LOCUS       NZ_CP031264            21884 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Peterkaempfera bronchialis strain DSM 106435 chromosome, complete
            genome.
ACCESSION   NZ_CP031264
VERSION     NZ_CP031264.1
KEYWORDS    RefSeq.
SOURCE      Peterkaempfera bronchialis
  ORGANISM  Peterkaempfera bronchialis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Peterkaempfera.
REFERENCE   1  (bases 1 to 7090212)
  AUTHORS   Nouioui,I., Klenk,H.P., Igual,J.M., Gulvik,C.A., Lasker,B.A. and
            McQuiston,J.R.
  TITLE     Streptacidiphilus bronchialis sp. nov., a ciprofloxacin-resistant
            bacterium from a human clinical specimen; reclassification of
            Streptomyces griseoplanus as Streptacidiphilus griseoplanus comb.
            nov. and emended description of the genus Streptacidiphilus
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 1047-1056 (2019)
   PUBMED   30741626
REFERENCE   2  (bases 1 to 7090212)
  AUTHORS   Batra,D. and Gulvik,C.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUL-2018) Bacterial Special Pathogens Branch, Centers
            for Disease Control, 1600 Clifton Road, Atlanta, GA 30329, USA
REFERENCE   3  (bases 1 to 7090212)
  AUTHORS   Gulvik,C.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAR-2018) Bacterial Special Pathogens Branch, Centers
            for Disease Control, 1600 Clifton Road, Atlanta, GA 30329, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: HGAP v. 3; Pilon v. 1.22
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 176.4x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003258605.2-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:52:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,114
            CDSs (total)                      :: 6,019
            Genes (coding)                    :: 5,833
            CDSs (with protein)               :: 5,833
            Genes (RNA)                       :: 95
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 186
            CDSs (without protein)            :: 186
            Pseudo Genes (ambiguous residues) :: 0 of 186
            Pseudo Genes (frameshifted)       :: 60 of 186
            Pseudo Genes (incomplete)         :: 147 of 186
            Pseudo Genes (internal stop)      :: 2 of 186
            Pseudo Genes (multiple problems)  :: 22 of 186
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:20:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3399918
            Orig. end                         :: 3421802
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031264.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21884
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="triceptide"
                     /product="phosphonate"
                     /region_number="11"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     triceptide_precursor) or triceptide_rSAM)"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..21884
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="neighbouring"
                     /product="triceptide"
                     /product="phosphonate"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..21884
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11884](-)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11884)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
     gene            338..580
                     /locus_tag="C7M71_RS15040"
                     /old_locus_tag="C7M71_015040"
     CDS             338..580
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437133.1"
                     /locus_tag="C7M71_RS15040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015040"
                     /product="DUF6458 family protein"
                     /protein_id="WP_111488654.1"
                     /transl_table=11
                     /translation="MGLGGCVILIALGAILTFATDWHVNGVNLDIVGVILIVVGLLGLI
                     TFSSVLRRPRRGFGPGIGADEVVEERHHYYDDPRL"
     misc_feature    complement(363..378)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.92"
                     /tool="antismash"
     gene            complement(767..2635)
                     /locus_tag="C7M71_RS15045"
                     /old_locus_tag="C7M71_015045"
     CDS             complement(767..2635)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006125907.1"
                     /locus_tag="C7M71_RS15045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015045"
                     /product="NHL domain-containing thioredoxin family protein"
                     /protein_id="WP_111488652.1"
                     /transl_table=11
                     /translation="MASRARVRAPELVGAGGWLNTGGKDLTLADLRGKIVIADFWTFCC
                     INCLHVLDELRELEERHRDTVVIVGVHSPKFVHEADHQAVVDAVARYEVHHPVLDDPEL
                     ATWKQYAVRAWPTLVVIDPEGYVVAQHAGEGHAHAIEKLVEELEAEHAAKGTLHRGDSP
                     YVPPEPEAGALAFPGKAVRLPDGGYLVADSGHHSLVELADDGETVRRRIGDGRRGLLDG
                     PADQARFSEPQGLALLPPDTAAALGCDLVVADTVNHALRGVRLADGEVTTLAGTGRQWW
                     QGSAVSGPAREVDLSSPWDVAWFADRVWIAMAGVHQLWAYDPATGTVEVAAGTTNEGLV
                     DGPAAEAWFAQPSGLAAAADGSRLWVADSETSALRWIDAADLTVHTAVGTGLFDFGHRD
                     GPADQALLQHPLGVTVLPDGSVAVSDTYNHALRRYAPPTGEVAAGEVTTLATDLREPSG
                     AVLVGDDIVVVESARHRLTRLRLPEEAVRVEGTAHRTQRPATEVAPGPFRIDVVFSAPA
                     GQKLDERYGPSTRLLVSATPPELLASGEGADSALSREVVLAADGPTEGVLHVSAMAASC
                     DDDPAVEYPACHVHQQDWGVPVRLVPGGAARLPLVLAGMDDPAADA"
     misc_feature    complement(2782..2793)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            2811..4184
                     /gene="gltX"
                     /locus_tag="C7M71_RS15050"
                     /old_locus_tag="C7M71_015050"
     CDS             2811..4184
                     /EC_number="6.1.1.17"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gltX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609487.1"
                     /locus_tag="C7M71_RS15050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015050"
                     /product="glutamate--tRNA ligase"
                     /protein_id="WP_229759126.1"
                     /transl_table=11
                     /translation="MFHVGGARSALYNWAVARQSGGTFVLRIEDTDAARNKPEWTDGII
                     SALAAIGIHGEDPAFEGPYFQSHNADRHREAAQQLFAAGRAYYCDCTREQLKERTGSEQ
                     LGYDGFCRDRGLAFEEGRALRFRTPDEGETVVVDLIRGEPAFPNSAIEDFVIARGDGSP
                     VFLIANVVDDLDEGITQVIRGEEHLSNTPKQQLLWEALGAKPPVWAHLPVIVNDKRQKL
                     SKRRDKVALEDYLAEGFLPEAMVNYLMLLGWGPGDDREIMPYEELERLFRIEDVNTAPA
                     FFDVKKLTAFNGEYIRALSPEQFAAACAPWLVAPYAPWAPEAFDKDVFEVAAPLAQTRL
