LOCUS       NZ_LWAI01000037        22148 bp    DNA     linear   CON 07-APR-2024
DEFINITION  Priestia endophytica strain 3618_1C 3618_1C_contig_41, whole genome
            shotgun sequence.
ACCESSION   NZ_LWAI01000037
VERSION     NZ_LWAI01000037.1
KEYWORDS    WGS; RefSeq.
SOURCE      Priestia endophytica
  ORGANISM  Priestia endophytica
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
REFERENCE   1  (bases 1 to 657542)
  AUTHORS   Lekota,K.E., Mafofo,J., Rees,J., Muchadeyi,F.C., Madoroba,E. and Van
            Heerden,H.
  TITLE     Comparison of Bacillus endophyticus and B. anthracis characteristics
            using whole genome sequence analysis and microbiological analysis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 657542)
  AUTHORS   Lekota,K.E., Mafofo,J., Rees,J., Muchadeyi,F.C., Madoroba,E. and Van
            Heerden,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2016) Biotechnology Platform, Agricultural
            Research Council, 100 Soutpan Road, Pretoria, Gauteng 0110, South
            Africa
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-MAY-2015
            Assembly Method                   :: CLC Genomics workbench v. 7.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 330.0x
            Sequencing Technology             :: Illumina HiScan SQ
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003269975.1-RS_2024_04_07
            Annotation Date                   :: 04/07/2024 05:04:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,413
            CDSs (total)                      :: 5,355
            Genes (coding)                    :: 5,223
            CDSs (with protein)               :: 5,223
            Genes (RNA)                       :: 58
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 44 of 132
            Pseudo Genes (incomplete)         :: 88 of 132
            Pseudo Genes (internal stop)      :: 43 of 132
            Pseudo Genes (multiple problems)  :: 35 of 132
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:25:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 472858
            Orig. end                         :: 495006
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LWAI01000037.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22148
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="opine-like-metallophore"
                     /region_number="3"
                     /rules="(CntL and CntM)"
                     /tool="antismash"
     cand_cluster    1..22148
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(CntL and CntM)"
                     /kind="single"
                     /product="opine-like-metallophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22148
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:12148](+)"
                     /cutoff="5000"
                     /detection_rule="(CntL and CntM)"
                     /neighbourhood="10000"
                     /product="opine-like-metallophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12148
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(CntL and CntM)"
                     /neighbourhood="10000"
                     /product="opine-like-metallophore"
                     /protocluster_number="1"
     misc_feature    1132..1146
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 22.43"
                     /tool="antismash"
     gene            complement(1181..1633)
                     /locus_tag="A4U60_RS27615"
                     /old_locus_tag="A4U60_16790"
     CDS             complement(1181..1633)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002167247.1"
                     /locus_tag="A4U60_RS27615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16790"
                     /product="CBO0543 family protein"
                     /protein_id="WP_113753557.1"
                     /transl_table=11
                     /translation="MIFNILIAFILPWIVGILHLYKKDRTIIPLIGTFFCVIAFVVNEF
                     GFYYGFWRIAPFFNQKTLSALPFNLGLYPILASYLIFFIKKTKRPYLMIFSISLFTTFL
                     EMTLVLSGKVVYGNGWNTIWTFFSYIIPYIWVYWYYLHLKKLQIMN"
     misc_feature    complement(1708..1726)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.29"
                     /tool="antismash"
     misc_feature    1816..1831
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.84"
                     /tool="antismash"
     gene            complement(1878..2261)
                     /locus_tag="A4U60_RS17010"
                     /old_locus_tag="A4U60_16795"
     CDS             complement(1878..2261)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364495.1"
                     /locus_tag="A4U60_RS17010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16795"
                     /product="VOC family protein"
                     /protein_id="WP_113753560.1"
                     /transl_table=11
                     /translation="MKLAMKYVILYVSDFEKTMDFYKGILGLPVKMQQDTYVEFDTGAT
                     TLSINTRKDVKELTGLNVPEGSAPTQTFEVGFVVEDVVATIETLRQQGVTILKEPVTKP
                     WGQTVAYIADPDGHYIEICTSVE"
     misc_feature    complement(2333..2347)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.26"
                     /tool="antismash"
     gene            2548..2925
                     /locus_tag="A4U60_RS17015"
                     /old_locus_tag="A4U60_16800"
     CDS             2548..2925
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020156588.1"
                     /locus_tag="A4U60_RS17015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16800"
                     /product="DUF1801 domain-containing protein"
                     /protein_id="WP_113753562.1"
                     /transl_table=11
                     /translation="MQYEAKTPKEYFELLDDDWRKEKLLIVREFILENAPELEEGVQYK
                     MLCYGSETSKLFHLNAQKSYVSLYVGNIGKIENANKFLTGLDYGKGCIRIKKSVDLHDS
                     GLEDFVKKTIFTWRAGDDTSC"
     gene            complement(3420..4181)
                     /locus_tag="A4U60_RS17025"
                     /old_locus_tag="A4U60_16805"
     CDS             complement(3420..4181)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394409.1"
                     /locus_tag="A4U60_RS17025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16805"
                     /product="dipeptide/oligopeptide/nickel ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_113753569.1"
                     /transl_table=11
                     /translation="MNLLTVHELKKSYQAKKTILDNISFELNKGECLGLVGESGCGKST
