GCF_003264145.1 - 3 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_NAQX01000009.1 (Dolosigranulum pigrum)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1.1	RiPP-like	83,002	95,155

NZ_NAQX01000071.1 (Dolosigranulum pigrum)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 6.1	terpene-precursor	46,617	67,507

NZ_NAQX01000046.1 (Dolosigranulum pigrum)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 19.1	lanthipeptide-class-ii	41,076	63,532

Region	Type	From	To	Most similar known cluster
Region 1.1	RiPP-like	83,002	95,155
Region 6.1	terpene-precursor	46,617	67,507
Region 19.1	lanthipeptide-class-ii	41,076	63,532

No secondary metabolite regions were found in these records:: NZ_NAQX01000064.1 (Dolosigranulum pigrum); NZ_NAQX01000068.1 (Dolosigranulum pigrum); NZ_NAQX01000069.1 (Dolosigranulum pigrum); NZ_NAQX01000070.1 (Dolosigranulum pigrum); NZ_NAQX01000011.1 (Dolosigranulum pigrum); NZ_NAQX01000012.1 (Dolosigranulum pigrum); NZ_NAQX01000015.1 (Dolosigranulum pigrum); NZ_NAQX01000019.1 (Dolosigranulum pigrum); NZ_NAQX01000022.1 (Dolosigranulum pigrum); NZ_NAQX01000001.1 (Dolosigranulum pigrum); NZ_NAQX01000027.1 (Dolosigranulum pigrum); NZ_NAQX01000028.1 (Dolosigranulum pigrum); NZ_NAQX01000002.1 (Dolosigranulum pigrum); NZ_NAQX01000003.1 (Dolosigranulum pigrum); NZ_NAQX01000004.1 (Dolosigranulum pigrum); NZ_NAQX01000005.1 (Dolosigranulum pigrum); NZ_NAQX01000006.1 (Dolosigranulum pigrum); NZ_NAQX01000007.1 (Dolosigranulum pigrum); NZ_NAQX01000055.1 (Dolosigranulum pigrum); NZ_NAQX01000056.1 (Dolosigranulum pigrum); NZ_NAQX01000058.1 (Dolosigranulum pigrum); NZ_NAQX01000008.1 (Dolosigranulum pigrum)

Compact view

NZ_NAQX01000009.1 - Region 1 - RiPP-like

Download region GenBank file

Download region SVG

Location: 83,002 - 95,155 nt. (total: 12,154 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

B8A46_RS05200: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: acetyltransferase

B8A46_RS05205: Chloramphenicol acetyltransferase

smcogs: SMCOG1156: Chloramphenicol acetyltransferase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000558.5	0.49	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002579.2	0.45	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0001862.4	0.45	ribosomal	pallidocin	Aeribacillus pallidus
BGC0000617.5	0.44	ribosomal	coagulin	Bacillus coagulans
BGC0000504.5	0.43	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0002306.2	0.43	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0002700.2	0.41	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0001407.5	0.41	ribosomal	bicereucin	Bacillus cereus SJ1
BGC0000619.3	0.41	ribosomal	gassericin T	Lactobacillus gasseri
BGC0001388.3	0.41	ribosomal	gassericin E	Lactobacillus gasseri

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000558.5	0.49	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002579.2	0.45	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0001862.4	0.45	ribosomal	pallidocin	Aeribacillus pallidus
BGC0000617.5	0.44	ribosomal	coagulin	Bacillus coagulans
BGC0000504.5	0.43	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0002306.2	0.43	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0002700.2	0.41	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0001407.5	0.41	ribosomal	bicereucin	Bacillus cereus SJ1
BGC0000619.3	0.41	ribosomal	gassericin T	Lactobacillus gasseri
BGC0001388.3	0.41	ribosomal	gassericin E	Lactobacillus gasseri

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

NZ_NAQX01000071.1 - Region 1 - terpene-precursor

Download region GenBank file

Download region SVG

Location: 46,617 - 67,507 nt. (total: 20,891 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