                     ALLPEITGYVDFLFLYEPVEDEASWNKAMKAGAADILSNARAELAAVADWKADDLKAVL
                     LAIGEKHGLKLGKAQAPIRVAVTGRTIGLPLFESMELLGRNRVLARLDAAAKKLAAQA"
     gene            complement(4192..5178)
                     /locus_tag="C7M71_RS15055"
                     /old_locus_tag="C7M71_015055"
     CDS             complement(4192..5178)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004928407.1"
                     /locus_tag="C7M71_RS15055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015055"
                     /product="glycosyltransferase"
                     /protein_id="WP_111488650.1"
                     /transl_table=11
                     /translation="MKRVVYSMEPVGRTGGRVYLRMLHEVTADDVEWRTVPDHKRTYRV
                     RRWRKLRHLARLAPSIRALQGSTGTFVWDDLSLLLFTPEMRARTVFLLHHYEPLQHDSA
                     PVEAMLWERLFRVLPECAAVVCVAPYWADQLRARGVRSVRVIYNAFDMTEIEQARGYDR
                     AECRAEFGLTPDVIGVYAGKAVHWKGTEEVSAALSGAPGLRVITSGSNTIGLDSAHYDV
                     ERERYLRLLRACDVGVFLPRMREGWSRCAAEALLLGLPCLIRPVAGLGDLAALTGQPAP
                     DLRRLPAQVQERAAAGHTEAEAAYEALARFDLDHFGNAWGALLAKVA"
     gene            complement(5175..5789)
                     /locus_tag="C7M71_RS15060"
                     /old_locus_tag="C7M71_015060"
     CDS             complement(5175..5789)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007492084.1"
                     /locus_tag="C7M71_RS15060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015060"
                     /product="HD domain-containing protein"
                     /protein_id="WP_111488648.1"
                     /transl_table=11
                     /translation="MDLIDLDHVLTVLGAAAWSPDEQSRARVAAGLALTVYDGHTRDQG
                     TPYLEHPLAVVRLLRAEIGVRRPETLLLALLHDAVEVAPESGALLVHHLGGPFTARLRA
                     MTADHRLEQRTKSVGDETRWRTKQAALPPEDLLVRLADRLHNLRDLTASSNLDRRRRFL
                     RTLGDFHLPLADAARNLGPHLEAMHARLHAEYAHHIQEVRP"
     gene            complement(5795..7030)
                     /locus_tag="C7M71_RS15065"
                     /old_locus_tag="C7M71_015065"
     CDS             complement(5795..7030)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609484.1"
                     /locus_tag="C7M71_RS15065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015065"
                     /product="carbamoyltransferase C-terminal domain-containing
                     protein"
                     /protein_id="WP_229758738.1"
                     /transl_table=11
                     /translation="MDAVWAASMRPNPAAGWWLAEEREELAALLPAPLGERLRLLSHHT
                     AHVLSGYLLSGHERAGGLVIDAGGSSLGADFGPGRERITGYDLWPDRIDRLYQGMPAVV
                     PGPVGPRRVHSSPGHFYRNLARRVIPPGDEPEGSMMALAAFGDLHLNGRLAADSGFDTL
                     FVAPAPHDAGTAVGAALYGWHYQLGQERVPVPTDAAWGPGPGVLPTTTVPSGYRALSQL
                     GSGLAPTVAALLAEHRIVGWVQGQLEFGPRALGHRSILAHPGHTATRDRLNAIKKRAAY
                     RPFAPAVLTEHATEWFMSSGDPFMNRVATVRRCRADRIAAVTHHDGTARVQSVAADHQG
                     LRDLLEQFRDLTGLPLLLNTSLNRKGAPILRTAEQAVAAAVDLRLDALAVGDTLLLADH
                     VPGPRAASLRAR"
     gene            complement(7351..8229)
                     /locus_tag="C7M71_RS15070"
                     /old_locus_tag="C7M71_015070"
     CDS             complement(7351..8229)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.5"
                     /locus_tag="C7M71_RS15070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015070"
                     /product="phosphotransferase family protein"
                     /protein_id="WP_111488646.1"
                     /sec_met_domain="APH (E-value: 6.5e-11, bitscore: 41.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAYAWDDLPADLRASIQLRTGHVTKAVPPTAGTVSDYAATLDTAT
                     GPVFCKAIRTDNPRAWMHRREAAVSPALPNTAAALHWSVEAVGWLALGFEHIPGRHADL
                     SPGSGDLPLITRTLGQLADALTPAPPLRGFTLAERWSGQDYWQTVRERHPDRLGPWTAV
                     RLDALVTAEREAPGLVDGRTLAHTDLTGSNILISGGTARVIDWAFPAPGAPWVDTAYLV
                     VRLIGAGHTPAEAEQWAARLPLWREASPWAVTAFGATLAGLWTLRSAEQPGRQWDILSA
                     HGLAWLRHRLG"
     cand_cluster    7761..20056
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    7761..20056
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[12760:15056](-)"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(12761..15056)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="2"
     gene            complement(8297..8419)
                     /locus_tag="C7M71_RS32625"
     CDS             complement(8297..8419)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C7M71_RS32625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_265737658.1"
                     /transl_table=11
                     /translation="MDTELRGMPANCSEGSGGDGSDTSGSGNCSQCHQGCHNSN"
     gene            complement(8776..9684)
                     /locus_tag="C7M71_RS15075"
                     /old_locus_tag="C7M71_015075"
     CDS             complement(8776..9684)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04267.2"
                     /locus_tag="C7M71_RS15075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015075"
                     /product="aKG-HExxH-type peptide beta-hydroxylase"
                     /protein_id="WP_111488644.1"
                     /transl_table=11
                     /translation="MDLTTVFRMPAIHDLHRTKTERIHQALGRGAGRLITPTTHAPATG
                     YALAHHVLEGAEHAARVGDPDTFVWYSEHPDAAATELTPAAGPLTVVPAEEQLLTSYVS
                     DTPYYVLGPTTQAAPGHLHKLTLESATLAADQGFGDLVDAHAPIVCLLTGKPLGSPLRS
                     WTISRMPGTVFLDYVPDNTVMVARDLIHEAGHNWLNDALTATGCEIDNTRTFYSPWKKT
                     HRPAYGFIHGCWSFSLVTLYVAAVLPTTTGETHTFLTAYLDRQRAQLRVVTGDHETALR
                     TISDSTLRTRLRIVYRHALAF"
     gene            complement(9775..9915)
                     /locus_tag="C7M71_RS30675"
     CDS             complement(9775..9915)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C7M71_RS30675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162824256.1"
                     /transl_table=11
                     /translation="MKNDTWAKDFLDAVDELRDDDGSVRFTMHSSREGADDWPTEPTAH
                     A"
     gene            complement(10001..11884)
                     /locus_tag="C7M71_RS15080"
                     /old_locus_tag="C7M71_015080"
     CDS             complement(10001..11884)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_rSAM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311997.1"
                     /locus_tag="C7M71_RS15080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015080"
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_111488642.1"
