LOCUS       NZ_CP031264            24994 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Peterkaempfera bronchialis strain DSM 106435 chromosome, complete
            genome.
ACCESSION   NZ_CP031264
VERSION     NZ_CP031264.1
KEYWORDS    RefSeq.
SOURCE      Peterkaempfera bronchialis
  ORGANISM  Peterkaempfera bronchialis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Peterkaempfera.
REFERENCE   1  (bases 1 to 7090212)
  AUTHORS   Nouioui,I., Klenk,H.P., Igual,J.M., Gulvik,C.A., Lasker,B.A. and
            McQuiston,J.R.
  TITLE     Streptacidiphilus bronchialis sp. nov., a ciprofloxacin-resistant
            bacterium from a human clinical specimen; reclassification of
            Streptomyces griseoplanus as Streptacidiphilus griseoplanus comb.
            nov. and emended description of the genus Streptacidiphilus
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 1047-1056 (2019)
   PUBMED   30741626
REFERENCE   2  (bases 1 to 7090212)
  AUTHORS   Batra,D. and Gulvik,C.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUL-2018) Bacterial Special Pathogens Branch, Centers
            for Disease Control, 1600 Clifton Road, Atlanta, GA 30329, USA
REFERENCE   3  (bases 1 to 7090212)
  AUTHORS   Gulvik,C.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAR-2018) Bacterial Special Pathogens Branch, Centers
            for Disease Control, 1600 Clifton Road, Atlanta, GA 30329, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: HGAP v. 3; Pilon v. 1.22
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 176.4x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003258605.2-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:52:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,114
            CDSs (total)                      :: 6,019
            Genes (coding)                    :: 5,833
            CDSs (with protein)               :: 5,833
            Genes (RNA)                       :: 95
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 186
            CDSs (without protein)            :: 186
            Pseudo Genes (ambiguous residues) :: 0 of 186
            Pseudo Genes (frameshifted)       :: 60 of 186
            Pseudo Genes (incomplete)         :: 147 of 186
            Pseudo Genes (internal stop)      :: 2 of 186
            Pseudo Genes (multiple problems)  :: 22 of 186
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:20:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5090989
            Orig. end                         :: 5115983
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031264.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24994
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="15"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24994
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24994
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14994](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14994)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            583..1521
                     /locus_tag="C7M71_RS22585"
                     /old_locus_tag="C7M71_022585"
     CDS             583..1521
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012738.5"
                     /locus_tag="C7M71_RS22585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022585"
                     /product="ABC transporter permease"
                     /protein_id="WP_111491840.1"
                     /transl_table=11
                     /translation="MRSADRRSPRAARRALPPGLFAAPTLAWLALFFIAPVGLVFWYSL
                     GRKPGLYQTHSNDVLTMGRYHEALSDTFLTSFMGTLRIGLAGTALCLAIGLPFAYWLAV
                     KVRPQRRFVVLALVLVPFWTNFLIRTIGWQVVLSPEGFASRTMQGLGLIDKPFSMLFTP
                     GAVLLGVVYNYLPMMILPLYVALDRIDGSLREASKDLGADRWRTALQITLPLARPGIVA
                     GLLLVFIPLMGDYVTASVLGGARGNMVGQLIASQFQQGQNWALGSAMAIVLILVIALTI
                     LATAVAGIACTWLLTHRRRRELAGIAEGSPA"
     gene            1518..2363
                     /locus_tag="C7M71_RS22590"
                     /old_locus_tag="C7M71_022590"
     CDS             1518..2363
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012738.5"
                     /locus_tag="C7M71_RS22590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022590"
                     /product="ABC transporter permease"
                     /protein_id="WP_111491841.1"
                     /transl_table=11
                     /translation="MSARRTVDRALNAWGLLVIAFLFTPIAVIVAYSFNTGRLLASWEG
                     FGLDAYSSALANDDILSAVSVSVRSAAGAAVIAVVLGTLCGYALARHPGSRVGRLVTVL
                     LALVLVTPEIVSGVALLPWFVSLGVDWNVTVFNSGWVRLVVAHSLFSTAVVTFLVRARA
                     QGMDPSLEEAAADLYTPPLRRFRSITLPLLLPSVLAGGLMAFTLSLDNTIISAFVQVSG
                     STPWPVYVFSAVRAGLRPELAAMSAVMLLLTLAALTAVALVLRRVGGSKDAVNALSGVH
                     "
     gene            2430..4058
                     /locus_tag="C7M71_RS22595"
                     /old_locus_tag="C7M71_022595"
     CDS             2430..4058
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019581.5"
                     /locus_tag="C7M71_RS22595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022595"
                     /product="amidohydrolase"
                     /protein_id="WP_111491842.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.5e-13, bitscore:
                     47.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAANLLIRNAHLPLGDPEAASWSVRVADGRIAEVVPTEVGVPEAP
                     PGTETLDAAGRSVLPAFADSHVHVPESGVELLRCDLTVCESRDEVLRTVADYARSHLGE
                     EWIIGRGWALPHFAEHPPTRQELDAVCGGRPAYLANRDGHSAWVSTAALDRVTPELLRN
                     PPPGGRVDRDADGSPTGLLHESAMQLVSDLVPAVGAEDLRRGLLEAQRRMFSYGVTSWQ
                     DAIVGPFVPTTDIYDVYRRAAADGSLRARVTGALWWPRDASADTLAGLVEQRRGCPPDS
                     RFSCTAIKIMYDGVCETHTAALSRPYVGIAGAGTGLTFFDPADMARAVPQMDAAGFDLH
                     FHAIGDRAVSECLDLVEAAQQANGPRDRRHQLAHLQIADDRSVARMAALGVIANVQPYW
                     AQADPQMLDMTIPYLPGELAALQYRFRTLEDAGVRVAFGSDWPVSTPNPLDWIHVAVNR
                     SHPDEPGAPLFAPEEAMSLRSALRAATAGSAHALRREHEAGTLEPGARADLVVLDRRLD
                     ETVLGEISRTRVDLTLIDGEPVWTR"
     gene            complement(4130..4396)
                     /locus_tag="C7M71_RS22600"
                     /old_locus_tag="C7M71_022600"
     CDS             complement(4130..4396)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888564.1"
                     /locus_tag="C7M71_RS22600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022600"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_111491843.1"
                     /transl_table=11
                     /translation="MNVKETIPGSTELTWYKSSYSGAEGGACVEVAVGWHKSSHSGGAG
                     GQCVEVAACPSTVHVRDSKDKQGPQLAFTPQAWADFVEFAAAQ"
     gene            complement(4393..5214)
                     /locus_tag="C7M71_RS22605"
                     /old_locus_tag="C7M71_022605"
     CDS             complement(4393..5214)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579564.1"
                     /locus_tag="C7M71_RS22605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022605"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_111491844.1"
                     /transl_table=11
                     /translation="MAVNAQDDSGIEILKGFGKQVKLLRERAGLKQAELGKKLGYSEDL
                     VSSVEQGRRVAQPEFIDKADEVLNAGGMLLVLKRSVASARFPEFFRDYVRLEAEAVELY
                     TYDSLVMNGLLQTEGYARAVFATGRPLMDEETIEQRVAARLARQEIFTRRPAPLLGFVI
                     EEVVLRRPIGGKEVLRGQLKRLLEVGQLRNVEIQVMPTDREDHAGMDGPFHLITPKGRQ
                     QVVYMEGQGRSTIVTDVEEVRAIASRYGIIRAQALTPRESLAYIEKSLGEL"
     misc_feature    5400..5413
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.78"
                     /tool="antismash"
     gene            5472..5822
                     /locus_tag="C7M71_RS22610"
                     /old_locus_tag="C7M71_022610"
     CDS             5472..5822
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327663.1"
                     /locus_tag="C7M71_RS22610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022610"
                     /product="ATP-binding protein"
                     /protein_id="WP_407675935.1"
                     /transl_table=11
                     /translation="MTMRRLADWGWPPVGELSTAAALVVAELASNAVLHGRLPGRYFEL
                     RLAVFPDASVLRIEVSDARGERRPEAPTHIPGPEAERGRGLLLVDCLALRWGVLDRLPV
                     GKTVWAELEAAA"
     gene            5819..6193
                     /locus_tag="C7M71_RS22615"
                     /old_locus_tag="C7M71_022615"
     CDS             5819..6193
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C7M71_RS22615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C7M71_022615"
                     /product="hypothetical protein"
                     /protein_id="WP_111491846.1"
                     /transl_table=11
                     /translation="MKADRAAERERVRRLREQGREVVAELRAATGSMGLDFCELHLREG
                     TGPDAEPSIAWGCTTVDTAHRFLDLLALLDATREAEAALMARIFRRYPQLRSGLHPHTQ
                     PSPSPSSPSSSPPSPSRLRY"
     gene            complement(6190..7101)
                     /locus_tag="C7M71_RS22620"
                     /old_locus_tag="C7M71_022620"
     CDS             complement(6190..7101)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491575.1"
