LOCUS       NZ_QLTT01000003        20402 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Lentzea atacamensis strain DSM 45479 Ga0215649_103, whole genome
            shotgun sequence.
ACCESSION   NZ_QLTT01000003
VERSION     NZ_QLTT01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea atacamensis
  ORGANISM  Lentzea atacamensis
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 966676)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 966676)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Expected Final Version            :: No
            Genome Coverage                   :: 111.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 11:04:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,181
            CDSs (total)                      :: 9,101
            Genes (coding)                    :: 8,972
            CDSs (with protein)               :: 8,972
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 6 (5S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 27 of 129
            Pseudo Genes (incomplete)         :: 107 of 129
            Pseudo Genes (internal stop)      :: 5 of 129
            Pseudo Genes (multiple problems)  :: 10 of 129
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:43:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 277013
            Orig. end                         :: 297415
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QLTT01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20402
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20402
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20402
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[<10000:10402](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <10001..10402
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(44..445)
                     /locus_tag="C8D87_RS16035"
                     /old_locus_tag="C8D87_103234"
     CDS             complement(44..445)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020495029.1"
                     /locus_tag="C8D87_RS16035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103234"
                     /product="SsgA family sporulation/cell division regulator"
                     /protein_id="WP_109638107.1"
                     /transl_table=11
                     /translation="MTNVTRVGAESVFAFIAPSGRPMPVEVELGYRADDPHAVTMTFRM
                     GRQETVWLVSRDLLADGLITTSGAGDVRLRPYNSTTAVLELRSDVSEAIFHVRSSELQE
                     FLNSTYDVVAPGHENDYVDFDAELRKLLD"
     misc_feature    complement(500..514)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.49"
                     /tool="antismash"
     misc_feature    529..538
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     misc_feature    534..549
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.04"
                     /tool="antismash"
     gene            complement(545..1486)
                     /locus_tag="C8D87_RS16040"
                     /old_locus_tag="C8D87_103235"
     CDS             complement(545..1486)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1208: pirin
                     domain-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007035418.1"
                     /locus_tag="C8D87_RS16040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103235"
                     /product="pirin family protein"
                     /protein_id="WP_112227679.1"
                     /transl_table=11
                     /translation="MSNVEAEPAEVTCSSTPGGAEILEPRDVPLGGPRAMSVRRTLPQK
                     QRSLIGAWCFCDHYGPDDVKMDVAPHPHTGLQTVSWLFTGEIEHRDSHGVHAFVRPGEL
                     NLMTGGRGIAHSEVSTPSSTVLHGVQLWVALPDAHRDAPRDFQHYAPPAVTLDGAAVRV
                     FLGELAGSTSPVTTFTPLLGAEIILPAGATIELGVAPGFEHGVLLDTGDVTVGETALTP
                     GALGYVGTGRTTLTLGTRDGARVVLLGGEPFGEEIVMWWNFVGRTHDEIVSYRDEWQAE
                     ADRFGRVDGYDGVRLPAPPLPGGRLRPRGNPA"
     gene            complement(1483..3219)
                     /locus_tag="C8D87_RS16045"
                     /old_locus_tag="C8D87_103236"
     CDS             complement(1483..3219)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803641.1"
                     /locus_tag="C8D87_RS16045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103236"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_233442122.1"
                     /transl_table=11
                     /translation="MRGLAGRVVAGAALLATVAMLPWLSGTDPAQTVLRARSGDQDPTP
                     EQLAAVRDELGLDNGPFTHLARWLSGDAGTSWVSGEPVLPAVSNAFAVSLTLMAGALVV
                     TIAVAALLCARTTYLGSRQLLRDSRAGTGAAFLAALPKFLLASLLATVFAVWLGWFPSG
                     GWQGPASMVLPAFALGVPSGAVIGALLEQSLPATFDEPWVRTWHACGFTSGRIAWHALR
                     GALAGVLPQFLPSVVGLVGGAVAVEKIFNIPGLGRLALDAALAQDLPPLQTATLGLILL
                     GFAAGLLVQLLRRALLGPALRDGGLMATRPPVLPPRRSARWVAAFCAVTLITLVVAGLL
                     RDPLQVDTASRLLSPSLAHPLGTDALGRDVLARLGHGAVRTTGVAVAVTAVCVVLGLLL
                     ALTGKISSGLTEMMSTLPAVLAGLLTTAVTGPSVWGAAAAVCLVGWTPYAAQAAAQFEQ
                     ERATDHITASVALGASPAHLLRHHLLPAVLPPLLRNALLRLPTTVLVLASLGFLGLGEQ
                     PPTPEWGRLLSENQQYLELAPWTTLGPACALVLLSVLAVTGTATRRPARRSAAASGLRS
                     AT"
     gene            complement(3219..4727)
                     /locus_tag="C8D87_RS16050"
                     /old_locus_tag="C8D87_103237"
     CDS             complement(3219..4727)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020639232.1"
                     /locus_tag="C8D87_RS16050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103237"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_112227681.1"
                     /transl_table=11
                     /translation="MRSPLHRLFAALALTPLLAGCFAAGGDANTATSGRLKVALAVPPV
                     QALSPYSNDATVLGKLSVAEGLTALGKDGAAAPALAKSWTRKDDTTWVFELRQAKFQDG
