LOCUS       NZ_CP029541            24637 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. NEAU-S7GS2 chromosome, complete genome.
ACCESSION   NZ_CP029541
VERSION     NZ_CP029541.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. NEAU-S7GS2
  ORGANISM  Streptomyces sp. NEAU-S7GS2
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9641634)
  AUTHORS   Zhang,J.
  TITLE     Streptomyces sp. NEAU-S7GS2 isolated from saline-alkaline soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9641634)
  AUTHORS   Zhang,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2018) School of Life Science, Northeast
            Agricultural University, Mucai Street, Harbin 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: AMRT Link v. v5.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003173275.1-RS_2024_05_07
            Annotation Date                   :: 05/07/2024 05:28:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,458
            CDSs (total)                      :: 8,365
            Genes (coding)                    :: 8,052
            CDSs (with protein)               :: 8,052
            Genes (RNA)                       :: 93
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 313
            CDSs (without protein)            :: 313
            Pseudo Genes (ambiguous residues) :: 0 of 313
            Pseudo Genes (frameshifted)       :: 144 of 313
            Pseudo Genes (incomplete)         :: 230 of 313
            Pseudo Genes (internal stop)      :: 21 of 313
            Pseudo Genes (multiple problems)  :: 74 of 313
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:52:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8787518
            Orig. end                         :: 8812155
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029541.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24637
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="31"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24637
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24637
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14637](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14637)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    164..178
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.22"
                     /tool="antismash"
     gene            complement(294..965)
                     /locus_tag="DKG71_RS38205"
                     /old_locus_tag="DKG71_38205"
     CDS             complement(294..965)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005317456.1"
                     /locus_tag="DKG71_RS38205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38205"
                     /product="DUF4142 domain-containing protein"
                     /protein_id="WP_229837870.1"
                     /transl_table=11
                     /translation="MKSHARKSQPTSSRGRLIAATVALIAAIATVSVWLSQRNSSADEP
                     ASAHAPAARAPLAGPGGGNTGAVGALDKTFLTKVRQAGLWEMPAGRLAQTHASSEAIKR
                     AGMHLLEGHSKLDQLAREDSEALNVPIPDEATAEQQGWVDQLEKARGKEFDQIFVDLLR
                     ASHGKIFITIGEVRATTKNSLIRRLATQTNNTVQDHMEVLEDTGLVTDATLDDVASTVP
                     K"
     misc_feature    1044..1056
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            1345..1812
                     /locus_tag="DKG71_RS38210"
                     /old_locus_tag="DKG71_38210"
     CDS             1345..1812
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088650.1"
                     /locus_tag="DKG71_RS38210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38210"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_093639455.1"
                     /transl_table=11
                     /translation="MDDVDAVTRAVLTASRLLVAVSARSLGEAEERVTLPQLRMLVVLS
                     TRGATKLVALAELLQVAPSTAMRMVDRLITAGLAHRQANPGNRRETLLQLTDEGRRTVE
                     EVTARRRAEISAIVERLTPEQRASLIEALTAFNEAGGEPPVDSREETHPLG"
     gene            complement(1852..2292)
                     /locus_tag="DKG71_RS38215"
                     /old_locus_tag="DKG71_38215"
     CDS             complement(1852..2292)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088651.1"
                     /locus_tag="DKG71_RS38215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38215"
                     /product="hypothetical protein"
                     /protein_id="WP_109894823.1"
                     /transl_table=11
                     /translation="MGTASHTTAETAHLNRPHPHRAFGRVKALVAAYGALSAAVLITVV
                     VLASTGHTVTAFMWGRSAGVLASAAVAYWLTVLASRGARGAYLRVRIISVVVPIAIVAI
                     DMIPGALPPWFVLMQVGCALVLGATAFLVNGSGLRAAFPVSR"
     gene            2554..3831
                     /locus_tag="DKG71_RS38220"
                     /old_locus_tag="DKG71_38220"
     CDS             2554..3831
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088652.1"
                     /locus_tag="DKG71_RS38220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38220"
                     /product="histidine kinase"
                     /protein_id="WP_109894825.1"
                     /transl_table=11
                     /translation="MRQVVSWMAGACVGFARACVVVAVSMLVPAVWAAAVAVAIRWGAG
                     NPWSWVPVLVLGSVGTLALSRPVCRMFRFLVATWTATDIPAGYRRAEPVVRMSTGYWWN
                     GFSYERTRRDALLDQRWRIRWSDSATWRDLRFTGIAPITAGAIASLPPAGVAVAFLGFG
                     QPELSARLVGVLGLIAAVAGAPYAWRSAEPVAVRFLRASPAMVLADRVAELTAQRADTT
                     VAQAAEIRRIERDLHDGAQARLVGLGLSLATAEKLMETDPDQAKALMREARAGAATSLT
                     ELRELVMGINPPVLNERGLIDAVRALALDSPLEAVVSAEVPLRLDPPIESALYFGIAEL
                     VTNATKHARATRARISLSRDDTGTGTGTGIVVDVEDDGRGGADVRAGGGLEGLRRRLAV
                     FDGTLEITSPAGGPTRVRMMVPCASL"
     gene            3816..4463
                     /locus_tag="DKG71_RS38225"
                     /old_locus_tag="DKG71_38225"
     CDS             3816..4463
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104221.1"
                     /locus_tag="DKG71_RS38225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38225"
                     /product="response regulator transcription factor"
                     /protein_id="WP_109894827.1"
                     /transl_table=11
                     /translation="MRIVVAEDLYLLREGMVRLIEAYGHQVVATAATGPETLDALLTWR
                     PDVAVVDIRMPPTQSDEGLRVALAARSELPGLPILILSQHVVQLYARELLADGAGGIGY
                     FLKENVFDADQFIDALERVAGGGTAMDPAVIAALLSSGSSHRRLEGLTEREHSVLSLMA
                     EGLSNQAIGRRLYLSDSAISKYTTSLFGKLGITDDGTANRRVLAVLTYLNEP"
     gene            complement(4536..4769)
                     /locus_tag="DKG71_RS38230"
                     /old_locus_tag="DKG71_38230"
     CDS             complement(4536..4769)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088654.1"
                     /locus_tag="DKG71_RS38230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38230"
                     /product="hypothetical protein"
                     /protein_id="WP_109894829.1"
                     /transl_table=11
                     /translation="MDRHELRTALTAAGVADGYYRIEGVHEPVPTPPDFLYLRRTADGA
                     WETGAYERGTCRPIARHLDEEAACAHLWRLLT"
     gene            complement(4777..5409)
                     /locus_tag="DKG71_RS38235"
                     /old_locus_tag="DKG71_38235"
     CDS             complement(4777..5409)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088655.1"
