LOCUS       NZ_QJSP01000011        29219 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Williamsia limnetica strain DSM 45521 Ga0244495_111, whole genome
            shotgun sequence.
ACCESSION   NZ_QJSP01000011
VERSION     NZ_QJSP01000011.1
KEYWORDS    WGS; RefSeq.
SOURCE      Williamsia limnetica
  ORGANISM  Williamsia limnetica
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Williamsia.
REFERENCE   1  (bases 1 to 264313)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 264313)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JUN-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Expected Final Version            :: No
            Genome Coverage                   :: 169.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003217475.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 01:29:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,026
            CDSs (total)                      :: 5,970
            Genes (coding)                    :: 5,910
            CDSs (with protein)               :: 5,910
            Genes (RNA)                       :: 56
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3 (5S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 17 of 60
            Pseudo Genes (incomplete)         :: 43 of 60
            Pseudo Genes (internal stop)      :: 7 of 60
            Pseudo Genes (multiple problems)  :: 7 of 60
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:55:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 88650
            Orig. end                         :: 117869
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QJSP01000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..29219
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..29219
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29219
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:19219](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..19219)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    265..280
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     misc_feature    322..335
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            complement(984..1802)
                     /locus_tag="DFR67_RS18780"
                     /old_locus_tag="DFR67_11186"
     CDS             complement(984..1802)
                     /NRPS_PKS="Domain: PKS_KR (20-185). E-value: 4.9e-09.
                     Score: 28.3. Matches aSDomain:
                     nrpspksdomains_DFR67_RS18780_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014925476.1"
                     /locus_tag="DFR67_RS18780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_11186"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_110471027.1"
                     /sec_met_domain="adh_short_C2 (E-value: 6.7e-39, bitscore:
                     128.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAVNPAAPAGNSGLLADKVVVVGGVGPGLGRSIALQAAAAGAK
                     VVLAARTASRLEDIAKEIQAAGGTSLQVPTDITDDAAVQALVERSVAEFGHVDVLVNNA
                     FSLPSMKPLARTDFDHIRSSLDLTVLGGLRMTKAFTDELEKSSGAIVMINSMVVRHSEP
                     RYGSYKLSKAALLAMSQTLATELGEKGIRINTVAPGYIWDDQLKWYFGEVAKKYGITPE
                     QVYEQTASKSDLKRLPEPDEIARAAVFLASDWASAITGQTLDVNCGEYHV"
     aSDomain        complement(1248..1742)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DFR67_RS18780_PKS_KR.1"
                     /evalue="4.90E-09"
                     /label="DFR67_RS18780_PKS_KR.1"
                     /locus_tag="DFR67_RS18780"
                     /protein_end="185"
                     /protein_start="20"
                     /score="28.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVVGGVGPGLGRSIALQAAAAGAKVVLAARTASRLEDIAKEIQA
                     AGGTSLQVPTDITDDAAVQALVERSVAEFGHVDVLVNNAFSLPSMKPLARTDFDHIRSS
                     LDLTVLGGLRMTKAFTDELEKSSGAIVMINSMVVRHSEPRYGSYKLSKAALLAMSQTLA
                     TE"
     CDS_motif       complement(1650..1739)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DFR67_RS18780_0001"
                     /evalue="5.30E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="DFR67_RS18780"
                     /protein_end="51"
                     /protein_start="21"
                     /score="9.5"
                     /tool="antismash"
                     /translation="VVVGGVGPGLGRSIALQAAAAGAKVVLAAR"
     gene            complement(1799..3004)
                     /locus_tag="DFR67_RS18785"
                     /old_locus_tag="DFR67_11187"
     CDS             complement(1799..3004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928338.1"
                     /locus_tag="DFR67_RS18785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_11187"
                     /product="hypothetical protein"
                     /protein_id="WP_110471028.1"
                     /transl_table=11
                     /translation="MTTPVTTEVAAAPDVTAPFAAAVAEAEKLIASADFIRNDDDLAEG
                     YDYLAGSIRASLQMAWAYDKSHPFFVTSTGPYTKMGLDNPDTLYYHANVEADAEYVITG
                     TRGTTADLSFQVLKGDYTATDVPGGDDAFDDRRLDIEPDGSFTLRFGPPKDDPGPNYFV
                     LGEGSSMLAVREVYGDWSAQKGQIRIERVDTVGTAPEEAGLAQITRRYHVAGKMLLSRI
                     NTWFNFPKWFYLDLPVNTLTAPRLTPGGLSTQFSSVGHYDLADHEAMVITVPKSDAPYQ
                     GFQLGSMWYISLDYVNHQTSLNTAQAQVDPDGMIRLVVSKQNPGIANWIETTGKQRGIA
                     QFRWQRVSRTLTESDGPSVEIIDVGDVAAHLPYHDTNTIDEAGWRERIALRQRGFAQRM
                     LG"
     gene            complement(3036..3608)
                     /gene="hsaB"
                     /locus_tag="DFR67_RS18790"
                     /old_locus_tag="DFR67_11188"
     CDS             complement(3036..3608)
                     /EC_number="1.5.1.36"
                     /GO_function="GO:0036382 - flavin reductase (NADH) activity
                     [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /GO_process="GO:0019439 - aromatic compound catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="hsaB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007240230.1"
                     /locus_tag="DFR67_RS18790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_11188"
                     /product="3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,
                     17-dione monooxygenase reductase subunit"
                     /protein_id="WP_110471029.1"
                     /transl_table=11
                     /translation="MVSYPLGTDDFDGRQFRTAMGQFCTGVTVITTVAPDDTPVGFACQ
                     SFAALSLDPPLVLFCPMKTSRSWKVIEQSKKFCVNVLSNNQQNVSAAFGAPGDDKFAGI
                     DWDPSPLGLPVIKHSLSWVDCTLERVDDGGDHFIVIGRVQTLGEVLQDKPLLFYRGGYL
                     STEHPHVTPAQAELENFLTWTGGDTWL"
     gene            complement(3612..4532)
                     /gene="hsaC"
                     /gene_synonym="bphC"
                     /locus_tag="DFR67_RS18795"
                     /old_locus_tag="DFR67_11189"
     CDS             complement(3612..4532)
                     /EC_number="1.13.11.25"
                     /GO_function="GO:0047071 -
                     3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,
                     17-dione 4,5-dioxygenase activity [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /GO_process="GO:0019439 - aromatic compound catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="hsaC"
                     /gene_synonym="bphC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020105090.1"
                     /locus_tag="DFR67_RS18795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_11189"
                     /product="iron-dependent extradiol dioxygenase HsaC"
                     /protein_id="WP_110471030.1"
                     /transl_table=11
                     /translation="MTEALGPIRSLGYMRIDATDMAAWREFGLKVLGMSEGSGPTDNAL
                     YLRMDEFPARLVIVPSDRDHLASSGWECANAAALQEVRDRLSAAGVIFREGKDEELEDR
                     QVVEMVVFEDPSGNVLEAFHGVALQHRRVVSPYGHTFVTGEQGLGHVVLTTDDDAASLR
                     FYRDVLGFRLRDSMRLPPEMVGREKGDEPPWLRFFGCNPRHHSLAFLPFPNETGIVHLM
                     IEVENTDDVGLAHDRALRKKVPMSATLGRHVNDLMYSFYMKTPGGFDVEFGCEGRQVDD
                     HEWIARESTAVSLWGHDFSIGFKNA"
     gene            complement(4613..5794)
                     /gene="hsaA"
                     /locus_tag="DFR67_RS18800"
                     /old_locus_tag="DFR67_11190"
     CDS             complement(4613..5794)
                     /EC_number="1.14.14.12"
                     /GO_function="GO:0036383 -
                     3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione
                     monooxygenase activity [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /GO_process="GO:0019439 - aromatic compound catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="hsaA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020105091.1"
                     /locus_tag="DFR67_RS18800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_11190"
                     /product="3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,
                     17-dione monooxygenase oxygenase subunit"
                     /protein_id="WP_110471031.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.2e-08, bitscore:
                     29.6, seeds: 790, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRSQAGAEVLEKISALLPEIEQRAQECEDLRQIPDETIASLAD
                     VGFFRLLQPEQWGGYQVDPVTFYEAVRRIGSACGSTGWVSSIIGVHNWHLALFPQQAQE
                     DVWGEDTSVRISSSYAPMGMGEVVDGGYKVNGSWAWSSGCGHAEWVVLGGPVIKNGKPV
                     DFVSFLIPRSDYTIRDVWHVVGLKGTGSNTIDVKDVFVPSHRMLSFRAMSTGTAPGLEK
                     NTAPVYKMPWGSVHPSVISAPIVGMAYGAYAAHVEHQGKRVRAAYAGEKAKDDPFAKVR
                     IAEAASDIDAAWTQLSGNLQSEYDLLVAGEEVPMELRLKARRDQVRATGRAVASIDRLF
                     ENSGAHALDSDTPIQRFWRDAHAGRVHAANDAERAYVAFGNGEFGIPIGDTMV"
     misc_feature    complement(5920..5936)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 20.13"
                     /tool="antismash"
     misc_feature    5920..5936
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.3"
                     /tool="antismash"
     gene            6045..7229
                     /locus_tag="DFR67_RS18805"
                     /old_locus_tag="DFR67_11191"
     CDS             6045..7229
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006358448.1"
                     /locus_tag="DFR67_RS18805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_11191"
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_110471032.1"
                     /transl_table=11
                     /translation="MVETKAKAGIDNSADGGAVREIDTGTPPTRFARGWHCLGLLSDYD
                     DGKPHSVTVFGTKLVVWVAEGELKILDAYCRHMGGDLSQGSIKDGNIACPFHDWRWKAN
                     GRCAGVPYAKRAPKLAKTRPWPGMIRNGQVFVYNDPEGNPPPDDVVIPELDELNSDQWT
                     GWTWNTIVIEGSNCREIIDNVVDMAHFFYVHYSLPDYFKNVFEGETAAQYMNSHGRPDV
                     DIMTAYGDTKLESIAAYYGPAYMLNPMVQYYGGYAIETILTNCHYPIDNNSFVLMYGVI
                     AKIPEGLTADQADKMATKITAGIEVGFLQDVEIWKHKSRIDNPLLVEEDGPVYQLRRWY
                     EQFYVDVADVTEEMTQRYEYEIDTTKAVENWNLEVQENIRLKAERADAEKAAAT"
     gene            7229..7588