                     /sec_met_domain="PTHR43273 (E-value: 2.4e-37, bitscore:
                     127.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.7e-08, bitscore:
                     33.2, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="triceptide_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPTTPNEQIDHLYRSLETSEADAVSVILKVRGETCDIDCLHCYE
                     KRKEGPGGARISADQVDLLPKLFGTRPLAIELHGGEPLTAGKDHIAHLLRTLAAMPQVK
                     RLSLQTNGVQLDAEWLDLFDTLYPGLEIGISLDGDPEGNRWRVDYQGKPTYPAAVRALD
                     LLAECGRTCGIITTVTPAVLGRHAEVLDHLAVFKAVTSVSFVPCFDATITRPTAYTGRR
                     RPASRALQQAVLTGLDGPAWAITPDQYAEFVLGVTQHWMTSGLFRRLKLSPAVPTIRRL
                     RGLGVSFCHFSDMKCDHVFTLYPDGRMGSCDELPWPQAQLTVLQPTTGRAEITAAQRNS
                     NLLGQGKDLMRACMTCDYRTTCGGGCIATRWRMNLTGQHDAYCDYRMRLIDGTAALLAD
                     PEHPGGAWCRTARWRPTPVNRMRDVQAFLTTWDNPTAPRRPAELHTSEFGNINTTGLPG
                     TQLADDLDPAHPQWAAAIEPGVKPLVDHLTSRWHLVTYDSCEGHQYDDPARNNQPRDVG
                     LLPRTPTEYAATAVALCRAANRCAAAMPAAVRLLVARNNLTCETTGRTYPVLDLRLLPT
                     SGTADSAYFAILDAATALLLGALEADAPNEGTCCACPLPADTHPELPQATA"
     gene            complement(11922..12764)
                     /locus_tag="C7M71_RS15085"
                     /old_locus_tag="C7M71_015085"
     CDS             complement(11922..12764)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C7M71_RS15085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C7M71_015085"
                     /product="hypothetical protein"
                     /protein_id="WP_111488640.1"
                     /transl_table=11
                     /translation="MNPWVEQRLKAARVVAKQLAREFPGSPVWMVGPVACGFAHARSDV
                     DLRVLFAEGPEPVLQSRIIDGIRVDLEALAATEADELRGYLRRFHILADDVDLFRTVRR
                     RLSALTVLRTARAMDGMEQPVLTATERDVYRRWALADRVQHAISLVEDLDGLFQANLNN
                     AMDLVVRQLHIAVQQAENVAGGHPLLGDKWTPVLAETPLPGVVPVHQAFSQARSRLLAA
                     LLTVWPDTAEPDGQVPDHWLDLGWIPQRYSDGWRLKFADLTIRLTPGRLAAWQKALRP"
     misc_feature    complement(12297..12299)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12761..13675)
                     /locus_tag="C7M71_RS15090"
                     /old_locus_tag="C7M71_015090"
     CDS             complement(12761..13675)
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072: dehydrogenase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012607.5"
                     /locus_tag="C7M71_RS15090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015090"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_162824257.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2.4e-13, bitscore:
                     48.2, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPTILVARGAANPNDLVRHLTTHDVYEFTCLSDVVGPARRAEL
                     IVLRSGISLGEEQLAAMPLLRHAIRAGSGLDGIDTDLLADRGIGLHRHPEASAPAVAEW
                     CLMALLALARRVPLGAHALGLGDHLKMACMGRPVASMNVAIWGAGPVGRAAAAAITPLV
                     AEVAFAARPSITGLRQLPAPALPGWADAHIIALPAIAENTATFGADFLRSAARRQPLLI
                     IAGRLTTIDTTACLGALADGRLSGLAADPVEPADAHLFTTGPKPLNLLATPHIGAQRSD
                     VREHLDIWVTETARRVLHGKGAA"
     gene            complement(13672..14145)
                     /locus_tag="C7M71_RS15095"
                     /old_locus_tag="C7M71_015095"
     CDS             complement(13672..14145)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311905.1"
                     /locus_tag="C7M71_RS15095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015095"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_111488636.1"
                     /transl_table=11
                     /translation="MSDLPSISVSVKAAIIHGGKVLLLSYDDSADGGCFHYNLPGGKAI
                     EGESLRDAVVRKVRQETGLAVRTVRSMFVMEYVPGQFGKNLGPQHKTQHNFLAEITDGR
                     TAPRFSDPRDPIQLGFEWVPLDQLTTKTLIPQVAPAILAALTDTRDALVDRAQ"
     gene            complement(14187..15056)
                     /locus_tag="C7M71_RS15100"
                     /old_locus_tag="C7M71_015100"
     CDS             complement(14187..15056)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311939.1"
                     /locus_tag="C7M71_RS15100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015100"
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_111488634.1"
                     /sec_met_domain="phosphonates (E-value: 1.3e-56, bitscore:
                     190.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 6e-45, bitscore:
                     152.1, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAVSPISPAGRLRAALGDATSSRLPVQAIGAVNAMAARVAAEA
                     GFDALWVSGLEVSAACGLPDENLLGSRDLADVVTSLRRVTDLPVIVDVDNAAGTGPSAA
                     RYGFDLLTAGAAAVCLEDSRYPKCNSFSEHRAQGLADTAAVCEQIKELRAAAPELLLIA
                     RTETLICGGSMDDALARAELYEAAGADAVLPHSKDISGREALEAARRWGGVPLVTVPTA
                     FPHLDRRLLGEAGFRLAIYANQLSRAALAAMRGAAGAFRATGAFRADQLAGVQDLMRVA
                     APDARACL"
     gene            complement(15053..15721)
                     /locus_tag="C7M71_RS15105"
                     /old_locus_tag="C7M71_015105"
     CDS             complement(15053..15721)
                     /EC_number="2.7.4.9"
                     /GO_function="GO:0004798 - thymidylate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0006235 - dTTP biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311999.1"
                     /locus_tag="C7M71_RS15105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015105"
                     /product="dTMP kinase"
                     /protein_id="WP_111488632.1"
                     /transl_table=11
                     /translation="MDTFPFVVIEGLDGSGKTTLRKGLFRLFDNLYGVTPLSVLTTNWL
                     DPEVAADLVDGKYAPTEANRDRYLAALRADKQATVERLIAPSLPLRPVIADRWLLSELA
                     FFQVKHGQAPADTYAELAGAIDLVPDLTLILEAATSTSMQRAASRGAGDAVRDDWDVVD
                     VQTSVRATYQAITGNPVAFPKIGPTVRIDAAQPRADVLADAWRALLERGLTPDPEGSIR
                     "
     gene            complement(15724..16458)
                     /locus_tag="C7M71_RS15110"
                     /old_locus_tag="C7M71_015110"
     CDS             complement(15724..16458)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C7M71_RS15110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C7M71_015110"
                     /product="hypothetical protein"
                     /protein_id="WP_111488630.1"
                     /transl_table=11
                     /translation="MEGTTPSVSPPGTLRPTTVRDSWQALADGLHVQRVHLHLEQWRKA
                     AALPAEQLRLPVELDPADMVSRPVLLVPHDDILIRAAGLRPWIEVPQRLGHDLTAAGPL
                     TLAVDEVARELAEGLDSGTEAAVHGAAGASAWWVGVFAVIHHESGRTASLAMLQAAARA
                     VALGTAMRVLRAALHAGGGGNPGLRAAYCRAVAETVVLEPSLPGLLGEIGGMRLTDLVT
