LOCUS       NZ_QLTT01000007        22568 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Lentzea atacamensis strain DSM 45479 Ga0215649_107, whole genome
            shotgun sequence.
ACCESSION   NZ_QLTT01000007
VERSION     NZ_QLTT01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea atacamensis
  ORGANISM  Lentzea atacamensis
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 445506)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 445506)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Expected Final Version            :: No
            Genome Coverage                   :: 111.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 11:04:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,181
            CDSs (total)                      :: 9,101
            Genes (coding)                    :: 8,972
            CDSs (with protein)               :: 8,972
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 6 (5S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 27 of 129
            Pseudo Genes (incomplete)         :: 107 of 129
            Pseudo Genes (internal stop)      :: 5 of 129
            Pseudo Genes (multiple problems)  :: 10 of 129
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:43:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 133405
            Orig. end                         :: 155973
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QLTT01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22568
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22568
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22568
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12568](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12568)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            155..373
                     /locus_tag="C8D87_RS48055"
     CDS             155..373
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039414.3"
                     /locus_tag="C8D87_RS48055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6343 family protein"
                     /protein_id="WP_229813372.1"
                     /transl_table=11
                     /translation="MSDYLPPPAPPRSALTLRLWLAGFGLVFNSVAGWLALRADLVWLA
                     IVLLLLAVVCVVDFGWVLHRKRRGDPG"
     misc_feature    299..301
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            469..1092
                     /locus_tag="C8D87_RS29460"
                     /old_locus_tag="C8D87_107152"
     CDS             469..1092
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098998.1"
                     /locus_tag="C8D87_RS29460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107152"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_112229144.1"
                     /transl_table=11
                     /translation="MRRQPVQQRGAATVSAILEACASLLNEYDYDDITTARIVDVAGVP
                     IGSFYQYFPDKRSVVHALALRGMETYLREVEQLFAADLIADTWREAMNQIVSVYLRMLT
                     DLPGFGRVRFSDMLDSHRLDSSVDQYELMAERLAEMFVDRFGVHGEAPVMLTFRIAVQT
                     ADALFKLAERVDADDHAYVVGTANELLAGMLAPIFDQQPAPQSP"
     gene            complement(1080..2420)
                     /locus_tag="C8D87_RS29465"
                     /old_locus_tag="C8D87_107153"
     CDS             complement(1080..2420)
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800157.1"
                     /locus_tag="C8D87_RS29465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107153"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_112229332.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.1e-40, bitscore:
                     134.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFDVIVIGGGPVGENVAWRTAAGGLSTAMIEKELVGGECSYWAC
                     MPSKALLRPGHALAAARRVQGVNAGSLDPAAVLARRTGFTSNWDDSGQVKWAESENITV
                     IRGDGEVTGEREVTVGGDVHRARQAVVVCTGSVPKMPPLEGLADAPVWTSREATSAREV
                     PDSLVVLGGGVVGVEMAQAWARLGSKVTLVVSGDRPLPRMEEFVGPLVVEGLQEDGVEV
                     LLNARASAIAPGALTLQDGRVVHGSEILVATGRVPATKDGKPLTIDDSGLVSGVDGRWL
                     YAAGDVTGRALLTHQGKYQARAVGTAILERSRGFEPKQWSAGQAWADHVAVPQVVFTDP
                     EVAFVGHTAEEARKAGRDVRVVDLDIAVAGSSLHADGYHGRTRMVVDERTRTLVGVTFV
                     GQDVSELLHSATVAIVGEVTVDRLWHAVPSYPTISEVWLRLLEAYGL"
     gene            complement(2503..2862)
                     /locus_tag="C8D87_RS29470"
                     /old_locus_tag="C8D87_107154"
     CDS             complement(2503..2862)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681008.1"
                     /locus_tag="C8D87_RS29470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107154"
                     /product="VOC family protein"
                     /protein_id="WP_109641262.1"
                     /transl_table=11
                     /translation="MVGQLRSVVLDCPDPSELASFYEKLLGAQRLAGGDDTWVVIVANG
                     TRLAFQRSDDYRPPTFPDPHGSQQFHLDVLVEDVEKAEPRVLELGARLLQKDNDDTFRV
                     YADPVGHPFCLVWLS"
     gene            complement(2875..4110)
                     /locus_tag="C8D87_RS29475"
                     /old_locus_tag="C8D87_107155"
     CDS             complement(2875..4110)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099001.1"
                     /locus_tag="C8D87_RS29475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107155"
                     /product="hypothetical protein"
                     /protein_id="WP_109641263.1"
                     /transl_table=11
                     /translation="MRLIRLGAEPSAVGADVRAALTACGAGTEVLGGVALAGVQPPGCP
                     VPLDAIVVLPKGVLVIVGVDLPDPAVKLEAPLGGQWKIDGWPLVSQDGTANPATEAVAA
                     ATAVAQRIQAMRAEPLPVSTVVAVGPFVSQVVQPTSDLNRGVRVLHPKPSTLLSAAREL
                     ATSSVPCTADHAMKLLAILQTTGTPPDARTLLSEGFSDAVSPDLAAASTMLIPKIQAKP
                     ALPRKRLHQAVRWQYLALGGLVAALLFVWLLVALPGDDQPADATPAPSATSPTTVVVDG
                     TTFVPKDVKSDKDCQAQAFGDAKAWLIANECSALLRATYETSVQGKQATVLVADLDLMD
                     APSATAFHKVVTAPGSGGVHGMDGKPLENAAFASGAKGSHVQLAFVVWSGGAGDQSLDA
                     IAKQALRLPTTR"
     misc_feature    complement(4185..4200)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            4254..5597
                     /locus_tag="C8D87_RS29480"
                     /old_locus_tag="C8D87_107156"
     CDS             4254..5597
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017984125.1"
                     /locus_tag="C8D87_RS29480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107156"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_109641264.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3e-43, bitscore:
                     143.0, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKRAALLAVVLVAASTPVAAALPTSTVYVHGADIAAAEQAVAAA
                     GLQKITSFRKIGVVAARGDSARISSARAKAGVTRVEVQKPIKFLGSTSHTATRGLDARN
                     SLGLTGAGVSVAVIDSGVDPTHPSFSGGKIVRNLKSLCLDGATDSSCIVPVPNFVDTDT
                     TSLGGHGTHVTGIAIGNDVQLTGGPVVRGAAPGAKGVVISTGAAILILGADAALNWVLE
                     NHKAPCGAGVPASTCPPIKVINNSYGPSGGGAFDPESVTVKLQRQLVAEGVVVVWANGN
                     DGGDGSANLSNPPGTDPTPGVISVASYNDLETGTRDGALSSFSSRGLATNPATWPDISA
                     PGENITSSCRLYLPICATGLAPQNGPGLLDLGTFNTISGTSMAAPHIAGIVAQLFQAKP
                     SATPADIERALKSSAHKYGTGYQPVGPYTSSFDKGTGLVDVVAAVNVL"
     gene            5798..6301
                     /locus_tag="C8D87_RS29485"
                     /old_locus_tag="C8D87_107157"
     CDS             5798..6301
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009074684.1"
                     /locus_tag="C8D87_RS29485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107157"
                     /product="DUF3145 domain-containing protein"
                     /protein_id="WP_109641265.1"
                     /transl_table=11
                     /translation="MSTRGSTSGVVYVHSSPSAVCPHVEWAISGTLGERVDLRWAAQPA
                     APGQLRAECAWTAEAGTGAKLVAALRAWPMLRFEVTEEPSPGQDGERFCFAPVLGLWHA
                     RTSANGDIVVNEDQLRALAARSRGGESFAHGVDELLGAAWDDALEPFRRAGDGAPVTWL
                     HRVG"
     gene            complement(6318..8036)
                     /locus_tag="C8D87_RS29490"
                     /old_locus_tag="C8D87_107158"
     CDS             complement(6318..8036)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099004.1"
                     /locus_tag="C8D87_RS29490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107158"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_109641266.1"
                     /transl_table=11
                     /translation="MRFYLSTLAGHRRGVLILLGWSVLEGVPAFFGGRLVGTAVDKGFA
                     AGDPRSGVLWLLAFAALAVAGALGQRQVFARLGAVVEPMRDALVTRIVQGVLDDPTHRR
                     TPDASAVAMITRHVEVVRDATAGVLVQARALLVTTVAALIGLATTAAALIWLVVLPIVA
                     SLVLFALLLPSLAKRQRDAVIADERTAEASGAVLTGLRDVAACKAAEEAFADIATEVNR
                     QAKATVTVAWANSLRATVIALGGFTPVVLLVAFAPPLVASGQLTTGAVLAAVVYLTNNV
                     NPALHGLARTTSTVVMRLMVALKRLQEVAPRTNKKIGTEVPSNGEVVLRDVTFGWSQDA
                     EPVLRDLSLTLRPGDHLAVVGPSGIGKSTMASLLTGLMPPDLGRVLFGGAPVDLVVPEV
                     RHHAIALIPQETYLFTGTVRENLTLLAPWATDDELLEAVKKVGAKPILDRLGGLNATLG
                     HAGEGLSAGEAQLLALARVHVTSASIVILDEATSHLDPAAEARVERVFAQRDGILVVIA
                     HRLSSALRANRVLVMDGGKPLLGTHEDLLRTSPLYGQLMLAWDPTHHEETPLPKR"