                     /locus_tag="DFR67_RS18810"
                     /old_locus_tag="DFR67_11192"
     CDS             7229..7588
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020105093.1"
                     /locus_tag="DFR67_RS18810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_11192"
                     /product="hypothetical protein"
                     /protein_id="WP_110471033.1"
                     /transl_table=11
                     /translation="MTVSWSKAPDFTADPERKAAVQEATTRDKEHYLRGGLTEIECRAC
                     HACVMVKKYSPHHTSVQWTSAARDNCPEFKAIRAEGGNPAMLPTCPRMSASIDHGVSEG
                     IIPKESPDVDPDGYY"
     gene            complement(7713..8660)
                     /locus_tag="DFR67_RS30945"
                     /old_locus_tag="DFR67_11193"
     CDS             complement(7713..8660)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DFR67_RS30945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DFR67_11193"
                     /product="hypothetical protein"
                     /protein_id="WP_211325110.1"
                     /transl_table=11
                     /translation="MTYGPPPGNFPPPGGQPGGYPSGAHGQPAGGHPGGGYQPGGYQQP
                     PQSGFGAAPGGRRSPAGGLLAPTSSNSLLKFTGIAVAVGGLLMMLFSFFSWAADDNELA
                     SVSISGMGSVSVDGSGSDEIAQLLEDSGKSPGIFTVILGVLIIAAAVPLIINKFPGIGA
                     IAATVLGFIAIILALVYLFGPAGAVLEDAGDSDISDAGFGLWLVTIGALAALIAGGLSV
                     FFALTSPPGRPTGNQTPQGYGPPAGQGFGQQPGQGYGQQPGQGYGQQPGQGFGQQPGQG
                     YGQQPGQGYGQQQPGYGQPGGYPPQQPGPYGPQR"
     gene            complement(8742..9911)
                     /locus_tag="DFR67_RS18820"
                     /old_locus_tag="DFR67_11194"
     CDS             complement(8742..9911)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DFR67_RS18820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DFR67_11194"
                     /product="hypothetical protein"
                     /protein_id="WP_146240478.1"
                     /transl_table=11
                     /translation="MTYDRSRVDPGDWQSAGAPSGRRPRTVPAAENAGRRSTSGGGLFA
                     ASSGDSRLRFAGLVLAAAGVLIVVCSFLTWASASDDELSLSVTGMGSVSFEASEARAQA
                     LGGSADVAAELDERGKAPGVFTALFGALLAGAAILMVINRYPGLGAAAGAVLALIAVFM
                     SLEYLFAPGDAVLDGTGSTGIGYAGVGLWLVTLGAFVALAASGFGTITALRGRRRPLTE
                     SAAPRRRAESGARPSTQRRSAGETARDRSAEPVRGGPGQREFEPRYRDRPAPTVPPSPP
                     RPDFRPQPGYRARQGGGDGSMGRRPPPATPGYRPTPPPRPLPNSYPTVNQPVGDRDRPP
                     RAVPPGPVSPGRRQTGPIPPGGDGPPGQQRPPSRRAPAPRHTVQDEDGR"
     gene            complement(10001..11077)
                     /gene="dmpG"
                     /locus_tag="DFR67_RS18825"
                     /old_locus_tag="DFR67_11195"
     CDS             complement(10001..11077)
                     /EC_number="4.1.3.39"
                     /GO_function="GO:0008701 - 4-hydroxy-2-oxovalerate aldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="dmpG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014361386.1"
                     /locus_tag="DFR67_RS18825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_11195"
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="WP_110471035.1"
                     /sec_met_domain="HMGL-like (E-value: 3.1e-51, bitscore:
                     168.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFANSTDLMAGARKYSDALHIRITDSSLRDGSHHKRHQFTEQEVR
                     DIVGALDGAGVPVIEVTHGDGLGGSSFNYGFSKTPEQQLIKAAVETATTAKIAFLMLPG
                     LGVKDDIRAAQDGGAQICRIATHCTEADVSIQHFGLARELGLETVGFLMMSHSQPPEVL
                     ARQARIMADAGCQCVYVVDSAGALVLEQVSDRVAALKDELGDDAQIGFHGHENLDIAVA
                     NSIAAVRAGAQQIDGSVRRFGAGAGNTPVEAFVGVCDKLGISTGVDFMKIADAAQDVVR
                     PVMPSECLVDRPAMMMGYAGCYSSFLKHAEGHAEKYGVSAAEILLEAGARKLVGGQEDQ
                     LIDIALELKKKQDANAGV"
     gene            complement(11079..11990)
                     /locus_tag="DFR67_RS18830"
                     /old_locus_tag="DFR67_11196"
     CDS             complement(11079..11990)
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0008774 - acetaldehyde dehydrogenase
                     (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020105097.1"
                     /locus_tag="DFR67_RS18830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_11196"
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="WP_110471036.1"
                     /transl_table=11
                     /translation="MAGKVTAAIIGSGNIGTDLMYKLARSEVIEPRWMVGIDADSEGMK
                     RAADRGLITMSGGADELLASEEKPDLIFEATSAYVHREYAPKYEAAGITAIDLTPAAVG
                     PAVVPPANLREHLDAPNTNMITCGGQATIPMVHAVSSVVPVAYAEIVASVSSKSAGPGT
                     RANIDEFTKTTSRGVETIGGADRGKAIIILNPADPPMIMRDTIFCAIPEDADIDAIAEA
                     IHRREKEIQQYVPGYRLLQDPQFDPPSVGNGGMARVSIFVEVEGAGDFLPPYAGNLDIM
                     TAAATKVGEEIAKQKLAAKVGV"
     misc_feature    complement(12027..12041)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.67"
                     /tool="antismash"
     gene            complement(12046..12834)
                     /locus_tag="DFR67_RS18835"
                     /old_locus_tag="DFR67_11197"
     CDS             complement(12046..12834)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020105098.1"
                     /locus_tag="DFR67_RS18835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_11197"
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="WP_110471037.1"
                     /transl_table=11
                     /translation="MTITDQQRHQIADELARAEASAVAIDPPVVAYPDIDVTDAYEIQL
                     INIRRRLDAGARVAGHKVGLASEAMQKMMGVDEPDYGHLLDVMQYHEHTPIDATKFCFP
                     RVEVEVGFILGADLPGAGCTNEDVIAAVEWVVPSIELIDSRIRDWKISLPDTIADNASS
                     CGWVLGEQRVKISDIDTGDIDATLHRNGELIAEGNSSAVLGHPLTAVSWLARKVESFGV
                     RLRKGDVILPGTATRAIDIRSGDHFVADFVGLGSVTLDFT"
     misc_feature    12825..12839
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            13023..14759
                     /gene="kstD"
                     /locus_tag="DFR67_RS18840"
                     /old_locus_tag="DFR67_11198"
     CDS             13023..14759
                     /EC_number="1.3.99.4"
                     /GO_function="GO:0047571 - 3-oxosteroid 1-dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006694 - steroid biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="kstD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007624609.1"
                     /locus_tag="DFR67_RS18840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_11198"
                     /product="3-oxosteroid 1-dehydrogenase"
                     /protein_id="WP_110471038.1"
                     /sec_met_domain="DAO (E-value: 5.3e-16, bitscore: 53.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSDQTGSGPTSVDETFDVIVVGAGGAGMSTAITAAAHGLDTVI
                     VEKSAYWGGSTSRSGGGVWIPNNKVLQRDGVKDDPEAARTYVRSIVGDGVAPERIDAYI
                     DRGPEALAFLSENSPLELEWVKNYSDYYPEAPGGRVGGRSCEPKPFDSRKLGDDIKTLH
                     PPYSKAPLNVVVMQSDYRWLSTGLRHWKGPLRAAKVGSRFIWAKLTRKKLIAMGAALMS
                     ELLLGVRQAGVPLRLNTPLVDLVTEGGRVVGIVVESDGKTKTLRARQGVVLACGGFEHN
                     DEMRHKYQREPIGSQWTTGAESNTGDGINAGLKIGAGVSYMEDAWWGPTIPLPRGPWFA
                     LSERALPGSFMINDRGQRFMNESLPYVEAVHQMYGGEFGQGEGPGENLPCWLVFDQTYR
                     NRYMFASVSGRQPLPGKWFKSGVITKSETLSGLAEKIGVPAEGLTQTAERFNAFAAAGK
                     DEDFGRGVSRYDHYYGDITNKPNPSLGPLKKGPFYAVKMVPGDLGTKGGINTDAAGRAL
                     RADGSVIEGLYAAGNTSSPVMGHTYAGPGATIGPAMVFGYLAALDIATNAQSSRATEEK
                     AG"
     gene            14759..15619
                     /locus_tag="DFR67_RS18845"
                     /old_locus_tag="DFR67_11199"
     CDS             14759..15619
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018178297.1"
                     /locus_tag="DFR67_RS18845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_11199"
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="WP_110471039.1"
                     /transl_table=11
                     /translation="MPIDPDVALGAVVAKETFSWSASDVALYNLAVGAGSDPLNATALE
                     YLDDRRPKVLSSFATVAAHFHETEPPKVSKPGIEIDLGSVVHGAQEVQVHKPIPAMGTA
                     TTTTTVVELQDKGSAAVIIEESVTVDDGGEPLWTARSSIFCKGAGGFGGERGTSDKVNY
                     PDREPDHVIEEKTLPQQALLYRLCGDRNPLHSDPAFAEKAGFPRPILHGLGTYGIVLRT
                     VVDELLGGDVDRVASFGAKFAGVVFPGETLRIKVWDDDSRLLITASVVERDDSPALGNV
                     VLTKR"
     gene            complement(15634..15759)
                     /locus_tag="DFR67_RS31395"
                     /old_locus_tag="DFR67_111100"
     CDS             complement(15634..15759)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DFR67_RS31395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DFR67_111100"
                     /product="hypothetical protein"
                     /protein_id="WP_281268349.1"
                     /transl_table=11
                     /translation="MATSQVNDVSAVKLRLWRVLTMLASLVAVIVGLVAIFMSAA"
     misc_feature    complement(15835..15850)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.36"
                     /tool="antismash"
     misc_feature    complement(15888..15903)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
     misc_feature    complement(15890..15903)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.93"
                     /tool="antismash"
     misc_feature    complement(15891..15902)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.49"
                     /tool="antismash"
     gene            15952..17589
                     /locus_tag="DFR67_RS18855"
                     /old_locus_tag="DFR67_111101"
     CDS             15952..17589
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020105102.1"
                     /locus_tag="DFR67_RS18855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_111101"
                     /product="MFS transporter"
                     /protein_id="WP_110471041.1"
                     /transl_table=11
                     /translation="MKSTVGASPDERIGLRTVWLIFVACVAVSMVIAAMASLNTAIPDI
                     APAVQANSNQVTWLIDGYTLTLAALLLPAGAIGDRFGRREVLIAGLIVFAIGSLLPIWV
                     SDPTQFIAARCLTGVGAAFVMPATLSLITSGVPASKRPLAVSIWAGVAGAGGIAGFFVT
                     GVLLEFFSWHSIFLTFAIAAAVTAVLSCTIPTSRDSTSPKFDVWGSVTSALAVALVVFA
                     FIESPHRGWFDPLTVTAFVVGIGLAAVFWYSQSRRAEPLLDVKLFGNSAFAAGSFSVMI
                     QFMVAFGLFLVLLQYLQLVFGYSPLKSAIALFPMVIVVMVCSLIGNWIAVKVNLRIILS
                     AGMLVMGVGVILLGVIAHSEYWTVAVCLVVFALGLGIATAPSTTAIMVNTPADNQGVGS
                     AINDTSRELGSAIGIAIAGSLLASGYTRDVNATADAAQAQLRQTASQLESAGQVGRAQE
                     VAAAADGIKEHITNTLAEALQVAERLAPEQPELATRIAEGAKDAFIGPMNAASITLGAL
                     SIAAGVILAIFTPNRMDSDVEPEKLSDR"
     gene            complement(17597..19219)
                     /locus_tag="DFR67_RS18860"
                     /old_locus_tag="DFR67_111102"
     CDS             complement(17597..19219)
                     /NRPS_PKS="Domain: AMP-binding (8-437). E-value: 1.9e-60.