                     /locus_tag="DKG71_RS38235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38235"
                     /product="TNT domain-containing protein"
                     /protein_id="WP_109896741.1"
                     /transl_table=11
                     /translation="MATAPAAAAAPHQQERQRPAAAPRPAPCTGEFQGEARLGPKRLPK
                     KWHAPVGPLLNGWKRTGALSPSAFLKKYWQGPADSGSWKYPPNDGFAEVNGEIDKEPTK
                     LRPGARLDRFGSVYGSYLAPAGDQYAERALPPQNLNTREAAVPCDYHVYKVTKPFWVWE
                     GSIAPWFEQPGGGRQIKLDPVFLDPSEGQRLNVKWLLEHGYLAAVQP"
     gene            complement(5696..6427)
                     /locus_tag="DKG71_RS38240"
                     /old_locus_tag="DKG71_38240"
     CDS             complement(5696..6427)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058934.1"
                     /locus_tag="DKG71_RS38240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38240"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_109894831.1"
                     /transl_table=11
                     /translation="MRFTSETSSDGVSEQIFTLGEIPGALWTPEGAAGTRPLVLMGHGG
                     GQHKKAPGIVARARRLVAECDFAVATVDVPGHGDQPKDEEYDRIATENQARVAAGEELA
                     PLIAGFQALVARRTVPEWRAVLDAVQGLAYVGAGPVGYWGVSLGCGLGVPFVAAEPRVR
                     AAVLGLGGAQASAETAARITVPVEFLLQWDDERVPRAEGLALFDALASDEKTLHANPGK
                     HGEIPACELDSMLRFFTRHLG"
     misc_feature    complement(6507..6520)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.1"
                     /tool="antismash"
     gene            6630..7247
                     /locus_tag="DKG71_RS38245"
                     /old_locus_tag="DKG71_38245"
     CDS             6630..7247
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973084.1"
                     /locus_tag="DKG71_RS38245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38245"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_109894833.1"
                     /transl_table=11
                     /translation="MRITKYTHSCVRLERPGGGTLVIDPGIWSEARALHGADAILVTHE
                     HADHVDVLRLKGLGAPVYAPRGADFGGLLDVIEVEPGEEFSAAGFAVTAHGGRHARIYG
                     ELPDCANLGYLIDERLYHPGDSLHVPDAPVETLFVPLQASWLRTSEAIDFVRAVKPERA
                     YGIHDAQINERGLHSVNGWLDEEAGGCYSWLPPGAPSPCSER"
     gene            complement(7350..7823)
                     /locus_tag="DKG71_RS38250"
                     /old_locus_tag="DKG71_38250"
     CDS             complement(7350..7823)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669584.1"
                     /locus_tag="DKG71_RS38250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38250"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_018088658.1"
                     /transl_table=11
                     /translation="MTDTEPPLAPDDLAHRLTEVFDLVGPLYRRVQRKVEQSAPIEGLS
                     VGVRAVLDLLRDNGPMTVPQMGRAQALSRQFVQRMVNDAAARQLVEITPNPAHQRSSLI
                     RLTDEGRAAITAVLAREHALLRQVEGDLTDADVTACVQVLTKMLALFDHVEVG"
     gene            7900..8721
                     /locus_tag="DKG71_RS38255"
                     /old_locus_tag="DKG71_38255"
     CDS             7900..8721
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (26-257). E-value:
                     7.9e-28. Score: 89.6. Matches aSDomain:
                     nrpspksdomains_DKG71_RS38255_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979827.1"
                     /locus_tag="DKG71_RS38255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38255"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_204166000.1"
                     /sec_met_domain="PF00561 (E-value: 7.2e-21, bitscore: 73.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.7e-20, bitscore:
                     73.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDLEMCSFETGDGHLAYRDIGAGRPVVLLHGGFLDSGMWDDQL
                     PALTRNHRVIAPDARGHGASSNATRAFRHTDDLAALLRHLDVGPAVLVGLSMGAATAVD
                     TALEHPGLVRALVVSGAGTSEPEFHDPWVKDVMAEQARALAAGDIEGWIDAFMLFAPGP
                     HRTLDDVDQDVVRRLREMTARTLAKHTGTEPDWQVPVADTWARAAKITVPVLALSGAID
                     APDQIGMGERLVHSVTHGRATTIDGTAHYPNMERPEAFNESLGEFLRTVGA"
     aSDomain        7978..8670
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DKG71_RS38255_Abhydrolase_1.1"
                     /evalue="7.90E-28"
                     /label="DKG71_RS38255_Abhydrolase_1.1"
                     /locus_tag="DKG71_RS38255"
                     /protein_end="257"
                     /protein_start="26"
                     /score="89.6"
                     /tool="antismash"
                     /translation="PVVLLHGGFLDSGMWDDQLPALTRNHRVIAPDARGHGASSNATRA
                     FRHTDDLAALLRHLDVGPAVLVGLSMGAATAVDTALEHPGLVRALVVSGAGTSEPEFHD
                     PWVKDVMAEQARALAAGDIEGWIDAFMLFAPGPHRTLDDVDQDVVRRLREMTARTLAKH
                     TGTEPDWQVPVADTWARAAKITVPVLALSGAIDAPDQIGMGERLVHSVTHGRATTIDGT
                     AHYPNMERP"
     misc_feature    8032..8034
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       8161..8217
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DKG71_RS38255_0001"
                     /evalue="2.10E-03"
                     /label="NRPS-te1"
                     /locus_tag="DKG71_RS38255"
                     /protein_end="106"
                     /protein_start="87"
                     /score="10.7"
                     /tool="antismash"
                     /translation="GPAVLVGLSMGAATAVDTA"
     gene            8803..9576
                     /locus_tag="DKG71_RS38260"
                     /old_locus_tag="DKG71_38260"
     CDS             8803..9576
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088660.1"
                     /locus_tag="DKG71_RS38260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38260"
                     /product="DUF72 domain-containing protein"
                     /protein_id="WP_109896743.1"
                     /transl_table=11
                     /translation="MTVLVGTSGWQYKDWREVLYPQDRPQRLWLEEYARHFATVESNAA
                     FYRLPEEKTFADWRDRTPDGFVMAVKASRYLTHIKRLRDPDEPVGRLMSRAAALGPRLG
                     PVLLQLPPTLRVDAGLLDDCLGCFPAGTRVAVEPRHPSWWTAEIRTVLERRGAALCWAD
                     RGSRPVTPLWRTADWGYLRFHEGRAEPWPRYGGQALTTWARRIADTWPDRADVYTYFNN
                     DPGGAAVRDATRFARAVAAAGRSVSRAPSGRGAAR"
     gene            9647..9931
                     /locus_tag="DKG71_RS38265"
                     /old_locus_tag="DKG71_38265"
     CDS             9647..9931
                     /EC_number="3.6.1.7"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088661.1"
                     /locus_tag="DKG71_RS38265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38265"
                     /product="acylphosphatase"
                     /protein_id="WP_204166001.1"
                     /transl_table=11
                     /translation="MIRRRVVVSGEVHGVFFRDTCRRTADRLGVAGWVRNLPDGTVEAV
                     CEGEPGRVQKLVDWAHQGPPLATVDAVSVREEEPEGLTGFEIRPTPGEF"
     gene            complement(10001..11404)
                     /locus_tag="DKG71_RS38270"
                     /old_locus_tag="DKG71_38270"
     CDS             complement(10001..11404)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="DKG71_RS38270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38270"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_109894837.1"
                     /sec_met_domain="LANC_like (E-value: 5.7e-37, bitscore:
                     126.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPLALCDAASDLAHRVADLLSSPEQVAGTAHEAFAALPPELLQ