                     TEFTAESVVNALDHAGAAKSKPRVLSDVTLTVKADDADTVTITTKTADPVLPLRLASPA
                     LGILAAKAYAADGTVTPIGTGTGPFKITKLTGKTGATLDRFDDYWGGQAKAAGIDVSWI
                     ADGAARTNALRSGEVDIAEWIPTAQAKLLDVNTRHDVPSVRTDSLILNTAAGIFTDESL
                     RASARAAVDGSALVNSVFGGYADAAQGLFGPAVGWASGQRVPVTGRATAATTDEIKAKT
                     QGRTLRLAAYTNRAELPEAASVLQQQLEKAGFTVQQDVREYTQMEADLLAGKYDALLLS
                     RVTLLDTGDAVAYLTSDFMSTGVYNIADLKDPTVDQAIAAAAAEAGTAERQQKIMRAEA
                     EILRTGAVIPLVNEKVVQGVSTRVEGVLLDPRERSLITVDTRLK"
     misc_feature    complement(4797..4815)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 26.69"
                     /tool="antismash"
     misc_feature    complement(4809..4822)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.67"
                     /tool="antismash"
     gene            4902..5855
                     /gene="zapE"
                     /locus_tag="C8D87_RS16055"
                     /old_locus_tag="C8D87_103238"
     CDS             4902..5855
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /gene="zapE"
                     /inference="COORDINATES: protein motif:HMM:NF040713.1"
                     /locus_tag="C8D87_RS16055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103238"
                     /product="cell division protein ZapE"
                     /protein_id="WP_215732326.1"
                     /transl_table=11
                     /translation="MNLRDALLAHVSGSGYELDAAQLVAVDRLAELGERRRGVYLHGPV
                     GRGKSFLADAFFDVLPVRRKRRVHFHSFFQELHARISARLHSPGAVKKAVDELIGRCDV
                     LAFDEFHLHDVGDAMLMTRLLEVLKARGVMVVATSNYPPDGLLPNPLYHDHFLPGIALV
                     KELMDAVELNGATDYRHLHGRPRSRFETGSIVTDAEPPAAPVVLEINGRDVTALGIGGG
                     RIWFDFGDLCEKPTSTQDYLVLADRYDDWVITAVPRLETCDREAQQRFSNVVDVLVDRD
                     VRLTLVSDHPLSEIVGGDSLDLVRTASRLELINTTG"
     gene            5920..6693
                     /locus_tag="C8D87_RS16060"
                     /old_locus_tag="C8D87_103239"
     CDS             5920..6693
                     /GO_function="GO:0005216 - monoatomic ion channel activity
                     [Evidence IEA]"
                     /GO_process="GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020669907.1"
                     /locus_tag="C8D87_RS16060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103239"
                     /product="ion transporter"
                     /protein_id="WP_112227683.1"
                     /transl_table=11
                     /translation="MLRARVGSVVESNRFQLFIIGVIVVNAITLGAETSTLLHAEFGPV
                     LTTIDHLALVIFTFELAARLYASGWKFFKDPWNVFDFVIVAIALIPTAGPLSVLRSLRI
                     LRALRLVAMVPSMRRVVTALVRSIPGLVSLSGLLVLLVYVGGVIASNLFGDTGDPRFSG
                     LGPTLLTLFQITTGDGWSDVMRDLMGQKPFAWVFFLVYLLVGTFTMLNLFIAVVCSAMQ
                     EEITLPAPRTASHDDLLLQEVRALRDEVRALRSAA"
     misc_feature    complement(5969..5984)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     gene            complement(6755..9421)
                     /locus_tag="C8D87_RS47655"
                     /old_locus_tag="C8D87_103240"
     CDS             complement(6755..9421)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024627.4"
                     /locus_tag="C8D87_RS47655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103240"
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_233442123.1"
                     /transl_table=11
                     /translation="MNPSASCQITEAELATQFNVRPNDSADDSAGLQAAIDSIRTQCSP
                     TASYSKLSLITLPPGELRVSKELHVDADYLIIRGAGATTTKVVYTPDANTRYDALTPDG
                     SDWDEDGMTFGQGKGGWLWPGRGLFRVQSRGVHTAYASDYAAAPENRKDIFEGTINVHW
                     KAGTKVRAAAKAGDRSIQVQSVTNIKPGTLVNVRAANSVKFYEQQFATGTPYPMLNMHM
                     RQQIFTVVSVSSNTVTLDKPLEFDVPVNSTSDGSPAIDGTTYDSKVSPLVDPVVGVGFE
                     NFGFTQTMPSLNPAEAVNNYGNMAPADAMHGIVFKWAANSWVKGIRAEMTGSHPIVTEE
                     AKNLQIVDNHLDGSWNKGKGGNGYFRGSRVWDSLYAGNTSRNLRHFTFQWSASGNVVVG
                     NDFDSDLNLHGGWERNNLFELNTVRVSYAHRSGNCRANCGEEGGGGPDDSNWFPIWWGA
                     GKKAVKWSGATGPRNVFFNNEMSKQLAADGAYQPYYPDRQRIHQFGWNGNAYKHLDIGG
                     TPIADWAKNEQRDYTGGHGVDNSRTDSAKSLFLRNVPGSTEPPPGEETPGTVTTAEQLK
                     AALANAKPGETITLAPGTYRGSFVTTKAGTASAPITLTGPPTAVLVNDGPSGTAPTPCP
                     VPTAGWDSGYGLWLYNAPYWNIKGITVAESKKGIILDNSHHVTIDGVTVRRTDEEGVHF
                     RRSSADGVIKNSTITDAGVVTKDYGEGVYIGSANSNWKCHGNSGGVDRSDRVQVLNNKI
                     GPNVSAEHIDVKEGTQGGVIRGNTFNGTGISGANSADSWVDVKGTGYLIEGNTGTFASP
                     GTFKNGYETHNPSTTPPFLNGCGNVWRDNRSDLGNVGEYGIYVVSTSKCKEKPNVVHAS
                     NTVTRAKKGLTNVPVTP"
     misc_feature    9618..9633
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.35"
                     /tool="antismash"
     misc_feature    9712..9723
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.85"
                     /tool="antismash"
     gene            <10001..10402
                     /locus_tag="C8D87_RS16070"
                     /old_locus_tag="C8D87_103241"
                     /pseudo=""
     CDS             <10001..10402
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225102.1"
                     /locus_tag="C8D87_RS16070"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103241"
                     /product="terpene synthase"
                     /pseudo=""
                     /sec_met_domain="T1TS (E-value: 7.8e-28, bitscore: 93.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="QHDTFYTSMTLIDAVGGYELPVPLYYDPRVRQLLTAAGTASVLVN
                     DLVSVEKGAADEKPVCNTVLQIAADRECSIAEATARTVELHNQLVRDFEAGHRALLAVP
                     SVELHRFLKGTKAWMGGGFEWHTTHPRYK"