B8A46_RS08890: 3-hydroxyisobutyrate dehydrogenase

smcogs: SMCOG1100: 3-hydroxyisobutyrate dehydrogenase

Hydrolases: peptidase

B8A46_RS08845: methionine aminopeptidase

smcogs: SMCOG1172: methionine aminopeptidase

Ligases: synthetase

B8A46_RS08875: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.38	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0000639.3	0.38	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.37	terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0001456.3	0.36	terpene	isorenieratene	Streptomyces argillaceus
BGC0001605.3	0.35	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0000665.5	0.35	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0000527.5	0.34	ribosomal	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0000633.3	0.34	terpene	carotenoid	Streptomyces avermitilis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.38	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0000639.3	0.38	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.37	terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0001456.3	0.36	terpene	isorenieratene	Streptomyces argillaceus
BGC0001605.3	0.35	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0000665.5	0.35	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0000527.5	0.34	ribosomal	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0000633.3	0.34	terpene	carotenoid	Streptomyces avermitilis

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor		FPP	C15	acyclic	PP

Genes with terpene domains:

B8A46_RS08875: PT_FPPS_like

Domain 1 (29 - 275): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:: IPP, DMAPP → FPP

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (3):

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 19.12 out of 30.11

Confidence: weak

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 20.23 out of 30.11

Confidence: weak

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 20.81 out of 30.11

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description

NZ_NAQX01000046.1 - Region 1 - lanthipeptide-class-ii

Download region GenBank file

Download region SVG

Location: 41,076 - 63,532 nt. (total: 22,457 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: glucosidase hydrolase

B8A46_RS06260: Alpha-glucosidase

smcogs: SMCOG1257: Alpha-glucosidase

B8A46_RS06330: alpha/beta hydrolase domain-containing protein

smcogs: SMCOG1066: alpha/beta hydrolase domain-containing protein

Lyases: cyclase

B8A46_RS06305: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000504.5	0.58	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000554.4	0.52	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000539.5	0.52	ribosomal	nukacin ISK-1	Staphylococcus warneri
BGC0002005.2	0.52	ribosomal	RaxX	Xanthomonas oryzae pv. oryzae
BGC0000525.5	0.51	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000500.5	0.50	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000626.3	0.49	ribosomal	thuricin	Bacillus thuringiensis
BGC0000558.5	0.49	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0001210.5	0.48	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0001407.5	0.48	ribosomal	bicereucin	Bacillus cereus SJ1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000504.5	0.58	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000554.4	0.52	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000539.5	0.52	ribosomal	nukacin ISK-1	Staphylococcus warneri
BGC0002005.2	0.52	ribosomal	RaxX	Xanthomonas oryzae pv. oryzae
BGC0000525.5	0.51	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000500.5	0.50	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000626.3	0.49	ribosomal	thuricin	Bacillus thuringiensis
BGC0000558.5	0.49	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0001210.5	0.48	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0001407.5	0.48	ribosomal	bicereucin	Bacillus cereus SJ1

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for B8A46_RS06305

B8A46_RS06295

Leader:

MKNKVNNWKTPVYEKEEDYDNPAGDIFRELKSDDIDKVMASG

Core:

TANTYCRCYSGRHSCGRACTITAECPVFTVACC

Core with dehydrations:

DhbANDhbYCysRCysYDhaGRHDhaCysGRACysDhbIDhbAECysPVFDhbVACysCys

antiSMASH-DB 4.0 matches for B8A46_RS06295

100.0%

NZ_CP040409.1and 4 others:

NZ_CP040411.1 Lanthipeptides: FE334_RS06825_lanthipeptideNZ_CP040422.1 Lanthipeptides: FE323_RS09430_lanthipeptideNZ_JH601103.1 Lanthipeptides: HMPREF9703_RS02710_lanthipeptideNZ_NAQX01000046.1 Lanthipeptides: B8A46_RS06295_lanthipeptide

Lanthipeptides: FE336_RS08590_lanthipeptide

TANTYCRCYSGRHSCGRACTITAECPVFTVACC

73.5%

NZ_JADNMH010000005.1:

