LOCUS       NZ_QLTT01000006        22043 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Lentzea atacamensis strain DSM 45479 Ga0215649_106, whole genome
            shotgun sequence.
ACCESSION   NZ_QLTT01000006
VERSION     NZ_QLTT01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea atacamensis
  ORGANISM  Lentzea atacamensis
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 590308)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 590308)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Expected Final Version            :: No
            Genome Coverage                   :: 111.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 11:04:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,181
            CDSs (total)                      :: 9,101
            Genes (coding)                    :: 8,972
            CDSs (with protein)               :: 8,972
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 6 (5S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 27 of 129
            Pseudo Genes (incomplete)         :: 107 of 129
            Pseudo Genes (internal stop)      :: 5 of 129
            Pseudo Genes (multiple problems)  :: 10 of 129
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:43:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 276479
            Orig. end                         :: 298522
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QLTT01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22043
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="1"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22043
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22043
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12043](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12043
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            782..2002
                     /locus_tag="C8D87_RS27020"
                     /old_locus_tag="C8D87_106294"
     CDS             782..2002
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005466189.1"
                     /locus_tag="C8D87_RS27020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106294"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_112228843.1"
                     /transl_table=11
                     /translation="MPEAVIVSAARSPIGRAGKGSLKDVRPDDLAAQMVRAALDKVPQL
                     DPAQIDDLMLGCGLPGGEQGFNMARVVAVLLGQDSLPGTTVTRYCASSLQTTRMALHAI
                     KAGEGDVFISAGVETVSRFAKGSSDSWPDTHNPLFADAEARTVSVAQSGADEWVDPRSL
                     GVVPDIYIPMGQTAENLALLKGVSRQEMDEFGVRSQNLAEKAIADGFWAREITPVTLPD
                     GTVVSADDGPRAGVTYEAVSALKPVFRPDGRINAGNCCPLNDGAAALVIMSDTKARELG
                     ITPLARIVSTGVSGLSPEIMGLGPVEASKRALALAGLSISDIDLVEINEAFAAQVIPSY
                     QDLGIDLDRLNVNGGAIAVGHPFGMTGARITTTLINSLQFHDKQFGLETMCVGGGQGMA
                     MVIERLS"
     gene            2164..2373
                     /locus_tag="C8D87_RS27025"
                     /old_locus_tag="C8D87_106295"
     CDS             2164..2373
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D87_RS27025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D87_106295"
                     /product="hypothetical protein"
                     /protein_id="WP_109632219.1"
                     /transl_table=11
                     /translation="MPYVWWQSEYDLQCHAFSLDQANGSRSFYEAVCEHSVPDERVSRA
                     QAGALCTTCLIKVGTQLPDVRWRA"
     gene            complement(2370..3119)
                     /locus_tag="C8D87_RS47965"
                     /old_locus_tag="C8D87_106296"
     CDS             complement(2370..3119)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="C8D87_RS47965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106296"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_233442302.1"
                     /transl_table=11
                     /translation="MSKRFGEAMRLMRRRNGQDCETGFAMLKPHAAEHLDELIEEFHRE
                     EDDQGLRAWLLELIGEAGDPRALPLFVAHLDDERFGDWAIWGLEKLGTKEARTALYRHR
                     SNKHTWGRSVDHAYRLEMTPPAVDDYLRLRKESGLSARTVEEAENGINGAWASAHVVHV
                     ESGETVGMGRVLSDGGWYFHIIDMAVLPHHQRKGIGDAIMTALLDRIGEHAPNAYVNLL
                     ADPPGRRLYERHGFTESAPASVGMRRV"
     gene            complement(3185..3985)
                     /locus_tag="C8D87_RS27040"
                     /old_locus_tag="C8D87_106297"
     CDS             complement(3185..3985)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005155843.1"
                     /locus_tag="C8D87_RS27040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106297"
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="WP_109632215.1"
                     /transl_table=11
                     /translation="MRSSSNPAFRNLPTGGGYGGYAGFGQPEAGYQQAPPPLTSERPMT
                     IDDVVTKTGITLAVVAATAVVTYVMQWWNLLFPAAIIGLVLALIIMFKRMPSPPLVIAY
                     AAVEGIFLGAFSGIIGAMIDRWTGPGQGVVVIGQAIIGTIGVFAGMLIVYKTGAIRVTP
                     KFTKWITGAIIGVAVLMLFNLIMSFFTDGGLGLRNGGALAIIFSLVCIGLAAFSFLIDF
                     DAADQAIRAGVPAKFAWQIAFGLTVTLVWLYTEILRLLSYFNSD"
     misc_feature    complement(4174..4191)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.84"
                     /tool="antismash"
     gene            4304..5692
                     /locus_tag="C8D87_RS27045"
                     /old_locus_tag="C8D87_106298"
     CDS             4304..5692
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098213.1"
                     /locus_tag="C8D87_RS27045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106298"
                     /product="hypothetical protein"
                     /protein_id="WP_112228844.1"
                     /transl_table=11
                     /translation="MGWKRLAAVAVVSGLALLTAPTTATAVGVKGIGHNASGLQPNATP
                     GSEWHGSYVWQNKHVWCVQYALPAPDSNVGYKEGDELLTKAGKKLPSDVAANISYLLLR
                     YSTTKSAEEAAALAHLLHTWTSPVDGNVNLGATDPKYLAYDSAFYASKLPPAVMDTVAR
                     LKADAEANRGPWTLSATAPKEPLIIGTESSWTVSLVKANGQGVPSAPIDFTLTDATLVD
                     GSVGGKATTGADGSPATIKILPTGPKPSIAANADSPADKPVVHQPISTDNMQRMVTTGG
                     EKKLSANATGQAKTAPGKVKITKIDSETKKAIAGVALRVTSKDQTKPALKQDDTELVGT
                     DGKPLVLQTGADGTVEVPDLRTPQEICLVEVAAPKGYEEFFDPKAPPASCGTLAAGQTL
                     ALELVNKPNKPVVPSTIPAGQDGKTPVATASFETQLRPGVMLAVGGLVLLGAALAGFLV
                     WRRQ"
     gene            5677..6381
                     /locus_tag="C8D87_RS27050"