     gene            complement(8036..9655)
                     /locus_tag="C8D87_RS29495"
                     /old_locus_tag="C8D87_107159"
     CDS             complement(8036..9655)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005163360.1"
                     /locus_tag="C8D87_RS29495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107159"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_109641267.1"
                     /transl_table=11
                     /translation="MAKPGDALLFSVVRRDHRPWLLLLNAAVATTGGLLIPSALADAVD
                     MALGGTFVLFTLLWLLGMAATEIIGDAIGIVLAASITSRATAWLRHRLSRHLLALGHPS
                     PFAAGDAVSRVTGDCGNAGGIVVTLISLAIAAASSVGSVVALALMDWRLAAVFVVSVPL
                     AMFLVRTHMQLTADDVLAYQEVSGDVSARLLDAVSGKRTIAAAGIAGREADRVLQPLPR
                     LAAAGAGMWRTQAKMMWRAGLLLPAVEVVVLITAGFGVMEGRLSPGDVLAALGYAALGM
                     GIVGQIPQLTALERTRASASRIAEVLDTPPPDRAAPVAPESGAIELRGAGVTGVLHDVN
                     LTIPAGAFTAVVGSSGAGKSTLAAVLGGLSAVDSGEVLRDGEVGYAFERPALLGRTIGR
                     SIGYGTVAGEAEVRDAAVAAQVHDVLIRLPQGYDTPVAEAPLSGGEVQRIGLARAIVRD
                     PALLVLDDATASLDTVTEAKVDAALTTALPGRTRVVVTHRAATAARADLVVWLENGRVR
                     GTGTHQELWENEDYRAVFTGGE"
     gene            complement(9799..9960)
                     /locus_tag="C8D87_RS29500"
                     /old_locus_tag="C8D87_107160"
     CDS             complement(9799..9960)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800163.1"
                     /locus_tag="C8D87_RS29500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107160"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_109641268.1"
                     /transl_table=11
                     /translation="MGFILDMQDLETPETTSVMASGGSGGGGGGSTTASNASLLLPCSH
                     STVSLLAC"
     CDS_motif       complement(9898..9960)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGFILDMQDLETPETTSVMAS"
                     /locus_tag="C8D87_RS29500_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9799..9897)
                     /prepeptide="core"
                     /locus_tag="C8D87_RS29500_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="10.20"
                     /molecular_weight="2639.9"
                     /monoisotopic_mass="2638.3"
                     /core_sequence="GGSGGGGGGSTTASNASLLLPCSHSTVSLLAC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGFILDMQDLETPETTSVMAS"
                     /leader_location="[9897:9960](-)"
                     /alternative_weights="2657.9"
                     /alternative_weights="2675.9"
                     /alternative_weights="2693.9"
                     /alternative_weights="2712.0"
                     /alternative_weights="2730.0"
                     /alternative_weights="2748.0"
                     /alternative_weights="2766.0"
                     /alternative_weights="2784.0"
     gene            complement(10001..12568)
                     /gene="lanKC"
                     /locus_tag="C8D87_RS29505"
                     /old_locus_tag="C8D87_107161"
     CDS             complement(10001..12568)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009949110.1"
                     /locus_tag="C8D87_RS29505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107161"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_109641269.1"
                     /sec_met_domain="micKC (E-value: 0.0, bitscore: 1072.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 5.4e-15, bitscore: 50.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 2.9e-07, bitscore: 25.5,
                     seeds: 156, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.9e-12, bitscore:
                     40.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLRYEAFCFADRRFYDLQSSTESDLPGDDFSRDLPELPAGWVQA
                     ERNVWRHLHPQGVTLPKQGWKIHVSAGLDNASRVLKATFDYCVERRIPFKYLPTISIVL
                     ARNSKYAPREGSGKLITIYPAGTEQLQSILTELGATLQGEHGAYILSDLRYGKGPLYVR
                     YGGFSEQWLEVDGQQVLAIEGPDGTLIPDKRKPVFSVPEWVELPEFLAPHLAERNAGDP
                     AKFPYQIKSSLHFSNGGGVYLATRKSDGKEVVLKEARPHAGLDREGRDAVARLELEHTI
                     LTKLEKVQGVPEVYDRFTEWEHLFVAMEFMPGRSLGQWLGHNYPLTHKDTTDEQLAEYR
                     ERALKLVTKVEDLMARVHERGVVFGDLHTLNILVDDDDEVSLIDFELSSTIEDVKRPTL
                     GAPGFQAPSDREGFEIDEYPLAALKLWIFLPLNAVLELSPAKLKQHVHVIQQRFGLGDE
                     YCRSIVDVLTPRVDPPEEPAFTAFDDPEPDWTVVRKSIATAILHSATPQRQDRLFPGDI
                     EQFEVGGTCFGYGAAGVLHALDVSGEGRYPEHEDWLIKAVRKDPPKQPGFFVGAHGIAH
                     VLENFGHHDLATELVEGYTQLVATTRDHGLSAGLSGIGLNLLHFADVREDHGFAARAEE
                     LAERLAEQLAGAPGPGDKAKAGLLHGWSGPALFFLRMFERTGERRWLRLSEQALERDLA
                     ETMVALDGSLQVRDGTFRSLPYVGIGGAGIALVLTEFAAVAPERPCVEKLPELLTGCTG
                     EFVIQPAFALGRAGLMATLAQAAAHKPDERLDRAIQQHLRALGWHAVRYGGGLAFPGVQ
                     LRRLSMDLNTGGAGVLLAIASTVDGRPPLPFLGRTQAPVLANR"
     misc_feature    12619..12635
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.25"
                     /tool="antismash"
     misc_feature    12709..12722
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 21.12"
                     /tool="antismash"
     misc_feature    complement(12794..12806)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.22"
                     /tool="antismash"
     misc_feature    complement(13051..13063)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.24"
                     /tool="antismash"
     misc_feature    13095..13104
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     misc_feature    complement(13096..13112)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            13353..13919
                     /locus_tag="C8D87_RS29510"
                     /old_locus_tag="C8D87_107162"
     CDS             13353..13919
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D87_RS29510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D87_107162"
                     /product="hypothetical protein"
                     /protein_id="WP_146231848.1"
                     /transl_table=11
                     /translation="MASRWLVPAVVVITGASVAAGMVGRTVYSRPAEAKGEPVVPSSSV
                     SGAALPGGSEVRLSPDSFTHPDRTSVQKVLQKYFDAINERDFAGWRGVVSARRASQAVE
                     KTWLAAYETTQDGGVVVQRVESDVVARRLRVLISFVSTQDVSKAPVAMPEPCIRWRVVY
                     VMVWEGGELKVDEAPENRTPQMEKC"
     gene            complement(14246..15481)
                     /gene="fabF"
                     /locus_tag="C8D87_RS29515"
                     /old_locus_tag="C8D87_107163"
     CDS             complement(14246..15481)
                     /EC_number="2.3.1.179"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (8-406). E-value:
                     2.6e-48. Score: 156.9. Matches aSDomain:
                     nrpspksdomains_C8D87_RS29515_PKS_KS.1"
                     /codon_start=1
                     /gene="fabF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FabF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017984122.1"
                     /locus_tag="C8D87_RS29515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107163"
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="WP_109641271.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.3e-60, bitscore:
                     199.9, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="FabF (E-value: 2e-173, bitscore: 571.7,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSDIDVVITGLGATTPLGGDVTSTWDALLAGKSGVRPLTHDWVE
                     KYELPVKIASQLVVDPTEVLPRVEARRLDRSEQVAIVASRQAWQDAGHSDDTVDRQRLA
                     VIIGTGIGGAITLLAQDDLLEQQGLRKVSPLTVPMLMPNGPAAHVGLELKAQAGVHAPV
                     SACASGAEAIAWAYRMIKAGEADVVVAGGAEACITAIPVAGFSQARTMSTRNDEPEKAS
                     RPFDTARDGFVLGEGAGVMVLERREFAEARGAKIYGRLAGIGTSADGYHITAPDPEGVG
                     QSRAIAASLRSGGIDPSDVGHVNCHATSTPVGDVAETVAIRKAIGDHPVLTAPKGALGH
                     LLGAAGAVEAIVTVLSIRDGVVPQTLNLENLDPAVTLDVVAGEPRKIKLDAAVNDSFGF
                     GGHNVALAFTPA"
     aSDomain        complement(14264..15457)
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D87_RS29515_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.60E-48"
                     /label="C8D87_RS29515_PKS_KS.1"
                     /locus_tag="C8D87_RS29515"
                     /protein_end="406"
                     /protein_start="8"
                     /score="156.9"
                     /tool="antismash"
                     /translation="ITGLGATTPLGGDVTSTWDALLAGKSGVRPLTHDWVEKYELPVKI
                     ASQLVVDPTEVLPRVEARRLDRSEQVAIVASRQAWQDAGHSDDTVDRQRLAVIIGTGIG
                     GAITLLAQDDLLEQQGLRKVSPLTVPMLMPNGPAAHVGLELKAQAGVHAPVSACASGAE
                     AIAWAYRMIKAGEADVVVAGGAEACITAIPVAGFSQARTMSTRNDEPEKASRPFDTARD
                     GFVLGEGAGVMVLERREFAEARGAKIYGRLAGIGTSADGYHITAPDPEGVGQSRAIAAS
                     LRSGGIDPSDVGHVNCHATSTPVGDVAETVAIRKAIGDHPVLTAPKGALGHLLGAAGAV
                     EAIVTVLSIRDGVVPQTLNLENLDPAVTLDVVAGEPRKIKLDAAVNDSFGFGGHNVAL"
     gene            complement(15478..15714)
                     /locus_tag="C8D87_RS29520"
                     /old_locus_tag="C8D87_107164"
     CDS             complement(15478..15714)
                     /NRPS_PKS="Domain: PP-binding (8-74). E-value: 4.7e-19.