                     PAWQPASLLLGHPGIALLHTRCARNDARYAAVGHAHLAAAVAATTDAGPAAVGDLLLPA
                     RLHAQEHGGYTRLLARSAEVHAGYVRAHVARLAARRQERGPGLAAGDYDAISGLAGEGR
                     GLLLAADHGDERCARALHDVLGFLVGMTHPLPSPAGDGSRMPGWWCAPDRYLVPRDRAE
                     FPNGDFNVGVAHGICGPLALMSLAYRSGHRVPGMPDALRRMADWVVSLGYPDELGTQWP
                     GRVAHPEATGEPSQPSRQRRRSREAGARSRPGWCYGTSGIAWTLYLAGRALGDRRLTDL
                     SEDAVSGLVRRPYGAAVSADPGFCHGRAGILHTVSRMAVATGRTEWWAAADELARELVA
                     ECDTRTPFGYRQVLPPSPLSEPAPHRVHNPGLLDGAAGIALVLADYADARRGVALDEVN
                     GWDAAFLMG"
     gene            complement(11401..14637)
                     /locus_tag="DKG71_RS38275"
                     /old_locus_tag="DKG71_38275"
     CDS             complement(11401..14637)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="DKG71_RS38275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38275"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_162597024.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 8.7e-169,
                     bitscore: 561.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 6.8e-12,
                     bitscore: 44.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.2e-36, bitscore:
                     125.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRHGCGVLREVVPQHPAPTSAEAMAGERGGADVSGTCEVAFECG
                     TVALVRAAALPLPPDDPPARQPDEALPEEERLRRHIARLAADPRLMEAVSLASASLATE
                     ADRVVAGERLRLKSLRRLAISLTKYRSRMSHRPTPFGLFAGVGLAGFGPAPAREPVGGG
                     RSVTRPDAAWLDGVLETLREVPAVLERSRLTANNLHTVRNGRLVLVDHHDRTGERQLAG
                     SVRHTRVVRHLLAAARATPFPRLVEEGKRQFPQAPEGAVESSIVQLVRGHFLLTDLTPP
                     PDCTAPLDHVRDRLHGVDHPAAHELRATHAELLALDAAPPGGRRARLTAVSALMRALQP
                     AADVLQTDLSLDVRLTLPEEVAREAARAATVLWRTSPVHRGNPHLRDYHLAFLERYGTD
                     RPVPVLELLDEARGLGLPRPYREPTALPSPEPGERDRLLGELLMDAARRGAREVVLDEE
                     TVRALEPAERGPAPLSMEVGAELVAPDWEALCDGDFHLVLAPQAVSPLAGAMFSRFAPV
                     LGRPGARIQELALHAEQSAPDGEIPACVAYRPRVARSGNVSAVPQWLSHRLPLGVGPAA
                     AETAHDLRLEHLAVHADTDGLRLVDGPTGRRVRPLSYSMLHPGNGHLPHVARFLLELGQ
                     EGRSFCAPWSWGSWASAPALPRVRHGRTVLSPAQWLPDRALRAAAGQRDEEWGAQVGQW
                     RRRWGVPRRVLLTKADHRVAVDLDDPLQLLVLRDEVRRATGLVLVERFGGQEERQWFQG
                     PEGSHSAEFVFPVFARPAGRSAAQGTRQAPPVTVPAPLLTGGPGSGRGTRTHLPGGEWL
                     YAKIYVPRARQPEVLARHLGALTDPELLRRAGADLWFFLRYEDPVPHIRLRFHGKPDSL
                     WPVLLPVLHSWARARAEAGLLGNVILDTYEPEVERYGGPAALGHAERVFHADSESVVTL
                     LAMAPDQLDELSLPAALGILDILTRLGTPNEALSWLSSPSVLERRGEVPRARKQEVAAL
                     LDAHARPRPPAAADGWGVGWSTRGPALAGLREVLSAGATDPDRMARIALSLTHMHCNRL
                     LGPLREQELTAHVTAREALALWLGRKRNNR"
     aSDomain        complement(13795..14058)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DKG71_RS38275_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.30E-14"
                     /identifier="RREFam001.1"
                     /label="DKG71_RS38275"
                     /locus_tag="DKG71_RS38275"
                     /protein_end="281"
                     /protein_start="193"
                     /score="44.8"
                     /tool="antismash"
                     /translation="TANNLHTVRNGRLVLVDHHDRTGERQLAGSVRHTRVVRHLLAAAR
                     ATPFPRLVEEGKRQFPQAPEGAVESSIVQLVRGHFLLTDLTPP"
     gene            complement(14631..14771)
                     /locus_tag="DKG71_RS43090"
     CDS             complement(14631..14771)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DKG71_RS43090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162597025.1"
                     /transl_table=11
                     /translation="MENVAISVDEFDLDLDMDLMEPAETAAKAQDPQLMTQVCSPTTWP
                     C"
     gene            complement(14979..16028)
                     /locus_tag="DKG71_RS38280"
                     /old_locus_tag="DKG71_38280"
     CDS             complement(14979..16028)
                     /EC_number="1.3.1.98"
                     /GO_function="GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF010478.0"
                     /locus_tag="DKG71_RS38280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38280"
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="WP_275427327.1"
                     /transl_table=11
                     /translation="MQEKQEHMRVTHEAPLAPMTTLGIGGPAGVLFELFDPADFPEFVT
                     LADASPGEPVCLGAGSNVVVSDAGCEGAVLRMSTKGLRMTGSTADGRVLVEVQAGHPLG
                     DLVDTTIAEGLTGLEMLVGIPGTTGATPVQNVGAYGQETADCLVEVTAWDWELRRVVTL
                     DAAACGLGHRTSVFKHSRRWTLLTLVFALRRSALSAPVTYRTVAGVLDVPVGSSVPLEE
                     VAQAVLTVRRSKGMVLGCSGTDDRSVGSVFLSPEISAAQADGLRARHAPVNRFPDGSTR
                     VSASWLIRQAGFELGTPVVTGVRLSSLHYTLVADEGATAAGFTRAIELVRQEVLRRTGV
                     RLTSELDFL"
     gene            complement(16198..17505)
                     /locus_tag="DKG71_RS38285"
                     /old_locus_tag="DKG71_38285"
     CDS             complement(16198..17505)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006601817.1"
                     /locus_tag="DKG71_RS38285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38285"
                     /product="hypothetical protein"
                     /protein_id="WP_109894843.1"
                     /transl_table=11
                     /translation="MNDTSVLATCLARLSWPPERLAREINRRCGNGTISSKAPYNWLKG
                     SCPRRRLPYIIAKILSDHLGEPVTVEALWPEHFPSTVPAFRPAPAQQRLAPPVQRPAAL
                     DPLTASVDWLVADEALPPPSRSRGDEVPGVAVEMLTVRIQQLRQLDDSGSSGLVLDWAL
                     QDLQWAERLAAKYSYDASTGRRLHRIIAELGQLTAWLTADQGMDALSSSRFLSALDAAR
                     AAGDRPLAAYIISCMSYRAGWAGRAEEALRLIRIARKGSAQEDMGIGQALLATREARAH
                     ASLGDEAACQRALEDAAELSRTGRPSAEPPWAYWLTPAVMVADAGRAWLELGRPKRAEE
                     HLTRGIDMLQGSQPRNLLLHSASLAEARLARCELDGAAEAATDALALAENVSSQRAHAR
                     LMALRRRFVRYDSAVARDIVQRADDLLTAGQAQAAG"
     misc_feature    complement(17485..17487)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17715..17730)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.52"
                     /tool="antismash"
     misc_feature    17735..17751
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 24.03"
                     /tool="antismash"
     misc_feature    complement(17736..17750)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.38"
                     /tool="antismash"
     gene            complement(17790..19076)
                     /locus_tag="DKG71_RS38290"
                     /old_locus_tag="DKG71_38290"
     CDS             complement(17790..19076)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980474.1"
                     /locus_tag="DKG71_RS38290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38290"
                     /product="MFS transporter"
                     /protein_id="WP_018088667.1"
                     /transl_table=11
                     /translation="MEPRGRTRWAIGGLLAGGIVVNFLDRTAISVASSSIADEFGLDLQ
                     QLGVVLSAFTWSYCLVQLPAGMLVDILGVSRLTRIASALWAVAGLLTAVAGGVGPIILA
                     RLLLGVAEGPSMVGASKATAAWFPVSERGMATALFDGATKLANMVSFPVLAFVMSEWGW
                     RAGFLFSAAVSLLFTVVWWWGYRDPSEYRSLRPAEREFILRGGARDTDRGGLRQFRSAL
                     RSGRVWTVACGFACYGYTINIVLTWMPEFLQREFHVRLLQSGFYSMVPWAIATVAELAV
