LOCUS       NZ_CP031264            21131 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Peterkaempfera bronchialis strain DSM 106435 chromosome, complete
            genome.
ACCESSION   NZ_CP031264
VERSION     NZ_CP031264.1
KEYWORDS    RefSeq.
SOURCE      Peterkaempfera bronchialis
  ORGANISM  Peterkaempfera bronchialis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Peterkaempfera.
REFERENCE   1  (bases 1 to 7090212)
  AUTHORS   Nouioui,I., Klenk,H.P., Igual,J.M., Gulvik,C.A., Lasker,B.A. and
            McQuiston,J.R.
  TITLE     Streptacidiphilus bronchialis sp. nov., a ciprofloxacin-resistant
            bacterium from a human clinical specimen; reclassification of
            Streptomyces griseoplanus as Streptacidiphilus griseoplanus comb.
            nov. and emended description of the genus Streptacidiphilus
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 1047-1056 (2019)
   PUBMED   30741626
REFERENCE   2  (bases 1 to 7090212)
  AUTHORS   Batra,D. and Gulvik,C.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUL-2018) Bacterial Special Pathogens Branch, Centers
            for Disease Control, 1600 Clifton Road, Atlanta, GA 30329, USA
REFERENCE   3  (bases 1 to 7090212)
  AUTHORS   Gulvik,C.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAR-2018) Bacterial Special Pathogens Branch, Centers
            for Disease Control, 1600 Clifton Road, Atlanta, GA 30329, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: HGAP v. 3; Pilon v. 1.22
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 176.4x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003258605.2-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:52:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,114
            CDSs (total)                      :: 6,019
            Genes (coding)                    :: 5,833
            CDSs (with protein)               :: 5,833
            Genes (RNA)                       :: 95
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 186
            CDSs (without protein)            :: 186
            Pseudo Genes (ambiguous residues) :: 0 of 186
            Pseudo Genes (frameshifted)       :: 60 of 186
            Pseudo Genes (incomplete)         :: 147 of 186
            Pseudo Genes (internal stop)      :: 2 of 186
            Pseudo Genes (multiple problems)  :: 22 of 186
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:20:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1430106
            Orig. end                         :: 1451237
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031264.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21131
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="6"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21131
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21131
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11131](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11131
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(51..64)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(498..512)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    1031..1048
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.81"
                     /tool="antismash"
     misc_feature    1059..1070
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.15"
                     /tool="antismash"
     gene            complement(1155..2852)
                     /locus_tag="C7M71_RS33135"
     CDS             complement(1155..2852)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018099752.1"
                     /locus_tag="C7M71_RS33135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="discoidin domain-containing protein"
                     /protein_id="WP_407675973.1"
                     /transl_table=11
                     /translation="MLSLDSVTVSRTTGTAPAPLTDPAVPTGGSKVQVTGSQGNWQLTV
                     DGKPYQVKGLTWGPSNDTAGARMRDLKSMGVNTLRTWGTDGGSKPLLDTAAAYGLKVVN
                     GFWLNQGADYVGDTAYKENTLADIRKWVTTYKDHPGVLMWDVGNEVLLTTQDHYSGAQI
                     EQQRIAYAKYVEQVVQAIHAVDPNHPVTSTDAWTGSWVYYKQYTPSLDLYAVNSYGQVC
                     GVRQDWAAGGYTKPYIVTETGEAGEWEVPNDANGVPTEPSDIAKRDAYVSAWDCIKGHT
                     GVALGATIFHYGNENDFGGVWFNIVPSGWKRLAYYSVVKDYGGTAPSNTPPVISSMTVG
                     GATAVAAGSTFTVSASASDPDGDAIRYQLMYSTKYVDGGTGLQQVTFTQTGDGRFSVTA
                     PKRLGVWKVYVYAYDGHGNVGIETRSFRVVAATPSGTNVALSKPTTASSYQATGNGAPF
                     PPSNTTDGKWDTRWASDWSDPQWVQVDLGKTTAVRHVQLGWEAAYAKSYDLQVSDDGNT
                     WRTVYSTSTGSGGVDDVDVTASGRYIRVYMTQRGTAYGYSLYEFGVYA"
     misc_feature    complement(3480..3495)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.64"
                     /tool="antismash"
     gene            complement(<3744..4232)
                     /locus_tag="C7M71_RS33140"
                     /pseudo=""
     CDS             complement(<3744..4232)
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012956.5"
                     /locus_tag="C7M71_RS33140"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="discoidin domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRTAPYPVRPRTLPPPPSLRTAAALILTLGLALYALVVPATRAQA
                     ADALLSQGKPATASSTEGAGYPAAAAVDGDAATRWASAWSDPQWLQVDLGASATLSKAV
                     LTWENYATAYRIQVSDDAAHWTDAYTTTTGTGGTQTVPLSGSGRYVRLYGTARSNGYGY
                     "
     misc_feature    complement(4215..4233)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.38"
                     /tool="antismash"
     misc_feature    complement(4218..4233)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.68"
                     /tool="antismash"
     misc_feature    4372..4388
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.29"
                     /tool="antismash"
     gene            4567..7017
                     /locus_tag="C7M71_RS06250"
                     /old_locus_tag="C7M71_006250"
     CDS             4567..7017
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237395.1"