                     /old_locus_tag="C8D87_106299"
     CDS             5677..6381
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005459162.1"
                     /locus_tag="C8D87_RS27050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106299"
                     /product="class F sortase"
                     /protein_id="WP_215732502.1"
                     /transl_table=11
                     /translation="MAQAVSPKAFLTGALVAGVAATSVLVTASGTEVLKGHAVADEIPV
                     VGPGPVADSLSTGRGADLTGLVGGANTANAKPAEPTQPQPAPPKAGPGSVRLPSGGTAT
                     LVRREVKDGVLPVPDGIGEATWWGAELAAQEGATVLAGHVDWKGARGPFAELWQAQNGR
                     EVVIADSAGKEFKFRINQIETVRKEELPARAVEFFGPRGPHRLVLVTCGGTWIGGQQGY
                     EANRVVIAEPVA"
     gene            6439..7587
                     /locus_tag="C8D87_RS27060"
                     /old_locus_tag="C8D87_106300"
     CDS             6439..7587
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098211.1"
                     /locus_tag="C8D87_RS27060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106300"
                     /product="polysaccharide deacetylase"
                     /protein_id="WP_146771881.1"
                     /transl_table=11
                     /translation="MTTGLALALALVLVMTLGPTKDQQSQADAGPLPMAPRLPAPKDAG
                     PTPTVPAPSPEQLQQQPWMHKLAPGEKPPQFVLFSFDGAVSKQHWDKVLPIAREKKAHV
                     TGLLSGVYMLADQDKMQYQPPAGLKRGVSDISFGGSKQDIAARIGYLNQVIDEGHEIGT
                     HYNGHFCSGGTQPSVDKWDSKAWNEELAQFKQIVDRARAAGFKLADGAVRGGRTPCLEG
                     NWDQAFPAMAANGLVYDTSKVALGVQWPSVQNGLYEFPMPEVRVPALGRQVVMMDFNLW
                     YALNAARDEPHRATEFAQIVFDTYKSVHQAALNGNRAPLVIGNHFNEWNGSAFSNAMEQ
                     FLAYVCDKPETVCATYTEVIQWMQLQEPAVLDQLRRMPAARN"
     gene            complement(7674..7880)
                     /locus_tag="C8D87_RS47970"
                     /old_locus_tag="C8D87_106301"
     CDS             complement(7674..7880)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D87_RS47970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D87_106301"
                     /product="hypothetical protein"
                     /protein_id="WP_233442303.1"
                     /transl_table=11
                     /translation="MTNPVKTWPTSQAGPAGIGYCKNALYVGPVTDRRVWKIPVNGTTL
                     GTPQAVFTSYGRVRAVAPAPDGT"
     gene            complement(<7989..8060)
                     /locus_tag="C8D87_RS47975"
                     /pseudo=""
     CDS             complement(<7989..8060)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019607.4"
                     /locus_tag="C8D87_RS47975"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEFGPDGFLWATTGDGQHTSTAQN"
     gene            complement(8521..9516)
                     /locus_tag="C8D87_RS27070"
                     /old_locus_tag="C8D87_106302"
     CDS             complement(8521..9516)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670614.1"
                     /locus_tag="C8D87_RS27070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106302"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_109632207.1"
                     /transl_table=11
                     /translation="MGARRSAYAGVLALAVGLSSSPLASAAESGEVGTMAVKTIATGLK
                     QAWSIDFLPDGTGIFTQKDAKTVSTITKDGKVTKVGDIPGVSVTKEAGLLGIAVSPTYA
                     ADKTLFLYYTTGSDNRIATWKIGDTATKPIVTGIPRGSQFHHGGRIKFGPDGFLYAGTG
                     DGQNGSNAQNKNSLGGKVLRMTKDGKPAPGNPFNSLVYSYGHRNVQGLTWLGSQLYVSD
                     IGASKVDELNKIDAGKNYGWPTCEGSCGTAGMTNPVKQWPTSQATPSGLTTYKGHFYMA
                     SLKGGTFKLTPNGAGGKIYTNLGRTRDEVAGPDGSLWVITPGGIHIADGN"
     gene            9614..9907
                     /gene="pqqA"
                     /locus_tag="C8D87_RS47980"
     CDS             9614..9907
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: protein motif:HMM:NF019654.4"
                     /locus_tag="C8D87_RS47980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_233442304.1"
                     /transl_table=11
                     /translation="MSASTNRVTHPMTLGNFMYGLDLDRRDDITCGSPPRPTEVPRAQQ
                     SGTPAGDPRSCAMNVVVNTAEQKLPEVKREWVKPDFRDFETPMEVTAYAARS"
     misc_feature    9653..9655
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..10696
                     /gene="pqqC"
                     /locus_tag="C8D87_RS27080"
                     /old_locus_tag="C8D87_106304"
     CDS             10001..10696
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005464293.1"
                     /locus_tag="C8D87_RS27080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106304"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_112228847.1"
                     /sec_met_domain="TIGR02111 (E-value: 1.7e-84, bitscore:
                     278.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVPPEEFVAELRALAPRYWDSHPFHLRMHAGQLSKHELQAWAA
                     NRWYYQRCIAQKDAAILSNCPIPDIRRQWRERIIWHDGTQPGEGGAENWIRLAEAVGLT
                     REEVLDERHVLPGTRFAVDAYVNFARTKPWVEAIASGLTEMFSGALMRKRLAALREQYP
                     WIAEEGFAYFTNRIQAVAGEGQATLDIVVEHSCTRAQQEAAIAALSFKCDVLRAVLDTV
                     DYYSGKGKP"
     gene            10693..10971
                     /gene="pqqD"
                     /locus_tag="C8D87_RS27085"
                     /old_locus_tag="C8D87_106305"
     CDS             10693..10971
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098207.1"
                     /locus_tag="C8D87_RS27085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106305"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_233439203.1"
                     /sec_met_domain="PqqD_RRE (E-value: 3.4e-20, bitscore:
                     66.9, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.3e-12, bitscore: 40.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSVVALDAVPRIRRGVKCTYDQIREAHVVLFPEGVLVLNETAAS
                     VVSLCDGVRSVGDIALALGDVYAGVQPEDIAELVARLVERRVVDVDG"
     aSDomain        10702..10959
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C8D87_RS27085_PqqD_RRE.1"
                     /evalue="1.50E-21"
                     /identifier="RREFam006.1"
                     /label="C8D87_RS27085"
                     /locus_tag="C8D87_RS27085"
                     /protein_end="89"
                     /protein_start="3"
                     /score="66.9"
                     /tool="antismash"
                     /translation="VVALDAVPRIRRGVKCTYDQIREAHVVLFPEGVLVLNETAASVVS