                     Score: 60.5. Matches aSDomain:
                     nrpspksdomains_C8D87_RS29520_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657583.1"
                     /locus_tag="C8D87_RS29520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107164"
                     /product="acyl carrier protein"
                     /protein_id="WP_030465146.1"
                     /sec_met_domain="PP-binding (E-value: 1.8e-18, bitscore:
                     61.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding_2 (E-value: 0.00066, bitscore:
                     14.8, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNVLSGLAEIVEEVAGVAADDVTAEKSFVDDLDIDSLSMVEIA
                     VQAEDKFGVKIPDDELANLKTVGDAVNYITSNK"
     aSDomain        complement(15493..15690)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D87_RS29520_PP-binding.1"
                     /evalue="4.70E-19"
                     /label="C8D87_RS29520_PP-binding.1"
                     /locus_tag="C8D87_RS29520"
                     /protein_end="74"
                     /protein_start="8"
                     /score="60.5"
                     /tool="antismash"
                     /translation="LAEIVEEVAGVAADDVTAEKSFVDDLDIDSLSMVEIAVQAEDKFG
                     VKIPDDELANLKTVGDAVNYI"
     gene            complement(15758..16735)
                     /locus_tag="C8D87_RS29525"
                     /old_locus_tag="C8D87_107165"
     CDS             complement(15758..16735)
                     /EC_number="2.3.1.180"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019819235.1"
                     /locus_tag="C8D87_RS29525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107165"
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="WP_109641272.1"
                     /sec_met_domain="fabH (E-value: 5e-103, bitscore: 339.4,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTFQAPRTSAGSRIIGLGSYQPETVVSNHDFAARMDTSDEWIRD
                     RVGIVNRRFAAKDEGVVDMAVIAGGKAIEDAGIDPADIGAVIVATCTMPSTIPNAAAQI
                     ADRLGVKAAPAFDLNAACAGFCYAVATGADLVRAGTARNVLVIGAEKLTDWTDQDDRST
                     AIIFADGAGAVVIGASEENQIGPVAWGSAGDLAETITITDRDSFIHQEGQSVFRWATTQ
                     IAPVAIRAAELAGVELSEVDVFAPHQANLRIIEAIAKRLRAKGAREDLKVARDIVESGN
                     TSSASIPMALDHMRAAGEISSGDVVLMVGFGAGLSYAGQVVRCP"
     gene            complement(16732..17661)
                     /locus_tag="C8D87_RS29530"
                     /old_locus_tag="C8D87_107166"
     CDS             complement(16732..17661)
                     /EC_number="2.3.1.39"
                     /GO_function="GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_AT (6-285). E-value: 2.1e-43. Score:
                     140.7. Matches aSDomain:
                     nrpspksdomains_C8D87_RS29530_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800169.1"
                     /locus_tag="C8D87_RS29530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107166"
                     /product="ACP S-malonyltransferase"
                     /protein_id="WP_112229145.1"
                     /sec_met_domain="PKS_AT (E-value: 1.7e-42, bitscore: 140.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIALLAPGQGSQTPGMLAPWLELEGTEKQVRTWSEITGLDLVRLG
                     TTAEAEEIVDTAITQPLVVALALLAFGELRRRVELPAGVIVAGHSVGELAAASIAGVIS
                     ADDAVALAAVRGAAMAEACALEPTGMAAVLGGDEQEVLARLDELGLVPANRNGAGQIVA
                     AGPRPALDELAETPPGTAKVRKLAVAGAFHTKYMAPAEDAVRARAAEVTTHDPLMPLLS
                     NKDGQAVTEGTEVLRRLVSQVTSPVRWDVCQATLVGKGVSGSVELPPAGALTGLAKRAM
                     KGTATLALKTPDQLEKVAELFDTVGATQ"
     aSDomain        complement(16807..17643)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D87_RS29530_PKS_AT.1"
                     /evalue="2.10E-43"
                     /label="C8D87_RS29530_PKS_AT.1"
                     /locus_tag="C8D87_RS29530"
                     /protein_end="285"
                     /protein_start="6"
                     /score="140.7"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="PGQGSQTPGMLAPWLELEGTEKQVRTWSEITGLDLVRLGTTAEAE
                     EIVDTAITQPLVVALALLAFGELRRRVELPAGVIVAGHSVGELAAASIAGVISADDAVA
                     LAAVRGAAMAEACALEPTGMAAVLGGDEQEVLARLDELGLVPANRNGAGQIVAAGPRPA
                     LDELAETPPGTAKVRKLAVAGAFHTKYMAPAEDAVRARAAEVTTHDPLMPLLSNKDGQA
                     VTEGTEVLRRLVSQVTSPVRWDVCQATLVGKGVSGSVELPPAGALTGLAKRAMKGTA"
     CDS_motif       complement(17302..17409)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D87_RS29530_0002"
                     /evalue="2.00E-13"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="C8D87_RS29530"
                     /protein_end="120"
                     /protein_start="84"
                     /score="42.3"
                     /tool="antismash"
                     /translation="IVAGHSVGELAAASIAGVISADDAVALAAVRGAAMA"
     CDS_motif       complement(17611..17643)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D87_RS29530_0001"
                     /evalue="3.50E-03"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="C8D87_RS29530"
                     /protein_end="17"
                     /protein_start="6"
                     /score="10.5"
                     /tool="antismash"
                     /translation="PGQGSQTPGML"
     misc_feature    complement(17730..17746)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.9"
                     /tool="antismash"
     misc_feature    17831..17846
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     gene            complement(17856..19058)
                     /locus_tag="C8D87_RS29535"
                     /old_locus_tag="C8D87_107167"
     CDS             complement(17856..19058)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153085.1"
                     /locus_tag="C8D87_RS29535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107167"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_109641274.1"
                     /transl_table=11
                     /translation="MTKAAEAKEEHPPTLSARTMRKIERASGALATASVAEMEQRLPWF
                     ARMPADQRASVLLLIQNGVAGFVEWLHDRQQAIRLTADAFRSAPKDISRWVSLRQTVEL
                     VRIALEHFEEQMPAMAGTEAERALLMEGVLRYGREIAFSAATSYAAAAEARGAWDARLE
                     ALVVDGVVRGDPEESLLSRAAALGWDPALEATVLVGNPGGEDPPAIIYSVRSKAARAGR
                     PVLLSVQGSRLVVVLGGPTETGEDVLGRIAEGFGEGPVVAGPTVASLAEAHRSASDALS
                     GLRAVVGWPAAPRPVRSLDLLPERALAGDPEAEWQLVDRVARPLEDAGGALLETVDAFL
                     EVGGVLETCAKRLFVHPNTVRYRLRRVQEMTGRNAHDARDALVLRVALSVGRLARARGL
                     W"
     gene            19179..20735
                     /locus_tag="C8D87_RS29540"
                     /old_locus_tag="C8D87_107168"
     CDS             19179..20735
                     /NRPS_PKS="Domain: Abhydrolase_1 (87-276). E-value: 5e-19.
