LOCUS       NZ_MCIF01000002        32721 bp    DNA     linear   CON 09-NOV-2024
DEFINITION  Thermogemmatispora tikiterensis strain T81 A4R35_scaffold00002,
            whole genome shotgun sequence.
ACCESSION   NZ_MCIF01000002
VERSION     NZ_MCIF01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Thermogemmatispora tikiterensis
  ORGANISM  Thermogemmatispora tikiterensis
            Bacteria; Bacillati; Chloroflexota; Ktedonobacteria;
            Thermogemmatisporales; Thermogemmatisporaceae; Thermogemmatispora.
REFERENCE   1  (bases 1 to 5961682)
  AUTHORS   Tomazini,A., Lal,S., Stott,M., Henrissat,B., Polikarpov,I.,
            Sparling,R. and Levin,D.B.
  TITLE     Analysis of Carbohydrate Active Enzymes in Thermogemmatispora T81
            Reveals Carbohydrate Degradation Ability
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5961682)
  AUTHORS   Tomazini,A., Lal,S., Stott,M., Henrissat,B., Polikarpov,I.,
            Sparling,R. and Levin,D.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2016) Faculty of Agricultural and Food Sciences,
            University of Manitoba, 66 Chancellor's Circle, Winnipeg, Manitoba
            R3T 5V6, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-MAY-2011
            Assembly Method                   :: Newbler v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 25.9x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003268475.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 03:19:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,660
            CDSs (total)                      :: 4,607
            Genes (coding)                    :: 4,541
            CDSs (with protein)               :: 4,541
            Genes (RNA)                       :: 53
            rRNAs                             :: 2, 1 (5S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 8 of 66
            Pseudo Genes (incomplete)         :: 56 of 66
            Pseudo Genes (internal stop)      :: 6 of 66
            Pseudo Genes (multiple problems)  :: 4 of 66
            CRISPR Arrays                     :: 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:11:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2514678
            Orig. end                         :: 2547399
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MCIF01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..32721
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /product="RRE-containing"
                     /region_number="8"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..32721
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="neighbouring"
                     /product="azole-containing-RiPP"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..23534
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23534
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13534](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13534
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(707..2137)
                     /locus_tag="A4R35_RS10195"
                     /old_locus_tag="A4R35_10105"
     CDS             complement(707..2137)
                     /EC_number="7.5.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003542259.1"
                     /locus_tag="A4R35_RS10195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10105"
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="WP_262982325.1"
                     /transl_table=11
                     /translation="MSMSVFPGEVHALVGENGAGKSTLLKIMFGAYQPDRGTIEIQGRA
                     VILRSPATAIRYGLAMVHQEISLIPQLNAIQNIVLGWEASRLGLIDWADARVRASEALR
                     RLGFRANPMTPVGQLSVAQQQIIELARAVAMDARVIILDEPTATLSMQETEHLFAIIRE
                     LKASGHALVYVSHRLPEVFELADRVTVLRDGHLVGTLTRDENFTDATLIRMMVGRQPEV
                     QGTQSGTDTSSALAGEEILRVEGLTRNGIFHDISLTLRRGEVVGVAGMVGSGRTEVVRC
                     IAGADRADHGAIYVRGKHIHLRSPLDAIKVGIAFLPEDRKLQGLILGMSVATNITLPAL
                     PTRFGWISRRQQRDLAHAALRQIGTNLEVNRQVRQLSGGTQQKVVLAKWLVTGSDIFLF
                     DEPTRGIDIGAKAEIYRLMHQLKARGAAILMVSSELPEILRMSDRILVMRSGQIVAELQ
                     RSEASEEIIVMYASGGKP"
     gene            complement(2337..3248)
                     /locus_tag="A4R35_RS10200"
                     /old_locus_tag="A4R35_10110"
     CDS             complement(2337..3248)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF024799.5"
                     /locus_tag="A4R35_RS10200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10110"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_189361628.1"
                     /transl_table=11
                     /translation="MATSMGPVTAPKQLRFGVILKSLTNQYWQQIERGVETAAQRYGVQ
                     VTVQAASSESSPTQQLTIAQTMVGQRYDAYLVSPESVSNLTPALQSMQQQGVPIINVDD
                     ARVNATTFVGPDHELDGTEAAQYIAQRLPQGGDVAQIEGQAGSSAAILRIQGFKEGIAR
                     YRNLKLVASVPGNWDEATAYSDTQELLRKDPNLKAIYANNDTMAVGVAKAVADAGLKGK
                     IIIVGTDGIPQALDDIRSGLMSATVTPLPYYEGYWGVEAAVRLLAGQHVPDWIVAPAQL
                     ITADNISQFFNSNNEVRTDLYL"
     gene            complement(3505..5181)
                     /locus_tag="A4R35_RS10205"
                     /old_locus_tag="A4R35_10115"
     CDS             complement(3505..5181)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007288941.1"
                     /locus_tag="A4R35_RS10205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10115"
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="WP_112429015.1"
                     /transl_table=11
                     /translation="MSKVVSAAEAVQAIPDGAVLSVGGSGGGVLEPRALLVALEQRFKA
                     TGHPRDLTLVHCTGIGDRTAGGLTHLAHPGLIRRVIAGNWAMSHAMGQLALTNQIEAYN
                     FPQGVMAQLHREIAARRPGLVTHVGLHTFVDPRYEGGKMNSRTTEDLVEVVKLRGREYL
                     FYPAFPIDFAFIRGTTADEEGNLTFEQEGAVLDMLAIAQAAHNSGGRVIAQVKRLARAG
                     TLHPHHVVVPGIIVDQIVVVPGQWQTSEGEYHPAISGELKMPVDVIPRLPLNERKVVAR
                     RAFAELWPGAVVNLGVGMADGITAVAAEEGLLDRFVLTIEQGVIGGGPALGLIFGVAYN
                     PTAIIDQPAQFDFYDGGGLDIAFLGCAEIDRYGNVNVSKFGNRLVGTGGFIDISQNARK
                     IVFCGTLTAGNLLVNIRDGRLSVEREGTHRKFVENVEQVTFNAAYARARGQPVLYVTER
                     AVFELGDQGLVLTEIAPGVDLERDVLSHMAFRPAISPQLRIMDERYFLPGPVGYEVFVR
                     HTVDHHAVVRYTSRDIVETQPPAAFIQQRDHHDTDRKEGDS"
     gene            complement(5209..5973)
                     /locus_tag="A4R35_RS10210"
                     /old_locus_tag="A4R35_10120"
     CDS             complement(5209..5973)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (12-177). E-value: 3e-12. Score:
                     38.8. Matches aSDomain:
                     nrpspksdomains_A4R35_RS10210_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007424651.1"
                     /locus_tag="A4R35_RS10210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10120"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_223258284.1"
                     /sec_met_domain="adh_short (E-value: 4e-34, bitscore:
                     116.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 6.8e-32, bitscore:
                     109.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRENLFNLQDRIALITGAARGVGRAITLALAEAGADVAVNDLRAG
                     PELDEVVREVIQRGRQALPVVANVAVPEEVARMVTTVLDYFGRIDILINNAGIMTEIPF
                     LELAIEQWDQIIDVDLRGVFLCTRAVLPHMVERRQGVVINISSQLGQKGAPALAHYCAA
                     KGGVLALTRALAREFGPYGIRVNAVAPGPLDTEMTRPYATPAWLANKMAQSVLGRLGKP
                     EEVAPTVVFLASDAASLYTGQTLYPNGGGVML"
     aSDomain        complement(5443..5937)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R35_RS10210_PKS_KR.1"
                     /evalue="3.00E-12"
                     /label="A4R35_RS10210_PKS_KR.1"
                     /locus_tag="A4R35_RS10210"
                     /protein_end="177"
                     /protein_start="12"
                     /score="38.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALITGAARGVGRAITLALAEAGADVAVNDLRAGPELDEVVREVIQ
                     RGRQALPVVANVAVPEEVARMVTTVLDYFGRIDILINNAGIMTEIPFLELAIEQWDQII
                     DVDLRGVFLCTRAVLPHMVERRQGVVINISSQLGQKGAPALAHYCAAKGGVLALTRALA
                     RE"
     CDS_motif       complement(5446..5577)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R35_RS10210_0002"
                     /evalue="2.70E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="A4R35_RS10210"
                     /protein_end="176"