                     LCDGVRSVGDIALALGDVYAGVQPEDIAELVARLVERRVVD"
     gene            10964..12043
                     /gene="pqqE"
                     /locus_tag="C8D87_RS27090"
                     /old_locus_tag="C8D87_106306"
     CDS             10964..12043
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098206.1"
                     /locus_tag="C8D87_RS27090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106306"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_112228848.1"
                     /sec_met_domain="PTHR43273 (E-value: 3.5e-34, bitscore:
                     113.6, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6.3e-25, bitscore: 83.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.3e-06, bitscore: 22.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 7.9e-14, bitscore: 47.2,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.1e-13, bitscore:
                     45.2, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEAPFGLLAELTHRCPLQCGYCSNPVELVRRNAELDTESWRRVF
                     DQARSLGALQVHLSGGEPLLRPDLPELVAHANSLGCYVNLVTSGVGLSRERLRELASRG
                     VDHVQLSLQDATKAGNDRIAGIKAFDRKVEAAAYIREEGLPLTVNTVLHRQNLDNIAGI
                     IAMAEEMGAERLELANTQYYGWALRNRAVLLPTREQLAVADPIVAAAQERLRGRMEIVY
                     VIADYHEAHPKPCMYGWGARQLTVAPDGDVLPCPAATVISSLQIENVRDSSLHDIWHNS
                     PSFNAFRGYEWMKDPCRSCPRKEIDFGGCRCQAFQLTGDAANTDPVCSLSPDRSTVDLI
                     LAKEMAPSEVPAMAMRKMS"
     gene            12040..12921
                     /gene="pqqB"
                     /locus_tag="C8D87_RS27095"
                     /old_locus_tag="C8D87_106307"
     CDS             12040..12921
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631257.1"
                     /locus_tag="C8D87_RS27095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106307"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_112228849.1"
                     /transl_table=11
                     /translation="MKAVLLGTTAGGGFPQWNCACALCVRARSGELPSRSQDCLVISGD
                     GTNWWLVNASPDIRTQIAACSPLNPGPGPRDTPIRGALFTDAELDHTLGLLTLRGGAGL
                     TVWAPGPVLHALRDQFDLRTVIDGYAPVAWRQVEADQPLDLGGLLVSAIPISGKRPKYA
                     RSSTVDGHWVVAYRFEDPISGGVLVYAPCLASWPAGFDDVVAEADCLLLDGTFYAASEM
                     GSATGSSSGQAAMGHLPITHSLPELRRFPAVRRIYTHLNNTNPVLDPESPEAAKLREAG
                     VEVPLDGTVIEL"
     misc_feature    12964..12978
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.9"
                     /tool="antismash"
     gene            13065..13889
                     /locus_tag="C8D87_RS27100"
                     /old_locus_tag="C8D87_106308"
     CDS             13065..13889
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004562867.1"
                     /locus_tag="C8D87_RS27100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106308"
                     /product="hypothetical protein"
                     /protein_id="WP_112228850.1"
                     /transl_table=11
                     /translation="MSGYLELVFSTALYGLGIVAQTVAAQRADVRPGTGLGLLARLAKD
                     RLYLFGFAGQVGGFGFAFLARAELPLYLVQAGSSCAVGLATAFGLLVLKWRVRPLEIAV
                     LVMMAIGLVLLVTASESSVAKDIPTVPGLVLLGLPLLVIVFCSRAAQGSNSVIVSVLAG
                     TAFAVVAIIGRSVADESPADMLLNPLTWLMIVAALVGQSCLAVALQRGTATSSVAATDA
                     TTVVLTSVIGLGMLGDRITPGWEWAVGFGMTLVVAGVLVLGSPNRTTAEVAG"
     gene            13886..14827
                     /locus_tag="C8D87_RS27105"
                     /old_locus_tag="C8D87_106309"
     CDS             13886..14827
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229150.1"
                     /locus_tag="C8D87_RS27105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106309"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_112228851.1"
                     /transl_table=11
                     /translation="MRPASVSLDLDNLWAYLKTHGNPDWESRPSFLATAVPRLLDVFGE
                     HRLTTTVFVVGADAERDDGAQAVRDIVAAGHEVANHSWGHEPWLHRYSRPELEAELVRA
                     EDAITAAGAPRPVGFRGPGYSVTPALLEILAARGYRYDASTLPTWIGPLARAYHNRTAR
                     DRAEGASDLFGGFGKVLAPNTPFRWHGTGLVELPVTTMPLLRVPIHGAYLLQLHQISPR
                     LARGYFRAALRLCLLTGTAPSLLLHPTDVLSGAEAPGMEFFPGMAVPGAEKAALLGWVL
                     SSLRENFDVAGAGAHVDRLSELLRERRTELCG"
     gene            14824..15987
                     /locus_tag="C8D87_RS27110"
                     /old_locus_tag="C8D87_106310"
     CDS             14824..15987
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103312.1"
                     /locus_tag="C8D87_RS27110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106310"
                     /product="O-antigen ligase family protein"
                     /protein_id="WP_112228852.1"
                     /sec_met_domain="Wzy_C (E-value: 4.6e-16, bitscore: 54.5,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLLRVLACATVLLAPLEGYLQEVHPHLAKVVPALLIMSWVAQR
                     VRERRLPAPHPLHALLALFAVVLLASSAVHAADPFTADYTQRFLPFLVITAVLADVVAR
                     EVPVRAVLLAAVGGAVSAAVGALYSLVVDGEARATGPLEDPNDLAYYLVVALPLLIALP
                     ARRFLLPVGAILAAGAAATFSRGGGLALAFAAVWLVARRGVSMRAVTATVGGLAVIGLG
                     AVVFAGPVLERALAEKTYIAATNVDTRELRWQAAARMLADNPVLGVGPGGFRSEYPAAS
                     RNAEIDEQSPVAHNIYLEIGAELGLPGLACFLGAVALAFVATERVLRARADRSMLAVQA
                     SLIAALVAATFLSEQYYLPIWSLVAVAIAADLRREESERDACAARHQ"
     gene            15962..17023
                     /locus_tag="C8D87_RS27115"
                     /old_locus_tag="C8D87_106311"
     CDS             15962..17023
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640643.1"
                     /locus_tag="C8D87_RS27115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106311"
                     /product="glycosyltransferase"
                     /protein_id="WP_112229052.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 6.9e-33,
                     bitscore: 108.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLHVISEMGAGGAEAVVAGMVRAGGDFGWESGVASGGGHRAEA
                     LRAQGFSTFDVPVPRRRVSGVLRAVSAVRSAVRSFGPDVVLAHNVSASLVARMAAGGRP
                     VATVFHGVSESDLGGAARILRRTSRAVVAVAEASADRLRALGVDVEVIPNAVFAEPPRV
                     DRASIRGVLGIGPDVPVALCPARLEPQKRHDVLLEAWAMVAGAILLLAGDGSLRADLER
                     RAEELGVGDRVRFLGTRCDVPDLLEATDVVVLTSDWEGMPIAVLESLAAGRPVVASDVD
                     GVREALSGGGGVLVPRRSPSATATALASFLFDARECAAAGAAGRAAVERDHDPHTFMKS