     gene            complement(10393..10896)
                     /locus_tag="C8D87_RS16075"
                     /old_locus_tag="C8D87_103242"
     CDS             complement(10393..10896)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672427.1"
                     /locus_tag="C8D87_RS16075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103242"
                     /product="DUF488 domain-containing protein"
                     /protein_id="WP_112227684.1"
                     /transl_table=11
                     /translation="MRRIATIGVYGFTAETFAEKLTSAGVGLLLDVRQRRGVRGSEYAW
                     ANSAQLQRLLAAADIGYRHVKELAPTTEMRQLQYREDDRQGVGKRDRVALAPEYTEHYT
                     REILDPFDLGALVAELPSSTTTALLCVERDPEACHRSLVAARLHTDHRLPVTDLRPDQG
                     LNYL"
     gene            complement(10958..11296)
                     /locus_tag="C8D87_RS16080"
                     /old_locus_tag="C8D87_103243"
     CDS             complement(10958..11296)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629321.1"
                     /locus_tag="C8D87_RS16080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103243"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_109638113.1"
                     /transl_table=11
                     /translation="MATEPNDLGRFFIERGNAGDVDGLVALYEPDAVLAFPPGNIATGH
                     AEIRKVYEQFVAAAPELLPGRQHPALVSGDLALTASTLTTGEMTVEVARRQPDGSWLWV
                     LDQPVLVP"
     gene            11373..12344
                     /locus_tag="C8D87_RS16085"
                     /old_locus_tag="C8D87_103244"
     CDS             11373..12344
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032105.1"
                     /locus_tag="C8D87_RS16085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103244"
                     /product="WYL domain-containing protein"
                     /protein_id="WP_112227257.1"
                     /transl_table=11
                     /translation="MRADRLVSLVLLLRRHGRMSATALARELEVSTRTVLRDIDALSAA
                     GVPVYAERGRHGGFALLPGFQTELTGLNHDEALALLVAGSRRGAQAFGLGTALASAMRK
                     VVDALPESYRATAADAAQRLLIDPETDLLARRQITDEVPDAVVAEVRRAVFAGHKLRIH
                     YAAAGQQPKWRTVDPIGLVTVREQGYLLATRSGEDRTYRLSRIVAAEELPEPAERPDRV
                     DLDRAWQERSARFRAGDDQVTVLLRLNPARRGDLMAVAVLTEETGADGWLRLEVTFQDA
                     RHAEWAVWQLSTNAEVLTPQWLRASLRDRAAALAALLTVSGG"
     gene            12415..12816
                     /locus_tag="C8D87_RS16090"
                     /old_locus_tag="C8D87_103245"
     CDS             12415..12816
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015928.4"
                     /locus_tag="C8D87_RS16090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103245"
                     /product="peptidase inhibitor family I36 protein"
                     /protein_id="WP_146231615.1"
                     /transl_table=11
                     /translation="MIRKTMMVLAGAAFAASLVSLPASAAPSPSLIEANDVSAAAWSDC
                     PAARMCIWTGLDGNGGIGYFANGDANLGAAPGPSGLNNTAESAWNRSGSRFCFYDGANY
                     SGFLGDVLPGEQGNIKPEYRNRISSLKTC"
     gene            12831..13187
                     /locus_tag="C8D87_RS16095"
                     /old_locus_tag="C8D87_103246"
     CDS             12831..13187
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015928.4"
                     /locus_tag="C8D87_RS16095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103246"
                     /product="peptidase inhibitor family I36 protein"
                     /protein_id="WP_146771723.1"
                     /transl_table=11
                     /translation="MVTGRAAALVAGAVMAGSLFAAAPAFASTAAAAQCPANRFCAWTG
                     PGHTGTSATFATGAFELGGQADNNIESVRNRTSSRWCLYDLRGFRGLLDVVEPGEEGDL
                     PAPAWNKVSSLRVC"
     gene            complement(13195..14922)
                     /locus_tag="C8D87_RS16100"
                     /old_locus_tag="C8D87_103247"
     CDS             complement(13195..14922)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.4"
                     /locus_tag="C8D87_RS16100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103247"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_170166443.1"
                     /transl_table=11
                     /translation="MGTPQTRTVLALLVWHANEVVPLSRMIDELWGARPPSSAKVQLQG
                     IISRLRRLLGRERITTTPTGYVLHATTAELDVELVRADLARARSLIADGEVALGASTLR
                     AALGRWDGPVDPPLVESVACRLDELRMTVLEERIDAELLLGGDADLIGELTAVVAEHPL
                     RERFRAQLMTALARRGRVSEALDVFHSFRRTMVAELGVEPSARLCSLHTRILRGEQDTR
                     PAFPMPRKAHRPRQLPPALPDFVSRADLLTELSDVLTGAGTRPPLVVVSGTAGLGKTSF
                     VVQLAHHVRERFPDGQLFASLRGDDTMAALRQFVRALGVPADLVPSAEDECSALLRDLL
                     AGREVLLVVDNAGDAGQVRPFVPAEPGCAVLVTSRRSLTELEGARLVRLCLFDAAESAE
                     LLTRITGAPPGEALVARCGGLPLALRIAGALLLDRPHWTSDDLAARLSDERTRLDWLEA
                     GDLDVRASFNASYRQLPAPHQTLFRRMGLLPAAPVPGWLAAALLDTGQDHAERVLEDLV
                     SWHLVSAVDRGPTIRYGMHDLVRCFSVEQAETEQERDAVITRARAAIARVAAFSTAAR"
     gene            15403..18525
                     /locus_tag="C8D87_RS16105"
                     /old_locus_tag="C8D87_103248"
     CDS             15403..18525
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801746.1"
                     /locus_tag="C8D87_RS16105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103248"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_233442124.1"
                     /transl_table=11
                     /translation="MATRSVRIQVLGSMRAWKDGAELELGPPARRAVLGLLVLAEGEPV
                     AAGSLIDALWGERPPRSAVNVLQTHVKHLRRLLEPGRSSRSSSEVLPYVNGGYAVNQAV
                     VTVDLTTFRSLVAEANEAYRNDRWDHVAAGLGEALVLWRGRPAADIPLLATHPKVVSLI
