LOCUS       NZ_CP029541            10228 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. NEAU-S7GS2 chromosome, complete genome.
ACCESSION   NZ_CP029541
VERSION     NZ_CP029541.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. NEAU-S7GS2
  ORGANISM  Streptomyces sp. NEAU-S7GS2
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9641634)
  AUTHORS   Zhang,J.
  TITLE     Streptomyces sp. NEAU-S7GS2 isolated from saline-alkaline soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9641634)
  AUTHORS   Zhang,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2018) School of Life Science, Northeast
            Agricultural University, Mucai Street, Harbin 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: AMRT Link v. v5.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003173275.1-RS_2024_05_07
            Annotation Date                   :: 05/07/2024 05:28:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,458
            CDSs (total)                      :: 8,365
            Genes (coding)                    :: 8,052
            CDSs (with protein)               :: 8,052
            Genes (RNA)                       :: 93
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 313
            CDSs (without protein)            :: 313
            Pseudo Genes (ambiguous residues) :: 0 of 313
            Pseudo Genes (frameshifted)       :: 144 of 313
            Pseudo Genes (incomplete)         :: 230 of 313
            Pseudo Genes (internal stop)      :: 21 of 313
            Pseudo Genes (multiple problems)  :: 74 of 313
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:52:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1491211
            Orig. end                         :: 1501439
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029541.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10228
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="11"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10228
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10228
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5228](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5228)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(355..369)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.34"
                     /tool="antismash"
     misc_feature    1364..1381
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            complement(1731..4016)
                     /locus_tag="DKG71_RS06060"
                     /old_locus_tag="DKG71_06060"
     CDS             complement(1731..4016)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091742.1"
                     /locus_tag="DKG71_RS06060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_06060"
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_109887783.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.8e-37, bitscore:
                     127.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPHDSAAPQQQLPPPVRGRHRPEPAPGARRTRRAAPAPKPKKT
                     KTVRTPTVLQMEAVECGAASLAMVLAHYGRHVPLEELRIACGVSRDGSRASNLLKAARS
                     YGLQAKGMQMEPAALAEVQAPAILFWEFNHYVVYDGTGRRMGRRGVHINDPDKGRRFVA
                     MEDFDTSFTGVALVLEPGESFHKGGRKPGVLGAVPARMRGTTGTLLAALLASLLLVAVG
                     AAVPALSRTYIDMFLIGNQTSLLGPLFASMAAMVALTAVLTGLQQANLLRGRIISSTLT
                     SARFLRHLLRLPVTFFAQRSPADLVQRLQSNDAVAETLARDLAAAGVDGIVVVLYAFLL
                     WTYDPQLTVIGVGIALLNVVAMRIVIRLRSTHTQKLRADSARLTNTSYTGLQLIETMKA
                     TGGENGYFRRWAGQHATTLEVQQRLGVPSAALAVVAPTLATLNSALILWIGGLRAVEGH
                     ISIGLLVAFQALVTRFTAPLTRLNGVAGRIQDFAADVARLKDVESFPVDTLYSRPEPEA
                     DTRRLKGHVTLEGITFGYSPLDKPLLTGFSLAVGPGRQVALVGGSGSGKSTVSRLISGL
                     YSPWEGTIRIDGQRLEDLSRSALAASVSFVDQDIFLFEGTVRDNVALWDPSIPDDAVIT
                     ALQDAALYDEVIAPRPDGIHSRVEQDGRNFSGGQRQRLEIARALVRRPSILVLDEVTSA
                     LDAQTEQIIMDNLRRRGCACVVIAHRLSTVRDSDEIVVLDHGVVVERGRHEDLVAAGGP