                     LARCLLRIQPIDSGSIYFRDQAIEQFNDRQLYPYRRKIQIVLQNPSASLNPKLKIKDSL
                     IDPYAQFKNDLNLIHFSYTSKDDFIKQLLEVVELPSSLADRYPHELSGGQRQRVTIARA
                     ISIEPEFIVLDEPTASLDVISQGAILTLLTDLRKTLNLSYLFISHDLAAVKEMSQRIMV
                     MKDGKLVDQFNNEQLFNEERHSYTKELISIF"
     gene            complement(4178..4978)
                     /locus_tag="A4U60_RS17030"
                     /old_locus_tag="A4U60_16810"
     CDS             complement(4178..4978)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394408.1"
                     /locus_tag="A4U60_RS17030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16810"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_113753578.1"
                     /transl_table=11
                     /translation="MILSIEQVSISSREKKIVDNVSLSIRKGEWYALVGQSGSGKSLLS
                     QSIGQLLHPNLQIEGKIFFKGENLLEFSPKQIQTIRGQKISYIFQDYQGSFTPFRTISQ
                     HFEEYQKAHGIHDPKTRQLNAKEELKAVGLDETLYNRYPFQLSGGQLQRVSFALALLLS
                     PDLLIADEITTALDSVSGHKILELLAKRQKEKGCTILFITHDWRHVKRYATRLAVMKEG
                     EIVESGNKHRILDHPRHEYTKQLIQAAPTLGRGLPSGLPEVENK"
     gene            complement(4975..5823)
                     /gene="nikC"
                     /locus_tag="A4U60_RS17035"
                     /old_locus_tag="A4U60_16815"
     CDS             complement(4975..5823)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nikC"
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394407.1"
                     /locus_tag="A4U60_RS17035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16815"
                     /product="nickel transporter permease"
                     /protein_id="WP_113753585.1"
                     /transl_table=11
                     /translation="MKGLSMHLFNEKKPVWQGIIGLLSIVFVILVSIYTFYYLKHDPTL
                     TNLDGRLQEVSFHHPLGTDHLGRDVLTRLLLGGIQTIGYSSLALIVALIIGIPFGLISG
                     YKRGLVDRIFMRIADGFLAFPDTIVAIVLSGLLGPGIGNLVLAIVLVKWVSYARLVRST
                     VLSESQKDYVLVAKINGLSSFKIMRKHLLPHIVGNVLVLASLDLGKIILLISSLSYIGL
                     GAQPPTPEWGAMLNDSRPYFESKPELMIYPGLAIVAIVLLTNMLGDYLRDHFDVKKEIR
                     K"
     gene            complement(5820..6767)
                     /gene="nikB"
                     /locus_tag="A4U60_RS17040"
                     /old_locus_tag="A4U60_16820"
     CDS             complement(5820..6767)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nikB"
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691506.1"
                     /locus_tag="A4U60_RS17040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16820"
                     /product="nickel ABC transporter permease"
                     /protein_id="WP_113753591.1"
                     /transl_table=11
                     /translation="MVQIIVRKFLEVFIFMLFITFVSFLFIRLAPGDPVLTILNVDELS
                     VSQEQVEMLREEMGFNKPLLVQYGYWLLNFVQLNFGQSYVTGQPVIEMILTGLPATVEL
                     TSGSMIVMLAVSIPLGSLSALYRDSWIDQISRILSIIGAAIPSFWLGLIFIDLISVRFS
                     WLPTMGRDGLSSLILPSLTLGLAISSVYVRLLRSSLLDSLGQEFIRSARARGLSDKRIF
                     LAHAFRHSLPPVITVFGVSLGSLIGGVVVIEVLFAYPGIGKLVVDAIRQRDYPLIQGYI
                     LIMSAVVFIVNTCVDLSYRYLNPEMKLKETENNR"
     gene            complement(6772..8361)
                     /gene="nikA"
                     /locus_tag="A4U60_RS17045"
                     /old_locus_tag="A4U60_16825"
     CDS             complement(6772..8361)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nikA"
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394405.1"
                     /locus_tag="A4U60_RS17045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16825"
                     /product="nickel ABC transporter substrate-binding protein"
                     /protein_id="WP_113753593.1"
                     /transl_table=11
                     /translation="MVRNRDFYRIYNTFHRYIRNNFLKVGFLVIFAGLLSACENSATET
                     KNKEEGKHVHFLYNFSTNSLDPHVDSSYVPLRAGITETLVRLDEENLTIKPWLAESWEG
                     EDGQHWTIKLREDVKFHNGKQMDAEAVKASLERALKESVAVKNALKIDNIQADGYSLHI
                     TNTEPFPEFVSELVNPNVSIIDVTEGNIINKPIGTGPFALESFTPGSKLELKRYNDYWD
                     GASKLDSVTFSFNEDANARSLALKSGQVDIVYRPEVESLETLKAMDGIKVESTATFRVH
                     QMTMNMQRKSLKDVNVRRAVDALIDRQKIVDTILLGHAEVAQGPFLPSLPFAPTYENSQ
                     VGKGADVAIKHLEKAGYKLKDGKMKKNGEPLKFTLLTYSARADLPLIAQVFQSDAKKIG
                     IDVEIRQIDIPEEYMASNRDWDLATYSNLTAPRGDAGYYLNATYHPNGALNFSGASDPK
                     LTAIIDKLNQTVNQEERATLSEQAANYINEHVINSFVLHPSTIVAYNEDKVKNWVTTRS
                     EYYMITNKLDVK"
     misc_feature    complement(8481..8495)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.08"
                     /tool="antismash"
     misc_feature    complement(9050..9070)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 27.34"
                     /tool="antismash"
     misc_feature    9072..9087
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.86"
                     /tool="antismash"
     gene            9139..9972
                     /locus_tag="A4U60_RS17055"
                     /old_locus_tag="A4U60_16835"
     CDS             9139..9972
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009676614.1"
                     /locus_tag="A4U60_RS17055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16835"
                     /product="diaminopimelate epimerase"
                     /protein_id="WP_113753598.1"
                     /transl_table=11
                     /translation="MEQEINFVKLNPTQNMTILVETAHPVKAHKDIATKIMSYDSVYAE
                     QVGFIEEPINYKADAHLQMAGGEFCGNACMALAAFITSKQELKHNRVKKILLEVSGTDS
                     LVECEVKRVADEYYCQVTMPIPKEIKQTTINHEGNKLDIALVDYGEFVHIVRNVKDFNE
                     RVKEEAQSLAKSLSLTLNISLIGILLYNQDSNELEPLIYIPHLDSMIWERGCGSGTASL
                     GSYLAWKNKRETTTHVKQPGGTITTVANYQEGKLISLKIEGSVAIVAQGKAFITV"
     gene            10001..10816
                     /locus_tag="A4U60_RS17060"
                     /old_locus_tag="A4U60_16840"
     CDS             10001..10816
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     opine-like-metallophore: CntL"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016098173.1"
                     /locus_tag="A4U60_RS17060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16840"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_113753600.1"
                     /sec_met_domain="CntL (E-value: 8.7e-95, bitscore: 312.4,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNELENFLKDLNEYLERFNYLTVSYNHPGNNCSELEALINKYSHF
