LOCUS       NZ_CP029541            23502 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. NEAU-S7GS2 chromosome, complete genome.
ACCESSION   NZ_CP029541
VERSION     NZ_CP029541.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. NEAU-S7GS2
  ORGANISM  Streptomyces sp. NEAU-S7GS2
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9641634)
  AUTHORS   Zhang,J.
  TITLE     Streptomyces sp. NEAU-S7GS2 isolated from saline-alkaline soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9641634)
  AUTHORS   Zhang,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2018) School of Life Science, Northeast
            Agricultural University, Mucai Street, Harbin 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: AMRT Link v. v5.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003173275.1-RS_2024_05_07
            Annotation Date                   :: 05/07/2024 05:28:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,458
            CDSs (total)                      :: 8,365
            Genes (coding)                    :: 8,052
            CDSs (with protein)               :: 8,052
            Genes (RNA)                       :: 93
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 313
            CDSs (without protein)            :: 313
            Pseudo Genes (ambiguous residues) :: 0 of 313
            Pseudo Genes (frameshifted)       :: 144 of 313
            Pseudo Genes (incomplete)         :: 230 of 313
            Pseudo Genes (internal stop)      :: 21 of 313
            Pseudo Genes (multiple problems)  :: 74 of 313
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:52:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2015956
            Orig. end                         :: 2039458
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029541.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23502
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="blactam"
                     /region_number="14"
                     /rules="(BLS or CAS or tabtoxin)"
                     /tool="antismash"
     cand_cluster    1..23502
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(BLS or CAS or tabtoxin)"
                     /kind="single"
                     /product="blactam"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23502
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:13502](+)"
                     /cutoff="20000"
                     /detection_rule="(BLS or CAS or tabtoxin)"
                     /neighbourhood="10000"
                     /product="blactam"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13502
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(BLS or CAS or tabtoxin)"
                     /neighbourhood="10000"
                     /product="blactam"
                     /protocluster_number="1"
     misc_feature    complement(703..719)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.08"
                     /tool="antismash"
     misc_feature    complement(706..715)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            1103..4246
                     /locus_tag="DKG71_RS07970"
                     /old_locus_tag="DKG71_07970"
     CDS             1103..4246
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961118.1"
                     /locus_tag="DKG71_RS07970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_07970"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_109888287.1"
                     /transl_table=11
                     /translation="MKDDARFPGLRFDLLGPLSVRSSGKTVDLGAPRQRALLALLLIHV
                     GNVVSLPTIIKAIWGSSPPSQVTGTLQAYVSRLRKLLARHDRSIRLVHHLQGYLLEADA
                     RLVDAAVFEVKVRECRELIKAGDLDAARSTAGAALELWKGTPLGELYGYEFAVAEADRL
                     EHVRLRALEVWAQASLGLGAYEEVTVRLGEELRRNPGLERLGGQLMTAQYHSGQSAEAL
                     LTYERMRHAVAEDLGADLSRELQALHGKILRQELPAAPVPEPADRTTPAPALPTPAPPA
                     SASAPAPVPPEAEKPEPPDSPPPGDRLVGRQAEMKRLQQLLAGARGGQGHVVLVYGEQG
                     IGKTRLLQQAERCLATTEFRLARSYCVGTLPDPGYWTWEHIVRQLELTGGAGEAAAVDV
                     VAQADWLPEQHLTHQMRICQAVLAAAERTPVVLLLEDLHLAQAPVLEVLQLLVKQIGRA
                     RVLVLATLRDHELAKDPAVRRAVGRILQEGNSSMLRLEGLAEEQSRELIASASGAAPSP
                     GKAQQLQRASGGNPFLLLSAVCAQSAGERPSVPFEVREVLHERLSECSPDTLEVLTLCA
                     VMGMDVHRPLLADLLSTLGLPQTLIDDAVQTGLLRHDRAAEGRLSFAHGLTRDFLLDAT
                     QPVTRARWHHRVATILALRSRPGDDAAEIRRHCLAAARLLGARAGVRPLLTLADREQAR
                     FSHTAALHWLEAAASVVAALPGDEPTSAVELQLRKRMMWLQALMEGYGSARVEAILWHA
                     QKLERAFDGTQPTGLLHAQAMRAITAGQYPEAAEIGGLLYELADHGGGPEARSAACYVG
                     GVTQYVSGRLDESLTALAEGVGIIDTLLESPRVPLRPSALLRDQRIDYRAYLALGHCLN
                     GDRVQTRRYRSELLHLTQSDRYDRPWDRAFARYVDALIAVTEYDVRGAWLAGRAGLDLA
                     ARCQLPFWHRMLAIPLGWAEVHQGMHEQGLARMRKALQDAVRHRTVLRRTLHLGLLADA
                     LHRTGAHDEARSTSATAVKEIEERGEYFCYRPQWPFARLLQELGTGTAAAQHLDHEPR"
     misc_feature    1226..1228
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    3641..3643
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4352..4933)
                     /locus_tag="DKG71_RS07975"
                     /old_locus_tag="DKG71_07975"
     CDS             complement(4352..4933)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090796.1"
                     /locus_tag="DKG71_RS07975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_07975"
                     /product="flavin reductase family protein"
                     /protein_id="WP_093638844.1"
                     /transl_table=11
                     /translation="MSLSAADSSLQRGTPQSGQASVTAGLLRRVAGHYPTGVVLVTGPR
                     PAPGQPPPAMVVGTFTSVSLHPALVGFLPAKSSTTWPRIRAAGRFCVNVLGADQQQVCR
                     RFAAADPHRWEVPHRETATGSPLLLDALAWFDCEVAGEAEAGDHWFVTGTVRDLGTGRP
                     GPPLVFLRGGYGHCAEDTDAARSGRPAGPD"
     gene            complement(4999..6198)
                     /locus_tag="DKG71_RS07980"
                     /old_locus_tag="DKG71_07980"
     CDS             complement(4999..6198)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090797.1"
                     /locus_tag="DKG71_RS07980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_07980"
                     /product="serine hydroxymethyltransferase"
                     /protein_id="WP_109888289.1"
                     /transl_table=11
                     /translation="MDVLAALQRRPSLNLFPIENRLSPRAAAALATDAVNRYPYSETPV
                     AVYGDVTGLKDVYDYCVDLTKEFYGARHAFVPFLSGLHTMHTVLTAVAPPGGRVMVLAP
                     DDGGHYATVTICEGFGYEVDYLPFDRQRLEIDHAALAARTAERPVDVIYLDASTALRFP
                     DARALRAAAPGAILCLDASHLLGLLPAAPQTLVLDGGFDSISGSTHKTLPGPQKGLLVT
                     NSDSLAEKMAARIPFTASSSHSATVGSLAITLEELMPHRVEYAQQIIANARRLAGELAG
                     LGFDVAGEEFGHTDTHQVWVHPPEGNTPHEWGRLLTRTDIRTTTVVLPSSRSSGLRLGT
                     QELTRWGMKENDMARVAELLARLLLHHEDSGKVAADVADLARAFPGVAYAGGSAAVTAG
                     "
     gene            complement(6245..6700)
                     /locus_tag="DKG71_RS07985"
                     /old_locus_tag="DKG71_07985"
     CDS             complement(6245..6700)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961116.1"
                     /locus_tag="DKG71_RS07985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_07985"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_018090798.1"
                     /transl_table=11
                     /translation="MTVAPAGMTDEQRKAVITAYLHAFDNGGVGSDGTAVLDFFAEDAT
                     FFFPKWGLARGKATIARMFTDLGGTIQAATHHLWSVNWITTGTDLLAVEGTTHGEHRDG
                     PWRAGVPEWGAGRWCGVFEVRDSLIQRAFIYLDPDYAGKDTARYPWL"
     misc_feature    6810..6830
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.0"
                     /tool="antismash"
     gene            complement(6854..7849)
                     /locus_tag="DKG71_RS07990"
                     /old_locus_tag="DKG71_07990"
     CDS             complement(6854..7849)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090799.1"
                     /locus_tag="DKG71_RS07990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_07990"
                     /product="aldo/keto reductase"
                     /protein_id="WP_093638850.1"
                     /transl_table=11
                     /translation="MPASPRPLVRTLRELHVSAQGLGCLPTTAFYGRPDPARAVATIRA
                     ALDAGVTLLDTADVQGLGAGEELLGRAVAGRRDEVVIASKFGMVRSADGAFQGLCGEPS
                     YVRTACERSLRRLGVDHLDLYYQHWTDPAVPVEETAGAVAELVRAGKVRHFGLSEPSVA
                     TLRRADAVHPVTAVQSEWSLWSRDIEAEVVPACRALGIGIVAYAPLGRGFLTGGIRTTD
                     DLAAEDFRRGQPRFSADGLAHNRALLDRLRPLAAARGLTLAQLALAWLHHHGPDVVPIP
                     GTSDPAHLTENLAAAAVRLDEDDLAAVAEALAVPVLGERYAPALLAMTGN"
     misc_feature    complement(7979..7993)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     gene            8284..9999
                     /locus_tag="DKG71_RS07995"
                     /old_locus_tag="DKG71_07995"
     CDS             8284..9999
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090800.1"
                     /locus_tag="DKG71_RS07995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_07995"
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="WP_018090800.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.7e-43, bitscore:
                     146.5, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-31, bitscore:
                     107.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRVSTTPGTNPTTAHALLQRLRDHGVQTVFGVVGREAASILFDE
                     VEGIDFVLTRHEFTAGVAADVLARISGRPQACWATLGPGMTNLSTGVATSILDRSPVIA
                     LAAQSESYDIFPNDTHQCLDSVAVMRPMTKYAVELQRPDDITDLVDSAVAAATTEPVGP
                     SFLSLPVDLLAGEVDTTQERPAVRAPGKPVGAVQDGWQAEAERSAELLAAAEHPVLVVG