                     YDEMLRTIGGERR"
     gene            17020..17889
                     /locus_tag="C8D87_RS27120"
                     /old_locus_tag="C8D87_106312"
     CDS             17020..17889
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640644.1"
                     /locus_tag="C8D87_RS27120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106312"
                     /product="hypothetical protein"
                     /protein_id="WP_112228853.1"
                     /transl_table=11
                     /translation="MNKRTLLEATAVALVVAVLVLAVTSLRGEQYESRISVLAVPVTQT
                     DSAAQYGEVASLAMPAIVQMVHSPTVLEAAARAASTTPREIADGVGVELVPASGLARLS
                     VRAGSDEQAGAAVTAVAKAVADANLLAPAGRLRLLDERPETTRVAPDWKLAAGLALAAA
                     LAAGIATAALRALRRPRTGEAAVRAAVATAGVRHPVALVREDDPEMLDRLTALCVAAAR
                     PVRVIPADHGLTAQAESLAESLPDKAAEPGEGTAVIAVADGEGEPGDLAAALAVLPASA
                     VLVAVVLT"
     gene            17886..19124
                     /locus_tag="C8D87_RS27125"
                     /old_locus_tag="C8D87_106313"
     CDS             17886..19124
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640645.1"
                     /locus_tag="C8D87_RS27125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106313"
                     /product="glycosyltransferase family 87 protein"
                     /protein_id="WP_215732503.1"
                     /transl_table=11
                     /translation="MITTTKPDTRTLITIAVAVIGALSAARALRPSWEVPAPTGENLAE
                     ERLQDFRDALYFPIREFLAGGNPYDPAAMFEHWPVRQNFNLYQPYHLVLHLPFALPEYR
                     IGAIAFTLASLVLLGVLGLLAARQAKLPLVLGTVVIGALLVTSQVGKAQLYVGQVNPLI
                     AVGAAAALLARSSHPRVAALGLAVAWLKPQFGLPLAILLFARGSRRVALGGTVIAALAS
                     LPVVGLLVYRGGGVGPFLDVISVNLAHASGTSYGAVDSVTAQRVDLPAVFFRVTDWLPP
                     AAELTALVGVLAATAYLARKLDRGDSDSRSVADLITAVGAVVAVVHQPGDVLIAVPAMA
                     AVAVVCWRRRKERDWRITGFAVVALLVPFAHLYFVNSAIIGLFGRRVDVTVDGVAIVVA
                     WVLLVVVAARKRA"
     gene            19121..20533
                     /locus_tag="C8D87_RS27130"
                     /old_locus_tag="C8D87_106314"
     CDS             19121..20533
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229155.1"
                     /locus_tag="C8D87_RS27130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106314"
                     /product="oligosaccharide flippase family protein"
                     /protein_id="WP_233442305.1"
                     /sec_met_domain="Polysacc_synt (E-value: 1.5e-20, bitscore:
                     69.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNRVGERAVRGSLWLFAVNVVSKGCQVAVTLVLAALLTEDGLGA
                     VSLVVSLVNIGQVVQSAGVYDVISRTNLDPGRLAGTVLTLSASGGLVLTVVLLLAAEPL
                     AAALGAPATLIRIAALSLPFTAIGGVQMALMHRDLDFRRRMLPDAGGMVLGAAVTIVLA
                     ALGFGPLAMAVGLLCTAVAQPVLAVVAGARVRPRWDRAAAGEALRWTAVVGPGAVVATL
                     LINVDYLTIGHVLGPSAVGVYSLAFRIAWMPYILVAVVLGGVMFPVCAELVRSGRTGDV
                     PGAVLRFTKATLMITGGFFVVIALLADQVVLFGERWAPAAPVLVALCAYGLGLGLLHTW
                     YQVIRAAGHARWYLALEVTHLVALLSALAVTTRHGVLAVAIAQAVIVWLLVPLTWWVLV
                     RHGLAFPAAALGRTVAGLLTACASCALVARLLPDTNGIAGALLAGLVLFGVYAAISLPL
                     NREAVRELRGTL"
     gene            20545..21600
                     /locus_tag="C8D87_RS27135"
                     /old_locus_tag="C8D87_106315"
     CDS             20545..21600
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103317.1"
                     /locus_tag="C8D87_RS27135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_106315"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_233442306.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 3.6e-29,
                     bitscore: 96.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPVEAGVAKVVLDLAEAQRAAGWDVHVVCPPHGWLPTRIPTHP
                     WHATRSPGPASLLETLRLRKVLRDLRPDVIHLHSSKAGLTGRLAVRGRTTTIFQPHLWS
                     FRLAGGLLRRMCVRWEAFASRWTHQLVCVSDDELATGRAAGVTAPAEVVCNGIDTTRLR
                     PADRSAARRRLGLPERPTAVCVGRLAPQKGQDLLLAAWPDVLADVPHAQLVLVGDGPMR
                     TAWQNGQESVLWWGHSDNVEDFYAAADVVVLPSRAEGMALVPLEAMACGRSVVAFDVDG
                     VRQSLGSAGAVVPGEDTAALGQALATRLADPSLAHREGHAGRRRAEMLFDRARMTDQII
                     TLVEKLEGDAR"
ORIGIN
        1 cggttcgccg tgctcggcga ctcgatggcg gtgggtgtcg gtgtgacgca tccctcgcag
       61 atgccgggcg tgctgctggc ccaggcgctg gccgaggagg cgggacggcc ggtgcggctc
      121 tcgacctgcg ccgtcagcgg ctcgacgacg cgggacctgg tgccgcaggt cgacgcggcc
      181 gtccgggacg caccgcaggt cgcgctgatc atcatcggtg cgaacgacgt cacctcccgg
      241 ctgggcgtcg gcgagtcggc gcggctgctg ggcgagcagg tccgcaagct gcgcgccgcc
      301 ggctgcggtg tcgtcgtcgg cacctgcccc gatctcggga tcgtgcggcc gattccgcaa
      361 ccgttgcgct acgtcgggca caggtacagc ctgcggctgg cggaggcgca gaccgcggag
      421 gtgtcgcggg cgggtggagt gccggtgtcg ctcgcgaacc tgctggcgcc cgagttcatg
      481 gcgcgccacg tcgacatgtt cagctccgac cgctttcacc ccagcgccgt cggctacgag
      541 gccgcggccg gcgtgctgct ggcgccgttg tgccaggtgg cggggttgtg gccgggttgg
      601 cgcacgcccg cgttgccgag gcggtctgcg gcggctctcg cgctgcggcc gtcccgcgtg
      661 cctgggtggc tgcaaaggcg gcacgcctga gtttcgaaat tcgcgtcacg tgcgctggcc
      721 tgggtgagcg ggcgttaact acgctcgacc gcgaccttga ctctcaacga ggagtttcgt
      781 gatgcctgag gccgtgatcg tctccgccgc ccgctccccc atcggccgcg cgggcaaggg
      841 ttcgctgaag gacgtgcggc cggacgacct ggccgcgcag atggtgcgag cagcgctcga
      901 caaggtcccg cagctcgacc ccgcacagat cgacgacctg atgctcggct gcggcctgcc
      961 cggcggcgag cagggcttca acatggcgcg cgtggtggcc gtcctgctcg ggcaggactc
     1021 gctgcccggc acgaccgtca cgcggtactg cgcctcgtcg ttgcagacca cgcgcatggc
     1081 cctgcacgcc atcaaggcgg gcgagggcga cgtgttcatc tcggccggcg tcgagacggt
     1141 gtcgcggttc gcgaagggca gctccgactc gtggccggac acccacaacc cgctgttcgc
     1201 cgacgccgag gcccggaccg tttcggtggc ccagtccggt gcggacgagt gggtggaccc
     1261 gcgttcgctg ggcgtcgtgc cggacatcta catcccgatg ggccagaccg ccgagaacct
     1321 ggcgctgctg aagggcgtct cgcggcagga gatggacgag ttcggcgtcc gctcgcagaa
     1381 cctcgccgag aaggcgatcg cggacggctt ctgggcccgc gagatcactc cggtgacgct
     1441 gcccgacggc accgtggtct ccgcggacga cggcccgcgc gcgggcgtga cgtacgaggc
     1501 ggtttctgct ctgaagccgg tcttccgccc cgacggccgg atcaacgccg gcaactgctg
     1561 cccgttgaac gacggcgccg cggctctcgt gatcatgtcc gacacgaagg cgcgcgagct
     1621 cggcatcacc ccgctcgcca ggatcgtgtc gacgggcgtc tccggcctgt cgccggagat