                     /locus_tag="C7M71_RS22620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022620"
                     /product="sucrase ferredoxin"
                     /protein_id="WP_114914509.1"
                     /transl_table=11
                     /translation="MDTCTALSRELTEPLAATAATAATWLLLEQPGPWGAKALKESHLD
                     PEVGRALDRAADGTGVRVALIRRPGRHADPPSAGHPRREVVVAHTAPGASWVRRATVAD
                     PAELAALDFAALGAGVHGSFGSDHHGDPLALVCTNGRRDRCCALLGRPLAAELAASGHS
                     EVWEVTHLGGHRFSPTMLVLPYGYAYGRLSAAAAKEVLAGAADGRMVQEGCRGRSCWDR
                     PGQAAELAVRRLIGEERADALTVERQQPSPEGWQVLVRHTGDGRTWDVEVARGVSEPPR
                     PESCGKAPGTPVRMVVRTVAAR"
     gene            complement(7161..8372)
                     /locus_tag="C7M71_RS22625"
                     /old_locus_tag="C7M71_022625"
     CDS             complement(7161..8372)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676082.1"
                     /locus_tag="C7M71_RS22625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022625"
                     /product="phospholipase D-like domain-containing protein"
                     /protein_id="WP_229759204.1"
                     /transl_table=11
                     /translation="MGYIAPAIAVLLGTTLLGVPGTAAAADDTVPLTTTFNNPVGTAAE
                     QDAIRNELISLVNRAPQGSEINGSIYLFTDGGVSSALIAAKQRGVKVKVIVDGDAVTAD
                     GTEYPVLTAGLGTNLSADSWVLACPATRGCIANRNLGDPAINHNKFFLFSQVGSTANVV
                     FQTSANLTTSQRRNFYNNAVTIPDEGSGLYSAYRAYWQDLKTYGSSGSGLATYYKTEQS
                     GPYKTYFFPRQESSGTTYSTDPSTDTIVSLLGNVDCAGGATQIRIGMYAFTRSQVADKM
                     VELKKAGCRVDLIRNAGDGNYGTKVQGILAGKISSITRCDGTATNADGTTRTIGIHDKY
                     MIIEGTYLGGANRKVVFTGSHNYTYPTLRSHDETLLKIDNAAVYDSFKADFEAIRKSPY
                     CTKE"
     misc_feature    8375..8393
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     misc_feature    complement(8400..8416)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.28"
                     /tool="antismash"
     misc_feature    8431..8447
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.13"
                     /tool="antismash"
     misc_feature    complement(8441..8454)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.72"
                     /tool="antismash"
     gene            complement(8488..8610)
                     /locus_tag="C7M71_RS32975"
     CDS             complement(8488..8610)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C7M71_RS32975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_322975188.1"
                     /transl_table=11
                     /translation="MLDAYDQAGCPPPESFRLDIDRDGQHLRHPRLPTLALPRA"
     gene            complement(8872..10017)
                     /locus_tag="C7M71_RS22630"
                     /old_locus_tag="C7M71_022630"
     CDS             complement(8872..10017)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016436871.1"
                     /locus_tag="C7M71_RS22630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022630"
                     /product="hypothetical protein"
                     /protein_id="WP_111491366.1"
                     /transl_table=11
                     /translation="MWKLHDSIAQRFPLVARPRPTCLPLPQRVHALAELADDAGKQGDP
                     GLASTVYNQAALVASDVGVPATARAMCHQHAAAYLHAAPLPSSAAIRALEPLVNLARLQ
                     LRAGQTDDGRQRLLELFDAVTTGSAIRVEGITVPADLVANAADRHDVRSWLWSVLLADG
                     TRALTTAGRWGEALAHIETHRGVGQRMLDGRQVAVLAALTSGNTLEAGSLLAHAVPGEA
                     WEEAVTGCLTVLCRRVSGQPWRRSLRDLVTTYLERPDRDDTAVFDTRLGLAVLDVVGSG
                     KDPVARLVVTELHRRTIKTTDGYAAREVLSHPLFIALATDREARDCRALLHACSLEAGV
                     LPTELGDQLTAALRTSDRVIRRSVARPEPHPLGVNRVQEVR"
     gene            complement(10001..10831)
                     /locus_tag="C7M71_RS22635"
                     /old_locus_tag="C7M71_022635"
     CDS             complement(10001..10831)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009322883.1"
                     /locus_tag="C7M71_RS22635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022635"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_111491365.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.3e-34, bitscore:
                     118.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPSTWRQVNVAFRDWERAEITALARLAPLLRAAEDEGALTAWFI
                     VRKHPCWRVRYQPASDGQDHIAQDLDMLAAEGCIGGWTETIYEPEIHAFGGAEAMASAH
                     RLFHRDSRSIIDILGSEAGKHRRETSLMLCSLMMRSAGLDWYEQGDVWARVAAHRALPP
                     GAERDSHDQLHTAVRRLLSVDLQYAVQPDGPLAHVAGWACAYTDAGRELADLTASGQLH
                     RGLRDVMAHHVIFAWNRIGLPYPMQATLTAAAKTVVFGPDPTSERSVKDRVETP"
     gene            complement(10850..12094)
                     /locus_tag="C7M71_RS22640"
                     /old_locus_tag="C7M71_022640"
     CDS             complement(10850..12094)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123797.1"
                     /locus_tag="C7M71_RS22640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022640"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_111491363.1"
                     /sec_met_domain="LANC_like (E-value: 2.3e-38, bitscore:
                     130.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTALASTALSTADRLADALADPKTVWPGGRPDGGRAWPQSLAG
                     GASGIALLHIERARTGHGDWDTAHTWLATAVHGEVSAAANANLYFGAPALAFIMHRVAG
                     ASSRYLPVLERLDAATLTVTRNRLAAAHHRIDRAERPPMEEFDLIQGLSGLGAYHLSRH
                     PRHEITQDALAYLVRLTEPMPDPSGLPPWWMNVAPTGAPHAEYPGGHGNFGLAHGIGST
                     LSVLSKALLHGLTLPGMADAVERICAWTDQWRQGDETSPWWPGQITVEQTTDGHVHSGL
                     RPRPSWCYGVGGTARAQQLAGLALGDPARVQAAESAILAALRDPLQLAKLPEIGLCHGM
                     AGLLHAAWRMATETDNPEIAAELPYLASRLITALDRSDHDPELLDGAAGAALALHTIGT
                     GSALAPHWDTFLALA"
     gene            complement(12091..14994)
                     /locus_tag="C7M71_RS22645"
                     /old_locus_tag="C7M71_022645"
     CDS             complement(12091..14994)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123798.1"
                     /locus_tag="C7M71_RS22645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022645"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_111491362.1"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.2e-18,
                     bitscore: 65.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.9e-108,
                     bitscore: 360.7, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.2e-27, bitscore:
                     93.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRCVDAAVVRAAAWHPDHRTVWPDLVSTSANTMSWRAWLQQIWQ
                     ATDFAMAVTAASPDLASRVEQICADRSLPAPAVRRTVLAVLRYLLRARTRATPFGLFAG
                     VGAARIGTMPALRVGTRHHAVPRPDAARCTALIGRFEQHPALRPYLLLLTSTLAVERDG
                     HVVIEHRPSGTTDGGPEHVHVRVTAPVREALDGARTPILWSDLAAKLSAGFPSAPLAAI
                     DKLLEGLVKQRVLLTSLRPAMTVTDPLAALLDHAQHLTPAEAAEIRETPGTALDLRMDW
                     DLTVPKAVVQEAAAAAKALTRLASRAALTGWPEWHGRFLERYGPRATVPVLDAIETLGY
                     PPGFLGATTAPTPSPSPERDSRLIRLAYAAGVQRRLEVELDDAALEELATTDPDHPVQP
                     STELTVRIDAASVAALQQGEFALHVVGVARSAGATAGRFLGMLDNEDRRRMTEVYAGLP
                     GVHRSAIVAQISSTPLSVRAENVARAPQATELVISLGDYQSPDTSLVPVTDLAVTADAE
                     QLHLVSLSRRRPVHTLLLNAVDLGHHSHPLARFLAEAPVALAVPCTGFMWGTAASNLPF
                     LPALRYGRTILSPARWLLTSEDLPAASAPWPQWDEALTQWRHDVQLPERVYLSEADQCI
                     ALDLAEPSHRALLRTHLDRDGKVTLRPAPKPQDLGWTGGRAHEVAIPLVADQNVAPVRA
                     PGHVVSREHGHLPGCDNRVYLQLHGHRDRQNPLLARHLPTLLEELGAPQWWFVRYRDPD
                     NHLRVRLMCAPGALGSVFEHIGEWTRRLRRHGLITHASVETYHPETSRFGGPTAIDAAE
                     RYFAADSAAALAQLAAQAGTGVLDARAMTAASMVDIATGLLGDSAAAMHWLIEHTRTTP
                     AAPPRAVYRQAVDLVNTRPADLSKAIATAWSARRGALTAYRRVLTGAAMQPQDLLPDLL
                     HLHQVRMHGPDLPEERTHLHLARAAALSWTARARRTP"
     aSDomain        complement(14269..14535)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C7M71_RS22645_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.00E-20"
                     /identifier="RREFam001.1"
                     /label="C7M71_RS22645"
                     /locus_tag="C7M71_RS22645"
                     /protein_end="242"
                     /protein_start="153"
                     /score="65.2"
                     /tool="antismash"
                     /translation="TSTLAVERDGHVVIEHRPSGTTDGGPEHVHVRVTAPVREALDGAR
                     TPILWSDLAAKLSAGFPSAPLAAIDKLLEGLVKQRVLLTSLRPA"
     gene            complement(15079..15261)
                     /locus_tag="C7M71_RS22650"
                     /old_locus_tag="C7M71_022650"
     CDS             complement(15079..15261)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009322874.1"
                     /locus_tag="C7M71_RS22650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022650"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_111491361.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 3.7e-17, bitscore:
                     60.4, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVQMEPPVAPAQPTAEQQDLTGFDLDITIVEGGPAADQLIRLTD
                     DGCNSTCATACVSCP"