Lanthipeptides: I2E99_RS07105_lanthipeptide

TANTYCRCYSGRHSCGRACTITAECPVFTVACC

TANTYC CYSG+ SCGR CTIT ECP+ TV CC

TANTYCHCYSGKDSCGRRCTITTECPIATVVCC

73.5%

NZ_JADPCZ010000011.1and 1 other:

NZ_OW659477.1 Lanthipeptides: NMG62_RS06660_lanthipeptide

Lanthipeptides: I4W03_RS06785_lanthipeptide

TANTYCRCYSGRHSCGRACTITAECPVFTVACC

TANTYC CYSG+HSCGRACT+T ECP+ T+ CC

TANTYCHCYSGKHSCGRACTVTTECPIATIICC

with 79 more sequence matches

Only the first 10 are displayed here.

69.7%

NC_011900.1and 2 others:

NZ_NCVD01000002.1 Lanthipeptides: B7702_RS00350_lanthipeptideNZ_NCVL01000015.1 Lanthipeptides: B7694_RS04515_lanthipeptide

Lanthipeptides: SPN23F_RS06435_lanthipeptide

TANTYCRCYSGRHSCGRACTITAECPVFTVACC

TA +YC CYSG HSCGR CTIT ECP T CC

TARSYCACYSGEHSCGRGCTITTECPFLTFICC

69.7%

NZ_CP102135.1:

Lanthipeptides: NQZ98_RS01500_lanthipeptide

TANTYCRCYSGRHSCGRACTITAECPVFTVACC

TA +YC CYSG HSCGR CTIT ECP T CC

TARSYCGCYSGEHSCGRGCTITTECPFLTFICC

69.7%

NZ_FQTY01000002.1:

Lanthipeptides: BUB33_RS04605_lanthipeptide

TANTYCRCYSGRHSCGRACTITAECPVFTVACC

TAN+YC CYS + SCG CTIT ECPV TV CC

TANSYCHCYSNKDSCGHGCTITTECPVATVICC

67.6%

NZ_LR595858.1:

Lanthipeptides: FQT45_RS03330_lanthipeptide

TANTYCRCYSGRHSCGRACTITAECPVFTVACC

TAN+YC CYSG+ SCGR CTIT ECP+ T+ CC

TANSYCHCYSGKDSCGRGCTITTECPIATIICC

66.7%

NZ_JVCZ01000028.1:

Lanthipeptides: ADG88_RS11420_lanthipeptide

TANTYCRCYSGRHSCGRACTITAECPVFTVACC

TA +YC CYSG +SCGR CTIT ECP T CC

TARSYCACYSGENSCGRGCTITTECPFLTFICC

64.7%

NZ_GG666304.1:

Lanthipeptides: HMPREF0077_RS09155_lanthipeptide

TANTYCRCYSGRHSCGRACTITAECPVFTVACC

TANT+C CYSG+ SCG CTIT ECP T+ CC

TANTHCHCYSGKDSCGHGCTITTECPFATLICC

64.7%

NZ_JAESIP010000017.1and 3 others:

NZ_LT907978.1 Lanthipeptides: EHLA_RS12685_lanthipeptideNZ_QRYY01000029.1 Lanthipeptides: DWW21_RS18370_lanthipeptideNZ_SPFW01000044.1 Lanthipeptides: FGQ81_RS16590_lanthipeptide

Lanthipeptides: JMK14_RS12260_lanthipeptide

TANTYCRCYSGRHSCGRACTITAECPVFTVACC

TANT+C CYS SCGR CT TAECP+ T+ CC

TANTHCNCYSEDASCGRLCTGTAECPIMTIICC

47.1%

NZ_LMFO01000023.1:

Lanthipeptides: allorf_629531_629758_lanthipeptide

TANTYCRCYSGRHSCGRACTITAECPVFTVAC

+ NTY CYS + SCG CT T ECP + C

SPNTYNSCYSKQKSCGNFCTFTTECPFLSFCC

36.4%

NZ_CP043317.1and 1 other:

NZ_CP043317.1 Lanthipeptides: FYC74_RS17680_lanthipeptide

Lanthipeptides: FYC74_RS17680_lanthipeptide

TANTYCRCYS-GRHSCGRACTITAEC

T NT+ S G H G CT+T EC

TTNTFSLSDSLGNH--GGWCTLTKEC

36.4%

NZ_JAQDBP010000004.1and 18 others:

NZ_JAQDBP010000004.1 Lanthipeptides: PGY07_RS07085_lanthipeptideNZ_JAQEAL010000002.1 Lanthipeptides: PGU65_RS02165_lanthipeptideNZ_JAQESL010000010.1 Lanthipeptides: PG840_RS09145_lanthipeptideNZ_JAQEUC010000007.1 Lanthipeptides: PG788_RS06860_lanthipeptideNZ_QRHW01000005.1 Lanthipeptides: DW641_RS05035_lanthipeptideNZ_QROS01000011.1 Lanthipeptides: DW021_RS13630_lanthipeptideNZ_QRPQ01000001.1 Lanthipeptides: DWZ74_RS02490_lanthipeptideNZ_QRZZ01000003.1 Lanthipeptides: DWV87_RS03165_lanthipeptideNZ_QRZZ01000003.1 Lanthipeptides: DWV87_RS03165_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: DW767_RS16350_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: DW767_RS16350_lanthipeptideNZ_QSKF01000004.1 Lanthipeptides: DW740_RS06305_lanthipeptideNZ_QSKF01000004.1 Lanthipeptides: DW740_RS06305_lanthipeptideNZ_QTZB01000014.1 Lanthipeptides: DXC15_RS13895_lanthipeptideNZ_QUCI01000011.1 Lanthipeptides: DW648_RS10830_lanthipeptideNZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03630_lanthipeptideNZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03630_lanthipeptideNZ_QUKU01000006.1 Lanthipeptides: DXC27_RS05470_lanthipeptide

Lanthipeptides: PGY07_RS07085_lanthipeptide

SCGRACTITAEC-PVFTVACC

S G CTI+ EC +FT+ACC

SSGVVCTISVECGSIFTLACC

MIBiG 4.0 matches for B8A46_RS06295

18.2%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

GRACTITAEC

G CT+T EC

GAYCTLTVEC

18.2%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

GRACTITAEC

G CT+T EC

GGWCTLTKEC

10.3%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTITAEC

CT++ EC

CTLSKEC

B8A46_RS06340

Leader:

MKNRIKEFRKPLGLSQHRLGKKVGVSRVSINKIETGKTIPNLKLASDIADALNTS

Core:

IYKVFDLDGEENYCYCDNQSL

Core with dehydrations:

IYKVFDLDGEENYCysYCysDNQDhaL

antiSMASH-DB 4.0 matches for B8A46_RS06340

100.0%

NZ_NAQX01000046.1:

Lanthipeptides: B8A46_RS06340_lanthipeptide

IYKVFDLDGEENYCYCDNQSL

38.1%

NZ_JADPCZ010000011.1and 1 other:

NZ_OW659477.1 Lanthipeptides: NMG62_RS06680_lanthipeptide

Lanthipeptides: I4W03_RS06765_lanthipeptide

VFDLDGEENY----CYCDN

+FDLDG ++ C C N

IFDLDGTGDFKCPCCGCGN

16.2%

NZ_PIZC01000055.1:

Lanthipeptides: allorf_15720_15893_lanthipeptide

LDGEENYCYCDNQS

++GE YC+ D S

VEGEATYCHRDPDS

allorf_45316_45447

Leader:

MVFFLVVREQIIYC

Core:

VLSKIYNPMTKGGRYCSWDVINCYRAVIE

Core with dehydrations:

VLDhaKIYNPMDhbKGGRYCysDhaWDVINCysYRAVIE

antiSMASH-DB 4.0 matches for allorf_45316_45447

100.0%

NZ_NAQX01000046.1:

Lanthipeptides: allorf_45316_45447_lanthipeptide

VLSKIYNPMTKGGRYCSWDVINCYRAVIE

17.2%

NZ_CP059572.1:

Lanthipeptides: AGRA3207_RS17530_lanthipeptide

GGRYCSW

GG +CSW

GGSFCSW

15.8%

NZ_RYYV01000002.1:

Lanthipeptides: EKH80_RS03455_lanthipeptide

PMTKGGRYCSWDVINCYRAV

P+ GG+Y D++N ++

PLFIGGKYAKADIVNSAESI

with 1 more sequence matches

13.3%

NZ_LIPB01000002.1and 2 others:

NZ_LIPB01000002.1 Lanthipeptides: allorf_1142638_1142808_lanthipeptideNZ_LIPB01000002.1 Lanthipeptides: allorf_1142638_1142808_lanthipeptide

Lanthipeptides: allorf_1142638_1142808_lanthipeptide

PMTKGGRYCSWDVINC

P T GG + W +++C

PATGGGGFRKWLLLDC

MIBiG 4.0 matches for allorf_45316_45447

13.8%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

CSWDVINC

C+W I+C

CAWYNISC

allorf_46890_46967

Leader:

MRVAMTGS

Core:

FSYRHICCGVFLINKIM

Core with dehydrations:

FDhaYRHICysCysGVFLINKIM

antiSMASH-DB 4.0 matches for allorf_46890_46967

100.0%

NZ_CP040409.1and 6 others:

NZ_CP040411.1 Lanthipeptides: allorf_1471108_1471185_lanthipeptideNZ_CP040412.1 Lanthipeptides: allorf_1893493_1893570_lanthipeptideNZ_CP040422.1 Lanthipeptides: allorf_2032974_2033051_lanthipeptideNZ_CP040939.1 Lanthipeptides: allorf_0436749_0436826_lanthipeptideNZ_JH601103.1 Lanthipeptides: allorf_0572098_0572175_lanthipeptideNZ_NAQX01000046.1 Lanthipeptides: allorf_46890_46967_lanthipeptide

Lanthipeptides: allorf_1865049_1865126_lanthipeptide

FSYRHICCGVFLINKIM

11.9%

NZ_JAGPXN010000019.1:

Lanthipeptides: allorf_013625_013804_lanthipeptide

SYRHICCGVFL

+ R++CCG+ L

ARRYLCCGLRL

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

Binding sites found:

DasR

Description: N-acetylglucosamine dependent repressor
Species: Streptomyces coelicolor
Score: 24.72 out of 27.04

Confidence: strong

CatR

Description: H2O2-responsive repressor
Species: Streptomyces coelicolor
Score: 21.97 out of 25.31

Confidence: strong

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.58 out of 21.84

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.73 out of 28.19

Confidence: medium

Additional weak hits (3):

DmdR1

Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 23.09 out of 36.53

Confidence: weak

GnfM

Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 21.17 out of 27.55

Confidence: weak

NuR

Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 21.97 out of 30.98

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

B8A46_RS06295 - Class II

Cleavage pHMM score: -5.60

RODEO score: 0

Monoisotopic mass: 3420.5 Da

Molecular weight: 3422.9 Da

Number of bridges: 7

B8A46_RS06340 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 2512.1 Da

Molecular weight: 2513.7 Da

Number of bridges: 1

allorf_45316_45447 - Class II

Cleavage pHMM score: -6.90

RODEO score: 0

Monoisotopic mass: 3323.7 Da

Molecular weight: 3325.9 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 3343.9 Da N = 1

allorf_46890_46967 - Class II

Cleavage pHMM score: -5.70

RODEO score: 0

Monoisotopic mass: 2025.0 Da

Molecular weight: 2026.5 Da

Number of bridges: 1

TFBS definitions

Regulator	Description
CatR	H2O2-responsive repressor
DasR	N-acetylglucosamine dependent repressor
MexT	Global virulence regulator
ZuR variant 1	Zinc-responsive repressor