                     AAAIRSGAVPAIRALAERLNIPVITTYIAKGVLPHGHRLNYGAVTGYMDGILSFPALET
                     LFGPADLILTLGYDYAEDLRPSMWQRGGAKQTVRVSPTVNPVPRVYRPDVDVVTDVLAF
                     VEHLEAHTGQVAAKTPHDIAPLRERIAEFLSDPERHADGMRVHQVMDCMNTVMAESAEP
                     GEGTIVSDIGFFRHYGVLFARADQPFGFLTSAGCSSFGYGIPAAMGAQLARPGQPTFLI
                     AGDGGFHSNSSDLETIARLNLPIVTVVVNNDTNGLIELYQNIGHHRSHDPAVKFTGVDF
                     TELAKANGVEAVRAGSREELLAALRKGAGLGRPFLIEVPVNYDFQAGGFAALSI"
     gene            10001..11527
                     /locus_tag="DKG71_RS08000"
                     /old_locus_tag="DKG71_08000"
     CDS             10001..11527
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     blactam: BLS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090801.1"
                     /locus_tag="DKG71_RS08000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_08000"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_109888291.1"
                     /sec_met_domain="GATase_7 (E-value: 2e-11, bitscore: 42.8,
                     seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="BLS (E-value: 3.4e-154, bitscore: 512.5,
                     seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 4.3e-27, bitscore:
                     94.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERTLPAATGFLAAVHQDGGRAPAPVFASLGSCALEREERHGHTL
                     HTGLLHTGAPEAARAYGPRCAVVFAGELYNQAELRSLLPPGAGPDGDAQLVRALFDIYD
                     LHAFRLLNGRFAALVQGEGRVLLATDHAGSVPLYLTAAPGRVLAATEAKALRTAPTGRP
                     LPAARPVRRLPGVHQVPAGTVLEVALGTGGCTAHRTWAPPLSRRILPEDEAVAAVRRAL
                     EDAVQVRMGPEAPLVVLSGGIDSSSVAALAAGRAAGPVDTVSMGTDEADEFPQARVVAA
                     HLQTAHRELTIPTDDLLRRLPHTVWAAESLDPDIIEYLLPLTALYLRLGDTGRRILTGY
                     GADIPLGGMHREDRLPALDTALAHDMETFDGLNEMSPVLSGIGGHWSTHPYWDREVLDV
                     LVPLEAGLKRRYGQDKWVLRAAMGDVLPQETVLRPKLGVHEGSGTTSSFSRLLTAAGVP
                     EGRVHHAKRLVVQELFDQVVVAGRHPDEVATEEVVQLAAGQLESRTQPIS"
     gene            11569..12513
                     /gene="speB"
                     /locus_tag="DKG71_RS08005"
                     /old_locus_tag="DKG71_08005"
     CDS             11569..12513
                     /EC_number="3.5.3.11"
                     /GO_function="GO:0008783 - agmatinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="speB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152697.1"
                     /locus_tag="DKG71_RS08005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_08005"
                     /product="agmatinase"
                     /protein_id="WP_018090802.1"
                     /transl_table=11
                     /translation="MERIDTTVSPRYAQIPTFMRLPHDPAPRGRDVVVIGAPYDGGTSY
                     RPGARFGPRAIRSESGLIHGVGIDRGPGTFDLISCVDAGDIDLTPFNMHIAMDTAQRRL
                     AELLADNAAFLMLGGDHSLTLAALRAVSAKHGPLAVLHLDAHSDTNPAFYGGEYHHGTP
                     FRHAIEEKLVDPQRMVQIGIRGHNPQPDSLDYARGHGVHIVTADTFADLGNDAATRLVR
                     DIVGDAPLYVSVDIDVVDPAFAPGTGTPAPGGPSSREVLALLRGIGDLRPVGFDVMEVS
                     PLYDHGGITSVLATEIGAELLYQYARAHVQEHA"
     gene            12528..13502
                     /gene="cs1"
                     /locus_tag="DKG71_RS08010"
                     /old_locus_tag="DKG71_08010"
     CDS             12528..13502
                     /EC_number="1.14.11.21"
                     /GO_function="GO:0033758 - clavaminate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0033050 - clavulanic acid biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (114-299). E-value: 4.6e-18. Score:
                     57.9. Matches aSDomain:
                     nrpspksdomains_DKG71_RS08010_TauD.1"
                     /codon_start=1
                     /gene="cs1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     blactam: CAS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961114.1"
                     /locus_tag="DKG71_RS08010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_08010"
                     /product="clavaminate synthase Cs1"
                     /protein_id="WP_026169831.1"
                     /sec_met_domain="CAS (E-value: 9.3e-185, bitscore: 612.4,
                     seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="TauD (E-value: 6.3e-16, bitscore: 57.9,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVVDCTAFAGELRALAARLPQTPRADLDAFLESAQTAATALPGA
                     LATALDTFNAEGNQDGYLMLRGLPVEDEAALPPTPTSTPAPTDRPLLTMEAMLGVVGRR
                     LGLHTGYKELRAGTVYHDVYPSPDAHYLSSETSETLLEFHTEMAYHVLQPNYVMLACTR
                     ADHERTAATLVASVRKALPLLSDGVRERLFGRKMPCCVDVSFRGGVPDPGAIAQVTPLY
                     GDPEDPFIGYDRELLTPDVPEDVAAVAALSKALDEVTEAVYLTPGDVLIVDNFRTTHAR
                     TPFSPRWDGRDRWLHRVYIRTPRNGQLSGGERAGDVVAFTPRG"
     aSDomain        12870..13424
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DKG71_RS08010_TauD.1"
                     /evalue="4.60E-18"
                     /label="DKG71_RS08010_TauD.1"
                     /locus_tag="DKG71_RS08010"
                     /protein_end="299"
                     /protein_start="114"
                     /score="57.9"
                     /tool="antismash"
                     /translation="RAGTVYHDVYPSPDAHYLSSETSETLLEFHTEMAYHVLQPNYVML
                     ACTRADHERTAATLVASVRKALPLLSDGVRERLFGRKMPCCVDVSFRGGVPDPGAIAQV
                     TPLYGDPEDPFIGYDRELLTPDVPEDVAAVAALSKALDEVTEAVYLTPGDVLIVDNFRT
                     THARTPFSPRWDGRDRWLHRVY"
     gene            13661..14842
                     /gene="argJ"
                     /locus_tag="DKG71_RS08015"
                     /old_locus_tag="DKG71_08015"
     CDS             13661..14842
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /GO_function="GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argJ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1220: bifunctional ornithine"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952513.1"
                     /locus_tag="DKG71_RS08015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_08015"
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="WP_109888294.1"
                     /transl_table=11
                     /translation="MTDSNTYEPRGFAVHTAPVGLGDDGRDDFTVLLSTAPATVSAVFT
                     RSRFAGPSVVLSRAAAADHRARGVVVLARNANVATGAEGERNAREVRAAVAQAAGLPEE
                     ELLIASTGVIGRQYPMPALRDHLKTLTVPLPEGGFDRAARAIMTTDTRPKQACRRVGDA
                     VVAGIAKGVGMMEPDMATLLTFFATDARLDPAEQDRIFRRVMDRTFNAVSIDTDTSTSD
                     TAALFANGLAGEVDPAAFEEALYEVALTLVKDIARDGEGAGKLIEVRVRGARDDAQAKR
                     VAKAVVNSPLVKTAVHGGDPNWGRVAMAIGKCSDDTDIEQDRVVIRFGEVAVYPPGLPG
                     ARSEDEVRDAVAAELAGSEVVIGIDLGIADGAFTVYGCDLTEGYIRLNADYST"
     gene            complement(14914..15918)
                     /locus_tag="DKG71_RS08020"
                     /old_locus_tag="DKG71_08020"
     CDS             complement(14914..15918)
                     /NRPS_PKS="Domain: Abhydrolase_1 (39-162). E-value:
                     1.1e-11. Score: 36.8. Matches aSDomain:
                     nrpspksdomains_DKG71_RS08020_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090805.1"
                     /locus_tag="DKG71_RS08020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_08020"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_109888296.1"
                     /sec_met_domain="PF00561 (E-value: 7.9e-11, bitscore: 41.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHRIFELDALPLLSGETLTDARIGYAVHGTLDADGANAVLCPSF
                     FGGDHTGYDWLIGEGRPLDTRRYCVITAGLFGNGVSSSPSNHPSGAGFPLITPQDNVAA
                     QHRLLTEHLGVRELALVTGWSMGAAHTYQWAVSHPRMVRRIAPVCGAPVTSEHNQVFLA
                     GLAAALTADGGAERGRRAAGRLFAGWGTSHPFWARQTYRELGFATREDYLTGFWEEFFV
                     AGPATADLLAMVRTWESTDVGATPGSGGSAEAALASVTAEAAVLPGALDQCFAAADEER
                     VARTLPHAVLEVIPGVWGHLAGAGADAADREFVGTALRRLLARRPATVPACDG"
     aSDomain        complement(15433..15801)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DKG71_RS08020_Abhydrolase_1.1"
                     /evalue="1.10E-11"
                     /label="DKG71_RS08020_Abhydrolase_1.1"
                     /locus_tag="DKG71_RS08020"
                     /protein_end="162"
                     /protein_start="39"
                     /score="36.8"
                     /tool="antismash"
                     /translation="VLCPSFFGGDHTGYDWLIGEGRPLDTRRYCVITAGLFGNGVSSSP
                     SNHPSGAGFPLITPQDNVAAQHRLLTEHLGVRELALVTGWSMGAAHTYQWAVSHPRMVR
                     RIAPVCGAPVTSEHNQVFL"
     gene            complement(16026..17210)
                     /locus_tag="DKG71_RS08025"
                     /old_locus_tag="DKG71_08025"
     CDS             complement(16026..17210)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961112.1"
                     /locus_tag="DKG71_RS08025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_08025"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_018090806.1"
                     /transl_table=11
                     /translation="MKSILFYLPTVGSHAQILRGMSGVNPQNYQNMLWQLTRQAQAADE
                     LGYWGLSFTEHHFHVEGFEVSNNPVMLGLYLGMQTKHIRVGQMANILPFHNPLRLAEDL
                     AMLDHMTRGRTFVGIARGFQKRWAEVMGQVYGVGGTLSDAGESDRRNRALFEEHWEILK
                     KAWTTETFSHSGERWTIPVKDLEFPYEAVRRYGRGLDDDGVVQEVGIAPKPYQRPHPPV
                     FQPFSFSEDTFRFCAREGVVPILMNTDDRVVRRLMDLYQEEAEAAGHGTLRRGERVGVM
                     KDVLVSRDADEAHHWAARGGGFIFENWFGPMGFTEALRNEGETGPIGSDYGTLVERGLE
                     WVGTPDDINRKIEKLVAHHDPEYLLQCQYSGLIPHDVQMRSLELWATEIAPNWL"
     gene            17437..18801
                     /locus_tag="DKG71_RS08030"
                     /old_locus_tag="DKG71_08030"
     CDS             17437..18801
                     /NRPS_PKS="Domain: Aminotran_3 (40-385). E-value: 1.3e-87.