                     Score: 60.8. Matches aSDomain:
                     nrpspksdomains_C8D87_RS29540_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099013.1"
                     /locus_tag="C8D87_RS29540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107168"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_233442354.1"
                     /sec_met_domain="PF00561 (E-value: 3.3e-24, bitscore: 80.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRFPAFVLGMVALTATGVTASADPPDPLAEYHAQPVKWAACSGK
                     LSGLECATLVAPLDHAKPAGDRINLTISRRKAAAQDRRRGVLFTNPGGPGGSGLSLPLF
                     LAKSELAQVYDVIGIDPRGVGGSTALNCRAAPAIAAPDSRPADGEFGKWAAEAREAEES
                     CQRSAGGIRQFISTANTARDMDIVRAVLGEAKINYLGYSYGTYLGAVYGTLFPNRLDRS
                     VLDSAVHPEWIWHEQFRQQAVAYRRSVEAWAAWVGERNQKFALGKSRDEVLAEVEKVAA
                     KLHTAPIGEHDRSSFDGAVGVGSRYRPLWSDLASIVIKLRSGEKPENTEGAKAGQVLAK
                     TGLRELRSGVFDTVTCESDWPTDLHVYYEDMRTFRERYPFGFGIVRAAPMTCTFRSFTP
                     PEQPVRIGRSGYPVGVVVQSEGDTQTQYASGPAMAARLGHNLITVIDEGKHGIYNGGNK
                     CVDEKVNRYLIDGALPGSSSECTGDPRPDVPKDGQGGAAPALSPNRIQGYLEGRGLSAR
                     P"
     aSDomain        19440..20006
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D87_RS29540_Abhydrolase_1.1"
                     /evalue="5.00E-19"
                     /label="C8D87_RS29540_Abhydrolase_1.1"
                     /locus_tag="C8D87_RS29540"
                     /protein_end="276"
                     /protein_start="87"
                     /score="60.8"
                     /tool="antismash"
                     /translation="FTNPGGPGGSGLSLPLFLAKSELAQVYDVIGIDPRGVGGSTALNC
                     RAAPAIAAPDSRPADGEFGKWAAEAREAEESCQRSAGGIRQFISTANTARDMDIVRAVL
                     GEAKINYLGYSYGTYLGAVYGTLFPNRLDRSVLDSAVHPEWIWHEQFRQQAVAYRRSVE
                     AWAAWVGERNQKFALGKSRDEVLAEV"
     misc_feature    complement(20753..20766)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            20942..21712
                     /locus_tag="C8D87_RS29545"
                     /old_locus_tag="C8D87_107169"
     CDS             20942..21712
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004559013.1"
                     /locus_tag="C8D87_RS29545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_107169"
                     /product="hypothetical protein"
                     /protein_id="WP_112229147.1"
                     /transl_table=11
                     /translation="MGSQITEGLGQAWAMIATFVPKLLGFLLVLVIGWFIAKALAKGVQ
                     FLLKRLGFEKLVDKSGLNSAMRQSSMDATGLIAKIVYYFVLLIALQLAFGVFGASNPVS
                     TLLNEVIAYLPRIVVAMVLVIVASAIGTALKGLVTGALGQRSYTRIMGNITYGFVMALG
                     IIAALNQLGIAISVTMPVLIAVLATVAGVIVIGVGGGLVRPMQQRWEGWLNRMQDEAQA
                     MSPMPRASQEMPATVGVRPGDAPTPPAGTPMPEK"
     misc_feature    complement(22173..22187)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
ORIGIN
        1 atgcgagccg gcatcacagc cgccgtgctg accgctgtcg tccccctcat cgcccctggt
       61 ctggccgtca cgcgtctcgt taggccctat gtgacgaaac cccctcggca gctcaggcgg
      121 gttgaggcgc cgctgctgag ggaaaccggg tgaggtgagc gactacctgc cacccccggc
      181 gcctccgcgc agtgctctga cactgcggtt gtggctcgcc ggattcggcc tggtcttcaa
      241 ctcggtcgcg gggtggctgg cactccgagc tgacctcgtc tggctcgcaa tcgtgctttt
      301 actactcgcc gttgtctgcg ttgtcgactt cggttgggta cttcatcgca aacgccgcgg
      361 agatccaggc tgaaacctgt cgggaacctg tgcttgggct taacgggtcg tatggataaa
      421 gatgttcgag tgcatgaaga cccggctagg ggcaggttag ccagggtgat gcgtcgacag
      481 ccggtgcaac agcgtggcgc ggctaccgtc tccgcgatcc tggaagcttg tgcgagcctg
      541 ctgaacgaat acgactacga cgacatcacc acggcgcgca tcgtcgatgt ggccggagtg
      601 cccattggtt ccttctatca gtacttcccg gacaaacgat ccgttgtcca cgcactcgca
      661 ctgcgcggta tggagacgta tctgcgcgag gtcgagcagc tgttcgccgc cgacctgatc
      721 gcggacacgt ggcgtgaggc gatgaaccag atcgtcagcg tctacctgcg catgctgacc
      781 gacctgcccg gcttcggcag ggtgcggttc agcgacatgc tggacagcca ccggctcgac
      841 tccagcgtcg accagtacga actgatggcc gagcggctgg cggagatgtt cgtcgaccgg
      901 ttcggcgtgc acggcgaagc cccggtgatg ctgaccttcc ggatcgccgt gcagaccgcg
      961 gacgcgttgt tcaagctcgc cgaacgcgtc gacgccgacg accacgcgta cgtggtcggc
     1021 acggcgaacg agctgctggc cggcatgctg gcgccgatct tcgaccagca gcccgcacct
     1081 cagagcccgt aggcctccag cagccgcagc cagacctcgc tgatcgtcgg gtacgagggc
     1141 accgcgtgcc acaagcggtc cacggtgact tccccgacga tcgcgacggt ggccgagtgc
     1201 agcagctcgg agacgtcctg gccgacgaac gtgacaccga ccagcgtccg cgtgcgctcg
     1261 tccacgacca tccgcgtcct gccgtggtac ccgtccgcgt gcagcgacga cccggcgacc
     1321 gcgatgtcga ggtcgaccac cctgacgtcc cggccggcct tgcgcgcttc ctccgcggtg
     1381 tgaccgacga acgccacctc ggggtcggtg aacaccacct gcggcaccgc cacgtggtcc
     1441 gcccaggcct gtcccgccga ccactgcttc ggctcgaacc cgcgcgaccg ctccaggatc
     1501 gccgtgccga ccgcccgggc ctggtacttg ccctggtgcg tcagcagcgc gcgcccggtg
     1561 acatcacccg ccgcgtagag ccagcgtccg tccacaccgg acaccagtcc ggagtcgtcg
     1621 atggtcagag gcttgccgtc cttcgtcgcc ggcacccgcc ctgtcgccac gaggatctcg
     1681 gagccgtgca cgaccctgcc gtcctgcaac gtcagcgcac ccggcgcgat cgccgacgcg
     1741 cgggcgttga gcagcacctc gacgccgtcc tcctgcaggc cctcgacgac gagcggcccg
     1801 acgaactcct ccatccgcgg caacggccga tcgccggaca ccaccagcgt caccttcgac
     1861 ccgagccgcg cccacgcctg cgccatctcg acgccgacga cgccaccgcc cagcaccacc
     1921 agggaatccg gaacctcgcg cgctgacgtg gcttctcgcg acgtccacac aggagcgtcg
     1981 gcgaggcctt ccagcggcgg catcttcggg acgctgccgg tgcacaccac gacggcctga
     2041 cgcgcgcggt ggacgtctcc tcccaccgtc acctcgcgtt cgccggtgac ctcaccgtcg
     2101 ccgcggatga ccgtgatgtt ctccgactcg gcccacttga cctgaccgga gtcgtcccag
     2161 ttggacgtga acccggtgcg cctggccagc accgcggccg ggtccagcga cccggcgttc
     2221 acaccctgca cgcgccgggc ggccgcgagc gcgtgaccgg gccggagcaa cgccttcgaa
     2281 ggcatgcacg cccagtacga gcactcgccg ccgaccagct ccttctcgat catggcggtg
     2341 gacagcccac ccgcggccgt ccgccacgcc acgttctcac ctacggggcc accaccgatg
     2401 acgatgacgt cgaagtccat gcggcccaca ctaggcccga actagtgccg tgacagccaa
     2461 ccttcaccgc gtcttcgacg ctcagcgggc cacctcgcgg cactaggaca gccacacgag
     2521 gcagaacgga tgccccacgg ggtccgcgta gacccggaac gtgtcgtcgt tgtccttctg
     2581 cagcaaccgg gcccccagct ccagcacccg cggttcggcc ttctcgacgt cctcgaccag