                     AKHREVVARHGDAMIAIGAAAEVLPEMAEAAAEQPLDESAQARLIRAYHAAGHRAKAFQ
                     TYHEVRDRLVEELGIDPGPELRAAHATLLHDDGRTAAAQSRPVPRVPRQLPARPAGFTG
                     RTAQLSTLDDLVPASSGGALAIAAVSGTAGVGKTALAVHWGHRVSDRFPDGQLYANLRG
                     HTRGGAARPIEVLAQFLSALDVPAERVPVDVEAASAMFRTLTTDRKMLVLLDNAAGPDQ
                     VRPLLPAGPGCLVVVTGRDRMTGLVAMHGARQLTLDVLNPDDALELLASVLGPGRVRAE
                     PAAAADFAKLCAYLPLALRIAAANLSDRPGYGIDDYVLELREGNVLTALAVPGDEQAAV
                     RAAFDLSYAALPAAAQRLFRLLSLIPGLDASTEAIAALNGTDPGPLLDRLAGAHLVEPS
                     APGRYSFHDLLRRYAAEQASSQETPADRESALRRLYDWYLHAVDTAARHLYPHMLRLPV
                     PELDARTPAGVTGPAEATSWLDAERGNLVAAVRSGPRPTAWLLADALRGYFWLSTRRVE
                     WLATAEAGLAAAEEAGDPRARAAGRLSLADLYFRQGRYREAVRHYTHAQLLARQAGWVE
                     AQAAVLGNLGCVYWQSGRLEAAAARFGRCLEVSRSIGQSAGEAVALGNLGLVHWEMGRL
                     AQAAEHYTLALNRHRQIRSRYGEAINLGNLGHVQRLRGLPGEAAQLLIRALALHREGGN
                     RSSEAQTRSRLAATYLDLGRGREALEFARTGLVQAQETGDPRIEVEALAVLATADHRLG
                     HRADAIRHYRQALDLVRNTGDRYPEIEILIGLATVTSDVEHARHALDLAERGGYRALQG
                     QAMAALAGILLASGKPRDSASHASRALEIHRETGHRQAEAFTLAVLERAGG"
     gene            complement(18526..18960)
                     /locus_tag="C8D87_RS16110"
                     /old_locus_tag="C8D87_103249"
     CDS             complement(18526..18960)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D87_RS16110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D87_103249"
                     /product="hypothetical protein"
                     /protein_id="WP_112227261.1"
                     /transl_table=11
                     /translation="MKATIIGCAVVLFAGLPITTAQAAEEKCETPLLTSETVRLAEPGK
                     WSYTYQVSWCVDEGRITFITPHVTHEADGTTCVWVTNAEEYEKPVPNGDGAWETFNMSE
                     FSCKDSAGRPASVTPWAKIIIQPNGASHIPEKGIGDRIVE"
     misc_feature    18945..18959
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            19102..19968
                     /locus_tag="C8D87_RS16115"
                     /old_locus_tag="C8D87_103250"
     CDS             19102..19968
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801744.1"
                     /locus_tag="C8D87_RS16115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D87_103250"
                     /product="DUF4394 domain-containing protein"
                     /protein_id="WP_112227262.1"
                     /transl_table=11
                     /translation="MKARTKRGVAAAAVVASVAAAVIGGGGSSAAQPSGLRAFGISADG
                     TLMVTFTTNLPQELNWVRQIQGFSGDTAAIGLDQRVQDGLLYLVGNKGGIYTVKLPNPP
                     SQPNPIITKVSQLTVALHGTNFGVDFNPAADRLRVTSDTGQNLRHDLNAHSTVADTMLS
                     TPPTPGATKGVTAAAYTNNDLDPGTATTLFDIGTMTDQVLIQSPANNGTLAPTGSLTVD
                     AGSNAGFDIFSTLSGGKAVSVAGFATLVAPNGTSSLYSINLLNGTATSLGQFPLPITDL
                     AISLTGS"
     misc_feature    20246..20260
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.14"
                     /tool="antismash"
ORIGIN
        1 gtctgaccgc gaattcgccc ggcaacgttc cgggccacgc cacctagtcg agcagcttgc
       61 gcagttcggc gtcgaagtcg acgtagtcgt tctcgtgacc gggggcgact acgtcgtacg
      121 tggagttgag gaactcctgc agctcggagg accgcacgtg gaagatggcc tccgacacgt
      181 cggaccgcag ctccagcacg gcggtcgtcg agttgtacgg ccgcagccgc acgtcacccg
      241 caccgctggt ggtgatcagt ccgtcggcga gcaggtcgcg gctgaccagc cacaccgttt
      301 cctggcgtcc catgcggaac gtcatggtca cggcgtgcgg gtcgtcggcg cggtagccga
      361 gctcgacctc gacgggcatg gggcgcccgg acggggcgat gaaggcgaag acggactcgg
      421 cgcccactcg tgtcacgttc gtcatgcccc cttagacgcg cggcaacctt cgtggatgcc
      481 tcgctcagga aaagcgatcg gaacgtgatt ttcaacggtc cgggagtatg acttttgaca
      541 accgtcacgc ggggttgccg cgcggacgca gacggccacc gggaagtggt ggagctggca
      601 aacggacgcc gtcgtaaccg tccacccggc cgaacctgtc ggcctccgcc tgccattcgt
      661 cccggtagga gacgatctcg tcgtgggtgc ggcccacgaa gttccaccac atgacgatct
      721 cctcgccgaa cggctcgccg ccgagcagca caacccttgc gccgtcccga gttcccaagg
      781 tcagcgtggt gcggccggtg ccgacgtagc cgagcgcgcc gggggtgaga gcggtttcgc
      841 cgacggtgac gtcaccggtg tcgagcagga cgccgtgctc gaacccggga gccacgccga
      901 gctcgatcgt tgcccctgcg ggcaggatga tctccgcgcc gagcagcggt gtgaacgtgg
      961 tcacaggaga cgtcgaaccc gccagttcgc cgaggaacac ccgcaccgcg gcgccgtcca
     1021 gcgtcaccgc cggcggcgcg tagtgctgga agtcgcgcgg ggcgtcccgg tgggcgtccg
     1081 gcagcgcgac ccacagctgc acgccgtgca ggacggtgga cgacggggtc gacacctcgg
     1141 agtgcgcgat gccgcgtccg ccggtcatca ggttcagctc tcccggccgc acgaacgcgt
     1201 gcacgccgtg gctgtcgcgg tgttcgatct cgccggtgaa gagccagctg acggtctgca
     1261 gcccggtgtg ggggtgcggg gcgacgtcca tcttcacgtc gtcgggcccg tagtggtcgc
     1321 agaagcacca cgcgccgatg agcgatcgct gcttctgcgg caacgtccgg cgcaccgaca
     1381 tcgcgcgcgg accgcccagc ggtacgtccc tcggctccag gatctccgcc ccaccggggg
     1441 tggagctgca cgtcacttcc gcgggctcgg cctcgacatt gctcacgtgg ccgatcgtag
     1501 gccggacgct gccgctgatc ggcgtgccgg gcgtcgcgtc gcggtgccgg tcacggcgag
     1561 caccgaaagc aggacgagcg cgcaggccgg tccgagcgtc gtccacggcg cgagctcgag
     1621 gtactgctgg ttctccgaca gcagccggcc ccactcaggg gtgggcggtt gctcgcccag
     1681 accgaggaaa ccgagtgagg cgagcacgag gacggtggtg ggcaggcgca gcagcgcgtt
     1741 gcgcagcaag ggaggcagca cggccgggag caggtggtgg cgcagcaggt gcgccggtga
     1801 ggcgcccagc gcgaccgacg cggtgatgtg atcggtcgcc cgctcctgct cgaactgcgc
     1861 agcggcctgt gcggcgtacg gggtccagcc caccaggcag accgccgcgg cggcgcccca
     1921 cacggacggg ccggtgaccg cggtcgtgag cagcccggcc aggacggcag gcaaagtcga
     1981 catcatctcg gtcagccccg agctgatctt tccggtcagc gcgagcagca gcccgaggac
     2041 cacgcagacc gccgtcaccg cgacggcgac ccccgtcgtg cgcaccgcgc cgtgtccgag
     2101 ccgggcgagt acgtcgcggc cgagcgcgtc cgtgcccagc ggatgggcga gcgacgggga