                     Score: 285.9. Matches aSDomain:
                     nrpspksdomains_DKG71_RS08030_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090807.1"
                     /locus_tag="DKG71_RS08030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_08030"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_093638857.1"
                     /sec_met_domain="Aminotran_3 (E-value: 6.1e-83, bitscore:
                     277.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSDRPAPSGASGAELAATDRATLIHPTLPAHRTDRTVLVSGSGS
                     RVRDAHGREYLDASAVLGVSQVGHGRQELAQAAAEQMTRLDYFHTWGPLSNDRAVELAA
                     RLAGLSPEPLRRVYFTSGGAEGNEIALRMARLYHHRRGEPQRTWILSRRMAYHGIGYGS
                     GGVSGFPVYHDGFGPSLPDVHFLTPPHPYRRELFSGAEVTDFCLAELRETIERTGPERI
                     AAMIGEPVMGGGGAVIPPADYWPRVAELLRSYGILLISDEVVTAYGRLGHWFAAEHFGA
                     VPDIMVTAKGLTSGYVPHGAVLTTDEVAAEVTGDHGFPVGYTYTGHPTACAVALANLDI
                     IEREKLMANATVVGDHLGWRLAELTDLPVVGEVRQLGLMLAVELVSDKDSRRPLTGGTL
                     AVADALREQAGILLRTNPNALVINPPLVFSRADADELVDGLRSVLSRTGPDGQVH"
     aSDomain        17557..18591
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DKG71_RS08030_Aminotran_3.1"
                     /evalue="1.30E-87"
                     /label="DKG71_RS08030_Aminotran_3.1"
                     /locus_tag="DKG71_RS08030"
                     /protein_end="385"
                     /protein_start="40"
                     /score="285.9"
                     /tool="antismash"
                     /translation="SGSGSRVRDAHGREYLDASAVLGVSQVGHGRQELAQAAAEQMTRL
                     DYFHTWGPLSNDRAVELAARLAGLSPEPLRRVYFTSGGAEGNEIALRMARLYHHRRGEP
                     QRTWILSRRMAYHGIGYGSGGVSGFPVYHDGFGPSLPDVHFLTPPHPYRRELFSGAEVT
                     DFCLAELRETIERTGPERIAAMIGEPVMGGGGAVIPPADYWPRVAELLRSYGILLISDE
                     VVTAYGRLGHWFAAEHFGAVPDIMVTAKGLTSGYVPHGAVLTTDEVAAEVTGDHGFPVG
                     YTYTGHPTACAVALANLDIIEREKLMANATVVGDHLGWRLAELTDLPVVGEVRQLGLML
                     AVELV"
     gene            19006..20274
                     /locus_tag="DKG71_RS08035"
                     /old_locus_tag="DKG71_08035"
     CDS             19006..20274
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090808.1"
                     /locus_tag="DKG71_RS08035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_08035"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_109888299.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 3.6e-06,
                     bitscore: 25.5, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQRPKIVLVGQLSSFPWVFDSAERAGIDLVLVPRGDDSVESAGR
                     AKSVVEVLPLDIDGDPESALSTLVERFRRDPFDGIMPGNEKVVPFVARAARMLGLPGLP
                     EEVAAVVRDKRSMRRLLREAGLGAPGFVSLDGPDRWADALTLRFPVVVKPANGYSSLGV
                     VRVDDKDQLVPAVARTWELCETELRQAGGPADGVGVLVEEYLDGPEVAAESLVHQGRVR
                     VCAIEWKGEMTGPYFEETTVRAPAQLPADVLAAIEAEVIGAHHAFGVTEGATHTELRLI
                     GGVRPVLLEMAARIGGAGVNHYLTHIAGGIDLAAEALRIHLGQEPVCWSQEPVPTGHAA
                     AYSVPVGKGGRIVRVHGLDAVRADPRVDQVVQTVGPGALLRPYPDWAGYPAIVLSHHES
                     DAAAVEFRDHLVRTLHVEYEEES"
     gene            20298..21485
                     /locus_tag="DKG71_RS08040"
                     /old_locus_tag="DKG71_08040"
     CDS             20298..21485
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="DKG71_RS08040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_08040"
                     /product="MFS transporter"
                     /protein_id="WP_162596866.1"
                     /transl_table=11
                     /translation="MVKALRTSLGGLPRPFWWLWGETLITSAGGFVLPFLAIYLTSVRG
                     YSVSFASLALTVFGVGSGIASLAGGVLADRLGRRVVLLASEVLAVVGMLALGTARTQIM
                     VLVGTLVVGVGLNATRPARAAAVADLVSEEGRPRAFSLLYWGTNLGSSVAAVSAGLAAE
                     HGFFLLFVVNACANLAAGAVVYRCVPETRPEPVPRRGSKSLPAGAVHRDRPFLVLLGSV
                     LLLGILFQQPLVALPLTMTADGLSPAGYGLAMMMNGLVIVIFQIPLTRLAGRIRPEFAL
                     AAATVLTGIGLGCTAAVHSVPGYAATVVLWSLGEIVIWPTCMTLVAALAPPHQQGAYQG
                     WFLSVWSVSVALAPLFSSQLIGAFGGTAVVWTACLVLALVAATGHLVLARLRRPV"
     gene            complement(21603..22409)
                     /locus_tag="DKG71_RS08045"
                     /old_locus_tag="DKG71_08045"
     CDS             complement(21603..22409)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012318.4"
                     /locus_tag="DKG71_RS08045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_08045"
                     /product="serine protease"
                     /protein_id="WP_161299330.1"
                     /transl_table=11
                     /translation="MARHGYLRWPVLAGLMVLVGAGFAVLPAHPAQAVIGGQKSSTAAA
                     PWTVTINLWRQTDTYPRSGQFCGGTLVTPRKVVTAAHCVVDEAPTDLGVVAGRTDLRRH
                     DGRMRKVTKAWIHPRFGRHLENDVAVLTLDKPMPPQYTPLPVATAADTGPYRPGTRARV
                     HGWGLLDNEGREANVLRSANLRVLADRTCQRLNPWGDIDPKMHVCANDPVTGAHHAEGD
                     SGGPLVAGGKLIGIVSWLAGGNATTPTTGVYTRVAAFSREIGRQLG"
     gene            complement(22430..23230)
                     /locus_tag="DKG71_RS08050"
                     /old_locus_tag="DKG71_08050"
     CDS             complement(22430..23230)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012318.4"
                     /locus_tag="DKG71_RS08050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_08050"
                     /product="serine protease"
                     /protein_id="WP_159489586.1"
                     /transl_table=11
                     /translation="MSKARTRRGTLAGAVLVGAALVGSSAPPAAAVVGGDRAEIKKYPW
                     TVALTSRDVKDPDCAGTLVAPRKVLTASHCVSPATVDGVRVVGGREDLRDTRKGTVRKV
                     AKLWIHPKADTEGNGATYAHDLAVLTLNAPMPYRTLPLATPAQQKLYEEGTPNRVLGWG
                     STTGRDDDLRVPPLQTALIPNRGDEQCITAYGTRRYQKSYTMCLGYPAGGVSACSGDSG
                     GPVVVRGRLVGVISGGGSCTSRLYPGVAVKAASYYPLLQSRIAG"
     misc_feature    23433..23447
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 21.93"