     2641 cacgtcgagg tggaactgct gcgagccgtg cggatcgggg aacgtcggcg gccggtagtc
     2701 gtcgctgcgc tggaacgcga ggcgcgtccc gttcgcgacg atcaccaccc aggtgtcgtc
     2761 accgccggcg aggcgttggg cgccgagcag cttctcgtag aacgacgcca gctcggaggg
     2821 atcaggacag tccagaacca cagaacgaag ttgtccgacc atgccctcca ccttctaccg
     2881 ggtggtgggc agccgcaacg cctgctttgc gatcgcatcg agcgactggt cgcccgcgcc
     2941 accggaccac accacgaacg ccagctgcac gtggctgccc ttggccccgc tcgcgaacgc
     3001 cgcgttctcc agcggtttgc cgtccatccc gtgcacgccg cccgaccccg gcgcggtgac
     3061 gaccttgtgg aacgcggtcg cgctcggcgc gtccatcagg tcgaggtcgg ccacgagcac
     3121 cgtcgcctgc ttgccctgca ccgacgtctc gtaggtggcg cgcagcagcg ccgagcactc
     3181 gttcgcgatc agccacgcct tcgcgtcgcc gaacgcctgc gcctggcagt ccttgtcgct
     3241 cttcacgtcc ttgggcacga acgtcgtgcc gtccacgacc accgtcgtcg gcgacgtcgc
     3301 cgacggtgcc ggcgtcgcgt cggccggctg gtcgtcaccg ggcaacgcca ccagcaacca
     3361 gacgaagagg agcgcggcga ccagtccgcc cagcgcgagg tactgccagc gaaccgcctg
     3421 gtgcaaacgc ttgcgcggca gtgcgggctt ggcctggatc ttcgggatca gcatcgtgct
     3481 ggcggccgcg aggtcggggg agacggcgtc gctgaagccc tcgctgagca acgtccgcgc
     3541 gtccggcggc gtgccggtgg tctgaagaat cgcgaggagc ttcatggcgt ggtcggccgt
     3601 gcacggcacc gacgacgtcg cgagctcacg ggccgcgctg agcaaagtgg acggtttggg
     3661 atgcagcacc cgcacgccgc ggttgaggtc ggaggtgggc tgcacgacct ggctcacgaa
     3721 cgggccgacc gccacgaccg tgctgaccgg cagtggctcg gcgcgcatcg cctggatccg
     3781 ctgcgccacg gcggtcgccg ccgccacggc ctcggtcgcg gggttcgccg tgccgtcctg
     3841 gctgaccagc ggccacccgt cgatcttcca ctgaccgccg agcggcgcct cgagcttcac
     3901 cgcggggtcg ggaaggtcga cgccgacgat caccagcacg cccttgggca gcacgacgat
     3961 cgcgtccagc gggacggggc aaccgggcgg ttgcacaccg gccagcgcca ccccaccgag
     4021 gacctcggta cccgccccgc acgccgtcag ggcggcacgg acgtccgccc caacggccga
     4081 aggctcagcg cccagacgga tcaaccgcac gagtccccac ctttccgcac gggtggacac
     4141 ggtagcggtc ctgggttggt caaccgcatc cagtcgagac gttgcgtgac acccgtcacc
     4201 gaaaagtgga tcactcgtta gatggattgc ctgtctatgt tcacggaggg tccatgtaca
     4261 aacgcgccgc acttctcgcc gtcgtgctcg tggccgcatc aacccctgtc gcggctgcgc
     4321 tgccgacctc gaccgtctac gtccacggtg ccgacatcgc cgccgcggaa caggcggtcg
     4381 cggccgccgg tctgcagaag atcaccagtt tccgcaagat cggcgtggtc gccgcgcggg
     4441 gtgactccgc gcgcatctca tcggcacggg ccaaggcggg cgtgacgcgc gtcgaggtcc
     4501 agaagccgat caagttcctc ggttcgacct cgcacaccgc cacccgcggt ctcgacgccc
     4561 gcaacagcct cgggctgacc ggtgcgggcg tgtcggtcgc ggtgatcgac tcgggcgtcg
     4621 acccgacgca cccgtcgttc agcggcggca agatcgtccg caacctcaag agcctgtgtc
     4681 tcgacggggc cactgactcg agctgcatcg tgccggtgcc gaacttcgtc gacaccgaca
     4741 ccacgtcgct gggcggccac ggcacccacg tcacgggcat cgcgatcggc aacgacgtgc
     4801 agctcaccgg tggcccggtg gtgcgcggcg cggcgccggg cgcgaagggc gtcgtgatct
     4861 ccaccggagc ggcgatcctc atcctcggcg cggacgccgc gctgaactgg gtgctggaga
     4921 accacaaggc cccgtgcggc gcaggcgtgc ccgcgtcgac gtgcccgccg atcaaggtga
     4981 tcaacaactc ctacgggcct tctggtggcg gtgcgttcga ccccgagtcg gtgacggtca
     5041 agctgcagcg tcagctcgtg gccgagggcg tcgtcgtggt gtgggcgaac ggcaacgacg
     5101 gtggcgacgg ttcggcgaac ctgtccaacc cgcccggcac cgacccgaca cccggcgtga
     5161 tctcggtggc gtcctacaac gacctggaga ccggcacccg cgacggcgcg ctgtcgagct
     5221 tctcgtcgcg cggtctcgcg acgaaccccg ccacgtggcc ggacatctcg gcgcccggcg
     5281 agaacatcac gtcgtcctgc cgcctgtacc tgccgatctg cgcgaccggc ctggccccgc
     5341 agaacgggcc gggactgctc gacctcggca cgttcaacac gatcagcggc acgtcgatgg
     5401 cggcaccgca catcgccggc atcgtcgcac agctgttcca ggccaagcct tccgcgaccc
     5461 ccgccgacat cgagcgggcg ctgaagtcct cggctcacaa gtacggcacc ggttaccagc
     5521 cggtcggccc ctacacctcg tcgttcgaca agggcacggg cctggtcgac gtggtcgccg
     5581 cggtaaacgt cctctagatc acgatcacgc atcgctcgac cggggagatc gggacttaag
     5641 acctgtatcc gccccggtcg ggtgatgatc gagctggttc ttatggcgga catgcctcaa
     5701 gtcgaggcag aatgcagcga acggggtttc acggtgatca cctcactcgg caaaggcgta
     5761 ggggaagacg tccctcgtcg agtagcggag gtcagcagtg agcacccgtg gcagcaccag
     5821 tggcgtggtc tacgtccact cgtcgccgtc tgcggtctgt ccgcacgtcg agtgggcgat
     5881 ctcgggcacc cttggcgaac gagtggacct caggtgggca gcgcaacccg cggcaccagg
     5941 ccagttgcgc gctgaatgcg catggacggc ggaggccggc accggcgcga aactcgtggc
     6001 tgcgctgcgc gcgtggccca tgcttcggtt cgaggtgacc gaggaaccgt ccccaggtca
     6061 ggacggtgag cgcttctgtt tcgcacccgt tctgggactg tggcacgccc ggacttcggc
     6121 caacggcgac atcgtcgtca acgaggacca gttgcgtgct ctcgcggcga gatcgcgggg
     6181 cggtgagtcc ttcgcacacg gagtggacga gctgctcggc gcggcgtggg acgacgcgct
     6241 ggaaccgttc cgccgcgcag gcgacggcgc gcccgtgacc tggttgcacc gcgtcggata
     6301 gtcctgagtg gaccccgcta ccgtttgggc agcggggttt cctcgtggtg cgtggggtcc
     6361 caggccagca tgagctgccc gtagagcggg gacgtcctga gcaggtcctc gtgcgtgccg
     6421 agcaacggct tgccgccgtc catgaccagc acgcggttcg cgcgcagcgc cgagctcagc
     6481 cggtgcgcga tcaccacgag aattccgtcc ctttgggcaa aaactcgttc gacgcgggct
     6541 tccgcggccg ggtccaggtg tgaggtcgcc tcgtcgagga tcacgatgct cgcggaggtg
     6601 acgtgcaccc gcgcgagtgc cagaagttgc gcctcaccgg cggaaagtcc ttcgcccgcg
     6661 tggccgaggg tggcgttcag gccaccgagc cggtccagaa ttggtttggc gccaaccttc
     6721 ttcaccgctt cgagcagttc gtcgtcagtc gcccacggtg cgagcagtgt gagattttcc
     6781 ctcacggtgc cggtgaagag gtaggtctcc tgcggaatca gcgcgatcgc gtggtgccgc
     6841 acctcgggaa cgaccaggtc gaccggtgcg ccgccgaaca ggacgcggcc gaggtccgga
     6901 ggcatcaggc cggtgagcag actggccatt gtggacttgc cgatgccgga cggcccgacc
     6961 acggccaggt ggtcgccggg acgcagggtg agtgagaggt ctcgcagcac cggttccgcg
     7021 tcctggctcc agccgaacgt gacgtcccgc agcaccacct cgccgttgga cgggacctcg
     7081 gtgccgatct tcttgttcgt ccgcggggcg acttcctgga gtcgtttgag cgcgaccatc
     7141 agccgcatca cgacagtgct ggtggtgcgg gccaggccgt gcaacgcggg gttcacgttg
     7201 ttggtcaggt acacgacagc cgccagcacc gcgccggtgg tcagctgccc cgacgcgacg
     7261 agcgggggag cgaacgccac cagcagcacg acgggtgtga aaccgccgag cgcgatcacc
     7321 gtggcgcgca acgagttcgc ccacgcgacg gtgacggtcg ccttggcctg ccggttcacc
     7381 tcggtcgcga tgtcggcgaa ggcttcctcc gcggccttgc acgcggcgac gtcccgcaga
     7441 ccggtcagca ccgcaccgga agcctcagcg gtgcgttcgt cggcgatcac ggcgtcgcgc
     7501 tggcgtttgg ccagtgaggg cagcagcagg gcgaacaaca ccagtgacgc cacgatcggc
     7561 agcaccacca gccagatcag cgcggccgcc gtcgtggcga gaccgatgag ggcggcgacc