     CDS_motif       complement(15148..15261)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MTVQMEPPVAPAQPTAEQQDLTGFDLDITIVEGGPAAD"
                     /locus_tag="C7M71_RS22650_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15079..15147)
                     /prepeptide="core"
                     /locus_tag="C7M71_RS22650_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-1.70"
                     /molecular_weight="2181.5"
                     /monoisotopic_mass="2180.0"
                     /core_sequence="QLIRLTDDGCNSTCATACVSCP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTVQMEPPVAPAQPTAEQQDLTGFDLDITIVEGGPAAD"
                     /leader_location="[15147:15261](-)"
                     /alternative_weights="2199.5"
     gene            complement(15329..16534)
                     /gene="fxlM"
                     /locus_tag="C7M71_RS22655"
                     /old_locus_tag="C7M71_022655"
     CDS             complement(15329..16534)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014138947.1"
                     /locus_tag="C7M71_RS22655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022655"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_111491360.1"
                     /sec_met_domain="PCMT (E-value: 3.3e-40, bitscore: 136.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAIDDSTVRDPDGLRADMVRALRDQDGIKSEPVAAAFAAVPRHQ
                     FAPEAPLELAYDLHRTVPVKKDEHGLDISVMSAAHLQAVMLEQAGIEPGMKVLEIGSGG
                     VNAAYLQELVGPDGDVTTVDIDRDIIDRARLCLDNAGYTQVKTVVADGECGVPDGAPYD
                     RIMVTAAAWDIPPSWISGLAEKGRLVVPLTVCGTTRSIAFDRDRDGLLSRSYSLAHFVP
                     MQGEGAAEERKAMLRDGVALRTDDVRVPLNAQALDHALDTPRLERWSGAAYDLPDELEL
                     YLTLNLPSVARLHADKEVIERGLIEASARLGVPALVSEDSIAYRTRRENGDTGGFESGV
                     VAHGPQAESLADEYVKLLRRWAHDHRRRGAATFRYLPGPAPSPLPRDAVRRRHGIVTAT
                     WR"
     misc_feature    16630..16645
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.07"
                     /tool="antismash"
     misc_feature    16848..16862
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.14"
                     /tool="antismash"
     gene            16897..18159
                     /locus_tag="C7M71_RS22660"
                     /old_locus_tag="C7M71_022660"
     CDS             16897..18159
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477435.1"
                     /locus_tag="C7M71_RS22660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022660"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_229758859.1"
                     /transl_table=11
                     /translation="MTLEELARLCRRAAEKGGLRSGIDRQRVWKWENRQAEPSPESELL
                     LADALGVPAEDVELFDWPDWLPGRDLPRPFGAAHTVRALREAQGTAMDRRTFVTYNALS
                     LAGLAAAWARTEPGRLTAALNGKTVDPELVDVLEANVSQLTTLPTEQRQHTANLLDAHL
                     TTVTGLIEKGRYSEATGRRLYLLAASLATTWGWYRFDQGRHSAAARLWDAALHSAHVAG
                     DRDFGAGVLSDFAYQSTWLGNPKAALSPLGHALSYTSHPTARSLLFLRRARAHAALGER
                     SDCYRDLTAAENELSITASEPAPRWCAWMSVADLAVDSGRCMLDLGRPDLAHPRISGGV
                     SLLPRARDKTRGIFLAYEARSLLESREVEQALAVSSEALELATRIGAERCVTLVRGLAP
                     GFTRHKQVDSVPEFLERLRTC"
     gene            18296..18556
                     /locus_tag="C7M71_RS22670"
                     /old_locus_tag="C7M71_022670"
     CDS             18296..18556
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007499625.1"
                     /locus_tag="C7M71_RS22670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022670"
                     /product="hypothetical protein"
                     /protein_id="WP_229758860.1"
                     /transl_table=11
                     /translation="MYEALLKGGSLVDVVAIMEALAEQGITVLFKADAERMAERRKPWT
                     FVASGAPLRDDILVRTDAASVEQCLKACLPRLRELGFSLPE"
     gene            complement(<18664..19076)
                     /locus_tag="C7M71_RS22675"
                     /old_locus_tag="C7M71_022675"
                     /pseudo=""
     CDS             complement(<18664..19076)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050768036.1"
                     /locus_tag="C7M71_RS22675"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="C7M71_022675"
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTHANAPLTIEGRRRLVERCHSCPIAHVAAEVGVSRACLSKWKNR
                     HDTYGEAGLRDRSSVPHSSPTQTPPEVIERIERLRRDNKWSARRIALELASQGMRISER
                     TVAGGCRAWASITAGSSTPTALPIGSGSVRQPT"
     gene            complement(19073..20251)
                     /locus_tag="C7M71_RS22680"
                     /old_locus_tag="C7M71_022680"
     CDS             complement(19073..20251)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) Chlor_Efflux_Pump"
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020139699.1"
                     /locus_tag="C7M71_RS22680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022680"
                     /product="Cmx/CmrA family chloramphenicol efflux MFS
                     transporter"
                     /protein_id="WP_111491370.1"
                     /transl_table=11
                     /translation="MPLALYLLAMAVFAMGTSEFMLAGLLPDIASDLDVTVGTAGTLTS
                     AFAMGMIVGAPLMAVLARNWPARSSLLGFVLVFLASHAMGAATSNFPVLFATRVVAALA
                     NAGFLAVAMTTAAALVLPDKRGRALAVLLSGTTVATIAGVPGGAVLGTLLGWRATFWAV
                     AALCLPAAIGVLTGIPARPVEADESEGPTLRAELAQLKSPRLLLVMLLGASVNAATFAS
                     FTFLAPVVTDTAGLGELWVSVALVLFGVGSFVGVTAAGRLSDQRPGLVLAVGGPLLLIG
                     WLALALLADKPVALLALVFAQGALSFALGSTLITRVLYEAAGAPTMAGSYATAALNVGA
                     ALGPLIAATTLRSTVGDLGPLWTSGLLVTVALLIAFPLRTVVADGRSTEVLQ"
     misc_feature    complement(20553..20569)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.01"
                     /tool="antismash"
     misc_feature    complement(20607..20625)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.01"
                     /tool="antismash"
     gene            20611..20958
                     /locus_tag="C7M71_RS22685"
                     /old_locus_tag="C7M71_022685"
     CDS             20611..20958
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019545939.1"
                     /locus_tag="C7M71_RS22685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022685"
                     /product="VOC family protein"
                     /protein_id="WP_111491357.1"
                     /transl_table=11
                     /translation="MAVRRVVPNIQSGAAQESREFYGLLGFEQVMNHGWIMTLASPSSP
                     AAQISFMTSDRTAPVNPDMSVEVDDVDAAYAVMRESGAEIVHPLQDEEWGVRRFFVRDP
                     GGRVINVLGHR"
     gene            complement(20992..>21243)
                     /locus_tag="C7M71_RS33260"
                     /pseudo=""
     CDS             complement(20992..>21243)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013752.5"
                     /locus_tag="C7M71_RS33260"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SYLRRRRIECTIPEKANQVRNRKKLGSRGGRPPAFDKDDYKERHA
                     VECGINRLKRHRAVATRYDKLAVRYEATVLVAAINEWL"
     gene            complement(21676..21807)
                     /locus_tag="C7M71_RS22695"
                     /old_locus_tag="C7M71_022695"
     CDS             complement(21676..21807)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020551879.1"
                     /locus_tag="C7M71_RS22695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022695"
                     /product="hydroxybenzoate 3-monooxygenase"
                     /protein_id="WP_229758861.1"
                     /transl_table=11
                     /translation="MHNAGFTGYEGEFRKQVARAELQRQFTSDAANKLFSELTAGTN"
     misc_feature    complement(22209..22224)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.09"
                     /tool="antismash"
     misc_feature    complement(22301..22314)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.39"
                     /tool="antismash"
     gene            22371..23261
                     /locus_tag="C7M71_RS22705"
                     /old_locus_tag="C7M71_022705"
     CDS             22371..23261
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0018576 - catechol 1,2-dioxygenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009712 - catechol-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431467.1"
                     /locus_tag="C7M71_RS22705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022705"
                     /product="dioxygenase"
                     /protein_id="WP_111491355.1"
                     /transl_table=11
                     /translation="MSIDLTETSITEAVQRTFDGAEDERVKELFICLVQHLHDFTREVR
                     LTGAEWFKVMDFLERVGKICNPTRQEYVLLSDILGLSVLVDLIHHPGIGSVTDSTLLGP
                     FYVEGRPTAENGSDISGGVAGTPLFFNGRVLDPEGNAVAGARVDTWHSDGEGFYDVQMP
                     ERLHGRLAMRALLTTDDEGRFWYRSVAPRYYPVPTDGPCGEILRAANRSPMRPEHLHFW
                     LHAEGFEPLITMLVRRDDPYVDRDAVFGVRRSLVVDFVQRDAGETAPDGTRMDEPFQTV
                     ERTFVLARTERALPH"
     gene            23319..24296
                     /locus_tag="C7M71_RS22710"
                     /old_locus_tag="C7M71_022710"
     CDS             23319..24296
                     /NRPS_PKS="Domain: PKS_ER (19-323). E-value: 1.2e-32.