                     /tool="antismash"
     misc_feature    complement(23452..23470)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.52"
                     /tool="antismash"
ORIGIN
        1 accgagagcg gcgccgcctc cagcggcgcc accgcgaacg gcaagcccgg cggaaccggc
       61 aagacgcaag gagagggttc cggcaacgga cagggcgcct ccggcggtca gggcaggagc
      121 gccggaaagg gcggaggcac cgcggacggc tcggcggcca cctgtacggg agcgaacacc
      181 aaggccgtca tcaccaaggt cacacgcccc atcaatcacc tgctcctcac gatcaccaac
      241 acggggtcgc gctcctgcga cgcctactcg gcgccccttc tgcgcttcga cgacgagcag
      301 tcggcgaccc ggatcatgga ggacagcaag ccgcaggccg tcgtgaccct cgccccgggc
      361 cggtccgcct atgcctcgat cctgctcagc ggcgagggcg gcgatgactc cggtggccgc
      421 accgcccagc gcctcgaggt gcacttcgct ccgcggagcg gttccggttc gacgggcacc
      481 cccctcaagc tcaccctgcc cgcgggtacg cacaaggaca acgacgccgc cgtcacctac
      541 tggcaggact cggcgtccga cgcgctgcag cactgatccc gacccggtcc cggtcagccc
      601 tctcccgtcc ggaaccaccc ggcccgccgc ccgcgcccgg gcgggcggag gggcggccgt
      661 ggcaaggccc cttacccata tcggaggcac ctatagcagc tccactcaga aaacaacaat
      721 tccgttggag aatgaaccaa aattcgcgcg gaagtcatca tttacagcat gaagagctat
      781 agccgtcgcc ctgcccgccg tctgcgggga cctgacgcct cccgtggagc gctgagcgca
      841 gcccctgcgg cacggggagc tgccgggccg cacggcctcg ccccgtcgac cggcaccacg
      901 cggtccgcac acgacgccgg ctcttccttc gcacgccctc cggaacggct ccgggcgggt
      961 actccctctg ttcccgcccg gggtcccgga cccggaacgc gctgagacct cggaacgctc
     1021 aggttgcgtc caagatctga ggtctcgtca gcttccgttt acgttcatgt tcttccgtca
     1081 ttctctccag tcgggatgca cgatgaaaga tgatgcacgt ttccctgggc ttcggttcga
     1141 cctccttggc cccttgagtg tgagatccag tgggaagacg gtcgacctcg gtgcaccaag
     1201 acagcgggcc ctgctcgccc tgctgttaat ccacgtgggc aatgtggtgt cgctgcccac
     1261 gatcatcaag gcgatctggg ggtccagccc accgagtcag gtcacgggga ccctgcaggc
     1321 gtacgtgtcc cggctgcgca agctgctggc ccgccacgac cgctcgatcc ggctcgtcca
     1381 ccacctccag ggatatctgc tcgaagccga tgcgcggctg gtcgatgccg cggtcttcga
     1441 ggtgaaggtc agggagtgcc gggaactgat caaggccggc gatctcgacg ccgcacgctc
     1501 gacggcgggg gccgccctgg agctgtggaa gggcactcct ttgggcgagt tgtacggcta
     1561 cgagttcgcg gtggcggaag cggaccgcct ggaacatgtc cgcctccggg cacttgaggt
     1621 gtgggcccag gcgtccctcg gtctgggcgc ctacgaggag gtgacggtcc ggctcggtga
     1681 ggaactccgc cgcaatcccg gactggagcg gctgggcggg cagttgatga cggcccagta
     1741 ccactccggc cagtcggcgg aggcgctgct gacctatgag cggatgcgcc atgcggtggc
     1801 ggaggacctg ggggccgacc tcagccggga actgcaggcg ctgcacggga agatcctgcg
     1861 gcaggagctt ccggccgcac cggtccccga gccggcggac cggaccacgc ccgcgccggc
     1921 actccccacg ccggcacccc ccgcttcggc atccgccccg gcacccgtgc cgccggaagc
     1981 ggagaagccg gagccacccg actccccgcc gccgggtgac cggctcgtcg gccgtcaggc
     2041 ggagatgaag cggctgcagc agctgctggc cggcgcgcgc ggcggtcagg gccatgtggt
     2101 gctggtctac ggcgagcagg gcataggcaa gacgcggctg ctgcagcagg ctgagcgctg
     2161 tcttgccacc accgagttcc ggttggcgcg ctcgtactgc gtcgggaccc tgccggatcc
     2221 cggctactgg acgtgggaac acatcgtgcg gcagctggag ttgacgggcg gggccggtga
     2281 ggccgccgcc gtggacgtcg tcgcgcaggc cgactggctg cccgagcagc acctcaccca
     2341 ccagatgcgg atctgccagg ccgtgctcgc cgccgcggaa cggacacccg tggtcctgct
     2401 tctggaggac ctgcacctcg cccaggcccc cgtactggaa gtgctccagc tgctggtcaa
     2461 acagatcggc cgggcccggg tcctggtgct ggccaccctc cgcgaccacg agctggcgaa
     2521 ggacccggcg gtgcgccgcg ccgtgggccg tatcctccag gaaggcaaca gcagcatgct
     2581 ccggctggag ggactcgccg aggagcagag ccgggaactg atcgcctcgg cctccggcgc
     2641 ggcgccctcg cccggcaagg cccagcagct ccagcgcgcc tccggcggca accccttcct
     2701 cctgctcagc gcggtctgcg cacagtccgc cggggagcgg ccctcggtcc cgttcgaggt
     2761 gcgcgaggtg ctccacgagc ggctgagcga atgctccccg gacacgctcg aagtgctcac
     2821 cctctgcgcc gtgatgggca tggacgtgca ccgccccctg ctcgcggacc tgctgtccac
     2881 cctcgggctg ccgcagaccc tgatcgacga cgcggtgcag accggcctgc tgcgccacga
     2941 ccgggccgcg gagggccggc tctccttcgc ccatggtctg acgcgtgact tcctgctgga
     3001 cgccacccag ccggtcaccc gcgcccggtg gcaccatcgg gtggccacca tcctggcgct
     3061 gcggagccgg ccgggtgacg acgccgcgga gatccgccgc cactgcctgg cggccgcccg
     3121 gctcctgggt gcccgcgcgg gcgtgcgccc gctgctgacc ctggccgacc gggagcaggc
     3181 ccgcttctcc catacggccg cactgcactg gctggaggcc gcggcgtcgg tcgtcgcggc
     3241 gctgcccggg gacgagccga cctctgccgt ggaactgcag ctgcgcaagc ggatgatgtg
     3301 gctgcaggcc ctgatggaag gctacggctc ggcccgggtc gaggcgatcc tctggcacgc
     3361 ccagaagctg gagcgggcct tcgacggcac ccagcccacc gggctgctgc acgcacaggc
     3421 gatgcgcgcg atcaccgcgg gccagtaccc ggaggcggcc gagatcggcg gcctgctcta
     3481 cgagctggcc gaccacggcg gcggtccgga ggcccggtcg gcggcctgtt acgtgggcgg
     3541 ggtcacccag tatgtgagcg gccggctgga cgagtcgctc accgcgctcg ccgagggcgt
     3601 cgggatcatc gacaccctgc tggaatcccc ccgcgtgccg ttacgcccga gcgcgctgct
     3661 gagggaccag cgcatcgact accgggccta cctggcgctc ggtcactgcc tcaacggcga
     3721 ccgggtccag acccggcgct accggtcgga gcttctgcac ctcacccagt ccgaccgcta
     3781 cgaccggccg tgggaccggg ccttcgcccg ttacgtcgac gccctcatcg ccgtgaccga
     3841 gtacgacgta cggggtgcct ggctggccgg gcgggcgggc ctggacctcg ccgcccgctg
     3901 ccaactcccg ttctggcacc gcatgctcgc catcccgctc ggctgggccg aggtgcacca
     3961 ggggatgcac gagcagggac tggcccggat gcggaaggcg ctgcaggacg cggtccggca
     4021 ccggaccgta ctgcgccgca ccctgcacct cgggctgctc gccgacgccc tgcaccgtac
     4081 gggtgcccac gacgaggccc ggagtacgag cgccaccgcc gtcaaggaga tcgaggagcg
     4141 cggcgagtac ttctgttacc ggccgcagtg gccgttcgcc cggcttctcc aggaactcgg
     4201 caccggcacc gcggccgcac agcacctcga tcacgaacct cgttgacggc agccggccgg
     4261 agccggaccg gacctcctcc gccgcgccgc ctgacgggcc gtgccgcggg cagcagtacg
     4321 gcgtgccgcg ggcagcgagc ggcggcggag gtcagtccgg gccggcgggc cgtccggacc
     4381 gggcggcgtc ggtgtcctcg gcgcagtggc cgtagccgcc gcgcagaaag accaggggcg
     4441 gaccgggccg cccggtgccg aggtcacgga ccgtcccggt gacgaaccag tggtcccccg
     4501 cctccgcctc gcccgccacc tcgcagtcga accaggcgag cgcgtcgagc aggagcgggg