                     TSVPWRGQFTKYQSGTGAGQVE"
     gene            complement(16578..16910)
                     /locus_tag="C7M71_RS15115"
                     /old_locus_tag="C7M71_015115"
     CDS             complement(16578..16910)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C7M71_RS15115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C7M71_015115"
                     /product="ATP-binding protein"
                     /protein_id="WP_111488628.1"
                     /transl_table=11
                     /translation="MARRLVREKLEEWGLDDMVDPAELIVSELVSNALKTGGLTFMQVA
                     IRRPARGYVRVFVRDGSRELPVLMEAGVDEECHRGLALVHHLTGGRWGAMLDPRGKSVH
                     ADLPVP"
     gene            complement(16997..17260)
                     /locus_tag="C7M71_RS15120"
                     /old_locus_tag="C7M71_015120"
     CDS             complement(16997..17260)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C7M71_RS15120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C7M71_015120"
                     /product="hypothetical protein"
                     /protein_id="WP_162824258.1"
                     /transl_table=11
                     /translation="MRRSSADQLRRRVPADATAGLPMQLASLDPDDRLIRICPAGAPGD
                     AWSKQSDGAEVFVNGFERALQRATVLRCLEGGRWRRQCRGLA"
     misc_feature    17500..17513
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.44"
                     /tool="antismash"
     gene            17530..18405
                     /locus_tag="C7M71_RS15125"
                     /old_locus_tag="C7M71_015125"
     CDS             17530..18405
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019982766.1"
                     /locus_tag="C7M71_RS15125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015125"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_175607689.1"
                     /transl_table=11
                     /translation="MAARPRPTARRIELGHELRQLRQQVGLTLEDAVKGLSFSETKLQR
                     VETGLQDLRNAGDLRKLLARYGVTDDDAVDQLVEIQRTASRQDWWMPYTMATMAPAMPR
                     FLGVESVAQAIRAYHPTCVLGLLQTERYALALHEIAKPIEETTTEFIQKSVALRMKRKE
                     RLVTPHDPVKLWAILYEPALRYVVGDPDLMREQYEEIVRLAKLDNVTVQILPQSVRGYL
                     SLSDFTYLDLGDTLPMTVQVDNAGAGMSITDKSREVGRFTRMFEALSRSALPSEATPEF
                     LQQLTREITS"
     gene            18402..18626
                     /locus_tag="C7M71_RS15130"
                     /old_locus_tag="C7M71_015130"
     CDS             18402..18626
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014144117.1"
                     /locus_tag="C7M71_RS15130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015130"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_111488622.1"
                     /transl_table=11
                     /translation="MTHHLPAAELADVAVWFKSSYSGSGNNCVDVADLTATSFEAMAIR
                     DSKDPDGPALLLAPEAFASLVAFAKKSTV"
     gene            complement(<18761..19144)
                     /locus_tag="C7M71_RS33215"
                     /old_locus_tag="C7M71_015135"
                     /pseudo=""
     CDS             complement(<18761..19144)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.5"
                     /locus_tag="C7M71_RS33215"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015135"
                     /product="phosphotransferase"
                     /pseudo=""
                     /sec_met_domain="APH (E-value: 1.9e-06, bitscore: 26.5,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPGLPQQQLTGTAHARLLRPRQGRHSSWPDLPADLRARLHPGGT
                     LGRPGRQSGKRRGLVDGRTLAHTDLTGSNILISGGTARVIDWAFPAPGAPWVDTAYLVV
                     RLIGAGHTPAEAEQWAARLPLWRE"
     gene            19352..19900
                     /locus_tag="C7M71_RS15140"
                     /old_locus_tag="C7M71_015140"
     CDS             19352..19900
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143777.1"
                     /locus_tag="C7M71_RS15140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015140"
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="WP_111488620.1"
                     /transl_table=11
                     /translation="MKYLVRERIFGIGDDFWVTTEGGEKAFLVDGKALRLRETFELRDA
                     SGRVVAVIRKKVLSVRDAMKVEDAHGETVATVKKKLFTPFRDSYRAELADGGELEIHGD
                     FLDKEYDIEGGGERLARISRKWFRIRDTYAVDVAEGADPALLLSVAVCVDRLAAEHEEE
                     QREKHGRHGEHGEHGERED"
     gene            complement(19971..21353)
                     /locus_tag="C7M71_RS15145"
                     /old_locus_tag="C7M71_015145"
     CDS             complement(19971..21353)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008734764.1"
                     /locus_tag="C7M71_RS15145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_015145"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_111488618.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.8e-10, bitscore:
                     39.0, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGHQPAHRAPRAVAALAAATAAVLTAAGTGDATVATAGGHPAGAG
                     TTAPHPASAGRALVHAVSKPISTTACLKKYNLRCYSPLQYRKAYNLNPLYRSGITGKGR
                     TIVIVDSFGSPTVQHDLDVFSKTFGLPSTTVQIVKWGKVPKFDPNIENHVGWAGETNLD
                     VQYAHAVAPDAKIVLVETAVAETEGLTGFPEMMDAENDLIKKGIGDVISMSFGATENTF
                     PGYAKGDHSALLNLRYAFKAAAARNVTLLAASGDSGATDYMLDGARLYKHRVVTWPSSD
                     PLVTSVGGTQLTLNNSGRRLKSDRVWNDGFGAAGGGVSGIFARPGFQRGVAAVVGNHRG
                     TPDVSLSAAVNGGAWVYSSFIPGQEGWGITGGTSEATPILAGIVALAAQKAHHRLGRIN
                     DDLYAMAKRFPRRNGLIDVVRGNNSFAGVKGYAAAKGYDLASGLGTIDATAFVRALARR
                     AR"
ORIGIN
        1 gctctccatg cactcctcgc gcgaactgtg cggcgccgac gacccgttcc tgctggcgtc
       61 cgcgctgaag gggttcctgg agggctgacc gggcgtctgc cgacgggcgg ggtgcgggcg
      121 ttggcccgca ccccgcccat cgcgtctcgc gccgtcgcgt gtcgcgccgt cgtgtcgcgc
      181 cgtcatgtcg cgccgtcgcg tcccgggccc ggggcggcat ggagcccccg ccgccgggta
      241 gccgcccacc aacggcccgc taccacaggg cagccccggc cgccgcccgg ccgacacgcc
      301 cggcggcgcc actcaacccc cttgggagga acccctcatg ggcctcggtg gatgcgtgat
      361 cctgatcgcc ctcggcgcca tcctcacctt tgcgaccgac tggcatgtca acggtgtcaa
      421 cctcgacatc gtcggcgtga tcctgatcgt ggtcggcctg ctcggcctga tcaccttcag
      481 cagcgtcctg cggcgccccc ggcggggctt cggcccgggg atcggggccg acgaggtcgt
      541 cgaggagcgc caccactact acgacgaccc ccggctctga gcctcggctc gtgctctcgg
      601 ccgcccggtc cggtacacaa cctcactggc cgggcgcggc gccccgagcc ggagcgtcag
      661 ggcgccgccc ggtccgccgc cgcccggtcc gctgccgccc ggtccgccgc cgcccgccca
      721 ggtcgcacgc aggcacgccg gtggtcggcc gggacggccg cgaccttcag gcgtccgccg