                     YAELVKEH"
     gene            complement(4013..4822)
                     /locus_tag="DKG71_RS06065"
                     /old_locus_tag="DKG71_06065"
     CDS             complement(4013..4822)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386622.1"
                     /locus_tag="DKG71_RS06065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_06065"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_093640140.1"
                     /transl_table=11
                     /translation="MQFRQQALSKLQSPEEIDLPVRFARPQGWLVLIVTVLFVVAASVW
                     AVTGTVSSTLNAPGILTHGQGSYVLQSPVAGQVTAVLAEEGKRVAAHTPVLRVRTAQGT
                     TTVVRTLAAGRLTTMVATIGSVVTTGADVASVERIARAGDPLTATLYVPAESGATVPVG
                     ASVDLTVQSVPSQQYGVLRGRVKAVGRTAQSRQRISTFLGSGQLGEEFSQHGQPVAVLV
                     QLDAAPHSKSGYAWSTSDGPPYAVDSMTPASGAVHLAAQHPIDWLLP"
     misc_feature    4787..4799
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.37"
                     /tool="antismash"
     misc_feature    4948..4960
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            complement(5001..5228)
                     /locus_tag="DKG71_RS06070"
                     /old_locus_tag="DKG71_06070"
     CDS             complement(5001..5228)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008412458.1"
                     /locus_tag="DKG71_RS06070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_06070"
                     /product="hypothetical protein"
                     /protein_id="WP_018091740.1"
                     /sec_met_domain="strepbact (E-value: 1.5e-30, bitscore:
                     104.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSTPQVQTQEISDSDLDNVSGGLVGGVVGTATSTVDSIAPVSGA
                     VGTATGLVDGVAGTDTAGVVGTATGLVAGL"
     misc_feature    5614..5623
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.17"
                     /tool="antismash"
     misc_feature    complement(5628..5644)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.58"
                     /tool="antismash"
     misc_feature    5631..5640
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.08"
                     /tool="antismash"
     misc_feature    5702..5719
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.87"
                     /tool="antismash"
     gene            5986..7017
                     /locus_tag="DKG71_RS06075"
                     /old_locus_tag="DKG71_06075"
     CDS             5986..7017
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091739.1"
                     /locus_tag="DKG71_RS06075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_06075"
                     /product="PHP domain-containing protein"
                     /protein_id="WP_109887785.1"
                     /transl_table=11
                     /translation="MEPVEALERIAFLLERQGAVSYRVQAFRTAATVIGALSADQLRTR
                     ARNGSLGRLKGLGPKTTRVIEEALAGARPEYLTHLEEEAGGPLVEGDQGQRLRRALRGD
                     CHLHSDWSDGGSPVEVMARAARDLGHAWCVLTDHSPRLTVARGLTAERLRQQLSLVAEV
                     NERLAPFRLLTGIECDILDDGSLDQEPELLERLDVVVASVHSKLRMDKAPMTRRLLEAV
                     RNPLVDVLGHCTGRQITGKPRPESQFDAGEVFAACAEHHTAVEINCRPDRFDPPRRLLR
                     QALETGTLFSIDSDAHAPGQLDWQIYGCARAEECGVPPERVINTWTERQLATWTRTGRT
                     PHH"
     gene            7079..7747
                     /locus_tag="DKG71_RS06080"
                     /old_locus_tag="DKG71_06080"
     CDS             7079..7747
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1226: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091738.1"
                     /locus_tag="DKG71_RS06080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_06080"
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="WP_109887787.1"
                     /transl_table=11
                     /translation="MDMRTEDEWVAVPPGRVTLSDRRTQRSWAVELAPYRLAPFPLTQA