     4561 aaccggtggc ggtttcccgg tggggcacct cccagcggtg ggggtcggcg gcggcgaagc
     4621 ggcggcagac ctgctgctgg tccgcaccga gcacattgac gcagaagcgg cccgccgccc
     4681 ggatccgcgg ccaggtggtc gaggacttcg cgggaaggaa gcccaccagc gccgggtgca
     4741 gcgacaccga ggtgaaggtg cccaccacca tggcgggtgg cggctgcccg ggtgccggtc
     4801 gcggcccggt gacgaggacc acccccgtgg ggtaatggcc ggccacccgg cgcagcagcc
     4861 cggccgtcac ggacgcctgg ccgctctgcg gggtaccgcg ctgcagcgaa ctgtccgccg
     4921 cggaaaggga catacgggtc tccttcgctc ctgccgggga cggccgcggg ccgggccgcg
     4981 gcacctcccc gtcccggctc agccggccgt caccgcggcg gaacccccgg cgtacgccac
     5041 gccggggaag gcccgggcca ggtcggcgac gtccgcggcg accttgccgg agtcctcgtg
     5101 gtgcagcagc agccgggcca gcagttcggc cacccgcgcc atgtcgttct ccttcatgcc
     5161 ccagcgggtc agttcctggg tgccgaggcg cagaccggaa ctccggctgc tgggcagcac
     5221 caccgtcgtg gtgcggatgt cggtgcgggt gagcagccgg ccccactcgt gcggggtgtt
     5281 gccctcgggc gggtgcaccc agacctggtg ggtgtcggtg tggccgaact cctcgccggc
     5341 cacgtcgaag ccgagcccgg ccagctcacc ggccagccgg cgggcgttgg cgatgatctg
     5401 ctgtgcgtac tccacccggt gcggcatcag ctcctccagg gtgatcgcca ggctgccgac
     5461 cgtcgccgag tgggagctgg acgccgtgaa ggggatccgt gcggccatct tctccgcgag
     5521 ggagtcgctg ttggtgacca gcagtccctt ctgcgggccg ggcagcgtct tgtgcgtact
     5581 gccggagatg ctgtcgaagc cgccgtcgag gaccagggtc tggggggccg cgggcagcag
     5641 gccgagcagg tgtgaggcgt ccaggcagag gatcgccccc ggagcagcgg cccgcagcgc
     5701 ccgggcatcg gggaagcgca gcgccgtgga ggcgtccagg tagatgacgt cgaccgggcg
     5761 ctccgccgtc cgcgccgcca gcgcggcatg gtcgatctcc aggcgctgcc ggtcgaaggg
     5821 gaggtagtcc acctcgtagc cgaagccctc gcagatggtg accgtggcgt agtggccgcc
     5881 gtcgtcgggg gccagcacca tcacccggcc gccgggcggg gccaccgcgg tgagcacggt
     5941 gtgcatggtg tgcagcccgg agaggaacgg tacgaaggcg tgccgggcgc cgtagaactc
     6001 cttggtgagg tccacgcagt agtcgtagac gtccttgagg ccggtgacgt cgccgtagac
     6061 cgccaccggc gtctccgagt acggatagcg gttgaccgcg tcggtggcga gggcggcggc
     6121 ggcccgtggc gagagccggt tctcgatcgg gaagaggttg aggctgggcc tgcgctgcaa
     6181 ggcggccagg acgtccatca gtgctccttg gcaggggggt ctgcgggggt ccgggggtgc
     6241 gacgtcacag ccacgggtag cgggcggtgt ccttgcccgc gtagtcgggg tccaggtaga
     6301 tgaaggcgcg ctggatgagg gagtcgcgca cctcgaagac tccgcaccag cgtccggcgc
     6361 cccactcggg cactcccgcc cgccagggcc cgtcgcggtg ctcgccgtgt gtggtgccct
     6421 cgaccgcgag caggtccgtc ccggtggtga tccagttgac ggaccacagg tggtgcgtgg
     6481 ccgcctggat ggtgcctccg aggtcggtga acatccgggc gatggtggcc tttccgcggg
     6541 ccagccccca tttcgggaag aagaaggtgg cgtcctcggc gaagaagtcg agcacggcgg
     6601 tcccgtcgct gccgaccccg ccgttgtcga aggcgtggag atatgcggtg atgacggcct
     6661 tgcgctgctc gtccgtcatg ccggccggtg ccacggtcat gaacgacctc cagatgtgcc
     6721 gggattctgc ggaagggggc gccacacgcg gagagcggcg gcgccattgc ggccgtccgg
     6781 cgggcggtct tcaccgtcgc agggcggcct tggcgtcggc ttgacgtctc gctgcggccc
     6841 ggcttgcaag gcgtcagttg ccggtcatgg cgagcagcgc gggcgcatag cgctccccca
     6901 gcaccgggac ggcgagcgcc tccgccaccg ccgccaggtc gtcctcgtcc agccggaccg
     6961 cggccgcggc gaggttctcg gtcagatggg ccgggtcgct ggtgccgggg atggggacga
     7021 cgtcggggcc gtggtggtgg agccaggcga gggcgagctg ggccagggtc aggccgcgtg
     7081 ccgcggcgag ggggcgcagt cggtccagca gcgcccggtt gtgcgccagg ccgtcggcgc
     7141 tgaacctcgg ctggccgcgg cggaagtcct cggcggccag gtcgtcggtg gtgcggatgc
     7201 ctccggtgag gaagccgcgg cccagcgggg cgtacgcgac gatgccgatg cccagcgcgc
     7261 ggcaggccgg caccacctcg gcctcgatgt cccgcgacca caggctccac tcgctctgca
     7321 ccgcggtcac cggatgcacc gcgtccgccc ggcgcagcgt ggccacggag ggctcggaga
     7381 gcccgaagtg gcggaccttg cccgcgcgga ccagctcggc caccgcgccc gcggtctcct
     7441 ccaccgggac cgccggatcg gtccagtgct ggtagtagag gtcgaggtgg tccacgccga
     7501 ggcggcgcag ggagcgctcg caggccgtgc gcacgtagga cggctcaccg cacagcccct
     7561 ggaacgcgcc gtcggcggag cgcaccatgc cgaacttgct ggcgatcacg acctcgtccc
     7621 ggcgtcccgc gacggcccgg ccgagcagtt cctcgcccgc gcccaggccc tggacgtcgg
     7681 cggtgtccag cagggtgacc ccggcgtcca gggcggcgcg gatggtggcg accgcccggg
     7741 ccgggtccgg gcggccgtag aaggccgtgg tcggcaggca gcccaatccc tgggcgctga
     7801 cgtgcagttc acgcagggtg cggacgagtg gacgcgggga agcgggcatg gcggtacctc
     7861 cggtgcggac gccgctgggc ggggcgagcg gcaaggacag gggagcgctg agggagccag
     7921 gggtctcccc cgggcgaagg ctgggccggg tgcggaaacg ccgcggcgcg aggacggcgg
     7981 ggcctgtcgg ccccggggcg tggcatggcg gtccgctgcg gaagccggcc cgcagcacgg
     8041 tagccgccgg cgccccgggg ccacaacgcc ctccttttca agcgcttgac aaagcgctgg
     8101 cgtaccgcgt gcaccggacc gcagcatgcg gcggccgtcc gcaaggggaa cgtccacagc
     8161 cgtgcaaggc ccgctccgca tggtgagcac ggcgtcccga ccggcccgtg ccgtcggggc
     8221 tccggcccgt gcggccgatc cgcccggtgt cgtcacagtc ccccccacat atgaggagct
     8281 gtcatgtccc gtgtgtccac cacccccggt acgaatccga cgaccgcgca cgccctgctc
     8341 cagcgcctgc gggaccacgg agtgcagacc gtgttcggcg tggtcggccg ggaggccgcg
     8401 tccatcctct tcgacgaggt ggagggcatc gacttcgtgc tgacccggca cgagttcacc
     8461 gccggggtcg ccgccgacgt actggcccgg atcagcggcc ggccgcaggc ctgctgggcc
     8521 acgctgggcc cgggtatgac gaacctgtcc accggtgtcg ccacctcgat cctggaccgc
     8581 tcgccggtca tcgcgctcgc cgcccagtcc gagtcgtacg acatcttccc caacgacacc
     8641 caccagtgcc tggactcggt cgccgtgatg cgtccgatga ccaagtacgc ggtggagctg
     8701 cagcgccccg atgacatcac cgacctcgtg gactccgcgg tcgccgccgc gaccaccgag
     8761 ccggtcggcc ccagcttcct ctcgctcccg gtcgatctgc tcgccggcga ggtcgacacc
     8821 acgcaggagc gtccggcggt gcgcgccccc ggaaagccgg tcggcgcggt ccaggacggc
     8881 tggcaggccg aggcggagcg gtccgccgag ctgctcgcgg ccgccgagca cccggtgctg
     8941 gtggtcggtg ccgcggcgat ccggtccggt gcggtaccgg ccatccgcgc cctggccgag
     9001 cgtctgaaca tcccggtcat caccacctac atcgccaagg gggtgctgcc gcacggccac
     9061 cggctcaact acggtgcggt caccggctac atggacggga tcctctcctt cccggcgctg
     9121 gagaccctgt tcggccccgc ggacctgatc ctcaccctcg gctacgacta cgccgaggac
     9181 ctgcggccgt cgatgtggca gcgcggcggt gcgaagcaga ccgtccgggt ctcgccgacg
     9241 gtcaaccccg tcccgcgggt ctaccggccc gacgtggacg tggtcaccga tgtgctggcc