                     Score: 196.5. Matches aSDomain:
                     nrpspksdomains_DFR67_RS18860_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020105108.1"
                     /locus_tag="DFR67_RS18860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_111102"
                     /product="AMP-binding protein"
                     /protein_id="WP_110471042.1"
                     /sec_met_domain="AMP-binding (E-value: 3.4e-63, bitscore:
                     207.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFNLADVFETVADSVPDTIALTYEGVDHSYRQLEVEANQVAHML
                     TAAEVAAGEHVALFLKNSVEHVTTILGVIKIRAVPININYRYTPAELLYIFENSDSVAI
                     VVEEAEHQDNLAQIVGEIPTLRTIFVIGDITEGLSAAAADAGVRVRPFDASDQSEARNF
                     EPRTGDELWVLYTGGTTGYPKGVMWRHDDFFHKPLSGGNPYDENPRKDLAEVGAAAKEF
                     PGLSFLIAAPLMHGAALYSLFTFLTLGARLVLMRAFDPEKVVRSIETDKVNVVLIVGDG
                     MGSPLADAMEKLKDEVDLSTLFSITSGGAVWSVGVRERMLAVKPDLVLRDNFGASETGN
                     DGAFEVRDDGTLAMPPTAKMTVLDEKLNVIPAGSGDVGMIARIGRVPLGYYRDEEKSAR
                     TFPQLPDGTRVAVLGDMGLVEADGTIVFLGRGSQCINTGGEKVYAEEVEACLHAHPAVA
                     DALVVPSPDERMGQKVSAVVAIRPGIAEPSLDEIQSHCRTMLAGYKIPRLLVIVDEIKR
                     TPAGKADYKWAKQAALDLAGTTV"
     aSDomain        complement(17909..19195)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DFR67_RS18860_AMP-binding.1"
                     /evalue="1.90E-60"
                     /label="DFR67_RS18860_AMP-binding.1"
                     /locus_tag="DFR67_RS18860"
                     /protein_end="437"
                     /protein_start="8"
                     /score="196.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FETVADSVPDTIALTYEGVDHSYRQLEVEANQVAHMLTAAEVAAG
                     EHVALFLKNSVEHVTTILGVIKIRAVPININYRYTPAELLYIFENSDSVAIVVEEAEHQ
                     DNLAQIVGEIPTLRTIFVIGDITEGLSAAAADAGVRVRPFDASDQSEARNFEPRTGDEL
                     WVLYTGGTTGYPKGVMWRHDDFFHKPLSGGNPYDENPRKDLAEVGAAAKEFPGLSFLIA
                     APLMHGAALYSLFTFLTLGARLVLMRAFDPEKVVRSIETDKVNVVLIVGDGMGSPLADA
                     MEKLKDEVDLSTLFSITSGGAVWSVGVRERMLAVKPDLVLRDNFGASETGNDGAFEVRD
                     DGTLAMPPTAKMTVLDEKLNVIPAGSGDVGMIARIGRVPLGYYRDEEKSARTFPQLPDG
                     TRVAVLGDMGLVEADGTIVFLGRGSQCINT"
     CDS_motif       complement(18650..18703)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DFR67_RS18860_0001"
                     /evalue="4.20E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="DFR67_RS18860"
                     /protein_end="190"
                     /protein_start="172"
                     /score="19.4"
                     /tool="antismash"
                     /translation="VLYTGGTTGYPKGVMWRH"
     gene            complement(19231..20403)
                     /locus_tag="DFR67_RS18865"
                     /old_locus_tag="DFR67_111103"
     CDS             complement(19231..20403)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006865446.1"
                     /locus_tag="DFR67_RS18865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_111103"
                     /product="lipid-transfer protein"
                     /protein_id="WP_110471043.1"
                     /transl_table=11
                     /translation="MSGLSGKAAIAGIGATDFSKNSGRSELRLAAEAVTAAIADAGLTP
                     ADVDGLVSFTMDTNTEIAVARASGIGELTYFSRIHYGGGAACSTVQQAAMAVATGVADV
                     VVAYRAFNERSGMRFGQVNTSLVAQDNSSGTDNAFSYPHGLSTPAAFVAMVAQRYMHEY
                     GATSEDFGRISVVDRKHAAVNPEAFFYGKPITLEDHQNSRYIAEPLHLLDCCQESDGGV
                     AFVIVSAERAKDLPHTPAIIAGAASGSGDDQYIMTSYYRDDLAGLPEMGLVGRQLWEQS
                     DLGPEDVDLAILYDHFTPYTLMQLEELGFCGRGEAKDFVREPGALEVGGRLPLNTHGGQ
                     LGEAYIHGMNGIAEAVRQLRGKSVNQVPGARKVVVTAGTGVPTSGLVLTA"
     gene            complement(20400..20858)
                     /locus_tag="DFR67_RS18870"
                     /old_locus_tag="DFR67_111104"
     CDS             complement(20400..20858)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018178286.1"
                     /locus_tag="DFR67_RS18870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_111104"
                     /product="MaoC family dehydratase"
                     /protein_id="WP_110471044.1"
                     /transl_table=11
                     /translation="MTVPATPPQAAVGTELPQLTVTATPTFVVSTALATRDFQDVHHDR
                     DLAHSKGSKDIFVNILTDTGLVQRYITDWAGQRAQIRSIKLRLGVPWYAYDTLTLSGTV
                     SSVEGDLVTVDVIGKDGLGNHVTSVVTLVMDHTTAAVSGSTSEAGVAQ"
     gene            complement(20855..21868)
                     /locus_tag="DFR67_RS18875"
                     /old_locus_tag="DFR67_111105"
     CDS             complement(20855..21868)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012832778.1"
                     /locus_tag="DFR67_RS18875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_111105"
                     /product="OB-fold domain-containing protein"
                     /protein_id="WP_110471045.1"
                     /transl_table=11
                     /translation="MSDTTTAILAATDEVRDAGTSAPLAGRDPVNTPMINNWVEAIGDT
                     NPIYVDPGAARAAGYDDVVAPPAMAQVWTMRGLNGVRAEDDPLGQVTEILDAAGYSSVV
                     ATNCDSTYHRYTVPGEHVTIESALTDVVGPKQTALGEGWFFTTKNIWKVGDEVVAEMDF
                     RILKFRPAEKAAITEPAGGEVISSLGAATADVDPAKMMRPTPSLDTLFFWNGVREHELR
                     IQKVDDGTLRHPPIPALWKPRGEDTDYVVSSGRGTVYSYVVHHAPKVPGRTLPFVVALV
                     ELDEGVRLLGELRGIEPAQVTVGLPVQVEFLDFPADSAAQTEAWTLYAWQPAGELS"
     gene            complement(21865..23028)
                     /locus_tag="DFR67_RS18880"
                     /old_locus_tag="DFR67_111106"
     CDS             complement(21865..23028)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010842154.1"
                     /locus_tag="DFR67_RS18880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_111106"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_110471046.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.3e-26, bitscore:
                     85.3, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.2e-21, bitscore:
                     69.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 7.7e-23, bitscore:
                     75.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIDLTDEQRSLKMELREYFSNLVSPEDATTMLTERHGPTYRKVI
                     RQMGSDGWLGVGWPKEYGGRGFGQIEQQIFVNEAARADIPLPAVTLQTVGPTLQAYGTD
                     EQKQRFLPDILAGEVHFAIGYTEPDAGTDLASLKTSAVLQGDEYIVNGQKIFTTGGHDA
                     DYVWLAVRTDKDVAKHKGISMLIVDTKDPGYSWTPIITADRAHHVNATYYSDVRVPAGM
                     VVGEVNGGWRLITTQLNHERVMLGPAGRLDGLLARITDWANRPGPDGTVPGKHTDVRRA
                     LAELHAYYRINELLNWQVASGGDSISMADAAATKVFATERLQHVHRLIDEILGRHGDFS
                     DPATAELADWFDVQAKRNVVITFGGGVNEVMREMIATAGLGLPRGKR"
     gene            complement(23031..24089)
                     /locus_tag="DFR67_RS18885"
                     /old_locus_tag="DFR67_111107"
     CDS             complement(23031..24089)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020105113.1"
                     /locus_tag="DFR67_RS18885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_111107"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_110471047.1"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.2e-15, bitscore:
                     50.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTRDSTAETVSDVIDSVLQRHESIWDAGLTDVGGFETSLWAAL
                     AESGLLALPLPEASGGDDVAVGGLVPIPTALGRAAAVTPAIGTLIAGLAPLAHRAPDVA
                     ATLGARVQAGGWLATAISEPGAALTDTPHTTISNGKLSGTKTGVLHAEGASAILVSTDA
                     GVAVVPADAPGVRMTRTTSSSGWGEYTVVLTDVAADSVIDGDPGWLQQHHSLGIAAYAD
                     GLVAGAMKLTATHVSERVQFDKPIGTFQAVQQQLADIYVVARSMTLATTSAGWRLTEGL
                     DAGTDLALSGYWLAQEIPATMRTMIHLHGGVGVDLTYPLHRYFSIAKDLARLVGGPTGR
                     LDALAQQVEAGV"
     gene            complement(24149..26407)
                     /locus_tag="DFR67_RS18890"
                     /old_locus_tag="DFR67_111108"