                     /protein_start="132"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="HMVERRQGVVINISSQLGQKGAPALAHYCAAKGGVLALTRALAR"
     CDS_motif       complement(5869..5934)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R35_RS10210_0001"
                     /evalue="7.90E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="A4R35_RS10210"
                     /protein_end="35"
                     /protein_start="13"
                     /score="15.3"
                     /tool="antismash"
                     /translation="LITGAARGVGRAITLALAEAGA"
     gene            complement(5970..6374)
                     /locus_tag="A4R35_RS10215"
                     /old_locus_tag="A4R35_10125"
     CDS             complement(5970..6374)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MannoseP_isomer"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF028177.5"
                     /locus_tag="A4R35_RS10215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10125"
                     /product="dimethylsulfonioproprionate lyase family protein"
                     /protein_id="WP_112429019.1"
                     /sec_met_domain="MannoseP_isomer (E-value: 3.9e-09,
                     bitscore: 34.6, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVCYLDKVAGEHFPSGRWTRLLAGVTSPIQPDQFVIGYSVIDPG
                     GGIPAHHHVNEEVYVLLSGTGRMMVGDEQAILSGVVAVYIPPNMTHQLTNVGDQSLHLL
                     FIYAPPGIMEHWQAERSGQLAMQHERGVGQ"
     misc_feature    6394..6404
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(6401..7459)
                     /locus_tag="A4R35_RS10220"
                     /old_locus_tag="A4R35_10130"
     CDS             complement(6401..7459)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012742.5"
                     /locus_tag="A4R35_RS10220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10130"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_112429021.1"
                     /transl_table=11
                     /translation="MRVTIKDVAREAGVSKATVSKYLNNAPYVSEHTRQLIEAAIRKLD
                     FQPNSTARGLRNHRSHCIGVIVASILNPFYPQLIQGIEDVATARGYALLLASSDGDARQ
                     EHQIVQAMRQRQVEGIIFASVRLTDREVLKLKRMHTHVILASRHLPDAPVDYVIVDSYK
                     GAYLAVEHLLMHGHRRIAHIGGPENIAQFADRMRGYSKALEDAGLDVDPTLVIRGGLRL
                     EDGELAFRQLMALANPPTAIFAATDNLAFGVLRAARASGCLIPEQLALVGFDNVPFSDI
                     AAPPLTTVDGNALGIGRHAASLLIDRIESAQGSSTAESDHTAAPDPMHLLFEPQLLIRQ
                     SCGCQTTEQIRR"
     misc_feature    7560..7571
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.03"
                     /tool="antismash"
     gene            7820..7951
                     /locus_tag="A4R35_RS24680"
                     /old_locus_tag="A4R35_10135"
     CDS             7820..7951
                     /EC_number="2.1.-.-"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R35_RS24680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R35_10135"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_146747172.1"
                     /transl_table=11
                     /translation="MQSYDILPAQHRILDLTCGPDGWDLELAFHFPNAHVLGVDINP"
     gene            7952..>8286
                     /locus_tag="A4R35_RS24255"
                     /old_locus_tag="A4R35_10140"
     CDS             7952..>8286
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R35_RS24255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R35_10140"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_189361629.1"
                     /transl_table=11
                     /translation="MIEYARTQAWSRGLEHIHFQVLNVMEPLAFPDGEFDLINGRLLSE
                     CYRLLTPGGVLHLTEVEPPPTTSPVFERHSALESEALRRAGQSWSPDGRHIGITPVLPR
                     LVRQAGF"
     assembly_gap    8287..8655
                     /estimated_length=369
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            9578..9772
                     /locus_tag="A4R35_RS10235"
                     /old_locus_tag="A4R35_10145"
     CDS             9578..9772
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R35_RS10235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R35_10145"
                     /product="hypothetical protein"
                     /protein_id="WP_112429025.1"
                     /transl_table=11
                     /translation="MNIEVSGFSEHLTMNREDYLHPHELAEFTVAPGVCTSNGHGTSTS
                     TICCCSAAPALLVTDESAS"
     gene            10001..10990
                     /locus_tag="A4R35_RS10240"
                     /old_locus_tag="A4R35_10150"
     CDS             10001..10990
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.5"
                     /locus_tag="A4R35_RS10240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10150"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_112429027.1"
                     /sec_met_domain="PF00881 (E-value: 4.8e-17, bitscore: 60.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINSKASGQVKTKSQDPAQEAPVAQKGNALSLPFMVNSTVSVDR
                     CADATGFRTPSLRHRSLSVSHDQRVAETFLLNTRLCRHDHESEAGVQLYYTDTVTYMLA
                     NNGIETFDTTLIIPLPPPARLRLSLGDCLLRRRSRRLFTGDPVRLEGLSSLLFAAAGIT
                     GIGKAPVEQGEHTVDLFFRTTPSPGGLYGVDLYVVALNISGLERGIYGYDPLRSRLALL
                     QGPDSVQAVLQAFAYPEEVISLSRACTLLIAIGRPWKVMRKYGSRGLRYLFIEVGQLAE
                     NVHLACTALGYGDVDIAGFYDDDLNEALGLDGLAQTVLHTIAVGIPAE"
     misc_feature    complement(10027..10042)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.6"
                     /tool="antismash"
     gene            11045..12142
                     /locus_tag="A4R35_RS10245"
                     /old_locus_tag="A4R35_10155"
     CDS             11045..12142
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03882.1"
                     /locus_tag="A4R35_RS10245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10155"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_112429029.1"
                     /transl_table=11
                     /translation="MFETEDCPRLKPHFSLIAHSENIVELRSGVWNPVSVTLKDRSNQG
                     KLLQALRRLDGQTTLKELARELDVPVQDLLQICASLDEFGALERGPTNVLDYYAALLAT
                     SLARPSTPQSALRTKQPEPILVLGHGEFAQRVLQELQASLNSPVSLIEEAELLQELSEQ
                     DLTEHEDGLASMQTAVRFTRWRDHFLVVALDVIDPILLRNLNVIATELGLRWLHSAIDG
                     PFLLIGPTIIPQRTPCYACFESRVGLNLREHASYVAYKQALVAGKVQPGRPVLLRPLYS
                     LAASLTALETLNNVLTGSAFTAGKVLSLYLPTMEFAFNEILRLPNCRICVPRTERYQKP
                     LYFDTRAYMNQIQLHLEEHPHGRRQ"
     cand_cluster    12086..32721
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    12086..32721
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[22085:22721](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(22086..22721)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="2"
     assembly_gap    12212..12906
                     /estimated_length=695
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <12907..13534
                     /locus_tag="A4R35_RS10250"
                     /old_locus_tag="A4R35_10160"
     CDS             <12909..13534
                     /codon_start=2
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014661.5"
                     /locus_tag="A4R35_RS10250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10160"
                     /product="YcaO-like family protein"
                     /protein_id="WP_189361631.1"
                     /sec_met_domain="YcaO (E-value: 1.3e-15, bitscore: 56.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="QILKRDAPRNSVTIRFYYLTNADMQAHVVAAVIWNNRGHVPACGI
                     GISAELNLELAMYKAYLEAAAIPHLALMAFVEMTSATKGNGIDPTAIYNLDTNVMYYAY
                     PEHRRLIEEKFTSSQRIKASELPADHQGGAEEGLQRVLNEFRRTGKRLALLDLSSPEIE
                     DLHFHVFRFYSPDTLGLCLPSAPQLAHRRYQAYGGATHERPHPYP"
     gene            13509..14315
                     /locus_tag="A4R35_RS10255"
                     /old_locus_tag="A4R35_10165"
     CDS             13509..14315
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014566.5"
                     /locus_tag="A4R35_RS10255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10165"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_189361633.1"
                     /sec_met_domain="Abi (E-value: 2.6e-09, bitscore: 35.5,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGLIPIPELETSLLAALLLLHASPVMLANRLAALLEPIRRVSPL
                     WLYVVVLGMLIGGDLVLISPDLHRIAWPTQALAVIVGLLGGELGFWLDQVVTTLLRKAS
                     RDTSRPLRRLPPILGPSPSWGAVLSLNPLQAADATGSTVTRTLLTRGEFLPPLVVAVGI