     9301 ttcgtcgagc acctggaggc ccacacgggc caggtggcgg cgaagacccc gcacgacatc
     9361 gccccgctcc gtgagcggat cgccgagttc ctctccgacc ccgagcgcca tgcggacggt
     9421 atgcgggtcc accaggtgat ggactgcatg aacacggtga tggccgagag cgccgagccg
     9481 ggcgagggca ccatcgtctc cgacatcggc ttcttccggc actacggagt gctcttcgcc
     9541 cgcgccgacc agccgttcgg cttcctgacc tcggccggct gctccagctt cggctacggc
     9601 atccccgccg cgatgggcgc ccagctggcc cgcccgggac agcccacctt cctcatcgcg
     9661 ggcgacggcg gcttccactc gaacagctcg gacctggaga ccatcgcccg gctcaacctg
     9721 cccatcgtca ccgtggtggt caacaacgac accaacgggc tgatcgagct ctaccagaac
     9781 atcggccacc accgctccca cgacccggcg gtgaagttca ccggtgtcga cttcaccgaa
     9841 ctggccaagg ccaacggggt ggaggcggtg cgggccggca gccgcgagga gctgctcgcc
     9901 gcgctgcgca agggtgccgg tctggggcgg ccgttcctca tcgaggtccc ggtgaactac
     9961 gacttccagg ccggcggctt cgcggccctg agcatctgac atggagcgga ccctgcccgc
    10021 cgccaccggt ttcctggccg ccgtccatca ggacgggggc cgggccccgg cccccgtctt
    10081 cgcctcgctg gggtcctgcg ccctggagcg ggaggaacgg cacggccaca cgctgcacac
    10141 cggcctgctg cacaccggcg caccggaagc cgcccgggcg tacggaccgc gctgcgcggt
    10201 ggtgttcgcc ggagagctct acaaccaggc cgagctgcgg tcgctgctgc cgcccggcgc
    10261 cgggccggac ggtgacgccc agctcgtccg cgcgctcttc gacatctacg acctgcatgc
    10321 gttccggctg ctcaacggcc gcttcgccgc gctggtgcag ggcgaggggc gggtgctgct
    10381 cgccaccgac cacgcgggct cggtgccgtt gtacctgacg gccgcgccgg gccgggtgct
    10441 ggccgccacc gaggccaagg cgctgcgtac cgcccccacc gggcgtccgc tgcccgccgc
    10501 ccgcccggtc cgccgtctgc ccggggtcca ccaggtcccg gccggcacgg tgctggaggt
    10561 cgccctcggc acgggaggct gcaccgcgca ccgcacctgg gcaccgccgc tctcccgccg
    10621 gatcctgccg gaggacgagg cggtggcggc cgtccgccgg gccctggaag acgcggtcca
    10681 ggtccgtatg ggcccggagg cgccgctggt ggtgctctcc ggcgggatcg actcctccag
    10741 cgtcgcggcg ctggccgcag gccgggcggc cggcccggtc gacaccgtct cgatgggtac
    10801 ggacgaggcc gatgagttcc cgcaggcccg ggtggtcgcc gcacacctcc aaaccgcgca
    10861 ccgcgaactc accatcccca ccgacgacct gctgcgccgc ctgccgcaca cggtctgggc
    10921 ggcggagtcc ctggaccccg acatcatcga gtacctgctc ccgctgaccg ccctgtacct
    10981 gcgcctgggc gacaccgggc ggcgcatcct caccggctac ggcgccgaca tcccgctggg
    11041 cggcatgcac cgcgaggacc ggctgcccgc cctggacacc gcgctcgccc acgacatgga
    11101 gaccttcgac ggcctcaacg agatgtcccc ggtgctctcc ggcatcggcg gccactggtc
    11161 cacccacccg tactgggacc gcgaggtgct ggacgtcctg gtccccctgg aggcggggct
    11221 gaagcgccgc tacggccagg acaagtgggt gctccgggcc gcgatgggcg atgtgctgcc
    11281 gcaggagacc gtgctgcgcc ccaagctcgg ggtgcacgag ggatccggca ccacctcgtc
    11341 gttcagccgg ctgctcaccg ccgccggagt ccccgagggg cgggtgcacc acgccaagcg
    11401 cctggtcgtc caggagctgt tcgaccaggt ggtggtggcc gggcggcacc cggacgaggt
    11461 ggccaccgag gaagtggtgc agctcgccgc cggccagctg gagagccgca cacagcccat
    11521 ttcgtgacga cacgtcaccc cgcgcacaga cgaaggagca accagggcgt ggaacgcatc
    11581 gacaccaccg tctccccccg ctacgcgcag atccccacct tcatgcggct gccgcacgat
    11641 cccgccccgc gcggccggga cgtcgtggtc atcggcgccc cgtacgacgg cggcaccagc
    11701 taccggccgg gggcccgctt cggcccccgc gccatccgca gtgagtccgg gctcatccac
    11761 ggggtgggca tcgaccgcgg accgggcacc ttcgacctga tcagctgcgt cgatgccggc
    11821 gacatcgatc tgaccccgtt caacatgcac atcgccatgg acaccgcaca gcgtcggctg
    11881 gccgaactgc tcgccgacaa cgcggcgttc ctcatgctcg gtggcgacca ctcgctgacc
    11941 ctcgccgcgc tgcgggccgt ctccgcgaag cacgggccgc tggccgtcct ccacctggat
    12001 gcccacagcg acaccaaccc cgccttctac ggcggcgaat accaccacgg cacgcccttc
    12061 cgccacgcca tcgaggagaa gctggtcgat ccgcagcgga tggtgcagat cggcatccgg
    12121 gggcacaacc cgcagcccga ctcgttggac tacgcccgcg ggcacggcgt gcacatcgtc
    12181 accgccgaca ccttcgccga cctcggcaac gacgccgcca cccggctggt gcgggacatc
    12241 gtcggcgacg cgcccctcta tgtgtcggtg gacatcgacg tcgtggaccc ggccttcgcc
    12301 ccgggcaccg ggacgccggc ccccggcggc cccagctccc gggaggtcct ggcgctgctg
    12361 cgcggcatag gggacctgcg gccggtcgga ttcgacgtca tggaggtgtc gccgctctac
    12421 gaccacggcg gcatcacctc cgtcctggcc accgaaatcg gcgcggagct gctgtaccag
    12481 tacgcccgcg cacacgtcca agagcacgcc taggaaagga aatccccgtg acagtcgtgg
    12541 actgcaccgc tttcgccggt gagctgcgcg ccctcgccgc gcggctgccg cagacgcccc
    12601 gcgcggacct ggacgccttc ctggaatccg cgcagacggc cgccaccgcg ctccccggcg
    12661 ccctggcgac cgcgctggac accttcaacg ccgagggcaa ccaggacggc tatctgatgc
    12721 tgcgcggcct cccggtggag gacgaggcgg ccctgccgcc caccccgacc agcaccccgg
    12781 ctcccacgga ccgcccgctg ctgaccatgg aggcgatgct cggtgtcgtc ggccgccgcc
    12841 tgggcctgca caccggctac aaggagctgc gcgcgggcac cgtctaccac gacgtgtacc
    12901 cctcccccga cgcccactac ctgtcgtcgg agacctccga gacgctgctg gagttccaca
    12961 cggagatggc gtaccacgtc ctccagccca actacgtgat gctggcctgc acccgggccg
    13021 accacgagcg cacggcggcc accctggtcg cctcggtccg caaggcgctg ccgctgctct
    13081 ccgacggggt gcgcgagcgg ctcttcggac ggaagatgcc gtgctgtgtg gacgtgtcgt
    13141 tccgcggcgg ggtgccggac ccgggggcca tagcccaggt cacccccctg tacggggacc
    13201 ccgaagaccc cttcatcggc tatgaccgtg agctgctcac cccggacgtc ccggaggacg
    13261 tggcggcggt cgccgcgctg tcgaaggcgc tcgacgaggt caccgaggcg gtgtatctga
    13321 cgcccggtga tgtgctgatc gtcgacaact tccgtaccac gcacgcccgt accccgttct
    13381 cccctcgctg ggacggccgg gaccgctggc tgcaccgcgt ctacatccgc accccccgca
    13441 acgggcagct ctccggcggg gagcgcgcgg gcgacgtggt cgccttcacc ccgcgcggct
    13501 gagcgcacca ccagaacgga gccgggcggc gggggccgcc acaactgccc cgccgcccgg
    13561 ctccgttccg cactccggca acggaacatg gtatggatca gcgggacggc ccagcgccgc
    13621 accccagccc gccccttcgg tacccgggag acgaacaggc atgacggaca gcaataccta
    13681 cgaaccgcgg gggttcgcgg tgcacaccgc gcccgtgggc ctcggggacg acggacggga
    13741 cgatttcacc gtcctgctct ccaccgcacc ggccacggtg agcgcggtct tcacccgctc
    13801 ccgtttcgcg gggcccagcg tggtgctcag ccgtgccgcc gccgcggacc accgcgcccg
    13861 gggcgtggtg gtgctcgccc gcaacgccaa tgtcgccacc ggcgcggagg gcgagcgcaa
    13921 cgcccgcgag gtgcgggccg cggtggcgca ggccgcgggg ctgcccgagg aggagctgct
    13981 gatcgcctcc accggcgtca tcggccgcca gtacccgatg ccggccctcc gcgaccacct