      781 ccgggtcgtc catacccgcg aggaccagcg gcaggcgggc ggcaccgccc gggaccagcc
      841 ggaccgggac gccccagtcc tgctggtgca catggcaggc ggggtactcg acggccgggt
      901 cgtcatcgca ggaggcggcc atggcggaga catgcagaac gccctcggtc gggccgtcgg
      961 ccgccagcac gacctcccgg gagagcgcgc tgtccgcgcc ctcaccggag gcgagcagct
     1021 ccggcggagt ggcgctgacc agcagccggg tggaggggcc gtagcgctcg tccagcttct
     1081 ggcccgccgg ggcggagaag accacatcga tccggaaggg gccgggtgcc acctcggtgg
     1141 cggggcgctg ggtgcggtgc gcggtgccct ccacccggac cgcctcctcg gggaggcgca
     1201 gccgggtgag ccggtgccgg gcggactcca ccaccacgat gtcgtcgccg acgagcaccg
     1261 cgccggaggg ttcgcgcagg tcggtggcga gggtggtgac ctctccggcg gcgacctccc
     1321 cggtcggcgg ggcgtagcgg cgcagtgcgt ggttgtaggt gtcgctgacc gcgaccgagc
     1381 cgtcggggag gacggtgacg cccagcgggt gctggagcag tgcctggtcg gcggggccgt
     1441 cgcggtggcc gaagtcgaag aggccggtgc cgacggcggt gtgcacggtg aggtcggcgg
     1501 cgtcgatcca gcgcagcgcg gaggtctcgg agtcggccac ccagagtcgg ctgccgtcgg
     1561 cggcggcggc gagcccggag ggctgggcga accacgcctc ggcggcgggg ccgtcgacca
     1621 ggccctcgtt ggtggtgccg gcggcgacct cgacggtgcc ggtggccggg tcgtacgccc
     1681 agagctggtg cactccggcc atggcgatcc agacgcggtc ggcgaaccag gcgacgtccc
     1741 acggggagga gaggtcgacc tcgcgggccg ggccggagac ggcggagccc tgccaccact
     1801 ggcggccggt gccggccagg gtggtcacct cgccgtcggc gaggcggacg ccgcgcagcg
     1861 cgtggttgac ggtgtcggcg acgaccaggt cgcagccgag tgcggcggcg gtgtccggcg
     1921 ggagcagcgc cagaccctgc ggttcgctga accgggcctg gtcggcgggg ccgtccagca
     1981 ggccgcgtcg gccgtcgccg atgcggcgcc gtacggtctc gccgtcgtcg gccagctcca
     2041 ccagggagtg gtgtccggag tcggcgacca ggtagccgcc gtccggcagc cgtacggcct
     2101 tgccggggaa ggcgagcgca ccggcctcgg gctccggcgg cacatagggg ctgtcgcccc
     2161 ggtgcagggt gcccttggcg gcgtgttcgg cctccaactc ctcgaccagc ttctcgatgg
     2221 cgtgggcgtg tccctcgccg gcgtgctggg cgacgacata gccctccggg tcgatcacca
     2281 ccagggtggg ccaggcgcgc accgcgtact gcttccaggt ggccagttcg gggtcgtcca
     2341 gcacggggtg gtgcacctcg tagcgggcga cggcgtcgac cacggcctgg tggtcggcct
     2401 cgtggacgaa cttgggcgag tgcacgccga cgatcaccac ggtgtcgcgg tggcgctcct
     2461 ccagttcccg cagttcatcg aggacatgca ggcagttgat gcagcagaac gtccagaagt
     2521 ccgcgatgac gatcttgccg cggaggtccg cgagggtgag gtccttgccg ccggtgttca
     2581 gccagccgcc tgcgccgacc agctcggggg cgcgtacacg tgcacgagaa gccatacccc
     2641 catcaaaccc caccggcccc gtccgcattc cgggacgggg gcggtggagg tgcggcaacg
     2701 tccgtaccgg ggtggggcga gtggtccggg ggctcaggcc cggcatcggt accctggagc
     2761 gcatgtctac tgccccggtt cgcgttcgtt tcgccccgtc cccgaccggc atgttccatg
     2821 tcggtggtgc acggtccgct ctctacaact gggcggtggc gcgacagtcc ggtggcacgt
     2881 tcgtcctgcg catcgaggac accgacgcgg cccggaacaa gcctgagtgg accgacggca
     2941 tcatcagcgc gcttgcggcg atcggtatcc acggcgagga cccggccttc gagggaccgt
     3001 acttccagtc gcacaacgcc gaccggcacc gggaagcggc gcagcagctc ttcgcggccg
     3061 gccgggcgta ctactgcgac tgcacccggg agcagctgaa ggagcgcacc gggtcggagc
     3121 agctcgggta cgacgggttc tgccgggacc gggggctggc cttcgaggag gggcgggcgc
     3181 tgcggttccg gacgccggac gagggcgaga ccgtcgtggt cgacctcatt cgcggggagc
     3241 cggcgttccc gaacagcgcg atcgaggact ttgtgatcgc ccggggggac gggtcgccgg
     3301 tctttctgat cgccaacgtg gtggatgacc tggatgaggg catcacgcag gtcatccgtg
     3361 gtgaggagca cctgtcgaac acgccgaagc agcagttgct gtgggaggcg ctcggagcca
     3421 agccgcccgt gtgggcgcat ctgccggtga ttgtgaatga caagcggcag aagctgtcca
     3481 agcgccgcga caaggtggcg ctggaggact acctcgccga gggcttcctg cccgaggcga
     3541 tggtgaacta cctgatgctc ctgggctggg gcccgggcga cgaccgggag atcatgccgt
     3601 acgaggaact ggagcggctc ttccggatcg aggacgtcaa cacggctccc gccttcttcg
     3661 acgtgaagaa gctgacggcg ttcaacggcg agtacatccg cgcgctctcg ccggagcagt
     3721 tcgccgccgc ctgcgcgccg tggctcgtcg ccccgtatgc gccgtgggcc ccggaggcgt
     3781 tcgacaagga cgtcttcgag gtggcggccc cgctggccca gacccgactg gcgctgctgc
     3841 cggagatcac cggctacgtg gacttcctgt tcctctacga gccggtcgag gacgaggcgt
     3901 cgtggaacaa ggcgatgaag gcaggcgccg ccgacatcct ctccaacgcc cgtgctgagc
     3961 tggccgccgt cgcggactgg aaggcggacg acctgaaggc cgtgcttctc gccatcggtg
     4021 agaagcacgg gctgaagctg ggcaaggccc aggcgcccat ccgggtcgcg gtcaccggcc
     4081 ggacaatcgg actccctctg ttcgagtcca tggaactgct cggccgcaac cgcgtgctgg
     4141 cccgcctgga cgcggcagcc aagaagctgg ccgcgcaggc gtagccgctg ctcaggcgac
     4201 cttcgcgaga agggcgcccc aggcgttgcc gaagtggtcc aggtcgaacc gggccagggc
     4261 ttcgtacgcc gcctcggcct cggtgtggcc tgccgccgcg cgttcctgga cctgtgccgg
     4321 aagacggcgg aggtccgggg ccggctgtcc ggtcagtgcg gcgaggtcac ccaggccggc
     4381 caccgggcgg atcaggcagg gtaggccgag cagcagggcc tcggccgcac agcggctcca
     4441 tccttcccgc atccggggga ggaagacgcc gacgtcacag gcgcgcagca gacgcagata
     4501 ccgctcccgc tcgacgtcgt agtgcgcact gtcgaggccg atggtgttgc tgccgctggt
     4561 gatcacccgc agcccggggg cgccggacag ggctgccgag acctcctcgg tccccttcca
     4621 gtgcacagcc ttgcccgcgt agacgccgat cacgtcagga gtcaggccga actcggcgcg
     4681 gcactcggcc cggtcgtagc cgcgtgcctg ctcgatctcg gtcatgtcga aggcgttgta
     4741 gatcacccgt acgctgcgaa cgccccgggc gcggagctgg tcggcccagt acggggcaac
     4801 gcacacgacg gcggcgcact ctggcagcac gcggaacagc cgctcccaga gcatggcctc
     4861 gacgggggcg gagtcatgtt ggagcggctc gtagtggtgc aggaggaaca ccgtgcgggc
     4921 gcgcatctcg ggcgtgaaca gcagcaggct caggtcgtcc catacgaacg tgccggtgct
     4981 gccctgcagg gcccgtatgg agggggccag gcgggcgagg tggcggagct tgcgccagcg
     5041 gcggactcgg taagtccgct tgtggtccgg gacggtgcgc cattccacgt cgtcggccgt
     5101 cacctcgtgg agcatccgta ggtagacccg gccgccggtc cggccgaccg gctccatcga
     5161 gtagacgacc cgtttcacgg acgtacctcc tgtatgtggt gggcgtactc ggcgtgcagt
     5221 cgcgcgtgca tggcttccag atgggggccg aggttgcggg cggcgtcggc gagggggagg
     5281 tggaaatcgc ccagggtccg gaggaaccgt cggcgccggt cgaggttcga ggacgcggtg
     5341 aggtcgcgca ggttgtgcag gcggtcggcg agccggacca ggaggtcctc gggcgggagc
     5401 gcggcctgct tcgtgcgcca gcgggtctcg tcgccgacgg acttcgtgcg ctgttcgagg
     5461 cggtggtcgg ccgtcatggc acgcaggcgg gcggtgaacg ggccgccgag gtggtggacg
     5521 agcagtgctc ccgactcggg cgctacctcc acggcgtcat ggaggagggc gaggaggagg
     5581 gtctcggggc gtcggacgcc gatctccgct cgcaagagcc ttacgacggc cagcgggtgc
     5641 tccaggtatg gggtgccctg gtcgcgggtg tggccgtcgt agaccgtgag agcgaggccg
     5701 gcggccacgc gggcgcggga ctgctcgtcc gggctccatg cggcggcacc gagcacggtc
     5761 aggacgtggt cgagatcgat gaggtccatc cgcctcacct cgcacgaagg gacgcggcac
     5821 gagggccggg gacgtggtcg gcgagcagca gggtgtctcc gacggcgagg gcgtcgaggc
     5881 gcaggtccac cgccgctgcc acggcttgct cggcggtccg caggatcggg gcgcctttgc
     5941 ggttgaggga tgtgttcagc agcagtggca gtccggtgag gtcgcggaac tgctcaagga
     6001 ggtctcgcag gccctggtgg tcggcggcga cggactggac gcgggcggtg ccgtcgtggt