                     ITNIENKGVWNQLENQENCDLDQIVNHLRKKSALCVAIMEKYRAMKLLNGETEITDYFK
                     NVESCIEKEFGNFHITSDSKVLLVGSGAFPMTPILIAKRTGSEVVGVDIDDEAIELGLK
                     VIEILGTELNIRLEKTPVEYLDFTKDATHIIFSSTVKDKYIILDQLHELTNEDVVVAMR
                     YGDQLKSLFNYPSREVDKQKWNKVEDILRPHDVFDIELYKKVPKFITYI"
     gene            10832..12148
                     /locus_tag="A4U60_RS17065"
                     /old_locus_tag="A4U60_16845"
     CDS             10832..12148
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     opine-like-metallophore: CntM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010898231.1"
                     /locus_tag="A4U60_RS17065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16845"
                     /product="opine metallophore biosynthesis dehydrogenase"
                     /protein_id="WP_113753602.1"
                     /sec_met_domain="CntM (E-value: 8.5e-185, bitscore: 609.8,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDFERILILGTGPTSIQLAVSLKKQLNCYVGIAGRESVRSKSFF
                     SALKQSNKLIRVSVQNEKHRNVEGECSVDQIFKGYETVRGRWDTIILAVTTDAYIEVMK
                     QLNKEVLEHVRCIILTSPTFGSNNLINSYINDTNSNVEIISFSTYYGDTRWMPDNPSNH
                     VLTTAIKKTVYIGSTYYPSENMVLLCDIYKQLGINLAVMQSPIEAETRNISLYVHPPLF
                     MNSFSLNAIFEDIDTKKFVYKIYPEGPITQYLIRDMLSQWKEVMNILRCMKVEELNLLK
                     FMIDDNYPIRPESLSRQDIEKFPHLETIYQEYLLYIRYTSLLIDPYSEPDKNGRYFDFS
                     AVPIRKVFVNREGYLDVPRMPKEDYYRIKIIQGIARYLNLNCPTIDKFINTYESKIEEF
                     SNSQKEKLLSKAFNIQSFAEDLNMICNEIGKSSEAIKVK"
     gene            12338..13909
                     /gene="nikA"
                     /locus_tag="A4U60_RS17070"
                     /old_locus_tag="A4U60_16850"
     CDS             12338..13909
                     /EC_number="7.2.2.-"
                     /GO_component="GO:0009897 - external side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015413 - ABC-type nickel transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0015675 - nickel cation transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="nikA"
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007721793.1"
                     /locus_tag="A4U60_RS17070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16850"
                     /product="nickel ABC transporter substrate-binding protein"
                     /protein_id="WP_242447713.1"
                     /transl_table=11
                     /translation="MVCLVVLNTSDSKKTVGTDSQNNEKGIVYAASKDINDMNPHLYTG
                     SMPAQALVYESLVENTEDGIKSLLAKSWDISKDGKTYTFHLRKDVKFHDGEPFNAEAVK
                     KNIDAVQANAEKHSWIKLSTKIVDCKVIDEYTVELVLSEAYYPTLVELSMTRPYVFISP
                     KDFINGETKDGVRGYHGTGAYVLTEHKVDEYATFKANENYWDGVPKVKKITSKVLPAGE
                     TTFLALQKGEVNFAFTDDRGADSLDVEAMNQLVDSGDYQLIRSAPMNTKIIVANSSKAD
                     NPVHEKAVREAIWYAIDRKTISNDILSGTETVANTLFSHNVNYADVNLKKRNYDLNKAK
                     EILQKAGWISEDSNDVRTRDGEKLAVKLYYDSSSSSQKTQAEFIQSSLKEIGVQLQIIG
                     EESTSIANRRSTGDYDLLFNQTWGLAYDPQSTISAFTSPSSYLHTTKGIEKADELYKKI
                     DDVMVSMNEETRRSLYADILKIVHDEAVFIPISNGSVTVIAPKNLKGISFKQTQFKLPF
                     EKMHFE"
     gene            14041..14973
                     /gene="opp1B"
                     /locus_tag="A4U60_RS17075"
                     /old_locus_tag="A4U60_16855"
     CDS             14041..14973
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="opp1B"
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007721794.1"
                     /locus_tag="A4U60_RS17075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16855"
                     /product="nickel/cobalt ABC transporter permease"
                     /protein_id="WP_113753605.1"
                     /transl_table=11
                     /translation="MRCCITKKLLISIPLLLVISFLTFILINLSPQDPAEVVLHAQGVP
                     KITDELIIETKKELGLDQPFIMQYLHWLIACLQLEFGNSYITGQSVWSLIGPAFLNTLK
                     LTLVSSVFVIVLSIFLGVLCAMREGRLFDKSVRGASFFLTSAPSYWLASMIIWYFSIKL
                     DLLPTSGMDSYKSYILPVTIITISYAGIYFRIVRSSMLNNLNEDYVLYGRACGLNEQTI
                     TLQILRNSLQVSISVFCMAIPIILGSTVVIENVFAWPGLGSLSVKSILSRDFPIIQAYV
                     LLLAVSFVVFNTISDIINAAINPKLRNDL"
     gene            14974..15870
                     /gene="opp1C"
                     /locus_tag="A4U60_RS17080"
                     /old_locus_tag="A4U60_16860"
     CDS             14974..15870
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="opp1C"
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016098177.1"
                     /locus_tag="A4U60_RS17080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16860"
                     /product="nickel/cobalt ABC transporter permease"
                     /protein_id="WP_113753608.1"
                     /transl_table=11
                     /translation="MRILKNLSKDKLAIMSLIVITLTIFVGIFAPIFAPHNPKEVNMGL
                     RYASSSWEYLLGNDHLGRCILSRLIYGIRPSVLWVSVALLLSVVIGTVMGFLAGYFRGK
                     VDVVIMRICDIMLSFPGYVMTLAIVGILGVGLVNILISFVFLKWAWFARVIRTSVMQYT
                     ELEYVKFAKACGISNIRIIYKHIVPVTLSDVIVLSSSSVGSMVLQISGLSFLGLGIQAP
                     NAEWGMMLNEAKEVMFTRPELMLAPGLAIIIVVSSFNFLSDALQVALDPKLMSSKNRIK
                     GSLALSRHQIGKNEVAK"
     gene            15875..16690
                     /locus_tag="A4U60_RS17085"
                     /old_locus_tag="A4U60_16865"
     CDS             15875..16690
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006638074.1"
                     /locus_tag="A4U60_RS17085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16865"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_113753610.1"
                     /transl_table=11
                     /translation="MNILEVEHLKIQDIENGKVIVHNSSFSLKQGSCLAIVGESGSGKS
                     VTCRSIMRLNKPSLSQSGTILFKGEDLNALTEKEMRQKRGRNICMILQNGMTAFDPSCV
                     VGVHLKETLFEHFGWNKLEIERKMKSAMESVMLKNPLEIMNKYPHQLSGGMLQRLMIAL
                     SIALEPDIIIADEPTTALDTISQFEVIEQFIKLREKIGCSMIFISHDLGVVKKVGDDIL
                     IMKDGIIVERGSIQTTFSQAQHEYTNYLLSTKQVLSNNFKKIMGMNNKC"
     gene            16684..17430
                     /locus_tag="A4U60_RS17090"
                     /old_locus_tag="A4U60_16870"
     CDS             16684..17430
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015735103.1"