                     LEEIAYRWAFPWLLGFVLPWRELPGLLCGLMIANLFYGLIHLSFGSRTIFTRWLLGLLF
                     AALVLMSGSVLAASIAHGLFNWLAMKATLAERRRPITFVRSHPGGF"
     gene            14315..15094
                     /locus_tag="A4R35_RS10260"
                     /old_locus_tag="A4R35_10170"
     CDS             14315..15094
                     /EC_number="3.4.26.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014566.5"
                     /locus_tag="A4R35_RS10260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10170"
                     /product="type II CAAX prenyl endopeptidase Rce1 family
                     protein"
                     /protein_id="WP_112429033.1"
                     /sec_met_domain="Abi (E-value: 2.8e-06, bitscore: 25.7,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPTPLAALSALGWILAALLLQYVLCRRLIMATARHLAEQLPLSF
                     HYPTRDVALTLAVAGAGLTALGIAWAVSWANGENLLSLFTEHLLPLQLPIGILLGLGEA
                     SVSMLLSSLALAVFRPWRQRQIGPDLINELRTIGRAGWVRAYRQTLQIWPAPLGWASIA
                     LALLGEELLFRGLAVRLLAPEGFPFALVASTFLFVAVQAQGMPSWFSALPAMCGALVIG
                     PINAWLFMTVPNILPLEIAHLTFFCSHDFIISPLRCS"
     gene            15134..16102
                     /locus_tag="A4R35_RS10265"
                     /old_locus_tag="A4R35_10175"
     CDS             15134..16102
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="A4R35_RS10265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10175"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_112429035.1"
                     /transl_table=11
                     /translation="MAETLERRRMSMEVSAEPAVTQFRQPVILLDQVTKYYGNVQALRG
                     VSLRIEAGESVALLGPNGAGKTTAISLMLGLLRPSTGHVLLNGGDPTIPAVRRAARLGA
                     MLQNARVIDLVRVRELLDVFRSYYDHSLPTDELLEIAQLHDKQHSYTQHLSGGELQRLL
                     FALALAGDPRILFLDEPTAGMDVASRRRFLQCIRELHRDGRTIILTTHNLAEVEGLSQR
                     VIVLNEGRIVADDSSEAIRATASGQFVSFLAEEQTDQLLAAIPGVLRIERQGPRVVLLT
                     RDSDALLKDLQRQGIATPHLEIRGASLEEAFLALTRKEEQT"
     gene            16099..16842
                     /locus_tag="A4R35_RS10270"
                     /old_locus_tag="A4R35_10180"
     CDS             16099..16842
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.5"
                     /locus_tag="A4R35_RS10270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10180"
                     /product="ABC transporter permease"
                     /protein_id="WP_112429037.1"
                     /transl_table=11
                     /translation="MTLLALRAQSKLELLRFLRNVRALFFTLLVPIGYYLIFSYGFGNT
                     HDLQLHFGIAMAGFGTLGVSLGTLGSRLAQERQLGWLRLLQTTPLTPLTYFVAKVIATF
                     SMAGLTIIGVLTVALLEGLRVDNYWALVTSALILWGGSLPFIALAFVIGSWTDAETGYV
                     VSIGVYLVLGYLGGLLQPLQFMPSVLQDVARWLPSTHYFLLALRPLQAASSGSALEDVL
                     ILLVYTLLFTALAIWSYRRAGTADR"
     gene            complement(16873..18009)
                     /locus_tag="A4R35_RS24685"
                     /old_locus_tag="A4R35_10185"
     CDS             complement(16873..18009)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="A4R35_RS24685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10185"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_223258285.1"
                     /transl_table=11
                     /translation="MSGQNTMTTSESCLQLRHCYMLTLLRAIAGIGTLLSLQVTPSPLA
                     FWAIALGITFCLWAFLTFLVVCYWRTQARRLWPLALAIDLALCVAVNLLFAPLPSSLAA
                     AAFLLPAYGWAIAYGVVGALIVLLTFCWSELIIALLRLSTNQPPASWLSMLLWFLVISL
                     TAGLHLLLRRRRHLLAFIFSNQSNSPLQLGSPAFQLSESLRPEATENRESASLQSSLSL
                     SPYCGPNVTLASGSPLIHDTLPGVQVPVLLAALETAFAAYGVKLDQHRQRLESALEALK
                     HPHMADPAQFACCLRCLLQEAEYNWQQRAALSAREWELLNLLAEGLSYRQIGQRLYLSP
                     STVKTHMRNLQQKLGVSGKEKMLRLARARGWIKDQARQ"
     gene            complement(18684..19037)
                     /locus_tag="A4R35_RS10280"
                     /old_locus_tag="A4R35_10190"
     CDS             complement(18684..19037)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Methyltransf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013315.5"
                     /locus_tag="A4R35_RS10280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10190"
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="WP_112429039.1"
                     /sec_met_domain="PCMT (E-value: 4.1e-26, bitscore: 90.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="Methyltransf_3 (E-value: 1.4e-07,
                     bitscore: 29.1, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLVTRLREGLPVSSSSAPTAMARLLEVQPGQRVLEIGTGTGSNA
                     ALLAELVGPTGQVWTVEVEEELAEQARTRLQAAGYGARVEVVATDGWQGETPAAPYERL
                     LATASVPGIPRRW"
     gene            complement(19044..19169)
                     /locus_tag="A4R35_RS24990"
     CDS             complement(19044..19169)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R35_RS24990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_262982326.1"
                     /transl_table=11
                     /translation="MMTFDTPVPSAGHPRRWQRCEAGQGQGQEAQEQWAAWVEAI"
     gene            complement(19275..19679)
                     /locus_tag="A4R35_RS10285"
                     /old_locus_tag="A4R35_10195"
     CDS             complement(19275..19679)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R35_RS10285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R35_10195"
                     /product="hypothetical protein"
                     /protein_id="WP_146747174.1"
                     /transl_table=11
                     /translation="MAERYALQFREVAGDELLSEEEALDPTPYRPFLAPWEHESPYRDF
                     EIARARLARVVSREPGQPLNRKPFVIETPHGQALLWRAIPGKVEVVLCLQQPGGQWVLQ
                     ADQVVTLSEEEWQSCRIRLDRIVVNPPPWL"
     gene            complement(19733..19987)
                     /locus_tag="A4R35_RS10290"
                     /old_locus_tag="A4R35_10200"
     CDS             complement(19733..19987)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R35_RS10290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R35_10200"
                     /product="hypothetical protein"
                     /protein_id="WP_112429043.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFPWLQPAPFPPHEPKGEAAALAGDPLLVEIGSVVQLTRGKGDD
                     DYDAPAAGYFDVPDPPPEPGGDDEGEERPSPDEEDEDEE"
     gene            complement(20019..20978)
                     /locus_tag="A4R35_RS10295"
                     /old_locus_tag="A4R35_10205"
     CDS             complement(20019..20978)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="A4R35_RS10295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10205"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_317615974.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.2e-09, bitscore:
                     35.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLTAVLFFGSWYRCLGQLARSRRVRMYLRGTFGDALWDPAWRTM
                     LRECWQEHALGIVWQTLWLWHRQGMSWGQILLTRGSPLWRSTEAPWHRRPLAPWLRPEV
                     WQRVLAVEEAERQRCRQRGPVQVWEWLRWIDRFAETAALAAARPLVEAGLTSTDPYTDP
                     RVIEQVLAIPLTLIAPHGQPPKGLLREAMRGHLPEPVRVRATKGRIARAIFRALWERRG
                     WLQDELRAGPGELDPYLDRECLRVQLDRLPFLTVTQPIVLSSLALALWVRQGGAAGGGP
                     EAVARLPAAPVGLLGNGRGKTGRQTGASGADQLIQWME"
     misc_feature    complement(21098..21113)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.7"
                     /tool="antismash"
     gene            complement(21212..21898)
                     /locus_tag="A4R35_RS10300"
                     /old_locus_tag="A4R35_10215"
     CDS             complement(21212..21898)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024927.5"
                     /locus_tag="A4R35_RS10300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10215"
                     /product="hypothetical protein"
                     /protein_id="WP_112429047.1"
                     /sec_met_domain="GATase_7 (E-value: 5.8e-16, bitscore:
                     56.6, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGFCLWASLDPDPPEAETPIDATRWLQIGALVRQRGDQLFSWRS
                     HGCWCWQALEHEACPRSWGSCRSLWVAADGRLYYRSALLEALRVHHAVPARLSDLEYLA
                     WSYRCWGEENLRRLEGDYACVWWDEERRLGLAARSPFGLRPLFYQVWGQTLILASDPAW
                     LLQATNGPCDLDADWVCWYLATGHFRSASPWRTVHEVPPGGWLRWQAGQLQTGLFWSPR
                     RKTDLL"
     gene            complement(21895..22089)
