581 tttactacct ctaacatatt ttacgttaac tctgtctgta tatgatatat aagcttttag
    59641 attttaatag atatatttaa ggcctagagc aaaataacac ttgaaacaaa tgtaaaaact
    59701 ttctctactt tatttgaaca tttctttctg tctttttata aaattccctt tttagacact
    59761 ataaccatgt attagcagta taaaaaagta tactatacaa caaaaatgtg cgtacttgtt
    59821 gagctgattt atagggttta ttataaaatt gtaaacggag gttatataaa attgtatgtt
    59881 aactagttgt tagttgtacg ccatagagag aacaccttcc tttaaagggt tctctactga
    59941 atacttttac agaagggttg attttatatg aataatacaa ataaaaaaca agaaattcta
    60001 aaggcatttg catttcgtca tgccacaaag gaatttgatc caaccaagaa aatttccgat
    60061 gaagattttc aatttatttt agaaacaggt cgcttatctc caagctcagt agggtatgaa
    60121 ccatggaagt ttttggttgt tgaaaatgag gaattaaaga ataaattaaa agctgtttct
    60181 tggggagcac aagggcaaat ccctacagcg agtcattttg ttattatcct tgctcgtaca
    60241 gatgcaaggt acgattctga gtacgtatta gacctccaaa agaatgtgaa aaaagttcca
    60301 aatgatgtgt tagaaacatt aatg
//