                     Score: 105.2. Matches aSDomain:
                     nrpspksdomains_C7M71_RS22710_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431468.1"
                     /locus_tag="C7M71_RS22710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022710"
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_111491353.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 1e-18, bitscore:
                     66.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALRFERFGGPEVLGVEEVADPVAGDGVAVVAVKAASINPSDVL
                     AVSGRMEDTTLPRTPGRDFAGVVLEGPDDWVGAEVWGTGGDIGYSLDGSHAERIALPVS
                     ALARKPVTLDFAEAATVGVNFVVGWLGAVETAELAEGETIAVFGVSGGVGGAVAQIARA
                     VGARRIVGVAPHAPAPGTPAAEAIDAFVPFDADTDVPAEIRRLTGGRGADVVYDAVGGV
                     TTPSAVASLAHRGRLVVISAIGTSTAEVDLRDFYHRELRMLGVDSRKLDVTASAERLKR
                     ISPHFERGEFRPLPIVQTFDLDHGPDAYRAVAEKTVRGRAVIQP"
     aSDomain        23376..24287
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C7M71_RS22710_PKS_ER.1"
                     /evalue="1.20E-32"
                     /label="C7M71_RS22710_PKS_ER.1"
                     /locus_tag="C7M71_RS22710"
                     /protein_end="323"
                     /protein_start="19"
                     /score="105.2"
                     /tool="antismash"
                     /translation="VADPVAGDGVAVVAVKAASINPSDVLAVSGRMEDTTLPRTPGRDF
                     AGVVLEGPDDWVGAEVWGTGGDIGYSLDGSHAERIALPVSALARKPVTLDFAEAATVGV
                     NFVVGWLGAVETAELAEGETIAVFGVSGGVGGAVAQIARAVGARRIVGVAPHAPAPGTP
                     AAEAIDAFVPFDADTDVPAEIRRLTGGRGADVVYDAVGGVTTPSAVASLAHRGRLVVIS
                     AIGTSTAEVDLRDFYHRELRMLGVDSRKLDVTASAERLKRISPHFERGEFRPLPIVQTF
                     DLDHGPDAYRAVAEKTVRGRAVI"
     gene            complement(24283..24852)
                     /locus_tag="C7M71_RS22715"
                     /old_locus_tag="C7M71_022715"
     CDS             complement(24283..24852)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387262.1"
                     /locus_tag="C7M71_RS22715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_022715"
                     /product="hypothetical protein"
                     /protein_id="WP_229758862.1"
                     /transl_table=11
                     /translation="MPDDFLPGVDTASPGCSVKDSFATLDLTSYGFGVLFHAQWIHRPA
                     GLPVAAAPGLRTERVATAARLRDWQDAWHGGAGAPDVFRPALLDDPSVLVLAVLDGDDL
                     AGGAVLNRGSGPVGVSNLYATDPGGTAAIWSSAITAAADHFPGLPLVGYERGDGLTPAL
                     AGGFTVLGPLRVWLHSSSSRRRLRVG"
ORIGIN
        1 cggcaagacc tcgctggtgg acgacccggg cgagatctgc gccatgctct gcttcgccag
       61 gggatggcac cagagcacca ccgacaaggc ccagctggac cagatcgagt ccttcctgat
      121 cgacaagctg gccccgcaca tcgccgcctt cgactcctcg cccggcagca gcgcgatccc
      181 gcagggcacc cacgccctga tgcactgctg gaacggcgac gcccggcgcg gcatcctcgc
      241 cagcagcgag caggaccgct ggaagtgggt gctgcccggc cccaagacca acctctggat
      301 ggacaactgg gcgatcgtca agggcagccc caacgccgac gccgcccatg agctgatcga
      361 ctacgtgctc gacccggccg tggccatcaa gcaggtggag ttcgtcggct acggcaccgg
      421 cgtcaacggc accgaggagg aggccaagcg gctcaagctt gagctgatcg acatgatcag
      481 cccctccgcc gagcagctcg ccaccatgta caccggcgtc atcaacaagg gccaggagcg
      541 ccgcatggcc atcgtcaaca ggatgaaggc cgaggccggc gcatgagatc cgccgaccgc
      601 cgcagccccc gtgcagcgcg gcgagccctc ccaccgggcc tcttcgccgc gcccaccctg
      661 gcgtggctcg cgctcttctt catcgccccg gtcgggctgg tcttctggta ctccctcggc
      721 cgaaagccgg ggctgtacca gacccactcc aatgacgtgc tcaccatggg ccgctaccac
      781 gaggcgctca gcgacacctt cctgaccagc ttcatgggca ccctgcgcat cggcctcgcc
      841 ggtaccgcgc tctgcctggc gatcggcctc cccttcgcct actggctggc ggtcaaggtg
      901 cggccccagc ggcgcttcgt cgtactggcc ctggtgctgg tgccgttctg gaccaacttc
      961 ctgatccgca ccatcggctg gcaggtcgtc ctctcacccg agggcttcgc ctcccggacg
     1021 atgcagggcc tcgggctgat cgacaagccg ttctcgatgc tcttcacccc gggcgccgtg
     1081 ctgctgggcg tggtctacaa ctacctgccc atgatgattc tcccgctgta tgtcgccctc
     1141 gaccggatcg acggctcgct gcgcgaggcc agcaaggacc tcggcgccga ccgctggcgc
     1201 accgcactcc agatcaccct gccgctcgcc cgaccgggca tcgtcgccgg gctgctcctg
     1261 gtgttcatcc cgctgatggg cgactacgtc accgcgtcgg tcctcggcgg cgcccgcggc
     1321 aacatggtcg gccagctcat cgccagccag ttccagcagg gccagaactg ggcgctcggc
     1381 tcggcgatgg ccatcgtgct gatccttgtc atcgccctga ccatcctggc caccgccgtg
     1441 gccggcatcg cctgcacctg gcttctcacc caccggcgcc gccgcgagct cgccgggatc
     1501 gcagaaggga gccccgcatg agcgcgcggc ggaccgtgga ccgggccctg aacgcctggg
     1561 gcctcctggt gatcgcattc ctcttcaccc ccatcgccgt catcgtcgcc tactccttca
     1621 acaccgggcg gctgctggcc tcctgggagg ggttcgggct cgacgcgtac tcctcggcgc
     1681 tcgccaacga cgacatcctc tccgccgtct ccgtgtcggt gcggtcggcg gccggcgcgg
     1741 cggtgatcgc cgtggtgctc ggcaccctct gcggctacgc actggcccgc caccccggga
     1801 gccgcgtcgg gcggctggtc accgtgctgc tggcgctggt cctggtgacg ccggagatcg
     1861 tctccggtgt ggcgctgctc ccgtggttcg tctccctcgg cgtggactgg aacgtcaccg
     1921 tcttcaacag cggatgggtg cgcctcgtcg tcgcccactc gctcttctcg acggccgtgg
     1981 tgaccttcct ggtccgcgcc cgggcccagg gcatggaccc ctcgctggag gaggcggcgg
     2041 ccgacctcta caccccgccg ctgcgccgct tccgctccat caccctgccg ctgctgctgc
     2101 cgtcggtgct ggccggtggg ctgatggcgt tcacgctgag cctcgacaac acgatcatct
     2161 ccgcgttcgt ccaggtctcc ggctccacgc cgtggccggt ctatgtcttc agcgcggtac
     2221 gggccggtct gcgcccggaa ctcgccgcga tgtcggcggt gatgctgctg ctgaccctgg
     2281 ccgcgctgac ggccgtggcg ctcgtgctgc gacgcgtcgg cggttccaag gacgccgtca
     2341 acgccctctc cggcgtccac tgaccccgcc cccaccccgt ccccagcccc gaccccccat
     2401 cccccgcaga gagcgagagt gcaccaccga tggcggcaaa cctgctgatc cgcaacgccc
     2461 acctgccgct gggcgacccg gaggccgcgt cctggtcggt ccgggtcgcg gacggccgga
     2521 tcgccgaggt cgtcccgacc gaggtcggag tccccgaggc cccgcccggc accgagacgc
     2581 tggacgcggc aggccgctcc gtcctgcccg ccttcgccga ctcccacgtc catgtgcccg
     2641 agtccggagt cgaactgctc cggtgcgacc tcaccgtctg cgagagccgg gacgaggtgc
     2701 tgcgtacggt cgccgactat gcgcggtccc acctcggcga ggagtggatc atcggccggg
     2761 gctgggcgct gccccacttc gccgaacacc ccccgacccg gcaggaactc gacgccgtct
     2821 gcggcggacg ccccgcctac ctggccaacc gcgacggcca cagcgcctgg gtctccaccg
     2881 ccgcactgga ccgggtgacc ccggaactcc tccgcaaccc gccgcccggc ggccgggtcg
     2941 accgcgacgc cgacggcagc cccaccgggc tgctccacga gtcggccatg caactcgtct
     3001 ccgacctggt cccggcggtg ggcgcggagg acctgcggcg cggcctgctg gaggcgcagc
     3061 ggcggatgtt ctcctatggc gtgacctcgt ggcaggacgc catcgtcgga ccgttcgtcc
     3121 ccaccaccga catctacgac gtctaccgcc gggccgccgc cgacggcagc ctgcgcgccc
     3181 gggtcaccgg cgccctgtgg tggccgcgcg acgcctccgc cgacaccctc gccgggctgg
     3241 tcgagcagcg ccgtggctgc ccgccggact cccggttctc ctgcaccgcc atcaagatca
     3301 tgtacgacgg ggtgtgcgag acccacaccg ccgcactctc ccgcccgtac gtcggcatcg