                     /locus_tag="A4U60_RS17090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16870"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_113753613.1"
                     /transl_table=11
                     /translation="MLIVEGIEKAYKTGGLFSKEKQKILKNVSFECKSGECLGVIGESG
                     SGKSTLGRLLIGIEQPDAGRVLFEGRSVNDRVIRLGSISAVFQDYTSSINPFFTVKQAI
                     IEPIKIKKSTKIEIENRIDYLLNQVGLASSYKEKYPHELSGGQIQRVCIARAIATEPKC
                     ILLDEAISSLDVSVQVQILKLLKELKEIYNMSYIFITHDIQAAAYICDRIIIFKNGKIE
                     ETVETSDLKNVQSAYARKLLQKLITL"
     gene            17512..18699
                     /locus_tag="A4U60_RS17095"
                     /old_locus_tag="A4U60_16875"
     CDS             17512..18699
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009676633.1"
                     /locus_tag="A4U60_RS17095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16875"
                     /product="MFS transporter"
                     /protein_id="WP_113753615.1"
                     /transl_table=11
                     /translation="MSGAMSWPFLRLYGLTLLYFSANSILNVIIPLQGETLGASNTTIG
                     IIMGAYLFTTMFFRPWAGHIIQKKGPIKILRIILVINGFALILYTITGLGGFLLARILQ
                     GVSTAFFSMALQIGIIDALPEEDRSQGISLYSLFSHIPGVIGPILALGIWQANNTSYFM
                     IVMISITIFTGIFGYSAKVDKQGDLTEINDTHQRVNMFKSFGELIKNPFLFKCSVLMLV
                     ASIVFGSITTFLPLYAMELKNGNAGVYLMIQAGTVVFARFTLRKKIPSDGKWHSSFVMG
                     TMLLLALAAQCVSFSITGGVMFFYIGAVLMGIAQALIYPTLTTYLTFVLPKGNRNILIG
                     LFIAMADLGVSLGGVIMGPIADISSYSFMYMICAILGGAMIIFAYDQRKIFVEGK"
     gene            <18821..19369
                     /locus_tag="A4U60_RS17100"
                     /old_locus_tag="A4U60_16880"
                     /pseudo=""
     CDS             <18821..19369
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003183778.1"
                     /locus_tag="A4U60_RS17100"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="A4U60_16880"
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /pseudo=""
                     /transl_table=11
                     /translation="LMAAGLSFALFLLSITEGGMTTNIEQYLFGSIVTIRTQQLYIMAG
                     VTFLVLLYFSIFKRQLYLMTFD"
     gene            19505..20065
                     /gene="dcd"
                     /locus_tag="A4U60_RS17105"
                     /old_locus_tag="A4U60_16885"
     CDS             19505..20065
                     /EC_number="3.5.4.13"
                     /GO_function="GO:0008829 - dCTP deaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009394 - 2'-deoxyribonucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="dcd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003348225.1"
                     /locus_tag="A4U60_RS17105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16885"
                     /product="dCTP deaminase"
                     /protein_id="WP_113753618.1"
                     /transl_table=11
                     /translation="MILSDKGIIKRIEEKELYIEPLTTKQIQPASLDLRLGGNYLRIRE
                     NRVGVLSLEKEIEYESVESDEIIIPSHSFLLATTMEYIKLPNNLTAFVEGRSSIGRMGL
                     FIQNAGWVDPGFEGQITLELYNANRLPLKLVKGWRICQLVFAEMDQFPNHPYVGKYQGQ
                     INTTGSRSFLDKDDEGLRKEKSQ"
     gene            20062..20952
                     /gene="folE2"
                     /locus_tag="A4U60_RS17110"
                     /old_locus_tag="A4U60_16890"
     CDS             20062..20952
                     /EC_number="3.5.4.16"
                     /GO_function="GO:0003933 - GTP cyclohydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="folE2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003348224.1"
                     /locus_tag="A4U60_RS17110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4U60_16890"
                     /product="GTP cyclohydrolase FolE2"
                     /protein_id="WP_113753621.1"
                     /transl_table=11
                     /translation="MKLPDKKERHQLFGSIAPGMKYKPTRKEEMVDLQNLSKDFLFTIK
                     KVGISNVKIPVQLQSSLPPRHQTTIATFSLTSNLSHKQKGTNMSRFLEVLERYRQQGFT
                     LNFSTLHCFLEELAQKLEQEATYLQVEFLWFYDRISPSSNLKGLNHANVKLDISYHKEK
                     GFKDDVSMTCGITTLCPCSKEISEYSAHNQRGYVKMDVNISPSHVNDELNWKEDLLDAA
                     ESNASARLHPLLKRTDEKVVTEQAYENPRFVEDMVRLVGADLYELNWIKSFTVECRNEE
                     SIHLHDACASMSVQK"
     misc_feature    21310..21325
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.48"
                     /tool="antismash"
     misc_feature    21380..21396
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
ORIGIN
        1 gttctagcta ttcgttggtc acaagagatg agttggggaa aggctattta ttatgggata
       61 ttccattcta tatctgcatt taacaatgca ggatttggct tagaaccaga taacctaagt
      121 aaatgggtgg gagatccaac cgtaaatatt gttattacat tactttttat aataggtgga
      181 acaggatttt ttgtcatcgc agatattttg gagaaacgaa gcataaggaa gttttctctt
      241 catactaaga ttgtattagt ttcgaccatt ctcctaaatg tcgtgagtac actcgtcatt
      301 tttgctttag aatatcacaa tgctaacacg ttaggtaaat taggtatggg agataaatgg
      361 tgggcggctt attttcaagg agtagtccct cgtacagctg gttttaatac cttggatata
      421 ggagaactaa cgttaagttc aaaagtttat atgatgggac taatgtttat tggagcagcc
      481 ccaggttcga caggtggggg aattaagatc acgacctttg tcttaatatt gctagcttta
      541 tgggtagtcc taacaaacaa ggaagatatc aatgtttttc aacgtagaat ccctaaatca
      601 cttatttata gggctttttc tattgctact tctgccatga tttttgtctt tgttattttc
      661 tttttactaa ccataacaga aaaaggagta gatatgtcta cgctcttatt tgaaaccatt
      721 tctgcttccg gtacggttgg actaagtgca aactttacag gagacttgag ccccgcagga
      781 cgcattctta ttacgattat gatgtttatt gggcgagtag gacctcttac cattggtttt
      841 gtgcttgcta ttcgttcaaa taaacaatca aaaattcgtt atgcagaaga aaagattctt
      901 attggctaaa aagaataacg tttatatttc gagcaaacta aataagatac tgttaaacct
      961 ctatcaaaca ttctcatttg ttcgagttga caacatgcaa aggaagaaag ttattgggga
     1021 aagctagtag ctttcttcct tatttagaat gtatatcaca tctatctttg attaacctaa
     1081 tgttacttat cggcattgaa aaacgatctt cgaatagaag atccttttaa aggaaaattc
     1141 gttccaaagt aacacaatgg cagtgtgtta ctttggagaa ttaattcatt atttgtaatt
     1201 tttttaggtg aagataatac caatataccc atatatacgg gatgatgtag gagaaaaatg
     1261 tccaaatagt attccagccg ttaccatata ccacttttcc acttaaaact aacgtcattt
     1321 caagaaaagt agtaaatagt gatatagaaa agatcatcaa gtaaggtctt ttggttttct
     1381 ttataaagaa tatcaagtaa cttgccaaaa ttggataaag tcctaaatta aaaggtaagg
     1441 cagacaaggt tttttgatta aagaagggag caattctcca aaatccatag tagaacccga
     1501 attcatttac aacaaatgca ataacacaaa aaaatgtacc aattaaaggt ataatcgtcc