                     GGWLVDRLIRRGRDPWVVRRTVLTCGLALGGTIGAAGSAGSPAVAVCWMSVSLAGLAIA
                     APVAWALPGLLAPPGAVGAVSGLMNFLNTAATAGGVLLTGWLAQMTGSFDAPFLFAVAV
                     LAVGVALYWRALRPVPVREQDPARQLHKV"
     misc_feature    complement(18825..18827)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(18888..18890)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19384..20397)
                     /locus_tag="DKG71_RS38295"
                     /old_locus_tag="DKG71_38295"
     CDS             complement(19384..20397)
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088668.1"
                     /locus_tag="DKG71_RS38295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38295"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_109894845.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 1.7e-59, bitscore:
                     199.0, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAPQSAPTPEPHPVKNLLAVVSPHVGGRTAGAALAGLFPGQAR
                     VTVVESADEDPAALRDAHLLITGLSPVTADHLAAAPHLELVQCASHGFDYVDLDAARER
                     GVPVCNIGSSGAEKQNVAEQTFALMLALAKQLVPAHTALVEADWALPRLQQSLTELSGK
                     TLGIIGLGHIGEEVARRAVAFDMTVVYTGPRPAGPETEARLGGARHLSLDDLLRTADYV
                     TLHAPLNDRTRHLLDAERLALLKPTAFVINTARGALIDQDALADALEAGTLAGAGLDVF
                     DPEPPTAALRLLKAPNVVLSPHVAGVTRETLVRIALAAVQNVIGHLEGKPLRDIVS"
     gene            complement(20394..21563)
                     /locus_tag="DKG71_RS38300"
                     /old_locus_tag="DKG71_38300"
     CDS             complement(20394..21563)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389355.1"
                     /locus_tag="DKG71_RS38300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38300"
                     /product="lactate 2-monooxygenase"
                     /protein_id="WP_109894847.1"
                     /transl_table=11
                     /translation="MAKHWADFQYEIYLHGMTGAVPRLPTDLTRLERLAEQRLGPGPVG
                     YVAGSAGTGSTADANRAALDRRRIVPRMLRDVHERDLSVEVCGRALPAPLALAPVGVLS
                     IMHPDAESAAARAAAAQGLPYILSSASSTPMEQVAEAMGDGERWFQLYWAKDREVTRSF
                     LHRAKAAGYTALFVTLDTPLLAWRPRDLDQAYLPFLHGVGTANYFSDPAFRAGLAKPVH
                     EDPNAAVRHFVGMFADPAKTWPDLAFLRENWDGPIVLKGVLHPDDALRAAEAGVDGVVV
                     SNHGGRQVAGSVAAADALPRVAEAAAGRLTVLFDSGIRTGDDIFKALALGAKSVLVGRP
                     YAYGLGLDGQAGVEHVLRCLLAEFDLTLALSGHSRPTTPTADDLIEESV"
     misc_feature    21535..21553
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.3"
                     /tool="antismash"
     gene            21675..22841
                     /locus_tag="DKG71_RS38305"
                     /old_locus_tag="DKG71_38305"
     CDS             21675..22841
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037653.4"
                     /locus_tag="DKG71_RS38305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38305"
                     /product="PucR family transcriptional regulator"
                     /protein_id="WP_109894849.1"
                     /transl_table=11
                     /translation="MTEERERIRQQLIADPRAVATIVAAVREQVPAYAALDDSRLHEVR
                     AIAAWALDRLLHLWVTDGALTPADLRRFRGIAAARAADGRPMPAVLRAYRVAATVLTDE
                     IAAAAPPLGAPDAFALTRMALTTLDTLAEEMATAYTATSEDLAGDRDRALRLLLDDLIT
                     GRHASIGALTDRAARLGVQLPDHYCLLVAEPTEVGGPAVTQEAALGLLAALNGPGGAST
                     FPATVRGSRLVLLLPAAAGGRAPEVLHERGLRGCAISGESLDRIAVAYRLAADALDTAP
                     AHAHHPARVLTDGDAQVLALLGGRPAATPEHLSRLILGPLVQPGRHHLMEALTTYLDTG
                     SANAAARRLGLHPQSLRYRLRRISDLTERDPRDPWQRLTLDIARTIAH"
     gene            complement(22885..23790)
                     /locus_tag="DKG71_RS38310"
                     /old_locus_tag="DKG71_38310"
     CDS             complement(22885..23790)
                     /GO_function="GO:0016702 - oxidoreductase activity, acting
                     on single donors with incorporation of molecular oxygen,
                     incorporation of two atoms of oxygen [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015043.4"
                     /locus_tag="DKG71_RS38310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38310"
                     /product="carotenoid oxygenase family protein"
                     /protein_id="WP_275427301.1"
                     /transl_table=11
                     /translation="MVHGVRIRDGRAEWYRNRWVRSTAVADRLGEPRRGTPVDELMDIS
                     PNVRVVGLAGRTFALIEGGIRPYELTYDLDTIGPCALGATPQGYSANAHSLFDPRTREL
                     HSLAFRYGSDQVQHIVMDETGVVLRATTVEVPGNPYMHDFALTDRHVLLFDSPVVFSAA
                     HLPTGIPFVWDGNRPARVGVMPRAGGAVRWFEVAPSLVGHTLNAYEDGSEVVIDVVRHP
                     EGFDIRDVGTSRPTLDRWTVDLTAVFDPERGATDLLLSALDFTGEPIARIHLPVRVPLG
                     LHGSWVPGDEREVPRYALAG"
     gene            complement(<23877..23957)
                     /locus_tag="DKG71_RS45360"
                     /pseudo=""
     CDS             complement(<23877..23957)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015043.4"
                     /locus_tag="DKG71_RS45360"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSRGGAFAPVTEEITAYDLPVTGRLPA"
     misc_feature    complement(23883..23885)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(23970..24332)
                     /locus_tag="DKG71_RS38315"
                     /old_locus_tag="DKG71_38315"
     CDS             complement(23970..24332)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024701.4"
                     /locus_tag="DKG71_RS38315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_38315"
                     /product="TetR-like C-terminal domain-containing protein"
                     /protein_id="WP_239472172.1"
                     /transl_table=11
                     /translation="MTRLSNLGTAYREHALAEPAYYRVMFEQAVAETAFEASTAAVTAC
                     IDSGAFRPGDAQEMAKILWAASHGAVSLEIAGHFPPDTAAHRYETLMTAVAQAFSARPA
                     TATADSASPTEEGQTS"
     misc_feature    complement(24516..24535)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 23.87"
                     /tool="antismash"
ORIGIN
        1 tgcccgagcc gctctccgaa cagggctggc agatcgtcga cgagttcaac cgcgcgttct
       61 ccgacgcccc ggagagcggg tacgtcgccc ccgtccacat cgccaccgcc gccaacagcg
      121 gcggtgcact gtcctgggac tccgagggct accgccaggc gtaccgcaag atctggggcg
      181 attgaggtca ccggccggcg cggattccag gccgtcggtc atgtcccgtc ggcggatggc
      241 cacttgggga atggtcaccg ggaatgctca ccgggaatgc tcaccgggga tggttacttg
      301 gggacggtcg aggccacgtc gtcgagggtg gcgtcggtga ccagtccggt gtcctccagt
      361 acctccatgt ggtcctggac ggtgttgttg gtctgggtcg ccagccgccg gatcagggag
      421 ttcttggtgg tggcgcgcac ctcgccgatg gtgatgaaga tcttgccgtg ggaagcgcgg
      481 agcaggtcca cgaagatctg gtcgaactcc ttgccccggg ccttctccaa ctggtccacc
      541 cagccctgtt gttcggcggt ggcctcgtcg gggatgggca cgttcagcgc ctcggagtcc
      601 tcacgggcca gctggtcgag cttgctgtgc ccttcgagca gatgcatacc ggcgcgcttg
      661 atggcctcgc tggatgcgtg cgtctgggcg agccggcccg ccggcatctc ccacagcccc
      721 gcttgccgga ccttggtgag gaaggtcttg tccagggcac cgaccgcgcc cgtattgcct
      781 cccccaggac cggccagggg cgctctcgcg gcaggggcat gggcagaggc cggctcgtcg
      841 gcggagctgt tccgttgtga gagccacacg gatacggtcg cgatggcagc gatgagagcg
      901 accgtggcgg ctatcagacg gccacggctc gatgtgggct gcgatttccg tgcgtgagat
      961 ttcatcatgc ctcctggatt gcgcgcgagg gtcgacggag cgctgtcgcc catggggctg
     1021 ttggggcacg gtcacgctaa ccattgcatt gagcaaagaa gccgattcag cggcgatgct