     CDS             complement(24149..26407)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020105114.1"
                     /locus_tag="DFR67_RS18890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_111108"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_110471048.1"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2e-20, bitscore:
                     67.5, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 5.9e-13, bitscore:
                     43.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.7e-21, bitscore:
                     69.6, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIATTPEHTAVADAIGQWSKKVSVITTVRAGEPGSDLTAEPWPA
                     LFRELAELGIFAAAVPEGKGGMDALFTDLAVMLEQTGYDLVPGPVAGTALSALLTSLSG
                     SPNENALLAQLIAGDVGAAVATSVLAGAVAPRAVDPERGRGEADPDHPKGVLSASGDLG
                     LVAGYAPDVALLAPIDIAGSHRWVLLEPGTSGIVSEPVEALDFSMALSRVRLDDVVIPA
                     HDVLHVSDAFVRATIIAVIAAQASGVARWTLDTAVEYAKVREQFGAPIGSFQAVKHICA
                     EMLCRSEQVSAAAWDLASAVDELTDADGPERAGAAEQVEISAAVAAAAVSEMVVANAKD
                     CIQILGGIGFTFEHDAHLYLRRALAWQAQLGSPGHWHAAIAELNRRGVRRKLRVDLSDA
                     EGQRREVRADAEAIAAAGDQRRALAETGYLTPHWPAPFGLGADAVRQVLIDEELERAGV
                     RRPDLVIAGWAIPTIIEHGTDRQRERFVKPTLDGEVMWCQLFSEPGAGSDLAALRTKAT
                     RVEGGWSLQGQKVWTSHAHDADWAICLARTDPDAPKHKGITYFLVDMTSSGIETRPLRE
                     ITGRAMFNEVFLDDVFVPDDCVVGEINNGWRLARTTLANERVAMGGSALGKEMEALLAQ
                     IDGGETGTERGELTGTQCEKLGELIAQAQLGQVLDLRSVLGSINGTDPGAASSVRKLIG
                     VRHRQAVPEFAQQLHGVAGLAQSTASQDFLLNRCLSIAGGTTQILATAAAERLLGLPR"
     misc_feature    complement(26454..26470)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.26"
                     /tool="antismash"
     gene            26614..27267
                     /gene="kstR"
                     /locus_tag="DFR67_RS18895"
                     /old_locus_tag="DFR67_111109"
     CDS             26614..27267
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="kstR"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010842157.1"
                     /locus_tag="DFR67_RS18895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DFR67_111109"
                     /product="cholesterol catabolism transcriptional regulator
                     KstR"
                     /protein_id="WP_110471049.1"
                     /transl_table=11
                     /translation="MASPIPAGNSASDVAVGSDVDLGSSAQRERRRRILDATLQLASKG
                     GYDAVQMRAVAERADVAVGTLYRYFPSKVHLLVTALAREFEAVESRADKTRLRGNTALE
                     RLRHVLDMITLAMQRDPLLTEAMTRAFMFADASASAEVDKVALIIDRLLANAMVEGEPT
                     ELDLKIARVVSDVWMSNLVQWLTRRASATDVTNRLELTITLLLAGRDQDPEVKD"
     misc_feature    complement(27540..27554)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 20.76"
                     /tool="antismash"
     misc_feature    27581..27595
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.0"
                     /tool="antismash"
     misc_feature    complement(27753..27767)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.82"
                     /tool="antismash"
ORIGIN
        1 tccaccgtcc ccatcggatc ggttcggaaa tccctgaagt cgacatcgat gaactgagcg
       61 gggtcgtact tggcccgagc tgtgttgaac gcgcgcaatc cccgcgacca cagttcgagc
      121 tgcgtcttcc cgatcagctc cccgttgaac acggtcgacc acccttcacc cgccgcctcg
      181 gcaaggctgc acatcgaagg aatgatcgtg gccggcggcc ggtgggtctg gatgatcagg
      241 gcgtcggggt agatggccat caactcgtcg agcgcgaaca gatgactcgg gttcttgagg
      301 atccagcgac gctcaggctg gttcaacccg atcaactgga ggttcttctt gtgccgggtg
      361 taggcgttgg tccagttctg ctgctgcagc cactgcgagt acgtcggaag gtacgacagc
      421 gactcatacg agatcgactt gaaggtctgg cggagcaact gccagcactc ctccacgtcg
      481 gacgcgctca tgtagtgcag ccccatgaac tccggattct cgacgtggtg ttgttcgagg
      541 ccaccctgga tctgttggaa aaccgggttc gactcccagg tgtccctcgg cggccggggt
      601 tgcgggaact cggccagcca catctcgagg ccctggtgtc ccggatcggc cgtcagcagg
      661 cgatgtaacg cagtggtgcc ggtgcgcggc agccccgtga cgaaaatcgg cctgtccaca
      721 ggggcagtcg cgtactcggg attggccttc cacgacgcct cactcaggag ccgggccacc
      781 agcgcgccgc gcaggaagta ccggttcatc ttgctgccga gctcggtcat ccccgcgtcc
      841 cgcacgtagg actccaacag cacgccgagc gcctcggtgt agtcgtcgac accgaagtcg
      901 tcgaggccac aggccttggt ggcggaggca tgcaggtctt cgaccgtgcc gacatcggtt
      961 ctggtggtca tgtggcgctc cttctagacg tggtattcgc cgcagttgac atcgagcgtc
     1021 tggcccgtga tcgcgctggc ccaatcagat gccaagaaca ctgccgcgcg ggcgatctca
     1081 tcgggctcgg gtaggcgttt gaggtcagac ttcgacgccg tctgctcgta cacctgctca
     1141 ggagtgatgc cgtatttctt ggcgacctcg ccgaaatacc atttcaactg gtcatcccag
     1201 atatagccgg gagcaacagt attgatgcga atccccttct cccccagctc tgtcgcaagt
     1261 gtctgcgaca tcgcgagcag cgcagccttg gacaacttgt agctgccgta ccgcggttcg
     1321 gagtgccgca ccaccatcga gttgatcatc acgatggcgc ccgacgactt ctccagctca
     1381 tcggtgaagg ccttcgtcat ccggagcccg cccagcaccg tgaggtcgag gctcgagcga
     1441 atgtgatcga agtcggtgcg cgccagaggc ttcatcgagg gcaacgagaa tgcgttgttc
     1501 accagcacat cgacgtggcc gaactcggcg acgctgcgct cgaccaacgc ctggaccgcg
     1561 gcgtcgtcgg tgatgtcggt gggtacctgg agcgaggtgc caccggccgc ctgtatctcc
     1621 ttcgcgatgt cctcgagtcg ggacgccgtt ctcgccgcca gcaccacctt ggcaccggcc
     1681 gcggcggcct gcaaggcgat cgatcgaccg agccccggcc cgacaccgcc cacgaccaca
     1741 accttgtccg cgagcaatcc cgagtttccc gcgggcgcgg ctgggttcac cgcggcggtc
     1801 atccgagcat cctctgtgcg aatccacgtt ggcgcagcgc gatccgctca cgccagccgg
     1861 cctcgtcgat ggtgttcgta tcgtgatacg gcaagtgcgc cgcgacgtcg ccgacatcga
     1921 tgatctcgac ggacggcccg tccgactcgg tgagcgttcg ggagaccctc tgccacctga
     1981 actgtgcgat gccccgctgt tttcccgtcg tctcgatcca gttcgcgatc ccgggattct
     2041 gtttgctgac gaccaaccgg atcatgccgt caggatccac ctgcgcctgc gcggtgttca
     2101 ggctcgtctg gtggttgacg tagtcgagcg agatgtacca catgctgccg agctgaaaac
     2161 cctgataggg cgcatcggat ttggggacgg tgatcaccat ggcctcgtga tcggcgaggt
     2221 cgtagtgacc caccgaggag aactgggtgc tgagtccacc cggggtcagc cgaggtgctg
     2281 tcagggtgtt caccggcaga tccagataga accacttggg gaagttgaac caggtgttga
     2341 tgcgcgacaa cagcatcttg cccgcgacgt gatagcgccg ggtgatctgc gccagtccgg
     2401 cttcctccgg agcggtgccg acagtgtcga cgcgctcgat gcgtatttgt cctttctgcg
     2461 cggaccagtc gccgtatacc tcccgcaccg caagcatcga cgacccctcg cccagcacga
     2521 agtagttcgg gcccggatca tccttgggtg gtccgaaccg gagggtgaac gatccgtctg
     2581 gttcgatgtc gagccggcgg tcgtcgaagg cgtcgtcgcc gcctggaaca tcggtcgccg
     2641 tgtagtcacc tttgaggacc tgaaaactca gatctgcggt ggtgccgcgg gttccggtga
     2701 tcacatactc ggcgtcggcc tcgacattgg cgtggtagta cagcgtgtca gggttgtcga
     2761 ggcccatctt ggtataaggc ccggtcgacg tcacgaagaa aggatggctc ttgtcgtacg
     2821 cccaggccat ctgcaaactg gcccggatgc tgccggcgag atagtcgtat ccctctgcga
     2881 gatcgtcgtc gttgcgtatg aaatccgccg aggcgatcag cttctcggcc tcggccacag
     2941 ccgccgcgaa cggcgctgtc acatcggggg cagctgcgac ttcagtggta acaggggttg
     3001 tcatctcgct cctcgttgaa cggctgaacg cactactaca gccaggtatc gccaccggtc
     3061 caggtcagga aattctcgag ttccgcctga gccggcgtga cgtgcgggtg ctcagtggac
     3121 aggtagccac cacggtagaa cagcaaaggc ttgtcctgca gcacttcccc caaagtctgc
     3181 acccttccga tcacgatgaa gtgatctccg ccgtcgtcga cgcgctcgag ggtgcagtcg
     3241 acccacgaca gcgagtgttt gatcaccggc aaacccagcg gcgaggggtc ccaatcgatt
     3301 ccggcgaact tgtcgtcacc gggcgcaccg aaggccgcac tcacgttctg ctggttgttg
     3361 gagagcacat tcacacagaa cttcttgctc tgctcgatga ccttccagct ccgggaggtc
     3421 ttcatcggac agaacaggac aagcggcgga tcgagcgaaa gcgcggcgaa cgactgacag
     3481 gcgaacccga ccggcgtgtc atccggcgcc accgtggtga tgaccgtgac gcctgtacag
     3541 aactggccca tcgcggtccg aaactgccga ccatcaaaat cgtctgtgcc cagcggatac
     3601 gagaccatat ctcaggcgtt cttgaatccg atggagaagt catgccccca cagactcacc
     3661 gcggtacttt ctctcgcgat ccattcatgg tcgtcgacct gcctaccctc gcaaccgaac
     3721 tcgacgtcga agccgccggg ggtcttcatg tagaacgagt acatcaggtc gttgacgtgc
     3781 ctgcccagag tggccgacat cggaactttt ttccgcaggg cgcgatcgtg cgcaagccct