     6061 gggtgaccgc cgcgatgcgg tcggctcggc accgccggac ggtggcgaca cggttcatga
     6121 aggggtcgcc cgacgacatg aaccactccg tggcgtgctc ggtgaggacg gccggtgcga
     6181 acgggcggta cgcggctcgc ttcttgatcg cgttgagtcg gtcccgcgtg gcggtgtgac
     6241 cggggtgggc gaggatcgag cgatggccga gggcacgcgg cccgaattcg agctgtccct
     6301 gcacccagcc gacgatgcga tgctcggcga gcagtgccgc cactgtgggg gccagtccgc
     6361 tcccgagctg ggacaaggcg cgatagccgg acggcaccgt tgtcgtcggc agcacgcccg
     6421 gaccggggcc ccaggcagcg tcggtcggca ccggtacgcg ctcctgcccg agttggtagt
     6481 gccagccgta gagcgcggcg cccacggctg taccggcgtc gtgcggggct ggcgcgacga
     6541 agagggtgtc gaatccgctg tcggcggcca gccgaccgtt gaggtggaga tcgccgaagg
     6601 ccgcgagcgc catcatgctg ccctcgggct cgtcgccggg tgggatcacc cgccgggcga
     6661 ggttccggta gaagtgcccg ggggaggagt ggacgcgccg gggccccacc gggcccggca
     6721 cgacggccgg catgccctgg tagaggcggt cgatgcgatc aggccacagg tcgtaccccg
     6781 tgatgcgctc ccggcccggg ccgaagtcgg cgcccagtga ggagccaccg gcgtcgatga
     6841 cgaggccccc ggcgcgctcg tgcccggaga gcaggtagcc ggagagcacg tgggccgtgt
     6901 ggtgggagag gaggcggagg cgttcgccga gcggggcggg caggagagcg gcgagttctt
     6961 cccgctcctc ggccagccac cagccggctg cggggttggg acgcatggag gcggcccata
     7021 cggcgtccac gtcctccggc tcgatgccgg ctgcctccag gcaccactgg agcgcgcggg
     7081 tcggagcggt gagcgtgccc ttgcgggtgc tggggtggtt gtgcttgtcg ccgctcgctg
     7141 ccgcggcctg tctcgaatgt tctcccgaga cggccgttgt ggtcccgctg gtccggtgac
     7201 tccggcgttc acctgccctg gcgtctcgac gcagcagtac gaggagacgt gaccgtgcaa
     7261 ctcctggccc agtcggttcg cggctatccg tcgctctccg agctgaccgc ctgatccggt
     7321 aggcgtcggg ccgccgggcg gtccgggcgg tcagccgagc cggtgccgca gccaggccag
     7381 tccgtgggcg ctgaggatgt cccactgccg accgggctgt tcggcgctcc ggagtgtcca
     7441 cagcccggcc agtgtcgcgc cgaaggccgt caccgcccac ggggatgcct cccgccagag
     7501 cggcagccgg gcggcccact gctcggcctc cgccggggtg tggcctgcgc cgatcagccg
     7561 gaccaccagg taggcggtgt cgacccaggg agcgccgggt gcggggaagg cccagtcgat
     7621 gacacgggcg gttccgcccg agatcaggat gttggagccg gtcaggtcgg tgtgcgcgag
     7681 cgttctgccg tcgaccaggc ccggcgcttc ccgctctgcc gtgaccagtg catcgaggcg
     7741 gactgccgtc cacggcccga gccggtccgg gtgccgctcg cgaactgtct gccagtagtc
     7801 ctggccggac cagcgttccg ccagggtgaa gccgcgcagg ggcggagcgg gggtcagagc
     7861 gtcggcgagt tgtccgagcg tgcgggtgat caggggcagg tcccccgacc ccggtgagag
     7921 gtcggcgtgg cggccgggga tgtgttcgaa cccgagcgcc agccagccga cggcctcgac
     7981 cgaccagtgc agcgcggcgg cggtgttcgg cagcgcaggg ctgacggctg cttcccggcg
     8041 atgcatccac gcccgggggt tgtccgtacg gatggccttg cagaacaccg gcccggtggc
     8101 ggtgtccagc gtggcggcgt agtccgagac ggtgcccgcc gtcggcggta cggccttggt
     8161 cacatggccg gtgcgcagtt ggatgctcgc gcggaggtcg gccggaaggt cgtcccaggc
     8221 gtaggccatg agttgcgccg tccttgagtc gggcccgccc gctccgagcc ggagggggcg
     8281 ggcgtgggcg gtggggtcag ttgctgttgt ggcagccctg gtgacactgc gagcagttgc
     8341 cgcttccact ggtgtcgctg ccgtcaccgc cgctgccttc ggagcagttg gcgggcatgc
     8401 cccgcagctc ggtgtccacg gtgtacccgc cggcttcgac agtccaaccc cagtgcctga
     8461 ccgagctgag caagcgcgtt cgacgcgttg tggcggcgct ggtcatcctc gcgtttgtag
     8521 ctcatgagct tcgttgctgc cctcggtgca agcaaggcac tcgttgatgc gacgcagggc
     8581 tcgctctgca tcgtgtcgcg tacctgcatt gttcgcaacg aaggcgcggc tgaccgcagt
     8641 ccggccggac cgcctgctta tgtgggcccc aaccggcgat tcgaggccca caggcgtatg
     8701 tgcagggtcg atgggcgccg aagcgaccgc tgtgcggctg ctttgcggca ggcgtccgag
     8761 gcaggagcga agccgtcaga acgcgagggc gtgccggtag acgatgcgca gccgggtacg
     8821 gagggtgctg tcgctgatgg tccgcagggc ggtttcgtgg tcgccggtga cgacgcggag
     8881 ctgggctcgc tgccggtcga ggtaggcggt gaggaaggta tgggtctcgc cggtggtggt
     8941 gggcagcacg gcggcgacgt agagcgtgac cagggagaac gaccagcagc cgtggatgaa
     9001 tccgtaggcg ggccggtgag tcttcttcca tggagagtag aaggtccggg tgttgtcgat
     9061 ctcgcagccg gtggcagtga gcgcgtcgtt gagccagttg tggccggctt catggatgag
     9121 gtcgcgggcg accatgacgg tgttgtcggg gacgtagtcg aggaagacgg tgccgggcat
     9181 gcggctgatg gtccagctgc gcagggggct gccgaggggt ttgccggtga gcaggcagac
     9241 gatcggggcg tgggcgtcta ccaggtcgcc gaaaccttgg tcggcggcga gggtggccga
     9301 ttccagggtg agcttgtgca ggtgcccggg ggcggcctgg gtggtggggc cgaggacgta
     9361 gtacggggtg tcggagacgt acgaggtgag cagttgctcc tccgccggca cgacggtgag
     9421 cggcccggcg gccggagtga gctcggtagc tgcggcgtcg gggtgctcgc tgtaccagac
     9481 gaaggtgtcg gggtcgccca cgcgagcggc gtgttcggcg ccttcgagga cgtggtgcgc
     9541 gagtgcgtag ccggtggcgg gggcgtgcgt ggtcggggtg atgaggcggc cggcgccccg
     9601 gccgagggcc tggtggatgc gctcggtctt ggtccggtgg aggtcgtgga tcgcgggcat
     9661 gcggaagacg gtggtgaggt ccatcgcggt ctccttgcgg gggctgggtg gggccaggac
     9721 ctgggtggcc ctggccccgg ggtgtctagc gagccaggca cccaggtgtt ccggtcatgc
     9781 gtgggcggtc ggctcggtcg gccagtcgtc ggcgccctcc cgggaggagt gcatggtgaa
     9841 gcggacggac ccgtcgtcgt cccggagctc gtcgacggcg tcgaggaagt ccttggccca
     9901 ggtgtcgttc ttcacagcgg atgccctttc tgtgcaggtc ggctggggtg tgatggagtt
     9961 ctgcgggtcg gcggtgatcg ctcccgtggt gtcgcggtgt tcacgccgtg gcctgtggaa
    10021 gttcggggtg ggtgtcggcc gggagtgggc aggcacagca agtgccctcg ttgggggcgt
    10081 cggcttcgag ggcgcccagg agcaacgcgg tggcggcgtc caggatggcg aagtacgcgc
    10141 tgtccgccgt tccggaggtg gggagcaggc gcaggtcgag gaccgggtag gtacgaccgg
    10201 tggtctcgca ggtcaggttg ttccgggcga ccaggaggcg gacggccgcc ggcatggcgg
    10261 cggcgcagcg gttggcggca cggcacaggg cgactgcggt ggcggcgtac tcggtggggg
    10321 tgcgggggag gaggccgacg tcccgcggct ggttgtttcg ggcggggtcg tcgtactggt
    10381 ggccttcaca gctgtcgtac gtaacgaggt gccagcggct ggtgaggtgg tcgacgagcg
    10441 gtttgacgcc gggctcgatc gcggcggccc actgagggtg ggcggggtcg aggtcgtcgg
    10501 cgagctgggt gccgggcagg ccggtggtgt tgatgttgcc gaactcgctg gtgtgcagct
    10561 cggccgggcg gcggggggcc gtggggttgt cccaggtggt gaggaacgcc tggacgtcgc
    10621 gcatccggtt gacgggggtg gggcgccagc gggcggttcg gcaccaggcg ccgcctgggt
    10681 gttcggggtc ggcgaggagc gctgcggtgc cgtcgatcag ccgcatccgg tagtcgcagt
    10741 acgcgtcgtg ctggccggtg aggttcatgc gccagcgggt ggcgatgcag ccgccgccgc
    10801 aggtggtgcg gtagtcgcag gtcatgcacg cccgcatgag gtccttgccc tggccgagga
    10861 ggttggagtt gcgctgtgcg gcggtgatct cggcccggcc tgtggtgggc tgtaggacgg
    10921 tgagttgggc ctggggccag gggagttcat cgcagctgcc catgcgtccg tcggggtaga
    10981 gggtgaacac gtggtcgcac ttcatgtccg agaagtggca gaacgacacc ccgaggccgc
    11041 gcagccgacg gatggtgggc acagccgggg agagcttgag gcggcggaac agcccgctgg
    11101 tcatccagtg ctgggtgacg ccgagcacga actctgcgta ctggtcgggg gtgatcgccc
    11161 acgccgggcc gtcgaggccg gtgaggacgg cttgctggag ggcacggctg gccggacggc
    11221 ggcgaccggt gtacgcggtg ggccgggtga tggtggcgtc gaagcacggt acgaagctga
    11281 cggaggtgac ggccttgaac acggccaggt ggtccaggac ctcggcgtgg cgcccgagga