    14041 gaagaccctg accgtgccgt tgcccgaggg cggcttcgac cgggcggccc gggcgatcat
    14101 gaccaccgac acccggccca agcaggcgtg ccggcgggtc ggtgacgcgg tggtggcggg
    14161 catcgccaag ggtgtcggga tgatggagcc cgatatggcc accctgctca ccttcttcgc
    14221 cacggacgcg cggctggacc cggcggagca ggaccggatc ttccgccggg tgatggaccg
    14281 tacgttcaac gccgtcagca tcgacaccga cacctccacc agcgacaccg cggcgctgtt
    14341 cgccaacggt ctggcgggcg aggtggaccc ggcggccttc gaggaggcgc tgtacgaggt
    14401 cgcgctgacg ctggtgaagg acatcgcccg ggacggcgag ggcgccggca agctgatcga
    14461 ggtgcgggtc cgcggcgccc gggacgacgc gcaggccaag cgggtcgcca aggccgtggt
    14521 caactccccg ctggtcaaga ccgcggtgca cggcggggac cccaactggg gccgggtcgc
    14581 catggcgatc ggcaagtgct ccgacgacac cgacatcgag caggaccggg tggtcatccg
    14641 cttcggcgag gtggccgtct atccgcccgg cctgcccggg gcgcggagcg aggacgaggt
    14701 gcgggacgcg gtcgccgccg aactggccgg cagcgaggtg gtcatcggca tcgacctcgg
    14761 catcgcggac ggcgccttca ccgtgtacgg ctgcgacctg accgagggct acatccggct
    14821 gaacgccgac tactcgacct gatcgccacc cggcccgggc gggcgcggac ggtaccccgt
    14881 tgtaccgtcc gcgtccgccc gggccgccgg gtgtcagccg tcgcaggccg gtaccgtcgc
    14941 ggggcggcgg gccaggagac ggcgcagcgc agtgccgacg aactcccggt cggcggcgtc
    15001 cgccccggcc cccgcgagat gaccccacac ccccggaatc acctccagca cggcgtgcgg
    15061 cagcgtccgc gccacccgtt cctcgtccgc ggcggcgaag cactggtcca gggcaccggg
    15121 cagcaccgcc gcctcggccg tgaccgaggc cagcgccgct tccgcgctgc cgccggaccc
    15181 cggggtcgcg cccacgtcgg tgctctccca ggtgcgcacc atggccagca gatccgcggt
    15241 ggccgggccc gccacgaaga actcctccca gaacccggtg aggtagtcct cccgggtggc
    15301 gaagcccagt tcccggtacg tctgccgcgc ccagaagggg tgcgaggtcc cccatccggc
    15361 gaagagccgt ccggcggccc gccgcccccg ctccgcgcca ccgtcggcgg tcagcgcggc
    15421 ggccaggccg gccaggaaga cctggttgtg ctcgctggtc accggggcgc cgcagaccgg
    15481 cgcgatccgg cgcaccatcc gcggatgcga caccgcccac tggtaggtgt gcgccgcgcc
    15541 catcgaccag ccggtgacca gggccagctc ccggacgccc aggtgctcgg tgagcagccg
    15601 gtgctgtgcg gcgacattgt cctgcggggt gatcagcggg aagcccgccc cggaggggtg
    15661 gttgctgggc gagctggaga ccccgttgcc gaacagcccc gcggtgatga cgcagtaccg
    15721 gcgggtgtcc agcggccggc cctccccgat cagccagtcg tagccggtgt ggtcaccgcc
    15781 gaagaacgac gggcacagca cggcgttggc gccgtccgcg tccagcgtcc cgtgcacggc
    15841 gtagccgatc ctggcatcgg tgagggtctc cccgctgagc agcggcaggg cgtcgagctc
    15901 gaagatgcgg tgctccaccg cggtcctcct tgtggtccgg tgcggccggc ggtgcgcgga
    15961 gcacgtcacc gagcgccggg gagtgccccg caccggccgc cgggacggga tgaactgagc
    16021 cccgttcaga gccagttggg cgcgatctcg gtggcccaca gctccaggct gcgcatctgc
    16081 acatcgtgcg gaatgagccc ggagtactgg cactgcagca ggtactccgg gtcgtggtgc
    16141 gccaccagct tctcgatctt gcggttgatg tcgtcgggcg taccgaccca ctccaggccc
    16201 cgctcgacca gcgtcccgta gtccgacccg atcggcccgg tctcgccctc gttccgcagc
    16261 gcctcggtga agcccatggg gccgaaccag ttctcgaaga tgaaaccgcc gccgcgggcc
    16321 gcccagtggt gggcctcatc ggcgtcccgg gacaccagga cgtccttcat cacgcccacc
    16381 cgctcaccgc gccgcagcgt gccgtgcccc gccgcctcgg cctcctcctg gtagaggtcc
    16441 atcagacggc ggacgacgcg gtcgtcggtg ttcatcagga tcggcaccac gccctcccgg
    16501 gcgcagaacc ggaaggtgtc ctcgctgaag ctgaacggct ggaacaccgg cgggtggggc
    16561 cgctggtagg gcttgggggc gatacccacc tcctggacca ccccgtcgtc gtccagcccg
    16621 cggccgtacc ggcgcaccgc ctcgtagggg aactccaggt ccttcaccgg gatcgtccac
    16681 cgctcgcccg agtgcgagaa ggtctcggtc gtccacgcct tcttgaggat ctcccagtgc
    16741 tcctcgaaga gcgcacggtt gcgccggtca ctctcgccgg cgtcggagag cgtgccgccc
    16801 acgccgtaca cctggcccat gacctcggcc cagcgcttct ggaacccccg cgcgatgccg
    16861 acgaaggtcc ggccgcgggt catgtggtcg agcatcgcca ggtcttcggc gagccgcagc
    16921 ggattgtgga agggcaggat gttggccatc tggccgaccc ggatgtgctt ggtctgcatg
    16981 cccagataca ggcccagcat caccgggttg ttggacacct cgaagccctc gacgtggaag
    17041 tggtgctcgg tgaaggagag cccccagtaa ccgagttcgt cggccgcctg cgcctggcgg
    17101 gtgagctgcc agagcatgtt ctggtagttc tgcgggttga cgcccgacat accgcgcagg
    17161 atctgggcat ggctgccgac cgtgggcaga tagaaaagga tggacttcac cgtggtcctc
    17221 tcggttcgca gagccgacgc atggctgtgt gctgtaggcg gctcgaccgt cccaccggtc
    17281 tcttgacatc catttgatgc ggcgcctgtc gggcgccccg ctccggcggg cccgggcggg
    17341 gccgcacgcc ggccgggcgc agcggtacgt ccagcgggtg gcaagccgtg gcggggagcc
    17401 tggagacgcg ccatcgccgt cccgaaggag cccgccttgt cctcagaccg ccccgccccg
    17461 tccggagcgt ccggcgccga actcgccgcc acggaccgcg ccaccctgat ccaccccacg
    17521 ctgcccgcgc accgcaccga ccggaccgtg ctggtctccg gctccggcag ccgggtccgc
    17581 gacgcccacg gccgggagta tctggacgcc tccgccgtgc tcggggtgag ccaagtcggc
    17641 cacggccggc aggagctggc gcaggccgcg gccgagcaga tgacccgcct cgactacttc
    17701 cacacctggg gccccctcag caacgaccgt gcggtggagc tggccgcacg gctggccgga
    17761 ctgagcccgg agccgctgcg ccgggtgtac ttcaccagcg gcggcgccga gggcaacgag
    17821 atcgcgctgc ggatggcccg cctctaccac caccggcgcg gcgagccgca gcggacctgg
    17881 atcctctccc gccggatggc ctaccacggc atcggctacg gcagcggcgg agtctccgga
    17941 ttccccgtct accacgacgg gttcgggccc tccctcccgg acgtccactt cctgaccccg
    18001 ccgcacccgt accgccggga gctgttctcc ggcgccgagg tgaccgactt ctgcctggcc
    18061 gagctgcgcg agaccatcga gcggaccggc ccggagcgga tcgccgcgat gatcggcgag
    18121 cccgtcatgg gcggcggcgg cgcagtgatc ccgcccgccg actactggcc gcgggtcgcc
    18181 gaactgctgc gctcctacgg catcctgctg atctccgatg aggtggtcac ggcctacggg
    18241 cgcctcgggc actggttcgc cgcggagcac ttcggcgcgg tccccgacat catggtcacc
    18301 gccaagggcc tcacctccgg gtacgtaccg cacggcgccg tcctgacgac cgacgaggtc
    18361 gcggccgaag tgaccggaga ccacggcttc cccgtcggct acacctacac cgggcacccg
    18421 acggcctgtg ccgtggcgct ggccaacctg gacatcatcg agcgcgagaa actgatggcc
    18481 aacgccaccg tggtcggtga ccacctgggg tggcggctgg cggagctgac cgacctgccg
    18541 gtcgtcgggg aggtgcggca gctcgggctg atgctggcgg tggagctggt gtccgacaag
    18601 gacagccgcc ggccgctgac gggcggcacc ctcgccgtgg cggacgcgct gcgggagcag
    18661 gccggcatcc tgctgcgcac caacccgaac gcgctggtga tcaacccgcc gctggtcttc
    18721 agccgtgccg acgcggacga actcgtggac gggctgcggt ccgtgctcag ccggaccggt