                     /locus_tag="C7M71_RS06250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006250"
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
                     /protein_id="WP_114914218.1"
                     /transl_table=11
                     /translation="MTTRTLTAGPDLTAHLDDLLARLDLPAKVALLSGCDAFHTPGEPA
                     VGLRGMSVSDGPAGVRGERWDERDTALSLPSPTAQAAAWDEQLVTELGGLLAAEARRKQ
                     VDVLLAPTLNLHRSPFAGRHFECFSEDPLLTARTGAAYIRGVQAGGVAATAKHYVANES
                     ETERLTLDARVDERTLHEVYLAPFEEAVRAGVWLVMSAYNRVNGTTMSESPLLAEPLKG
                     DWGFDGVVVSDWGAVRSTEAAARADQDLAMPGPHPLWGDALVAAVREGRVPEAAVDAKV
                     RRILLLAARVGALESVPGPAAPPAPADPAGLLRRAVAAGSVLLRNEGGLLPLDPARLRR
                     IAVLGQGAAQARIQGGGSAGVFPASVVSPLDGIRAALEGQAEVVHAAGPLLSVRPTPLH
                     PGNARNPATGEPGVLVRYLAEDGGEVHREHRLSGRVLEPAAGPEAVEGAASVEVSALVR
                     PGAAGRWSISVVGLGAVVLEADGRTLLDTHVTPASQDPTYLHVAPSFRSAEVEVTEDQE
                     ILLVARRRFEPDTGRVVALAADPPRPDQDEAVAQAVRAARGADVAVVVVGTTDEIESEG
                     FDRASLALPGRQDDLVRAVVAANPRTVVLVNSGGPVELPWREEVPGVLVGWFPGQEGGH
                     GLADVLFGRAEPGGRLPTTWAATAEGAPLPAVTPEQGVLDYAEGPDIGYRAWLRSGAEP
                     AYWFGHGLGYTTWEYEELTAPQRIDPAAGAEVRVRLRNTGARPGREVVQLYLDAGDGLR
                     LAGYAAVTAGPGERTEAVVRLAPRTFRQWSPQAAGFVDRPGRYTLHAGSSAGRLPLSAR
                     STVG"
     gene            7140..7856
                     /locus_tag="C7M71_RS06255"
                     /old_locus_tag="C7M71_006255"
     CDS             7140..7856
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018101568.1"
                     /locus_tag="C7M71_RS06255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006255"
                     /product="VOC family protein"
                     /protein_id="WP_111493896.1"
                     /transl_table=11
                     /translation="MTSTESSPERIRPQQFHETAGLEDWRVLGEGACAYFRTGSFAVGA
                     RLVQEISGLTGLGDRHPDIDLRPEGVTVRLITITADYYGLSERDAELARRISAVAHKLD
                     LPADPSAVQTVQVTIDALVGPEVVPFWRALLGYQDRANSPEDLIDPHRRGAPFYFQQMD
                     APRPQRNRVHVDVWVPYDQAEARIAAAVAAGGRLVTDAHAPSHWVLADPEGNEACVGAA
                     GWTGPAPEATSPSDAG"
     gene            complement(7903..8802)
                     /locus_tag="C7M71_RS06260"
                     /old_locus_tag="C7M71_006260"
     CDS             complement(7903..8802)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016435832.1"
                     /locus_tag="C7M71_RS06260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006260"
                     /product="hypothetical protein"
                     /protein_id="WP_111493894.1"
                     /transl_table=11
                     /translation="MSVGYLVLYAAFVVVALWLVAELLLQNKAPLVWRAVALAGFLGVV
                     GGMALGSVAVIGLGAAAFAVGQTFVTLSVKRGYQAGWSLRGPDGSLPGPLSRIPFLAGA
                     VGGSLAEPPVAQVGEVGPVEPAYAPGPPAAEAEPPQQPAGQPVYAMQPLSEDDDSDGYG
                     VYTGATTATQEGYYDASYAGYPQQDPYAAAYQGGYDQTQYSATAAYQGQQGYYDASYAG
                     YPQQDPYAAAYQGGYDQTQYSPAATGYTDWSQQQSQPQPQPQPYADYGTQQYTVPEQQQ
                     PPEPPQPPQQPGGWQPSA"
     misc_feature    8898..8911
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            complement(8941..9858)
                     /gene="metF"
                     /locus_tag="C7M71_RS06265"
                     /old_locus_tag="C7M71_006265"
     CDS             complement(8941..9858)
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018382643.1"
                     /locus_tag="C7M71_RS06265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006265"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_111493892.1"
                     /transl_table=11
                     /translation="MALGIPSTRTDRAVTVRDLLAEGHRSFSFEFMPPRTEQGERKLWD
                     AIRRLEALAPNFVCMTYGAGGKSRDRTVDMVGRIASETTLTPVAHLTAVDHSVAELRNI
                     IGHYADEGVRNVLAVRGDPPGDPMGEWVPHPDGVRYASELVELIKGIGDFCVGVAAFPE
                     MHPRSATWEEDIRHFIAKVRAGADYAITQMFFHVEDYLRLRDRVAAAGCEVPIIPEIMP
                     VTNVKQIDFFARLSNAAFPAELAERVLAVADDPAAVRAVGVEYATGMAERLLAEDAPGL
                     HFITLNHSTATLEIYQNLGLHERV"
     gene            10001..11131
                     /locus_tag="C7M71_RS06270"
                     /old_locus_tag="C7M71_006270"
     CDS             10001..11131
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135284.1"
                     /locus_tag="C7M71_RS06270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006270"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_229758568.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.5e-44, bitscore:
                     148.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLPADAAAALLREPVGNPVDQEGLRVRVNEALAEFMDRQEVLLA
                     KISPQLVEASSALRDFLLDGGKRLRPAFCYWGWRGAGGPVGADGIVAAATALELLQASA
                     LIHDDLMDRSDTRRGLPSVHRRFEALHRAGGWRGDRAQYGTAAAVLLGDMLLCWCDELF
                     LRCGLDPAAVLAAKPVFDLMRTEVMAGQYLDVLEPVAGDSMGEGAADRALAVVRYKSAK
                     YTVERPLQVGAVLAGAGPALLEAYSAFGLPLGEAFQLRDDQLGVFGDPAVTGKPAGDDL
                     REGKRTLLVALAMESCAPAEARLLDERLGAPDLEPAEVERLRGIIARSGAADRVEQRID
                     ALLGEALAALEAAPLADGQARDTLRALASAATTRRY"
     gene            complement(11189..11854)
                     /gene="thiE"
                     /locus_tag="C7M71_RS06275"
                     /old_locus_tag="C7M71_006275"
     CDS             complement(11189..11854)
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976712.1"
                     /locus_tag="C7M71_RS06275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006275"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_111493890.1"
                     /transl_table=11
                     /translation="MADTDTPGLPARARLADARLYLCTDARRDQGDLPEFLDAVLAGGV
                     DIVQLRDKALEAAEELETLEVFADACRRHGRLLAVNDRADVAHAARPDVLHLGQGDLPV