     1081 caaatccatg gagtggttgg cgacgatgag ctacgatgcc gcgcttcctt cgcacgccca
     1141 ggattccggg tgccactgcc ggaaggtgca agggatggcc ggcgccccag ggagccgcaa
     1201 cgccgagcgc accgcatgga catggctgtc gcacggcccg gttgccggtc cctgcccgtc
     1261 gttgtgcggc gtcccggtgg gcaggccggg agatcagggc ggtagaaata gggaatggtg
     1321 gagcacggag cccccacgag ggccatggat gatgtggatg cggtgacccg ggcggtgctc
     1381 acggcgtcga ggctgctggt tgcggtgtcg gcgcggtcac tcggcgaggc cgaggagcgg
     1441 gtgacgctgc cgcagctgcg gatgctggtg gtcctctcca cccgaggcgc caccaagctc
     1501 gttgccctcg ccgaactgct gcaggtcgct ccctcgaccg cgatgcgcat ggtggaccgg
     1561 ctcatcacgg cgggtttggc acaccgtcag gccaaccccg gcaaccggcg cgagaccttg
     1621 ctccagctca ccgacgaggg gcggcgtacg gtcgaggagg tcaccgcccg ccgccgcgcc
     1681 gagatcagcg ccatcgtcga acgcctaacc cccgagcagc gcgcctcgct catcgaggca
     1741 ctcacggcgt tcaacgaggc gggcggcgaa ccacccgtgg actcacggga ggagacgcac
     1801 ccgctggggt gagccgccac cgggacacgg ccgcccgccg ctcctgggag ctcagcgtga
     1861 cacggggaag gcggcgcgca gaccggaccc gttgacgagg aaagcggttg caccgaggac
     1921 gagggcgcag ccgacctgca tcaggacgaa ccacggcggg agcgcaccgg ggatcatgtc
     1981 gatggcgacg atggcgatcg gcacgacgac cgagatgatg cgcacacgga gataggcccc
     2041 tcgtgctccc cgtgaagcga ggaccgtcag ccagtaggcc accgcggcac tcgcgagcac
     2101 accggccgag cggccccaca tgaacgcggt caccgtgtgt ccggtgctcg cgaggacgac
     2161 gacagtgatg aggaccgcgg cgctcagcgc gccgtaggcc gcgacgagcg ccttcaccct
     2221 gccgaaggct cggtgggggt gcggacggtt gaggtgggcg gtctcggccg tggtgtggct
     2281 ggcggttccc atgtctctct gcgtctcctt ctgcactgat gtggtctggc ccggtgtggc
     2341 ctgacctggt gtcgacgcta gggagcgcat caggggcgcg gtatgcgcct gggcctacgg
     2401 aggggtgggg ccagacctac ttcgcagccg atccgacggt caacgggtgg cgtgcggtgc
     2461 acagtggaac caccaaaccg caccggccgg ttgggcacat tccgggaatc acgggtgcca
     2521 cggccggggt gatgaagcag aaagaggggg gtcatgcgac aggtggtgtc gtggatggcc
     2581 ggcgcctgcg tcgggtttgc gcgtgcgtgc gtggtggtgg ccgtcagcat gctggtcccg
     2641 gccgtgtggg ccgctgccgt ggcggtggcg atccggtggg gggcgggaaa cccgtggtca
     2701 tgggtgccgg tgttggtgct gggcagtgtg ggcacgctcg ccctgtcccg ccccgtctgc
     2761 cggatgttcc gcttcctcgt cgcgacgtgg acagccaccg atattcccgc cgggtatcgg
     2821 cgggccgaac cggtggtgcg catgtccacc ggctactggt ggaacggctt ctcctacgag
     2881 cgcacccgcc gggacgccct cctggaccag cggtggcgga tccggtggag tgattcggcc
     2941 acctggcggg acctgcgctt cacggggatc gcaccgatca ccgcgggcgc gatcgcgtcc
     3001 ctcccgccgg ccggcgtcgc ggtggcgttc ctcgggttcg gccagccgga gctctccgca
     3061 cgccttgtcg gggtgctcgg tctgatcgcg gccgtcgccg gcgccccgta tgcctggcgg
     3121 tccgccgagc cggtggccgt ccgcttcctg cgcgcgtcgc cggcgatggt gctggcggac
     3181 cgggtggcag agctgacggc ccagcgcgcg gacacgacgg tcgcacaggc cgccgagatc
     3241 cgccggatcg agcgggatct gcacgacggg gcgcaggcac gcctggtcgg gctcgggctc
     3301 tctttggcga ccgcggagaa gctgatggaa accgaccccg accaggccaa ggcgctgatg
     3361 cgggaagcac gggccggcgc cgccacgtcc ctgaccgagc tccgcgaact ggtcatgggc
     3421 atcaacccgc cggtgctgaa cgagcgcggg ctcatcgatg ccgtgcgcgc tctggccctg
     3481 gacagcccgc tcgaagcggt ggtcagcgcc gaggttccgc tacgcctgga cccgccgatc
     3541 gagtccgccc tgtacttcgg catcgccgaa ctggtcacca acgcgaccaa gcacgcccgg
     3601 gcgacccggg cacggatctc cctctcccgg gacgacaccg gcaccggcac cggcaccggc
     3661 atcgtcgtcg atgtcgagga cgacggccgg ggcggcgccg atgtgcgggc cggcggcgga
     3721 cttgaggggc tgcgccgccg ccttgcggtc ttcgacggca ccttggagat caccagcccg
     3781 gcaggcggtc cgacccgtgt gaggatgatg gtcccgtgcg catcgttgta gccgaggacc
     3841 tctacctcct gcgcgagggg atggtccgcc tcatcgaggc gtacggacac caggtggtgg
     3901 cgacggcagc caccgggccc gagacgctcg acgcgctgct gacatggcgg ccggatgttg
     3961 ccgtcgtcga catccgtatg ccgccgaccc agtcggacga aggcctgcgg gtggcccttg
     4021 ccgcccgcag cgaacttccc ggactcccga tcttgatcct ttcgcagcac gtcgtacagc
     4081 tctatgcccg cgaactcctg gccgacggcg ccggcggcat cggctacttc ctcaaggaga
     4141 acgtgttcga cgccgatcag ttcatcgatg ccctggaacg ggtcgccggt ggcgggacgg
     4201 ccatggaccc cgccgtcatc gccgcgttgc tgtccagcgg ctcctcgcac cgacgcctcg
     4261 aagggctcac cgaacgcgaa cactccgtgc tcagcctcat ggccgaaggg ctgtccaatc
     4321 aggccatcgg ccggcggctc tacctcagtg acagcgccat cagcaaatac accacctccc
     4381 tgttcggcaa gctcggcatc accgatgacg gcaccgccaa ccgtcgcgtc ctcgccgtcc
     4441 tcacctacct gaacgagccc tgacgtgcct ctcggccccc tgctgcgcga gtgcgacgaa
     4501 ccagccgcta cggagcctca gttgccgccc ccgagtcagg tcagcagccg ccacagatgc
     4561 gcacacgccg cctcttcgtc cagatgccgc gcgatgggcc ggcaggtgcc gcgttcgtag
     4621 gctccggtct cccacgcccc gtccgctgtt ctgcgcagat acaggaaatc ggggggcgtg
     4681 gggacgggtt catggacgcc ttcgatgcgg tagtagccgt cggccactcc cgccgcggtc
     4741 agcgcggtgc gcagctcatg gcggtccact gccgcgctac ggctgtaccg cggcgaggta
     4801 gccgtgctcc agcagccact tcacattcag ccgctgtcct tcgctcgggt cgaggaacac
     4861 cgggtcgagc ttgatctgcc ggccgccgcc gggctgctcg aaccaggggg cgatgctgcc
     4921 ctcccacacc cagaacggct tggtgacctt gtagacgtgg tagtcgcacg gcaccgccgc
     4981 ttcacgggtg ttgaggttct gcggaggcag cgcccgctcg gcgtactggt caccggccgg
     5041 tgccagatag gagccgtata cggatccgaa acggtcgagt cgggctcccg ggcgaagctt
     5101 ggtgggttcc ttgtcgatct cgccgttgac ctcggcgaag ccgtcgttgg gcgggtactt
     5161 ccagctgccg ctgtccgcgg gcccctgcca gtacttcttc aggaaggccg aaggcgacag
     5221 cgccccggtc cgcttccatc cgttcagcag cggtcccacg ggcgcatgcc acttcttcgg
     5281 cagccgcttg gggcccagcc gggcctcgcc ctggaactcc ccggtgcagg gcgcgggccg
     5341 gggtgcggcg gccggacgct gccgttcctg ctggtgcggt gcggcagccg cggccggggc
     5401 cgtcgccatg gccacggcga taccgagggc ggcaagtacc gtgcggacgg tgcgggttcg
     5461 cttcactcag gagtctcctc acgctctgac tgaccggcct gatcggcgag tgccggatca
     5521 ggccgccact tacgcaaggt aatggatcga gcacgatggg tgtgcctgaa tgccgcaaca
     5581 ggtgacatgc accggccggt gcgtgcgctg tgtggaccac gccgaccggt gtgcgctgga
     5641 cgcgccgatc gggaacgggt cccggccggc gcgtcccgga cagcagacgg tgaaatcagc
     5701 cgaggtgccg ggtgaagaac cgcagcatgc tgtccagttc gcatgccggg atctccccgt
     5761 gcttgccggg gttggcgtgc agggtcttct cgtctgaagc caaggcgtcg aacaatgcca
     5821 agccctcggc gcgcggcacc cgttcatcgt cccactgcag caggaactcc accgggaccg
     5881 tgatccgtgc ggcggtctcc gccgatgcct gtgccccgcc caagcccaac accgccgcgc
     5941 ggacccgggg ttcggcagca acgaacggaa cgccgagtcc gcagcccagc gacacacccc
     6001 aataacccac cggaccggca ccgacgtacg cgagcccctg gaccgcgtcc aggaccgccc
     6061 gccattccgg aacggtccgg cgagctacca gcgcctggaa gccggcgatc agcggagcca
     6121 gttcctctcc ggcggccaca cgtgcctggt tctcggtggc gatccggtcg tactcctcat
     6181 ccttcggctg gtcgccgtgg ccgggtacgt ccaccgtcgc caccgcgaaa tcgcactcgg
     6241 ccacgaggcg gcgcgcgcgg gccacgatgc ccggtgcctt cttgtgctgc ccgccgccgt
     6301 gccccatcag aacgagggga cgtgtaccgg cggcaccttc cggcgtccac agcgcgccgg
     6361 gaatctcgcc gagggtgaag atctgttcgg agacaccgtc ggacgacgtc tcagaggtga
     6421 agcgcatagc gtttcaagcc tttcgggatg cctttgcggg cactccctaa gccatgtaag
     6481 agagggagcc ccgacccgtc acagcgttga tcggtctcac ctcctcagtg cgcagcagta
     6541 cacggcggcg ccgaaggtat cacgaagggt ccaccccagt ccgctgccga tggtcgacgc
     6601 ccgcaccccg gacgcctact ctccacggga tgcggataac caagtacacg cattcctgtg
     6661 tccggttgga acgcccaggg ggcgggacgc tggtcatcga tcccggcatc tggagcgagg
     6721 cgcgggcgct gcacggtgcc gacgcgatcc tggtgacgca cgagcatgcc gaccacgtcg
     6781 atgtgctgcg gctcaagggc ctcggcgcgc cggtctatgc acccagaggc gcggacttcg
     6841 gcggtctcct ggacgtcatc gaggtcgagc cgggcgagga gttcagcgcg gcgggcttcg
     6901 ctgtcacggc gcacggcggc cggcacgcgc gtatctacgg tgagctgccg gactgcgcca