     3841 acatcgtcgg tgttctccac ctcgatcatc aggtggacga tgcccgtctc gttcgggaaa
     3901 ggcaggaatg cgaggctgtg atgccgcggg ttgcagccaa agaagcgcaa ccatggtggc
     3961 tcgtcgcctt tttcacggcc gaccatctcc gggggaagac gcatcgaatc ccgaagccgg
     4021 aagcccagca catctcgata gaaccgcagc gacgcagcat cgtcgtccgt ggtcagtacc
     4081 acgtggccga gcccctgctc cccggtcacg aacgtgtggc cgtatggact gaccacccgg
     4141 cgatgctgca aggccacccc atgaaaggcc tcgagcacat tgccggatgg gtcctcgaac
     4201 accaccatct cgacgacctg acggtcttcg agttcttcgt ccttgccttc gcggaagatg
     4261 actcccgcag cggacaaacg atcccggact tcttgcaatg ccgcagcatt ggcgcattcc
     4321 cagcctgaac tcgcgagatg gtcgcgatcg ctcggcacga tcaccaagcg agccgggaac
     4381 tcgtccatcc tcagatagag cgcattgtcg gtgggacccg aaccctcgga cataccgaga
     4441 accttgagac cgaactcccg ccacgcggcc atgtcggtgg cgtcgatacg catatagcca
     4501 agagaacgaa tcgggcccag cgcttcagtc atcgtcgaac tactccttcg aaagtggtgg
     4561 cttctggtga gttccactcg ggctttgctc gcccgaaccc accaattccg ggtcagacca
     4621 tggtgtcgcc tatggggata ccgaactccc cgttgccgaa tgccacgtag gcacgctcgg
     4681 cgtcgtttgc cgcgtggacc cggcctgcat gggcatcacg ccagaaccgc tgaatcgggg
     4741 tatcgctgtc gagcgcatgc gcccccgagt tctcgaagag gcgatcgatc gacgccacgg
     4801 cgcggccggt ggcacggacc tggtcacgac gggccttgag acgcaactcc atcgggacct
     4861 cctcgccggc gaccagcagg tcgtactcgg actgcaggtt cccggagagc tgggtccagg
     4921 cagcgtcgat gtcgctcgcg gcctcggcga tacgcacctt cgcgaacggg tcgtccttcg
     4981 ccttctcgcc ggcgtaggcg gcacgcactc gcttgccctg atgctcgacg tgggccgcgt
     5041 aggctccgta ggccattccg acgatcggtg cggagatgac gctgggatgc accgagcccc
     5101 agggcatctt gtacaccggt gccgtgttct tctcgagccc cggcgccgta cccgtgctca
     5161 ttgcccggaa actgagcatc cggtggctgg gcacgaagac gtccttgacg tcgatggtgt
     5221 tcgagccggt gcccttgagc ccgaccacat gccacacatc gcggatcgtg tagtccgagc
     5281 gtgggatcag gaagctgacg aagtcgacgg gcttgccgtt cttgatgacc gggcccccga
     5341 ggacgaccca ctccgcgtga ccgcatcccg acgaccaggc ccatgacccg ttgaccttgt
     5401 acccgccgtc gaccacttcg cccataccca tcggggcgta tgaggacgag atacgcaccg
     5461 aggtgtcctc accccacacg tcctcttgtg cctgctgcgg gaagagcgcg aggtgccagt
     5521 tgtggacgcc gatgatgctg gagacccatc cggtggaacc acatgccgac ccgatgcgcc
     5581 gcacggcttc gtagaatgtc acgggatcga cctggtagcc gccccactgt tcgggctgca
     5641 ggagccgaaa gaacccgacg tcggcgagcg acgcgatcgt ctcgtccggg atctggcgca
     5701 ggtcttcgca ttcctgggcc cgctgttcga tctcaggtag caacgcgctg atcttttcca
     5761 acacctctgc gcccgcttgg ctgcgatcac tcatcgagca actcctcgct ctcgttccac
     5821 ttcttcgttc caagactaga acacgttctc atttatgtcg agtactgggg gtttacccca
     5881 caatctgccg caaaagtgcc gtttggctgg cgggaatcaa cgaaattttg taacatgttc
     5941 tagtaagcgg aggcgcttaa agagacgtag gcgtagctcg acccggacag caacgcggca
     6001 gatgcgcagc tcatcgcgac atcgccgaac atagggagca gaacatggtg gagacgaagg
     6061 caaaggcggg gatcgacaac agtgccgatg gcggcgctgt tcgcgaaatc gacaccggca
     6121 cgccgccgac ccgattcgcc cgcggatggc actgcctcgg tctgttgtcg gactacgacg
     6181 acggcaagcc gcactcggtc accgtcttcg ggaccaagct ggtggtgtgg gtggccgagg
     6241 gagaactgaa gatcctcgac gcctactgcc gacacatggg cggcgatctc tcgcaggggt
     6301 cgatcaagga cggcaacatc gcctgcccgt tccatgactg gcgctggaag gcaaacggcc
     6361 ggtgtgccgg cgtcccgtac gcgaagcgcg caccgaagct ggccaagacg cggccgtggc
     6421 ccggcatgat ccgcaacggg caggtcttcg tctacaacga ccccgagggc aacccgccgc
     6481 cggacgacgt cgtcatcccc gaactcgacg aattgaacag cgatcagtgg acggggtgga
     6541 cctggaacac catcgtcatc gagggttcca actgccgcga gatcatcgac aacgtcgtcg
     6601 acatggcgca cttcttctac gtgcactatt cgctgcccga ctacttcaag aacgtcttcg
     6661 aaggcgagac cgcggcgcag tacatgaact cgcacggccg cccggatgtc gacatcatga
     6721 ccgcgtacgg cgacaccaaa ctcgagtcga tcgccgccta ctacggtccg gcctacatgc
     6781 tgaacccgat ggtgcagtac tacggcggct acgcgatcga gaccatcctg accaactgcc
     6841 actacccgat cgacaacaac tcgttcgtgc tgatgtacgg cgtcatcgcc aagatccccg
     6901 agggtttgac cgcggaccag gcagacaaga tggccacgaa gatcaccgcg ggaatcgagg
     6961 tcggcttcct ccaggacgtc gagatctgga agcacaagag ccgcatcgac aatccgctgc
     7021 tggtcgagga agacggcccg gtgtatcagc tgcgccgctg gtacgaacag ttctatgtgg
     7081 acgtcgctga tgtcaccgaa gagatgacgc agcgctacga gtacgaaatc gacaccacca
     7141 aggccgtcga gaactggaac ctcgaggtcc aggagaacat ccggctcaag gccgaacgcg
     7201 ccgacgcgga aaaggccgcg gcgacctgat gacggtcagc tggtccaagg ccccggattt
     7261 caccgccgat ccggagcgga aggccgccgt ccaggaggcc acgacccggg acaaggagca
     7321 ctatctccgg ggcggtctga ccgagatcga atgccgggcc tgtcacgcct gcgtgatggt
     7381 gaagaaatac agcccgcacc acaccagcgt gcagtggacc tcggcggccc gcgacaattg
     7441 ccctgagttc aaggcgatcc gcgccgaagg gggcaacccc gcgatgcttc ccacctgccc
     7501 gagaatgtct gcgagcatcg atcacggggt gagcgagggg atcatcccca aagagtctcc
     7561 cgacgtcgac cccgacgggt actactgagt tccgcgagaa tctgctccac atacaggaat
     7621 ccgctccgct tccagtgcgc tggaagtgga gcggatttct gtaagtggag cggatttctg
     7681 taagtggagc ggatgtgggt cggtcaggac gactagcgtt gcgggccgta aggaccgggc
     7741 tgctggggcg ggtacccacc cggttggccg tacccgggct gctgctgacc gtaaccctgg
     7801 cccggctgct gaccatagcc ctgacccggc tgctgaccga agccctggcc cggctgctga
     7861 ccatagccct gacccggctg ctgaccgtaa ccctggcccg gctgctgacc gaagccctga
     7921 cccgcgggcg ggccgtaccc ctgaggagtc tgattgcccg tcggacgccc cggcggggag
     7981 gtcagcgcga agaacaccga caatccaccg gcgatcagcg cagccagtgc gccgatggtc
     8041 accaaccaga gcccgaaacc ggcatcggag atgtctgaat cgcccgcatc ctcgaggact
     8101 gcaccggccg gaccgaaaag atagaccaac gccaggatga tcgcgatgaa tccgagaacc
     8161 gtagcggcaa tggcgccgat acccgggaac ttgttgatga tcagtggcac tgcagccgcg
     8221 atgatcaaca cgcccaagat gacggtgaag attcccggtg atttaccgct gtcctccagc
     8281 aactgcgcga tctcgtcgct acctgaacca tcgacggaca ccgaacccat tcctgaaatc
     8341 gagacactgg cgagctcgtt gtcatcggcg gcccagctga agaagctgaa cagcatcatc
     8401 agcaagccgc cgaccgcgac cgcgataccg gtgaacttca gaagtgagtt cgacgacgtc
     8461 ggtgcgagca aaccgcccgc gggggatcgc ctgccacccg gtgctgcacc gaatcccgac
     8521 tgtgggggct gctgatatcc acccggctgg tagccacctc ccggatggcc gccggcgggc
     8581 tgaccgtgag cgccggacgg ataaccaccc ggctgaccgc cgggcggagg gaagttgccg
     8641 ggtggtgggc cgtacgtcat atgtccccct gctgtgagtg gttcacccgt ccagcgggcg
     8701 tcgatgatcg aaatcgatcg taacgcgggg gtcctatcgg gttatcggcc gtcctcgtcc
     8761 tgcactgtgt gccgcggcgc cggagcacgt cgagatggtg gacgctgctg tccgggcggc
     8821 ccgtcgccgc cgggcggaat cggaccggtc tggcggcgac cgggcgacac cggacccggc
     8881 ggtaccgctc gcggaggtcg atctctgtct cccaccggct gattcacggt cgggtacgag
     8941 ttcggcagcg gtctcggagg tggggtgggc cgatatccgg gcgtagcggg tggtggacgt
     9001 cgtcccatcg acccatctcc gccaccttgg cgggcgcgat agcccggctg cggccggaaa
     9061 tccgggcgag gtggggacgg cggtacggtc ggggccggcc ggtcgcgata gcgcggctcg
     9121 aattcgcgtt gaccgggtcc gccacggaca ggctctgccg atcgatcgcg ggcggtctca
     9181 ccagcactcc tgcgctgtgt cgatggtcga gctccggact ccgccctacg cctgggggca
     9241 gcagattcgg tcagcggccg gcgccgccca cgtagtgcgg tgatcgtgcc gaatccggac
     9301 gcggccaacg caacaaacgc accgagggtg acgagccaca gtccgacacc tgcgtaaccg
     9361 attccggtac tgccggttcc gtcgagtacg gcatcacccg gagcgaacag gtactccagg
     9421 gacatgaaga ccgcgatcag cgcgagcaca gcacctgctg ccgccccgag tccgggatag
     9481 cgattgatca ccatcaggat cgccgcaccg gccagcagtg caccgaacaa cgctgtgaag
     9541 actcccggcg ctttgccccg ttcgtcgagt tcggctgcca cgtcggccga tccacccagc
     9601 gcctgggcgc gcgcctccga cgcctcgaac gacaccgaac ccatcccggt caccgacagg
     9661 ctcagctcat cgtcggaggc cgacgcccag gtgaggaaac tgcagacgac gatgagcact
     9721 cccgccgcgg cgagcaccag gcccgcgaag cgtaaacgcg aatcacctga cgacgccgcg
     9781 aacagaccac cgccagacgt cgagcgacga ccggcattct cggcggcagg cacggtgcgt
     9841 gggcgacgcc cggagggcgc ccccgcagac tgccaatctc cgggatccac gcgtgaccgg
     9901 tcgtacgtca tgtgccctca ccgatcacct cgcgcggagt ccgacccgca cccgagtcgt
     9961 caattcggac aaatggtaac ccgagtcacc cgcttcggcg tcacactccg gcgttggcgt
    10021 cctgcttttt cttcagctcg agagcgatgt cgatgagttg gtcttcctgt ccaccgacca
    10081 gtttgcgggc accggcctcg agaaggattt ctgcagccga aaccccgtat ttctcggcgt
    10141 gaccttcggc gtgcttgagg aaggagctgt agcagcccgc gtagcccatc atcatcgccg