    11341 ccgcaggggt gacggtggtg atgatcccgc acgttcggcc gcactcagcc aggaggtcca
    11401 gtgccctgac ggcagcgggg taggtgggtt tgccctggta gtcgacgcgc caccggttcc
    11461 cctcggggtc gccatccagg gagatgccga tctccagacc ggggtacagg gtgtcgaaca
    11521 ggtcgagcca ctcggcatcg agctggacgc cgttggtctg tagggacagg cgcttgacct
    11581 gcggcatggc cgcgagggtg cgcagcaggt gggcaatgtg gtccttaccg gcggtgagcg
    11641 gttcgccgcc gtggagttcg atggcgagcg gccgggtgcc gaagagcttc gggaggaggt
    11701 cgacctggtc ggcgctgatc cgcgcgccac cgggtccctc cttgcgcttc tcgtagcagt
    11761 gcaggcagtc gatgtcgcag gtctcgccgc ggaccttgag gatcaccgag acggcgtcgg
    11821 cctcggatgt ctccagcgac cggtacaggt ggtcgatctg ctcgttcgga gtggtggggt
    11881 gcatctggtg cctcccaagg aggagcgggc tccgggcccg gtcaagggcg aagcgccttc
    11941 tgccacgcgg ccagccggcc gggggtgagg cggatggtga ggtcggcgaa cttcagtcgc
    12001 cagccgtcgc tgtagcgctg ggggatccat ccgaggtcca accagtggtc cggcacctgg
    12061 ccgtccggct cggcagtatc cggccacacg gtcagcagcg cggccagcag ccggctgcgg
    12121 gcctgactga atgcctggtg aaccgggacc acgcccggca gcggggtctc ggcaaggacg
    12181 ggggtccact tgtcgccgag cagcggatgg ccgccagcca cgttctctgc ctgttggacg
    12241 gcaatgtgca gctgccgcac caccaggtcc atggcgttgt tcaggttggc ctggaataag
    12301 ccgtccagat cctcgaccag actgatcgcg tgctggaccc ggtctgccag cgcccacctg
    12361 cggtagacat cccgctcagt ggcggtgaga accggctgct ccatgccgtc catggcacgg
    12421 gcggtacgca gcacggtcag cgcggacaag cggcgtcgga cggtacggaa caggtcgacg
    12481 tcgtcggcga ggatatggaa tcgccgcagg tagccccgca gttcgtcggc ctcggtggcg
    12541 gccagggcct ccagatcgac ccggatgccg tcgataatgc gggactgaag caccggctcc
    12601 gggccttcgg cgaacagcac ccgcaggtcg acatcactgc gggcatgggc gaatccgcag
    12661 gcgacgggcc ccaccatcca caccggcgag cccggaaact ccctggccag ctgcttggcg
    12721 accacacggg ctgccttcag cctctgctcc acccacgggt tcacgccgct cccttgccgt
    12781 gcaggaccct gcgagcggtc tcggtgaccc agatgtccag gtgctcgcgg acgtcgcttc
    12841 gctgtgctcc gatgtgcggg gtggcgagca ggttcagcgg cttcgggcca gtggtgaaca
    12901 gatgcgcgtc ggcgggttcg accgggtcgg cggcgagacc ggacaggcgg ccgtcggcga
    12961 gggcgccaag gcatgccgtg gtgtcgatgg tggtcaggcg tccggcgatg atcagcagcg
    13021 gctggcgcct tgctgccgag cggaggaagt cggccccgaa cgtggcggtg ttctccgcga
    13081 tagcgggcaa tgcgatgata tgggcgtctg cccagccggg cagcgcgggc gcgggcagct
    13141 ggcgcagccc ggtgatgctc ggccgggcgg cgaaggcgac ctcggcaacc aacggcgtga
    13201 tggcggcagc ggctgcccgg ccgaccggtc cggcacccca gatggccacg ttcatcgacg
    13261 cgaccggacg acccatgcag gccatcttga ggtggtcgcc caggcccaga gcgtgcgcgc
    13321 cgagcgggac gcgccgagcc agggcgagca gcgccatcag gcaccactcg gcgaccgccg
    13381 gagcggatgc ctccgggtgg cggtgcaggc cgatcccccg atcggcgagg aggtcggtgt
    13441 cgatgccgtc cagcccggag ccggcccgga tggcgtggcg cagcaatggc atggcggcca
    13501 gctgttcctc accgagagag atgccggagc ggaggacgat cagctccgcg cggcgcgcgg
    13561 gcccgacaac gtcgctgagg caggtgaact cgtagacgtc gtgtgtggtc aggtgtcgga
    13621 cgaggtcgtt cgggttggcc gcaccgcgag cgacgaggat cgtgggggcg ctcattgggc
    13681 acggtccacg agggcatcgc gggtgtccgt gagggcggcg aggatggcgg gggcgacctg
    13741 ggggatgagg gtcttggtgg tgagctggtc cagcggcacc cattcgaagc cgagttggat
    13801 ggggtcgcgc gggtcggaga acctgggtgc ggtgcggcca tcggtgatct cggcgaggaa
    13861 gttgtgctgg gtcttgtgct gcggcccgag gttcttgccg aactggccgg gcacgtactc
    13921 catgacgaac atcgaccgca cggtccgcac cgcaaggccg gtctcctgcc gaaccttgcg
    13981 gacgacggcg tcgcgcagcg actctccctc gatcgcctta cctccgggta ggttgtagtg
    14041 gaaacagccg ccgtcggcgc tgtcgtcgta ggacaggagc aggaccttcc cgccgtggat
    14101 gatcgctgcc ttcaccgaca cgctgatgct gggcagatcg ctcaaggtat gtgtctccgt
    14161 actgggctgt cggggcggaa gggatgtcac aggcaggcgc gggcgtcggg ggcggcgacg
    14221 cgcatcaggt cctggacgcc ggccaactgg tcggctcgga aggcacccgt ggcgcgaaag
    14281 gcaccggccg caccccgcat cgcggccagt gcggcgcggg acagctggtt cgcgtagatc
    14341 gccaggcgga acccggcctc cccgaggagt cgccggtcaa ggtgggggaa cgcggtggga
    14401 acggtgacca gcggcacgcc gccccaccgg cgggcggcct ccagagcctc acggccgctg
    14461 atgtccttgc tgtgcggcaa cacggcgtcc gccccggctg cctcgtacaa ctctgcccgg
    14521 gccagcgcgt cgtccatgct gccgccgcag atcagcgtct cggtgcgggc gatcagcagc
    14581 agctccgggg cggcggcccg cagctctttg atctgctcgc acaccgctgc ggtgtccgcc
    14641 aacccctggg cgcgatgctc ggagaacgag ttgcacttgg gatagcggct gtcctccagg
    14701 cagacggctg ccgccccggc cgtcaggagg tcgaacccgt acctcgcggc cgacggcccg
    14761 gtgccggcgg cgttgtccac gtccacgatc accggcaggt cggtgacacg gcgcagcgag
    14821 gtgacgacat ccgccaggtc ccgggagccg agcaggttct cgtccgggag cccgcaggcg
    14881 gccgacacct ccaggcccga cacccacagc gcatcgaatc cggcctcggc ggcgacccgg
    14941 gccgccatgg cgttcaccgc cccgatcgcc tgaacgggaa gccgggagct ggtggcgtcg
    15001 ccgagggccg cgcgtaggcg cccggccgga gatatcgggg atacggccgt agtcatcgga
    15061 tgctcccttc cggatcgggg gtgaggccgc gttccagcag tgccctccag gcgtccgcaa
    15121 gtacgtcggc cctgggctgc gcggcatcga tgcgcacggt cgggccgatc ttcgggaacg
    15181 cgaccggatt gccggtgatc gcctggtagg tggcgcgcac gctggtctgc acgtccacca
    15241 cgtcccagtc gtctctgacc gcgtcccctg ctcctcggga ggcggcgcgc tgcatggagg
    15301 tgctggtggc cgcctccaga atgagcgtca ggtcggggac caggtcgatc gccccggcca
    15361 gttcggcata ggtgtccgcc ggggcctggc catgcttgac ctggaagaac gcgagttccg
    15421 acagcagcca tcggtccgcg atcaccgggc gaagcggcag cgacggcgcg atcaggcgct
    15481 cgacggtggc ctgcttgtcg gcgcgcagag ccgcgaggta gcggtcccgg ttggcctcgg
    15541 tgggcgcgta cttgccgtcc accaggtctg cggccacctc gggatcgagc cagttcgtgg
    15601 tgagcaccga cagcggcgtc accccgtaca ggttgtcgaa gagccggaac agccccttgc
    15661 gcagcgtcgt cttgccactg ccgtccaggc cctcgatcac gacgaacgga aatgtgtcca
    15721 tccctactcc acctgccccg ctccggtgcc cgactggtac ttggtgaact ggcctcgcca
    15781 tggcaccgag gtggtgacca ggtcggtgag ccgcatccca ccgatctcgc cgagcagccc
    15841 cgggagtgac ggctccagca ccaccgtttc ggcgacggcc cggcagtagg cggcgcgcag
    15901 ccccgggttg ccccctcccc cggcgtgcag ggccgcgcgc aggactcgca tcgccgtacc
    15961 gagggcaaca gcgcgggcgg cagcctggag catcgccagg gaggcggtgc gaccgctctc
    16021 gtggtggatg acggcgaaca ctccgaccca ccaggcactg gccccggccg cgccgtgcac
    16081 ggcggcttcg gtgccgctgt cgagcccctc ggccaactcc cgggccacct cgtccaccgc
    16141 gagggtgagc ggcccggcgg cggtcaggtc gtggccgagc cgctgcggca cctcgatcca
    16201 cggccgcaga ccggcggcgc ggatcaggat gtcgtcgtgc ggcacgagga ggaccggccg
    16261 ggacaccatg tcggcggggt ccaactcgac gggcagcctg agttgttcgg ccgggagcgc
    16321 tgcggccttc cgccactgct ccaggtgcag gtgcacccgc tgcacatgca ggccgtcggc
    16381 gagggcctgc cagctgtccc gtacggtggt cggccggagt gttccgggtg ggctcacgct
    16441 gggggtggtt ccttccatgc agtactcctt gggtgggcgc gtcgaagcga tgaatcgtag
    16501 tcatacagtg acggagagcg acgacatgtg ccgtcggcgg ccggtcggtg gatcgagttg
    16561 atcgggcgct gtgtgggtca ggggacggga aggtcggcgt gcacggactt gccccggggg