    18781 ccggacgggc aggtgcactg acgttccggt ccggacgtgc aggtgcactg atctaccggt
    18841 cccgtcgcac accggtactg ctgccccggt gtgtggcggg acgtcaaacg gttctgcaag
    18901 cgggtgccaa gggccgcggg gcagtctggc ggggccgtgc cgggcggcgg ccgggccgcg
    18961 cccggaccag cccggtccat ctgcgtccgc acctccggag accccatgcc acagcgcccg
    19021 aaaatcgtcc tcgtcggtca gttgtccagc tttccctggg tgttcgactc cgctgagcgc
    19081 gccggtatcg acctggtgct cgtgccccgg ggtgacgact ccgtggagtc cgccgggcgc
    19141 gcgaagtcgg tggtcgaggt cctgccgctg gacatcgacg gggacccgga gtcggcgctg
    19201 tccacgctcg tcgagcgctt ccggcgcgac cccttcgacg ggatcatgcc gggcaacgag
    19261 aaggtggtgc ccttcgtggc ccgcgccgcc cggatgctgg gactccccgg cctgcccgag
    19321 gaggtggcgg cggtggtccg ggacaagcgc agcatgcggc ggctgctgcg tgaggcggga
    19381 ctgggggcgc ccggcttcgt cagcctggac ggcccggacc gctgggcgga cgcactgacc
    19441 ctgcgcttcc ccgtggtggt caagccggcg aacggctact ccagcctcgg cgtggtccgc
    19501 gtggacgaca aggaccagct ggtgccggcc gtcgcccgga catgggagct gtgcgagacc
    19561 gagctgcggc aggccggcgg gccggccgac ggggtcggcg tgctggtcga ggagtacctg
    19621 gacggtccgg aggtcgccgc cgagtccctc gtccaccagg gcagggtgcg ggtctgtgcc
    19681 atcgagtgga agggggagat gaccgggccc tacttcgagg agaccacggt gcgcgcgccc
    19741 gcccaactgc ccgcggacgt actggccgcg atcgaggcgg aagtgatcgg cgcgcaccat
    19801 gccttcggcg tcaccgaagg cgccacgcac acggagctgc ggctgatcgg tggcgtaagg
    19861 ccggtcctgc tggagatggc cgcgcgcatc ggcggcgcgg gcgtcaacca ctacctgacg
    19921 cacattgccg gcgggatcga cctggccgcc gaggcgctgc gcatccacct cggccaggag
    19981 ccggtctgct ggagccagga gccggtgccg acgggtcatg cggcggccta ctcggtgccg
    20041 gtcggcaagg gcggacggat cgtccgggta cacgggctgg acgccgtacg cgccgacccc
    20101 cgggtcgacc aggtggtgca gaccgtcggc cccggcgccc tgctccgccc ctacccggac
    20161 tgggccgggt acccggccat cgtcctgtcc caccatgagt cggacgccgc cgccgtggag
    20221 ttccgcgacc acctggtgcg gaccctgcac gtcgagtacg aggaggagag ctgagcgcgc
    20281 agcagccggg cgggaccgtg gtgaaggcgc tccgtacctc cctgggcggg ctgccgcgcc
    20341 cgttctggtg gctctggggc gagaccctca tcacctccgc cggcggattc gtcctgccct
    20401 tcctggcgat ctacctgacc agcgtgcgtg ggtactcggt ttccttcgcc agcctggccc
    20461 tgacggtgtt cggggtcggc agcggaatcg cctcgctggc cggcggtgtg ctcgcggacc
    20521 gtctcggccg ccgggtggtg ctgctggcga gcgaggtgct ggccgtggtc ggcatgctgg
    20581 cactcggcac ggcacgcacc cagatcatgg tgctggtcgg cacgctcgtg gtgggggtgg
    20641 ggctgaacgc cacccggccc gcgcgggcgg cggccgtcgc ggacctggtg agcgaggagg
    20701 gccgcccccg ggcgttctcg ctgctctact ggggcaccaa cctggggtcc tccgtcgcgg
    20761 cggtcagcgc cggcctcgcc gccgagcacg gcttcttcct gctgttcgtg gtcaatgcgt
    20821 gcgccaacct ggccgcggga gccgtggtct accgctgcgt cccggagacc cgcccggagc
    20881 cggtgccgcg tcgcggcagc aagtccctgc cggccggggc cgtccaccgc gaccggccgt
    20941 tcctggtgct gctcgggtcg gtgctgctgc tggggatact gttccagcaa ccgctggtcg
    21001 ccctcccgct gaccatgacg gccgacgggc tctccccggc cggctacgga ctggccatga
    21061 tgatgaacgg cctggtcatc gtcatcttcc agataccgct gacccgcctc gcgggacgta
    21121 tacggcccga gttcgcgctc gccgcggcca ccgtgctcac cggtatcggt ctgggctgca
    21181 ccgccgccgt ccactccgtg ccggggtacg cggcgaccgt ggtgctgtgg agcctgggcg
    21241 agatcgtgat ctggccgacc tgcatgacct tggtcgccgc cctggcgcca ccccaccaac
    21301 agggcgccta ccagggctgg ttcctctccg tgtggagcgt ctccgtcgcc ctggcgcccc
    21361 tgttcagctc acaactgatc ggggccttcg gcggcaccgc cgtggtctgg acggcctgcc
    21421 tggtcctggc actcgtggcc gccaccggcc atctcgtcct cgcccggctc cgccgaccgg
    21481 tgtgacgagg ggaaccggct gacggggaac cggctgatct cgtcagcgct ttccgggcga
    21541 gggcgttcct ccggcggagg cggggcggcc ggccgtccgg ccgccccgct caccacgcat
    21601 ccttacccga gctgccggcc gatctcgcgg gagaaggccg cgacccgggt gtagacgccg
    21661 gtcgtggggg tggtggcatt gccgccggcc agccagctga cgatcccgat cagcttgccg
    21721 ccggcgacga gcgggccgcc gctgtcacct tcggcatggt gggcgccggt gaccggatcg
    21781 ttggcgcaga cgtgcatttt ggggtcgatg tcgccccagg ggttgagccg ttggcatgtc
    21841 cggtcggcca ggacccgcag gttcgccgac cggagcacgt tcgcctcacg gccctcgttg
    21901 tccagcagac cccagccatg gacccgggca cgggtgccgg ggcggtacgg accggtgtcg
    21961 gcagcggtgg ccacgggcag cggggtgtac tgcggtggca tcggcttgtc gagcgtgagg
    22021 acggcgacat cgttctccag gtggcggccg aatcgcggat ggatccaggc cttggtcacc
    22081 ttgcgcatcc ggccgtcgtg gcggcgcaga tcggtacggc ccgcgaccac ccccagatcg
    22141 gtgggggcct cgtcgacgac gcagtgggcg gcggtgacga ccttcctcgg agtgaccagg
    22201 gtgccgccgc agaactgccc cgagcgcgga taggtgtcgg tctgccgcca caggttgatc
    22261 gtgacggtcc acggtgccgc tgccgtactg gatttctgtc cgccgatgac ggcctgggcg
    22321 gggtgcgccg gcagcacggc gaagccggcc ccgacgagca ccatgagccc tgccaggacc
    22381 ggccaccgca ggtacccgtg tcgcgccatg tggatgctcc cctgcccgct catccggcga
    22441 tccggctctg gaggagcggg tagtaggagg ccgccttcac ggcgacgccc gggtagaggc
    22501 ggctggtaca actgccgccg ccgctgatga caccgaccag ccgcccccgc accacgaccg
    22561 gccccccgct gtccccggaa catgcgctga caccgcccgc cgggtagccg aggcacatcg
    22621 tgtaggactt ctggtaccgg cgggtgccat acgccgtgat gcactgctcg tcgccccggt
    22681 tgggtatcag cgcggtctgc agcggcggca cccggaggtc atcgtcgcgg cccgtggtgg
    22741 agccccatcc caggaccctg ttgggcgtgc cttcctcgta cagcttctgc tgcgccgggg
    22801 tggcgagcgg cagggtccgg tacggcatgg gggcgttgag ggtgaggacg gcgaggtcgt
    22861 gcgcgtaggt ggcgccgttc ccttcggtgt cggccttggg gtggatccac agcttcgcca
    22921 ccttgcgcac ggtgcccttg cgggtgtccc gcagatcctc ccgtccgccc accacacgca
    22981 cgccgtcgac ggtggccggg ctcacgcagt gggacgcggt cagcaccttg cgcggcgcga
    23041 cgagggtgcc cgcgcagtcc gggtccttca cgtcccgcga cgtcagagcg accgtccacg
    23101 gatacttctt gatctcggcc cggtctcccc cgacgacagc ggcggcgggc ggggcggacg
    23161 accccaccag cgccgccccc accaggaccg cgcccgccaa ggtgccgcgg cgggttctcg
    23221 ctttgctcat cagtcctcca ttgacgatcg aacaaagtcg cccagggaga ggccgtggag
    23281 agtaacgcgg ttgccttgcc cctccgggcg cccgcatatg gccggcatga gccagggcct
    23341 cttgacacgc ttccgctcgt gaccgggccg tgtggccccc tcggccccgt catggtgccc
    23401 gcccgcatgg tgcggccccg aagtgtggtg tcccaccaca tgtgcgcctg acctgggcat
    23461 ttctacggtg tggcgatacg tcaacgtccg cgtagccgcc cg
//