     1681 catgggtctc ggcccggtcg aggcctcgaa gcgcgcgctg gcactggccg gattgtcgat
     1741 ctccgacatc gacctcgtgg agatcaacga ggcgttcgcg gcccaggtga ttccttcgta
     1801 ccaggacctc ggaatcgatt tggaccggct gaacgtgaac ggtggcgcca tcgccgtcgg
     1861 tcacccgttc ggcatgaccg gtgcgcgcat caccacgacc ctgatcaatt ccctgcagtt
     1921 ccacgacaag cagttcggtc tcgagaccat gtgcgtcggc ggtggtcagg gcatggcgat
     1981 ggtcatcgaa cgcctgagct gagatcccca agatctgcaa attgacgctt gcaagtagct
     2041 ccgcttcacc cgaacggagc tacttgcctg ccacctttct gccgatgacg taattcgtcg
     2101 cgtaacggcg tcatcaggcg agggggagtc cgtccctacc gcgatgagca aggagggtcg
     2161 gacatgccgt acgtgtggtg gcaaagcgaa tacgacctgc aatgccatgc cttctccctc
     2221 gaccaagcca acggttcccg cagcttttac gaggccgtct gcgaacactc ggtacccgat
     2281 gagcgggtgt cgcgtgccca ggcgggtgcc ctctgcacga cctgcctgat caaggtgggc
     2341 acgcaactgc ccgatgtccg ctggcgggcc tagacccgtc tcatgccgac cgacgccggt
     2401 gcgctctcgg tgaagccgtg ccgttcgtag agacgacggc cgggcgggtc ggcgagcagg
     2461 ttgacgtacg cgttcggcgc gtgttcgccg atgcggtcca gcagcgctgt catgatcgcg
     2521 tcgccgatgc ccttgcgctg atggtgcggc aacaccgcca tgtcgatgat gtggaagtac
     2581 cagccgccgt cgctgagcac gcggcccatg cccacggtct cgcctgactc cacgtggacg
     2641 acgtgtgcgc tggcccaggc gccgttgatg ccgttctcgg cttcttcgac ggtgcgcgcg
     2701 ctgaggcctg attccttgcg caggcgcagg tagtcgtcga ccgcgggcgg tgtcatctcc
     2761 agccggtacg cgtgatccac ggatctcccc caggtgtgct tgttcgaccg gtggcggtag
     2821 agcgccgtcc gagcttcctt ggtgcccagc ttctcgaggc cccagatcgc ccagtccccg
     2881 aagcgctcgt cgtcgaggtg agcgacgaag agcggcaacg ccctgggatc cccggcttcg
     2941 ccgatcagct ccagcaacca ggcgcgcagg ccctggtcgt cctcctcgcg gtggaactcc
     3001 tcgatgagct cgtcgaggtg ctccgccgcg tggggcttca gcatggcgaa gccggtttcg
     3061 cagtcctggc cgttgcggcg gcgcatcagc cgcatcgcct ctccgaacct cttgctcatt
     3121 ccacccccga acgccggagg gcgccccgcc gaagcgaagc gccctccgga aacccccgcg
     3181 gacgtcagtc cgagttgaag tacgacagca ggcgcaggat ctcggtgtac agccacacca
     3241 gggtgaccgt gagaccgaac gcgatctgcc acgcgaactt ggccggcaca ccggcccgga
     3301 tcgcctggtc ggcggcgtcg aagtcgatca ggaagctgaa cgccgcgaga ccgatgcaga
     3361 cgaggctgaa gatgatcgcg agcgcgccgc cgttgcggag gccgaggccg ccgtcggtga
     3421 agaagctcat gatcaggttg aagagcatga ggacggcgac gccgatgatc gcgccggtga
     3481 tccacttggt gaacttcggc gtgactcgga tcgcacccgt cttgtagacg atcagcatgc
     3541 cggcgaagac gccgatcgtg ccgatgatcg cctggccgat cacgacgaca ccctgacccg
     3601 gaccggtcca gcggtcgatc atggcgccga tgatgccgct gaaggcaccg aggaagatgc
     3661 cctcgacggc cgcgtaggcg atgacgagcg gcgggctcgg catgcgcttg aacatgatga
     3721 tcagcgcgag cacgaggccg atgatcgcgg ccgggaacag aaggttccac cactgcatca
     3781 cgtacgtgac gacggcggtc gcggccacca cggcgagcgt gatgccggtc ttcgtgacga
     3841 cgtcgtcgat cgtcatgggc cgctcgctgg tcagcggcgg cggagcctgc tggtagccgg
     3901 cctctggctg gccgaagcct gcatagcctc cgtacccgcc gccggtcggc aggttacgga
     3961 aagccgggtt gctgctggag cgcacctggt cctcctgggg cgttgcttta cgccgtcacg
     4021 ggtacaacga gcacgctggg tgccaggttc cccgtcggta aaggagactt tacccctgac
     4081 gacgatcaca cgtgcgcaaa tactgcgcta actccggagc gtagtgagac tacggcgtgt
     4141 cgcggcgtgt cattcctgaa gcgagtaagg cgcgtcacat ttcaatcaca ttcacacgga
     4201 cggtgacgac acacttcccc ctcgtggcgg cttgtacccg gtgtggggta ccgccaggct
     4261 cgcacgcgga attaccacag gtcagagggg accaagatcc aaaatgggct ggaaacgtct
     4321 tgccgccgtg gcggtggtct cgggtctcgc actcctgacc gcacccacga cggcgacagc
     4381 agtcggcgtc aagggcatcg gccacaacgc gtcagggctc cagcccaacg ccacaccggg
     4441 cagcgagtgg cacgggtcct acgtctggca gaacaagcac gtgtggtgcg tgcagtacgc
     4501 gctgcccgcg ccggacagca acgtcggcta caaggaaggt gacgagctgc tgacgaaggc
     4561 gggcaagaag ctcccgtccg acgtcgcggc gaacatctcc tacctcctgc tgcgctactc
     4621 caccacgaag tccgcggaag aggcggccgc gctcgcgcac ctcctccaca cctggacctc
     4681 tcctgtcgac ggcaacgtga acctcggcgc gaccgacccc aagtacctcg cctacgacag
     4741 cgcgttctac gcctcgaagc tgccgcccgc cgtcatggac accgtcgcgc gcctcaaggc
     4801 cgacgccgag gccaaccgcg gcccgtggac gctcagcgcc accgccccca aggaaccgct
     4861 gatcatcggc accgagtcga gctggaccgt gtcgctggtc aaggcgaacg gccagggcgt
     4921 gcccagcgcg ccgatcgact tcacgctgac cgacgcgacg ctcgtcgacg gcagtgtcgg
     4981 cggcaaggcc accacgggcg ccgacggcag cccggccacg atcaagatcc tccccacggg
     5041 cccgaagccc tcgatcgcgg ccaacgcgga ctcccccgcc gacaagccgg tcgtgcacca
     5101 gccgatctcg acggacaaca tgcagcgcat ggtcaccaca ggcggcgaga agaagctgag
     5161 cgcgaacgcc accggacagg ccaagaccgc gcccggcaag gtgaagatca cgaagatcga
     5221 ctcggagacc aagaaggcca tcgcgggcgt cgccctgcgc gtcacgtcca aggaccagac
     5281 gaagcccgcg ctcaagcagg acgacaccga gctggtcggc accgacggca agccgctggt
     5341 gctgcagacc ggcgccgacg gcacggtcga ggtcccggac ctgcgcaccc cgcaggagat
     5401 ctgcctcgtc gaggtggcgg cgccgaaggg gtacgaggag ttcttcgacc cgaaggcacc
     5461 accggcctcg tgcggcacgc tcgcggcagg acagacgctc gcgctcgaac tggtgaacaa
     5521 gcccaacaag cccgtcgtgc ccagcacgat cccggccggt caggacggca agacgcccgt
     5581 cgcgaccgcg tcgttcgaaa cgcagctgcg tccgggtgtg atgctcgcgg tgggtggcct
     5641 cgtgctgctc ggtgcggcgc tggcaggctt cctggtgtgg cgcaggcagt gagtcccaag
     5701 gcgtttctga ccggcgcgct ggtggcgggt gttgccgcca ccagcgtgct ggtcaccgcg
     5761 tccgggaccg aggtgctcaa ggggcacgcg gtcgcggacg agatccccgt ggtcgggccg
     5821 gggccggtcg ctgacagcct cagcaccggc cgcggggccg acctcaccgg gctggtcggt
     5881 ggcgcgaaca cggccaacgc caagcccgcg gagcccacgc aaccacaacc cgcgccgccc
     5941 aaggccggtc ccggctcggt ccggctgcct tcgggaggca cggccacgct ggtccgccgc
     6001 gaggtgaagg acggcgtgct gcccgttccc gacggcatcg gcgaggccac ctggtggggt
     6061 gccgagctcg cggcgcagga aggcgcgacg gtcctcgccg ggcacgtcga ctggaagggc
     6121 gccagaggtc ccttcgccga gctgtggcag gcccagaacg gccgtgaggt cgtgatcgcc
     6181 gacagtgccg gcaaggagtt caagttccgc atcaaccaga tcgagacggt gcgcaaggaa
     6241 gaactgcctg cccgcgccgt cgagttcttc ggcccgcgcg ggccgcaccg gttggtgctg
     6301 gtcacctgcg gcggcacgtg gatcggcggc cagcagggtt acgaagccaa ccgcgtggtg
     6361 atcgccgaac ccgttgcgta atgaagcaac cccttcgggt gaccagtcgt ctccataagt
     6421 gtgaaacggt ggggatggtt gaccacgggc ctggcgcttg cgctggccct cgtgctggtg
     6481 atgactctcg gcccgaccaa ggaccagcag agccaggcgg acgccggtcc cctgccgatg
     6541 gcacctcggc tgcccgcccc caaggacgcc ggccccacgc cgacagttcc cgcgccgagc
     6601 cccgaacaac tgcagcagca gccgtggatg cacaagctcg cacccggtga gaagccaccg
     6661 cagttcgtgc tgttctcctt cgacggggcg gtctccaagc agcactggga caaggtcctg
     6721 ccgatcgcca gggagaagaa ggcgcacgtc accggtctgc tgtccggcgt gtacatgctg