     6961 acctcggcta tctgatcgac gagcggctct accaccccgg cgattcgctc catgtgcccg
     7021 acgcgccggt ggagacgctg ttcgtgcccc tgcaggcatc gtggctgcgc acgtccgagg
     7081 ccatcgactt cgtccgggcg gtcaagccgg agcgcgccta cggcatccat gacgcgcaga
     7141 tcaacgagcg gggcctgcac agcgtcaacg gctggctcga cgaggaagcg ggcgggtgtt
     7201 acagctggct gccgccgggc gcaccgtcgc cgtgctcgga gcggtgactg cttgtcggga
     7261 acggtagccg cccgttggga gcccggcggt gaccggtcgc cgcgtgaccc ggccgtgccc
     7321 gggagtgcgg ggcgaagcgc ccgcgctcct cagcccacct ccacgtggtc gaagagcgcg
     7381 agcatcttcg tgagcacctg cacgcacgcc gtgacgtcgg cgtcggtcag atccccctcg
     7441 acctgacgga gcagggcatg ctcacgcgcc agtacggcgg tgatggcggc cctgccctca
     7501 tcggtcagcc ggatcaagga agaccgctga tgggcggggt tcggcgtgat ctcgacaagc
     7561 tgtcgtgccg cggcgtcatt gaccatgcgc tggacgaact gccggctcag cgcctgtgcg
     7621 cggcccatct gcggaacggt catgggtccg ttgtcgcgga gcaggtccag tacggcccgc
     7681 acgccgacgg acagcccctc gatcggtgcg gactgttcga ccttgcgctg tacgcggcgg
     7741 tacaggggcc cgacgaggtc gaacacctcc gtgagccggt gggcgaggtc gtcgggcgcg
     7801 aggggcggtt cggtatcggt catcccacca ggatgacacc ttggttgcca atccccagtc
     7861 agagatggca ccttggttgt catgactgac atggctgaca tgactgatga ccttgagatg
     7921 tgttccttcg agaccgggga cggccacctc gcctaccgcg acatcggtgc cggccggccg
     7981 gtggtcctgc tgcacggcgg cttcctggac agcggcatgt gggacgacca gttaccggcc
     8041 ctcacacgga accaccgggt gatcgccccg gacgcccgcg gccacggcgc ctcctcgaac
     8101 gcgacccgcg cattccggca caccgacgat ctcgccgcgc tgctgcgtca cttggacgtc
     8161 ggccccgcgg tcctcgtcgg gctgtcgatg ggtgcggcca ccgcggtgga caccgcgctg
     8221 gagcaccccg ggctggtgcg cgcgctggtc gtcagcggcg ccgggaccag tgagccggag
     8281 ttccatgacc cctgggtcaa ggacgtcatg gccgagcagg cccgcgccct ggccgccggt
     8341 gacatcgagg gctggatcga cgccttcatg ctgttcgcgc ccggccccca ccgcacactc
     8401 gacgacgtcg accaggacgt cgtacgacga ctgcgggaga tgaccgcacg gacgctcgcc
     8461 aagcacaccg gcaccgaacc ggactggcag gtccccgtgg ccgacacctg ggcgcgggcg
     8521 gcgaagatca ccgttccggt gctggccctc agcggcgcca tcgacgcccc cgaccaaatc
     8581 ggcatggggg aacgcctggt gcacagcgtc acccacggcc gtgccaccac catcgacggc
     8641 accgcgcact accccaacat ggaacgcccg gaggccttca acgagtccct gggggagttt
     8701 ctgcgcaccg taggcgcata ggggggagcc gaggtgcgcg gtagtgcacc ggcgccccgc
     8761 acggctgata tgccgggtcc cgccgcgggc aaggatgcgg tcatgaccgt tctcgtcgga
     8821 acctccggct ggcagtacaa ggactggcgg gaggtcctct acccgcagga ccggccgcag
     8881 cggctgtggc tggaggagta cgcgcggcac ttcgccaccg tcgagagcaa cgccgccttc
     8941 taccggctgc ccgaggagaa gaccttcgcg gactggcggg accggacccc cgacgggttc
     9001 gtgatggccg tgaaggcaag ccgctatctg acccacatca agcggctgcg cgatcccgac
     9061 gagccggtcg ggcggctgat gtcgcgggcc gccgccctcg gcccccggct cgggcccgtc
     9121 ctgctccaac tgccgcccac gctccgggtg gacgccgggt tgctggacga ctgcctcggc
     9181 tgctttcccg ccggcacccg ggtggccgtc gagccccgcc acccgtcgtg gtggaccgcg
     9241 gagatccgta cggtgctgga gcggcggggc gccgcgctgt gctgggcgga ccggggttcc
     9301 cggcccgtga cgcccctgtg gcggaccgcc gactgggggt atctgcgctt ccacgagggc
     9361 cgtgcggaac cctggccgcg ctacggcgga caggcgctca ccacctgggc gcggcggatc
     9421 gccgacacct ggccggaccg ggccgacgtc tacacctact tcaacaacga tccgggcggg
     9481 gcggccgtcc gcgacgccac ccgattcgcc cgggccgtcg cggccgccgg ccgctccgtg
     9541 agccgtgcgc cgtccgggcg tggcgccgcc cggtgaccgt ggggccggga tatatctgcg
     9601 ctcgtaccgg cggggcgagc gaacgaggtg acgaggtgag gcacgggtga tccgcagacg
     9661 ggtggtggtc tccggcgagg tgcacggtgt gttcttccgc gacacctgcc ggcgcacggc
     9721 cgaccggctc ggagtggccg gctgggtgcg gaaccttccg gacgggacgg tggaggccgt
     9781 gtgcgagggg gagcccgggc gggtgcagaa gctggtggac tgggcgcacc aggggccgcc
     9841 cctggccact gtcgacgccg tgtccgtacg ggaggaagag ccggaagggc tgacgggctt
     9901 cgagatccgg ccgacacccg gggaattctg acctggccac gggccccggc cccgggcccc
     9961 ggccccgatg tgtcacgggc cggcaccctg aacgaccgcg tcagcccatg aggaaagccg
    10021 cgtcccagcc gttcacctcg tcgagggcga ctccccggcg ggcgtcggcg tagtcggcca
    10081 gtacgagggc gattccggcg gcgccgtcca gcaggccggg gttgtgcacc cggtgcggtg
    10141 cgggttccga gaggggggag ggcggcagaa cctggcggta gccaaaggga gttcgggtat
    10201 cgcactccgc cacgagctcc cgggcgagtt cgtccgccgc cgcccaccac tcggtccgcc
    10261 cggtggcgac ggccatccgg ctgacggtgt gcaggatgcc cgcccggccg tggcagaagc
    10321 ccgggtcggc ggacacggcc gcaccgtacg ggcggcgcac cagtccgctg accgcgtcct
    10381 cggacaggtc cgtcagccgg cggtcgccga gcgcccgccc ggccagatac agggtccagg
    10441 cgatcccgga ggtcccgtaa caccatcccg gccggctcct cgcacccgct tcccgggacc
    10501 gccggcgctg ccgggacggt tgggaaggct ccccggttgc ctccgggtgg gcgacgcggc
    10561 cgggccactg cgtgcccagc tcgtcggggt agcccaggct caccacccag tcagccatcc
    10621 ggcggagggc gtccggcatc cccggcaccc ggtgtccgga gcggtacgcc agcgacatca
    10681 gggcgagcgg gccgcaaatc ccgtgcgcga caccgacgtt gaagtcgccg ttcgggaact
    10741 ccgcccggtc ccgcgggacg agataccggt cgggggcgca ccaccatccc ggcatccggc
    10801 tgccgtctcc tgccggggac ggcaggggat gcgtcatccc gaccagaaag ccgaggacgt
    10861 cgtggagcgc ccgcgcgcac cgttcgtcgc cgtggtcggc cgccagcagc aggccacggc
    10921 cctcgcccgc caggcccgag atcgcgtcgt aatcgccggc cgccagcccc gggccgcgct
    10981 cctgccgccg ggccgccagc cgggcgacat gggcccggac gtatccggcg tgcacctcgg
    11041 cgctgcgtgc cagcagccgg gtgtatccgc cgtgctcctg ggcgtgcagc cgggcgggca
    11101 gcagcagatc accgaccgcg gccgggccgg cgtcggtggt cgccgcgacg gccgcagcca
    11161 ggtgggcgtg cccgaccgcc gcataccggg cgtcgttccg ggcgcacctg gtgtgcagca
    11221 gcgcgatgcc ggggtgtccc agcagcagcg acgcgggctg ccaggcgggc tgcagcagtt
    11281 ccggcggcag cgcggcgaac gcctcgtggg cggtgccggc cacctgctcc ggtgagctca
    11341 gcagatcggc gacgcggtgg gcgaggtccg acgccgcgtc gcacagcgcg aggggtgcgg
    11401 tcatctgttg ttccgcttcc gtccgagcca cagtgccagc gcctcacggg ccgtcacatg
    11461 tgccgtcagt tcctgttcgc gcagcgggcc gagcagccgg ttgcagtgca tatgggtcag
    11521 gctcagggcg atccgtgcca tccggtcagg gtccgtcgca ccggcggaca gcacctcgcg
    11581 caggccggcc agcgccgggc cacgggtgct ccaccccacg ccccagccgt ccgccgcggc
    11641 cggcggccgg ggccgggcgt gtgcgtccag cagtgcggcg acctcctgct tccgggcccg
    11701 cgggacctct ccccggcgct ccagcaccga cgggctgctg agccagctga gcgcctcgtt
    11761 cggggtgccg aggcgggtga ggatgtcgag gatgcccagc gcggccggca gcgacagctc
    11821 gtccaactgg tcgggggcca tggccagcag cgtgacgacg gactcgctgt cggcgtggaa
    11881 gacgcgctcg gcgtgcccga gggcggccgg cccgccgtac cgctcgacct cgggctcgta
    11941 ggtgtccagg atcacgtttc cgaggagccc cgcctccgca cgcgcccgcg cccaggagtg
    12001 gagcacgggc agcagcaccg gccacaggga gtccggcttg ccgtggaacc gcagccggat
    12061 gtgcgggacg ggatcctcgt aacggaggaa gaaccagagg tcggcgcccg ccctgcgcag
    12121 cagctcgggg tcggtcagcg ccccgaggtg acgggccagc acctccggct ggcgggcccg
    12181 gggcacatag atcttcgcgt agagccactc gccaccgggc agatgagtac gcgtgccgcg
    12241 gccgctgccg gggccacccg tcaggagtgg ggccggcacc gtcacgggag gggcctgccg
    12301 ggtgccctgc gcggcgctcc ggccggcggg ccgggcgaag acggggaaga cgaactcggc
    12361 ggaatgggag ccctcggggc cctggaacca ctgccgttcc tcctggccgc cgaaccgctc
    12421 caccagcacc agaccggtcg cccgccgcac ctcgtcgcgg aggaccagaa gctgcagagg
    12481 gtcgtcgaga tcgaccgcga cgcggtggtc ggccttggtg agcagcaccc gccgggggac
    12541 gccccagcgc cgccgccact gcccgacctg cgcaccccac tcctcgtccc gctggccggc
    12601 cgcggcgcgc agtgcccggt ccggcagcca ctgcgccggg gagagcacgg tccggccgtg
    12661 gcgcacccgc ggcagcgccg gagccgaggc ccagctgccc cagctccacg gcgcgcagaa
    12721 ggaccggccc tcctgcccga gctccagcag gaaccgcgcc acgtgcggaa gatggccgtt
    12781 gcccgggtgg agcatggagt acgacagcgg ccgcaccctg cggccggtcg gtccgtcgac