    10201 gacgatccac cagacactca gagggcatca ccggccgcac cacgtcctgg gcggcgtcgg
    10261 cgatcttcat gaaatcgacc cccgtactga taccgagctt gtcgcagacc cccacgaacg
    10321 cctccaccgg cgtattgcct gcacctgcgc cgaatcggcg caccgatcca tcgatctgct
    10381 gtgccccggc tcgcaccgcc gcaatcgagt tcgccacggc gatatcaagg ttctcgtggc
    10441 cgtggaatcc gatctgcgca tcgtcaccga gttcgtcttt gagcgccgca acacgatccg
    10501 acacctgttc gaggacaagg gccccggccg aatccacgac gtacacgcac tggcaaccgg
    10561 cgtcggccat gatgcgggcc tgcctcgcca ggacttccgg cggctgactg tgcgacatca
    10621 tcagaaatcc gacagtctcc agaccgagtt cccgggccag gccgaaatgc tggatcgaga
    10681 cgtcggcttc ggtgcagtgc gtcgcgatcc ggcagatctg cgcgccgcca tcctgcgccg
    10741 cccggatgtc atccttgaca cccagacccg gcagcatgag gaaagcgatc ttcgcagtcg
    10801 tcgcggtctc caccgctgcc ttgatcagtt gctgctccgg cgttttcgag aaaccgtagt
    10861 tgaacgacga accacccaaa ccatcgccat gggtcacctc gatcaccggc acccccgcgc
    10921 catcgagagc gccaacgatg tcgcggacct cctgctcggt gaactgatgc cgcttgtgat
    10981 gactcccgtc ccgcaacgag gagtcggtga tccggatgtg gagcgcatcg ctgtactttc
    11041 gtgcaccggc catcaagtct gtggaattgg cgaacatgtc agacacctac ctttgctgcg
    11101 agcttctgct tggcgatctc ttcgccgacc ttggtcgccg ccgcggtcat gatgtccaga
    11161 tttccggcat acggcgggag gaaatctcct gcgccctcga cctcgacgaa gatcgacacc
    11221 cgtgccatgc cgccattgcc gacgctcggc gggtcgaact gcggatcctg caacaaccgg
    11281 tagcccggta cgtactgttg gatttccttc tcccgccggt ggatcgcctc cgcgatcgca
    11341 tcgatgtcgg cgtcctctgg aatggcacag aaaatggtgt cgcgcatgat catcggcgga
    11401 tcggctgggt tcaggatgat gatcgccttg ccgcggtcgg caccaccgat cgtctcgacc
    11461 ccgcgagagg tggtcttggt gaactcgtcg atgttcgcac gcgtacccgg ccccgccgac
    11521 ttcgacgaca ccgacgccac gatctcggcg tacgccaccg gcaccaccga cgacaccgca
    11581 tgcaccatgg ggatggtcgc ctgaccacca cacgtgatca tgttcgtgtt cggcgcatcc
    11641 aggtgctcgc gcagattcgc cggcggcacc acagccgggc ctacggccgc cggggtcaga
    11701 tcgatcgccg tgatccctgc agcctcgtac ttcggcgcgt actcgcgatg cacatacgcc
    11761 gacgtggcct cgaagatgag gtcaggtttc tcttccgagg ccagcagctc gtccgcccca
    11821 cccgacatcg tgatcaggcc gcggtccgcg gctcgcttca tgccctccga atcggcgtcg
    11881 atgccgacca tccaacgcgg ctcgatgacc tccgaccgtg ccaacttgta catcagatct
    11941 gtcccgatgt tgcccgatcc gatgatcgcg gcggtgacct tgcctgccac tggtgctcct
    12001 aacgtaaaga ctctgcggac gtgtgttttt cggactgaga aagggtcagg tgaaatccag
    12061 ggtgacgctg cccagaccga cgaaatcggc gacgaaatga tcgcccgaac gaatgtcgat
    12121 ggcgcgggtg gcggtgccgg gcaagatcac gtcgcccttg cgcaaccgca ccccgaaact
    12181 ctcgaccttg cgcgccagcc acgacaccgc ggtaagcgga tgccccagca cggcactgga
    12241 attgccttcg gcgatcaatt caccattgcg gtgcagtgtg gcatcgatgt caccggtgtc
    12301 gatgtcggag atcttcaccc gctgctcccc caggacccag ccacacgatg atgcgttgtc
    12361 ggcgatggtg tccggcagcg agatcttcca atcccggatc cgactgtcga tcaactcgat
    12421 cgagggcacc acccactcga ccgccgcgat cacgtcctcg ttggtgcatc ccgcgccggg
    12481 caggtccgca cccaagatga aaccgacctc cacctcgacc ctggggaaac agaacttcgt
    12541 ggcgtcgatc ggggtgtgct cgtggtactg catcacgtcg agcaggtggc cgtagtcggg
    12601 ctcgtccacc cccatcatct tctgcatcgc ctccgaggcg aggccgacct tgtggccggc
    12661 gaccctggca cctgcgtcga gacgccgacg gatgttgatc aactggatct cgtaggcgtc
    12721 ggtcacatcg atgtccggat aggcgaccac cggcggatcg atcgcgaccg cggacgcctc
    12781 cgccctggcc agttcgtcgg cgatctggtg acgttgctgg tcggtgatcg tcatgttctg
    12841 cctcgctctc ctaccggccc aggggaactg gaacgtgttt ctgttttgct atgcatcggg
    12901 cactcgccaa tggcttccag gctggtatag cctgcctagt gagtcagttt ataacgtgtt
    12961 ctaggttgcc gatggaagtc gggcggcttg acgggcagtt tcggcgtgaa ggggcgagaa
    13021 agatgaccag ttcggaccag acagggtcag gaccgacctc tgtggatgag accttcgatg
    13081 tgatcgtggt cggtgccgga ggcgcaggga tgagtacggc gatcaccgcc gccgcacacg
    13141 gcctcgacac cgtcatcgtc gagaagtcgg cgtactgggg cggctccacc tcccgctctg
    13201 gcggcggcgt atggattccc aacaacaagg tgctgcagcg cgacggggtc aaggacgacc
    13261 cagaggccgc gcgcacctat gtccgatcga tcgtcggcga cggcgtggcg cccgaacgca
    13321 tcgatgcgta catcgaccgc ggtcccgaag ctctcgcgtt tctctccgag aactcacctc
    13381 tcgaactcga gtgggtgaag aactactccg actactaccc ggaggccccc ggcggtcgcg
    13441 tgggcggccg ctcgtgtgag cccaagccgt tcgattcccg caaactcggt gacgacatca
    13501 agaccttgca tcccccgtac agcaaggcgc ccctgaacgt cgtggtgatg cagtccgact
    13561 accgctggct cagcaccggg ctccggcact ggaaagggcc gttgcgggca gcgaaggtcg
    13621 gctcgcgctt catctgggcg aagctgaccc gcaagaagct catcgccatg ggcgccgcac
    13681 tgatgtccga actcctcttg ggcgtacggc aggcgggtgt cccgctgcga ttgaacaccc
    13741 cactggtcga cctcgtcacc gaaggtggac gggttgtcgg gatcgtcgtc gaatccgacg
    13801 gcaagaccaa gacgttgcgc gcccgccaag gtgtggtcct ggcctgcggc ggattcgagc
    13861 acaacgacga gatgcgccac aagtatcagc gggagcccat cggttcccag tggaccacgg
    13921 gcgccgagtc gaacaccggg gacggcatca acgccggcct gaagatcggt gcgggcgtga
    13981 gctacatgga ggacgcctgg tggggtccga cgattccact gccacgtggt ccgtggttcg
    14041 cgttgtccga gcgggccttg cccggcagtt tcatgatcaa tgaccgcggc cagagattca
    14101 tgaacgaatc cctcccctac gtcgaagccg tccatcagat gtacggcggg gagttcggtc
    14161 agggcgaggg cccgggcgag aacctgccct gctggctcgt cttcgaccag acctaccgca
    14221 accggtacat gttcgcctcg gtatccggcc gccaaccgtt gccgggtaag tggttcaagt
    14281 cgggcgtgat cacgaagtcc gagaccctgt ccggcctcgc ggagaagatc ggcgtacctg
    14341 ccgaagggct gacgcagacc gcggaacgct tcaacgcctt cgcggccgca ggcaaggacg
    14401 aagatttcgg ccgcggcgtc agccggtacg accactacta cggcgacatc accaacaagc
    14461 ccaacccgag tctgggtccc ctgaagaagg gaccgttcta tgcggtcaag atggtgccgg
    14521 gcgatctggg caccaagggc ggcatcaaca ccgacgccgc cgggcgcgcg ctgcgggcgg
    14581 acggctccgt gatcgagggg ctgtatgcgg cgggcaacac cagctcgccc gtgatgggac
    14641 atacgtacgc cggtcccgga gccaccatcg gtcccgcgat ggtgttcgga taccttgccg
    14701 cgctggacat cgcgaccaat gcgcagagca gccgggccac cgaagagaag gcgggctgat
    14761 gccgatagat cccgacgtcg ccctcggcgc cgtggtggcc aaggagacgt tcagctggag
    14821 tgcctccgac gtcgcgctct acaaccttgc cgtgggcgcc ggctcggacc cgctgaacgc
    14881 cactgctctc gagtatctcg atgaccgacg gccgaaggtc ctttcgagct tcgccacggt
    14941 cgcggcgcac tttcacgaga ccgagcctcc gaaggtatcc aagcccggaa tcgagataga
    15001 cctgggctcg gtggtgcacg gggcgcagga ggtgcaggta cacaaaccga ttccagccat
    15061 gggcaccgcc accaccacga ccaccgttgt cgagttgcag gacaagggtt ccgccgcggt
    15121 catcatcgaa gagtccgtca cggtcgacga tgggggcgag ccactgtgga ccgcccgatc
    15181 atccatcttc tgcaaaggcg ctggaggttt cggcggcgaa cgtggcacgt cggacaaggt
    15241 caactacccg gaccgggaac ccgaccacgt catcgaagag aagacccttc cgcagcaggc
    15301 cctgctgtac cgcttgtgcg gagaccgcaa tccgttgcac tccgaccccg catttgcgga
    15361 gaaggcagga ttcccgcggc cgatcctgca cgggctgggc acctacggaa tcgtgctgcg
    15421 cacagtggtt gatgaactgc tcggcggcga cgtcgatcgg gtcgcgagct tcggcgcgaa
    15481 gttcgccgga gtcgtctttc ccggagaaac cctacggatc aaggtgtggg acgacgactc
    15541 ccgactgttg atcaccgcgt cagtggtgga gcgggacgac tcccccgccc tcggcaacgt
    15601 ggtgctcacc aagcgctagc gatgagcgag gcctcaggcg gcgctcatga atatggcgac
    15661 gagcccgacg atgacagcca ccagcgaggc aagcatcgtg agaacccgcc ataggcggag
    15721 tttgactgca gagacgtcgt tgacctgaga tgtggccatc ggattccctc tcgtccgagt
    15781 gcggctgatc cggatggtca gccttaccag caacgcggcg atttcagtta ccagtgtgac
    15841 caatgtgaca caagagacac aagttatgtc gaagccacac cgtacgacgt gataacgatt
    15901 acacaacgtg aacttccgat acgtgccggg tgttctgact aggttggatc aatgaaatca
    15961 acggtggggg cgtcaccaga cgagagaatt ggtctccgga ccgtctggct cattttcgtg
    16021 gcctgtgtcg cggtcagcat ggtcatcgcg gccatggcat cgctgaacac cgcgatacct
    16081 gatatcgcgc ctgcagtgca ggccaattcg aatcaggtca catggctgat cgacgggtac
    16141 acattgacgc ttgccgcatt gctgctcccg gcgggcgcga tcggagaccg cttcggccgg
    16201 cgagaggttc tcatcgctgg cctgatcgtt ttcgcgatcg gttcacttct gccgatctgg
    16261 gtttccgatc ccacccaatt catagcggcc cgttgcctca ccggggtcgg cgcggcattc
    16321 gtcatgccgg cgacactatc tttgatcacg tcgggggttc cggcgtcgaa acgtcccctg
    16381 gccgtcagca tctgggccgg tgtcgccggc gccggcggca tcgcgggctt cttcgtcacc
    16441 ggcgtgctgc tggagttctt ttcgtggcac tccattttcc tgacattcgc gatcgcagcg
    16501 gccgtcaccg cggtcctttc ctgcacgatc ccgacctcgc gcgactcgac gtcacccaag