                     /locus_tag="A4R35_RS25290"
                     /old_locus_tag="A4R35_10220"
     CDS             complement(21895..22089)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="A4R35_RS25290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10220"
                     /product="hypothetical protein"
                     /protein_id="WP_223258286.1"
                     /transl_table=11
                     /translation="MSAHVVLGVSTAPFTAHAWVEGPDGPLFWKAGLGWLAHRAMLAGL
                     QPIFHSGRDLLQSRKEELR"
     gene            complement(22086..22721)
                     /locus_tag="A4R35_RS24270"
                     /old_locus_tag="A4R35_10225"
     CDS             complement(22086..22721)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R35_RS24270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R35_10225"
                     /product="PqqD family protein"
                     /protein_id="WP_189362316.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.6e-08,
                     bitscore: 32.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCAAEVRRQAEQTGVASPGQRAAVPLPLIFATPTAEGGVLLDLCR
                     GRYLGLTPRGWSLWEALQVGKRGQELVSVLQQQGIGEEEAKEAVCRFEQEMVRLALHDP
                     ELPRPRRGISSFLLWVLRCCPSCWEPLDAWLTLGGIRWLLRRADGLLLVIAVGQTLQGT
                     ASDQMGRAARPLVRDLCRWVRRVSLVQRRHPRAWSKVLRSGGSFASGG"
     aSDomain        complement(22431..22631)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_A4R35_RS24270_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="9.90E-11"
                     /identifier="RREFam002.1"
                     /label="A4R35_RS24270"
                     /locus_tag="A4R35_RS24270"
                     /protein_end="97"
                     /protein_start="30"
                     /score="32.5"
                     /tool="antismash"
                     /translation="ATPTAEGGVLLDLCRGRYLGLTPRGWSLWEALQVGKRGQELVSVL
                     QQQGIGEEEAKEAVCRFEQEMV"
     gene            complement(22781..22969)
                     /locus_tag="A4R35_RS10310"
                     /old_locus_tag="A4R35_10230"
     CDS             complement(22781..22969)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R35_RS10310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R35_10230"
                     /product="hypothetical protein"
                     /protein_id="WP_146747176.1"
                     /transl_table=11
                     /translation="MGTALALDLVEPLRQIESQVNLARLQQLTERLSASPFGDAPEVAR
                     LRALLEGPRRGKPGPTP"
     misc_feature    complement(23000..23009)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    complement(23319..23334)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            23561..23851
                     /locus_tag="A4R35_RS10315"
                     /old_locus_tag="A4R35_10235"
     CDS             23561..23851
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R35_RS10315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R35_10235"
                     /product="hypothetical protein"
                     /protein_id="WP_223258287.1"
                     /transl_table=11
                     /translation="MVAHAPLGFRSARRRFEDMPFFLPKDQQELNRLDSQHAVLRQVFR
                     DSVLAPVQDLLHEGTVVLDVGISPSRWAFEREAPGETSLPSCLSCATAVSS"
     assembly_gap    23992..27019
                     /estimated_length=3028
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            27430..27903
                     /locus_tag="A4R35_RS10325"
                     /old_locus_tag="A4R35_10245"
     CDS             27430..27903
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R35_RS10325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R35_10245"
                     /product="hypothetical protein"
                     /protein_id="WP_112429057.1"
                     /transl_table=11
                     /translation="MAFWRHLFRRRRRVQAASAAPAVVMTAAAVSTAPEYGHSSPFAQR
                     RYLEDVPSLFPKDPLEDQRLNYQHHALYRTLSNHYLAPLAPERTRTILDVGTGIWAFQR
                     QALFPHALCSTASPASAASSASSWPSCAGWARSCRQQADGPPRSRSPRGPSLL"
     gene            28352..28969
                     /locus_tag="A4R35_RS10330"
                     /old_locus_tag="A4R35_10250"
     CDS             28352..28969
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010241008.1"
                     /locus_tag="A4R35_RS10330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10250"
                     /product="HD domain-containing protein"
                     /protein_id="WP_112429059.1"
                     /transl_table=11
                     /translation="MAESLSLSAKEVLALPNQALLVSFARLAEELLSPLGARWLHVQGV
                     ARVALRISPLFAPDDAWHLIAAAYLHDVGYAPALWHTGFHPVDGALFLRQQGYERLACL
                     VAHHSEARFEAHLRGLEDLLSRFPRERSVVADALTFCDLTTSPLGTRVSLQERAREVTL
                     RYGPDHLVTQALRQALPTKALAIARTRRWLQRHGLDPDHLTE"
     gene            complement(28959..29426)
                     /locus_tag="A4R35_RS10335"
                     /old_locus_tag="A4R35_10255"
     CDS             complement(28959..29426)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000864.1"
                     /locus_tag="A4R35_RS10335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4R35_10255"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_112429061.1"
                     /transl_table=11
                     /translation="MRIDYYDDPAAPKANAIVPAAWAIIEDEEGRILLQQRQEDGLWSL
                     PGGAMELGESITQTLLREVKEETGLDVLPEYLVGIYSDPRHVIALDHGEVRQQFSLCFA
                     CRVIGGSLQISSESRDLRFFSVSELDRLPMHRSSLLRIKDYQHYCGHPFIR"
     gene            complement(29440..30195)
                     /locus_tag="A4R35_RS10340"
                     /old_locus_tag="A4R35_10260"
     CDS             complement(29440..30195)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R35_RS10340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R35_10260"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_146747177.1"
                     /transl_table=11
                     /translation="MENERLRSAMESAHLDVETLAERVNVDPKTVRRWLHGCLPHPRHR
                     WKVSELLQLPEKSLWPLKGNASSSSDCTAEMLAAYAHRSDVPPEAWWRLFVKAEKHIDL
                     LGIALLFLPEQHPYLVELLKEKASTGCQVRIALAHPDSVALRMRDGEEYPGTLPPRIQT
                     TLYHFRDILHHDGIQIRFHSTVLYISYARFDDEMFVMPQLFRLHGSKAPLLHLRSLIPG
                     GIFANFAAHFEAVWETTTPLEAIEGCHSA"
     gene            30552..>31079
                     /locus_tag="A4R35_RS24275"
                     /old_locus_tag="A4R35_10265"
     CDS             30552..>31079
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R35_RS24275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4R35_10265"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_189361637.1"
                     /transl_table=11
                     /translation="MAFWRHLFPRRRARARSVSSPAVPTVVTSTAAVSTAPEHGHSSPF
                     AQRRYLDDVPYLLPKDPLEDQRLNYQHHALYRTLSNHYLAPLTPESIRTILDVGTGTGI
                     WAFEMQALFPHALVVGVDVSLQSLPQPVPPTCVFVRANVLEGLPFPDGQFCYTHQRLLV
                     AAIPAQAWPGVVR"
ORIGIN
        1 ccgagtttgg tgtactttaa ggtcgccgct gccaggagta acacagcgag cagcaccagt
       61 acaggtattg gaatcggacc gagagaaccc ccaaggagtc cttcgaatga gagaggaata
      121 ccgtagaccg tttggccgcc tgcgaggatg agggcaatgc ctgcatagat gctcatagtg
      181 cccagggtag cgatgaaggg agtgatccgg atgagcgtaa taatcagacc gttcaccaga
      241 ccggccagag cgccaatgat cagcggcccg atcagcgcaa tagcaaacga ggtcccgtga
      301 atcaacagca gcccagcgga aacagcggag acagccagga tcgagccagc ggataagtca
      361 atgccggcag taatgatgac aaacgtttcg ccaagtgcga gaagacctgt gaccactgat
      421 tgcagaatga tattgatgat attgtaacta ctcaggaatc taggacttaa agctgtaaag
      481 accaggaaca ggacaacctc ggctaccaca atgccggtct ggcgatacgt gccgatgcgc
      541 gctgcctggc gcaatgcacg gctgagcact tctgctggtc ctcgctgggt accaagcccc
      601 tctgtagcag gagtctgcgt tgactccgtc tggctcacct ggtgtcgtcg cccgtcgtgg
      661 cgatactttt caacgggctc cgtctgatgt aacatgcgcc gttccttcat ggtttgcctc
      721 cgctcgcata catcacgatt atctcttccg atgcttcgct gcgctgcagc tctgccacga
      781 tctgtcctga ccgcatcacc aggatgcggt cgctcatgcg caagatctca ggtagttccg
      841 aggagaccat caagatcgct gctccccggg ctttcagctg gtgcatcagg cgataaatct
      901 ctgccttagc acctatgtcg atgccgcgtg tgggttcgtc gaagagaaag atgtcgctgc
      961 cagtcaccag ccatttcgcc aacactacct tttgctgcgt accgccgctc agctgacgga
     1021 cttggcggtt gacctccagg ttcgtaccaa tctgccggag cgcggcatgg gctagatccc