    12841 gagccgcaga ccgtccgtat ccgcatggac cgccagatgc tccaggcgca gatcgtgcgc
    12901 ggtctccgcc gcggcggggc cgacacccag ggggaggcgg tgggagagcc actgcggaac
    12961 ggcggacaca ttgccggagc gcgccaccct gggccggtag gcgacacagg ccgggatctc
    13021 gccgtccggc gcgctctgct ccgcgtgcag cgccagctcc tgaatccgcg cgcccggccg
    13081 gccgagcacc ggcgcgaacc ggctgaacat cgcccccgcc agcggcgaca ccgcctgagg
    13141 cgcgagcacc agatggaagt ccccgtcaca cagggcctcc cagtccggcg ccaccagctc
    13201 ggctcctacc tccatgctca ggggggccgg tccgcgctcc gccggttcca gggcacgtac
    13261 ggtctcctcg tcgagcacca cttcccgggc gccacggcgg gccgcgtcca tcagcagttc
    13321 gccgaggagc cggtcgcgct ccccgggctc gggggagggc agggcagtgg gctcccggta
    13381 agggcgggga agccccaacc cccgggcctc gtcgagcagt tccagcaccg gcaccgggcg
    13441 gtcggtgccg taccgttcga ggaaggccag gtggtagtcg cgcaggtgcg gattgccgcg
    13501 gtggacggga gaggtccgcc acagcaccgt cgcggcacgg gccgcctccc gggccacttc
    13561 ttccggcagg gtcagccgca cgtccaggga caggtccgtc tgaaggacgt cggccgccgg
    13621 ctggagcgcc cgcatcagcg cggataccgc ggtcagccgg gcccgccggc cgcccggcgg
    13681 cgcggcgtcc agggccagca actccgcgtg tgtggcgcgg agttcatggg ccgccggatg
    13741 gtcgaccccg tgcagccggt cgcgtacgtg gtcgagaggg gcggtgcagt cgggcggcgg
    13801 cgtcaggtcg gtcagcagga agtggccgcg gaccagctgc acgatgctgc tctcgaccgc
    13861 gccttcgggt gcctgcggga actgccgctt cccctcttcc accagccggg gaaagggggt
    13921 ggcacgtgcg gctgccagga ggtgccggac cacccgggtg tggcgcaccg atccagccaa
    13981 ctgccgctct ccggtgcggt catggtggtc gaccagcacc agccggccgt tccgtacggt
    14041 gtgcaggttg ttggccgtga gccgtgaacg ctccagtacg gcagggacct cgcgcagggt
    14101 ctccagaacg ccgtccagcc aggctgcgtc cggccgggtc acgctgcgcc cgccgccgac
    14161 cggttcccgc gcgggcgccg gtccgaatcc ggcgagaccg acccccgcga acaagccgaa
    14221 cggggtgggg cggtgggaca tccgtgagcg gtatttcgtc agcgatatcg cgagacgacg
    14281 cagcgacttg agtctgagcc gttcccccgc gacaacccgg tccgcctccg tcgccaggct
    14341 cgcgctggcc aggctcaccg cctccatgag ccgtgggtcg gcggcgagtc gggcgatgtg
    14401 ccgtcgcagc cgctcttctt cgggcagggc ctcgtcgggc tgccgggccg ggggatcatc
    14461 cggtggcagg gggagggccg cggcccgcac cagagccacc gtcccgcact cgaaggccac
    14521 ctcacacgta ccgctcacgt ccgccccgcc ccgttcccct gccatcgcct cggccgacgt
    14581 gggtgcgggg tgctgcggga cgacctctcg cagcaccccg cacccgtgtc tcagcaaggc
    14641 caggtggtgg gcgagcagac ctgtgtcatg agctgcgggt cctgcgcctt cgcggcggtc
    14701 tcggccggct ccatgaggtc catgtccagg tcgaggtcga attcgtccac gctgatggcg
    14761 acgttctcca tgatcccctc caagaaagat gattcaattc cggagtattt ccggttgttg
    14821 cggcgatatt gcgcaaccgc cgacgtattc catccaaggc cgcggaccgg ggtcaagcac
    14881 gttcgatctt tggctgagga gcaactcccc tgctgcgggc ctgtgttacg ttgcgcccgg
    14941 cctcggccgc caccgccccg cacggccggt gtgccgcctc agaggaagtc gagttcggag
    15001 gtgagccgga cccccgtgcg gcgcagcacc tcctggcgta cgagctcgat cgcccgtgtg
    15061 aaaccggcgg cggtcgcccc ctcatcggcg accagtgtgt agtgcagcga ggaaaggcga
    15121 acgcccgtga cgaccggggt gcccagctcg aaaccggcct gccggatgag ccagctcgca
    15181 ctcacccggg tcgagccgtc ggggaaccgg ttcaccggcg cgtggcgcgc ccgcaggccg
    15241 tcggcctgcg cggcggagat ctcggggctg aggaacacac tgcccaccga tcggtcgtcg
    15301 gtgccgctgc agcccagcac catgcccttg ctccgtcgca cagtgagcac cgcctgggcc
    15361 acctcctcca gcggaacgct gctcccgacc gggacatcga gcacaccggc caccgtccgg
    15421 taggtgaccg gcgcgctcag cgcggaccgg cgcagcgcga agaccagggt cagcagcgtc
    15481 caccggcggg agtgcttgaa gacactggtg cggtggccca gcccgcaggc cgcggcgtcc
    15541 agggtgacca cacggcgcaa ctcccagtcc cacgccgtca cttccaccag gcagtcggcg
    15601 gtctcctgac cgtaggcgcc gacgttctgg accggggtgg cgccggtggt cccggggatg
    15661 cccacgagca tctccagccc cgtgaggccc tcggcgatgg tggtgtcgac caggtcgccg
    15721 aggggatgac cggcctggac ctcgaccagc acccgtccat cggcggtgct cccggtcatg
    15781 cgcaggccct tggtgctcat ccgcagcacg gcgccctcgc atccggcgtc gctgaccacc
    15841 acattgcttc ctgcgccgag acagaccggc tcgccggggg aggcgtcggc cagcgtgacg
    15901 aactcgggga agtccgcggg gtcgaacagc tcgaagagga cccccgccgg tcctccgatg
    15961 cccagcgtgg tcatcggggc gagcggtgcc tcgtgagtga ctcgcatatg ttcctgtttc
    16021 tcctggatgc cgttccgtgt cgaggggtcg tgtcagggga gcgcgcggtg gtgcggccgt
    16081 ccctcagtgt gtgacgggcg gaacgccctg ccgcgatccc gcacgagggg agggggccgg
    16141 tgtcctgctg acggcccggg aagggcacgg cggacgacgg gacaacgcgc acacgcctca
    16201 gcccgccgcc tgcgcctggc ccgccgtcag cagatcgtcg gcccgttgca cgatgtcacg
    16261 cgccaccgca ctgtcgtacc gcacaaagcg ccgccggagc gccatcagcc gcgcgtgggc
    16321 gcgctgcgag ctgacgttct cggccagggc cagcgcgtcc gtggcggcct ccgccgcgcc
    16381 gtcgagctcg cagcgcgcca gtcgcgcctc ggccagcgag gcgctgtgca gcagcagatt
    16441 gcgcggctgg cttccctgga gcatgtcgat cccgcgggtg agatgctcct ccgcccgctt
    16501 gggccgcccc aactccagcc aggcccggcc ggcgtcggcc accatgaccg cgggggtcag
    16561 ccagtacgcc cagggcggct cggccgaggg cctgcccgtc cggctgagct cggcagcgtc
    16621 ctccagggcc cgttgacagg ccgcctcgtc accgagactg gcatgggctc tggcctcgcg
    16681 ggtggccagc agcgcctgtc cgatgcccat gtcctcctgc gccgacccct tgcgggcgat
    16741 acggatcaga cgcagcgcct cctccgcccg gccggcccat ccggcccggt agctcataca
    16801 ggagatgatg tacgcggcga gcggccggtc gccggcggcc cgtgcggcgt ccagcgcgga
    16861 caggaagcgg gagctgctca gcgcgtccat gccctgatct gccgtcagcc aggcggtgag
    16921 ctggccgagt tcggcgatga tgcggtgcag ccgccgtccg gtcgaggcgt cgtaggagta
    16981 cttggcggcc agcctttccg cccactggag gtcctgcagc gcccagtcca gtacgagacc
    17041 gctgctgccg ctgtcgtcca gctgccgcag ctgctggatc ctgacggtca gcatctcgac
    17101 cgcgaccccg gggacctcgt cgccgcgcga ccgcgagggc gggggcagcg cttcgtcggc
    17161 caccagccag tccaccgacg cggtgagcgg atcgagggcg gccggccgct ggacgggcgg
    17221 cgcgagacgc tgctgagcgg gggccggccg gaacgccggg accgtggacg ggaagtgctc
    17281 gggccacaac gcctcgaccg tgaccggctc gccgaggtgg tcggacagga tcttggcgat
    17341 gatgtacggc agccggcgcc gggggcagga gcccttcagc cagttgtacg gggccttgct
    17401 gctgatggtg ccgttgccgc agcgcctgtt gatctcacgg gccagccgct ccggtggcca
    17461 ggacaatcgc gccagacagg tcgctaacac agacgtatcg ttcatcggcg gagaacctcg
    17521 gccgcggcgg cgctcgatgc gggaaaagtg gtgtccgggg caggaccggt cagctccggc
    17581 gactgccgga ggtgctccgg agccgggtcg ggtgggagcg gaatcggacc gatggtctcc
    17641 atagccgctt tccacgcccc ctgccgccaa ctgcccagcc atactaggga ttcccgggag
    17701 ccggacagcg aatctgtgat gactgacaca gctcttgcac acgatgtgca agtaccggag
    17761 ccgatcatat ggcgacgcaa tgcggggcct cagaccttgt gcagttgccg ggccggatcc
    17821 tgctcccgca cgggtaccgg gcgcagcgcc ctccagtaga gcgcgacccc gaccgccagc
    17881 acggccaccg cgaacaggaa gggcgcgtcg aacgacccgg tcatctgcgc cagccagccg
    17941 gtgagcagca caccgcccgc ggtggccgcc gtattgagaa agttcatcag cccgctgacc
    18001 gcccccaccg ctcccggcgg tgcgagcagt ccgggcagcg cccaggcgac cggtgcggcg
    18061 atggccagcc ccgccagcga gacggacatc cagcagaccg cgacggcggg tgatccggcg
    18121 ctccccgcgg cgccgatcgt gccgcccagc gccagcccgc aggtcagcac ggtcctgcgg
    18181 accacccacg ggtcgcggcc ccggcggatc agccggtcca ccagccagcc cccgacggcg
    18241 agttcggcga ccgtcgcgat cgcccagggg accatcgagt agaagccgga ctgcagcagc
    18301 cgcacatgga actcccgctg aaggaactcg ggcatccagg tcagcacgat gttgatggtg
    18361 tagccgtaac aggcgaaacc gcaggccacg gtccagaccc tgccggagcg cagggccgag
    18421 cggaactgcc gcagcccgcc tcggtcggtg tcccgtgccc cgccccggag gatgaactcc
    18481 cgctccgccg ggcgcagtga gcggtactcg gacgggtccc ggtagcccca ccaccacacg
    18541 acggtgaaca gcagactgac cgcggcgctg aacaggaacc cggcccgcca gccccactcg
    18601 ctcatcacga acgccagcac cgggaacgac accatgttgg ccagcttggt ggcgccgtcg
    18661 aacagcgccg tcgccatccc gcgctcactg acggggaacc acgccgcggt cgccttggag
    18721 gccccgacca tcgagggacc ctcggccacc ccgagcagca gccgcgccag gatgatgggg