                     PYARAILGDEVVIGRSTHAEAEVDAAVTEPGVDYFCTGPVWPTPTKPGRHAPGLGLVRY
                     AAQLRPTRPWFAIGGIDAGNLDQVLAAGARRVVVVRAITAADDPGAAAADLARRLRTG"
     gene            complement(11859..12224)
                     /locus_tag="C7M71_RS06280"
                     /old_locus_tag="C7M71_006280"
     CDS             complement(11859..12224)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129955.1"
                     /locus_tag="C7M71_RS06280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006280"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_111493888.1"
                     /transl_table=11
                     /translation="MSEIDPKIDALVPAWLYLPDISEQWGVEVTRVRQMVKDGVLIAVR
                     RGENNALQVPADFIGDDKPVKGLLGTLTVLRDSGFSDAEALEWLFTEDPTLPGTPVQAL
                     RENRGTEVKRRAQAMAV"
     gene            complement(12349..13512)
                     /locus_tag="C7M71_RS06285"
                     /old_locus_tag="C7M71_006285"
     CDS             complement(12349..13512)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238820.1"
                     /locus_tag="C7M71_RS06285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006285"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_229759065.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.7e-48, bitscore:
                     163.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGAQTAAALRQQGWTGRLTLLGDEPHPPYDRPPLSKDVLLGKAD
                     STAFDLDWAALDVELLTGRRALRLDGAARTVHTDAGPVGYDRLVAATGATAVPLPGTQG
                     VPGVHLLRTADDALALRTALRPGVRVVIVGAGWIGAETATAARQLGCAVTVVEAADQPL
                     AGALPADLGRLTRDWYAAAGVELRTGAAVASVEPGAVHLADATRLAADVVVVGIGARPA
                     TGWLHGSGVDLDGGGAVLADARLRTTLPGVHAVGDCASFPSARFATRLTVQHWDNAMLG
                     ARTVAADLLGPDAPPYDPVPYFWSEQFGRMVQYTGHHPSADRLLWRGTPEDASWTVLWL
                     RGDVPVALLAVDRPRDLVQGRRLIERSTPVDPAAAADPGTPLKSAAR"
     misc_feature    complement(13603..13618)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.25"
                     /tool="antismash"
     misc_feature    complement(13604..13613)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.21"
                     /tool="antismash"
     gene            13917..15221
                     /locus_tag="C7M71_RS06290"
                     /old_locus_tag="C7M71_006290"
     CDS             13917..15221
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010043140.1"
                     /locus_tag="C7M71_RS06290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006290"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_111491743.1"
                     /transl_table=11
                     /translation="MRASRLATATALVAALTITATACGGGGSSSGSPKTLTYWASNQGA
                     SLDNDKQVLEPELRKFEKQTGIKVKLEVVPWSDLLNRILAATASGQGPDVLNIGNTWSA
                     SLQATGALLPWDDAAFAKIGGKDRFVPATIASAGAPGQDPAAVPLYSLAYALYYNKKLF
                     QQAGIAAPPTTWDELVADGKKLTKDGHYGLAVEGGNLSENIHNTFVLGKQHGADFFDAS
                     GKPQFDTPEAVAAVKQYIDFIAKDKIAAPGNAEYAANQSLTDFATGKAGMLMWQAAGSN
                     LKSHGMSPDDYGVAPVPFQTASPSGDTAVNSMVAGINLAVFKNTKNKDGALDFVKFMTS
                     DAEQKILNSTYGSLPPVTSAQGDPAFGTPDLKVLSQVLSTSAAPLPQVAQESQYETLVG
                     TAVKNLFAAAAAGKPITDETVKAELTKAQQQMPAS"
     gene            15223..16137
                     /locus_tag="C7M71_RS06295"
                     /old_locus_tag="C7M71_006295"
     CDS             15223..16137
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983242.1"
                     /locus_tag="C7M71_RS06295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006295"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_111491742.1"
                     /transl_table=11
                     /translation="MRERLRRVGLPYLLLIPALILELLIHVLPMVVGALMSFKELTQFY
                     IQDWTGAPWKGLGNYRMAVDFNAPVGKALLHSFWVTCCFTVLSVGLSWLVGTVAAVLMQ
                     DSFRGRGLLRTLFLVPYALPVYAAVITWSFMFQRDTGLVNHVLHDQLHLTSDRPFWLIG
                     GNSFTALVVVSVWRSWPFAFLTLTAGLQNIPRELYEAAAMDGAGVWQQIRKITLPSLRP
                     VNQVLVLVLFLWTFNDFNTPYVLFGKSAPEAADLISIHIYQSSFVTWNFGSGSAMSVLL
                     LLFLLLVTAVYLLLTSRRKGADA"
     gene            16130..17008
                     /locus_tag="C7M71_RS06300"
                     /old_locus_tag="C7M71_006300"
     CDS             16130..17008
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139293.1"
                     /locus_tag="C7M71_RS06300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006300"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_111491741.1"
                     /transl_table=11
                     /translation="MHSDPARGRAASPMAAPASFRWTRRIVLTVLTVFTVTPVLVMVSS
                     SLKPLEDVQGPFRWIPSGFTLRPYVDIWHTVPLAHYFVNSLIVSVSSTVCSVTVAILAA
                     YAVSRYTFRGRRVFTVTVLSTQMFPGILFLLPLFLLFVNIGNATGVALYGSRGGLILTY
                     LTFSLPFSIWMLVGYLDSIPRDLDEAALVDGCGPIRALVRIIIPAARPGIIAVAVYAFM
                     TAWGEVLFASVLTSEETRTLAVGLQGYATQTDVYWNQVMAASLVVSVPVVAGFLLLQRY
                     LVAGLTAGAVK"
     gene            17029..18384
                     /locus_tag="C7M71_RS06305"
                     /old_locus_tag="C7M71_006305"
     CDS             17029..18384
                     /EC_number="3.2.1.21"
                     /GO_function="GO:0008422 - beta-glucosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030245 - cellulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513118.1"
                     /locus_tag="C7M71_RS06305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006305"
                     /product="GH1 family beta-glucosidase"
                     /protein_id="WP_111491740.1"
                     /transl_table=11
                     /translation="MNDLSALPDDFVWAAATAAYQIEGAVEEDGRSPSIWDTFSHTPGK
                     VDNGDTGDIACDHYHRWPEDLGLMDRLGLGAYRFSIAWPRVMPEGGGAVNPAGLAFYDR
                     LTDALLEAGITPYPTLYHWDLPQAQQDRGGWPERETAERFAEYASVVAGALGDRVTHWA
                     TLNEPLCSAWIGHLEGKMAPGLTDLTAAVRASYHLHLGHGLAVQALRAAVPGAQIGIVN