     1081 gttgctgtcg acgactgatc catccgaacc gagtggggag agctggtagg gtgatattgg
     1141 tagcaaccga cattcctagt atcaagcctt gaagcttacg gtcctcagga aggaaagcaa
     1201 tgcccacctt gatcgcatcc aagggagaac gcagatgtat gtgctttccc cgcacataga
     1261 tagcgccgtg atcagcacga tcagccccag caatgcaccg cacgacctct gttctcccgg
     1321 atccaaccat accggcaacc cccacgacct ccccccgacg tagcgtcagg ctaatatcat
     1381 gaaagatgcc gttacgcgtg agtccttcaa cgcgcagaat ctcttcaccg gccagagcag
     1441 acgaagtatc tgtacccgac tgagtaccct gcacctctgg ctgacggcct accatcatac
     1501 gaatgagcgt agcatccgtg aagttctcat cgcgcgtcag ggtgccaacc agatgaccat
     1561 cgcgcaggac cgttacacga tcggcaagct cgaagacttc agggaggcga tgcgatacgt
     1621 acaccagtgc atgaccgctc gccttaagtt cgcgaatgat ggcaaagaga tgttcggtct
     1681 cctgcatgct gagcgtagcc gtaggctcat ccaggatgat aacccgtgca tccatagcaa
     1741 cagcacgggc caactcgatg atctgctgct gtgctacgct cagctgtccc accggggtca
     1801 tgggattcgc tcggaagcca agccggcgca aagcctcgct ggctcggacg cgagcatccg
     1861 cccagtcgat gaggcccagg cgacttgctt cccaacccag cacaatgttt tgaattgcat
     1921 tgagctgagg aatgaggctg atttcttgat gcaccatggc taggccatag cggatagccg
     1981 tcgccgggct acggagaata accgcccttc cctgaatctc aatcgtccct cgatccggct
     2041 ggtaggcccc aaacatgatt ttgaggagag tcgacttgcc ggcaccgttc tcccccacca
     2101 gcgcgtgtac ttcgccgggg aacacagaca tgctcacgtc ccggagcgcc tgagtcccag
     2161 gaaagtgctt ccatatacct cggagttgca gtagtggagt ggttgtcacg attctgcccc
     2221 cttgctctcc gccatccaga gcgatcctcc agcactggga cagagaaata ctcagtggcc
     2281 ccagtgctgg ttaaagcgct aactgcacgc tggcgaagac agctcaggct gtctcgctac
     2341 aggtagaggt cagtcctgac ctcgttgttg ctgttgaaga actggctgat attgtcagca
     2401 gtaattagct gagcaggcgc aacaatccag tcaggcacgt gttgcccggc aagcagccga
     2461 acagctgctt cgacccccca gtagccctca tagtaaggaa gcggagttac cgtggcggac
     2521 atcagcccgc tacggatatc atcgagtgct tgtggtatgc catcggtgcc gacgatgata
     2581 atcttcccct tcagaccagc gtcagcgacg gctttggcaa cgcccacggc catcgtatcg
     2641 ttgttagcat agatggcctt cagattcgga tccttacgca gaagttcctg ggtatcactg
     2701 tatgctgtag cttcatccca gttgccaggc acgctggcta ctaacttgag attacgatac
     2761 cgggcaatcc cctctttgaa cccctggatg cgcaagatcg ctgcactaga tcccgcctgc
     2821 ccttcgattt gagctacatc acccccttgg ggcaagcgct gagcaatgta ttgggcggcc
     2881 tcggtcccat ccagctcgtg atcgggtccc acaaaggtgg tagcgttcac acgagcatca
     2941 tccacattga tgatgggaac cccttgctgc tgcatacttt gcaatgcagg agtcaaatta
     3001 gagacggact caggggaaac caaatatgcg tcgtagcgtt gtccaaccat tgtctgagca
     3061 atggtcagct gctgagtcgg cgacgactct gaactcgccg cctggacggt cacctggact
     3121 ccgtagcgct gagcggcggt ctcgacccct cgttcgatct gctgccaata ctgattagtt
     3181 agactcttga ggatcacccc gaagcgtagc tgtttgggtg ctgtcaccgg acccatcgag
     3241 gtggccaagt cagcaccctg gatttttgtc gctgcaggag aggccgagtg ataggtatac
     3301 gtcctcgagg acgaagcgga cggcgaggag ctctcgccac atcctgtgaa cgctatagct
     3361 gctcccatga gcagtgcgat aaccagccta accgtgtatg gcgtatttct ccacatggca
     3421 agtttctctc attcattgag actactgaac gacgcctacg atccgcagct ggcaactgca
     3481 tctagcctag ttagcagaac ctgcttagct gtccccctcc tttctatccg tgtcatgatg
     3541 atctctctgc tggataaatg ccgccggcgg ctgcgtctca acgatatcac gagaggtata
     3601 acgtacaacc gcatgatggt caaccgtatg gcggacaaag acttcatagc ccaccggccc
     3661 tgggagaaag tagcgttcat ccatgatgcg gagctgagga gagatagcag gacgaaaggc
     3721 catatgagaa aggacatctc gctcgagatc gacgccaggc gcgatttcag tcagcaccag
     3781 gccttgatcc cccagctcaa ataccgcgcg ttcggttaca tacaaaactg gttgaccgcg
     3841 tgctcgcgca taggcagcgt taaatgtcac ctgttcgacg ttctcgacga atttgcgatg
     3901 ggtcccttct cgctcaactg atagacggcc atcccggata ttaacgagca agttacccgc
     3961 tgtcagtgtt ccgcagaaga cgatcttgcg cgcattctgc gaaatatcta tgaagccccc
     4021 cgttcctacc aacctgttgc caaatttact gacattcaca ttgccataac gatcgatctc
     4081 cgcgcacccc agaaaggcga tatccaaacc accaccatcg taaaagtcga attgtgctgg
     4141 ctggtcgata atagctgtcg gattgtatgc aacgccgaaa atcagaccca gagctggccc
     4201 acctccaata accccttgtt cgatggtcag cacgaaacgg tcgagtagac cctcttctgc
     4261 tgctacagcc gttattccat cagccatacc cacacccagg tttactacag cacctggcca
     4321 taattccgca aacgctctcc gggccactac tttgcgttca tttaacggca gccggggaat
     4381 gacatcgaca ggcatcttca attccccgct aatagcagga tggtactcac cttcgctggt
     4441 ctgccactgc ccaggcacga ccacgatctg atcgacgatg attccaggca ctaccacatg
     4501 atgagggtgc aaagtccccg cccgggcaag ccgtttgacc tgagcgatca cccgcccccc
     4561 tgagttgtgc gctgcctggg caatagccag catatcaagc acagcccctt cctgctcaaa
     4621 agtcaaattg ccttcttcat cggctgtagt gccccgaata aaggcgaagt caataggaaa
     4681 cgccggataa aagagatact cacgaccccg cagcttcact acttctacca gatcctccgt
     4741 agtacggctg ttcatctttc ctccttcgta acgggggtca acaaaggtat gcaggccaac
     4801 gtgcgtcacc agcccggggc gcctcgccgc gatctcacgg tggagctgcg ccattactcc
     4861 ttgcgggaag ttgtaggcct cgatctgatt ggtcagcgcc agctgcccca tcgcgtggct
     4921 catggcccag ttcccggcga tcacccggcg aatcagcccc ggatgggcca gatgggtcag
     4981 cccccccgct gttcgatcac caatacccgt acaatggacc agggtaagat cccgagggtg
     5041 gcctgtcgct ttaaagcgct gctctagagc cacgagcaaa gcccgtggct ctaggacccc
     5101 cccacctgac cctccgacac tgagaaccgc cccatccggg atcgcctgca ctgcttcagc
     5161 tgctgaaact actttactca tccatcttct cctccggcct ggctgccctt agagcataac
     5221 tcccccgccg ttcggataca gtgtctgccc agtatagaga gaagcggcat ccgaagccag
     5281 aaacaccacc gttggtgcaa cctcctctgg cttccccagc cgtcccaaga cgctctgcgc
     5341 cattttattg gctaaccatg ccggtgtggc gtagggtcgc gtcatctctg tatccaatgg
     5401 ccctggggca acagcattca ctcgtatacc atatggcccg aattcgcggg caagagcacg
     5461 tgtgagagcc agcactcccc ctttcgcggc acaatagtga gccagggctg gcgctccctt
     5521 ctggcctaac tgggagctga tgttgatcac aaccccttgg cgccgctcga ccatgtgcgg
     5581 tagcactgcg cgagtgcaga gaaacacccc tcggagatcc acgtctataa tctgatccca
     5641 ctgctcgatc gccagctcaa gaaagggaat ttctgtcatg atcccagcgt tattaattag
     5701 aatatcgatg cgaccgaagt agtccagcac tgtagtgacc attctggcca cttcctcagg
     5761 aaccgcgaca ttggcgacca ccggcagagc ctgacgacca cgctggatta cttcacgaac
     5821 cacctcgtct agctcgggtc cagcccgcag gtcgttgacg gcaacatctg caccggcttc
     5881 ggccaacgcc aaggtaatcg ctcgccccac ccctcgggct gcgccggtga tcaaagcgat
     5941 gcgatcttgc agattgaaca aattctctct cactgtccca cccctcgctc atgttgcatc
     6001 gctagctggc cactgcgttc cgcctgccaa tgctccataa tccccggagg ggcatagata
     6061 aagagcagat ggagactctg atcaccgaca tttgtgagtt ggtgggtcat attaggcggg
     6121 atatagacgg cgactacgcc ggagaggatg gcctgctcgt ctcccaccat catacgtccc
     6181 gtgccagaaa gcagcacata aacctcctca ttcacatgat gatgcgctgg aatacctcca
     6241 ccagggtcta tgaccgagta accgataaca aactggtcag gctggatagg gctagtaact
     6301 ccagcaagca ggcgtgtcca gcgtccacta ggaaagtgtt caccggctac tttatccaga
     6361 tagcagactt gcatgtgcag acctccaggc ctctgaaatg tcaccgacgt atttgctcag
     6421 ttgtctggca gccacaagac tgccggatga gcaactgtgg ctcaaagagc agatgcatcg
     6481 ggtctggcgc ggcggtatgg tcggactcag cagtgctgga tccctgagca ctctcgatac
     6541 ggtcaatgag caaagacgct gcatgcctgc cgatacctag cgcgttacca tcaacggttg
     6601 tcagaggcgg tgcagcaata tcactaaatg gcacattatc gaagccgacc agagctaact
     6661 gctctgggat cagacagcca gaggcacggg cagcgcgaag cacaccgaaa gccagattat
     6721 cggtagcagc aaagatagct gtgggaggat tagcaagtgc catgagctgg cggaacgcta
     6781 gctccccgtc ctcaaggcgc aggcccccac ggatgacgag ggtcggatct acatcaaggc
     6841 cggcatcttc taatgccttg ctgtagccgc gcatgcggtc agcgaactga gctatgttct
     6901 cgggaccccc gatatgcgcg atacgccggt gaccatgcat caagaggtgc tctaccgcta
     6961 aataggctcc cttgtaactg tccacaataa cataatccac tggtgcatcg ggcagatgtc
     7021 ggctagctaa gatcacatgg gtatgcatac gcttgagctt tagcacttca cggtcggtta
     7081 gccgtaccga tgcaaagatg attccctcca cctgtcgctg gcgcatagcc tgcacgatct
     7141 gatgctcctg tctggcatct ccatcggaac tggcgagtaa cagggcataa cctcgtgctg
     7201 tagcgacatc ttcaataccc tggatgagct gtgggtagaa agggttcaag atactggcga
     7261 caatgacgcc aatgcaatgg ctccggtgat tgcggaggcc gcgagccgtg ctattaggct
     7321 gaaaatccag tttccgaatc gctgcctcaa tgagctgccg tgtgtgctcc gaaacgtaag
     7381 gtgcattatt caagtacttg gataccgtgg ctttggacac cccagcttct cgggctacgt
     7441 ccttgattgt caccctcaca atgaccgtct ccgtaatctg gtccttttag gaaaccgata
     7501 tcggccaata ataccggtat ggaacaagga ataagatctc ttactcaagc taagataggg
     7561 aaaccgttat ctgatacgga aggtagtgta cctgactata agctctttgt caaggggata
     7621 accagcatga atctgatgtg agatcggctc agaataggag gaaaatctag gaaaccggtt
     7681 tcctatctcg tcgcttcgtt ctcctcttct cgctgccgat gaggagaccg gctcggagtc