     1561 tatctttttt ataaagatga agaattccaa caatccaagg taagatgaag gcaattagga
     1621 tattaaaaat caatttttcc catttccttt tttgtattta tcttctcctt atttcaaata
     1681 gtctaacctt caaaacaaag tattatatga atactctata caaatctact taccataatg
     1741 ttgattataa gaagggattt ttaaagtagg agcagggttg atcctgcttt ttaatttttg
     1801 gttgtgttaa tttttaatga taataattag acaaaaacaa aaggaaacca agatactaag
     1861 gtttccttca gcccaattta ttcaacagaa gtgcaaattt caatataatg tccatctggg
     1921 tctgctatat aggcaactgt ttgtccccac ggctttgtaa caggttcctt taagattgta
     1981 accccttgtt ggcgtagggt ttcgattgtt gctacaacat cttctacaac aaatccgacc
     2041 tcaaatgttt gtgtaggagc agaaccttca ggaacattta aacctgttaa ctcttttaca
     2101 tccttacgag tgttaattga taaagttgtg gcacctgtat caaattcaac atacgtatct
     2161 tgttgcattt taactgggag cccaagaatg cctttgtaga aatccattgt tttttcaaaa
     2221 tcactcacat ataaaatgac atatttcatt gctaacttca ttttttcact ctccttatgg
     2281 gaaatttaag aacttaaata atagcctata ccaccgtatt aatcatacta tctaatttct
     2341 gaaaattata ttaataacta taatattcat tgtgatatag tcataataaa gtaaggcgaa
     2401 tcacaaaaaa taaaaagaaa catagatctt tttttgagag cccgttgaat tatctaattc
     2461 aaggggttcc atgttgacta gatattcatt aaggctctgg tgcaaatatg tgaagaaaat
     2521 ataaaaagat ttactggagg tttgacaatg caatacgaag ctaaaacccc aaaggaatat
     2581 tttgaactac tagacgatga ctggagaaaa gagaagctat taattgtgag agaatttatt
     2641 ttagaaaatg ccccagaact cgaggagggc gtccaataca aaatgctttg ttatggtagt
     2701 gaaacctcca aattatttca tttgaatgct caaaaatctt atgtgagtct atatgtgggc
     2761 aacattggaa aaatagaaaa tgccaataag tttctgaccg gattggatta tggaaaaggg
     2821 tgtatacgca taaaaaagtc agttgatttg catgatagtg gacttgaaga tttcgtgaaa
     2881 aagactatat ttacttggag agcgggcgat gatacttctt gttagcacta cttttaattt
     2941 caaagagtat tagtagtatt ttcccatcac aaattcgtat ttatggatag agttttttaa
     3001 aaagatatca aataaaaaga agatgagcgc ccttactaca atcccgtctc atataatcaa
     3061 gttttacatc ctggtacttt aatgattaat attgagggcg tagaaaatac attaaaagaa
     3121 gaggaacgta caactaagat attagctatt gtcattaaac gtacactgca taatcagcaa
     3181 aactaacagt cagaaaaaat cctgtttctt cgaacaggat ttttttattt ctaagatttt
     3241 agttaatata aaacctattc gaggaagtaa aaaagcacaa aaccgttggt tctcaacgaa
     3301 tttgtgcttt ttcttttctg ttaatgcaag ttactataaa cgagctaata ataaggcttg
     3361 ttattaacaa ttagatttta caatacaaca gtgttgtaat aactgataga tacaactggt
     3421 caaaaaattg aaatgagctc ttttgtatat gaatggcgtt cctcattaaa taattgttcg
     3481 ttgttaaatt gatcaacaag tttgccatct ttcatgacca taatccgttg actcatttct
     3541 ttaacagcag caagatcatg ggaaataaac aagtatgaaa gatttaacgt tttacgaagg
     3601 tctgttaata aagtaagtat tgccccttga gagataacgt caagacttgc tgtaggctca
     3661 tctaaaacaa taaattcagg ttcaatacta atagcacgag caattgttac acgttgtcgc
     3721 tgaccgccac ttagctcgtg aggatatcga tctgccaagc tagatggtaa ctcaacgact
     3781 tcaagaagct gctttataaa atcatccttt gaagtatagg aaaaatgtat aagattaagg
     3841 tcattcttaa attgagcgta aggatcaata agtgaatctt ttattttaag ttttggattt
     3901 aaagaggctg aagggttttg cagcacaatt tgaatctttc ttcgataagg atataactgt
     3961 cgatcattaa attgctcaat tgcctgatcc ctaaaataaa ttgatccgct atcaatcggt
     4021 tgaattcgga gcaggcagcg agctaatgtg ctcttaccac agccactttc accgacaaga
     4081 cctagacatt ctcccttgtt cagttcaaat gagatgttat cgagaatggt tttcttagcc
     4141 tgatatgatt tttttaattc gtgtacagta agtaaattca tttgttttca acctccggta
     4201 aacctgaagg gagcccacgc ccaagtgtag gcgctgcttg aattaattgc ttggtatatt
     4261 catgccttgg gtgatcaagt atacgatgtt tattacctga ttcaacaatt tccccttcct
     4321 tcattactgc taagcgagtt gcatatcgct taacatgtcg ccaatcatga gtgataaata
     4381 atatggtaca tcctttttct ttttgccgtt tggcaagtag ttctaaaatt ttgtgtcctg
     4441 agacactatc aagcgcagtt gttatttcat ctgcaattaa taaatctgga gatagtaaaa
     4501 gtgccaatgc aaatgagaca cgttgaagtt gtccaccact taattgaaag ggatatcggt
     4561 tgtatagtgt ttcgtctagc ccaacagctt taagttcttc ctttgcattt aactggcggg
     4621 tttttggatc atgaatccca tgagctttct ggtattcttc aaaatgttga gaaatggtac
     4681 gaaatggtgt aaaagaacct tgataatctt gaaaaatata agaaattttt tgaccacgta
     4741 ttgtttgaat ttgctttggt gagaattcaa gtaagttctc ccctttaaaa aaaatctttc
     4801 cttctatctg taaattagga tgaagaagtt gtccaattga ctgggataat agactttttc
     4861 cacttccact ttgcccaaca agagcatacc attctccttt gcgaatcgaa agggacacgt
     4921 tatcaacaat tttcttttcc ctactgctaa tggacacttg ctcaatcgat aaaatcattt
     4981 tcgtatctcc ttttttacat caaaatgatc acgtaaatag tctcccagca tgttagtcag
     5041 taatactatg gctacaatgg ctaaaccagg gtatatcatt aattcaggtt ttgactcaaa
     5101 atagggacgt gagtcgttta gcattgctcc ccattcagga gttggtggtt gtgcccctag
     5161 ccctatatac gatagagagg aaatgagaag aataatttta cctaaatcaa gacttgccaa
     5221 aacaagaacg tttcctacaa tatggggaag taaatgcttg cgcataattt taaatgaaga
     5281 tagtccgttg atttttgcaa ccaacacata atctttttga gattctgata aaactgtact
     5341 acggactaga cgggcataac ttacccattt aactaacaca atagcaagga caaggttgcc
     5401 tattccaggt ccgagcaaac cacttaagac aatagcaaca attgtatcag ggaaagctaa
     5461 aaatccatcg gcaattctca taaatatccg atcaactagc ccacgtttat atcctgaaat
     5521 aagaccaaag gggattccaa taatgagagc aacaattagt gctagagaac tatacccaat
     5581 tgtttgaatc ccccctaaca atagcctagt caaaacatct ctaccaagat gatctgtacc
     5641 aagtgggtga tggaagctca cttcttggag acgtccatca agatttgtta atgtaggatc
     5701 atgctttaaa tagtaaaaag tataaataga gactaagatt acaaagacaa tggatagtag
     5761 cccaattatc ccttgccaga ccggcttttt ttcattaaac aaatgcatag aaagaccctt
     5821 catctattat tctccgtttc ttttaatttc atttctgggt tcaaatatcg ataagacaaa
     5881 tcaacacatg tatttacaat aaaaaccaca gcagacatga ttaaaatata tccttgtatg
     5941 agtggataat ctcgttggcg tatcgcatca actacaagtt ttcctatacc aggatatgca
     6001 aatagaactt caatcaccac tacaccacca attaagcttc ccaaacttac cccaaataca
     6061 gtaataaccg gagggagact atgtcgaaat gcatgggcta aaaagattcg tttatctgac
     6121 agaccacgag ctcttgctga acgaataaat tcttgaccaa gagaatcaag taagcttgaa
     6181 cgaagcaaac ggacatatac actagaaata gctaaaccaa gtgtaagcga tggtaagatt
     6241 aatgaggata gtccatctct ccccattgtt ggaagccaac taaaacgtac actaattaaa
     6301 tcaataaaaa taagacctaa ccaaaaacta gggatagctg ctccaataat tgatagtatt
     6361 ctactaatct gatcaatcca gctatcccga tacagggctg ataaggaacc taatggaatg
     6421 gatactgcca acataacgat cattgaccca cttgttaatt caactgtggc gggaagaccc
     6481 gttaaaatca tctctattac aggttgacca gtaacatatg actgaccgaa attaagttga
     6541 acaaaattaa gaagccaata cccgtattga acgagtaaag gcttgttgaa tcccatttct
     6601 tctctcaaca tttctacctg ttcttgacta acagacagtt catcaacatt cagaatagtc
     6661 aacacaggat caccaggtgc aagcctaata aataaaaagc ttacaaaggt aataaacaac