    16621 tcgagcatgg cgccccaccg gccgccggtg aggtggtgga ccagggcgag cccgcggtga
    16681 cactcctcgt ccactccggc ctccatcagc accggcagtt cacgggaacc gtctcgcacg
    16741 aagacgcgga cgtatcccct ggcaggacgc cggatggcca cctgcatgaa cgtcaggccg
    16801 ccggtcttga gggcgttgga caccagctcc gagacaatga gctcagcggg gtcgaccatg
    16861 tcgtccaggc cccactcctc aagcttctcc cgaacaagtc ggcgggccat ccgtgccgac
    16921 tccgggcggt acggaagaga tgccgtcgcg gggcgcggcg gacagacccg agcggcgagg
    16981 gcgatctcgg tcgctgtcac gccagccccc ggcactgcct gcgccaccgg ccgccctcca
    17041 ggcaccgcag gaccgtggca cgctgcaagg cccgctcgaa gccattcacg aagacctcgg
    17101 cgccgtccga ctgcttgctc caagcatccc caggcgcacc ggcggggcat atccggatca
    17161 ggcggtcgtc cgggtccagc gaggccagct gcatggggag tccggcagtg gcatcggccg
    17221 gcacccggcg gcgcagctgg tctgcagagg atcggcgcac ggagacctcc ggagtccgat
    17281 ggtggaggcg gcggtccccc ggcatcgagg gacgcatcaa aggccgcagc tgatgcccca
    17341 tcaatcgggg cgctccaaca ccgtggcgct ttttcgctga atctgcaacg gaatcggcac
    17401 tgaatcaccc acggaaggag aagtggcaca tgccgccgca agcgcatggc ctggcactgc
    17461 cagcatgtga cgtgcgacac tgcgcgaatc ggtacggatg gtaagcgcat gcactcggga
    17521 ggtaagcacg tggcagcacg gccaaggccg acggcgcggc ggatcgagct ggggcacgag
    17581 cttcggcagc tgcgtcagca ggtcggcctc actctcgaag acgccgtcaa ggggctgtcg
    17641 ttcagcgaga cgaaactcca gcgggtcgaa accggcttgc aggacctccg caatgccgga
    17701 gacctgcgga agctcctcgc caggtacggc gtcaccgatg acgacgcggt tgatcagctg
    17761 gtagagatcc agcggaccgc ctcgcgccag gactggtgga tgccgtacac catggcgacg
    17821 atggctcccg cgatgccgcg cttcctcggc gtcgagtccg tggctcaggc catccgggca
    17881 taccacccga cttgcgtgct cggcttgctg caaaccgaac ggtacgcact ggccctacat
    17941 gagatcgcca agccgatcga agagaccacc accgagttca tccagaagag cgtggcgctg
    18001 cgcatgaagc gcaaagagcg cctggtgacc cctcatgatc ccgtcaagtt gtgggcgatc
    18061 ctgtatgagc cggcgctccg atacgtggtc ggcgacccag acctcatgcg cgagcagtac
    18121 gaggagatcg tccggcttgc gaagctcgac aacgtgaccg tgcagatcct gccccagtcc
    18181 gttcgcggct acctgtcgct ctccgatttc acctacctgg acctcggcga cacactgccc
    18241 atgacagtcc aggtagacaa tgctggggcc ggtatgtcca tcacggacaa gtcccgcgag
    18301 gtcggccggt tcactcggat gttcgaggca ctgtcccgct cggctctccc gtccgaggcg
    18361 acaccggagt tcctacaaca actcacccga gagatcacct catgacccat cacctccctg
    18421 ccgccgaact cgccgatgta gccgtctggt tcaagtcgtc gtacagcggc tccggcaaca
    18481 actgcgtcga tgtcgccgac ctgaccgcca cctcctttga ggccatggcc atccgcgact
    18541 cgaaggaccc cgacggtccg gccttgctcc tcgcccctga ggcgttcgcc agtctcgtgg
    18601 cattcgccaa gaagtccacc gtttgatcag caaagggccg ctctccctcg tccgaagcag
    18661 ggggaggcgg cccttccgct gtactggtgt cccatgccct ccggagtgtc cacagcccgg
    18721 ccagtgtcgc gccgaaggcc gtcaccgccc acggggatgc ctcccgccag agcggcagcc
    18781 gggcggccca ctgctcggcc tccgccgggg tgtggcctgc gccgatcagc cggaccacca
    18841 ggtaggcggt gtcgacccag ggagcgccgg gtgcgggaaa ggcccagtcg atgacacggg
    18901 cggttccgcc cgagatcagg atgttggagc cggtcaggtc ggtgtgcgcg agcgtcctgc
    18961 cgtcgaccag gccacggcgc ttcccgctct gccgtcctgg ccgccccagc gttccgccag
    19021 ggtgaagccg cgcgcggagg tcggccggga ggtcaggcca tgagctgtgc cgtccttgtc
    19081 tgggccggag gaggcgggcg tgggcggtgc cggtcagttg ctgttgtggc agccctggtg
    19141 acactgcgag cagttgccgc tttcactggt tggcggcgac agtcacgcca tgggtcgagc
    19201 cgacggctca ggacggctac tcgacctgat cggtacagcg tgccgccgga ggcgtgaggg
    19261 gtgccgtccg ggcgggggtg gcgaaccggg gggtggcggg gaggcgtcca aggtggtggg
    19321 agctgttcgg gacggcggag ggaagtgtgg gatgaagtac ctggtgcggg agcggatctt
    19381 cgggatcggt gatgacttct gggtcacgac cgaggggggc gagaaggcgt tcctggtgga
    19441 tgggaaggcg ctgcggctgc gggagacgtt cgagctgcgg gatgcctccg ggcgggtggt
    19501 cgcggtgatc cggaagaagg tgctgagtgt gcgcgacgcg atgaaggtcg aggacgcgca
    19561 cggggagacc gtggcgacgg tgaagaagaa gctcttcacg ccgttccgcg actcctatcg
    19621 ggcggagctg gcggacggcg gtgagctgga gatccacggc gacttcctcg acaaggagta
    19681 cgacatcgag gggggcggcg agcggctggc gcggatctcg cggaagtggt tccggatccg
    19741 ggacacctat gcggtggatg tggccgaggg ggcggacccg gcgctgctgc tgtcggtggc
    19801 ggtctgtgtg gaccggctgg cggcggagca cgaggaggag cagcgggaga agcacgggag
    19861 gcatggcgag cacggggagc acggggagcg ggaggactga ccgccggcgt ggcctcgggc
    19921 cctcccggtg gagggcccga ggccacgggc gggacgggcg gcggcgccgg tcagcgggcg
    19981 cgtctggcga gggcgcggac gaaggcggtg gcgtcgatgg tgccgaggcc gctggcgagg
    20041 tcgtagccct tggcggcggc gtagcccttg actccggcga aggagttgtt gccgcgcacc
    20101 acgtcgatca ggccgttgcg gcgcgggaag cgcttggcca tggcgtagag gtcgtcgttg
    20161 atccggccga ggcggtggtg ggccttctgg gcggcgaggg cgacgatccc ggcgaggatc
    20221 ggggtggcct cgctggtgcc gccggtgatg ccccagccct cctggccggg gatgaacgag
    20281 gagtagaccc aggcgccgcc gttgacggcg gcgctcaggc tgacgtcggg ggtgccccgg
    20341 tggttgccga ccacggcggc gaccccgcgc tggaagccgg ggcgggcgaa gatgccggag
    20401 acgccgccgc cggcggcgcc gaagccgtcg ttccagaccc ggtcggactt cagccgcctg
    20461 ccggagttgt tgagggtgag ctgggtgccg ccgacggagg tgaccagcgg gtcggaggac
    20521 ggccaggtga ccacccggtg cttgtagagg cgggcgccgt ccagcatgta gtcggtggcg
    20581 ccggagtcgc cggaggcggc gagcagggtg acgttcctgg cggcggcggc cttgaaggcg
    20641 tagcggaggt tcagcagcgc ggagtggtcg cccttggcgt agccggggaa ggtgttctcg
    20701 gtggcgccga agctcatcga gatgacgtcg ccgatgccct tcttgatgag gtcgttctcg
    20761 gcgtccatca tctcggggaa gccggtcagg ccctcggtct cggcgacagc ggtctccacc
    20821 agcacgatct tggcgtcggg ggccacggcg tgggcgtact gcacatcgag gttggtctcg
    20881 ccggcccagc cgacgtggtt ctcgatgttg gggtcgaact tcggcacctt gccccacttg
    20941 acgatctgca ccgtggtgct gggcaggccg aaggtcttgg agaagacgtc caggtcgtgc
    21001 tggacggtgg gggagccgaa ggagtccacg atgacgatgg tccggccctt gccggtgatg
    21061 ccggagcggt agagcgggtt gaggttgtac gccttgcggt actggagcgg cgaatagcac
    21121 cggaggttgt acttcttcag acacgcggtc gtggagatcg gcttgctcac cgcatggacc
    21181 agcgcgcgcc cggcggaggc ggggtgcggc gcggtggtcc cggcacctgc cgggtggccg
    21241 ccggcggtcg cgacggtggc atcgccggtt ccggcggcgg tgaggacggc ggcggtggcc
    21301 gcggcgaggg cggcgaccgc cctgggggcg cggtgagcag gctggtggcc catggtgctc
    21361 ctttggcggg gacgccatag gcgtccttgt ctgctggtcc ggggagagca gatccgatcg
    21421 gagggcgtcg acccatggtg ttgacggtct ctttgacctc gcaagtcgag tgatcacgcg
    21481 ctgtgcgtgt acggtcaccg gaaatgccga cccggagggg accgctgacc aggcgtccgg
    21541 gctgcgagga gagtgctgcg ccggggaccg tacgggtgat cggccgcgca tgggcgaggc
    21601 cccggcggcg gctgccgtcg gggcctcggg cggacaaaca gcgaaggaac ggcggcgtca
    21661 gcgccgtacg ggagcgggga tgccgagcag gcggtcgcgg agcaccggga agtcggcgcg
    21721 tgccttggcg acggccgccg ggtcgatctc cacggtgagg acctcctcgc cggtcccggc
    21781 ttcggccacc acctcgcccc aggggtcgac caccaggctg cggccggcct gctcaacccc
    21841 gccgtgggtg cccgccgtgt tgcaggccag cacatacgcc tgct
//