    18781 ccgaccccgc cggccaccgc ggtgagcagg cccgcaacgg cccataacgc ggaggcgatc
    18841 cgggtgagcc gcgagacgcc caggatgtcc acgagcatgc cggcgggtaa ctgcaccaga
    18901 cagtacgacc aggtgaaggc cgagaggacc acaccgagtt gctggaggtc cagcccgaac
    18961 tcgtcggcga tcgaggagct cgccaccgat atcgccgtac ggtcaaggaa gttgacaacg
    19021 ataccgccgg cgagcagtcc gccgatcgcc caacgggtgc gtccacgggg ttccacgagc
    19081 gtgcgccagc ctttcctggt gagccttgcc tgcgcccccg ggcacccgtc ggcgggcacc
    19141 gcttgagggt gcccgccgac gggtggcgag gagcgcatcg gagccgatgc cgggcggacg
    19201 ctactcctgt tgccggggcg gcagccgtcg aaagtgtcga gaaatggcgg tggcgcgcca
    19261 ggaacgcgcc accgcaccgc accgctcctg tgttcgggcc cgctgtccga cgcccggaac
    19321 aatggctgaa attcaggaag gagcacgcac ccgcgccccg ccgcggcgag ggtgccgttg
    19381 ccgttacgac acgatgtccc gcagcggctt gccctccaga tggccgatga cgttctgcac
    19441 ggccgccagg gcgatgcgga ccagggtctc gcgggtgacg cccgcgacgt gcggggagag
    19501 gaccacgttc ggggccttga gcaggcgcag cgcggccgtg ggcggttcgg ggtcgaagac
    19561 gtcgaggccg gccccggcga gggtgcccgc ctccagggcg tccgcgaggg cgtcctggtc
    19621 gatgagggcg ccgcgtgcgg tgttgatgac gaacgcggtg ggcttgagga gggcgagccg
    19681 ctccgcgtcg aggaggtggc gggtccggtc gttgagcggg gcgtgcaggg tgacgtagtc
    19741 ggcggtgcgg agcaggtcgt cgaggctcag atggcgggcg ccgccgaggc gggcctcggt
    19801 ctccggtccg gcgggcctcg gccccgtata gacgacggtc atgtcgaacg cgacggcgcg
    19861 gcgcgccact tcctcgccga tatggccgag gccgatgatg ccgagggtct tgccggacag
    19921 ttcggtcagc gactgctgga ggcgtggcag cgcccagtcg gcctcgacga gggccgtgtg
    19981 ggccgggacc agctgcttgg cgagggcgag catgagagcg aaggtctgct ccgccacatt
    20041 ctgcttctcc gcaccgctgg agccgatgtt gcagaccggg acgccccgct cgcgggccgc
    20101 gtccaggtcg acgtagtcga agccgtggct ggcgcactgg acgagctcca gatgcggtgc
    20161 ggcggcgaga tggtccgcgg tgaccgggct cagaccggtg atcaggaggt gggcgtcgcg
    20221 cagcgccgcc gggtcctcgt cggccgactc gacgacggtg acccgggcct ggccggggaa
    20281 gaggccggcc agcgccgcac cggcggtacg gccgccgaca tgcggcgaga cgacggcgag
    20341 caggttcttc acggggtgcg gctccggggt gggggccgac tgcggcgcgg tggtcatacg
    20401 gattcctcga tgaggtcgtc ggcggtcgga gtggtggggc gggagtgccc ggacagcgcg
    20461 agggtgaggt cgaactcggc gagcagacag cgcagcacat gctcgacacc cgcctggccg
    20521 tcgaggccga gcccgtaggc gtagggccgc cccaccagca ccgacttcgc gcccagggcg
    20581 agcgccttga agatgtcgtc gccggtgcgg ataccgctgt cgaagaggac ggtgagccgg
    20641 ccggcggccg cctcggcgac ccggggcagc gcatcggcgg cggccacgga gcccgccacc
    20701 tggcggccgc cgtggttgga gacgaccaca ccgtccacac cggcttcggc ggcccgcagc
    20761 gcgtcatccg ggtgcagaac gcctttgagc acgatcgggc cgtcccagtt ctcccgcagg
    20821 aacgccaggt ccggccaggt tttggcgggg tcggcgaaca tccccacgaa gtgccggacc
    20881 gccgcgttcg ggtcctcgtg gaccggtttg gcgagccctg cccggaacgc ggggtcgctg
    20941 aagtagttgg ccgtgcccac gccgtgcagg aacggcagat aggcctggtc gagatcgcgc
    21001 ggtcgccagg cgaggagcgg ggtgtcgagc gtgacgaaca gcgcggtgta gcccgccgcc
    21061 ttcgcccggt gcagaaaact cctggtgacc tcgcggtcct tcgcccagta cagctggaac
    21121 caccgctccc cgtcacccat cgcctcggcg acctgctcca tgggcgtgct ggaagcggag
    21181 gacaggatgt acggcaggcc ctgcgccgcg gcggcccgcg cggcggcgga ctccgcgtcc
    21241 gggtgcatga tcgacagcac gccgaccggc gccagcgcga gcggcgcggg cagcgcacgg
    21301 ccgcacacct ccacggacag gtcgcgttcg tgcacatcgc ggagcatccg cgggacgatc
    21361 cggcggcggt ccagtgcggc ccggttggcg tccgcggtgc tgccggtgcc cgcgctgccc
    21421 gccacgtagc cgaccgggcc ggggccgaga cgctgctcgg cgagccgctc cagccgggtc
    21481 agatccgtcg gcagccgcgg tacggcgccc gtcatgccgt ggagatagat ctcgtactgg
    21541 aagtccgccc agtgcttcgc catccgtact cccgcctctc gtcgctgaga ctgcgtgctc
    21601 acccgagatc ctggcgacag tgacaagacc cgtccaccgc gctgcgcaca acacgcgggt
    21661 ggaatcatca ccctgtgaca gaggaacggg agcgcatccg gcagcagctg atcgctgacc
    21721 cacgggccgt cgcgacgatc gtcgccgccg tgcgcgagca ggtaccggcc tacgccgcgc
    21781 tcgacgacag ccggctgcac gaggtacgtg ccatcgccgc ctgggcactg gaccggctgc
    21841 tccatctctg ggtcaccgac ggcgcactca ccccggccga tctccggcgg ttccgcggga
    21901 tcgcggcggc gcgggccgcg gacggccgcc cgatgccggc ggtcctgcgg gcctaccggg
    21961 tcgcggcgac ggttctcacg gacgagatcg cggccgccgc gcccccgctg ggcgcaccgg
    22021 acgccttcgc gctcacacgc atggcgctga ccaccctcga cacgctcgcc gaggagatgg
    22081 ccacggcgta caccgccacc agcgaggacc tcgccgggga ccgcgaccgg gcactgcggc
    22141 tgctcctcga cgacctgatc accggccggc acgcctccat cggggcactg accgaccggg
    22201 ccgcacggct gggagtccaa ctccccgacc attactgcct gttggtggca gagcccacgg
    22261 aggtgggcgg ccccgccgtg acccaggaag ccgccctcgg gctcctcgcc gcgctcaacg
    22321 gtcccggcgg tgcgagcacc ttcccggcga cggtccgcgg ctcgcgcctc gtcctgctgc
    22381 tgcccgccgc ggccggcggg cgggcgccgg aggtcctgca cgagcggggc ctgcgcggct
    22441 gtgcgatctc tggggagagc ctggaccgga tcgccgtcgc ctaccgtctc gcggccgacg
    22501 ccctggacac ggcgcccgca cacgcccacc atcccgcgcg ggtgctgacg gacggggacg
    22561 cccaggtact ggcgctgctc ggcggccgcc ccgccgccac tcccgaacac ctcagccgtc
    22621 tgatcctcgg ccccctcgtc cagcccggcc gccaccacct catggaggcg ctcaccacct
    22681 acctcgacac gggctccgcg aacgccgccg cccgcaggct cggcctccac ccccagtcgc
    22741 tgcgctaccg tctgcgccgc atcagcgacc tcaccgagcg cgacccacgc gacccctggc
    22801 agcgcctcac cctggacatc gcccggacca tcgcccactg aacagcccgg cggctccccg
    22861 ctcgaccacc gggctgctca atgctcaccc ggccagggcg tagcgaggca cctcccgctc
    22921 gtccccgggc acccaactgc cgtgcaggcc gagcgggaca cgtacgggca gatgaatacg
    22981 ggcgatcggc tcaccggtga agtccagggc cgacaacagc agatcggtgg cgccgcgctc
    23041 cggatcgaag accgccgtca gatcgaccgt ccatcggtcc agtgtggggc ggctggtgcc
    23101 gacgtccctg atgtcgaagc cctccgggtg ccggaccacg tcgatgacga cttcactgcc
    23161 gtcttcgtag gcgttgagcg tgtgccccac caggctcggc gcgacctcga accagcgcac
    23221 cgcacccccg gcccgcggca tcacgcccac ccgcgccggg cggttgccgt cccagacgaa
    23281 cgggatcccg gtgggcagat gagcggcgct gaacaccacg ggcgagtcga agaggagcac
    23341 atggcggtcg gtcagggcga agtcgtgcat ataggggttg cccggcacct cgacggtagt
    23401 ggcccgcagg accacgccgg tctcgtccat cacgatgtgc tgaacctggt cggagccgta
    23461 gcggaacgcc agcgaatgca gctcacgggt gcgggggtcg aagagggagt gggcgttggc
    23521 gctgtagccc tgcggtgtcg ccccgagagc gcaggggccg atcgtgtcca ggtcgtaggt
    23581 gagttcgtac gggcgtatcc cgccctcgat gagtgcgaag gtacggcccg cgaggccgac
    23641 gacccgcacg ttgggggaga tgtccatcag ttcgtcgacg ggcgtcccgc gccgtggctc
    23701 gccgagccgg tcggcgaccg cggtggagcg gacccagcgg ttgcggtacc actcggcgcg
    23761 gccgtcgcgg atccggacgc cgtggaccat gcccgcaccg agggtccaga gtgggtggcg
    23821 gcgtcctcga tgcccagtgg gttgggcccg ttgcgcaggt agcggccatt gagatgggcg
    23881 ggtaaccggc cggtgacggg caggtcgtag gcggtgatct cctcggtgac cggagcgaac
    23941 gccccccccc gagagatagc ggttgccggt catgaagtct ggccctcttc ggtgggggag
    24001 gcggagtcgg cggtggcggt ggcgggccgg gcgctgaagg cctgtgccac cgccgtcatc
    24061 agcgtttcgt agcggtgcgc ggcggtgtcc ggggggaagt gtccggcgat ctccaggctc
    24121 accgccccgt gtgacgcggc ccagaggatc ttcgccatct cctgggcgtc gcccggccgg
    24181 aaggccccgg agtcgatgca ggcggtcacg gcagcggtcg aggcctcaaa tgcggtctcg
    24241 gcgacggcct gctcgaacat cacgcggtag taggcgggtt cggccagggc gtgctcccgg
    24301 taggccgtcc cgaggttgct cagtcgcgtc aacgggtcag ccgcggcagg aacgcgctcc
    24361 tgcgcccggc gcagccgggc gaacccttcc cctgggtaac aacgtaccct gtgggaaaca
    24421 ttgttacccg agcgggtggc tgttacctct gcgtgctgat gctgcgccgt tcctgctcgc
    24481 cgttcctgtg cctgtgctgg tgttgcccgc ccacacccgg gggagtcgtc cgcacctggg
    24541 ggagtcgtcc ggagccgtcg atcccgcccc cggatcccgc cgtgtcagcc gtccttgttg
    24601 gccttgagtt tccgccacac cgcgctcagt gcctcaa
//