     3361 cgggcgccgg gaccggcctg accttcttcg accccgccga catggcgcgg gcggtgccgc
     3421 agatggacgc cgcagggttc gacctccact tccacgccat cggcgaccgc gcggtcagcg
     3481 agtgcctcga tctggtggag gcggcgcagc aggccaacgg cccgcgcgac cggcggcacc
     3541 aactcgccca cctccagatc gcggacgacc gcagcgtggc gcggatggcc gcgctcggcg
     3601 tcatcgccaa cgtccagccg tactgggccc aggccgaccc gcagatgctc gatatgacga
     3661 tcccgtacct gcccggcgag ctggccgcct tgcagtaccg attccgcacg ctggaggacg
     3721 cgggcgtccg ggtcgccttc ggcagcgact ggccggtcag tacgccgaac ccgctggact
     3781 ggatccatgt cgcggtcaac cgcagccacc ccgacgagcc gggcgccccg ctcttcgccc
     3841 cggaggaggc gatgagcctg cgttcggcgc tccgggcggc cacggcgggc tccgcccatg
     3901 cgctgcgccg cgagcatgaa gcgggcacgc tggagccggg cgcccgcgcg gacctggtgg
     3961 tcctggaccg ccgcctggac gagaccgtgc tcggggagat cagccggacc cgcgtcgacc
     4021 tgacgctgat cgacggcgaa cccgtctgga cgaggtgacc cctggggcgg caaaggcagc
     4081 ggccccgtcg gccacttcgg gcggcgacgg ggccgtgggc aggggggagt cactgcgcgg
     4141 cggcgaactc cacgaagtcg gcccacgcct gaggcgtgaa ggccagctgg gggccctgct
     4201 tgtccttgga gtcacggaca tggacggtgg aggggcaggc ggcgacctcg acgcactggc
     4261 cgcccgcgcc gccgctgtgg ctggacttgt gccagccgac ggcgacctcg acgcaggcgc
     4321 caccctcggc accgctgtag ctggacttgt accaggtcaa ctcggtggag ccggggatgg
     4381 tttccttgac gttcatagtt ctcccagcga cttctcgatg taggccagcg actcccgggg
     4441 agtcagggcc tgtgctcgga tgatgccata gcgtgaggca atggcgcgga cctcttccac
     4501 gtcggtgacg attgtgctac ggccctgccc ctccatgtac accacctgct gccggccctt
     4561 gggcgtgatc aggtggaacg ggccatccat cccggcgtgg tcctcccggt cggtgggcat
     4621 cacctggatc tccacgttcc gcagctgccc gacctcaagc agccgtttga gctgcccacg
     4681 cagcacctct ttgccgccga tcgggcggcg cagcaccacc tcctcgatga caaaccccag
     4741 cagcggcgcc gggcgccggg tgaagatctc ctgacgggcc aaccgggccg ctacgcgctg
     4801 ctcgatggtc tcctcgtcca tcagcggtcg gcccgtggcg aagacggccc gtgcgtagcc
     4861 ctcggtctgg agcagcccgt tcatgaccag gctgtcgtag gtgtacagct cgaccgcctc
     4921 cgcctccagc cgaacgtagt cgcggaagaa ctccgggaag cgcgcgctcg ccaccgaccg
     4981 cttgagcacg agcagcatgc cgcccgcgtt cagcacttcg tccgccttgt cgatgaactc
     5041 cggctgggcg acccgccgtc cctgttcgac cgaggagacc agatcctcgg agtagcccag
     5101 cttcttgccc agttccgcct gcttgagccc cgcccgctcg cggagcagct tcacctgctt
     5161 cccgaagccc ttgaggatct cgattcccga gtcgtcctgt gcgttgacgg ccactttccg
     5221 ccacctcctg acgtaccgtc tgcttaacgc agctcgcttc cccaccgtca cgaacgcccc
     5281 cgcgtacgcg ccacgttccg ccgccgtaca ggcactctcc gtactgtggg tcgtgctggt
     5341 caggctactc agatcgggcc accgttggag gcatgaagtc cgaatttccc cctaccgaaa
     5401 tcactctccg tgcccgagat ttcgcccagc gcttcagctc cacccgccat ggggcccgct
     5461 tggcacggca tatgacgatg cgtcggctgg ccgattgggg gtggccgccg gtcggcgagc
     5521 tgtccacggc ggcggcgctg gtggtggccg aactggcgtc caacgcggta ctgcacggcc
     5581 ggctgcccgg gcggtacttc gaactgcggc tggccgtctt cccggacgcc tcggtcctgc
     5641 gcatcgaggt ctccgacgcc aggggcgaac gccgtcccga ggcacccacc cacatccccg
     5701 ggccggaggc cgagcgcggg cgggggctgc tgctggtgga ctgcctggcg ctgcggtggg
     5761 gtgtgctgga ccggctcccg gtcggcaaga cggtctgggc ggaactggag gcggcggcgt
     5821 gaaggcggac cgggcggccg agcgggagcg ggtccggcga ttgcgcgagc aggggcggga
     5881 ggtggtcgcc gaactccggg ccgccaccgg cagcatgggg ctggacttct gcgagctgca
     5941 tctgcgcgag ggcaccgggc cggacgcgga gcccagcatc gcgtggggct gcaccaccgt
     6001 ggacaccgcg caccgcttcc tcgacctgct ggcactgctg gacgccaccc gggaggcgga
     6061 ggcggcgctg atggcgcgga tcttccggcg ctacccgcag ctccggtcgg gcctgcaccc
     6121 gcacacgcag ccgtctccgt ccccgtcctc gccctcgtcc tcgcccccgt ccccgtcgcg
     6181 gttgcggtac tagcgggcgg cgacggtccg gacgaccatc cggaccgggg tgcccggggc
     6241 cttgccgcag gactccgggc ggggcggctc cgagacgccc cgggcgacct cgacatccca
     6301 ggtccggccg tcgccggtgt gccggaccag gacctgccag ccctccgggg acggttgctg
     6361 ccgctcgacc gtgagggcgt ccgcgcgctc ttcgccgatc aggcggcgta ccgccagctc
     6421 ggcggcctga ccgggccggt cccagcagga ccggccccgg cacccctcct ggaccatccg
     6481 cccgtcggcc gcgcccgcca gcacctcctt ggcggcggcg gcgctgagcc tgccgtacgc
     6541 atagccgtac ggcagcacca gcatggtggg ggagaagcgg tggccgccga ggtgggtgac
     6601 ctcccacacc tcgctgtggc cggaggcggc cagttcggcg gcgagcgggc ggccgagcag
     6661 ggcgcagcag cggtcgcggc ggccgttggt gcacaccagg gccagcgggt cgccgtggtg
     6721 gtcgctgccg aagctgccgt gtacgcccgc gcccagcgcc gcgaagtcca gcgccgccag
     6781 ttcggccggg tcggcgacgg tggcccgccg cacccaggac gcgcccgggg cggtgtgcgc
     6841 cacgaccacc tcgcgccggg ggtgtccggc ggacggcggg tcggcgtgcc gtccgggcct
     6901 gcggatcagc gccacccgta cgccggtccc gtccgccgcc cggtccagcg cccggccgac
     6961 ctcggggtcg aggtggctct ccttgagcgc cttggccccc cacggcccgg gctgctccag
     7021 cagcagccag gtggcggcgg tcgccgccgt ggcggccagc ggctcggtca gttcacggga
     7081 gagggccgta caggtgtcca ccgggccacc ctactccggg cccggaaggg gcccggaggg
     7141 ctggagagcg ggcctgcgga tcattccttt gtgcagtacg ggctcttccg gatggcctcg
     7201 aagtcggcct tgaagctgtc gtagacggcc gcgttgtcga tcttcagcag ggtctcgtca
     7261 tgggagcgaa gagtggggta ggtgtagttg tggcttccgg tgaagaccac cttgcggttg
     7321 gcgccgccga gataggtgcc ctcgatgatc atgtacttgt cgtggatgcc gatggtccgc
     7381 gtggtcccgt cggcattggt ggcggtgccg tcgcaccgcg tgatggagct gatcttcccg
     7441 gcgaggatgc cctgcacctt ggtcccgtag ttgccgtccc cggcgttgcg gatgaggtcc
     7501 acccggcagc cggccttctt cagctccacc atcttgtcgg ccacctggga gcgggtgaag
     7561 gcgtacatgc cgatccggat ctgggtggcg ccgcccgcgc agtccacatt gcccagcagg
     7621 gagacgatcg tgtccgtgct gggatcggtc gagtaggtgg tgcccgacga ctcctggcgg
     7681 gggaagaagt acgtcttgta cgggccgctc tgctccgtct tgtagtaggt ggcgagcccc
     7741 gagccggagg agccgtacgt cttgaggtcc tgccagtagg cgcggtaggc cgagtagagc
     7801 ccggagccct cgtccgggat ggtcacggcg ttgttgtaga agttgcggcg ctggctggtg
     7861 gtcaggttcg ccgaggtctg gaacaccaca ttggccgtac tgccgacctg ggagaacagg
     7921 aagaacttgt tgtggttgat ggcgggatcg ccgaggttgc ggttggcgat gcagccacgg
     7981 gtggccgggc aggccagcac ccatgaatcg gccgacagat tggtgcccag acccgccgtg
     8041 agcaccgggt actccgtacc gtccgcagtg acggcgtcac cgtcgacgat caccttgacc
     8101 ttcacacccc gctgcttggc ggcgatcagc gcgctgctca ctccgccgtc cgtgaagagg
     8161 tagatggagc cgttgatctc ggatccctgc ggagcacggt tgacgaggga tatcagctcg
     8221 ttccgaatgg cgtcctgctc cgccgccgtc cccaccggat tgttgaacgt ggtggtgagg
     8281 ggcacggtgt cgtcggctgc ggcggccgtc cccggcactc ccagcagggt ggtgcccagc
     8341 agaacggcta tcgcaggtgc gatgtagccc atcttcacgt tcggctcccg tcatgtcgct
     8401 gccagcttga tcggcaacgt acatgactga tcgtcatatg agaacacctg ttccggtgcc
     8461 gggtcacgcg tcgggtcagg cgtcgggtca ggcgcggggg agggcgaggg tgggcagtcg
     8521 ggggtgcctg aggtgctgcc cgtcccggtc gatgtccaga cggaagctct ccggcggcgg
     8581 gcagccggcc tggtcgtacg cgtcgagcac cgcctcgacc tgggggctga gttgggcatc
     8641 gggaacggcg cactgggcga ggaagcgcgc aaagaacgcc tcagcggtgg cagcggtgat
     8701 gcggtcggga acatgccggg cacggcggcg ttcgccgccc agcagcgagg cccagtggcg