     7621 gtggtgacca ggagcgcgcg ggcctgcacc aggactcccg cggtcgcgtc gcggaccacc
     7681 tcgacgtgcc gggtgatcat ggcgacggcg ctggcgtccg gggtccgccg gtgcgtcggg
     7741 tcgtcgagca cgccctggac gatccgggtg accagcgcgt cgcgcatggg ctcgacgacg
     7801 gcgccgagcc gcgcgaacac ctgccgctgg ccgagtgcgc ccgcgaccgc cagtgccgcg
     7861 aaggccagga gccagaggac gccgcttcgc ggatcacccg cggcgaaccc cttgtcgacg
     7921 gcggtgccga cgagccgtcc gccgaagaac gccgggacgc cttcgagcac cgaccagccg
     7981 agcaggatca ggacgccgcg gcggtgcccg gccagcgtgg agaggtagaa acgcatcact
     8041 cgcctccggt gaacacggct cggtagtcct cgttctccca cagctcctgg tgggtgccgg
     8101 tgccgcgcac cctgccgttc tccagccaca ccacgaggtc cgcccgagcc gctgtcgccg
     8161 cccggtgcgt caccaccaca cgtgtccggc cgggcagcgc tgtcgtgaga gccgcgtcca
     8221 ctttggcctc ggtgacggtg tcgaggctcg cggtcgcgtc gtccaggacg agcagagcgg
     8281 gatcgcgcac gatcgcacgc gccaagccga tgcgctgcac ctcaccaccg gacagcggcg
     8341 cttcggcgac cggtgtgtcg tagccctgcg gcaggcggat caggacgtcg tgcacctggg
     8401 cggcgacggc ggcgtcgcgc acctcggcct cgccggcgac ggttccatag ccgatcgaac
     8461 ggccgatcgt cctgcccagc agcgctggac gttcgaaggc gtacccgacc tcgccgtcgc
     8521 gcagcacctc gccggaatcc acagcggaca gtccgccgag gaccgcggcc agcgtcgact
     8581 tgcccgcgcc ggagctgccg accacggcgg tgaacgcacc ggccgggatc gtgaggttca
     8641 cgtcgtgcag tacgccggtg acgccggcac cgcgcagttc gatcgcgccg gactccgggg
     8701 ccacgggtgc agcacggtcg ggcggtgggg tgtccagcac ctcggcgatc ctgctggcgg
     8761 aggctcgcgt gcgctccagg gcggtgagct gcgggatctg gccgacgatg cccatgccca
     8821 gcgcggcgta gccgagggcg gcgagcacgt caccggggct cagcctgccc tccatcacgc
     8881 cgaaaccggc ggtgatcagg acgacgacct cgacggccgg caacagcagg cccgcacgcc
     8941 acatcatctt cgcctgagtg cgccacatgc ccgcaccggc cgccgccagc cggggcagcg
     9001 gctgcagcac ccggtcggct tcgcgcccgg cgatgcccgc agcggcgatc gtgcgcttgc
     9061 ccgacacggc gtcgagcagc cgcgccgaca cgtcgccgga aacctcctgg taggccagca
     9121 cgtcgtcggc ggtgagctgc atgtgcgtgc ggaccaggaa catcgccagc ggcacgctca
     9181 ccacgaacac ggcggccagt cgccagtcca tcaacgccag cgccacgacg gagcccaccg
     9241 aggacgccgc ggcgatggcc agcgagatca gcgtgaccac gatgccgccc gcgttgccgc
     9301 agtcgccggt cacgcggctc accgcgtcac cggcggcgaa cggcgagggg tgcccgagcg
     9361 ccagaaggtg gcgggacagg cggtgccgga gccaggccgt ggcccggctg gtgatgctcg
     9421 cggccagcac gatgccgatc gcgtcaccga tgatctcggt tgccgccatt ccgagcagcc
     9481 acagcagcgt gaacagcacg aacgtgccgc cgagcgccat gtcgacggca tcggcgagcg
     9541 ccgaggggat cagcagtccg ccggtcgtgg cgacagcggc gttgagcagc agcagccacg
     9601 gacggtggtc gcggcgcacc acggagaaca gcagggcgtc accgggtttg gccatcggct
     9661 gttcctccgg aagtcatgag ggcgcatcat gagcgagggc ccgacagctg gccggctgcc
     9721 gggccctgca gagggtgggt gagcggcata cttcgcctat gccgctcatc taccgcggtg
     9781 tttcagttgg agctcagctc agcaggccag caggctgacg gtgctgtgcg agcaggggag
     9841 cagcagcgac gcgttcgacg cggtggtgga gccaccgccg ccgccacccg agccaccgga
     9901 ggccatcacg ctcgtggtct cgggcgtctc gaggtcctgc atgtcaagga tgaaacccat
     9961 gacaactctc cttgttcgag gaatctttcg ggggttactg ctaccggttc gctagaaccg
    10021 gggcctgtgt cctgcccagg aagggcagtg gtggacgtcc gtccactgtg gaggcgatgg
    10081 cgagcaggac gcccgcaccg ccggtgttga gatccatgga aagccggcgc agctgcacgc
    10141 cggggaacgc gagcccgccg ccgtaccgca cggcgtgcca gccgagtgcc cgcaggtgct
    10201 gctggatcgc gcggtcgagc cgttcgtccg gcttgtgcgc ggccgcctgg gcgagcgtgg
    10261 ccatcagtcc ggccctgccg agcgcgaacg ccggctggat cacgaactcg ccggtgcagc
    10321 cggtgagcag ctcgggcagc ttctccacgc acggacgttc cggcgccacc gcggcgaact
    10381 cggtgagcac cagcgcgatg cccgcgccgc cgatgcccac gtacggcagc gaccggaacg
    10441 tgccgtcccg cacctgcaga gagccgtcca gcgcgaccat cgtctcggcc aggtcgcgtt
    10501 ccagcgcctg ttccgacagc ctgagccagc gccgttcgcc ggtgcgctcg aacatccgca
    10561 ggaagaacag cgcgggaccc gaccagccgt gcagcaggcc ggccttcgcc ttgtcaccgg
    10621 gtcccggtgc gccggccagc tgctccgcga gtcgttcggc cagctcctcg gcccgcgccg
    10681 cgaagccgtg gtcctcacgg acgtccgcga agtgcagcaa gttgaggccg atgccggaca
    10741 gtccagcgct cagcccgtgg tcccgcgtgg tggcgacgag ctgcgtgtag ccctcgacga
    10801 gctcggtcgc caggtcgtgg tggccgaagt tctccagcac gtgcgcgatg ccgtgcgcgc
    10861 cgacgaagaa gccgggctgc ttcggaggat ccttcctgac cgccttgatc agccagtcct
    10921 cgtgctcggg gtagcgaccc tcgccgctga cgtcgagcgc gtgcagcaca cccgccgcgc
    10981 cgtagccgaa gcacgtgccg ccgacctcga actgctcgat gtcgccgggg aacaggcggt
    11041 cttggcgttg cggtgtcgcg ctgtgcagga tcgccgtcgc gatggacttc ctgacgacgg
    11101 tccagtccgg ttccgggtcg tcgaacgcgg tgaacgcggg ctcctccggc gggtccacgc
    11161 gcggcgtgag cacgtcgacg atcgaccggc agtactcgtc gccgagaccg aagcgctgct
    11221 ggatgacgtg cacgtgctgc ttcagcttcg ccggcgagag ctccagcacc gcgttgagcg
    11281 gcaggaagat ccacagcttg agcgccgcga gcgggtactc gtcgatctcg aagccctcgc
    11341 ggtcgctcgg ggcctggaat cccggcgcgc cgagcgtcgg cctcttgacg tcctcgatcg
    11401 tcgacgacag ctcgaagtcg atcagcgaga cctcatcgtc gtcgtccacc aggatgttga
    11461 gcgtgtgcag gtcaccgaac acgacaccgc gttcgtgcac ccgtgccatc aggtcttcga
    11521 ccttggtgac gagtttcagc gctcgttccc ggtactcggc gagctgctcg tcggtggtgt
    11581 ccttgtgcgt caacgggtag ttgtgaccga gccactgccc gagcgagcgc cccggcatga
    11641 actccatggc gacgaagagg tgctcccact cggtgaagcg gtcgtacacc tcgggcacgc
    11701 cttggacttt ctccagcttc gtgaggatcg tgtgctcgag ctccagccgt gccacggcgt
    11761 cgcggccctc gcggtcgagc ccggcatgcg gccgcgcctc cttgagcacg acctccttgc
    11821 cgtcgctctt gcgcgtcgcc aggtagacac cgccgccgtt ggagaagtgc agcgaactct
    11881 tgatctggta cgggaacttc gcgggatcac ccgcgttgcg ctcggccagg tgcggcgcca
    11941 ggaactccgg cagctcgacc cactcgggca cgctgaagac gggcttgcgc ttgtcgggga
    12001 tgagcgtgcc gtccggcccc tcgatggcga ggacctgctg gccgtcgacc tccagccact
    12061 gctcggagaa cccgccgtag cgcacgtaga gcggaccctt gccgtacctc aggtcgctga
    12121 ggatgtaggc gccgtgctcg ccctgcagcg tggctccgag ctcggtgagg atgctctgga
    12181 gctgctcggt gccggcgggg tagatcgtga tcagcttgcc gctgccctca cggggcgcgt
    12241 acttcgagtt gcgggccagc acgatcgaga tcgtcggcag gtacttgaac ggaattcgcc
    12301 gttctacgca gtagtcgaaa gtggccttca gaaccctgct cgcgttgtcg agaccagcgg
    12361 agacgtggat cttccagccc tgcttcggca gcgtgacccc ctgcgggtgc agatgccgcc
    12421 acacgttccg ctcggcctgt acccagccgg ccggcagttc gggcaggtca cgcgaaaagt
    12481 cgtctcctgg gaggtcgctt tcggtgctgc tctgcagatc gtagaaccgc cgatctgcga
    12541 agcagaacgc ctcgtatctg aggtccaccg aaattccctc ctcgacggtt ttgcgatttc