     2161 cagcaggcgg gaggccgtgt cgacctgcaa cgggtcgcgg agcagcccgg ccacgaccag
     2221 cgtgatcagg gtgaccgcgc agaacgccgc cacccagcgg gccgaacgac ggggcggcag
     2281 gaccggggga cgcgtggcca tgagcccgcc gtcgcgcagt gctgggccga gcagagcgcg
     2341 gcgcaggagc tggaccagca ggcccgcggc gaagccgagc aggatgagac ccagcgtcgc
     2401 ggtctgcagc ggtggcaggt cctgggccag tgcggcgtcc agcgcgagcc tgccgaggcc
     2461 ggggatgttg aagatcttct ccaccgccac cgcgccgccg accagcccga cgacgctggg
     2521 caggaactgc gggagcactc ccgccagggc gccgcgcagc gcgtgccagg cgatgcggcc
     2581 ggaggtgaac ccgcaggcgt gccaggtccg cacccacggc tcgtcgaacg tggcgggcag
     2641 cgactgctcg agcagggcgc cgatcaccgc cccggacggc acgccgagcg cgaacgcggg
     2701 cagcaccatc gacgcgggcc cctgccagcc gccggaggga aaccacccca gccacaccgc
     2761 gaacaccgtc gcgagcagtg aggcgagcag gaacttgggc agtgcggcga ggaacgccgc
     2821 ccccgtgccc gcccggctgt cgcgcagcag ctgccgcgat ccgaggtacg tggtgcgggc
     2881 gcagagcagg gcggcgacgg cgatggtcac cacgagggcg ccggccatca gcgtgagcga
     2941 gacggcgaag gcgttcgaca ccgcgggcag gacgggttcg cccgagaccc aggaggtgcc
     3001 ggcgtcgccg ctcagccatc gcgcgaggtg cgtgaacggc ccgttgtcca gaccgagctc
     3061 gtcccggacg gctgccagtt gctccggggt ggggtcctgg tcaccggaac gggcccgcag
     3121 caccgtctgc gcgggatccg tcccggacaa ccagggcagc atcgcgacgg tcgccagcag
     3181 agccgctccg gcgacgacgc ggccggccag accgcgcact acttcagccg ggtgtcgacg
     3241 gtgatcagcg agcgctcacg cgggtcgagc agcactccct cgacgcgcgt gctgacgccc
     3301 tgcacgacct tctcgttgac cagcgggatg acggcgccgg tgcgcaggat ctccgcctcc
     3361 gcccgcatga tcttctgctg ccgctccgcg gtgcctgctt ccgcggcagc ggcggcgatc
     3421 gcctggtcga cggtggggtc cttcaggtcg gcgatgttgt agacgccggt gctcatgaag
     3481 tcgctcgtga ggtacgcgac cgcgtcaccg gtgtcgagca gcgtcacccg tgacagcagg
     3541 agcgcgtcgt acttgccggc gaggaggtcg gcctccatct gcgtgtactc gcgcacgtcc
     3601 tgctggacgg tgaacccggc cttctccagc tgctgctgca gaacggacgc ggcctcgggc
     3661 agttcggcgc ggttggtgta ggcggccagg cgcagcgtcc tgccctgcgt cttcgccttg
     3721 atctcgtcgg tggtcgcggc ggtcgccctg ccggtcaccg ggacccgctg gccggacgcc
     3781 cacccgacag cgggtccgaa gagaccctgc gcggcgtcgg cgtagccgcc gaagaccgag
     3841 ttgacgagtg cggaaccgtc cacggccgcg cgggccgagg cccgcagcga ctcgtcggtg
     3901 aagattccgg cggcggtgtt gaggatcagg ctgtcggtcc gcacggacgg cacgtcgtgg
     3961 cgggtgttca cgtcgagcag cttcgcctgg gcggtgggga tccactcggc gatgtccacc
     4021 tcgcccgagc gcagtgcgtt ggtgcgagcg gcaccgtcgg cgatccagga cacgtcgatg
     4081 ccggccgcct tggcctgccc gccccagtag tcgtcgaagc ggtcgagcgt cgcgcccgtc
     4141 ttcccggtca gcttggtgat cttgaacgga ccggtgccgg tgccgatcgg ggtgacggtg
     4201 ccgtccgccg cgtacgcctt cgcggcgagg atgccgagcg cggggctggc gagccgcagg
     4261 gggagcaccg ggtcggcggt cttggtggtg atcgtgacgg tgtcggcgtc gtctgccttc
     4321 acggtcagcg tcacgtcgct gaggacgcgg ggcttggact tggccgcgcc ggcgtggtcg
     4381 agcgcgttga cgaccgactc ggcggtgaac tccgtgccgt cctggaactt cgcctggcgc
     4441 agctcgaaga cccaggtggt gtcgtccttg cgggtccacg acttcgccag tgccggcgcg
     4501 gcggcgccgt ccttgcccag cgcggtgagc ccttcggcca cggacagctt gcccagcacg
     4561 gtggcgtcgt tgctgtacgg cgacagcgcc tgcaccggcg gcacggcgag cgcgaccttc
     4621 aaccggccgc tcgtcgcggt gttcgcgtca ccgcccgcgg cgaaacaacc ggccagcagc
     4681 ggggtgaggg cgagcgcggc gaagaggcgg tggagcggtg agcgcacggt gggtcctgtc
     4741 ggggcggaga agtcggtcac gcctctgatc ggtggaatcg aggccgggtc agcttataag
     4801 gcaagcctta ccaatgattc taaggtgatt gaaatctcaa cgatgaggtg ggtcgcaggt
     4861 ggcgccgggg cgcgtgatcg tagggtggcg cgggggtact tgtgaatctt cgcgacgcgc
     4921 tgctcgcaca cgtgtcgggc agcggctacg aactggacgc cgctcagctg gtcgccgtcg
     4981 accggctggc ggagctgggg gagcgccgcc ggggcgtcta cctgcacggg ccggtcggcc
     5041 ggggcaagag cttcctcgcg gacgccttct tcgacgtgct gcccgtgaga cgcaaacgcc
     5101 gcgtgcactt ccactccttc ttccaggagc tgcacgcacg catctcagcc cgtctgcatt
     5161 caccgggcgc ggtgaagaag gccgtcgacg agctgatcgg ccgttgcgac gtgctggcgt
     5221 tcgacgagtt ccacctgcac gacgtcggcg acgcgatgct gatgacccgc ctgctggaag
     5281 tcctgaaggc gcgcggtgtc atggtcgtcg ccacgtccaa ctacccgccg gacggcctgc
     5341 tgcccaaccc gctgtaccac gaccacttcc tgccaggcat cgcgctggtg aaggaactga
     5401 tggacgcggt cgagctcaac ggcgccaccg actaccggca cctgcacggc cgcccgcgct
     5461 cccggttcga gaccggctcg atcgtcaccg acgccgaacc accggccgcg ccggtcgttc
     5521 tggagatcaa cggccgggac gtcaccgcac tcgggatcgg cggcggccgc atctggttcg
     5581 acttcggtga tctgtgcgag aaaccgacgt ccacgcagga ctacctcgtg ctcgcggatc
     5641 gttacgacga ctgggtgatc accgccgtgc cgcggctgga gacctgcgat cgtgaggcgc
     5701 agcaacggtt ctcgaacgtc gtggacgttc tggtcgaccg cgacgtccgg ctgacgctgg
     5761 tgagcgatca cccgctgagc gagatcgtcg gcggcgactc cctcgacctc gtgcgcaccg
     5821 ccagccgtct ggagctgatc aacacgaccg ggtgaacagt cggaccgctt ccaccgccga
     5881 tagcttccaa aacccctgtg ctaggagcgg tgagtgaaga tgctgcgcgc ccgcgtcggc
     5941 tcggttgtgg agagcaaccg gttccagctg ttcatcatcg gcgtgatcgt ggtcaacgcg
     6001 atcacgctgg gcgcggagac gtcgacgctc ctgcacgcgg agttcggtcc cgtgctgacg
     6061 acgatcgacc atctcgcact cgtgatcttc acgttcgaac tggccgcgcg gctctacgcg
     6121 tccggctgga agttcttcaa ggacccgtgg aacgtcttcg acttcgtgat cgtggccatc
     6181 gcgctgatcc ccaccgcggg gccgctgtcg gtgctgcgct cgctgcgcat cctgcgggct
     6241 ctgcggctcg tcgcgatggt gccgagcatg cggcgcgtgg tgacggcgct ggtgaggtcg
     6301 attcccggcc tggtgtcgtt gtccggactg ctggtgctgc tcgtctacgt cggcggcgtg
     6361 atcgcgagca acctgttcgg cgacaccggc gacccgcggt tctccggcct gggcccgacg
     6421 ttgctgacgc tgttccagat caccaccggc gacggctggt cggacgtgat gcgcgacctg
     6481 atggggcaga agccgttcgc gtgggtcttc ttcctggtct acctgctggt cgggacgttc
     6541 acgatgctca acctgttcat cgcggtggtg tgcagcgcga tgcaggagga gatcaccctg
     6601 cccgcaccca ggaccgcgtc gcacgacgat ctgctgctgc aggaggtccg ggcgttgcgc
     6661 gacgaggtgc gggcactgcg atcggctgcc tagcaggaga tcccgatcgg cgacgccgcc