                     NLSPCEPASDSDADRAAALRADGHTNRWWLDPIHGRGYPEDMVKLYGVELPVRAGDLET
                     IAAPLDWLGLNYYFRQVVADDPTGPVPYARQMPGPDPRRTAMDWEVHGEGLETLLVRLS
                     EEYGAQRVYVTENGSAYQDTVGPDGEVHDPERTAYLEEHLAACARAAARGVPVAGYFAW
                     SLLDNFEWAYGYDKRFGLVHVDYETQRRTMKTSGRRYAELIAAHRTRTRSAV"
     regulatory      18539..18651
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(18608..18621)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            18646..19815
                     /gene="thiO"
                     /locus_tag="C7M71_RS06310"
                     /old_locus_tag="C7M71_006310"
     CDS             18646..19815
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608022.1"
                     /locus_tag="C7M71_RS06310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006310"
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_111491746.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.4e-07, bitscore:
                     28.2, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 1.7e-69, bitscore: 233.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRTETDVLVVGGGIIGLAVAWQTAQRGLSVAVLDPDPGHGAAQV
                     AAGMLAPVTELQYGEEPLLRLGMASNARYAAFAAELEEVSGLSTGYRACGTLAVALDSD
                     DRAELLELYAFHQRLGLDSTWLTGREARRLEPMLAPSVRGGLHVAEDHQVDGRRVGAAL
                     VAACRRAGVRLVPAAAARLTVRSDRATGAVADSGEEFTADQVVLAAGSRSHLLPGLPDG
                     VLPPVRPVKGQVVRLRVPPVYAPFLSRNVRAVVRGCHIYLVPREDGELVIGATTEELGY
                     DTTVTAGGVYELLRDAHELIPGITELPLVETGAGLRPGSPDNAPLLGPTALPGLVAATG
                     HHRNGVLLTPVTGDLIAEYLATGRLPELAAPFLTSRFSRTPTLAQEVLR"
     gene            19812..20036
                     /gene="thiS"
                     /locus_tag="C7M71_RS06315"
                     /old_locus_tag="C7M71_006315"
     CDS             19812..20036
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608023.1"
                     /locus_tag="C7M71_RS06315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006315"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_175607642.1"
                     /transl_table=11
                     /translation="MTAPHPPQIALSVNGEPRRVPGGATLADVVATLSSAPSGVAAAVN
                     EAVVPRSAWGATPLAEDDRIEILTAVQGG"
     gene            20040..20846
                     /locus_tag="C7M71_RS06320"
                     /old_locus_tag="C7M71_006320"
     CDS             20040..20846
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019521974.1"
                     /locus_tag="C7M71_RS06320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M71_006320"
                     /product="thiazole synthase"
                     /protein_id="WP_111491739.1"
                     /transl_table=11
                     /translation="MADDVLTIAGTAFTSRLIMGTGGAPSLEVLEQALRVSGTELTTVA
                     MRRVDPTVKGSVLEVLARNSIRVLPNTAGCFTAGEAVLTARLAREALGTDWVKLEVVAD
                     ERTLLPDPVELLEAAETLVDDGFTVLPYTSDDPVLARRLEEVGCAAVMPLGSPIGSGLG
                     IRNPHNFQLIVENAGVPVVLDAGAGTASDAAFAMELGCDAVMLASAVTRAQDPALMADA
                     MRRAVEAGRLARRAGRIPRRFHAEASSPLAGRAELDHREMPAFQTF"
ORIGIN
        1 cgtaccagct ccggcttgaa gatcaccgag gtcacccgct ggtccggccg ctcgatccgg
       61 tccagcagca gccgcgccat ctcggccgcc atgtcctcca ccggctgccg caccgtggtc
      121 agctgcggcc gggcggcgag cgcggcgctg ctgtcgtcga acccgaccac cgcgacatcc
      181 tcggggaccc gccgcccccg gtcgcgcagc gccagcaggg cgccctgggc catcaggtcg
      241 ttggccacga agacgccgtc ggtctgcggg tgctcggcca gcagccgcgc catggcccgc
      301 tccccgccgt cctgggtgaa gttgccctcc acgctgggtg cgaaggcgtg cccgtgctcg
      361 gccatggcct cgcggaagcc ggccagccgg tcctgtccgg ccggggcgtc cagcgggccg
      421 gagacggtgg cgatatgccg gcagccccgg gcgagcagat gctcggtggc cagccgggcg
      481 ccggcgtggt gggccacgtc gacatagctg atcgggacgg gcgtcgtcgg ccgggcgaag
      541 agcacggtgg gcacctcggt ctcggtgagc agccggggca gcgggtcgcc cggggcgatg
      601 gagaccagca ccacgccgtc gatgcgctgc tgctgaagct cggcgagcag ggcggtgcgg
      661 ctgtacgggg agtcggcgag catcagcagc ggatgcaccc cgcgcgggcg gaagacggtg
      721 agcagcccgc cgacgatccg gccgaagaag gggtcgctga agacctggcc caggaagggg
      781 tcctgttcgg cgtggacctc gggcaccgag aagaccaggg cgacggcgtc ggtgcggcgg
      841 gtgaccagcg accgcgccgc ccggttgggc acatagccgg tggccgccac cgccgccagc
      901 acggccttgc ggatctccgg gtcgacattg cgggtctcgt tgacgacccg ggagacggtg
      961 gcccgggaga ctccggcgga ccgggcgacg tcttcgaggg tcggcaggcg tggccccgcc
     1021 ggacggctgc tggtcatgga gctgttatac cacgctcgga aagcgctctc cgaggcaaag
     1081 ccgcagaccg ggcggggtac ggcggcggtc ggtaccgcgc cgccgtaccc cgctccaggc
     1141 cggacgggat cggctcaggc gtagacgccg aactcgtaca gcgagtagcc gtaggccgtc
     1201 ccccgctgcg tcatatagac ccggatgtag cggccggagg cggtgacgtc gacatcgtcg
     1261 accccgccgc tcccggtgga cgtggagtac acggtccgcc aggtgttgcc gtcgtccgag
     1321 acctggaggt cataggactt ggcgtaggcc gcctcccagc cgagctgcac atgccgcacg
     1381 gcggtggtct tcccgaggtc cacctggacc cactgggggt cgctccagtc gctggcccag
     1441 cgggtgtccc acttgccgtc ggtggtgttc gacggcggga agggcgcccc gttgccggtg
     1501 gcctggtacg aggaggcggt ggtgggcttg gagagcgcca cattggtccc gctcggggtg
     1561 gcggccacca cccggaagga gcgggtctcg atgcccacgt tgccgtggcc gtcgtaggcg
     1621 tagacataga ccttccacac cccgagccgc ttgggcgcgg tcaccgagaa ccggccgtcc
     1681 ccggtctggg tgaaggtcac ctgctggagt ccggtgccgc cgtcgacgta cttggtggag
     1741 tacatcagct ggtagcggat ggcatcgccg tccgggtcgc tcgccgaggc ggagacggtg
     1801 aaggtggagc cggccgccac cgccgtggcg ccgccgaccg tcatgctgct gatcaccggc
     1861 ggggtgttgg acggcgcggt gccgccgtag tccttgacga ccgagtagta cgccagccgc
     1921 ttccagccgc tgggcacgat gttgaaccag acgccgccga agtcgttctc attgccgtag
     1981 tggaagatcg tggcgcccag cgccactccg gtgtggccct tgatgcagtc ccaggcggac
     2041 acataggcgt cgcgcttggc gatgtcggag ggctcggtgg ggacgccgtt ggcgtcgttg
     2101 ggcacctccc actcgccggc ctcaccggtc tcggtgacga tgtacggctt ggtgtagccg
     2161 ccggccgccc agtcctgcct gaccccgcag acctggccgt aggagttcac cgcgtagagg