    12601 gtttacgcgg catattcccg cacaattcag cggctatggc caatccgcca ttaggggcgt
    12661 atgggtgggc cgttcgtgtc cgaaagatga tcggttaccg gtgcgtatgc cacgctccgt
    12721 gatgaggttt gggaccgtct cacccgcctg cgaggtttgc tgatcggtga gtcagcgcac
    12781 gcgtcctggg gttttgctaa acggaactgt atcgttgcgg atgggtgcag ctctctgagc
    12841 tgcggtattc cacatggatc tctacgtata gttgggggtg cgcaaccatc gtgcacgcgc
    12901 tgtgttccgt actcttttcg ggtgaagttg taagtgggtt ccgatgcgtg tttagtgcgg
    12961 ctgatcggcg gtgtcgggtc gcctgaaagg acccattcgg aggattacat tgcttatcac
    13021 gtttgtatgt agcactcgtt gtctcgctac atgcaacttg catctagggt gaatgtaatc
    13081 tttcgggtga agtttatgtt ttgatgtaac ggaacgatgt ttttgtgagt ggcgctctgg
    13141 tggcttgaag ccggggccgg ccgggtacac gcgcgtgggg tgtgttctcg ctgctggagt
    13201 cgggtggggc caccgggtcg tgggtgccga cgggggctgg gctgtgggcg cggacgcggc
    13261 ctggccacgg gtgtcggcga ggccggcgac gtgtcagcgg gcagtcgggc cgcaggtcgt
    13321 gggcgggcgg ctaggctgtt cgtgtgggga gcgtggctag ccgctggctg gtgccggccg
    13381 tggtggtgat caccggtgcc tcggtggcgg ccgggatggt ggggcggacg gtctactcgc
    13441 gtcctgccga ggccaagggt gagccggtgg tgccgtcttc ttcggtgtcc ggcgcggcgt
    13501 tgcccggggg ctctgaggtt cggttgagtc ccgactcgtt cacgcatcct gatcggacgt
    13561 ctgtccagaa ggtgctgcag aagtacttcg acgccatcaa cgagcgggac ttcgccgggt
    13621 ggcgtggggt ggtgtctgct cggcgggcct cgcaggctgt tgagaagacc tggctggctg
    13681 cttatgagac cactcaggat ggtggagtgg tggtgcagcg ggtcgagtcc gatgtggtgg
    13741 ctcggcggtt gcgggtgttg atcagctttg tgtccacaca ggatgtttcg aaggctccgg
    13801 ttgccatgcc tgaaccctgc atccggtgga gagttgtgta tgtgatggtt tgggagggtg
    13861 gggagctcaa ggtggatgag gcgccagaga accggacccc tcagatggag aagtgttgat
    13921 ggggatcttg gctggcgcgt cggtcgcgca ggtggttgcg atgcgtgggg caggcccgtc
    13981 acgagccgtc ccggaggggc caacaatcgg gcacgactcg tgacgggacc cacccacccc
    14041 acggcggccc gcgcgttgct caaagcagct cggctccgcc gtcgccattg ctcggcttcg
    14101 ccttcgcgag atgctgtgtg ctggcggctg ggtgcgcgtg tggcgtctgc aagtaccgcc
    14161 aacgcatgat cgaaacgctt gtaactaccg ccaacacgtc gaacgccccg gtccgcttgg
    14221 cgggccgggg cgtgtcgagg tgtgctcagg ccggggtgaa ggccagcgcc acgttgtggc
    14281 cgccgaagcc gaacgagtcg ttcaccgcgg cgtccagctt gatcttgcgg ggctcgcctg
    14341 ccaccacgtc cagcgtgacg gccgggtcca ggttctccag gttcagcgtt tggggaacca
    14401 cgccgtcgcg gatcgacagg acggtcacga tggcctcgac cgcgcctgct gcgcccagga
    14461 ggtggcccag ggcgcccttc ggggcggtca ggaccgggtg gtcgccgatc gccttgcgga
    14521 ttgccacggt ttctgcgacg tcgcccaccg gggtggaggt ggcgtggcag ttcacgtggc
    14581 ccacgtcgga cgggtcgatg ccgccggacc gcagggacgc ggcgatggca cgggactggc
    14641 cgacgccctc ggggtccggg gccgtgatgt ggtagccgtc ggccgaggtg ccgatgcctg
    14701 ccaggcggcc gtagatcttg gcgccacggg cctcggcgaa ctcgcggcgt tccaggacca
    14761 tgacgcccgc gccctcaccg aggacgaagc cgtcgcgggc cgtgtcgaac gggcgcgagg
    14821 ccttttccgg ctcgtcgttg cgggtgctca tggtgcgggc ctgcgagaag cccgctaccg
    14881 ggattgccgt gatgcacgct tcggcgccgc ctgccacgac cacgtcggct tcgccggcct
    14941 tgatcatgcg gtaggcccac gcgatggcct ccgcgcctga cgcgcaggcg gagaccgggg
    15001 cgtggacgcc tgcctgggcc ttgagttcca ggcccacgtg ggcggccggg ccgttcggca
    15061 tcagcatcgg gacggtcagc ggggacacct tgcgcaggcc ttgctgttcc aggaggtcgt
    15121 cctgggccag gagggtgatc gcgccgccga tgcccgtgcc gatgatgacg gcgaggcgct
    15181 ggcggtcgac ggtgtcgtcg ctgtggccgg cgtcttgcca cgcctggcgg gacgccacga
    15241 tggcgacctg ctcggagcgg tccaggcgcc ttgcctcgac gcgggggagc acctcggtgg
    15301 ggtcgacgac cagctgcgag gcgattttca ccggcagctc gtacttctcc acccagtcgt
    15361 gggtgagggg gcggaccccg ctcttgcccg cgagcagtgc gtcccaggtg gacgtgacgt
    15421 caccaccgag cggggtggtg gcacccagcc cggtgatgac gacgtcgatg tccgaactca
    15481 cttgttgctg gtgatgtagt tcaccgcgtc accaacggtc ttgaggttcg ccagctcgtc
    15541 gtccgggatc ttcacgccga acttgtcctc cgcctggacg gcgatctcga ccatcgacag
    15601 cgagtcgatg tcgaggtcgt ccacgaagga cttctcagcg gtgacgtcgt cggcggccac
    15661 accggcgacc tcttcgacga tctcggcaag accggacagg acgttgtcgc tcactgaagt
    15721 tccctttcga ttgaaacgat ggaaaaaccg ggggtactca tgggcaccgg accacctgtc
    15781 ccgcgtagga cagaccagcg ccgaaaccga ccatcagcac cacgtctccg ctggagatct
    15841 cgcccgcggc ccgcatgtgg tccagtgcca tggggatcga ggccgacgag gtgttgccgg
    15901 attcgacgat gtcacgagcg accttcaagt cctcgcgcgc acccttggca cgcaggcgct
    15961 tggcgatcgc ttcgatgatc cgcaagtttg cctggtgcgg ggcgaagacg tccacttcgg
    16021 acagctcgac gcccgcgagt tcggcggcgc ggatcgccac gggcgcgatc tgggtcgtcg
    16081 cccagcggaa gaccgactgg ccttcctggt ggatgaagga gtcgcggtcg gtgatggtga
    16141 tcgtctcggc gaggtcaccg gccgagcccc acgccacggg gccgatctgg ttctcctcgc
    16201 tggcaccgat gacgacggcg cccgcgccgt ccgcgaagat gatcgcggtc gagcggtcgt
    16261 cctggtcggt ccagtcggtg agcttctccg cgccgatcac cagcacgttg cgggccgtgc
    16321 ccgcgcggac gaggtccgcg ccggtcgcga cggcgtagca gaagcccgcg cacgcggcgt
    16381 tgaggtcgaa cgccggcgcc gccttcacgc cgaggcggtc ggcgatctgc gcggcggcgt
    16441 tcgggatggt cgacggcatg gtgcacgtcg ccacgatgac ggcgccgatg tcggccgggt
    16501 cgattcccgc gtcctcgatc gccttcccgc ccgcgatgac cgccatgtcg acgacgccct
    16561 cgtccttggc ggcgaaccgg cggttcacga tgccgacgcg gtcgcggatc cactcatccg
    16621 aggtgtccat gcgcgcggcg aagtcgtggt tgctcaccac cgtctcgggc tggtagctgc
    16681 cgaggccgat gatgcggcta cccgcggacg tccgcggggc ctggaaggtc gtcactgagt
    16741 tgctccaacg gtgtcgaaga gctccgccac cttctccagc tggtcgggcg tcttcagggc
    16801 gagggtggcg gtgcccttca tcgcacgctt ggcgagaccc gtgagagcgc cggcgggcgg
    16861 cagctcgacc gagccggaca cgcccttccc gacgagcgtc gcctggcaga cgtcccagcg
    16921 caccgggctg gtgacctggg agaccaggcg gcgcagcacc tcggtgccct cggtgacggc
    16981 ctgaccgtcc ttgttggaca gcagcggcat caacgggtcg tgcgtggtga cctcggcggc
    17041 acgcgcgcgc acagcgtctt ctgcgggcgc catgtacttc gtgtggaacg cgcccgcgac
    17101 ggccagcttg cggaccttcg ccgtgcccgg cggggtctcc gcgagctcgt cgagtgcggg
    17161 acgcggaccg gccgcgacga tctggccggc gccgttgcgg ttggccggca cgaggccgag
    17221 ctcatcgagg cgcgcgagca cctcctgctc gtcgccaccg agcaccgcgg ccatgccggt
    17281 cggctcgagc gcgcacgcct ctgccatcgc ggcaccgcgc acggcggcca gtgcgaccgc
    17341 gtcgtcggcg ctgatgacgc ccgcgatcga cgcggcggcc agctcgccga ccgagtggcc
    17401 cgcgacgatc acgccggcgg gcagctcgac gcggcggcgc agctcaccga acgcgagcag
    17461 cgcgagggcc acgaccagcg gctgggtgat ggcggtgtcg acgatctcct cggcctcggc
    17521 ggtcgtgccg aggcgcacca ggtcgaggcc cgtgatctcc gaccacgtgc gcacctgctt