    16561 ttcgatgtct ggggctcggt gacctccgca ttggcggttg ccctggtggt tttcgcgttc
    16621 atcgagtcac cgcatcgcgg ctggttcgac ccgctcacgg tgaccgcgtt cgtcgtgggc
    16681 atcggactgg ccgcggtctt ctggtattcg caatcacgtc gtgccgaacc actgctcgac
    16741 gtcaaactgt tcggcaacag tgctttcgct gcggggtctt tcagcgtgat gatccagttc
    16801 atggttgcat tcggcctgtt cctggtcttg ctgcaatacc tacagttggt attcggatat
    16861 tcaccgctga aatccgcgat tgcactgttc ccgatggtca tcgtcgtcat ggtgtgttcg
    16921 ctcatcggca actggatcgc ggtgaaggtc aatctccgga tcattctctc ggcggggatg
    16981 ttggtgatgg gcgtcggagt gatactcctc ggtgtcatcg cccactcaga atattggact
    17041 gtcgcggtct gcctcgtggt gttcgccctc ggtctcggaa tcgcgaccgc cccatccacc
    17101 actgcgatca tggtgaacac tcccgccgac aatcagggtg tcggatccgc catcaacgac
    17161 acgtcccgcg aactcgggtc agccatcggg atcgccatcg cgggaagcct gctggcctcc
    17221 ggatacaccc gcgacgtcaa cgccaccgcg gatgctgccc aagcccagtt gcgccagacc
    17281 gcctctcagc tcgaatccgc agggcaggtc ggtcgggcgc aggaggtcgc agccgcggca
    17341 gacggcatca aggaacacat caccaacacg ctggccgagg cgcttcaggt ggccgaacgt
    17401 ctggcgcctg agcaaccgga gttggccacc cgtatcgcag aaggcgccaa agacgccttc
    17461 atcgggccca tgaacgcggc gtccatcacg ctcggtgcac tcagtatcgc ggccggcgtc
    17521 atactcgcaa tcttcacgcc gaaccgcatg gactccgacg tggagccgga gaagctgagc
    17581 gaccggtgag acggggctag accgtggtac ccgcaaggtc gagtgcggcc tgcttggccc
    17641 acttgtaatc ggccttcccg gcaggtgtcc gcttgatctc gtcgacgatc acgagcagtc
    17701 gaggaatctt gtagcccgcc agcatcgttc ggcaatggga ttggatctcg tccagtgagg
    17761 gttcggcgat gccggggcga atcgccacga ccgccgacac cttctgaccc atccgttcgt
    17821 cgggcgatgg caccacgagc gcatcggcca ctgcggggtg cgcgtgtagg cacgcctcca
    17881 cctcttcggc gtacaccttc tcgccaccgg tgttgatgca ctgcgatccg cggccgagga
    17941 agacgatggt cccatcggct tcgaccagac ccatgtcgcc gagtactgcg accctggttc
    18001 cgtccggcag ctgagggaag gtgcgcgcgg acttctcctc gtcgcggtag tagcccagcg
    18061 gtacccggcc tatccgagcg atcatcccga cgtcacccga gcccgcgggg atcacgttca
    18121 gcttctcgtc gagcacggtc atctttgctg tcggcggcat cgcgagggtg ccgtcgtcac
    18181 gcacctcgaa cgcaccgtcg ttgccggtct ccgacgcacc gaagttgtcg cgcaggacca
    18241 ggtccggctt caccgcgagc attcgttcgc gcacccccac cgaccagacc gcgccgcccg
    18301 aggtgatcga gaagagggtc gagagatcga cctcgtcctt cagcttctcc atcgcgtcgg
    18361 cgagcggcga ccccatgccg tcaccgacga tgagcaccac attgaccttg tcggtctcga
    18421 tcgagcgcac caccttctcc ggatcgaacg cccgcatcag cacgagtcgc gcgccgaggg
    18481 tgaggaacgt gaagagggag tagagcgcag caccgtgcat caggggcgca gcgatgagga
    18541 aggacagacc cgggaactcc tttgccgcgg ccccgacctc ggcgagatct ttgcgcggat
    18601 tctcgtcgta cggattgccc ccggaaagcg gcttgtggaa gaagtcgtcg tgccgccaca
    18661 tcacgccttt gggatagccg gtggtgccac cggtgtacag cacccagagc tcgtctccgg
    18721 tccgcggctc gaagttgcgc gcctcggact ggtcggacgc atcgaacggc cgcacccgca
    18781 cacccgcgtc cgccgcggcc gcggacagcc cttcggtgat gtccccgatg acgaaaatgg
    18841 tgcgcaaggt ggggatctca ccgacgatct gcgcgaggtt gtcctggtgc tcggcctcct
    18901 cgacgacgat ggcgaccgag tccgagttct cgaagatgta cagcagctct gccggggtgt
    18961 accgatagtt gatgttgatc ggcacggcac ggatcttgat gacgcccagg atggtggtga
    19021 cgtgctcgac cgagttcttc aggaagagcg cgacatgctc gcccgcggcc acctcggccg
    19081 cagtcaacat gtgcgcgacc tgattcgctt cgacctcgag ctgccgatag ctgtggtcga
    19141 cgccttcgta ggtcagggcg atggtgtcgg gaacagaatc cgcgacagtt tcgaatacgt
    19201 cggcaagatt gaacgccatg tgtgcagctc ctaagccgtg agaaccaaac cgcttgtggg
    19261 gactccggtt ccggcggtga ccacgacctt acgtgccccc ggtacctgat tgaccgattt
    19321 tccgcgaagt tgtcggaccg cctcggcgat gccgttcatg ccatggatgt acgcctcacc
    19381 gagttggcct ccatgggtgt tgagcggcag tcgtccgccc acctcgagag ctcccggttc
    19441 ccggacgaag tctttcgctt caccgcggcc gcagaatccg agttcctcga gttgcatcag
    19501 cgtgtacggc gtgaagtggt cgtacagtat cgccaggtcg acatcttccg gaccgagatc
    19561 cgactgctcc cacagttgcc tgccgacgag tcccatctcg ggcaaccccg caagatcgtc
    19621 ccggtagtag ctggtcatga tgtattgatc gtcaccgctg ccggacgcgg caccggcgat
    19681 gatcgcgggg gtgtgcggaa ggtctttggc ccgctcggcc gacacgatca cgaatgcaac
    19741 gccgccatcg gactcctggc agcagtcgag aagatgcagc ggctctgcga tgtaccgaga
    19801 gttctgatga tcttcgaggg tgatcggttt gccgtagaag aaggcctccg ggttcacggc
    19861 cgcatgcttg cggtcgacga ccgagatgcg tccgaagtct tcgctggtgg cgccgtattc
    19921 gtgcatgtac cgctgggcga ccatggccac gaaggcggcg ggcgtgctca acccgtgcgg
    19981 atagctgaac gcgttgtcgg tcccggacga gttgtcctgg gccaccagag aggtgttgac
    20041 ctgaccgaac cgcatccccg aacgctcgtt gaacgcgcga taggcgacca cgacgtcggc
    20101 cacccctgtg gccactgcca tggcagcctg ctgcacggtg gaacacgctg cgccgccccc
    20161 gtagtggata cgcgagaagt aggtcagctc accgataccc gacgccctgg cgaccgcgat
    20221 ctcggtgttg gtgtccatcg tgaacgacac cagcccgtcg acgtcggcag gtgtgaggcc
    20281 ggcatcggcg atggcggcgg tgaccgcctc ggccgcgagc cggagttcgc tgcgccccga
    20341 gttcttcgag aagtcggtgg cgccgatccc ggcgatggcc gccttgccgg acaatccgct
    20401 cactgtgcca ctcccgcttc actcgtggaa ccggagaccg cggcggtggt gtgatccatc
    20461 accaacgtca ccaccgacgt gacgtgattt ccgagaccgt ccttgccgat aacgtcaacg
    20521 gtcacgaggt caccctcgac cgacgacacg gtgcccgaca gggtcaacgt gtcgtaggcg
    20581 taccagggca ccccgagtcg gagttttatc gaccggatct gggctcgctg cccagcccag
    20641 tcggtgatgt accgctgcac cagaccggta tcggtcagga tgttgacgaa gatgtccttc
    20701 gaccccttgc tgtgggcaag gtcgcggtcg tggtggacat cctggaagtc cctggtggcc
    20761 agcgcagtag acaccacgaa agtcggtgtc gcggtgacgg tgagctgcgg aagctcggtc
    20821 ccgaccgctg cctgtggcgg tgttgcgggg acggtcatga aagctctcct gccggttgcc
    20881 acgcgtacag cgtccacgct tcggtctgtg cagcactgtc ggcggggaag tcgaggaact
    20941 cgacctgaac gggtagcccg acagtcacct gcgccggctc gatcccgcgg agttcgccga
    21001 gcagccgcac gccttcgtcg agttccacga gcgcgacgac gaacggtagt gtccgtcccg
    21061 gaaccttggg agcatggtgc accacatagc tgtagacggt gccgcgaccc gacgacacca
    21121 catagtcggt gtcctcgcct ctcggtttcc acagcgccgg gatcggcgga tgacgcaggg
    21181 ttccgtcgtc gactttctgg atccgcagct cgtgttcacg cacgccgttc cagaagaaca
    21241 gggtgtccag cgatggggtc ggacgcatca tcttggccgg gtcgacatca gccgttgctg
    21301 cgccgagcga cgagatgacc tcgccaccag cgggttcggt gatcgccgct ttctccgcag
    21361 gccggaactt gaggatgcga aagtccatct cggcgacgac ttcgtcaccg accttccaga
    21421 tgttcttggt cgtgaagaac cagccctcgc cgagtgcggt ctgtttcggt ccgacgacat
    21481 cggtgagtgc ggactcgatg gtcacgtgct caccgggcac ggtgtaccgg tggtacgtcg
    21541 agtcgcagtt ggtcgcgacc accgacgagt agccggccgc gtcgagtatc tcggtcacct
    21601 ggcccagcgg gtcatcctcg gcgcgaactc cgttgagacc acgcatggtc cacacctgcg
    21661 ccatcgccgg tggggcgacg acgtcgtcat acccggcggc gcgagcggcg cccgggtcga
    21721 cgtagatggg attggtgtcg ccgatcgcct cgacccagtt gttgatcatc ggggtgttga
    21781 ccgggtcacg gcccgccagc ggcgcactcg tacccgcatc gcggacctca tcggtggccg
    21841 ccaggatcgc ggtcgtggtg tcgctcatcg tttaccccgg ggcagaccga gacccgcagt
    21901 ggcgatcatc tcgcgcatga cctcgttcac cccgccgccg aacgtgatga cgacgttgcg
    21961 tttggcctgg acgtcgaacc agtcggccaa ctccgccgtt gccgggtccg agaagtcccc
    22021 atgacggccc aggatttcgt cgatcaaccg gtgaacgtgc tgaagtcgtt cggtggcaaa
    22081 tactttggtc gctgccgcat cggccatcga gatcgagtcc ccaccggagg cgacctgcca
    22141 gttcagcagt tcgttgatcc ggtagtaggc gtgcagttcg gccagtgccc ggcgcacatc
    22201 cgtgtgcttg cccgggaccg taccgtccgg acccggccga ttcgcccagt ccgtgatgcg
    22261 cgcgagcagg ccgtcgagcc ggccggcggg ccccaacatc acgcgttcgt ggttgagctg
    22321 cgtggtgatc agacgccagc cgccgttcac ctcgccgacg accatgcccg ccggcacgcg
    22381 gacgtccgag taatacgtcg cgttgacatg gtgcgcgcgg tctgcggtga tgatcggggt
    22441 ccagctgtac ccggggtctt tcgtgtcgac gatgagcatc gagatgccct tgtgcttggc
    22501 cacatccttg tcggtgcgga ccgccagcca tacgtagtcg gcgtcgtgac cgccggtggt
    22561 gaagatcttc tggccgttga cgatgtactc gtcgccctgg agtaccgcac tggtcttcag
    22621 cgacgcgagg tcggtgcccg cgtcgggttc ggtgtagccg atcgcgaagt ggacctcacc
    22681 ggccaggatg tcaggcagga accgctgctt ctgctcgtcg gtgccgtagg cctgcagcgt
    22741 cggccccacc gtctgcaagg tgaccgcagg aagcgggatg tcggcacggg cagcctcgtt
    22801 gacgaagatc tgctgctcga tctggccgaa acctcggccg ccgtactcct ttggccaccc