     6721 ataaaaataa aaacttcaag aaacttccga acaataattt gaaccatcta tctacttcac
     6781 atccagttta tttgtaatca tgtaatattc actacgggta gttacccaat tcttaacttt
     6841 atcttcattg taggcaacga ttgttgaagg atgtaaaaca aacgaattga ttacatgctc
     6901 atttatataa ttagctgcct gctctgaaag tgtagctcgt tcctcttgat tgactgtttg
     6961 attgagttta tcaatgatag ctgtcaattt cggatcactt gcaccactaa agtttagagc
     7021 accattggga tggtaagtgg cattcaaata ataacctgca tccccacgag gagccgtcaa
     7081 attactataa gtagccaagt cccaatcgcg gtttgatgcc atatattcct ctggaatgtc
     7141 gatttgtctt atctcaacat caatcccaat ttttttagca tctgattgaa aaacttgagc
     7201 aattaatggt aaatcagctc ttgctgaata agttagtaag gtaaatttaa gcggttctcc
     7261 attttttttc atttttccat ctttaagctt ataaccggct ttctctaaat gttttatagc
     7321 tacgtctgca cctttcccca cttgactatt ttcatatgtt ggagcaaatg gaagggaagg
     7381 gagaaatgga ccttgagcaa cttcagcatg cccaagcaga atggtatcca caattttttg
     7441 acggtcaatt aacgcatcta cagctcgtcg tacattgaca tcttttaaac ttttacgttg
     7501 catattcatg gtcatttgat gtacacggaa agtcgctgtg gactcaactt taataccatc
     7561 cattgctttt aatgtttcaa ggctctctac ttctggacga taaacaatat ctacctgccc
     7621 agactttaag gcaagtgaac gagcgtttgc atcctcatta aaagagaagg ttacagagtc
     7681 gagttttgaa gctccatccc aataatcgtt atatcgtttt aattcaagct tgcttcctgg
     7741 ggtgaaactc tctaatgcaa aaggtcctgt acctataggt ttattaataa tattcccctc
     7801 tgttacatca ataattgaaa catttgggtt tacaagttct gatacaaact ctggaaaggg
     7861 ttcagtattt gtgatatgta aggagtaccc atctgcttga atattatcaa ttttcagtgc
     7921 atttttcaca gcaacactct ctttaagtgc acgttcgaga gaagctttaa ctgcttcagc
     7981 atccatttgc tttccattgt gaaatttgac gtcttcacga agtttaatcg tccagtgttg
     8041 accatcttca ccttcccaac tttcagctag ccatggtttg atagttaagt tttcttcatc
     8101 taatcgaact agcgtttctg ttattcctgc tcttaacggc acataacttg aatctacatg
     8161 aggatcaaga gaattagtag agaaattata cagaaaatga acgtgtttac cttcctcctt
     8221 atttttcgtt tctgttgctg agttctcaca ggcactcaat aaacctgcaa aaatcactaa
     8281 aaaccctact tttagaaaat tatttctaat gtacctatga aaagtattat aaatcctata
     8341 aaagtctcta tttctaacca ttttaagtat attcctccta atacgaaata attacgattt
     8401 acattttatc gtaatcattc tgatttggca atattaatca tttcatagat tatatcttta
     8461 acttgttgtt ttgtttagga ttgaacgttt aatcctcaat aattgcaatt aaataggcac
     8521 gaggggtagg agatgagaac cttgaatttg aaagattata aaatttacct cagggataat
     8581 ggctataagt ttactctcaa acgattagaa attttatcat tttccgtaca ttatcaatat
     8641 cggtttatat cagttaagtt agttatacaa catcttcgaa aagcgtcagg aaatgttaga
     8701 ttggataccg tatatcgtaa tctcttcctt tttagagaca ttggtttaat agaaacaatt
     8761 tttcatgaag gcgaaaatct tttttgtttg aagagtaaac ttactactcc ttctcacttc
     8821 tttatttgca taaaacgttc cagtgaaaca gaattagata tttgcatcat gcacataatg
     8881 gagttttctc tccctaacta ttagattaat caccacaaat ttgaaattta tggtgtatgc
     8941 cttatctgta aaaattgact ttcctctaag aagggtattc cacaaacacc ttacagttat
     9001 attaagaatt tagcataaaa tagaaaaata ggtattgacg gtagcaaata acatagtata
     9061 agctatcctt aaatgataat cgtaatcatt actatttgtg tagcgcttag tctataaatt
     9121 agtaaaggag aggtgcggtt ggaacaggag ataaattttg tgaaattaaa tccaactcag
     9181 aacatgacga ttctagttga aactgctcat ccagttaaag ctcacaaaga tattgcaaca
     9241 aagattatgt catatgacag tgtatatgct gaacaagtag ggtttataga agaacctata
     9301 aattataagg ctgatgcaca cttacaaatg gcgggaggag aattttgcgg taatgcttgt
     9361 atggcactag cagcttttat tacttctaaa caagagctaa aacataatcg cgtaaaaaaa
     9421 atattgttag aagtgtcagg aacagattcc ctagtagaat gcgaagtgaa gagggtagca
     9481 gatgagtatt attgtcaggt tactatgcct atcccaaaag aaatcaaaca aacaactata
     9541 aatcatgaag ggaataaact ggatattgct ttagtggatt acggggagtt tgtacatatt
     9601 gtaaggaacg taaaggattt taatgaaaga gtgaaagaag aggctcaatc attagcaaaa
     9661 tcactatcct taactttaaa tataagtttg atagggattc ttttgtataa tcaagactct
     9721 aatgaactag agccccttat ttatattcca catttagata gtatgatttg ggaaagaggg
     9781 tgtggttcag gtacagcctc tttaggatct tacttagctt ggaaaaataa aagagagact
     9841 accacccatg taaaacaacc tggtggaact attaccacag ttgctaatta tcaggaggga
     9901 aaactaataa gccttaagat tgaagggtct gtggctatag tagcacaagg gaaagctttt
     9961 ataactgttt aactattcca ccatatagga gcgagaataa atgaatgagc tagagaattt
    10021 tctaaaagat ttaaatgagt acctagaaag atttaattat ttaacagtaa gctataatca
    10081 tccaggtaac aattgttcag agttagaagc actaataaat aaatattctc atttcataac
    10141 aaatatagag aacaaaggag tatggaacca attagagaac caagaaaatt gtgatttaga
    10201 tcaaattgta aatcatctga gaaagaaatc agctctatgt gtagctatta tggaaaaata
    10261 tcgagcaatg aaacttctaa atggagagac tgaaataact gattatttta aaaatgtaga
    10321 gtcatgcatc gaaaaggagt ttggtaactt ccatattact tctgattcaa aagtgttatt
    10381 agtgggttca ggggcatttc cgatgactcc tatattaatt gcgaagcgaa cagggtctga
    10441 ggttgtaggt gtagatattg atgatgaggc catagaactt ggattaaaag tgatagaaat
    10501 attaggaaca gaattaaata ttaggttaga aaaaacacct gtagaatatc ttgatttcac
    10561 aaaagatgct actcatatta tttttagttc aactgttaag gataaatata taatcctaga
    10621 tcaacttcat gaattaacaa atgaagatgt agttgtggct atgaggtatg gtgatcagtt
    10681 aaaatcccta tttaattatc cttcaaggga agtagataaa caaaaatgga ataaagtaga
    10741 ggatatatta cgtccacacg atgtgtttga tattgaattg tataaaaagg tgcctaagtt
    10801 tatcacttac atataagaag ggaagagttt tatgagtgat tttgagagaa tcctaatatt
    10861 aggaactggt ccaacatcta ttcagcttgc tgtcagttta aagaaacaat taaattgcta
    10921 tgtggggatt gcaggaagag agtctgttcg ttcgaaaagt ttcttttcag ctttaaagca
    10981 gagtaataaa ttaattaggg taagcgttca aaatgaaaaa catcgtaatg tggaaggtga
    11041 atgttcagtt gatcaaattt ttaagggcta tgaaacggta agaggtagat gggatactat
    11101 cattttggct gtaacaactg atgcatatat tgaagtaatg aagcagctta ataaggaagt
    11161 attagagcac gttagatgta taattttaac ttccccaact tttggttcaa acaacttaat
    11221 aaatagttat ataaacgata caaattcaaa tgtagaaatt attagttttt ctacatacta
    11281 tggtgatact cgatggatgc ctgacaatcc atctaatcat gtattaacaa cagcaattaa
    11341 gaaaacggtc tatataggat ctacatatta tccgtctgaa aatatggttt tgctttgtga
    11401 tatatataaa cagttaggca ttaatctagc agttatgcaa tctccaattg aggcggaaac
    11461 aagaaatatt tccttatatg ttcatcctcc attatttatg aattcctttt cattaaatgc
    11521 aatatttgag gatatagata caaaaaaatt tgtgtataaa atctatccag aggggcctat
    11581 tacccaatat ttaatccggg atatgctatc ccagtggaaa gaagttatga atattttaag
    11641 gtgtatgaaa gtagaagaac ttaatttgct gaagtttatg atagatgata attatcccat
    11701 aagaccagaa agtttatcgc gtcaagatat tgagaagttc ccacatttag agactattta
    11761 tcaagaatat ttattgtata tacgttatac gtccttatta attgaccctt actcagaacc
    11821 agataagaac ggaagatatt ttgacttttc tgctgtgcct attagaaaag tatttgttaa