     2221 tccaggctcg gcgtgtactg cttgtagtag acccaggagc cggtccaggc gtcggtggag
     2281 gtcaccgggt ggttcgggtc gacggcgtgg atcgcctgca ccacctgctc cacatacttg
     2341 gcgtaggcga tgcgctgctg ctcgatctgg gcgccggagt agtggtcctg cgtggtcagc
     2401 agcacctcgt tgccgacgtc ccacatcagc acgccggggt ggtccttgta ggtggtgacc
     2461 cacttcctga tgtcggcgag ggtgttctcc ttgtacgcgg tgtcgcccac gtagtcggcg
     2521 ccctggttga gccagaagcc gttgaccacc ttcagcccgt aggcggcagc ggtgtccagc
     2581 agcggtttgc tgcccccgtc ggtgccccag gtgcgcaggg tgttgacgcc catcgacttg
     2641 aggtcgcgca tccgggcgcc ggcggtgtca ttggagggcc cccaggtcag gcccttgacc
     2701 tggtacggct taccgtccac ggtgagctgc cagttgccct gggagccggt gacctggacc
     2761 ttgctgccgc cggtgggcac cgcggggtcg gtgagcgggg cgggggcggt gccggtggta
     2821 cgggagacgg tgaccgagtc caggctgagc acgccgccgg aggaggtgtc ggcggccggg
     2881 gtggtgcagc cgcagacggc gtccgggtac gagccgccga tgccgaggtt gaacaccagg
     2941 aagaagccgt ggtgcacggc ggcgttccag gcggcggtgc cgacctggct ctcgttgacc
     3001 tgccagacct gcgcgccgtc caggtaccag cggatctgct cgtcggagcg ggtgcggtcg
     3061 atgacggtgg cgtaggtgtg gtagccggtc tggcagccgg tgcagctggc caggccgctg
     3121 gtcataccgt cgtactcatt gcagttgccg ccgggggcgg tgccgcagtg cagggtcgcc
     3181 gacagctggc tgcggccgtt gacgttctcc aggatgtcca gctcgccgac gccgggccag
     3241 gtcgaggggg cggcccggta gccggcgccc agggcgcgga aggacggcca gtagcccagc
     3301 gcccggtcgg ggttgggctg cttgatggtg gcggagatct gcaactggcc gccggccggg
     3361 gcctcgaagt cggtgcgctt ggtctccacc cggccggagg tccaggcggt gccggacttg
     3421 accgcggtga ggttgaggtg gccgctgccg tcgagggaga cattggcacg gtcggcggtg
     3481 gaggtctcga cctcgccggt gccccagtgg gcggagccgc cggggtaggc ggtgccggtg
     3541 tcggtgatcc aactgccgct gtcgggggcg gagccggccg cgccggagaa gtcgtcgctc
     3601 cagacggtgg tccagttgcc gggcggggtg gtgccaccgc cggtcgtccc gccggtcgta
     3661 ctaccgccgg tcgtaccgct ggtcgtcccg ccggtcccgc cgcccgtccc gggggtgccg
     3721 tagacctgga actcccagag cgagtagccg tagccgttgg accgggcggt cccatagagc
     3781 cgcacatagc gcccgctgcc gctcagcggg acggtctggg tcccgccggt gccggtggtg
     3841 gtggtgtagg cgtcggtcca gtgcgcggcg tcgtcggaga cctggatgcg ataggcggtg
     3901 gcgtagttct cccaggtcag gacggccttg ctgagggtgg ccgaggcgcc caggtccacc
     3961 tggagccact gcgggtcgct ccaggcactg gcccagcggg tggcggcgtc gccgtcgacg
     4021 gccgccgccg ccgggtagcc ggcgccctcg gtggaggagg cggtggccgg cttgccctgg
     4081 gagagcagtg cgtcggcggc ctgcgcacgg gtggccggga ccaccagggc gtacagcgcc
     4141 aggcccagcg tgaggatcag cgcggcggcg gtgcgcagcg atggcggcgg tggcagggtg
     4201 cgggggcgca ccgggtaggg agcggttctc attgcggcgg ctcctggggg gaaggagggc
     4261 ggacggagag catgccttgg agagcgctct ctcgtggggc gatggtcgcg gtccggtttc
     4321 cggggtgtca agagatgtgg cagcaccccg cgagaagccg cctcggcgta tccgatacat
     4381 catcacttgt ccgggcagat cgccggtccg atcgcccccg cccgcccggc gggggcttga
     4441 cgtactccgc cgagccgcgt gactgttgcc tggagagcgc tctccaccag cgttcaccga
     4501 ccgcgttcac cgacagcgct caccgccgca cttccacgat ggaacaggcc ctgcgaaggg
     4561 atcaccatga ccacccgcac cctcacggcc gggccggacc tcaccgccca cctggacgac
     4621 ctgctcgccc gcctcgacct gcccgccaag gtggccctgc tgtccggctg cgacgccttc
     4681 cacaccccgg gcgaaccggc cgtcggcctg cgcgggatga gcgtctccga cggcccggcc
     4741 ggggtgcgcg gcgagcgctg ggacgagcgc gacaccgccc tctcgctgcc ctcacccacc
     4801 gcccaggccg ccgcctggga cgagcagttg gtcaccgaac tcggcgggct gctcgccgcc
     4861 gaggcccgcc gcaagcaggt cgacgtgctg ctggccccca ccctcaacct gcaccggtcc
     4921 ccgttcgccg gccgccactt cgagtgcttc tccgaggacc cgctgctcac cgcccgcacc
     4981 ggggccgcct acatccgggg cgtccaggcc ggcggagtcg ccgccaccgc caagcactat
     5041 gtggccaatg agtccgagac cgagcggctg accctggacg cccgggtcga cgagcgcacc
     5101 ctgcacgagg tgtacctcgc ccccttcgag gaggcggtgc gcgccggggt ctggctggtg
     5161 atgtcggcgt acaaccgggt caatggcacc accatgtcgg agagcccgct gctcgccgaa
     5221 cccctcaagg gcgactgggg attcgacggg gtggtggtct ccgactgggg cgcggtgcgc
     5281 tccaccgagg ctgccgcccg cgccgaccag gacctggcca tgcccggccc gcacccgctc
     5341 tggggcgacg ccctggtggc cgccgtacgc gaggggcggg taccggaggc cgcggtggac
     5401 gccaaggtcc ggcggatcct gctgctggcc gcccgggtcg gcgccctgga gagcgtgccc
     5461 ggccccgccg cgccgcccgc gcccgccgac ccggcggggc tgctgcggcg ggccgtcgcg
     5521 gcgggcagcg tcctgctgcg caacgagggc ggcctgctgc cgctggaccc ggcccggctg
     5581 cggcggatcg ccgtcctggg gcagggcgcg gcgcaggccc gcatccaggg cggcggcagc
     5641 gcgggcgtct tccccgcctc cgtggtctcc ccgctggacg gcatccgggc cgcgctggag
     5701 ggccaggccg aggtggtgca cgccgccggg ccgctgctca gcgtccgccc cacgccgctg
     5761 caccccggca atgcgcgcaa cccggccacc ggggagcccg gcgtcctggt ccgctacctc
     5821 gccgaggacg gcggcgaggt gcaccgcgag caccggctca gcggccgggt gctggagccc
     5881 gccgccgggc ccgaggcggt cgagggcgcg gcgagcgtgg aggtcagcgc cctggtgcgg
     5941 ccgggcgcgg ccggccggtg gagcatctcg gtggtcggcc tgggcgcggt ggtactggag
     6001 gcggacggcc gcaccctgct ggacacccat gtcacccccg cctcgcagga ccccacctat
     6061 ctccatgtgg cgccctcctt ccgcagcgcg gaggtcgagg tgacggagga tcaggagatc
     6121 ctgctggtcg cccggcggcg ctttgagccg gacaccggcc gggtcgtcgc cctcgctgcg
     6181 gacccgccgc gcccggacca ggacgaggcc gtcgcgcagg cggtgcgggc ggcgcgcggc
     6241 gccgatgtgg ccgtggtggt ggtcggcacc accgacgaga tcgagagcga ggggttcgac
     6301 cgggcctccc tcgcgctgcc cggccgccag gacgacctgg tgcgggcggt ggtcgcggcc
     6361 aacccgcgga ccgtggtgct ggtcaactcc ggcggcccgg tggagcttcc ctggcgggag
     6421 gaggtaccgg gcgtgctggt cggctggttc cccggccagg agggcgggca cggcctggcg
     6481 gatgtgctct tcggccgggc cgagccgggc ggccggctgc ccaccacctg ggcggccacg
     6541 gcggagggcg ccccgctgcc cgccgtcacg ccggagcagg gcgtgctgga ctacgcggag
     6601 gggcccgaca tcggctaccg ggcatggctg cggtccggcg ccgagcccgc ctactggttc
     6661 ggccacgggc tgggctacac cacctgggag tacgaggagt tgaccgcccc gcagcggatc
     6721 gacccggcgg ccggggcgga ggtccgggtg cggctgcgca acaccggtgc ccggccgggc
     6781 cgcgaggtgg tgcagctcta cctcgacgcg ggcgacggcc tgcggctggc cgggtatgcg
     6841 gcggtcacgg ccgggcccgg tgagcggacc gaggcggtgg tccgcctggc gccgcgcacc
     6901 ttccggcagt ggtcgccgca ggcggccggc tttgtggacc ggccgggccg gtacaccctg