     7741 cttaccgcct ttcttgcatt tcctgagatt cgtacactct tgcttgaatg ttgttgaggc
     7801 tttctattca aatattccta tgcaatcata tgatatcctg cccgcgcagc accgcatcct
     7861 cgatttgacc tgtggccccg acggctggga cctggaactg gcctttcact tccccaacgc
     7921 gcacgtcctg ggggttgaca tcaaccccta ggtgatcgag tacgcccgca ctcaagcctg
     7981 gtcacgcggc ctggagcaca tccacttcca ggtactgaac gtcatggagc cgctggcctt
     8041 ccccgacggc gagttcgacc tgatcaatgg gcgactgctc tcagagtgtt atcggctgct
     8101 cacgccgggc ggggtcctcc acctgaccga ggtggagcct cccccgacca ctagtccagt
     8161 gttcgaacgc cacagcgcct tggagagtga ggccctgcgg cgagctggcc agagctggtc
     8221 gcccgatggc cggcacatcg gcatcacccc ggtgctgccc cggctggtgc gccaagcggg
     8281 ctttcannnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8641 nnnnnnnnnn nnnnntgacg gccacttttc caggagcttc ctccgcgact ggagcatagc
     8701 tgtcacacga gcatgcctgc cctgtcctgc gctgcagccc acccccacgc tgggccgttc
     8761 gcagcgctgg tgcccgtgac ccccgctgtt cagcgctgtc ccgctgatac agaccggggt
     8821 caccagctga tctgcagcca ggatagggca cgccagccca ttcacctgcc catcgactct
     8881 gctcctgacc tccttgctca gcccaccaca ggatggatca ggatcgcgct gactctggca
     8941 gcctggaaac gtcccccgcg gatgctcccc tgagactccc tgacccttcc tcgcatcaca
     9001 cacatccaag actactggct caagtcacca ggtcaggtct gcccagatat acctggctcc
     9061 tccgtgccgg tcagccctgt cagcacctcg tgccgcgagc acacagcgct gcatgctcct
     9121 tccatcagga ggtcgggact gagctgcact ggggcagctg gccggccccc gtcaacgtga
     9181 tccgaggtgt cagggcctgc cagggtgcac tcagcccacc ctcctgctcg ccttcgcgca
     9241 gtaccccatg acacggcgac tcctggcgat cctctcgcgc acgatcccga tccctgctct
     9301 ttggcttcct tcttcagcaa gtcctttgac ctcccggctc acaagccttc tctccttcag
     9361 ccacacgcta cgggtcgaaa gagattcaac ctgcctgctg gtcctggacg agggaaaacc
     9421 catcagcttt tgggcaccag gtgagataag attgaccagt ggacgatggt ttctcaacca
     9481 ctgcagatgc tatatccttg cgagggagag caagcagcct ctccctggta tccctttcca
     9541 ggagcactct ttgaagcaag ggggtcaatg aacagcgatg aacattgagg tgagcggatt
     9601 cagcgagcat ctcacaatga atcgcgagga ctatctgcat ccgcacgagc tggcagagtt
     9661 taccgtcgcg ccgggtgtct gtacttcgaa cggacacggg accagcacct cgacaatttg
     9721 ctgctgctca gcagctccgg cgttgctggt cactgatgag agcgccagct agtcctatct
     9781 gccaggctac catcttgttc gcctgatctg agactcctct ccgacgggaa gggggtctca
     9841 gatcagtgga gcatggaggc agagtaaaca aggaagcatg tctctggcct ccgagataga
     9901 gctatagcga aatgctgccc agatagtaga ttgggaagaa gtacacgtac caggtgcata
     9961 tggctgcgtt tcatagctca actgctgagg agcaacgaag atgaccatca acagcaaagc
    10021 ttcgggtcag gtcaagacca agagccaaga tccagctcag gaggcccctg tcgcccagaa
    10081 agggaatgcc ttgtccctgc cctttatggt caattccaca gtgagtgtcg atcgctgtgc
    10141 ggatgcaaca ggatttcgca ctccctcact gcgtcaccgt agcctgagtg tttcacatga
    10201 tcaacgtgtc gccgaaacct ttctgctgaa tacccgtttg tgccgtcacg accatgagtc
    10261 tgaagcgggt gtccagcttt actataccga taccgtgacc tatatgcttg ccaacaacgg
    10321 tatcgaaacc tttgatacca ctctcatcat tcctttacct ccacctgctc gcctgcgcct
    10381 cagcctgggt gactgtctgc tccgcaggcg cagccgacgc ctcttcactg gtgatcctgt
    10441 ccggctcgaa ggacttagtt ccttactctt cgctgcagcg gggattaccg ggatcggcaa
    10501 ggctccagtc gagcagggcg aacacacggt cgatctgttt tttcgtacaa ctccctcacc
    10561 gggaggtctc tatggcgtcg acctttacgt ggttgccctg aacatcagtg gactcgagcg
    10621 cggcatctac ggctacgatc cattgcggag cagactggcc ctgcttcagg gtccagacag
    10681 tgtacaggca gtgctccagg cctttgccta ccccgaagag gtgatctcgc tctcgcgtgc
    10741 ctgcaccctg ctgattgcca tcggacgccc ctggaaggtg atgcgcaagt atggcagtcg
    10801 cggcctgcgt tacctcttca tcgaggtcgg gcagcttgct gagaacgtcc acctggcctg
    10861 taccgccctc ggctatgggg acgtggatat tgcaggtttc tacgacgatg acctcaatga
    10921 ggctctgggc ctggatggtc tggctcaaac cgtgctgcac accatcgctg tcggcatccc
    10981 ggcagaatag agaccaagac gagcaaagaa atagaatatt tatctcatta aggagaattg
    11041 tctgatgttt gaaaccgagg actgtcccag actaaagcca cacttttctc ttattgcgca
    11101 tagcgagaac attgttgaac tgcgctcggg cgtctggaac ccggtctcgg tgactctcaa
    11161 agaccgcagc aatcaaggca agcttcttca ggctctgcgg cgccttgatg gtcagacgac
    11221 gctcaaagag ttagcgcgcg agctcgacgt gcccgtgcag gacttgctcc aaatctgcgc
    11281 aagtcttgat gagtttgggg cgttagagcg aggccctacc aatgtcctcg attattacgc
    11341 agcccttctg gctactagcc tggcgcgccc gtcgactccc caaagcgctt tacgtaccaa
    11401 gcagcccgag ccgattctgg tgttggggca cggagagttc gcgcagcggg tcctgcaaga
    11461 actgcaagcc tctctcaact cgcctgtctc gctcatcgaa gaggcagagt tattgcaaga
    11521 actaagcgag caggatttga cagaacacga agatggcctg gcaagcatgc aaaccgcagt
    11581 gcgcttcacc aggtggcgtg atcacttcct tgtcgtggcc ctcgatgtca tcgatccgat
    11641 cttgctccgc aacctgaacg tcattgctac cgagcttggc ctgcgctggc tgcatagcgc
    11701 tatcgacggc cctttcctgt taatcgggcc gaccatcatt cctcagcgca ccccttgcta
    11761 tgcctgcttc gagagccgcg ttggcctgaa cctgcgcgag cacgccagct atgttgccta
    11821 caagcaggcc ctcgtcgcgg gcaaggttca gcccggacgc ccggtgctgc tccgcccact
    11881 ctactcgctg gccgcctcgc tgacggctct ggagaccctc aacaatgtac tgaccggctc
    11941 cgccttcacc gctggcaaag tcctctcgct gtatctccca acgatggagt tcgcctttaa
    12001 cgagatcctg cgtttaccca actgccgtat ctgtgtgcca cgcactgagc gctaccagaa
    12061 gccactctat ttcgacaccc gcgcctatat gaatcagatc cagctgcatc tggaggaaca
    12121 tcctcatggc cgccgccaat agtcctgcgg gccagctgcg ccccctgatc atctgccatc
    12181 gtgaggggct gacccacaag gtgaatacct annnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12901 nnnnnnccag attctcaagc gtgacgcccc gcgcaacagc gtgacgatcc gcttctatta
    12961 ccttaccaat gccgatatgc aggcccatgt agtggcggca gtgatctgga acaaccgcgg
    13021 acatgtgcca gcctgcggta tcgggatctc cgctgagctg aatctggagc tggcgatgta
    13081 caaagcatat ctggaagcag ccgccattcc tcatctggct ctgatggcct tcgtggagat
    13141 gaccagcgcc acaaaaggca atggcatcga tcctactgct atctataatc tggataccaa
    13201 tgtgatgtac tacgcctatc ccgagcaccg ccggctgatc gaagagaagt ttacgagcag
    13261 tcaacggatc aaagccagcg aacttcctgc cgaccatcag ggcggagccg aggagggact
    13321 acagagagta ctcaacgagt tcaggagaac aggcaagcgt ctggccttgc ttgatctgag
    13381 cagtccagag attgaggatc tccatttcca tgttttccgc ttctactcac cggatacact
    13441 gggactctgt cttccctcgg ctccccagct cgcccatcgc cgctatcagg cctacggagg
    13501 agcgactcat gaacggcctc atccctatcc ctgaactgga aaccagcctg ctggcagcgc
    13561 tccttctgct acacgccagc ccggtcatgc tggccaatcg tctggccgca ctcctggagc
    13621 cgatcagacg agtctcccca ctctggctgt atgttgtcgt gctagggatg ctcatcggag
    13681 gtgatctggt cctcatctct ccagatctgc accggatcgc ctggccgacg caggcactgg
    13741 cagtaatagt ggggctgctc gggggcgagt tgggcttctg gctcgatcag gttgtgacta
    13801 ccttgttgcg taaggcgagc agggacacgt ctcgacctct tcggcgcctt cctcccattc
    13861 tcgggccctc ccccagctgg ggggctgtat tgtccctgaa cccactgcaa gcagcagatg
    13921 caacggggag cacagtgacg cggaccttgc taacgcgagg cgagtttctg cccccattgg
    13981 ttgtggctgt gggtatcctg gaagagattg cctatcgctg ggccttcccc tggctgctcg
    14041 gctttgtgct tccctggcga gaactgcccg gcctactctg cggattgatg attgccaatc
    14101 tcttttatgg cctcatccac ctctctttcg gtagcaggac catcttcaca agatggctgc
    14161 tgggcctcct cttcgccgct ctggtcctga tgagtggtag tgtgctggcg gccagcatcg
    14221 cccacggcct ctttaactgg ttggctatga aggcgacact tgcggagcgc aggcgcccaa
    14281 tcacctttgt gagaagccac cccggaggat tctaatgtct ccgactcctc tcgccgcact
    14341 gagcgctctc ggctggatcc tggctgcctt gctgctgcag tatgttctct gccgccgact
    14401 catcatggct acagctcggc acctggcaga gcagctgccg ctcagcttcc attacccaac
    14461 ccgggacgtt gctctcaccc tggcggttgc aggcgctggg ttgaccgccc tcggcatcgc
    14521 ctgggcagtc tcctgggcaa atggcgagaa cctgctaagc ctctttaccg agcatttgct
    14581 gccgctgcaa ctgccaattg gcattctgct tggcctggga gaagcttcgg tctccatgct
    14641 actgagctcg ctggccctgg ccgttttccg cccgtggcgc caaaggcaga taggacctga
    14701 tcttatcaac gagctgcgca ccatcgggcg agctggctgg gtccgagcct atcgccaaac
    14761 gctccagatc tggccggcgc ccctcggctg ggcaagtatt gccctggcac tgctgggtga
    14821 agaactgctc tttcgtggcc tggcagttcg tctgctggcc cccgaaggct tccccttcgc
    14881 gctcgtggcc tccacctttc tcttcgtagc tgtgcaagcg caaggcatgc cttcgtggtt
    14941 cagcgcgctg ccagccatgt gcggtgcact cgtgatcggt ccgatcaacg cctggttatt
    15001 catgaccgtt cccaacattc ttcccctgga gatcgctcat ctaacctttt tttgcagtca
    15061 tgattttata atctctccgc tacgctgtag ctagccagag cgggtgacag gaaggagaaa
    15121 aaggagcgac atcatggctg agacccttga aaggcgaaga atgtcaatgg aagtgagcgc
    15181 tgaaccggct gtcactcagt ttcggcagcc agtgattctt ctggatcagg tgaccaagta
    15241 ctacggaaat gttcaggcac tgcgcggggt gagcctgcgc atcgaggcag gtgaatcggt
    15301 ggcgctactc ggcccaaatg gggccggcaa gacgactgcg atttctctga tgctcggtct