    17581 ctcggtcccc tccagttcga gccagggggc gagcatgccg ggcgtctggg acccttgtcc
    17641 gggcgcgagg agtgcgatca cgtggattac taaagctggt gaacccgccg gtaccccatg
    17701 ctgtaaagaa cgaagtccgg cgatggtatt tgtagagacc ctacaaaagt gtcggccagg
    17761 tgaacactgc gcggcgtatg cccagctcag cacaccggca ggtcgtttgg ccatcaccct
    17821 aacggatgtg tgcgaagtcg gtcacagatc gttcgctacc acaggccccg tgcgcgggca
    17881 aggcgtccta cagacaaagc gacgcgaagc acaagtgcat ctcgagcgtc atgtgcattt
    17941 cttccggtca tttcctgaac gcgccgaagg cgatatctga ccgtgttcgg gtgcacgaac
    18001 agtcttttcg cgcacgtctc cagcacgccg ccgacctcca ggaacgcgtc cacggtctcc
    18061 agcagcgcgc cgccggcgtc ctccagcggc cgggcaaccc tgtcgacgag ctgccactcg
    18121 gcctccgggt cgcccgcgag cgcccgttcc ggcagcaggt cgagcgagcg gacaggcctg
    18181 ggcgcggcgg gccagcccac gaccgcgcgc agcccgctca acgcgtcgct ggcgctgcga
    18241 tgggcctccg cgagcgaggc gaccgtgggc cccgccacca cgggcccctc gccgaagccc
    18301 tcggcgatgc ggcccagcac gtcctcaccg gtctccgtcg gcccgccgag cacgacgacc
    18361 agccgtgagc cctgcacgga cagcagcacc ggccggccgg cgcgggcggc cttgctgcgc
    18421 accgagtaga tgatcgccgg tggatcctcg ccgcccggat tgccgaccag caccgtcgcc
    18481 tccagcgccg gatcccagcc gagcgcggcg gccctgctca gcaacgactc ctcggggtcg
    18541 ccacgcacga cgccgtccac gaccagcgct tccagtctgg cgtcccacgc accgcgcgcc
    18601 tcggcggccg cggcgtacga ggtggcggcg gagaaggcga tctcccgccc gtaccgcagc
    18661 acgccctcca tcagcagcgc gcgctcggcc tccgtaccgg ccatcgccgg catctgctcc
    18721 tcgaagtgct ccagcgctat ccggaccagc tcgacggtct ggcgcaggct cacccagcgg
    18781 gagatgtcct tcggcgccga ccggaacgcg tccgcggtga gccggatcgc ctgctgccgg
    18841 tcgtgcagcc actcgacgaa gcccgccacg ccgttctgga tcagcagcag cacgctggcg
    18901 cgctggtccg cgggcatccg ggcgaaccac ggcagccgct gctccatctc ggccacgctc
    18961 gcggtggcga gcgctccgga cgcgcgttcg atcttgcgca tcgtgcgggc ggagagggtt
    19021 ggcgggtgct cctccttcgc ctcggctgcc ttggtcatac ccgcagctta aggccctggg
    19081 ggtgacatca ccgggacggg tgacagaacc ctcgccttcc tttcaacggc cataccttcg
    19141 gatagcaagg gtcattcgtt cggcgcggag gtttcgtctt gcgtaggttc ccggctttcg
    19201 tcctcggcat ggtggcactc accgccacgg gcgtgactgc ctccgccgat cctcccgatc
    19261 ccctcgcgga gtaccacgcc cagccggtca agtgggcggc gtgcagcggc aagctcagcg
    19321 ggctggagtg cgccacgctc gtcgcgccgc ttgaccacgc caaaccggcc ggcgaccgga
    19381 tcaacctgac gatcagccgc aggaaggcgg cggcgcagga ccgcagacgc ggtgtgctgt
    19441 tcaccaatcc gggtggtcct ggtggctcgg ggctcagcct gccgctgttc ctcgcgaagt
    19501 ccgagctcgc ccaggtctac gacgtgatcg gcatcgaccc gcgcggcgtc ggtggttcga
    19561 cggcgctgaa ctgccgtgcg gcgcccgcga tcgccgcgcc ggactcgcgg ccggcggacg
    19621 gcgagttcgg caagtgggcg gccgaggcgc gcgaggccga ggagtcctgc cagaggtcgg
    19681 ccggcgggat ccggcagttc atcagcaccg cgaacaccgc gcgggacatg gacatcgtcc
    19741 gtgcggtgct cggcgaggcg aagatcaact acctgggtta ctcctacggc acgtacctgg
    19801 gcgcggtgta cgggacgctg ttcccgaacc gcctggaccg cagcgtgctc gactcggccg
    19861 tgcacccgga gtggatctgg cacgagcagt tccgccagca ggccgtggcc taccggcgca
    19921 gtgtcgaggc gtgggccgcg tgggtggggg agcgcaacca gaagttcgcg ctgggcaagt
    19981 cgcgggacga ggtcctggcc gaggtggaga aggtcgcggc gaagctgcac accgcgccga
    20041 tcggtgagca cgaccggtct tccttcgacg gcgcggtcgg tgtgggctcc cgctaccgtc
    20101 cactgtggtc ggacctggcg tcgatcgtga tcaagctgcg gtctggcgag aaaccggaga
    20161 acaccgaggg tgccaaggcg gggcaggtgc tcgcgaagac cggtctgcgg gaactgcggt
    20221 ccggcgtgtt cgacacggtc acctgcgagt cggactggcc gaccgacctg cacgtctact
    20281 acgaggacat gcggacgttc cgcgagcgct acccgttcgg cttcggcatc gtcagggccg
    20341 cgccgatgac gtgcacgttc cggtcgttca ccccgccgga gcagccggtc aggatcggcc
    20401 gcagcggtta cccggtcggc gtggtcgtgc agtccgaggg cgacacgcag acccagtacg
    20461 cgagcggccc ggcgatggcg gcgcggctcg gacacaacct gatcaccgtc atcgacgagg
    20521 gcaagcacgg catctacaac ggcggcaaca agtgcgtcga cgagaaggtc aaccggtacc
    20581 tgatcgacgg ggcgctgccg ggcagcagct ccgagtgcac gggtgacccg cggccggacg
    20641 tgccgaagga cggtcagggt ggtgccgcgc cggcgttgtc gccgaaccgc atccagggct
    20701 acctggaagg gcgcggactc tccgcccggc cgtagaaatg tggaagcgcc caccacggag
    20761 cgtggcgggc gcttccctct ccccggtccc caccggtagc tccactctgg actgtactga
    20821 gacaaaaatc cacgtcagcc accctttcgt gtcacagtgt cgaagttgct gagcggtgtg
    20881 atccacgaaa cgatcaactg gtcggatctt cactcaccgc aacttcgttc taggagggcc
    20941 cgtgggctcg caaatcaccg agggcctggg ccaggcgtgg gcgatgatcg ccacgttcgt
    21001 gccgaagctg ctcggcttcc tgctcgttct ggtgatcggc tggttcatcg ccaaggctct
    21061 cgccaagggc gtccagttcc tgctcaagcg cctcggcttc gagaagctcg tcgacaagtc
    21121 gggtctgaac agcgccatga ggcagtcgtc gatggacgcg accggcctga tcgccaagat
    21181 cgtgtactac ttcgtgctgc tcatcgcgct gcagctggcg ttcggcgtgt tcggcgcgtc
    21241 caacccggtc agcacgctgc tgaacgaggt gatcgcgtac ctgccgcgca tcgtcgtggc
    21301 gatggtgctc gtgatcgtcg cgtcggccat cggcaccgcg ttgaagggcc tcgtgaccgg
    21361 tgcgctggga cagcgttcct acacccggat catgggcaac atcacgtacg gcttcgtgat
    21421 ggcgctgggc atcatcgcgg cgctcaacca gctcggcatc gcgatctcgg tgacgatgcc
    21481 ggtgctgatc gccgtcctcg ccacggtcgc cggcgtgatc gtcatcggtg tgggtggcgg
    21541 cctggtccgc ccgatgcagc agcgctggga gggctggctg aaccgcatgc aggacgaggc
    21601 gcaggccatg tcgccgatgc cgcgtgcgtc gcaggagatg ccggccacgg tcggcgtccg
    21661 tccgggtgac gccccgacgc cgcccgcggg cacgccgatg cctgagaagt agttctcacc
    21721 tcggagaagg ggcctcgcgc ggcggggccc ctttttcgtt gtttggcggt tctccagctt
    21781 ccgtccagcg cgcgcacgga gtctcgtgtc cacccgaact gtccgctgtc gcggtggagg
    21841 acccatgaaa gcccttgtgc tgtccagagg agcgggaaca cgactgcgtc cggccgggta
    21901 caccctgccg aggcagctcg tccccgtcgc gaacaagccg gtggtcgagc acgtcgtgga
    21961 gaacctgcgg gacatcggga tcaccgagat cggcatcgtg gtcggcgagg gtgagcacga
    22021 ggtgcccgaa ctgttcggcg acgggtcgta cctcggtgtc tcgatcacct acctccggca
    22081 ggacgcgccg ctcggtctcg cgcactgcgt gcggatcgcc cggccgttcc tcggtgcgga
    22141 cgacttcgtg atgtacctgt gcgacaacgt gctggccgag gggatcgggc agatcgccga
    22201 cgagttcgcg cggctgaggc cgtccgcgca cgtgctcgtg gacaaggtgg aggacccgcg
    22261 cctctacggc gttgccgagg tggacgagaa ctcgcgcgtg acgcggttga tcgagcagcc
    22321 gcaggagccg cgcagcgacc tcgcgatgat cggtgtctac ttcttcacgc ccgcgatcca
    22381 ctccgccgtc gacgcgatcg aaccgtcgtg gcgcggcgag ttcgagatca ccgacgcgtt
    22441 gcagtggctg gtgacgcacg agcgcgatgt ccgggcgcgg gtctactccg ggttctggaa
    22501 ggacaccggg accgtcgagg acgtgctgga gtgcaaccgc gagctgctga tggggctgcg
    22561 gacggaca
//