     6961 cacgccggct cctcggccgg acggctgccg ctgtcggcgc ggtccaccgt gggctgaccg
     7021 gcgcctcccc gctccgggac cgggtcctcc gtacgctgct gcggacccgg tcccggtccc
     7081 ggtcccggcg atggccacgg ccgacgggga ttgtcggacc cgcccgctac gttgggccaa
     7141 tgacctctac cgagagcagt cccgagcgga tcaggccgca gcagttccat gagaccgccg
     7201 gcctggagga ttggcgggtg ctgggtgagg gggcctgcgc gtacttccgc accgggtcgt
     7261 tcgcggtcgg cgcccggctg gtgcaggaga tcagcgggct caccggcctc ggggaccgcc
     7321 accccgacat cgatctgcgg cccgagggcg tgaccgtacg gctgatcacg atcacggccg
     7381 actactacgg gctgagcgag cgggacgccg agctggcccg gcggatctcg gcagtggccc
     7441 acaagctgga cctccccgcc gacccgtccg cggtgcagac cgtccaggtc accatcgacg
     7501 ccctcgtcgg tcccgaggtg gtgccgttct ggcgtgccct gctcgggtac caggaccgcg
     7561 ccaacagccc cgaggacctg atcgatccgc accgccgtgg ggcgccgttc tacttccagc
     7621 agatggacgc gccgcgcccg cagcgcaacc gggtccatgt cgacgtctgg gtgccgtacg
     7681 accaggccga ggcgcggatc gcggcggcag tcgccgccgg gggccgcctg gtgacggatg
     7741 cccatgcgcc gtcgcactgg gtgctggccg accccgaggg caatgaggca tgtgtcggcg
     7801 cggccggctg gaccgggcct gcccccgagg ccacctcacc gtcggacgcg gggtgagcgc
     7861 tgaggggccc gctggtcgta ccggactgcg gcggccaccc gctcaggcgg agggctgcca
     7921 gccgcccggc tgctgcggcg gctgcggagg ctccggtggc tgctgctgct cggggacggt
     7981 gtactgctgg gtgccgtagt cggcgtacgg ctgcggctgc ggctgcggct gcgactgctg
     8041 ctgcgaccag tcggtgtagc cggtggcggc ggggctgtac tgggtctggt cgtagccgcc
     8101 ctggtacgcc gccgcatagg ggtcctgctg cggataaccg gcgtaggagg cgtcgtagta
     8161 gccctgctgg ccctggtagg cggcggtggc gctgtactgg gtctggtcat agccgccctg
     8221 gtacgccgcc gcatacgggt cctgctgcgg ataacccgca taggaggcgt cgtagtagcc
     8281 ctcctgggtg gcggtggtcg cgccggtgta gaccccgtag ccgtcggagt cgtcgtcctc
     8341 gctcagcggc tgcatcgcat acaccggctg cccggcgggc tgctgcggcg gctccgcctc
     8401 ggcggccggg gggccggggg cgtacgccgg ttccaccggg ccgacctcgc cgacctgcgc
     8461 caccggcggc tccgccaggc tgccgccgac cgctccggcc aggaagggga tgcgggacag
     8521 cggcccggga agggagccgt ccggcccgcg cagcgaccag ccggcctggt agccgcgctt
     8581 gacggagagg gtgacaaagg tctgccccac cgcgaaggcc gccgcgccca gtccgatgac
     8641 cgccaccgac cccagcgcca tcccgccgac caccccgagg aagcccgcca gcgccaccgc
     8701 ccgccagacc agcggagcct tgttctggag cagcagttcg gcgaccagcc agagcgccac
     8761 gaccacgaac gcggcgtaca gcaccaggta cccgacgctc acgaaacctc cactcaccgg
     8821 cccggcgccg ccgcccggcc caccccgtcc cggcccaccc gcgccgcgcg tgtcgagcga
     8881 gcgtaccgtg ccgccgcggc acgggtgttg ccaccgggcc ggggtttgcg gcggtgcggg
     8941 tcagacccgc tcgtggagcc ccaggttctg gtagatctcc agcgtcgccg tggagtggtt
     9001 gagcgtgatg aagtgcaggc cgggcgcgtc ctcggccagc agccgctccg ccattccggt
     9061 ggcgtactcc acgccgaccg cgcggaccgc cgccgggtcg tccgcgaccg ccagcacccg
     9121 ctcggccagc tccgccggga aggccgcatt gctgagccgg gcgaagaagt cgatctgctt
     9181 gacgttggtg accggcatga tctccgggat gatcggcacc tcgcagccgg cggcggcgac
     9241 ccggtcgcgc agccgcaggt agtcctccac atggaagaac atctgggtga tggcgtagtc
     9301 ggccccggcg cgcaccttgg cgatgaagtg ccggatgtcc tcctcccagg tggcggagcg
     9361 ggggtgcatc tccgggaagg ccgcgacgcc cacgcagaag tcgccgatgc ccttgatcag
     9421 ctccaccagc tcggaggcat agcggacgcc gtccgggtgg ggcacccact cgcccatcgg
     9481 gtcgccgggc gggtcgccgc gcacggccag cacattgcgt accccctcat cggcgtagtg
     9541 gccgatgatg ttgcgcagct cggcgaccga gtggtcgacg gcggtgaggt gggccaccgg
     9601 ggtgagggtg gtctcgctgg cgatcctgcc gaccatgtcg acggtgcggt cccgcgactt
     9661 gccgccggcg ccgtaggtca tgcagacgaa gttgggggcg agcgcctcca gtcggcggat
     9721 ggcatcccac agctttcgct cgccctgctc ggtccggggc ggcatgaact cgaaggagaa
     9781 ggagcggtgc ccttccgcca gcaggtcgcg gacggtgacc gcgcggtccg ttctggtgga
     9841 ggggataccg agtgccataa gggcaggtta tccgcgatac ggacggtcgg ggcactccgc
     9901 gtccacctcg tgagacgcgg tatcggccgg gcggctgcgc ggggtggaca ggtgtccggt
     9961 taggctggct gtcccccgct ttatccaccg gagccgcacc gtgaccctgc ccgccgacgc
    10021 cgccgccgca ctcctccggg agcctgtcgg caaccccgtg gaccaggagg ggctgcgcgt
    10081 ccgcgtcaac gaggcgcttg cggagttcat ggaccggcag gaggtgctgc tggccaagat
    10141 ctcgccgcag ctggtggagg cgtcctcggc gctgcgcgac ttcctgctgg acggcggcaa
    10201 gcggctgcgt cccgccttct gctactgggg ctggcgcggc gccggcggcc cggtcggcgc
    10261 ggacgggatc gtggcggcgg cgaccgccct ggagctgctc caggccagtg cgctgatcca
    10321 tgacgacctg atggaccgca gcgacacccg gcgcgggctg ccctccgtgc accgccgctt
    10381 cgaggcgctg caccgggccg gcggctggcg cggcgaccgc gcgcagtacg gcacggccgc
    10441 cgcggtgctg ctgggcgaca tgctgctctg ctggtgcgac gagctgtttc tgcggtgcgg
    10501 gctggacccg gcggcggtgc tggccgccaa gccggtcttc gacctgatgc gcaccgaggt
    10561 gatggccggg cagtacctgg acgtgctgga gccggtcgcg ggcgactcca tgggcgaggg
    10621 cgcggcggac cgggcgctgg ccgtggtccg ctacaagtcg gccaagtaca cggtggagcg
    10681 tccgctccag gtgggcgcgg tgctggcggg tgccgggccg gcgctgctgg aggcgtactc
    10741 ggcgttcggt ctgccgctcg gcgaggcgtt ccagctgcgc gacgaccagc tgggggtctt
    10801 cggcgacccg gcggtgaccg gcaaaccggc cggtgacgac ctgcgggagg gcaagcgcac
    10861 cctgctggtg gcgctggcca tggagtcctg cgcccccgcc gaggcgcggc tgctggacga
    10921 gcggctgggc gccccggatc tggagcccgc cgaggtggag cggctgcgcg ggatcatcgc
    10981 ccggagtggt gcggccgatc gggtggagca gcggatcgac gcgctgctgg gcgaggcgct
    11041 ggcggcgctg gaggcggctc cgctggccga cgggcaggcc cgcgacacgc tgcgggcgct
    11101 ggcctcggcg gcgaccaccc ggcggtactg agcgcggtgc ggaagagggg gttccggggg
    11161 cggcggggcg cccccggaac ccggtcggtc atccggtgcg cagccggcgg gccaggtcgg
    11221 cggcggcggc cccggggtcg tccgccgcgg tgatcgcccg gaccaccacg acccggcggg
    11281 cgccggccgc cagcacctgg tcgaggttgc cggcgtcgat gccgccgatg gcgaaccacg
    11341 gccgggtcgg ccgcagctgc gccgcgtacc tcaccaggcc gaggccgggg gcgtggcggc
    11401 cgggcttggt cggggtgggc cagaccggtc cggtgcagaa gtagtccacg ccgggctcgg
    11461 tgacggcggc gtccacctcg gcctcggcgt gggtggaccg gccgatgacc acctcgtcgc
    11521 cgaggatcgc ccgggcgtac ggcaccggca ggtcgccctg gcccaggtgg agcacgtcgg
    11581 ggcgggctgc gtgggccacg tcggcccggt cgttgaccgc cagcagccgg ccgtggcggc
    11641 ggcaggcgtc ggcgaagacc tccagggtct ccagctcctc cgcggcctcc agcgccttgt