    15361 gctgcgccca tcaacggggc atgtgctgct caacggtggc gacccaacaa tccccgcggt
    15421 ccggcgcgct gcgcgcctgg gtgccatgct gcagaacgcc cgcgtgatcg atctggtgcg
    15481 cgtacgcgag ctactcgatg tcttccgcag ctactatgat cacagtcttc caacagatga
    15541 gctacttgag atcgcgcagc tacatgataa gcagcatagc tacacccagc atctttcggg
    15601 tggagagcta caacgtctgc tttttgctct ggccctggcg ggtgacccgc gtatcctctt
    15661 tttagatgag ccaaccgcgg gcatggacgt cgcctcacgg cgtcgcttct tgcagtgcat
    15721 ccgcgagctt catcgcgatg gacgcacgat tatcctgaca acgcataact tggccgaggt
    15781 cgaaggactc tcccagcggg tgatcgtgct caacgaggga cgcatcgtag cagatgactc
    15841 tagcgaggcg attcgcgcga cggcgagcgg gcagttcgtg agctttctgg cagaggaaca
    15901 aaccgatcag ctcctggcag cgatcccggg cgtcctacga atcgagcgtc aggggccacg
    15961 agttgtgctg ctcacccgag acagcgatgc gctgctcaaa gacctgcagc gacaagggat
    16021 tgctacccca cacctggaga tccgcggagc cagccttgag gaggccttct tagcgctgac
    16081 gaggaaggag gaacagacat gaccctgcta gctttgcgtg cccagagcaa gctagagctg
    16141 ctgcgctttc tgcgcaatgt gcgcgcgctc ttttttacgc tgttggtccc gatcggctac
    16201 tatctgattt tctcctatgg cttcggcaat actcatgact tgcagctcca ctttggtatc
    16261 gccatggccg gctttggcac tctcggcgtc tcacttggca ccctgggatc gcgccttgct
    16321 caggagcgcc agcttggctg gctgcgcctg ttacagacaa ccccgctcac gcctctgacc
    16381 tactttgttg ccaaggtgat cgccaccttc agcatggccg gtcttacgat tatcggcgtg
    16441 ctgaccgtag cgctactaga gggattacga gtcgacaact actgggcgct ggtgacctcg
    16501 gccctcattc tatggggcgg ctcactgcct ttcattgcgc ttgcctttgt gatcggctcc
    16561 tggaccgatg ccgagactgg ctacgtggtc agtatcggtg tctatcttgt gctaggttac
    16621 ctgggaggct tgctgcaacc actccagttc atgccgagtg ttctgcaaga cgttgctcgc
    16681 tggcttccct ctacccatta cttcttgctg gcgttgcgcc ccttgcaggc ggcctcctct
    16741 ggctcagctc tcgaagatgt gctgatcctg ctggtttata ccttgctttt cacggccttg
    16801 gccatctgga gctatcgccg cgccggaacg gcagaccggt aggaggcagg agcgactcgc
    16861 ttcctctgac cgctactggc gggcttggtc tttgatccag ccgcgggccc gcgccaggcg
    16921 cagcattttc tctttaccgg aaacgcctag tttttgttgg agattacgca tatgcgtttt
    16981 cacagtgctc ggactgagat aaaggcgctg ccctatctga cggtaggata agccttcagc
    17041 cagaaggttc agcagctccc actcgcgtgc cgagagtgcg gcacgttgct gccagttata
    17101 ctctgcttct tgtaggaggc accgaaggca gcaagcgaac tgagccgggt cagccatgtg
    17161 aggatgcttg agggcttcaa gtgcgctctc cagccgctga cgatgctggt ccagcttgac
    17221 gccgtaagca gcaaaggcgg tctccagagc cgccagtagc acggggacct gtacgcccgg
    17281 tagtgtatcg tggatcagag gagacccact agctaacgtc acattcggac cacagtacgg
    17341 tgacagagag agggagctct gcagagaagc actctctctg ttctcagtgg cttcaggcct
    17401 cagcgattcg ctcaactgaa acgcgggaga gcctagctgg agaggcgagt tactctggtt
    17461 gctgaagatg aaggccagga gatgccgacg gcgcctcagc aggagatgca accccgccgt
    17521 gagactgata accaagaacc agagtagcat cgagagccaa ctggcgggag gctgattggt
    17581 cgagagccgg aggagcgcta tgattagctc gctccagcag aaagtgagca gcacgatcag
    17641 cgcgcctacc actccatacg cgattgccca tccataggct ggcaggagga aggctgcggc
    17701 ggcaagactc gatggcaggg gggcaaagag caggttgaca gcgacgcaga gagcaagatc
    17761 aatggccaaa gccagaggcc acaggcggcg ggcctgtgtc ctccagtagc agactaccag
    17821 aaaggtgaga aaagcccaca agcagaaggt gatccccaga gcgatggccc agaaggcaag
    17881 gggagaaggg gtgacttgca atgagagcag ggtacctatt cccgcaattg ctcgcaggag
    17941 cgtaagcatg tagcagtgtc tgagctgcag gcaagactca gaagtggtca tcgtgttctg
    18001 gccagacatc ttttcccccc gggatgaagg agttagaaag ccagtgagca gagagtacgg
    18061 cccaagtgtc ctggcgtgga agtggagcat agtgatgaag cctgccacct ccgcttcctc
    18121 tgctgctttg gtgctcagat gggaggcgtg ctcgggcaga gaagattacc gagccagcca
    18181 gcctgacagg ctcagtcccc gaccttgtcc gaactgacga aatacctgtt tgagatctga
    18241 atgagaccgc ttcttgatcc aatcatatgt ccacgggacc ctctgctgag gagtcttctc
    18301 ccccaaagtg gtcttatgct ctacccccat tccgattctg attctgaaca aatgaggggc
    18361 tagggatgac actaatagta tagtgaatgg aagacagttt ttccaggcaa tcttctccta
    18421 atgcaaggcc tgacctcgca ttccctaatg accaggtttg acctcagaca acaggtaaag
    18481 aaaaagggtc caccagaaaa gccagaggca tggagacaat agatcaagaa gctccctccc
    18541 ccaatcggta ggcagcggca ctcttctgga cctcggcgag gatgcaggct ttcccgccga
    18601 ggcacctgca cttcctcgta tcaacccact gcctccaggg cttccaccag ctccaccagc
    18661 cggcctgtgg gcgtgagctg ctctcaccac cgacgcggga ttccaggcac actcgcggtg
    18721 gcgaggagcc gctcatacgg cgcagctggc gtctccccct gccagccatc cgtagccacg
    18781 acctcgactc gcgcgccata gcccgccgcc tgcagccggg tccgcgcctg ctctgccagc
    18841 tcttcctcca cctcgaccgt ccagacctgc cccgttggcc ccaccagttc tgcgagcagc
    18901 gcggcattgg agccggtgcc tgtcccgatc tccagcaccc gctggcccgg ctgcacttcc
    18961 agcaggcgcg ccatcgcggt cggcgcgctg gaggaactga ccggcagacc ctcccgcagc
    19021 cgggtcacca gaggcacatc gcgctagatc gcctcgaccc acgctgccca ctgctcctgg
    19081 gcctcctggc cctggccctg gcccgcctcg cagcgctgcc agcgcctcgg atggccagcg
    19141 gaagggaccg gtgtgtcaaa ggtcatcatg ccacctccag gctggggaca ggaaccggtc
    19201 tgtcaaagct catcatgcca cctcctctgg atgggcaagc agcctggcca tcgcttccgc
    19261 ctcctcttcc cgatttagag ccagggtggc gggttcacga cgatacgatc cagccgaatc
    19321 cggcaggact gccattcctc ctccgacagg gtcaccacct gatccgcttg caagacccat
    19381 tgccccccgg gctgctgcag acagagcacg acctctacct tgccggggat cgcccgccac
    19441 agcagcgcct ggccatgcgg cgtctcgatc acaaagggct tgcggttgag tggctggcca
    19501 ggttccctgc tgaccacccg tgccagccgc gctcgggcaa tctcaaagtc ccggtaggga
    19561 ctctcgtgct cccagggagc cagaaacggg cggtagggcg tcggatcaag cgcctcttct
    19621 tcgctcagca gctcgtctcc agcgacctcg cgaaactgca gcgcataccg ctcagccatt
    19681 gggggtcctc ccaggccagg aggcgatgga atgctgtcct gtccccaggc agtcactcct
    19741 catcctcatc ctcctcgtct ggggacggtc gctcttcccc ttcatcgtcc ccgcctggct
    19801 ctggaggcgg gtccgggaca tcgaaatagc ccgctgccgg agcatcatag tcatcgtcac
    19861 ccttcccgcg tgtgagctgc accaccgatc cgatctcgac cagcaacggg tctcccgcca
    19921 atgctgctgc ttcccccttc ggctcatggg ggggaaaggg agccggctgc aaccacggaa
    19981 atctcatcag atcctccttt cgagcagtca tgtgagcttt attccatcca ctggatgagc
    20041 tggtcagcac cgctcgctcc agtctgcctg cccgtcttgc ctcgcccgtt tcccagcagc
    20101 cccacagggg ctgctggcag cctggccact gcttctggcc ctcctcctgc ggctcctccc
    20161 tggcgtaccc agagcgcgag cgccaggcta ctcagcacga tcggttgggt caccgtcagg
    20221 aacggaagtc ggtccagctg gactcgcagg cactcacgat ccagataggg gtccagttct
    20281 cctggccctg cacgcaactc atcttgcagc catcctcgcc gctcccacag cgcgcgaaag
    20341 atggcccgag cgattcgccc tttggtcgct cgcacgcgga ctggctcggg caggtgccca
    20401 cgcatggcct cccggagcag tcccttggga ggctgcccgt ggggagcaat cagcgtcaac
    20461 gggatcgcga gcacctgctc aatcactcgc gggtcggtat agggatcggt gctcgtgagc
    20521 ccggcctcca ccagcggacg ggctgccgct aacgcggcgg tctcggcaaa tcggtcgatc
    20581 cagcgcagcc attcccacac ctggacaggc ccccgctgtc ggcagcgctg acgctccgct
    20641 tcctcgacgg ccagcacgcg ctgccacacc tctggtcgca gccagggagc caggggacgt
    20701 cgatgccagg gagcctccgt ggatcgccag agcggagagc cacgggtcag caggatctgg
    20761 ccccatgaca ttccctgccg atgccagagc cacagagtct gccacacgat ccccaaggcg
    20821 tgctcttgcc agcattcccg cagcatggtc ctccacgccg ggtcccagag cgcatcccca
    20881 aaggtcccac gcaggtacat ccgaacccgc cggctccgcg cgagctggcc cagacaccga
    20941 taccagctgc cgaaaaagag cacagccgtc aagggcaccg gggccagccg ggcaaactga
    21001 ctggcttcct gcaggagagg cgcctcgtct ctaccagctt cctggccggg agagccagtc
    21061 tcaccctgtc atagcctggc actggcagga ccggcatagg accagccagt cagacaagcg
    21121 caagcagtca gggagtggcg ggccgctcag acgggccagt actcttgccc tagcaatggc
    21181 cccctgtgct tgcattcccc caaagcggcg cctataatag gtctgtcttt cgacgaggag
    21241 accagaagag gccggtctgg agctggcccg cctgccagcg aagccagccc cctgggggaa
    21301 cctcgtgcac tgttcgccag ggcgaggcgc tgcgaaagtg cccggttgcc agataccagc
    21361 agacccagtc cgcatccaga tcacaggggc cattggtggc ttgcaagagc caggcgggat
    21421 cagaggccag gataagcgtc tgcccccaga cctgatagaa gagagggcgc aacccaaacg
    21481 ggctgcgtgc tgccagcccg agccggcgtt cttcatccca ccacacacag gcataatccc
    21541 cttcgagccg gcgaaggttc tcctctcccc agcagcggta actccacgcc aggtattcca
    21601 gatccgacag tctcgcagga actgcatggt ggacccgaag tgcctccagc agggcactcc
    21661 gataatagag acgaccgtcg gccgcgaccc agagcgagcg acaggacccc caggatcgcg
    21721 ggcaggcttc gtgctcaaga gcttgccaac accagcagcc atgactccgc cacgagaaga
    21781 gctggtctcc acgctggcgc accagggccc caatctgcag ccagcgggtg gcgtcaatgg
    21841 gggtctctgc ctccggagga tccgggtcca gagacgccca gagacagaag ccactcatcg
    21901 gagctcctcc ttcctcgact gcagcaggtc tcgtccacta tgaaagatgg gctgcagtcc
    21961 agcaagcatt gccctgtggg ccagccaccc aagccctgcc ttccagaaga gggggccatc
    22021 aggtccttcc acccaggcat gggccgtaaa gggagccgtc gagaccccca gcacgacgtg