    11881 tagggaagga tacctagacg ttccaaggat gcctaaagag gactattatc gcataaaaat
    11941 tatacaagga attgcaaggt atctaaattt gaattgtcca actatagata aatttatcaa
    12001 cacgtatgag agcaagatag aggaattttc taattctcaa aaagaaaaac ttctatctaa
    12061 ggcctttaat attcaaagtt ttgccgagga tttaaatatg atatgcaatg aaataggtaa
    12121 gagcagcgaa gctattaaag taaagtaatg gaataaaatg ctttttaaat cgtaataatt
    12181 acgaaataag tgacgtatca tatttattat gaagttcata ttcgcacaat aaatctacat
    12241 tggatacaga ctaagtgcac ctaaagggag agaaagaaga ttgttagtca agaaatttaa
    12301 attgggggct ttcatttttt taatatcatt tattgtagtg gtttgtcttg tagtattaaa
    12361 tacttctgat agtaaaaaaa cagtaggaac tgactctcaa aataacgaga aaggtatagt
    12421 ttatgcggca tctaaggata tcaatgatat gaatcctcat ttatacacag gttcaatgcc
    12481 agcgcaggca ttagtatatg aatcattagt cgaaaacaca gaagacggga ttaaatcttt
    12541 acttgctaag tcatgggata tctctaaaga tgggaaaacg tatacttttc atttaagaaa
    12601 agatgttaaa ttccatgatg gagaaccatt taatgcagaa gcagtgaaga agaatattga
    12661 tgctgtacaa gccaatgcag aaaaacattc ttggattaaa ctgtcaacaa aaatagtaga
    12721 ttgtaaggtt atagatgaat atacagttga attggtatta tcagaagcat attatcctac
    12781 tttagttgag ttatcgatga caagacctta tgtatttatc tcacctaaag actttattaa
    12841 tggggaaaca aaggatggag tcagaggtta ccacggtaca ggcgcgtatg ttcttaccga
    12901 acataaagtt gatgagtatg caacctttaa agcaaatgaa aactattggg atggagtgcc
    12961 taaggtcaaa aaaattactt ctaaagttct tccagcagga gaaacaacgt ttctagcctt
    13021 acaaaaagga gaagtcaatt ttgcttttac agatgaccgg ggtgcagata gtcttgacgt
    13081 tgaggctatg aatcaattag ttgattcggg tgattatcaa ttaattagaa gtgcaccaat
    13141 gaatactaaa ataatcgtag ctaatagtag caaagctgat aatccagtac atgaaaaagc
    13201 tgtacgtgaa gctatttggt atgctattga tcgaaaaaca attagtaatg atattctgag
    13261 tggaacagaa accgtagcca atactttatt ttcacataat gttaattatg cagatgttaa
    13321 tttgaaaaag aggaattacg atttaaataa agcaaaggaa attttacaaa aagcgggatg
    13381 gatttcagaa gatagtaatg acgttagaac aagagatggc gaaaaattgg cagtgaagct
    13441 ttattatgac agcagttcct cttctcaaaa gacccaggct gaatttatcc aaagttcatt
    13501 aaaagagata ggtgttcagc ttcagattat tggtgaggag tcaacttcaa ttgccaatag
    13561 aagatcaact ggtgactatg atttattatt caatcagaca tggggattag catatgatcc
    13621 acaaagtaca atttctgctt ttacttcccc atcttcttat ttacacacta ctaaaggaat
    13681 tgagaaagca gatgaacttt ataagaaaat tgacgatgtt atggtatcta tgaatgaaga
    13741 aacgcgtaga tcattgtacg ctgatattct aaaaattgtt catgatgaag cagtctttat
    13801 tccaatatcc aatggcagtg taactgtaat tgccccaaag aatttaaaag gaatttcgtt
    13861 taaacaaaca caattcaagt taccgtttga gaaaatgcac tttgaataga aattacaaat
    13921 aaaaagggag attatctccc tttttatttg taatgaacaa catctatttc aagttaattc
    13981 tatagatatt ccaatgatta atctagctat caatactatt ttttagaaag gagattatat
    14041 ataagatgtt gcattactaa aaagttatta atatctatac cattactttt agtcatctca
    14101 ttcctaactt ttattttaat taatctttct ccccaagatc cagctgaagt ggtattacac
    14161 gctcaaggtg ttccaaagat aacagatgaa ctaattattg aaacaaaaaa agaattagga
    14221 ctagatcagc cattcatcat gcaatattta cactggttaa tagcttgtct tcaattggag
    14281 tttggaaatt catatattac aggacaatcg gtttggtcat taatagggcc tgcatttttg
    14341 aatacattaa agctaacatt agtgtcatct gtttttgtca ttgttctttc aatatttcta
    14401 ggagtgctat gtgccatgag ggagggaagg ctatttgata aatcagtaag aggtgcctct
    14461 ttctttttaa catcagcacc atcctactgg ctggcatcca tgataatttg gtacttctct
    14521 atcaaattgg atttgttacc tacaagtggg atggattcat acaagagtta tatcctacct
    14581 gttaccataa ttacaataag ttatgccggt atctatttca gaattgtaag aagttctatg
    14641 ctaaataact taaatgaaga ctatgtatta tacggaagag catgtgggtt aaatgagcag
    14701 acaattactc tacagatttt aagaaattca ttacaggttt ccatttcagt attttgtatg
    14761 gcgataccta ttatattagg aagcacagta gtcatcgaaa atgtttttgc atggccagga
    14821 ttaggaagtc taagcgttaa gtctatcctg agtagggact tcccgattat tcaagcttat
    14881 gttcttttat tagcagtatc cttcgtagta tttaacacta tttctgacat cataaatgct
    14941 gctataaacc ctaagttaag gaatgattta taaatgagaa tattaaaaaa cttgagtaaa
    15001 gacaaattag ctattatgtc attaatagtt ataactttaa caatatttgt tgggatattc
    15061 gctcctatat ttgccccaca taaccctaaa gaagtaaata tggggcttcg atatgcatcc
    15121 tcatcttggg agtatttatt aggcaatgac catttaggaa gatgtattct ttctcgatta
    15181 atttacggaa ttcggcctag cgtgttatgg gtttcagttg ccttattact atctgttgtg
    15241 attggaactg tcatgggatt tctagctggc tattttcgag gaaaagtaga tgtagttatc
    15301 atgagaattt gcgatattat gctatctttt cctggttatg ttatgacttt agctattgtt
    15361 ggtattttag gggtggggct tgtaaatata ctaatttcct ttgttttcct taaatgggca
    15421 tggttcgctc gagttatcag aacttctgtt atgcaatata cagaactaga atatgtaaag
    15481 tttgctaagg cgtgtggcat tagtaatatt aggattattt ataaacacat agttcctgtt
    15541 accttatcag atgtgatagt cctttcaagc agctctgttg gttccatggt tttacaaata
    15601 tcaggtctct cgttcttagg attaggaata caagccccaa atgctgaatg ggggatgatg
    15661 ttgaatgaag ctaaagaagt tatgtttaca cgtccagaat taatgttagc tcctggttta
    15721 gccattatta ttgtagtgtc gtcttttaac tttctatctg atgctcttca agttgccctt
    15781 gatcctaagt tgatgagttc taagaataga ataaaaggaa gtctagccct ttctagacat
    15841 caaattggga aaaatgaggt ggcgaaataa atatatgaat atattagagg ttgaacatct
    15901 taaaatacaa gacattgaga acggcaaggt tattgttcat aatagttctt tcagtcttaa
    15961 acagggaagt tgtttagcga ttgttgggga aagtggaagt gggaaatctg taacttgtag
    16021 gtcaataatg aggttaaata aaccttcact ttctcaatct ggaactattc tgttcaaagg
    16081 tgaagaccta aatgctctta cagaaaaaga gatgagacag aaaagaggaa gaaatatttg
    16141 catgattctc caaaatggta tgactgcctt tgatccttct tgtgttgttg gagtacattt
    16201 gaaagaaact ctttttgagc attttggatg gaataagtta gagatagaaa gaaaaatgaa
    16261 gagcgctatg gagagtgtaa tgttgaaaaa tcctttggag attatgaata agtatcctca
    16321 tcagttatca gggggaatgc tacaacgtct tatgattgca ttatcaatag ctttagagcc
    16381 cgatattatc atagccgatg aacctacgac agcattagat acaatctcac aatttgaagt
    16441 tatagaacaa tttataaagc taagagaaaa aataggatgt tccatgattt ttatttcgca
    16501 tgatttaggt gttgtaaaga aagttggaga tgacatctta attatgaaag atggaataat
    16561 tgttgaaaga ggcagtattc aaaccacctt ctcacaggca caacatgaat acacaaatta
    16621 tttattatcc actaaacagg tactgagtaa taattttaaa aagataatgg ggatgaataa
    16681 taaatgttaa ttgtagaagg catagagaag gcttataaga ccggtgggtt attctctaag
    16741 gaaaaacaga aaatattaaa aaatgttagt tttgaatgta agagtggaga gtgtctaggg
    16801 gttattggag aaagtggaag tggaaaatca acattaggtc gtctattaat aggtattgaa
    16861 caacctgatg ctggaagagt tttgtttgaa ggaagaagtg tgaatgatag agtaattaga
    16921 ttgggcagta ttagtgccgt attccaagac tatacatctt ccattaatcc atttttcact
    16981 gtaaagcagg ctattataga acctataaaa attaaaaaaa gtaccaaaat agaaattgaa