    22861 gaccccgagc cagccatcgc tgcccatctg acggatgacc ttgcggtagg tcggaccgtg
    22921 ccgctcggtc agcatcgtgg tcgcgtcttc gggcgatacc aggttcgaaa agtactcgcg
    22981 cagctccatt ttcagggatc gctgctcgtc ggtcagatcg atgaacattt ctacactcct
    23041 gcctcaacct gttgcgccaa ggcgtccagc cgaccggtgg gccccccgac cagcctggcc
    23101 aggtccttgg cgatggaaaa gtaacggtgc agcgggtagg tgagatccac tccgacgcct
    23161 ccatggaggt ggatcatggt ccgcatggtg gccgggatct cctgcgccag ccagtatccg
    23221 gacaacgcca gatctgttcc ggcatcgagt ccttcggtga gcctccagcc tgccgaggtg
    23281 gtggccaacg tcatcgaccg ggcgacgacg tagatgtcgg cgagctgctg ctgaacggct
    23341 tggaacgtgc cgatcggctt gtcgaactgg acgcgttcgg agacatgggt ggccgtcagc
    23401 ttcatggccc ctgccacgag cccgtcagcg taggcggcga tcccaaggct gtgatgctgc
    23461 tgcagccaac ccggatcacc gtcgatgacg gagtccgctg cgacgtcggt gagcacaacc
    23521 gtgtactcgc cccatcccga tgacgaggtg gtcctggtca tccggacgcc aggggcgtcg
    23581 gcggggacca cggcgacccc ggcatcggtg gagacgagga tcgcggacgc gccctcggcg
    23641 tgcagaacgc cggtcttggt cccggagagt ttgccgttcg agatcgttgt atgcggcgta
    23701 tcggtcaggg ccgcccccgg ctcgctgatc gccgtcgcca gccagccacc ggcctgaacc
    23761 cgggctccca gggtcgcggc cacgtcaggc gcgcgatgtg cgagcggcgc caatcctgcg
    23821 atcagcgtcc ctatcgcggg cgtgactgcg gcggcacgac cgagtgccgt ggggatcgga
    23881 accagcccgc ccaccgcgac gtcgtcgccg cccgaggcct ctggcagcgg cagggccaac
    23941 aaccctgatt cggccagcgc tgcccacagc gaggtctcga agccaccgac gtcggtgagg
    24001 cccgcatccc agatcgactc gtgccgttgt aggacggagt cgatgacatc actcacagtt
    24061 tcagctgtgg agtcgcgcgt gaagtccact atttacacct cttcagcgaa ttagaacctg
    24121 ttctagttgt atcagagatc gggcggtctc agcgaggcaa tcccagtagc cgttcggcgg
    24181 cggcggtggc gaggatctgg gtggttccac cggcgatcga caggcacctg ttcaagagga
    24241 aatcctgtga ggccgtcgac tgcgccagcc cggcgacgcc gtggagttgc tgtgcgaact
    24301 caggcaccgc ctgtcgatgc cgcacgccga taagcttgcg cacactcgac gccgcaccgg
    24361 ggtcggtgcc gttgatcgat ccgagtaccg aacgcagatc gagcacctgc cccagttgcg
    24421 cctgagcgat caactcaccg agcttctcgc attgcgtccc ggtgagctcc ccgcgctccg
    24481 tccccgtttc accaccgtcg atctgcgcca gcagcgcttc catctccttg cccaacgccg
    24541 aaccacccat ggcgacccgc tcgttggcca gggtcgtccg agccaatcgc cagccattgt
    24601 tgatctcccc caccacgcag tcgtccggga cgaacacatc gtcgaggaac acctcgttga
    24661 acatcgcccg gccggtgatc tcccgcaacg gccgcgtctc gatccccgac gacgtcatgt
    24721 cgacgaggaa gtacgtgatg cccttgtgtt tgggcgcgtc cgggtcggtc cgcgccaggc
    24781 agatcgccca atcggcatcg tgcgcgtgcg aggtccacac cttctgaccc tgcaggctcc
    24841 agccaccttc gacccgtgtc gccttggttc ggagcgctgc cagatccgag cccgccccgg
    24901 gctcggagaa cagctgacac cacatgacct cgccgtcgag cgtcggcttc acgaatcgtt
    24961 cgcgctgccg gtcggtgccg tgctcgatga tcgtcggtat ggcccagccc gcgatgacca
    25021 ggtcaggtct gcgcacccct gcacgctcga gttcctcgtc gatcagcacc tgccggacgg
    25081 cgtcggcacc gagaccgaac ggcgcaggcc agtgcggcgt caggtaaccc gtctcggcga
    25141 gcgcccggcg ttgatcaccc gcggcagcaa tcgcctcggc gtccgcgcgc acctcgcggc
    25201 gctgcccctc ggcatccgag agatcgacgc gcagcttccg tcgcacaccc cgccgattca
    25261 gctcggcgat cgcggcgtgc cagtgcccgg gcgagcccag ttgggcctgc caggccaggg
    25321 cccgtcggag gtacagatgg gcgtcgtgct cgaaggtgaa cccgatgccg ccgaggatct
    25381 ggatgcagtc cttcgcattc gcgaccacca tctccgacac ggcggccgcg gcgaccgcag
    25441 cactgatctc cacctgttcg gcggcgccgg cgcgctccgg gccgtcggcg tcggtcagct
    25501 catcgacggc ggacgcgaga tcccaggccg cggcactgac ctgctcgctg cggcacagca
    25561 tctctgcgca gatgtgctta acagcctgga agctgccgat cggcgccccg aactgctccc
    25621 ggaccttggc gtattcgacg gcggtgtcga gggtccaacg cgccactccg gacgcctgcg
    25681 cagcgatgac cgcgatgatc gtggctcgga cgaaggcgtc ggagacgtgc agtacgtcgt
    25741 gtgccgggat gaccacgtcg tccaagcgga cccgcgacag cgccatcgag aagtcgaggg
    25801 cctccaccgg ttccgacacg atgcccgagg tacccggctc gagcagcacc caccggtggc
    25861 tgcccgcgat gtcgatcggt gccagcaatg cgacatcggg cgcgtatccc gcgaccagtc
    25921 ccaggtcacc ggacgccgag agcacgccct tcggatgatc gggatccgcc tcgccgcgtc
    25981 cacgctcggg gtccacagca cggggtgcaa ccgctccggc cagcaccgag gtcgccactg
    26041 ccgcgccgac gtcccccgcg atcagctgcg cgagtaacgc gttctcgttc ggagagcccg
    26101 acagcgaggt cagcagtgca ctcagggccg ttcccgccac cggcccgggc accaggtcgt
    26161 aaccggtctg ctcgagcatc accgccaggt ccgtgaacag tgcgtccatc ccacccttgc
    26221 cctccggcac agccgccgcg aagatcccga gctcggccaa ttcccggaac agcgcaggcc
    26281 agggttcggc agtcaggtcg gaccccggtt cgccggcccg caccgtcgtg atgaccgaca
    26341 cctttttgga ccattgacca attgcgtcgg cgacagcggt atgttctggg gtggtagcaa
    26401 tggtcacgga agtctttcct tgcctgctcg gggttgtcgg tgcgtagtag aacctgttct
    26461 aatattgcac gtctgccggg gcagaatgaa ggggaccgtg tcgcagagtc cagaaagtaa
    26521 cgttttcgct gccagcgatt aacgtggaga cgacaacgcc acctgctcga tgaagtatcg
    26581 acaaccgaca gatgagaaag tggggacgcc ccgatggcta gcccgatacc ggccggcaac
    26641 tcggccagcg acgtggccgt cgggtccgac gtggacctcg ggtccagcgc ccagcgcgaa
    26701 cgccgccgcc gcatcctcga cgccaccctg caactcgcct ccaagggcgg ctatgacgca
    26761 gtgcagatgc gtgccgttgc cgagcgtgcc gatgtcgcgg tgggcaccct ctaccggtac
    26821 ttcccgtcca aggtccatct cctcgtcacc gcactcgccc gcgagttcga ggcggtcgag
    26881 agtcgggcgg acaagacaag gctccgcggg aacacggccc tcgagcggct ccgccacgtc
    26941 ctcgacatga tcactcttgc gatgcaacgt gatccgctgc tgaccgaagc catgacccgg
    27001 gccttcatgt tcgccgatgc gtccgcgtcg gccgaggtcg acaaggtcgc actgatcatc
    27061 gaccgcctct tggccaacgc gatggtggag ggcgagccga ccgaactcga cctgaagatc
    27121 gcgcgcgtgg tctccgacgt ctggatgtcc aacctcgtgc agtggctgac ccgccgcgcc
    27181 tcggcgaccg atgtgaccaa ccgcctcgag ctcacgatca ccctgctgct cgccggccgg
    27241 gaccaggacc ccgaagtcaa agactgaccc gctctacaaa agcaccccgt tcagtcaaag
    27301 gcacctgttg caacaggtgg gtttgactga acggggtgct tttgtttggc ctcacgacag
    27361 aaggggcgca atcgctttcg cggttgcgcc ccttctgggt tcagtgctta cttctcggag
    27421 tcaccggtct tggccagttc caccggggtg tcgggaagcg cgatcggctt cttcgaaccc
    27481 ttgaaggtga acttggcttc gtcgtcgtcg gaggcgacgt caccgtccca gttctcgaca
    27541 tcgacgagga tgatctcgcc ggcaccgatc tcgttgaaca ggatcttctc ggacagctga
    27601 tcctcgatct cgcgctggat ggtgcgacgc agtggccgag cacccagtac cggatcgaag
    27661 ccgcgcttgg cgagcagact cttggccttg tccgtcagct cgagggccat gtccttgttc
    27721 cgcagctgcg tctcgacgcg ggcgatcatg agatcgacca tcttgatgat ctcgtccttc
    27781 gtgagctggt ggaacacgat gacgtcgtcg atacggttga ggaactcggg ccggaagtgc
    27841 ttcttgagct cgtcgttgac cttctgcttc atccgctcgt agttcgagcc ttccgcattc
    27901 gactgggaga agcccagacc cacggccttg gagatgtcgc cggtaccgag gttggaggtg
    27961 aagatcagca cggtgttctt gaagtcgacc gtacgaccct gaccgtcggt gaggcggccg
    28021 tcttcgagga cctgcaggag cgtgttgtag atctcctggt gggccttctc gatctcgtcg
    28081 aacaggacga cggagaacgg cttgcgtcgc accttctcgg tgagctggcc gccctcttcg
    28141 tacccgacgt acccgggagg ggcaccgaag agccgcgatg cggtgaagcg gtcgtggaac
    28201 tcgcccatgt cgatctggat gagcgcgtcg tcctcgccga acaggaagtt cgccaacgcc
    28261 ttggacagct cggtcttacc gacgccggac gggccggcga agatgaacga gccggacggg
    28321 cgcttggggt ctttcagacc ggcgcgggta cgacggatcg ccttcgacac ggccttgacc
    28381 gcctcggtct ggccgatgat ccgcttgtgc agctcctcct ccatacggag cagacgggtg
    28441 gtctcctcct cggtgagctt gaagacgggg atgccggtcc agttacccag aacctcggcg
    28501 atctcgttgt catcgacctc ggcgacgatg tccatgtcgc cactgcgcca ctgcttttcg
    28561 cgctcggcac gctcggtgac gagctgcttc tccttgtcgc gcaggttcgc ggccttctcg
    28621 aagtcctgcg cgtcgatcgc cgattccttc tccttgcggg cgtcggcgat cttgtcgtcg
    28681 aactcgcgca ggtctggtgg tgcggtcatc cggcggatac gcatccgggc gccggcctca
    28741 tcgatcaggt cgatggcctt gtccggcagg aaccggtcgt tgatgtaccg gtcggccagg
    28801 gtggcggccg cggtcagtgc gccatcggtg atcgagacgc ggtgatgcga ctcgtagcga
    28861 tcgcgtagtc ccttgaggat ctggatcgtg tgctcgacgc tgggctcgcc gacctgaacc
    28921 ggctggaagc ggcgctcgag ggcggcgtcc ttctcgatgt acttgcggta ctcgtcgagg
    28981 gtggtcgcac cgatggtctg caactcaccg cgggcgagct tcggcttgag gatgctggcg
    29041 gcgtcgatcg caccttcggc agcacctgcg ccgacgagtg tgtgcagctc gtcgatgaac
    29101 aggatgatgt cgccgcgggt gttgatctcc ttgagcacct tcttgaggcg ttcctcgaag
    29161 tcaccgcggt agcggctgcc tgcgaccaac gaaccgaggt cgagggtgta gagctgctt
//