     8761 ctccgccccc agaggccggg aggccaggct cgttgtggtt tggctcctgg tcgctctggt
     8821 tgccctcgtt cccgacgctc atgccgaacg ggccgcgcac ctgggcgctc gtcagcggac
     8881 ctcttgaact cgattcaccc ccagggggtg tggctcaggg cgggcgacgc tacggcgaat
     8941 gacgcgatca cttgtgcgta gcgcggccgt gagctggtcg cccagctcag tggggagcac
     9001 cccagcttcg agtgaacaag cgtggagtag agcacggcag tcccgcgctt cccggtccgt
     9061 ggcgagggca atgaacagtg ggtgagaaag gacctcccgg gccgcgtagc cgtcggtcgt
     9121 ctttatcgtc cggcggtgca gctccgtgac caccaggcgc gcaaccgggt cctttcccga
     9181 gccgaccacg tccagcacgg cgagtccgag tctcgtatcg aagacggccg tgtcgtcccg
     9241 atccggacgt tcgaggtagg tggtcaccag gtcccgcagg gagcgtcgcc aaggctgccc
     9301 tgatacgcgg cggcacagca cggtcaagca gcccgtgacg gcctcctccc atgcctctcc
     9361 ggggactgca tgggccagga gactgccggc ttcgagggtg ttcccgctcg tcagagccgc
     9421 gaggacggcg acttgccggc cgtcgagcat gcgctgcccg acgccgcggt gcgtctcgat
     9481 gtgggcgagc gcttcgcccc agcggccggc cgtggtcagc gcgcgcgtgc cgtcggcgag
     9541 gagcacactc cacagccagg aacggacatc atggcggtcg gcggcgttcg ctacgaggtc
     9601 cgcaggcacg gtgatgccct cgacccggat ggcgctcccg gtggtcacgg catcgaacag
     9661 ctccagcagg cgctgacgac cgtcgtcggt ttgtccggcg cggagttgga ggcgcgcgag
     9721 gttgacgagg ggttcgaggg cgcggatcgc ggcactgctg ggcaggggcg cggcgtgcag
     9781 gtaggcggcg gcgtgttggt ggcacatcgc gcgggcggtg gccgggacgc cgacgtcgga
     9841 ggcgaccagg gcggcctggt tgtagaccgt ggaggccaag ccagggtcgc cctgcttccc
     9901 tgcgtcgtct gcgagttcgg ccagcgcgtg aacgcgttgg ggcaggggga ggcaggtggg
     9961 gcgggggcga gcaacgaggg ggaagcgctg ggctatggag tcatggagtt tccacacggt
    10021 ccttgacgct cctctcggag gtggggtccg ggccgaagac gacggttttg gcggcggccg
    10081 tgagcgtggc ctgcatgggg tagggcaggc cgatccggtt ccaggcgaag atcacgtggt
    10141 gagccatgac gtcacggagg ccacggtgga gctgtcccga ggctgtgaga tcggccagtt
    10201 ctcttccggc gtcggtgtag gcgcaggccc acccggcgac gtgggcaagc ggtccgtccg
    10261 gctgcaccgc gtactgcagg tccacggaga gcagacgacg tacggcggtg tgcaactggt
    10321 cgtgactgtc ccgttcggca ccggggggta gggcccggtg ggcggcgacc cgggcccata
    10381 cgtcgccttg ctcgtaccag tccagtccgg ctgagcgcat catcaggctg cacagcatca
    10441 gggatgtctc gcggcggtgt ttgccagcct cgcttccgag aatgtcgatg atgctgcggc
    10501 tgtcgcggtg gaagagccgg tgggcggatg ccatggcttc ggcgccgccg aaagcgtgga
    10561 tctccggttc gtagatggtc tccgtccacc ctccgatgca tccctcggcg gccagcatgt
    10621 cgaggtcttg ggcgatgtgg tcctgcccgt cggaggcggg ctgatagcgc acgcgccagc
    10681 agggatgctt gcggacgatg aaccacgcgg tgagggcgcc ttcgtcctct gcggcgcgaa
    10741 ggagcggggc gagtcgagcc aaggcggtga tctcggcgcg ttcccagtcc cggaaggcga
    10801 cgtttacctg gcgccaagtg gatggattca tacggcgggc ctccagagtt cacgccaggg
    10861 cgaggaaggt gtcccagtgc ggtgcgagcg cgctgcccgt gccgatggtg tgcagggcga
    10921 gggccgcccc ggcggctccg tcgaggagtt ccgggtcgtg gtcgcttcgg tcgagcgcgg
    10981 tgatcagacg gctggccagg tacggcagct ccgcagcgat ctcggggttg tccgtctcgg
    11041 tggccatccg ccatgcggcg tgcagcagtc cggccatgcc gtggcacagc ccgatctcag
    11101 ggagcttggc cagttgcagt gggtcgcgca gggccgcgag aatcgcgctc tcggcggcct
    11161 gcacgcgtgc cgggtcgcca agagcgagcc cagccagctg ctgagcgcgg gcggtgccgc
    11221 cgactccgta gcaccaggat ggccgggggc gaaggccaga gtggacgtgg ccgtcggtcg
    11281 tctgctccac ggtgatctgg ccgggccacc aagggctggt ctcgtcgcct tggcgccact
    11341 ggtcggtcca ggcacagatt cgctcgacgg catcggccat gccgggcagg gtcaggccat
    11401 ggagcagggc cttggacagc acggacaggg tggagccgat gccgtgggcg agcccgaagt
    11461 tcccgtggcc gccgggatat tcggcgtggg gtgcgccggt gggcgcaacg ttcatccacc
    11521 agggcggcag tccgctcggg tcgggcatgg gctcggtcag gcgtaccagg taggccagcg
    11581 catcctgagt gatctcgtgg cgggggtggc ggctcaggtg gtaggcgcca agccctgaca
    11641 ggccctggat cagatcgaac tcttccatgg gaggccgctc ggcgcggtcg atgcggtgat
    11701 gggctgctgc gaggcggttc cgggtgacgg tgagggtcgc cgcatccagg cgctccagga
    11761 cgggcaggta ccggctcgat gcgccggcca cgcgatgcat gatgaaggcg agggcgggtg
    11821 cgccgaagta caggttcgcg ttggccgccg cgctgacttc accgtgcacg gccgtggcca
    11881 gccaggtgtg cgcggtgtcc cagtcgccgt ggccggtccg ggcacgctcg atgtgtagca
    11941 gggcgatgcc cgaggctcct ccggcgagcg actgcggcca ggctcggccg ccgtcgggtc
    12001 ggccgccggg ccacacggtt ttggggtcgg ccaatgcgtc ggccagacgg tcggcggtcg
    12061 acagcgcggt ggaggcgaga gctgtcgtgg tcacggtgtc ctcctcgctc gtgctgtcca
    12121 gctcagggcg gcggccctgg ccaagtgcag gtgcgtgcgc tcctcgggca ggtccggccc
    12181 gtgcatccgg acctggtgga ggtgcagcag gtccggcagc agatcctggg gctgcatggc
    12241 cgcgcctgtg agcacgcggc ggtaggcggt cagtgccccg cgtcgcgcgg accaagccgt
    12301 ggcaatggcc ttgctcaagt ccgcggggcg ggtgttcacc aggtcgacgg cttggcggta
    12361 gacggcgcgt ggcggagcgg ccggggtggt gcgggtgtgc tcgatgagcc agtgcatcgc
    12421 cgcagcgctg tcaccgagca ggccggtggc gatgtcgacc atgcttgcag cagtcatcgc
    12481 gcgggcgtcc aggacgcccg tcccggcctg ggcggcgagt tgagccagag cggcggcgga
    12541 gtcggcggcg aagtaccgct cggccgcgtc gatcgcggtg ggaccaccga accgcgaggt
    12601 ctccgggtgg taggtctcca cgctggcgtg ggtgatcaag ccgtggcgcc ggagccggcg
    12661 ggtccactcg ccgatgtgct cgaagacgct gccgagggct ccgggcgcgc acatcaggcg
    12721 aacacgaagg tggttgtcag ggtctcggta gcggacgaac caccattggg gggcgcccag
    12781 ttcttccagc agggtcggca ggtgtcgggc caggagcggg ttctgccggt cgcggtgtcc
    12841 gtggagctgg aggtagacgc gattgtcgca gccgggcagg tggccgtgct cacggctgac
    12901 gacgtgcccc ggcgcccgga ccggggcgac gttctggtct gcgaccaggg gaatggcgac
    12961 ttcgtgtgct cggccgccgg tccaccccag gtcctggggt tttggtgcgg ggcgcagcgt
    13021 caccttgccg tcgcggtcca ggtgcgtgcg cagcagtgcc cggtgtgaag gctccgccag
    13081 gtccagggct atgcactgat cggcctcgct caggtagacc cgctcaggca gctgcacgtc
    13141 atggcgccat tgggtcaggg cctcgtccca ctgcggccac ggtgctgacg cggcgggcag
    13201 atcttcactg gtgaggagcc agcgggccgg ggacaggatc gtgcgtccgt agcgcagagc
    13261 aggcagaaaa ggcaggttgg aagcggcggt gccccacatg aatccggtgc acgggacggc
    13321 gagcgcgacg ggtgcctcgg caaggaaccg ggccagcgga tgggagtggt ggcccaggtc
    13381 cacggcgttg agcagcagcg tgtgcaccgg gcggcggcgc gagagggaga ccaggtgcag
    13441 ttgttcggcg tcggcggtga ccgccagatc cgtcacgggg acgaggctgg tgtccggact
    13501 ctggtagtcg ccgagcgaga tcaccagctc ggtcgcctgt ggggcgcgtg cgacgttctc
    13561 agcgcggacg gacagcgggg tggagctgat ctgcgcgacg attgcgcttc ggtgcactcc
    13621 gggcagcccg gcgtacacct cggtcatgcg acggcggtcc tcgttgtcca gcatgcccag
    13681 gaagcggccg gccgtagcac cggccgagcg cgccaccccg acgacgtgca gggcgaattc
    13741 gccctgctgg agagcggcaa cgctcgcggc atcgatgcgt acggtcagtt cggtgctcgg
    13801 ctgcacgggg tggtcaggat ctgtggtcgc cagttcctcc agggcggcat cgtcaagctc
    13861 gacctcaaga cggcgctgca ccccggcggc gtaggcgagc ctgatgagtc ggctgtcgcg
    13921 ctccggcgac ggggagggcg tcggcgcggt ggtggccccg aggaagccgg gcgggtatcc
    13981 gagcgtttcg atggcgtcca ggacggggac ggtcgcccgt ggcccgtacc gttccaggaa
    14041 gcgtccgtgc cactcgggcc agccggtcaa tgccgctcgg gaagcgaggc gggtgagtgc
    14101 cttcgctgcc gctgccgcct cctgcaccac cgccttgggt acggtcaggt cccagtccat