     6721 gtacaccgat cgggacctct gcaacccccg actgttacgg ggtgaccggg acgttcgtaa
     6781 ggcccttctt cgcacgggtg accgtgttcg aggcgtggac gacgttcggc ttctccttgc
     6841 acttggacgt ggacacgacg tagatgccgt actcaccgac gttgccgagg tcggacctgt
     6901 tgtcgcgcca gacgttgccg cagccgttca ggaacggcgg cgtggtgctc gggttgtgcg
     6961 tctcgtagcc gttcttgaac gtgccgggcg aggcgaaggt gccggtgttg ccctcgatga
     7021 ggtagccggt gcctttcacg tccacccacg agtcggcgga gttcgcgccg ctgatcccgg
     7081 tgccgttgaa cgtgttgccg cggatgacgc cgccctgcgt gccttccttg acgtcgatgt
     7141 gctcggcgga gacgttcggg ccgatcttgt tgttgagcac ctggacgcgg tcggacctgt
     7201 cgacgccgcc ggagttgccg tggcacttcc agttggagtt cgccgatccg atgtagacgc
     7261 cctctccgta gtccttcgtc acgacgccag cgtcggtgat cgtcgagttc ttgatgacac
     7321 cgtccgcgga ggagcgccgg aagtgcacgc cttcctcgtc ggtcctgcgg acggtgacgc
     7381 cgtcgatcgt gacgtggtgg gagttgtcga ggatgatgcc cttcttggac tccgcgacgg
     7441 tgattccctt gatgttccag tacggcgcgt tgtacagcca caggccgtag cccgagtccc
     7501 agcccgcggt cggcaccggg cagggggtcg gtgcggtgcc ggacgggccg tcgttgacca
     7561 gcacggcggt cggcgggccg gtgagcgtga tcggcgcgct cgccgtgccg gccttcgtcg
     7621 tcacgaacga gcctcggtag gtgccgggtg cgagcgtgat ggtctcgccg ggtttcgcgt
     7681 tggccagcgc ggccttcagc tgctcggcgg tggtcaccgt gccgggcgtc tcctcaccgg
     7741 gtggtggctc ggtggaaccc ggaacgttcc tgaggaacaa cgacttcgcc gagtcggtcc
     7801 tggagttgtc cacgccgtga ccgccggtgt agtcgcgctg ctcgttcttc gcccagtccg
     7861 cgatcggagt gccaccgatg tcgaggtgct tgtaggcgtt gccgttccag ccgaactggt
     7921 ggatccgctg ccggtcgggg tagtacggct ggtaggcgcc atccgcggcc agctgcttgg
     7981 acatctcgtt gttgaagaac acgttgcgcg gcccggtggc acccgaccac ttcaccgcct
     8041 tcttgccggc gccccaccag atcgggaacc agttcgagtc gtcgggaccg ccgccgcctt
     8101 cctcaccgca gttcgcgcgg cagttgccgg agcggtgggc gtaggagacg cggaccgtgt
     8161 tgagctcgaa caggttgttg cgctcccagc cgccgtgcag gttcaggtcg gagtcgaagt
     8221 cgttgcccac cacgacgttg cccgacgcgg accactggaa cgtgaagtgc cgcaggttgc
     8281 gcgaggtgtt gccggcgtag agcgagtccc acacccgcga gccgcggaag tagccgttgc
     8341 cgcccttgcc cttgttccac gagccgtcga ggtggttgtc gacgatctgc aggttcttgg
     8401 cctcctcggt gacgatcggg tgcgacccgg tcatctccgc gcggatgccc ttcacccacg
     8461 agttcgccgc ccatttgaag acgatgccgt gcatcgcgtc ggccggtgcc atgttgccgt
     8521 agttgttgac ggcctcggcg gggttgaggc tcggcatcgt ctgcgtgaag ccgaagttct
     8581 cgaacccgac gccgacaacc gggtccacga gcggcgacac cttggagtcg taggtcgtcc
     8641 cgtcgatcgc cggtgaaccg tccgaggtgg agttgaccgg gacgtcgaac tccagcggtt
     8701 tgtcgagcgt gacggtgttc gacgacaccg agacgacggt gaagatctgc tggcgcatgt
     8761 gcatgttcag catcgggtac ggggtcccgg tggcgaactg ctgctcgtag aacttcaccg
     8821 agttcgcggc gcggacgttg accagcgtgc ccggcttgat gttcgtgacc gactggacct
     8881 ggatggaccg gtcaccggcc ttcgcggcgg cgcgcacctt cgtgccggcc ttccagtgca
     8941 cgttgatcgt gccctcgaag atgtccttgc ggttctcggg agccgccgcg tagtcgctcg
     9001 cgtaggcggt gtgcacgccg cgcgactgga cccggaacag gccgcggccc ggccacagcc
     9061 acccgccctt gccctgcccg aacgtcatcc cgtcctcgtc ccagtccgag ccgtccgggg
     9121 tgagcgcgtc gtagcgggtg ttggcgtcgg gtgtgtagac caccttcgtg gtggtcgcgc
     9181 cggcacctct gatgatcagg tagtcggcgt cgacgtgcag ttccttcgag accctcagct
     9241 cgccgggggg cagcgtgatg aggctgagct tcgaatagct cgcggtcggc gagcactgcg
     9301 tcctgatgga gtcgatcgcg gcctgcagcc cggcactgtc gtcggcggag tcgttcgggc
     9361 ggacgttgaa ctgagtggcg agttccgcct cggtgatctg acaactcgcg ctcgggttca
     9421 cctcattgtt tccgggcagc acgccattgc cgcgataccc cgccttcgac cagtcgtaca
     9481 ggccggaaat gggggaacgt cggttggctg acgagacatc caggcccgtc agtgcaggta
     9541 cggcggtcgc cgtggttgcc ggaaccgcga gtgaaccgat taagagcagt gttaacaggg
     9601 gtatggaggt tcgcgtcatt gataaccctc ttcggcaggg cgggggctat ttctttgtag
     9661 acgatggttg catatgtgtc aaacattcac attcctgaat caggtaatcc tgaaacggtt
     9721 ttcaatgacg gttttctgcc tgttcggaga gttctcggag cagctcacgg ttctgaatcg
     9781 tgcgagccga ttgggctcat tgcgagccga gtgcgccgcg accgaccggt ggcctcgcac
     9841 caggatttct gttgtgatgg cgtggaatct tgcccttaca gtcatccgga tgggcgaaag
     9901 gagcccacga aggtgggggc actggcgggg ttgtgcgggt cgagaggccc accgcagcac
     9961 gcttttccac gcacccgttc gtgaccgaac caaccctgaa cagcacgaca cgttctacac
    10021 gtcgatgacc ctgatcgacg cggtcggcgg ctacgagctg cccgtgccgc tgtactacga
    10081 cccgcgcgtc cggcagctgc tgaccgccgc gggcacggcg tcggtgctcg tcaacgacct
    10141 ggtgtcggtg gagaagggcg ccgccgacga gaagccggtc tgcaacacgg tgctccagat
    10201 cgcggcggac cgggagtgct cgatcgccga ggccaccgca cggaccgtgg agctgcacaa
    10261 ccagctggtg cgcgacttcg aggcgggcca cagggcgctg ctcgcggtgc catcggtgga
    10321 gttgcaccgg tttctgaagg gcaccaaggc ctggatgggc ggcggcttcg aatggcacac
    10381 cacccacccg cgctacaagt agttcaggcc ctggtcggga cggaggtcgg tgaccggcag
    10441 gcggtgatcg gtgtgcaggc gtgcggccac gagtgagcgg tggcacgcct ccgggtcgcg
    10501 ctcgacgcag agcaacgcgg tcgtggtcga gctcggcagc tcggccacaa gtgcaccgag
    10561 gtcgaacggg tcgaggatct cgcgggtgta gtgctcggtg tactcgggcg ccagggcaac
    10621 ccggtcgcgc ttgcccacgc cctgccggtc gtcctcgcgg tactggagct gacgcatctc
    10681 cgtcgtcggc gcgagctcct tcacgtgccg ataaccgatg tccgccgcgg cgagcaggcg
    10741 ctggagctgc gccgagttcg cccaggcgta ctcagagccg cggacaccgc ggcgctggcg
    10801 gacgtcgagc agcaacccca cgcccgcgct ggtgagcttc tcggcgaagg tttccgccgt
    10861 gaagccgtag acaccgatcg tcgcgatgcg cctcatcgtc acaacctcca ttgtggacgg
    10921 cggtgggcct ggtcgcgccg ggcccaccgc caccctgtca cggcaccagc accggctggt
    10981 ccaggaccca caaccacgac ccgtccggct gacggcgggc gacctcgacc gtcatctcac
    11041 cggtggtcag cgtggacgcc gtgagcgcca ggtcgccgct caccagcgcc gggtgctgcc
    11101 tgcccggcag cagctccggt gcggcggcga cgaactgctc gtacaccttg cggatctccg
    11161 cgtgcccggt ggcgatgttg ccgggcggga acgccagcac ggcgtccggt tcgtacaacg
    11221 ccaccagtcc gtcgacgtcg cccgcgttgc cgcgttcgat gaagaacctg cccagatcgt