    22081 cgcactcatc ccccgcttgc gaaggagcca ccagagcgca agactttgct ccaggcacgt
    22141 gggtggcgcc tctgcaccag gctgacccgt cgcacccagc gacacaggtc cctgaccagc
    22201 ggacgcgcgg ccctccccat ctggtccgaa gctgttcctt gcagcgtctg tcccacggcg
    22261 atgacgagga gcaatccatc cgcccggcgg agcagccatc gaatcccccc cagggtgagc
    22321 caggcatcga gtggctccca gcatgaagga cagcaccgca acacccagag caggaaagag
    22381 gagatccctc gcctgggacg aggcagctcc gggtcatgca gcgccaggcg gaccatctct
    22441 tgctcaaacc gacagaccgc ttccttcgcc tcttcctctc cgatcccttg ctgctgtaac
    22501 acagagacca gctcctggcc tcgtttgccc acctggagcg cttcccagag ggaccagccg
    22561 cggggagtga ggccaagata gcgtccgcgg cacaagtcta acaggactcc cccctcagct
    22621 gtgggggtag caaagatcag cgggagaggg acagctgccc gctgccccgg gctggccaca
    22681 cctgtctgtt ctgcctgtct cctcacttca gcagcacaca cggcagttct tgcctccttc
    22741 ctggcctttc cctgctcaac tcgctccttg cccgacgccc tcacggcgtg gggccgggct
    22801 tgccccgcct ggggccctcc agcagcgcac gcagccgcgc cacctcgggt gcgtccccaa
    22861 atggggaagc gctcagccgc tccgtgagct gctgcaatct cgccagattc acctgactct
    22921 cgatctgacg cagcggctcg accagatcca gcgctagagc cgtccccatc tcatcgtctc
    22981 ccagctcgat agaggcccac gccgccttct ccagtataga agaagatctg taaccctgca
    23041 agtgcagcag cggaaggtgt tcttccactc tgttccgaaa ggaggatcac gctctgctgc
    23101 tcccttgagg tcgctcgggc ggagtgggaa gagcagatca ccagcagctg ggtgcaagcg
    23161 atggagtcac caggcagcca ggacaggcgg agcacagaaa gggcagaaac ttataccaga
    23221 agctttacag aaaggtcatg ttcctctccc tccgatcttc ctttgtagaa cggggagcaa
    23281 cgatctccac tggaaacagc gccagctcgc aaggaagctg ccccccaggg gttcagcgat
    23341 cgaccaggag cgagagcaag aggaaggggg agcagtatct catggcaact gctatccaac
    23401 ctctgtcgcc tgttgagagg caacggcctg cggccctcac cagcgctgca agggctgagg
    23461 cctccagcgc tgacgtccgc tcttttcccg ttcccgtcac gctcccagcc ccgaggccag
    23521 gggagacacg ggcttctcag aggaggtgag ggatgccctg gtggtggcac acgcgccgct
    23581 cggcttccga tcggcgcgcc ggcgcttcga agacatgccc ttttttcttc ccaaagacca
    23641 gcaggagctg aaccggctcg actctcagca cgctgtgctc cgccaggtct tccgcgacag
    23701 cgtgctcgcc cccgtgcagg acctgctgca cgagggcacc gtcgtcctgg acgtgggcat
    23761 cagccccagt cgctgggcct tcgagagaga agcccccggc gagacctccc tcccttcttg
    23821 cctctcatgc gcgactgctg tatcctcttg agtcagaaga gctacatatt ggcatctcgc
    23881 tgtcatgcct gccacaccat gacagaataa gcaagcggag aattgaggtg tgtgatggag
    23941 agcacgtcct gcgagcggga aacgagcccc ctctttcgcg tctggctctg tnnnnnnnnn
    24001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    27001 nnnnnnnnnn nnnnnnnnnt tcctccctcc ctccactctc ccatcgatcg cacaggattc
    27061 tcccccgatt cgcacgttcc tggtggtagg cttatggagg agtgaacgag cacaagttac
    27121 ccgcggcgat cggagccacc gagatcccac cgagtgagca aggcctaatc ccgaggccaa
    27181 gaagcgacac cacagagaga aaggagagcg agccaatggc gaccttcccg caaccgctga
    27241 tccacctggc gatgaggctg cctccctgcc ctcactgcag ccggcggcag gcacagcccg
    27301 aggtggcttc cctgcccacg caggcatcgg ccacctccct cgttcctggc cgcagggggg
    27361 gcgcctctgc cgagctatcc tctcctcctg atgagaagac gtccattgct ctacgaaggg
    27421 agtactgata tggccttctg gcgtcatctt ttccgcaggc gccgccgagt ccaggcggcc
    27481 tccgctgccc ccgccgtggt catgacggca gcggcggtga gcacagcccc cgagtacggg
    27541 cattcttcgc ccttcgccca gcgccgctat ctggaggacg tgccctctct cttccccaaa
    27601 gatcccctgg aagatcagcg gctcaattac cagcaccacg ccttgtatcg caccctgagc
    27661 aaccattacc tggccccgct cgctcctgag cgcacccgca ccatcctgga cgtgggcacc
    27721 ggcatctggg ccttccagag gcaggccctc tttccccatg ctctctgctc gactgcttca
    27781 ccggcatcag ccgccagctc ggcttcgagc tggccgtcct gcgccggttg ggccaggtcc
    27841 tgccgccagc aagcagatgg accacctcgg tcacgctcac cacgaggccc ctcgctcctg
    27901 tgagcacccg ctcctcgcct tccagctggc cgacggcgaa tctccgtcag acaggctggc
    27961 aggaagtgcc tggggccggg gccactgcct gtcaacgtgc cgagggcgcc aggagccgct
    28021 gtggtccagc gagggcgggg cgagccagcc agagccctgc ctctgtctcc tccacgccag
    28081 gccccttcct gcttcctcct cctgtgcggt tccctccttt ccgcccggtc ctcctttcct
    28141 tctactctgc gaagcgctgc gccttctccc gaaaccgcca tcgatgcagc ggaagctcct
    28201 cagggaggga caatccagct cgtgctcgca gcacctatcc cccctccgca ggaggcatcg
    28261 agacggcttc ctggagctcc tcgccttcct gtctcagact gtggtaagct agaagtgttt
    28321 cagcaagaca agagaaaggc ggaatctctc tatggcggaa tctctctctc tgtcagcaaa
    28381 ggaggtgctt gctctcccca atcaggcact cctggtttcc ttcgctcgtc tggcggaaga
    28441 gttgctctcg cctctcgggg cgcgttggct tcacgtgcag ggggtcgccc gtgttgccct
    28501 gcgtatcagt cctctcttcg ctccagatga tgcctggcat ctgatcgcgg cggcctatct
    28561 gcatgacgtg ggctacgctc ccgctctctg gcacacaggt ttccatcccg tggatggtgc
    28621 gctgttcctt cgccagcagg gatatgagcg gctggcatgc ctggtggccc atcattcgga
    28681 ggcccgcttt gaagcccatc tgcgggggct ggaggatctc ctctcgcgct ttccgcgtga
    28741 gcgatcggtg gtggctgatg cactgacctt ctgcgatctg acgaccagcc ctcttggcac
    28801 acgggtctcc ctccaggagc gcgccagaga ggtcaccctg cgctacggtc cagatcacct
    28861 cgtcacgcag gccctccgac aggcgctccc caccaaggcg ctggccatcg ctagaacccg
    28921 gcgctggttg caacgccacg gcttggaccc agatcacctt accgaatgaa gggatgtcca
    28981 caatagtgtt ggtaatcttt gatccggagc aaactggaac gatgcatggg gagacggtcc
    29041 agttcactca cagagaagaa gcgcaggtca cgcgactctg agctgatttg aagactgccg
    29101 ccgatgactc tgcaggcaaa acacagtgag aattgctgcc gaacttctcc gtggtctaaa
    29161 gcaatcacat gccggggatc tgaatagatc cccacaagat attcaggcag cacgtcgagg
    29221 cctgtttctt ccttgacttc tcgtagaagc gtctgggtaa tgctttcccc tagctccata
    29281 gctcccccgg gtagagacca gaggccatct tcctggcgtt gctgcaagag aatccgtccc
    29341 tcctcgtctt caatgatcgc ccacgcggca ggaacgatcg cgtttgcttt gggagcggca
    29401 ggatcatcat aataatcaat acgcattgtg cctcctcctt tacgccgagt ggcatccctc
    29461 tattgcttct agaggagtag ttgtctccca caccgcttca aagtgtgcgg caaagttcgc
    29521 aaagatacct cctgggataa gcgaacgaag atgaagcaga ggagccttcg atccgtgcag
    29581 gcggaaaagt tgcggcataa caaacatttc gtcgtcgaat ctagcgtaag aaatatagag
    29641 gacagtacta tgaaaacgta tctgaatgcc atcatggtgt aaaatatctc gaaagtgata
    29701 cagggtcgtc tgaatccttg gaggaagcgt cccgggatac tcctctccat ctcgcatccg
    29761 cagagccact gaatcaggat gcgcgagcgc gattctcacc tggcaaccag ttgacgcttt
    29821 ctccttgagc agctcgacaa ggtaaggatg ctgctcaggg agaaacaaga gagcaattcc
    29881 caggagatca atgtgcttct cggccttgac gaagagacgc caccaggctt cgggaggaac
    29941 gtcagagcga tgggcatatg cggcgagcat ttctgcagtg cagtcagagg acgatgaagc
    30001 gttccccttg agtggccaga gcgatttttc aggtaattgg agcaattcag agactttcca
    30061 ccgatgtcgt ggatgaggga gacacccatg taaccaacgt ctcaccgtct ttggatcgac
    30121 attcacccgc tctgctagcg tttcaacatc aagatgtgca gactccattg cgctccgcag
    30181 tcgctcattt tccatgacta tatcaccctt tcaccaatca tctggaagga cacaacggac
    30241 atttctagcc tatcacaaaa tgtccagata tgtccattcc tgaggttcct aagtccctgt
    30301 cttcgagcta gcctatagct aggcagacgg caggaggatc actgggaagc gaccgtttct
    30361 cagaaactga ttaccggcga tggtatgcct cctcttgttc ctgatgctga gatgcaaaga
    30421 cctggaaaag agggcaatcc catgaccacc ctgcagcaac cgctgccttg cccgtccgca
    30481 gaccgacagc tctctgtccg cgctgccgtc gtctaagaag atgcatccag atcgtggaaa
    30541 ggagcattga catggccttc tggcgtcatc tcttcccgcg ccgccgcgcc cgtgcgcgct
    30601 ccgtctcttc tcccgccgtg cccaccgtgg tcacgtcgac agcggcggtg agcacagccc
    30661 ccgagcacgg gcattcttcg cccttcgccc agcgccgcta tctggacgac gtcccgtatc
    30721 tgctgcccaa ggacccactg gaagatcagc ggctcaacta tcagcatcat gcgctctatc
    30781 ggaccctcag caaccactac ctcgcgcccc tcacccccga gtcaatccgt accatcctgg
    30841 acgtaggcac cggcaccggc atctgggcct tcgagatgca ggccctcttc cctcacgccc
    30901 tcgtggtggg cgtcgacgtc tccttgcaat ccctgcccca gccggtgccc cccacctgcg
    30961 tctttgtccg ggcgaacgtg ttggagggct tgccctttcc cgacggccaa ttttgttata
    31021 cccatcagcg gttgctggtg gccgccattc ccgcccaggc ctggcccggc gtcgtccgcn
    31081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    32041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    32101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    32161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    32221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    32281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    32341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    32401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    32461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    32521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    32581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    32641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    32701 nnnnnnnnnn nnnnnnnnnn n
//