     6781 gccgaccagg acaagatgca gtaccagccg cccgcgggac tcaagcgcgg cgtctccgac
     6841 atctccttcg gtggcagcaa acaggacatc gccgcccgca tcggctacct caaccaggtg
     6901 atcgacgagg gccacgagat cggcacgcac tacaacggcc acttctgctc cggcggcacc
     6961 cagccgtcgg tcgacaagtg ggacagcaag gcgtggaacg aggagctcgc ccagttcaag
     7021 cagatcgtgg acagggcacg tgccgccggc ttcaagctcg ccgacggcgc tgtccggggt
     7081 ggacggacgc cgtgcctgga aggcaactgg gaccaagctt tccccgcgat ggcggccaac
     7141 ggcctggtct acgacaccag caaggtcgcg ctgggcgtgc agtggccgtc cgtccaaaac
     7201 ggactgtacg agttcccgat gcccgaggtg agggttcccg cgctgggcag gcaggtcgtc
     7261 atgatggact tcaacctctg gtacgcgctc aacgccgcca gggacgaacc ccaccgcgcg
     7321 accgagttcg cccagatcgt cttcgacacg tacaagtcgg tgcaccaggc cgcgttgaac
     7381 ggcaaccgcg cgccgctcgt gatcggcaac cacttcaacg agtggaacgg ttcggcgttc
     7441 tcgaacgcga tggagcagtt cctcgcgtac gtgtgcgaca agccggaaac ggtgtgcgcc
     7501 acctacaccg aggtgatcca gtggatgcag ctgcaggaac cggcggtgct ggaccagctc
     7561 cgccggatgc ccgcggctcg caactagacc ctcgctcagc cgtccgtcaa gacgatccgg
     7621 tcgtcgttcg cacccggctg gccgttgttg tcctggttgg acgttcccag ccactacgtg
     7681 ccgtccggcg ccggagccac cgcccgtacg cggccgtagc tcgtgaacac cgcctgcggg
     7741 gtgccgagcg tggtgccgtt caccgggatc ttccacacgc gcctgtcggt gaccggaccg
     7801 acgtacaacg cgttcttgca gtagccgatg ccggccggac cggcctggct ggtgggccac
     7861 gtcttcaccg ggttggtcat ccccgcggtg ttgcagttgc cctcacaggt cggccagcgg
     7921 tagttcttgc cagccgcggg cctgcccgcg gagtcgaagc ggagaacctt gccgcccgac
     7981 gagttccagt tctgcgccgt gctggtgtgc tggccgtcac ccgtggtcgc ccacaggaag
     8041 ccgtccgggc cgaactccag gccgccgccg ttgtggtagc ggcatcttgg ggatgccgct
     8101 cacgatcacg tgcggtgtac cgccgagccg cagcttcgtg acgcggttgt cgcttgccgt
     8161 ggagtagcag atgatgccgc tgccgtccgg caagaactcg atgtcccacg ggatgtccag
     8221 cttcgtggtg attgtccgtt cggcgagaac cgacgggccg tcctgcgcgg aggccgggat
     8281 gacgcagagg gatgcgccac ggcagtgcag gttgccgcca ccgcgatacg acgagcacgc
     8341 aggtgctctc cttcatgtcc gctcgtgttt gtctgcggcg gcggcgttgc agggcgtagt
     8401 tgcccaatca caagccggat aaacccacaa cggtcatcgg atgtgtggga cgtccctcgc
     8461 ctccgagcgg gtgaggcgag ggacgttctc aactacctcg ggtagtcgag tccggtgtgg
     8521 tcagttgccg tcggcgatgt ggatcccgcc aggggtgatc acccagagcg agccgtcggg
     8581 acccgcgacc tcgtcccgcg tgcgcccgag gttggtgtag atcttgccgc cggcaccgtt
     8641 cggcgtgagc ttgaacgtgc cgcccttgag ggaggccatg tagaagtggc ccttgtaggt
     8701 ggtgaggccg gacggcgtcg cctgcgaggt cggccactgc ttcaccgggt tggtcatccc
     8761 ggcggtgccg cacgaaccct cgcaggtcgg ccagccgtag ttcttgccgg cgtcgatctt
     8821 gttgagctcg tcgaccttgc tggcgccgat gtcggagacg tagagctggc tgcccagcca
     8881 ggtcaggccc tgcacgttgc ggtggccgta ggagtagacg agcgagttga acgggttgcc
     8941 cggcgcgggc ttgccgtcct tggtcatgcg caggaccttg ccgcccaagg agttcttgtt
     9001 ctgcgcgttg ctcccgttct ggccgtcacc ggtaccggcg tagaggaagc cgtcgggacc
     9061 gaacttgatg cggccgccgt ggtggaactg cgagccgcgc ggaatgccgg tgacgatggg
     9121 cttcgtggcc gtgtcaccga tcttccacgt ggcgatccgg ttgtcgcttc cggtggtgta
     9181 gtagaggaag agcgtcttgt ccgcggcgta cgtcggcgac accgcgatgc ccagcaggcc
     9241 cgcttccttc gtcaccgaga caccggggat gtcaccgact ttcgtgactt tgccgtcctt
     9301 ggtgatggtg gagacggtct tggcgtcctt ctgcgtgaag atgccggtgc cgtccggcag
     9361 gaagtcgatg ctccaggcct gcttgaggcc ggtggcgatc gttttgacgg ccatcgtgcc
     9421 gacttcgccg ctctctgccg cggacgccag cgggctgctg gacagtccga ccgcaagtgc
     9481 gaggacgccg gcgtacgcac ttcgacgagc acccattgtg ctgacccctc aactttcgcg
     9541 tcgtgcggcg acggcgagcc cgcgtcggaa ggtgcgggct gggggcctcc cgatacaacc
     9601 acggtgtgta gtcatgagcg catccaccaa tcgggtcacc catccgatga ctttaggtaa
     9661 ctttatgtac ggtctggacc tcgaccgccg ggacgacata acgtgtggtt cgccgccgcg
     9721 ccccacggaa gtgccgcgcg cccagcaatc gggcacgccg gccggagacc cgaggagttg
     9781 cgccatgaac gttgtcgtca acactgccga gcagaagctt cccgaggtca agcgcgagtg
     9841 ggtcaagccc gacttccgcg acttcgagac gccgatggag gtcaccgcct acgcagcccg
     9901 cagctgacgt tgggcttctg ccggggttcc tgccgtttcg cgggcaggaa ccccggcccc
     9961 acgcctcgcc gcgcgtcccc cagccgagga gtatccgccc atgaccgctg tacctcccga
    10021 ggagttcgtc gccgagctcc gcgccctcgc gccccggtac tgggacagcc acccgttcca
    10081 cctgcgcatg cacgcgggtc agctgagcaa gcacgagctg caggcgtggg ccgcgaaccg
    10141 ctggtactac cagcgctgca tcgcgcagaa ggacgccgcg atcctttcca actgcccgat
    10201 accagacatc cgacgtcagt ggcgtgaacg gatcatctgg cacgacggca cgcagccggg
    10261 cgagggcggc gccgagaact ggatccgcct cgcggaagcc gtcgggctga cgcgggaaga
    10321 ggtgctcgac gaacggcacg tgctgcccgg taccaggttc gccgtcgacg cctacgtgaa
    10381 cttcgcgcgc accaagccgt gggtcgaggc catcgcctcc ggcctcacgg agatgttctc
    10441 gggtgccttg atgcgcaagc gtttggcggc attgcgggag cagtacccgt ggatcgccga
    10501 ggagggcttc gcctacttca ccaaccgcat ccaggcggtc gccggtgagg gacaggccac
    10561 tttggacatc gtggtcgagc actcctgtac tcgtgcccag caggaagcgg ccatcgccgc
    10621 gttgtcgttc aagtgcgacg tgctgcgtgc cgtgctggac accgtcgact actactcggg
    10681 caagggcaag ccgtgacgtc cgtcgtcgcc ctggacgccg tgccgcgcat ccggcgtggg
    10741 gtgaagtgca cctacgacca gatccgggaa gcgcacgtcg tcctgttccc cgaaggtgtg
    10801 ctggtgctga acgagaccgc cgcctccgtc gtgtcgttgt gcgacggggt ccggtcggtc
    10861 ggcgacatcg cgctggcgct aggggacgtg tacgcgggcg tgcagcccga ggacatcgcc
    10921 gagctcgtgg ccaggctggt ggaacggagg gtggtggacg tcgatggctg aggcaccttt
    10981 cggcctgctg gccgagctga cgcaccgatg cccgttgcag tgcggctact gctcgaaccc
    11041 cgtcgaactg gtccgccgca acgccgagct cgacaccgag tcgtggcgcc gggtcttcga
    11101 ccaggcgcgg tccttgggag cactgcaggt ccacctgtcc ggcggcgagc cgttgctccg
    11161 gccggacctg ccggagctgg tggcgcacgc gaacagcctc ggctgctacg tcaacctggt
    11221 cacgtccgga gtcggcctgt cccgggaacg gttgcgggag ctggcttctc gcggtgtcga
    11281 tcacgtgcag ctctccctgc aggacgcgac gaaggccggc aacgaccgga tcgcgggcat
    11341 caaggcgttc gaccggaagg tggaggcggc ggcgtacatc cgtgaggaag gcctgccact
    11401 caccgtcaac acggtgctgc accggcagaa cctcgacaac atcgccggaa tcatcgcgat
    11461 ggccgaggaa atgggcgccg aacgcctcga gctcgccaac acgcagtact acggctgggc
    11521 tctgcgcaac cgggcggttc tgctgcccac ccgcgaacag ctcgcggtgg ccgatccgat
    11581 cgtcgccgcg gcgcaggaac gtctgcgcgg gcggatggag atcgtctacg tcatcgccga
    11641 ctaccacgag gctcatccga agccctgcat gtacgggtgg ggcgcgcggc agctgacggt
    11701 ggcaccggac ggcgacgtgc tcccctgtcc cgccgccacg gtgatctcgt cgttgcagat
    11761 cgagaacgtg cgggactcgt cgttgcacga catctggcac aactccccgt ccttcaacgc
    11821 tttccgcggc tacgagtgga tgaaggaccc gtgccgctcg tgcccgcgca aggagatcga