    11281 tcggctcggt ggccactgtc ctgctcgtca tgtggatcac cctgccaacg aatcacgaca
    11341 tcctgtgtcg tgtattcccg tagagttttc ccatgcgtgc cgaccggttg gtctcgctgg
    11401 ttctgctgct gcgccggcac ggccggatgt ccgcgaccgc cctcgcccgc gagctggagg
    11461 tgtccacccg caccgtgctg cgcgacatcg acgcgctgtc cgcggccggc gtccccgtct
    11521 acgccgaacg cggccggcac ggcggtttcg ccctgctgcc gggtttccag accgagctca
    11581 ccgggctgaa ccacgacgag gcactcgcac tgctggtcgc cggatcacgg cgcggcgcac
    11641 aggccttcgg cctcggcacg gcactcgcct cggcgatgcg caaggtggtg gacgcgctgc
    11701 ccgagagtta tcgggccacc gccgccgacg ccgcccagcg gctgctcatc gacccggaga
    11761 ccgacctcct cgcccgccgg cagatcaccg acgaggtgcc cgacgccgtt gtggccgagg
    11821 tccggcgcgc ggtgttcgcg ggccacaagc tccgcatcca ctacgcggcc gccggtcagc
    11881 agccgaagtg gcgcacggtg gacccgatcg gcctggtcac cgtgcgggag cagggttacc
    11941 tgctggccac gaggtcgggg gaggaccgca cctaccggct gtcccggatc gtggccgcgg
    12001 aggaacttcc cgagccggcg gagcgaccgg accgggtcga cctggaccgg gcgtggcagg
    12061 aacgcagcgc gcggttccgt gccggcgacg accaggtgac cgtgctgctc cggctgaacc
    12121 cggcgaggcg gggcgacctg atggcggtgg ccgtcctgac cgaggagacc ggcgcggacg
    12181 gctggctgcg gctggaggtg accttccagg acgcgaggca cgccgaatgg gcggtgtggc
    12241 agctgtccac gaacgcggaa gtcctgaccc cgcagtggtt gcgcgcctcc ctgcgcgacc
    12301 gtgccgccgc actcgccgcc ctgctcacgg ttagtggtgg ttagtgttcg gctagcgcgg
    12361 ttccccagtc ttggtgccga ggcgagatcg cctcgcagag aagggggaat tctcttgatc
    12421 cgcaaaacga tgatggtgct ggccggtgcg gcgttcgccg cgtcactggt gtcgctgccc
    12481 gcgagcgccg cgccctcgcc gtcgctcatc gaggccaacg acgtgtccgc cgcggcgtgg
    12541 agcgactgtc ccgccgccag gatgtgcatc tggaccggcc tcgacggcaa cggcgggatc
    12601 ggctacttcg ccaacgggga cgcgaacctc ggtgcggctc ccggcccgag cggactgaac
    12661 aacaccgccg agagcgcgtg gaaccgcagc ggttcgcggt tctgcttcta cgacggggcg
    12721 aactactcgg gcttcctcgg tgacgtgctg ccgggtgagc aggggaacat caagccggag
    12781 taccgcaacc ggatctcgtc gctgaagacc tgctgacggg agacggaacc gtggttaccg
    12841 gcagagcagc agcgctggtg gccggtgcgg tgatggcggg gtcgctgttc gcggcggccc
    12901 cggccttcgc ctccaccgct gccgcagctc agtgtcccgc aaaccggttc tgcgcgtgga
    12961 ccggtcccgg ccacaccggt acgtccgcca cgttcgcgac cggtgcgttc gaactgggcg
    13021 gccaggccga caacaacatc gagagcgtgc ggaaccgcac cagctcgcgg tggtgcctgt
    13081 acgacctgcg cggcttccgg ggcctcctgg acgtcgtgga acccggtgag gaaggagacc
    13141 tgcccgcacc cgcgtggaac aaggtctcgt ccctccgcgt ctgttagggc ctggtcatcg
    13201 ggcggctgtc gaaaaggcgg caaccctggc gatggccgcc cgtgcccggg tgatcaccgc
    13261 gtcccgttcc tgctcggttt cggcctgctc caccgaaaag caccgcacca ggtcatgcat
    13321 gccgtaacgg atcgtcgggc cgcggtcgac cgcgctcacc aggtgccagc tgacgaggtc
    13381 ctccagcacc cgttcggcgt ggtcctgccc ggtgtcgagc agggccgccg cgagccagcc
    13441 gggtaccggt gccgcgggca gcagccccat gcgccggaac aacgtctggt gcggcgcggg
    13501 cagctgccgg tagctcgcgt tgaagctggc ccgcacgtcg aggtcgcccg cctccagcca
    13561 gtcgagcctc gtgcgttcgt ccgacagccg cgcggccagg tcgtcgctgg tccagtgtgg
    13621 acggtcgagg agcagtgctc ccgctatccg cagcgcgagc ggcaggccac cgcacctggc
    13681 caccagcgct tctcccggtg gtgcgccggt gatcctggtg agcagctcgg cggactcggc
    13741 cgcgtcgaac aagcagagcc ggaccagccg ggcgccttcg agttcggtga gcgaacgcct
    13801 gctcgtcacc aggaccgcgc agccgggttc ggcgggcacg aacggccgca cctgaccggc
    13861 gtcgcccgcg ttgtcgacga cgagcagcac ctcgcgtccg gccagcaggt cccgcaacag
    13921 ggccgagcac tcgtcttcgg cggatggcac gagatccgcg ggaacgccca gcgcgcgcac
    13981 gaactgccgc aacgcggcca tcgtgtcgtc accgcgcagc gaggcgaaga gctggccgtc
    14041 cgggaagcgc tcgcgcacgt ggtgggcgag ctgcacgacg aacgacgtct tgccgagccc
    14101 tgccgtgccg gacaccacca cgagcggagg ccgggtcccg gcgccggtca gcacgtcgga
    14161 gagctcggtc agcagatcgg cacggctgac gaagtctggc agtgccggtg gtagctgccg
    14221 cggccgatgt gccttgcgcg gcatcggaaa cgcaggccgc gtgtcctgct cgccacgcag
    14281 gatccgcgtg tgcagcgagc acagtcgtgc ggacggttcg acgccgagct cggccaccat
    14341 cgtgcggcgg aacgagtgga acacgtcgag ggcctccgac accctgccgc gccgggccag
    14401 cgcggtcatc agctgggcgc gaaaccgttc ccgcagcggg tgttcggcga ccaccgccgt
    14461 cagctcgccg atcaggtcgg cgtcgccgcc cagcaggagt tcggcgtcga tgcgctcctc
    14521 cagcacggtc atccgcagtt cgtcgagccg gcaggcgacg gactcgacga gtggcgggtc
    14581 gaccggcccg tcccatcgcc cgagcgccgc acgcagcgtg ctcgcgccga gcgccacctc
    14641 accgtccgcg atgagtgagc gcgctctcgc aagatcggcg cggaccagtt cgacgtcgag
    14701 ctccgccgtg gtggcgtgca ggacgtatcc cgtcggcgtg gtcgtgatcc gctcgcggcc
    14761 gagcagtctc ctcagccgcg agatgatgcc ctgcagctgc accttcgccg acgacggcgg
    14821 cctggcaccc cacagttcgt cgatcatccg gctgagcggg acgacctcgt tggcgtgcca
    14881 cacgagcaag gccagcacgg tgcgcgtctg cggtgtgccc accgcgatct ccgtaccgtc
    14941 gctttccagc cgaaatggtc cgagcaatcg gaaaaaccac atgccccagt acctccccca
    15001 gtactgcccc ccacgacaag agtggcacag gatccggggg cggcgcgagc acttcggccg
    15061 aacccgagga ttcgtccagt caattcccgc ccaggtccgg gtgtgcgcag ccgtgacccc
    15121 attcgccgca aatatgtcgc gatcaatgat ttccgcacgc acgccccgat ttccgggaaa
    15181 cggtacgcca aatggttgtc gcggaaagct cggtgcagcg gtcgttcggc gctgacggtg
    15241 cagctaggtc ccgggtcacc caccggatcg gcggccgggg ccgggggcac caccggttgg
    15301 ctgtgcgggg aatgggctga gcggacccaa tatcgggtcc cagcggaggg cgttggactg
    15361 ttgtccttgt ggcacagctg tccgttaatt acgttcagga cagtggcaac gaggtctgtg
    15421 cgaatccagg tgctgggttc gatgcgggcg tggaaagacg gtgcggaact cgagctcggc
    15481 ccacccgccc ggcgagctgt gctgggactg ctcgtgctcg cggagggcga gccggtggcc
    15541 gccgggagcc tgatcgacgc cctgtggggt gagcgaccac cgcgcagcgc cgtgaacgtc
    15601 ctgcagaccc acgtcaaaca cctgcggcgg ttgctggagc cgggccggtc gtcccggtcg
    15661 agcagcgagg tcctgcccta cgtcaacggc ggttacgcgg tcaaccaggc cgtcgtgacc
    15721 gtcgacctga ccacgttccg cagcctggtc gccgaggcga acgaggccta tcgcaacgac
    15781 cggtgggacc acgtcgcagc agggctgggc gaggcgctcg tgttgtggcg cgggcggccg