    11701 cgcgcagctg cacgatgtcg acgccgccgg ccagcaccgc gtccaggaac tcgggcaggt
    11761 cgccctggtc ccggcgggcg tcggtgcaga ggtagaggcg ggcgtccgcc agcctggccc
    11821 gggccgggag gcccggggtg tccgtgtccg ccaccgggtc agaccgccat cgcctgggcg
    11881 cggcgcttga cctcggtgcc ccggttctcc cgcagcgcct gcacgggggt gccgggcagg
    11941 gtggggtcct cggtgaagag ccactccagg gcctcggcgt cgctgaaccc ggagtccctg
    12001 agcacggtca gggtgccgag cagccccttg acgggcttgt cgtcgccgat gaagtcggcg
    12061 gggacctgaa gggcgttgtt ctctcctcgg cgcaccgcga tcagtacgcc gtccttgacc
    12121 atctgacgga cccgggtgac ctccacaccc cactgctcgg agatgtcggg aaggtacagc
    12181 cacgccggga caagggcatc aatcttggga tcgatctcgc tcacccgtcc agactgccat
    12241 ccgtcgggcc ccgatgggta actccgggtg cgtggcggtg ccgcgccgcg cgggccgccg
    12301 gggccccgcc ggggccccgt ggacgcactg caacgggctg ctgggacctc agcgggcggc
    12361 cgacttcagc ggggtgcccg ggtccgcagc ggcggccggg tcgaccgggg tggagcgctc
    12421 gatcagccgc ctgccctgga cgaggtcgcg cggccggtcc acggcgagca gggccaccgg
    12481 gacgtcgccg cgcagccaga gcaccgtcca ggaggcgtcc tcgggggtgc cgcgccagag
    12541 cagccggtcg gcggacgggt ggtgtccggt gtactggacc atccggccga actgctcgga
    12601 ccagaagtac ggcaccgggt cgtagggcgg cgcatcgggg ccgagcaggt cggcggcgac
    12661 ggtgcgggcg ccgagcatgg cgttgtccca gtgctggacg gtcagccggg tggcgaagcg
    12721 ggcggagggg aaggaggcgc agtcgccgac cgcgtgcacc ccgggcaggg tggtgcgcag
    12781 ccgggcgtcg gcgagtaccg cgccgccgcc gtccaggtcc accccggagc cgtgcagcca
    12841 gccggtggcg gggcgggccc cgatgccgac caccaccacg tcggcggcca gccgggtggc
    12901 gtcggcgagg tgcaccgcgc cgggctccac cgaggcgacg gccgcgccgg tgcgcagctc
    12961 gaccccggcg gcggcgtacc agtcgcgggt gagccggccg aggtcggcgg ggagggctcc
    13021 ggccagcggc tggtcggcgg cctcgaccac ggtgacggcg cagccgagct gccgggcggc
    13081 ggtggcggtc tcggcgccga tccagccggc gccgacgatc accacgcgga cgccggggcg
    13141 gagcgccgta cgcagcgcca gcgcgtcgtc ggcggtgcgc agcaggtgga cgccggggac
    13201 gccctgggtg ccgggcagcg gtacggcggt ggcgccggtg gcggccacca gccggtcgta
    13261 gccgaccggc ccggcgtcgg tgtggacggt gcgggcggcg ccgtccagcc gcagggcgcg
    13321 gcggccggtg agcagttcca cgtccagggc ggcccagtcg aggtcgaagg cggtggagtc
    13381 ggccttgccg agcagcacgt ccttggagag cggcggccgg tcgtacgggg ggtgcggctc
    13441 gtcgccgagc agcgtcagcc tgccggtcca gccctgctgc cgcagggcgg cggcggtctg
    13501 ggcaccggcc atgccggcgc cgacgatcac gatcctgtcc ttgccggtcg cttctgccac
    13561 ccggccaatc tacccacctc ccaccgccgc cggggcaggc agggcaaaaa actgggagag
    13621 cgctcgccca atcagtttcc cggccctgac ctgggggtgt caaggcatgt cacgcggacc
    13681 ttcgcggcgg gggcggcccg cggcggggat atgcacctga cgccacctca ccgaccatgg
    13741 gagggtgttt gcgcaggctg cggcggtacg gcggggggac gggggcgagt cggccgatcc
    13801 cgagggcctt taccccttga cgggagagtt tgcccacgcg ttaaatcacg ccctgaagta
    13861 agccgtgatc ctgccggccc tcaccacccg tctgcccctg gaaggggaac cccgacatgc
    13921 gtgcctccag gcttgccacc gccaccgccc tcgtcgccgc cctcaccatc acggccaccg
    13981 cctgcggagg cggcggaagc agctccggca gccccaagac gctcacctac tgggcgagca
    14041 accagggcgc cagcctcgac aacgacaagc aggtcctgga gccggagctc agaaagttcg
    14101 agaagcagac cggcatcaag gtcaagctgg aggtcgtccc ctggtccgac ctgctcaacc
    14161 gcatcctggc cgccaccgcc tccggccagg gcccggacgt gctcaacatc ggcaacacct
    14221 ggtccgcctc gctccaggcc accggggccc tgctgccctg ggacgacgcc gccttcgcca
    14281 agatcggcgg caaggaccgc ttcgtcccgg cgaccatcgc ctcggccggc gcgcccggcc
    14341 aggacccggc ggcggtgccg ctctactcgc tggcgtacgc gctctactac aacaagaagc
    14401 tgttccagca ggccggcatc gcggccccgc ccaccacctg ggacgagctg gtcgccgacg
    14461 ggaagaagct caccaaggac ggccactacg gcctggcggt cgagggcggc aacctctccg
    14521 agaacatcca caacaccttc gtcctcggca agcagcacgg cgccgacttc ttcgacgcct
    14581 ccggcaagcc gcagttcgac acccccgaag cggtggccgc cgtcaagcag tacatcgact
    14641 tcatcgccaa ggacaagatc gcggcccccg gcaacgccga gtacgccgcc aaccagtcgc
    14701 tcaccgactt cgccaccggc aaggccggga tgctgatgtg gcaggcggcc ggcagcaacc
    14761 tgaagtccca cggcatgtcg cccgacgact acggggtggc cccggtcccc ttccagaccg
    14821 cctcgccctc cggcgacacc gccgtcaact ccatggtggc cggcatcaac ctggccgtct
    14881 tcaagaacac caagaacaag gacggcgccc tggacttcgt gaagttcatg accagcgacg
    14941 ccgagcagaa gatcctcaac tccacctacg gctcgctgcc gccggtcacg tccgcgcagg
    15001 gcgacccggc cttcggcacc ccggacctca aggtgctctc ccaggtgctc tccaccagcg
    15061 ccgcgccgct gccgcaggtc gcccaggaga gccagtacga gaccctggtg ggcaccgccg
    15121 tcaagaacct cttcgccgcc gcggcggccg gcaagccgat caccgacgag accgtcaagg
    15181 ccgaactcac caaggcccag cagcagatgc cggcgtcctg acgtgcgtga acgactgcgc
    15241 cgagtcggcc tgccctatct gctcctgata cccgccctga tcctggaact gctcatccat
    15301 gtgctgccga tggtcgtcgg cgccctgatg agcttcaagg agctcaccca gttctacatc
    15361 caggactgga ccggagcccc ttggaaggga ctgggcaact accggatggc ggtggacttc
    15421 aacgccccgg tgggcaaggc gctgctgcac tccttctggg tgacctgctg cttcacggtg
    15481 ctctcggtgg gcctgtcctg gctggtgggg acggtcgcgg ccgtcctcat gcaggactcc
    15541 ttccggggcc ggggcctgct gcggacgctc ttcctggtgc cgtacgcgct gccggtctac
    15601 gccgccgtga tcacctggtc gttcatgttc cagcgggaca ccggcctggt gaaccatgtg
    15661 ctccacgacc agctgcacct cacctccgac cggccgttct ggctgatcgg cggcaacagc
    15721 ttcaccgcgc tggtggtcgt ctcggtctgg cggtcctggc cgttcgcgtt cctcacgctg
    15781 acggccgggc tccagaacat cccgcgcgag ctctacgagg cggcggcgat ggacggggcg
    15841 ggggtctggc agcagatccg caagatcacc ctgccgtcgc tgcgccccgt caaccaggtg
    15901 ctggtgctgg tgctcttcct gtggacgttc aacgacttca acacgccgta tgtgctcttc
    15961 gggaagtccg cgccggaagc cgccgacctg atctccatcc acatctacca atcctccttc
    16021 gtcacctgga acttcggctc gggctcggcc atgtcggtgc tgctgctgct gttcctgctg
    16081 ctggtgacgg cggtctacct gctcctcacc tcccgccgga agggcgccga tgcatagcga
    16141 cccggcacgc ggccgcgccg cctcccccat ggccgcaccc gcctccttcc ggtggaccag
    16201 acggatcgtg ctcaccgtgc tgacggtctt caccgtgacc ccggtgctgg tgatggtgag
    16261 ctcgtcgctg aagccgctgg aggacgtcca gggaccgttc cgctggatac cgagcggctt
    16321 cacactccgc ccctatgtgg acatctggca caccgtgccg ctggcccact acttcgtcaa
    16381 ctcgctgatc gtgtcggtct cctcgaccgt ctgctcggtg acggtggcga tcctcgccgc