    14161 ccgcaggtcg agcgccgttc cgggggtctc acgtatctct gctgcctcgg cgggagtgag
    14221 gtgctgtgcg tggtcgagga gggcggcgag ggggtcagtg acggtcatcg ccgggcggag
    14281 actggtgagg aggacccgtt gcttgaccaa gccttcgagg agcttgtcga tcgcggcgag
    14341 cggcgcgctc gggaagccgg cggagagctt cgcagcgagg tcgctccaca ggatcggggt
    14401 ccgcgcgccg tccagggctt cgcggaccgg cgcggtcacg cgaacgtgca cgtgctccgg
    14461 tcctccgtcg gtggttccgc tcgggcggtg ctcgatcaca acgtgcccgt cgcgttcgac
    14521 agcgagggtg gacgtgagca gcagcaggta gggccgcagt gccgggtgct gctcgaagcg
    14581 gccgatgagg gccgtgcagc gtgccgcgtc gggcctgggg acggcgtggt gcctggtgcc
    14641 tacgcgcagc gcgggcatgg tgcctatccg cgcggccccg accccggcga acagaccgaa
    14701 cggggtggcg cgcgtgcggg cgcgcagcag atagcgcaga acggcgagca cggtgcgccg
    14761 tacggcaggg gccggaagcg atcgatcggc gcagatctgc tccaccctgc tcgcgagatc
    14821 cggactggcg gccgtgacgg ccatcgcgaa atcggtggct tgccagatct gttgcagcca
    14881 cgcccgccac gacatcgtgt tcgcggatgt gctgacgagg tccggccaga ccgtccggtg
    14941 atcggggtgc catgcagccg cccggaccac tgctgcatca acgcagcggt acatatgccc
    15001 ctcctctggc cgcgcggttc ccggccgcgc ccatgggctg ggcgcggccg gaagccgcag
    15061 tgaacgcgat cggtactgct acgggcagct cacgcaggcg gtcgcgcacg tggagttgca
    15121 gccgtcgtcc gtcaggcgga tgagctggtc cgcggcgggg ccgccctcga cgatggtgat
    15181 gtccaggtcg aagccggtga ggtcctgctg ctcggcggtc ggctgcgcgg gcgcaaccgg
    15241 gggctccatc tgaacggtca tacatgcctc cttgggggca gttggttgat ggtgcacagc
    15301 ccggtacccg aggcggggcc cgggagtctc agcgccaggt cgccgtgacg atgccgtggc
    15361 gtcggcgtac ggcgtcccga gggaggggcg agggagcggg gcccggcagg taccggaacg
    15421 tcgcggctcc ccggcggcgg tgatcgtggg cccagcggcg gagcagcttc acgtactcgt
    15481 ccgcgaggga ttcggcctgc gggccgtggg cgaccacgcc gctctcgaag ccgccggtgt
    15541 ccccgttctc ccggcgggtt cggtaggcga tgctgtcctc gctgaccagg gcgggcacgc
    15601 cgagccgggc tgaggcttcg atcagtccgc gctcgatgac ttccttgtcc gcgtgcagcc
    15661 gggcgacgct gggcaggttg agcgtgaggt acagctccaa ctcgtcgggc aggtcgtagg
    15721 ccgcgcccga ccagcgctcc agccgggggg tgtccagggc gtggtccaga gcctgggcgt
    15781 tgagcggcac ccgtacgtcg tcggtccgaa gggcgactcc gtccctcagc atcgccttac
    15841 gttcctcggc ggcaccctcg ccctgcatgg gcacgaagtg cgccaggctg taggagcggc
    15901 tgagcaggcc gtcacggtcg cggtcgaaag cgatcgagcg cgtcgtgccg cataccgtca
    15961 gcgggacgac gagcctgccc ttctcggcaa gtccgctgat ccacgacggg gggatgtccc
    16021 aggcggctgc ggtgaccatg atccggtcgt acggggcccc gtcgggaacg ccgcactcgc
    16081 catcggcgac gaccgtcttc acctgggtgt atccggcgtt gtccaggcac aggcgtgccc
    16141 ggtcgatgat gtcgcggtcg atgtcgacgg tggtgacgtc cccgtcgggg cccaccagtt
    16201 cctggagata tgcggcgttg acaccgccgg agccgatctc caggaccttc atgccgggct
    16261 cgatgccggc ctgctccagc atcacggcct ggaggtgggc cgcagacatg acgctgatgt
    16321 ccaggccgtg ctcgtccttc ttcaccggca cggtgcggtg caggtcgtag gcgagttcca
    16381 gaggcgcttc cggcgcgaac tgatgcctgg gtactgcggc gaaggcggcg gcgacaggct
    16441 cggacttgat cccgtcctga tcgcggagtg cgcggaccat gtccgcgcgc agcccgtcgg
    16501 gatcgcggac cgtcgagtca tcgatggcag tcatccgatt acctactcct gtcgggaggt
    16561 tggtgctttc ggcagcgggc ggatacgcgc cgccaggcga cggcggcgta ctcgtcggcc
    16621 gagatcgtgt tgaacgcgtg gtccgtacgg tcgcacgcct cctcctcccg ggagccgccg
    16681 acgggcggtc tggcggacgg ggtcgagcgc cacccgtggt tccgctctgt gaggacgagt
    16741 agagcgcaac tctccgtgtc gcgagagagg cgttctgtag tcccgccgtc gtcccgcctg
    16801 tgcgcagagt aggatcccgg tcactgtgaa tgatgggatt ggcctgtgga cgatccgatc
    16861 cggcaccccc tcacatatgc gaggacacag cgcgggttga ccctggaaga gctggcccgg
    16921 ctgtgccgcc gggccgccga gaaaggcggg ctccgttcgg ggatcgaccg tcagcgggtc
    16981 tggaagtggg agaaccggca ggcggagccg agccctgagt cggaactgct gctcgccgac
    17041 gccttggggg tcccggccga ggatgtcgag ctgttcgact ggcccgactg gctgcccggc
    17101 cgcgacctcc cccgtccctt cggtgccgcg cacaccgtcc gcgcacttcg agaggcccag
    17161 ggaaccgcca tggaccgccg caccttcgtg acctacaacg cgctctcact ggccgggctg
    17221 gccgccgcat gggcccgaac cgagccggga cgcctcaccg ctgcgctgaa cggcaagacg
    17281 gtcgatcccg aacttgtcga cgtgctggag gccaatgtct cgcagctgac caccctgccc
    17341 accgaacagc gccagcacac ggcgaacctg ctggatgccc acctcaccac cgtgaccgga
    17401 ctcatcgaga agggccgtta ctccgaggcc accggccggc gcctgtacct tctggccgcc
    17461 tcgctggcca ccacctgggg ctggtaccgc ttcgaccagg ggcggcactc ggcagcggcc
    17521 cgcctgtggg acgccgccct ccacagtgcg catgtcgcgg gggaccgcga cttcggcgcc
    17581 ggggtgctca gcgacttcgc gtaccagtcc acctggctcg gcaaccccaa ggcggccctg
    17641 agcccgcttg ggcatgcgct gtcgtacacc agccacccca ccgcccgatc cctgctgttc
    17701 ctgcgcaggg ccagggcgca cgccgcgctc ggcgaaaggt cggactgcta ccgggacctg
    17761 accgctgccg agaacgagct gtcgatcacg gcatccgaac cggcaccccg ctggtgtgcc
    17821 tggatgagcg tggccgacct ggccgtcgac tccggccggt gcatgctcga tctcgggcgg
    17881 ccggacctcg cccatccccg gatttccggc ggcgtgagcc tcctaccgcg tgcccgggac
    17941 aagacgcgcg ggatcttcct cgcctacgag gcgcggagcc tcctggagtc ccgcgaggtc
    18001 gagcaagctc tcgcggtcag cagcgaagcc cttgaactcg ccacccgcat cggagccgag
    18061 cggtgcgtca cgctggtgcg agggctcgcg ccgggcttca cgcgccacaa gcaggtggac
    18121 agcgtcccgg agttcctgga acggctcagg acctgctgaa accggctgcg gcttccacgt
    18181 cgccgtcatc gacatgcccg gccacggcga ccggccgcgc acggcgcacg acgagcagga
    18241 gatcgccgcc aacgcgggca acggcctcgg gacggtcggg taggttcacg ggggtgtgta
    18301 cgaggcactt ctgaaggggg gatcactggt ggacgttgtg gcgatcatgg aagcactggc
    18361 tgagcagggc atcacagtgc tcttcaaggc cgacgccgag cggatggcag agcggcgcaa
    18421 gccctggaca ttcgtggcca gtggcgcccc tctgcgtgac gacatcctcg tgcgaaccga
    18481 tgccgcctcg gtggagcagt gcctcaaagc ctgcctgccc cgcctgcgcg aactgggctt
    18541 ttcgctgccc gagtgacgag ggcaccgccc gcgagcgtcc ccgggttcac cggccgactc
    18601 gggtgacgtc cgggagaggg cctcggggag ccgaggttgg cggccgccgt gatgagaacg
    18661 atcacggtcg gctggcgcac ggatccactg ccgattggca gagccgtcgg ggtcgaggaa
    18721 ccggcggtga ttgatgccca agcccgacag ccaccggcca cggtgcgttc gctgatccgc
    18781 atgccctggc ttgcgagttc gagcgcgatc ctgcgggcgg accacttgtt gtcgcgccgc
    18841 agtctctcga tccgttcgat gacctcgggc ggcgtttggg tcggtgacga gtgcgggacg
    18901 ctggagcggt cccgcagccc tgcctcgccg tacgtgtcgt gccggttctt ccacttggag
    18961 aggcaggcgc gcgagacacc gacctcggcg gcgacgtgcg cgattgggca gctgtggcag
    19021 cgctccacga gccgtcggcg tccctcgatg gtcaaggggg cgttcgcatg cgtcactgga
    19081 gcacctcggt gctccggccg tccgcgacca ccgtgcgcag ggggaacgcg atgagcagcg
    19141 cgaccgtgac taggagcccg cttgtccaca gcggcccgag gtccccgacc gtggagcgga
    19201 gggtggtcgc ggcgatgagt ggtccaaggg ctgcgccgac gttgagtgcg gcggtcgcat
    19261 aagagccggc catggtgggg gctcctgccg cctcatagag gacccgcgtg atcagggtgc
    19321 tgcccagcgc gaacgacagg gctccttgcg cgaacacgag ggcgagcaga gcgaccggct
    19381 tgtcggccag cagggccagg gccagccagc cgatgagcag cagcggaccg ccgaccgcga
    19441 ggaccaggcc ggggcgctgg tcggacagtc gcccggcagc ggtgacgccg acgaaggagc
    19501 cgacaccgaa gagcaccaga gccacagaga cccacagctc gcccagtccg gcggtgtcgg
    19561 tcacgacggg ggcgaggaag gtgaagcttg cgaaggtagc cgcgttcacc gacgcgccga