    11881 cttcggcggg tgccggtgcc aggcgttcca gttgaccggt gatgccgcca acaccgaccc
    11941 ggtgtgctcg ctgtcccccg atcggtccac tgtggacctg atcctggcga aggagatggc
    12001 gccttccgag gttccggcca tggcgatgag gaagatgtct tgaaagcggt tctgctcggt
    12061 accacggccg gtggcggctt cccgcaatgg aactgcgcgt gcgctctgtg cgtgcgcgct
    12121 cgttccggtg agttgccgtc gcgttcgcag gactgcctgg tgatcagcgg cgacggcacc
    12181 aactggtggc tggtcaacgc ttctccggac atccgcacgc agatcgcggc ctgttcgccg
    12241 ctgaaccccg gccccggccc gcgtgacacc ccgatccgcg gtgccctgtt caccgacgcc
    12301 gagctggacc acacgctggg actgctgacg ttgcgcggcg gggccggcct gacggtgtgg
    12361 gcaccaggac cggtcctgca cgcgctgcgg gaccagttcg acctgcgcac ggtgatcgac
    12421 ggctacgcgc cggtggcgtg gcggcaggtc gaggcggacc agccgctcga cctcggtggg
    12481 ctgctggtct cggcgattcc gatcagcggc aagcgtccca aatacgcccg ttcctccacc
    12541 gtggacgggc attgggtggt cgcataccgc ttcgaggatc cgatttcggg tggcgtgctg
    12601 gtttacgcgc cttgcctggc gtcgtggccc gccggtttcg acgacgtcgt ggccgaggcc
    12661 gactgcctgc tgctcgacgg caccttctac gcggcgtccg agatgggctc ggccaccggc
    12721 agctcgtccg gtcaggccgc catgggccat ctgcccatca cacacagcct tcctgaactg
    12781 cgacgattcc ccgccgtccg gcgcatctac acccacctca acaacacgaa cccggtgctc
    12841 gacccggagt ctcccgaggc cgcgaagctg cgtgaggctg gcgtcgaggt gccactggac
    12901 ggcaccgtca tcgaactctg attcgtcacc ctttcgagca aatatcttcc actttcgagc
    12961 gattatcgtc tgccaattct cgcaatgagt tgtggcatat ccctctagtg gggaacgccc
    13021 tcgcggctcc gtattcttcg gagccttgac gagggaggtc ctgcatgtcc ggataccttg
    13081 agctcgtttt ctccaccgcg ctgtacggct tgggcatcgt ggcccagacc gttgccgcgc
    13141 aacgggcgga cgtcaggccg ggcaccgggc tgggactcct cgcccggctg gccaaggacc
    13201 gtctctacct gttcggtttc gcgggccagg tgggcggttt cgggttcgcg ttcctcgccc
    13261 gcgccgagct gccgctgtac ctggtgcagg cgggatcttc gtgcgccgtc gggctcgcga
    13321 ccgcgttcgg cctgctggtg ctgaagtggc gcgtgcggcc gctggagatc gcggtgctgg
    13381 tcatgatggc gatcgggctc gtcctgctgg tcacggcgtc ggaatcgtcg gtggcgaagg
    13441 acatccccac ggtgccggga ctggttctgc tcgggctgcc gttgctcgtg atcgtgttct
    13501 gctcacgagc cgcacagggt tcgaactccg tcatcgtctc ggtgctcgcc ggcaccgcct
    13561 tcgcggtcgt ggcgatcatc ggccggtcgg tcgcggacga gtcgccggcc gacatgctgc
    13621 tgaacccgct gacctggttg atgatcgtgg cggcgctggt gggccagtcc tgcctcgcgg
    13681 tcgcgttgca acgcggcacg gccacgtcgt cggtggcggc gacggacgcg acgaccgtgg
    13741 tgctcacctc ggtcatcggc ctcggcatgc tgggcgaccg gatcacgccg ggctgggagt
    13801 gggccgtcgg gttcggcatg acgctcgtcg tggccggcgt gctggtgctg ggctccccga
    13861 accgcaccac cgccgaggtg gccgggtgag gcccgcgagc gtctcgctgg acctggacaa
    13921 cctgtgggcc tacctcaaga cccacgggaa cccggactgg gagagcaggc cgagcttcct
    13981 cgccacagcc gtgccccggc tgctggacgt cttcggtgaa caccggctca ccaccacggt
    14041 tttcgtggtc ggggcggacg ccgaacgcga cgacggggcg caggccgtcc gcgacatcgt
    14101 ggcggcgggg cacgaggtgg ccaaccactc gtggggccac gaaccctggc tgcaccggta
    14161 ctcgcggccc gagctggagg cggagctcgt cagggcggag gacgcgatca cggccgcagg
    14221 cgctccccgg ccggtcgggt tccgcggtcc cggctacagc gtcaccccgg cactgctgga
    14281 gatcctggcc gcgcgcggct accgctacga cgcgagcacc ctgccgacgt ggatcggccc
    14341 gctggccagg gcgtaccaca accgcaccgc ccgcgaccgg gcggaaggtg ccagcgatct
    14401 cttcggcggc ttcggcaagg tgctggcacc gaacaccccg ttccgctggc acggcaccgg
    14461 tctggtcgag ctgccggtga ccaccatgcc gttgctgcgc gtgcccatcc acggcgcgta
    14521 cctgttgcag ctgcaccaga tctcgccacg gctggcacgc gggtacttcc gcgccgcact
    14581 gcggttgtgc ctgctgaccg gcacagcgcc gtcgttgctg ctgcacccga ccgacgtgct
    14641 gagcggcgcc gaggcgcccg ggatggagtt cttccccggc atggcggtgc cgggtgccga
    14701 gaaggccgcg ctgctcggct gggtgctttc gtcgctgcgc gagaacttcg acgtcgccgg
    14761 cgccggagcg cacgtcgacc ggctgtcgga gctgctccgg gagcgccgga cggagctgtg
    14821 cggatgacgt ggctgctgcg cgtgctcgcg tgcgcgacgg tcctgctggc cccgctggag
    14881 ggctacctgc aggaggtgca cccgcacctc gcgaaggtgg tgccggcgct gctgatcatg
    14941 tcctgggtcg cgcaacgggt gcgggagcgg cgtctgcccg cgccgcatcc gctgcatgcg
    15001 ttgctggcgc tgttcgccgt ggtgttgctg gcctcgtcgg ccgtgcacgc cgctgatccg
    15061 ttcacggcgg actacaccca gcgcttcctg ccgttcctgg tgatcaccgc ggtgctggcc
    15121 gacgtcgtgg cacgcgaagt gccggtgcgg gcggtgctct tggcggcggt gggcggtgcc
    15181 gtgagcgcgg cggtcggcgc gctgtacagc ctggtcgtcg acggtgaggc acgggcgacc
    15241 ggcccgctgg aggaccccaa cgacctcgcc tactacctgg tggtggcact tccgctgctg
    15301 atcgccctgc ccgccaggag gttcctgctg ccggtaggcg cgatcctcgc ggcgggcgcg
    15361 gcggcgacgt tctcccgcgg tggtggcctc gcactggcgt tcgccgccgt gtggctcgtg
    15421 gcgcggcgcg gcgtgtcgat gcgcgcggtc acggcgacgg tgggcgggct cgcggtcatc
    15481 gggctcggcg ccgtggtgtt cgcgggaccg gtgctggagc gggcgctcgc cgagaagacg
    15541 tacatcgcag cgaccaatgt ggacactcgt gagctgcgct ggcaggccgc cgcccgcatg
    15601 ctcgcggaca acccggtgct cggcgtcggg ccgggcgggt tccgcagcga gtacccggcg
    15661 gcctcgcgca acgccgagat cgacgagcag tcaccggtgg cgcacaacat ctacctggag
    15721 atcggcgcgg aactcggcct gcccggtctc gcctgcttcc tcggcgcggt cgcgctggcg
    15781 ttcgtggcga cggaacgcgt cctgcgtgca cgtgccgacc ggtcgatgct cgcggtccag
    15841 gcgtcgctga tcgccgcgct ggtcgcggcg acctttctgt ccgagcagta ctacctgccg
    15901 atctggtcgc tggtcgcggt ggcgatcgcg gccgacctgc gccgtgagga gagtgagcgc
    15961 gatgcgtgtg ctgcacgtca tcagtgagat gggcgccgga ggagccgagg ccgtcgtcgc
    16021 gggcatggtg cgggccggcg gcgacttcgg ctgggagtcg ggtgtcgcga gcggcggcgg
    16081 gcatcgtgcc gaggccttgc gggcgcaggg tttctcgacg ttcgacgtgc cggtgccgcg
    16141 gcgcagggtc tccggagtgc tgcgcgctgt ttccgctgtg cgttcggcgg tgcgatcctt
    16201 cggtcctgat gtggtgctgg cgcacaacgt gtccgcgagc ctcgtggcgc ggatggcggc
    16261 gggtggccgg ccggtggcga ccgtgttcca cggtgtctcc gagtcggatc tcggtggtgc
    16321 ggcacggatt ctccggcgta cctcacgtgc ggtggtcgcc gttgccgagg cgagcgctga
    16381 ccggttgcgt gcgctgggtg tggacgtcga ggtgatcccg aacgcggtgt tcgccgagcc
    16441 gccccgagtc gaccgggcct cgatccgcgg ggtgctcggc atcggtcccg acgtgccggt
    16501 ggcgttgtgc ccggcgcgcc tcgaacccca gaagcggcac gacgtgctgc tggaggcgtg
    16561 ggcgatggtc gcgggcgcga tcctgctgct ggcgggcgac ggcagcctgc gcgcggacct
    16621 ggagcggcgc gccgaggagc tcggtgtggg cgaccgcgtg cggttcctcg gcacccgttg
    16681 tgacgtcccg gatctgctgg aggccacgga cgtcgtggtg ctcaccagcg actgggaggg
    16741 catgccgatc gcggtgctgg agtcgctggc cgcaggccgc ccggtggtgg cgtccgatgt
    16801 ggacggtgtg cgcgaggcgt tgtccggtgg tggcggcgtg ctggtgcccc gccgctcccc
    16861 ctcggcgacc gcgaccgcgc tggcctcgtt cctgttcgac gcacgggagt gcgccgcggc
    16921 cggcgccgcg ggccgggccg ccgtcgagcg cgaccacgac ccgcacacct tcatgaagtc