    16441 ctacgcggtg agccggtaca ccttccgggg ccgccgggtg ttcaccgtga cggtgctctc
    16501 cacccagatg ttcccgggca tcctcttcct gctgccgctc ttcctgctct tcgtcaacat
    16561 cggcaatgcc accggggtcg cgctctacgg cagccggggc gggctgatcc tcacctacct
    16621 caccttctcg ctgccgttct ccatctggat gctggtcggc tacctggact ccatcccgcg
    16681 cgacctcgac gaggcggccc tggtggacgg ctgcgggccg atccgcgccc tggtgcggat
    16741 catcatcccg gccgcccggc ccggcatcat cgcggtcgcc gtgtacgcct tcatgaccgc
    16801 ctggggcgag gtgctcttcg cctcggtgct caccagcgag gagacccgga ccctcgccgt
    16861 cggactccag ggctacgcca cccagaccga tgtctactgg aaccaggtca tggccgcgtc
    16921 gctggtcgtc agcgtgccgg tggtcgccgg gttcctgctg ttgcagcgct atctcgtcgc
    16981 cgggctcacc gccggcgccg tcaagtgaac ctcttcgaaa ggccccttgt gaacgacctc
    17041 agtgcgctcc ccgacgactt cgtctgggcg gcggccaccg ccgcctacca gatcgagggc
    17101 gccgtggagg aggacggccg ctccccctcc atctgggaca ccttctccca caccccgggc
    17161 aaggtggaca acggcgacac cggcgacatc gcctgcgacc actaccaccg ctggcccgag
    17221 gacctcggtc tgatggacag gctcggcctc ggggcctacc gcttctccat cgcctggccc
    17281 cgggtcatgc ccgagggcgg cggcgccgtc aacccggccg gcctggcctt ctacgaccgg
    17341 ctcaccgacg ccctgctgga agccgggatc accccctacc cgaccctgta ccactgggac
    17401 ctcccccagg cgcagcagga ccggggcggc tggccggagc gcgagaccgc cgagcggttc
    17461 gccgagtacg cgtcggtggt cgccggggcg ctgggcgacc gggtcaccca ctgggccacc
    17521 ctcaacgagc cgctctgctc ggcctggatc ggccacctcg aaggcaagat ggctcccggc
    17581 ctgaccgacc tcaccgccgc cgtccgggcc tcgtaccacc tccacctggg ccacggcctg
    17641 gccgtgcagg ccctccgggc cgccgtcccc ggtgcgcaga tcggcatcgt caacaacctc
    17701 agcccgtgcg agcccgcgag cgacagcgac gccgaccgcg ccgccgcgct ccgtgccgac
    17761 ggccacacca accgctggtg gctggacccg atccacgggc gcggctaccc cgaggacatg
    17821 gtcaagctgt acggggtgga actcccggtc cgcgcggggg acctggagac catcgcggcg
    17881 ccgctggact ggctgggcct gaactactac ttccgccagg tcgtcgccga cgacccgacc
    17941 ggcccggtcc cgtacgcccg ccagatgccc ggccccgacc cgcgccgcac cgcgatggac
    18001 tgggaggtgc acggcgaggg cctggagacg ctgctggtgc ggctctccga ggagtacggc
    18061 gcgcagcggg tgtacgtcac cgagaacggc tcggcctacc aggacacggt cggcccggac
    18121 ggcgaggtgc acgacccgga gcggaccgcc tacctggagg agcacctggc cgcctgcgcc
    18181 cgcgccgccg cccggggcgt cccggtggcg gggtacttcg cctggtcgct gctggacaac
    18241 ttcgagtggg cgtacggcta cgacaagcgg ttcggcctgg tccacgtcga ctacgagacc
    18301 cagcgccgca ccatgaagac cagtggccgc cgctacgccg agctgatcgc cgcgcaccgc
    18361 acccgcaccc gctcggccgt ctgaccggcg cccccgcacg gggcgcacac caccgcgcac
    18421 acccacgcac acgcacacgc acgcgcaccc acgcaccacc gcacacacca ccgcacacac
    18481 cgctgcacca ccgcgccccg gggcccttcg aggtcaccgg ggcgcggcga taggctgggg
    18541 gcgtacacgc gggagcccgg cgcaccgggc tgagagggag gctggagcgg cctccgaccg
    18601 tcggaacctg atccgggtca tgccggcgaa gggagagtcg cagccttggt acgcacagag
    18661 acggatgtac tggtcgtcgg cggcgggatc atcggcctcg ccgtggcctg gcagacggcg
    18721 cagcgcggcc tctcggtggc ggtgctggac cccgaccccg gccatggggc cgcgcaggtc
    18781 gccgccggga tgctggcacc ggtcaccgag ttgcagtacg gcgaggagcc gctgctgcgg
    18841 ctgggcatgg cctccaatgc gcggtacgcg gccttcgccg ccgagctgga ggaggtgtcc
    18901 gggctctcca ccggctaccg cgcctgcggc accctcgcgg tggcgctgga ctccgacgac
    18961 cgggcggagc tgctggagct gtacgccttc caccagcggc tcggcctgga ctcgacctgg
    19021 ctgaccggcc gcgaggcccg ccggctggag ccgatgctgg cgccgtccgt acgcggcggc
    19081 ctgcatgtgg ccgaggacca ccaggtggac ggccgccggg tgggcgccgc cctggtggcg
    19141 gcgtgccgcc gggccggggt gcggctggtc ccggccgccg ccgcgcggct caccgtgcgg
    19201 tcggaccggg cgaccggggc ggtggccgac tccggtgagg agttcaccgc cgaccaggtg
    19261 gtgctggcgg cgggcagccg cagccatctg ctgccgggcc tgcccgacgg tgtgctgccg
    19321 ccggtgcgcc cggtgaaggg ccaggtggtg cggctgcggg tgccgccggt gtacgcgccg
    19381 ttcctctccc gcaatgtccg ggcggtggtg cgcggctgcc atatctacct ggtgccgcgc
    19441 gaggacggcg agctggtgat cggcgccacc accgaggagc tggggtacga caccacggtg
    19501 acggcgggcg gggtgtacga gctgctgcgc gacgcccatg agctgatccc cggcatcacc
    19561 gagctgccgc tggtggagac cggcgccggg ctgcgtcccg gctcgcccga caacgccccg
    19621 ctgctgggcc ccacggcgct gccgggcctg gtcgccgcca ccggccacca ccgcaacggg
    19681 gtgctgctga ccccggtcac cggcgacctg atcgccgagt acctggccac cggtcggctg
    19741 cccgagctgg ccgcaccctt cctgaccagc cgtttctccc gtaccccgac cctcgcccag
    19801 gaggtcctgc gatgaccgca ccgcaccccc cgcagatcgc cctctccgtg aacggcgagc
    19861 cgcgccgcgt ccccggcggc gccaccctcg ccgatgtggt ggcgaccctc agcagcgcgc
    19921 cctcgggggt ggccgccgcc gtcaacgagg ccgtggtgcc gcgcagcgcc tggggcgcca
    19981 cgccgctcgc ggaggacgac cggatcgaga tcctgaccgc ggtccaggga ggctgaacca
    20041 tggcggacga cgttctcacc atcgccggga cggccttcac ctcccggctg atcatgggta
    20101 ccggcggtgc tcccagcctg gaggtgctgg agcaggcgct gcgggtgtcc ggtacggagc
    20161 tgaccacggt ggcgatgcgc cgggtcgacc cgaccgtcaa ggggtcggtg ctggaggtgc
    20221 tggcccgcaa ctccatccgg gtgctgccca acacggcggg ctgcttcacg gcgggcgagg
    20281 cggtgctgac cgcccggctg gcccgggagg cgctgggcac cgactgggtg aagctggagg
    20341 tggtcgcgga cgagcgcacc ctgctgccgg acccggtgga gctgctggag gcggcggaga
    20401 cgctggtgga cgacggcttc acggtgctgc cgtacaccag tgacgacccg gtgctggcgc
    20461 ggcggctgga ggaggtgggc tgcgcggcgg tgatgccgct gggttcgccg atcggctccg
    20521 ggctgggcat ccgcaatccg cacaacttcc agctgatcgt ggagaacgcc ggggtgccgg
    20581 tggtgctgga cgcgggcgcg ggcaccgcct cggacgccgc cttcgcgatg gagctgggct
    20641 gcgacgcggt gatgctggcc tccgccgtca cccgtgccca ggacccggcg ctgatggccg
    20701 acgcgatgcg gcgggcggtg gaggcggggc ggctggcccg gcgggcgggg cgcattccgc
    20761 gccggttcca cgccgaggcg tcgtcgccgc ttgcgggccg ggccgagctg gaccaccggg
    20821 agatgcccgc cttccagacg ttctgaggtc agcaagcgtt ctgaggtcag tacgcatggt
    20881 cggccgtgac gtccgccgac agctccaggg cccgttcggc gtcggcgccg cgcagcgcca
    20941 gcagggtcag ggtcagggcg tcgatcgcgg cgaggtgggc gagtcggctg gcgacggtct
    21001 ccagcccgaa gacgaggtcc tggccaccgg cgaccaatgt ccagctgctg gtctcgctca
    21061 gcggtgagtg ggcgtagctg gtcacggcga tgacgcccgc ccctgccgcg cgcgcccggc
    21121 gggcggcgtc g
//