    15841 gctgcggaca ttccgttgct cgccacgcat ccgaaggtcg tgtcgctgat cgcgaagcac
    15901 cgtgaggtgg tggcgaggca cggcgacgcg atgatcgcga tcggtgccgc ggcggaggtg
    15961 ctgcccgaga tggcggaggc cgccgccgaa cagccgctgg acgaatccgc gcaggcccgg
    16021 ctgatccgcg cgtatcacgc cgcaggacac cgggccaagg ctttccagac ctaccacgag
    16081 gtgcgggacc ggctcgtcga ggagctcggc atcgacccgg gtccggagct ccgcgccgcc
    16141 cacgcgacgc tgctgcacga cgacggcagg acggccgcgg cacagtcgcg tccggtgccg
    16201 cgggtgccgc ggcagctgcc ggcgcggccg gcgggcttca ccgggcggac ggcacagctg
    16261 tccacattgg acgatctggt gcccgcgagc tcaggcggcg cgctggcgat cgccgcggtc
    16321 tccggcaccg cgggcgtcgg caagactgcg ctcgccgtgc actggggaca ccgcgtcagc
    16381 gaccggttcc ccgacgggca gctctacgcg aacctgcgcg ggcacaccag gggcggggcg
    16441 gcgcggccga tcgaggtgct cgcccagttc ctgtccgcgc tggacgttcc cgccgagcgc
    16501 gtaccggtcg acgtggaggc ggcgtcggcg atgttccgca ccctgacgac ggaccggaag
    16561 atgctggtgc tgctggacaa cgccgcgggg ccggaccagg tccggccgct gctgcccgcc
    16621 ggtcccggct gcctcgtggt ggtgaccggc cgcgaccgga tgaccggcct ggtcgcgatg
    16681 cacggcgccc gtcagctcac gctcgacgtg ctcaaccccg atgacgcgct ggaactgctg
    16741 gcctccgtgc tggggcccgg ccgggtacgc gccgagccgg cggctgccgc ggacttcgcc
    16801 aagctgtgcg cctacctgcc gctcgcgttg cggatcgcgg ccgccaacct ctccgaccgt
    16861 cccggctacg ggatcgacga ctacgtcctg gagctgaggg agggcaacgt gctgaccgcc
    16921 ctcgcggtgc ccggcgacga gcaggccgcg gtgcgagcgg cgttcgacct ctcctacgcg
    16981 gcactgcccg cggcggcgca gcggttgttc cgcctgttga gcctcatccc cggactcgac
    17041 gccagcacgg aggcgatcgc ggcgctcaac ggcacggacc ccggaccatt gctggaccgc
    17101 ctcgccgggg cgcacctcgt cgagcccagc gcacccggtc gctacagctt ccacgacctg
    17161 ctccggcgtt acgccgccga acaggcgtcg agccaggaga caccggcgga ccgcgagtcg
    17221 gccctgcggc ggttgtacga ctggtacctg cacgccgtcg acaccgcggc ccggcacctc
    17281 tacccgcaca tgctgcgcct gccggtaccc gaactcgacg ccaggacacc cgccggcgtc
    17341 accggaccag cggaggcgac gagctggctg gacgccgaac gcggcaacct cgtcgccgcg
    17401 gtccggtcgg gaccccgtcc cacggcgtgg ttgctcgcgg acgccctgcg cggctacttc
    17461 tggttgtcca ctcgccgggt cgagtggctc gccacggcgg aagccgggct cgctgccgcc
    17521 gaggaggcgg gcgaccccag ggcacgggcc gccggccggc tcagcctcgc cgacctgtac
    17581 ttccggcagg gcaggtaccg cgaggccgtg cggcactaca cgcacgcgca actgctggcg
    17641 cggcaggcgg gctgggtcga ggcgcaggcc gcggtgctcg gcaacctcgg ctgcgtctac
    17701 tggcagtccg gccggctcga agccgccgcg gccaggttcg gccgctgcct ggaggtgagc
    17761 aggagcatcg gccagtcggc gggcgaggcg gtcgcactcg gcaacctcgg cctcgtccac
    17821 tgggagatgg gccggctggc gcaggcggcg gagcactaca ccctggcgtt gaaccggcac
    17881 cggcagatca ggtcccgcta cggcgaggcg atcaacctcg gcaatctcgg tcacgtgcag
    17941 cgcctccgcg gtttgccggg tgaagcggcc cagctgctga tccgcgcgct cgccctgcac
    18001 cgcgagggcg gcaaccgcag cagcgaggcc cagacacgca gcaggctcgc cgcgacgtac
    18061 ctcgacctcg gccgtggccg ggaggcactg gagttcgccc gcaccggcct cgtccaggcg
    18121 caggagaccg gtgatccccg gatcgaggtg gaggcactcg ccgtgctggc caccgcggac
    18181 caccggctcg ggcaccgggc ggacgcgatc cgccactacc gccaggcact cgacctcgtg
    18241 cgcaacaccg gagaccggta cccggagatc gagatcctca tcggcctggc gacggtcacc
    18301 tcggacgtcg agcatgcgag gcatgcgctc gacctcgccg aacgcggggg ctaccgcgcg
    18361 ttgcaaggtc aggcgatggc cgctctcgcc ggcatcctgc tggcgtccgg gaaaccgcgc
    18421 gacagcgcga gccacgcgtc gcgcgcgctc gagatccacc gggagaccgg ccatcgccag
    18481 gccgaagcgt tcacgctcgc cgtgctggag cgggcgggcg ggtgactact ccacgatccg
    18541 gtcgccgatt cccttctccg ggatgtgact ggcgccgttc ggctggatga tgatcttggc
    18601 ccacggtgtc acgctcgccg gcctgccggc ggagtccttg caggagaact cggacatgtt
    18661 gaacgtctcc caggctccgt cgccgttcgg cacgggcttc tcgtactcct ccgcgttggt
    18721 cacccagacg cacgtggtgc cgtctgcctc gtgtgtgacg tgcggcgtga tgaaggtgat
    18781 ccgtccttcg tccacgcacc aggagacctg gtaggtgtag ctccatttgc cgggttcggc
    18841 gagccgcacc gtctcggagg tcagcagcgg cgtctcgcac ttctcctcgg ccgcctgggc
    18901 cgtggtgatc ggcagcccgg cgaagaggac gaccgcacat ccgatgatcg tcgctttcat
    18961 cgtgttcccc ctcgaaatcg tgtgcttcca atgtggtgcc tgcaaccgga tgtccgcaag
    19021 ggaggtccaa cccgcgtcca atcgacgtcc agtcgtgccg aatagcttgt gccgcagggt
    19081 tttccaacag gggaggaact gatgaaggcg cgaaccaaga ggggtgtcgc cgcggcggcc
    19141 gtcgtcgcct cggtggcggc ggccgtgatc ggtggcggcg ggagcagcgc tgctcagccg
    19201 tccggcctga gagcgttcgg gatctcggcg gacggcacgc tgatggtgac gttcacgacg
    19261 aacctgccgc aggagctgaa ctgggtgcgg cagatccagg gcttctcggg tgacaccgcg
    19321 gcgatcggcc tcgaccagcg cgtgcaggac ggcctgttgt acctggtggg caacaaggga
    19381 ggcatctaca cggtgaagct cccgaacccg ccctcgcagc cgaacccgat catcacgaag
    19441 gtgtcgcagc tgaccgtcgc gttgcacggc acgaacttcg gcgtcgactt caacccggcg
    19501 gccgaccggc tccgggtgac cagcgacacc gggcagaacc tgcgccacga cctcaacgcg
    19561 cacagcacgg tcgcggacac gatgctgtcc accccgccga cgccgggagc caccaagggt
    19621 gtcaccgcgg cggcctacac gaacaacgac ctggaccccg gcaccgcgac cacgctgttc
    19681 gacatcggca cgatgaccga ccaggtgctg atccagtcgc cggcgaacaa cggcacgctg
    19741 gctccgaccg gcagcctcac ggtggacgcc ggcagcaacg cgggcttcga catcttcagc
    19801 actctgtccg gcgggaaggc ggtgtccgtg gcgggcttcg ccactctcgt cgcaccgaac
    19861 ggcacgtcgt cgttgtacag catcaacctg ctcaacggga ccgcgaccag cctcgggcag
    19921 ttcccgctgc cgatcacgga cctggcgatc tcgctgaccg gaagctgaac actcccggcc
    19981 ggcagcgagc cccgtcccgg aacccgcccg tgttccggga cgggcgcggg ctgctgccgt
    20041 ccagccgacg tccagtcccc tggaatagct tgtgccccaa ggaatttggc acaggggagt
    20101 gggctgatga gggcacggat caagaaggct gccgccgcgg cggccgtggc ggtgtcggtg
    20161 gcggcggccg tggtcgccgg cgggaacagc agcgtcgcgc agccgtcggg actgagagcg
    20221 ttcggcattt cggcggacgg cacgctgatg gtcacgttca ccaccgatct gccgcaggag
    20281 ctgaactggg tgcggcagat ccagggcttc tcgggcgaca ccaccgcgat cggcctcgac
    20341 cagcgcgtac aggacggtct gctgtacctg gtgggcaaca agggaggcat ctacacggtc
    20401 aa
//