    16981 ctacgacgaa atgctccgaa cgattggggg agaacgacgg tgaacaagcg cacgctgctg
    17041 gaggcgaccg cggtggcgct ggtcgtcgcg gtgctcgtgc tggcggtgac gtctctgcgg
    17101 ggcgagcagt acgagagccg gatctccgtg ctcgccgtgc cggtcacgca gaccgactcc
    17161 gctgcccagt acggcgaggt ggcctcgctc gcgatgcccg cgatcgtcca gatggtgcac
    17221 agcccgaccg tgctggaggc cgccgcgcgg gcagcgtcca ccacgccgcg cgagatcgcc
    17281 gacggcgtcg gtgtggagct ggttccggcg tccggactcg cccgcctgtc ggtgcgggcg
    17341 ggatcggacg agcaggccgg tgccgccgtg accgcggtgg cgaaggccgt ggcggacgcg
    17401 aacctgctcg ctccggccgg tcggttgcgc ctgctcgacg aacgcccgga aaccacgcgg
    17461 gtggcgccgg actggaagct cgcggcaggg ctcgccctgg ccgcggcgct ggctgcgggc
    17521 atcgcgacgg ccgccctgcg agcgttgcgc aggccccgca ccggggaggc cgcggtgcgg
    17581 gccgccgttg ccacggccgg ggtgcggcat cccgtggcgc tggtccgcga ggacgacccc
    17641 gagatgctcg accggctgac ggcgttgtgc gtcgcggcgg cccggccggt gcgggtgatt
    17701 cccgcggatc acggactgac cgcgcaggcc gagtcgctgg cggagtcgtt gccggacaag
    17761 gcggccgagc ccggtgaggg cacggcggtg atcgcggtcg cggacggcga gggcgaaccg
    17821 ggtgacctgg ccgcggctct cgcggtgctg ccggcgtccg cggtcctggt ggcggtggtg
    17881 ctgacgtgat caccacgacc aagcccgaca cccgcacgct catcaccatc gcggtcgccg
    17941 tcatcggcgc actcagcgcg gcacgagccc tgcgtccgtc gtgggaggtc ccggcaccga
    18001 ccggggagaa cctggccgag gaacggctgc aggacttccg cgacgcgctg tacttcccga
    18061 tccgggagtt cctggcgggc ggcaacccgt acgacccggc ggcgatgttc gagcactggc
    18121 cggtgcggca gaacttcaac ctctaccagc cgtaccacct ggtgctgcac ctgccgttcg
    18181 cgttgcccga gtaccggatc ggcgcgatcg cgttcaccct ggcgtctctg gtgctcctgg
    18241 gagttctcgg gctgctggcc gcgcggcagg ccaagctccc gctcgtgctg ggcaccgtcg
    18301 tgatcggggc gctgctggtg acgagccagg tgggcaaggc gcagctgtac gtggggcagg
    18361 tcaacccgtt gatcgcggtg ggtgcggcgg cggcgttgct ggccaggtcc agtcatccgc
    18421 gggtggcggc gctcgggctg gcggtggcgt ggctgaagcc gcagttcggc ttgccgctgg
    18481 cgattctgct gttcgcacgc ggatcgcggc gggtcgcgct cggcggcacg gtcatcgcgg
    18541 cgctcgcgag cctgcccgtg gtggggctgc tggtgtaccg gggcggaggc gtcgggccgt
    18601 tcctcgacgt gatctcggtg aatctcgcgc acgccagcgg taccagctat ggcgcggtgg
    18661 attccgtgac ggcgcagcgg gtggatcttc cggcggtgtt cttccgggtg acggactggc
    18721 tgccgccggc ggctgagctc accgcactgg tcggtgtgct ggcggcgacc gcgtacctcg
    18781 cgcggaagct cgaccgcggc gactccgaca gccggtcggt cgcggacctg atcaccgctg
    18841 tcggcgcggt cgtggcggtg gtgcaccagc cgggtgacgt gttgatcgcg gtgcccgcca
    18901 tggccgccgt cgcggtggtg tgctggcggc gcaggaagga acgggactgg cggatcaccg
    18961 gcttcgcggt ggtggcgctg ctggttccgt tcgcacacct gtacttcgtg aacagcgcga
    19021 tcatcgggct gttcggccgc cgggtggatg tgacggtgga cggcgtggcg atcgtcgtgg
    19081 cctgggtgct gctggtcgtc gtcgcggcca ggaaacgcgc gtgacgaacc gggtcggtga
    19141 gcgggcggta cggggatcgc tgtggctctt cgcggtcaac gtggtcagca agggctgtca
    19201 ggtcgcggtc acgctggtgc tcgcggccct gctcaccgag gacggtctgg gtgcggtgtc
    19261 gctcgtggtg tcgctggtca acatcggcca ggtcgtgcag tccgcgggcg tctacgacgt
    19321 gatcagccgg acgaacctgg atccgggacg actcgcgggc accgtgctga cgctgagcgc
    19381 gagcggtggc ctggtgctca ccgttgtgct gctcctcgcg gcggaaccac tcgccgccgc
    19441 gctcggggca cccgccacgc tcatccggat cgccgcgctc agcctgccgt tcacggcgat
    19501 cggtggcgtg cagatggcgc tgatgcaccg cgatctggac ttccggcgcc ggatgctgcc
    19561 ggacgcgggt gggatggtgc tgggtgccgc ggtcacgatc gtgctggcag cactcggctt
    19621 cggaccgctc gcgatggccg tcggactgct gtgcacggca gttgcccagc ccgtgctggc
    19681 ggtggtcgcg ggagctcggg tgcgtccgcg ctgggaccgt gccgccgccg gggaagcgtt
    19741 gcgctggacg gctgtcgtcg gccctggcgc cgtcgtcgcc acgttgctga tcaacgtgga
    19801 ctacctgacg atcgggcacg tgctcgggcc gtcggccgtc ggcgtgtact cgctcgcctt
    19861 ccggatcgcc tggatgccgt acatcctcgt ggccgtcgtg ctgggcggcg tgatgttccc
    19921 ggtgtgcgcc gagctggtcc gaagtggacg gaccggcgac gtgcccggcg ccgtgctgcg
    19981 gttcaccaag gccacactga tgatcaccgg cggcttcttc gtggtcatcg ctctgctcgc
    20041 cgaccaggtc gtgctgttcg gtgaacgctg ggctcccgcg gcaccggtgc tggtcgcgtt
    20101 gtgcgcctac ggactcggcc tcggcctgct gcacacctgg taccaggtga tccgggcagc
    20161 gggacacgcg cggtggtacc tcgcgctcga agtgacgcat ctggtggccc tgctgagtgc
    20221 cttggcggtc accacacggc acggcgtgct ggccgtggcg atcgcccagg ccgtcatcgt
    20281 ttggctgctc gtgcccctca cctggtgggt gctggtgcgg cacggcctcg cgttcccggc
    20341 ggccgcactg ggccgcaccg tcgccgggct gctcacggcc tgcgcgagct gcgcgctcgt
    20401 cgcccggctg ctgccggaca cgaacgggat cgccggcgcg ctgctcgccg gactggtgct
    20461 gttcggcgtc tacgcggcga tctcgttgcc gctcaaccgt gaagccgtcc gcgaactgcg
    20521 aggaaccctg tgaaggtcgt gcacgtgacg caaccggtcg aagcgggcgt cgcgaaggtc
    20581 gtgctcgatc tcgcggaggc gcaacgggcg gcaggctggg acgtgcacgt ggtgtgccct
    20641 ccgcacggct ggctccccac ccggatcccc acgcatccgt ggcacgcgac ccgctcccca
    20701 ggaccggcct cactgctcga aacgctgcgg ctgcgcaaag tgctccgcga cctgcgtcct
    20761 gacgtgatcc acctgcacag ctcgaaggcg gggctgaccg ggcgcctggc ggtgcgcggc
    20821 cggaccacga cgatcttcca gccgcacctg tggtcgttcc ggctcgcggg cggactgctg
    20881 cggaggatgt gcgtgcgctg ggaggcgttc gcttcccggt ggacgcacca gctggtgtgc
    20941 gtgagcgacg atgagctcgc gaccggccgc gcggccggcg tgacggcacc ggccgaggtc
    21001 gtgtgcaacg gcatcgacac cacgcggctg cggccggcag accggagcgc ggcacgacgg
    21061 cggctcgggt tgcctgagcg cccgaccgcg gtgtgcgtcg gccggctggc gccgcagaag
    21121 ggccaggacc tcctgctcgc cgcctggcct gacgtgctcg ccgacgtccc gcacgcccaa
    21181 ctcgtgctgg tcggcgacgg tccgatgagg actgcctggc agaacggcca ggagtccgtc
    21241 ctgtggtggg gtcacagcga caacgtcgag gacttctacg cggctgcgga tgtcgtcgtg
    21301 ctgccgtcac gcgccgaggg catggcgctg gtgccgctgg aagcgatggc ctgcgggcgg
    21361 tccgtcgtcg cgttcgacgt ggacggggtg cggcagagcc tcggatcggc cggggcggtc
    21421 gtgccaggag aagacaccgc cgcactcggg caggcgctcg ccacgcggct cgctgacccg
    21481 tcactcgcac accgggaagg ccacgccgga cgacgacgcg ccgagatgtt gttcgaccgc
    21541 gcccggatga ccgaccagat catcacgctc gtggaaaaac tcgaaggaga cgcccgatga
    21601 gggtcgcgta cctgctgacg caggaccggg gtggcccggt cgacgtcacc gtccgcctcg
    21661 ccgccgcact gcaggcgtcc ggcgaggccg aggtcaaggt cttcggcccg gttcccgcgc
    21721 gcgacgcgca cctggtcgag cacgaggaga tctcggtgcc gagcaaggga gatctgcgcg
    21781 ccagccgtca ggcacgcgcg gcactgcggg cgtggcggcc ggacgtcgtg cacgcgcagg
    21841 accgccgcag cgggctcgtg tgtgccgggc tcggcgacat cccggtcgtg cacacctacc
    21901 acggtgtgcc ggacgacgtg ggcgagccgt ggttccgcgg tgccgcacgg gcaccgaggc
    21961 cgtcgacgta cgcgatggcc gtgctcgccg ccgacgccct tgtcgcgcgc cgcgtggacc
    22021 gcacggtggt gccggcaccc gcg
//