    17041 aataggattg attacctttt gaaccaagtg gggttggcct cctcgtataa agagaaatat
    17101 cctcatgagt tatcaggagg acaaatacaa agggtatgta ttgctagggc tattgcaaca
    17161 gaaccaaaat gtattttatt agatgaagca attagttctt tagacgtatc cgtccaagtt
    17221 caaatactta aattattaaa agaattaaag gaaatctata acatgagcta tatcttcatt
    17281 actcacgata ttcaggctgc tgcttatatc tgtgacagaa tcatcatttt taaaaacgga
    17341 aaaattgaag aaactgtaga aacttcagat ttaaaaaatg ttcaatcagc atatgcaaga
    17401 aaattattac aaaaattaat aactttataa tatagtttat atcattcttg tctcagcata
    17461 aactgtggaa ttttatgaag atgttaaaat gaatgaggag gagaaaaagt tttgagtgga
    17521 gctatgtctt ggccttttct acgtttatat ggattaaccc ttctttactt tagtgcaaac
    17581 tctatactaa atgttattat tcctttacaa ggagaaacat taggagctag caatacaacc
    17641 attggtatca ttatgggtgc ttatttgttt accactatgt tttttcgacc atgggcagga
    17701 catattatac aaaaaaaagg gcctataaaa atattacgta taatccttgt cattaatgga
    17761 tttgccttaa tactctatac aatcactgga ctaggtggat ttttacttgc acgtatttta
    17821 caaggggtat caacagcttt tttctcaatg gcgttacaaa taggtattat tgatgccctt
    17881 ccagaggagg atcgttctca aggtatctcg ctttattcct tattttcaca tataccgggg
    17941 gttatcggcc ctatattagc attaggaatt tggcaagcaa acaatacatc ttactttatg
    18001 atagtgatga tatcgattac tatttttaca gggatttttg gttatagtgc taaagtggac
    18061 aagcaaggag atttaactga aataaatgat acgcatcaaa gagtaaatat gttcaaatca
    18121 tttggtgagt taataaaaaa tccatttttg ttcaaatgta gtgtgttaat gttagtagcc
    18181 tctattgtat ttggatctat tactaccttc ttacctctct acgctatgga attaaagaat
    18241 gggaacgctg gagtttatct aatgattcaa gcaggaactg ttgtgtttgc tcgttttact
    18301 ttaagaaaaa aaattccttc agatggtaaa tggcattctt cctttgtaat gggtacaatg
    18361 ctcctcctag cattagcagc gcaatgtgta agcttttcta taactggtgg agtaatgttt
    18421 ttctatatag gagcagtctt gatgggaata gctcaagcgc tcatatatcc taccttaact
    18481 acatatttga cttttgtttt accaaaagga aatcgtaata tattaattgg tctatttatt
    18541 gctatggcag atttaggggt atcactagga ggtgttatta tgggccccat agctgacatt
    18601 tcatcatact catttatgta tatgatttgt gctattttag gtggagcaat gattattttt
    18661 gcctatgatc aacgtaagat atttgttgag ggaaaataaa atctctattt cgttatctag
    18721 ttgatcagaa ttttttgcat tatattaagt aggttagaaa catacaataa tataaatttt
    18781 agtataaaaa gcttgtctct atagaggcga gctttcctgt ttaatggctg caggtctttc
    18841 ttttgctctc tttttattaa gtattacaga gggaggaatg actacaaata ttgaacaata
    18901 cttatttggt tccattgtaa ctattaggac acaacagctc tatattatgg caggagttac
    18961 attccttgtt ttactatatt tctctatttt taaaagacag ctttatttaa tgacattcga
    19021 ttagaataca gctgaaacaa gtggggtaaa tgtgagaatg ctttcgcttt tatttagcat
    19081 attagtaggt atagccattg ctgtaattat cccaacaagt ggagttttac ttgtatctgc
    19141 atgattagtt cttccagcaa cctttgccat tcggcttttt aaagggttta cagcggtttt
    19201 catggcctct atactcatcg ctcttttaag tattctgtct ggtcttactt cttcttataa
    19261 acagggaaca cctccaggcg caactattac tttattgtta gtagtatttt taattatagg
    19321 atttattgta cagaagatag ctttgttggc caaaagaaca cagcattgaa agttaaaaaa
    19381 gaggtgaaaa tagatatccc catgcggagt aaattgacga aacagcggtt tttatatatc
    19441 ttaaatagta atgattacga ttaataatca tgataatttt aataataaag ggaggtagca
    19501 ctgaatgatt ctatctgata aaggaattat aaaaagaata gaagaaaaag aactttatat
    19561 tgagccatta acaactaagc agattcaacc ggcttcctta gacttgagac tgggtggaaa
    19621 ctacctaaga attagagaaa atagagtcgg ggttctctcc ttagaaaagg aaatagaata
    19681 tgaaagcgta gagagtgatg aaattattat cccctctcat tcttttctat tagctacaac
    19741 catggagtat attaaacttc ctaataattt aacagctttt gtggaagggc ggagttctat
    19801 tggaagaatg ggcctattta ttcaaaatgc tggttgggta gatccgggtt ttgaaggaca
    19861 aattacactt gaattatata atgcaaatcg tctccccctt aaactagtta aaggatggag
    19921 aatttgtcag cttgtgtttg cagagatgga ccaatttcct aatcatcctt acgtaggaaa
    19981 atatcagggt cagataaaca caacaggtag tcgtagtttt ttagataaag acgatgaagg
    20041 attaagaaag gagaagtccc aatgaagttg cctgataaaa aagagagaca tcaattgttt
    20101 ggttctattg ctccaggtat gaagtataaa cctactagaa aagaagaaat ggtggattta
    20161 cagaacttga gtaaagattt tctttttact ataaaaaaag taggaattag taatgtgaaa
    20221 atccctgttc agttacaaag tagtttacca cctagacacc aaacaactat tgcaactttt
    20281 tcattaacct caaatctatc tcataaacaa aaaggaacaa atatgagtcg ctttttagaa
    20341 gtattagaga gatatcgtca gcaggggttt accttgaatt tctcaactct tcattgtttt
    20401 ttagaagaat tggcacaaaa gttagaacaa gaagccactt atttgcaagt ggaattcctt
    20461 tggttttatg atcgcatctc tccttcctcg aacctaaagg gtcttaacca tgccaatgtt
    20521 aagttagata tatcttatca taaagaaaaa ggatttaaag atgatgtgag tatgacatgc
    20581 ggaattacaa cgttatgccc ttgttcgaaa gaaattagtg aatatagtgc ccacaatcaa
    20641 aggggctatg tgaaaatgga tgtaaatata tctcctagtc atgtaaacga tgaattaaat
    20701 tggaaagaag acttattaga tgcagcagaa tctaatgcaa gtgcacgtct acatccttta
    20761 ttaaagagaa cagatgaaaa agtagtaaca gagcaagctt atgaaaaccc tcgttttgtt
    20821 gaagacatgg tacgactggt cggagcagat ttatatgagc ttaattggat taaaagtttt
    20881 acagtagaat gtagaaatga agagtctata catttacatg atgcatgtgc ttctatgtcc
    20941 gtacaaaaat aaaaagggat tttatggttg ctttataaag gggaacatag taccattaaa
    21001 tcgtaataat tacgatttgt agaggagttt tacatatgaa taagattcca gttacagtgt
    21061 taagtggata tttaggttct ggaaaaacaa ctttattaaa ttacatttta aagaatcgtc
    21121 aaggattaaa agtagctgtt attgtaaatg atatgagtga aattaacata gatgcagaac
    21181 ttgtaaaaca aggtggcgac ttatcaagaa cagaagagaa gcttgtagaa atgtctaatg
    21241 gatgcatttg ctgcacatta cgagaagatc tccttgtgga ggtagaaaag cttgctaaga
    21301 gaggaaacat tgactatatt gtcattgaat ccacaggtat tagtgaacct gtacctgtgg
    21361 ctcaaacctt ttcatatgtt gatgaagagt taggcataga tcttactaag ttttgcacac
    21421 tggatacaat ggttacggtt gtagatgcaa atcgtttctg gcaggatttt gagtcaggag
    21481 actctttact agatcgaaag gaagctgtag gagaaggaga tacaagagaa attgcagatt
    21541 tattaataga ccagattgaa ttctgtgatg tactcatttt aaacaaatgt gacctagtag
    21601 cagaggatga attaattaaa ttagaaagta tgctaagaac tttacaacct gatgctaaaa
    21661 ttattcgttc tattcaagca agagtggatc ctaaagagat tttaaataca aatcgctttg
    21721 attttgataa agcaagtgct tcagcaggat ggattaagga attaaatgac gggagtcatc
    21781 gtgaacatac tcctgaaacc gaggaatatg gaattggctc tttcgtatat agtagacgtg
    21841 ttccatttca tactcaacgt tttgaagact gggtacattc tatgccaaaa caaattgtac
    21901 gagcaaaggg aatttcttgg tgtgctagtc gaaatgattt agctctctta atgtctcagg
    21961 caggaccttc tgtaagcatt gaacctattt cttattgggt agcttcactg ccatctttac
    22021 agcaaaggag aatccttgcc gataatccgc aattagtggc tgagtgggat gaggagtatg
    22081 gagatcgtca cacaaaaata gtcttgattg gtgtagattt agataaagag gcgattatta
    22141 gagactta
//