    19621 gcagcatcac caggagcaac cgcgggctct tgagctgtgc gagctccgct cgcaaggtcg
    19681 gcccctcgct ctcgtctgcc tccacagggc gcgctgggat tcctgtgagg acgccgatgg
    19741 ctgcgggcag gcagagagcg gcgacagccc agaacgtggc ccgccagccg agtagtgtgc
    19801 cgaggaccgc tccccctggg accccggcga tcgtggccac cgtggtgcct gacagcagca
    19861 cggccagcgc ccgtcccctc ttgtcgggca agacgagcgc ggcggcggtc gtcatggcta
    19921 cggcgaggaa tccggcgttc gcgagtgctg cgactacccg ggtcgcgaac aggacgggga
    19981 agttcgaggt ggcagcgccc atggcgtggg atgccaagaa cacgaggacg aacccaagca
    20041 ggctcgaccg tgcgggccag ttacgggcaa gtactgccat gagcggggcc ccgacgatca
    20101 tgcccatcgc gaaggccgac gtgagtgtgc cggctgtccc gacggtgacg tcgaggtctg
    20161 aagcgatgtc cggcaagagg ccggcgagca tgaactccga ggtacccatg gcgaagaccg
    20221 ccatggcaag cagatacagc gcgagaggca tcgagtggct ccgaggcgag gagaagcacg
    20281 agaaggtcat ctcgtcaccg cggccagccc cacgggcacc ctcgtccgac cgcagaatgc
    20341 ggcgcggcgg cagggctgca agctcagtgg ttcagggggc tgacggcgtg accgaaagcc
    20401 cccacccggt ctgactccgg actcgacatg gcccgcacgc tacccgaccg aggtcctccc
    20461 aggcacctcg gtttcacggg cgtggcctgc gtcagcaacg tcatgtctcg caacaactag
    20521 ggtccgttgc gaaagtgcgc gcgacgacgg acttgtcgta atactcctgg ggagacgtag
    20581 agacacgttt cttctcactt ggagtcgttg atggccgttc gccgtgtcgt gcccaacatt
    20641 cagtcggggg ccgcgcagga gagccgggag ttctacggtc tgctgggctt cgagcaggtc
    20701 atgaaccacg gctggatcat gacgctcgcc tccccgtcaa gcccagcagc gcagatcagc
    20761 ttcatgacca gcgacaggac cgcgcctgtc aaccccgaca tgagcgtcga ggtggacgac
    20821 gtggatgcgg cttatgcggt catgcgggag agcggtgcgg agatcgttca ccccttgcag
    20881 gacgaggagt ggggcgtgcg gcggttcttc gtccgcgacc ccggtggacg ggtgatcaac
    20941 gtgctgggcc accgctgacc gcctcctccg cgcccctggt gaaagcgccg atcacagcca
    21001 ttcgttgatg gctgcgacca gcaccgttgc ctcgtagcgc acggccaact tgtcgtacct
    21061 cgtggctacc gctcggtgcc gtttcagccg gttgatcccg cactccaccg cgtggcgctc
    21121 cttgtagtcg tccttgtcga aggccggcgg ccggccgcct cgggagccga gcttcttgcg
    21181 gttgcggacc tggttggctt tctccgggat ggtgcattcg atcctgcgtc tgcgcaggta
    21241 ggagcggttc gcgcgggatc cgtaggcctt gtccgcacgg actctgtcgg gcgtggtgcg
    21301 tggtgcgtgg tcgtccggga ccggtgcggg ggacgcggat acgttcgagg acgggccgga
    21361 agtgcgggct gtcgtgccgg tgcccggccg tgatcagcag cgacagcgac ttctgcccct
    21421 gctcggtcgc aaggtggatc ttcgtggtca gaccgctgcg ggagcgtccg agcccatggt
    21481 cgtccggctc ggtgtcgatc ccgccgggcg gctcgcgctg cagatccctt ttttacgcgc
    21541 gccggctgcg tgctggtggg cacggcacac ggtcgagtcc acactcacat cccagatgat
    21601 cagaccctgc gcgtcggcct ggacctgcag ttgttccaga ttccgcttcc aggtgccatc
    21661 gcgtcgcaac agaccctaat tggttccggc ggtgagttcg ctgaagagct tgtttgccgc
    21721 gtccgaggtg aactggcgct ggagctcggc gcgggcgacc tgcttgcgga attctccttc
    21781 gtagccggtg aagccggcgt tgtgcatggt gtcggtgatc caggtcgcga atgcctggat
    21841 cgagcgggac gacgacgagg cgcacgtcgg tcgggccgta gaagcggtgg gagtgggtga
    21901 aacgcggcgg cgtccaggtg acacggttgg ccggggcgac ccaggtcccg tgctccgtcg
    21961 ctgtggccag cgcgccggca gcggcgtaca caagctgccc tggacgtgcg aatgagggtc
    22021 gagccggtag ccgtgcggca gccacgcacc tccctgcaga atcgagttct ccgcttccgg
    22081 gggaatcgtc gaagaatggc ggctttccgg catcggtcat cagtttaccg gtggtgtggg
    22141 cggacgacgt cgagcgccgc tcgggcaccc cagcaccccg gcacccacgg ccgtcgaccc
    22201 ggaggcgctg ttcgccacct gcgggcgggg cgcattaggc cagtcggtgg aggtccgcgg
    22261 tcgctgtcgg gcaaatcgcg gtagttgtcc cgtcgggtcg ttggacgaga tccacgggcg
    22321 gcgcaggatg gtccggcgcg gggcggccca tgaacggcag gagaaatgcg atgtccatcg
    22381 atctgacgga gacgtcgatc accgaagcgg tgcagcggac tttcgacggc gcggaggacg
    22441 agcgggtcaa ggagctgttc atctgcctgg tgcagcatct gcacgacttc acgcgggagg
    22501 tgcggctgac cggtgccgag tggttcaagg tgatggattt ccttgagcgg gtgggcaaga
    22561 tctgcaatcc gactcggcag gagtacgtcc tgctgtccga cattctgggc ctgagtgtcc
    22621 tggtggacct gattcaccat ccgggaatcg ggtcggtgac ggattcgacg ctgctgggcc
    22681 ccttctacgt cgaaggccgg ccgacggcgg agaacgggtc ggacatctcc ggtggggtcg
    22741 cggggactcc gctgttcttc aacggccggg tgctcgaccc ggagggcaat gccgtggccg
    22801 gcgcccgggt ggacacctgg cacagcgacg gggagggctt ctacgacgtg cagatgccgg
    22861 agaggctgca cggccggttg gccatgcgcg ccttgctgac caccgacgac gaggggcggt
    22921 tctggtaccg gtcggtggcc ccccggtact acccggtccc gaccgacggg ccgtgcgggg
    22981 agatcctgcg tgccgcgaac cggtcgccga tgcgcccgga gcacctgcac ttctggttgc
    23041 acgccgaggg cttcgagcca ctgatcacca tgctggtccg cagggacgac ccctatgtgg
    23101 accgggacgc ggtcttcggg gtcaggcggt cgctggtggt ggacttcgtc cagcgcgacg
    23161 ccggggagac cgctccggac ggcacccgca tggacgagcc gttccagacg gtggagcgga
    23221 cgtttgtcct ggcccgtacg gagcgcgccc tgccccactg accagcacct ataagcacct
    23281 gtcagcacct gttgcaacgt gcggaaagga caacaagcat gcgcgcgcta cgcttcgagc
    23341 gattcggcgg ccccgaggtg ctgggcgtcg aggaggtcgc ggacccggtc gccggtgacg
    23401 gcgtggcggt cgttgccgtc aaggccgctt cgatcaaccc ctcggacgtg ctggccgtct
    23461 cgggccgcat ggaggacacc accctccccc gcactccggg ccgcgacttc gcgggcgtcg
    23521 tcctggaagg acccgacgac tgggtcggtg ccgaggtctg gggtaccggg ggagacatcg
    23581 gatacagcct cgacgggtcg cacgcggaac gtatcgccct gccggtcagc gcgctggccc
    23641 gcaaacccgt caccctggac ttcgccgagg cggcgacggt cggtgtgaac ttcgtggtcg
    23701 gctggctcgg tgctgtcgag accgccgaac tcgccgaggg cgagaccatc gccgtcttcg
    23761 gcgtctcagg aggcgtgggc ggagccgtcg cgcagatcgc ccgcgccgtc ggcgcccggc
    23821 gcattgtggg cgtcgccccg cacgccccgg cacccggtac ccctgcggcc gaggccatcg
    23881 acgcgtttgt gcccttcgac gccgacaccg acgtccccgc cgagatccgg cgactcaccg
    23941 gcggccgggg cgccgatgtc gtctacgacg ccgtaggcgg cgtcaccacg ccgtccgccg
    24001 tcgcgtccct tgcccaccgg ggccgcctgg tcgtcatcag cgccatcggc acctccaccg
    24061 ccgaggtcga cctccgcgac ttctaccacc gcgaactgcg catgctgggc gtcgacagcc
    24121 gcaaactgga cgtgaccgcc tctgccgaac gcctgaagcg gatcagcccc cacttcgagc
    24181 gcggtgagtt caggccgctc cccatcgtgc agaccttcga cctcgaccac ggcccggacg
    24241 cgtatcgcgc ggtggcggag aagacggtgc gcggccgggc cgtcatccaa ccctgagccg
    24301 ccgccgactg ctggagctgt gcagccagac gcggagcggg ccgagcacgg tgaagccgcc
    24361 ggccagtgcg ggggtgaggc cgtctccgcg ttcgtagccc acgaggggga ggccggggaa
    24421 gtggtcggcg gctgcggtga tcgctgagga ccagatggcg gcggtgccgc cggggtcggt
    24481 ggcgtacagg ttggagacgc cgaccggccc ggagccgcgg ttcaggacgg cgcccccggc
    24541 gaggtcgtcg ccgtcgagca cggccagcac cagcaccgac gggtcgtcca gcaacgccgg
    24601 tcggaagacg tccggggccc cggcgccgcc atgccaggcg tcctgccagt cgcggagccg
    24661 ggcggccgtg gcgacccgct cggtacgcag gcccggcgcc gccgccacgg ggagccctgc
    24721 gggacggtgg atccactggg cgtggaagag cacgccgaag ccgtacgagg tgaggtcgag
    24781 cgtggcgaag ctgtccttga cggagcaccc gggcgacgcc gtgtcgaccc ccggcaggaa
    24841 gtcgtccggc accgcgccct cgtgcagcgt gacggcgtcg gggtagtaga tcggcgtacg
    24901 ccgggaagcc caccaggccc cccggccaaa cgaggacccc gcagtgagcc agcaccgttc
    24961 cgcgccgcga ggctgggcgc ggcagccgcc agca
//