                     RYAQVTGERPSSAQGDRLPVEGVSWWDAVRFCNALSAQEGLAPAYRLYPGVERIEWDTS
                     ADGYRLPTEAEWEHACRAGTTEARYGRLDEIAWHRGNSHGRMHEVGGRQPNAWGLYDML
                     GTVWEWCWDLYDAEVYGSYRVLRGGGWFDERWSCRASVRRRSHPTFRIDDVGFRVARSL
                     "
     gene            complement(7778..9136)
                     /locus_tag="DKG71_RS06085"
                     /old_locus_tag="DKG71_06085"
     CDS             complement(7778..9136)
                     /GO_function="GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA]"
                     /GO_process="GO:0006821 - chloride transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091737.1"
                     /locus_tag="DKG71_RS06085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DKG71_06085"
                     /product="chloride channel protein"
                     /protein_id="WP_109887789.1"
                     /transl_table=11
                     /translation="MSVGPAGPVGGAPTTVPQDPYALVRTRGYLKLLLVAAVIGFPVCA
                     VAFGFLALVHELEPLIYQDLPRALGFAGTPIWWPVPMLVVAGLLVGLTVRYLPGSGGHE
                     PADGLALSGAPPLSALPGVVLAALTSLSFGVVLGPEAPLIALGGGLAAGAVRLMDRGMP
                     AQTVATVGAAGSFAAVSALLGSPLLGAFLLMEVSGLGGPMLGIVLVPGLLASGLGALIF
                     TGLGDWTGLGTYSLALHDIPRAAGPTIAEFGWALVIGLAAGFAGTGVRRFARFLKGHVV
                     RHRVPATVLMGLVVGALAVAFAATTGKPSSEMLYSGQSALGSLFRDSAGYTVGALLLLI
                     LCKGLAYCASLSAFRGGPIFPALFLGAAGGVVLSHLPGLSLTAGFAMGVGAMCVAMLRL
                     PMTSVLLATLLLGKSGLTVMPLVIVAVVVAYVVVLRLTPATAPEAPAAAPHAA"
ORIGIN
        1 gccagcgcag ctcccacagg cccatggcga ggaacaccgc cccgatgacg agcagcatgg
       61 cgatcgccgc cagcgccagc ggcacactgt agaggagcag cagcaccaga ttcatcgcgc
      121 cgatggtggt ggactgcacc gccaccggac cgaggccgga cagcacccgc cggatgctgc
      181 tgatgcccat cgcggcactg gccagctctc cggtggagcg ttcggtgaag aacttcgtcg
      241 gcagccgcag cagccggtcc cacacggccg gctgcagggc gctctcgatg cgcccctcca
      301 tccgcaggac ggtgaggttc tgcagcagca tgaaggcggc ggagacaatg ctggtgatca
      361 tgacggccag ggagacctgc acgatcaggc tcttgtccgc gctcggtacg tactccccga
      421 gcaccttgcc ggtcgcgatg gggacgaggg cgccgaggcc gacggtcacc agtccgctga
      481 gggccagatt gcggacgtcc atacgggtgc cgcgcaggct gaagagcatc agccgccaca
      541 ggctcatggg ccgttccggc agcgggcggt agaacatcac ggcgcgcgct tcgaattcgt
      601 cggcgttgtc cttgccgatg cgcatccgca ggccggagac cgggttgacc gcctcgtagc
      661 ggccgcggcg ccacagcagc gccaccgggg caccggactt ggcgcgatgg cccaccaggg
      721 gcccggtgtt ggtgcgccac cagcggccct ggagccggac cgcgcgggtc cggatccgcg
      781 agctgaccgc gatccgctcg accggggtga tccggtcgtt gacggcgctc cccttcggtg
      841 gctcggtgag cgtgatgccg gccgcctccg cgaccgtgcg gcagatcgcg aaggtggtgt
      901 catcgccggt ccggtcggtc ccggcgctgc cgcgcccggc ccggtcctgc cggccgatgg
      961 acgccagcag cgcctggtcg gcgcgctcgc ggacggtttc gcccgccttg ataccggccg
     1021 ccgtacggtc ctcgtgggcg cgctccagct gctcgatcca gcggtcgacg gcggacagca
     1081 gccggtactg ctgattgacc atctgctgcc acagctcggg gtcgaccagc agatcgccgg
     1141 ccgcctccgc gctgtaggag gcgccgtact gcacgctgcc gggcgggacc ggcatccaca
     1201 ggatgtcgtc gtcggccacc gcgtcatcgc cgggccggcc gtcgagcggt gcctcgaaca
     1261 gcacaccgag gctgcgggcg gtgcccagcg cgaaggcgtg ctccagcggg gagggcgcct
     1321 cgccctggac gtcgtacgcg gggtcgtagc cgtagccgcc ctgcgtgccg tactgcggat
     1381 acgacccggt gtcgccgtac tcgggacggg gcagttcgcg cagggggatg cggcgcacca
     1441 ggcagtcctg ggagggccgg ccgagcaggg tgtgctgcgg gccggcgacc gggccgagca
     1501 gcagagtgcc cgcttcgagc cggccgagga agtgccagtg cccttcctgg gcggcgtcga
     1561 ccgcgaagag atccagcgag ccgcccgtga cgagccacag cacatgcggg ccctccaggg
     1621 gaacgctgcg cagcccggtg cagtcgacgg gtgtgccgag gctgcccagc gcatgggtca
     1681 cggcgtcggt gtcgcccggt cccacgaccg cgggcggggg tacggacacg tcagtgctcc
     1741 ttgaccagct cggcgtacgg gcccccggcg gcgaccaggt cctcgtgccg gccgcgttcg
     1801 acgaccaccc cgtggtcgag gacgacgatc tcgtcgctgt cgcggaccgt gctcagccgg
     1861 tgggcgatga cgacgcaggc acagccgcgc cgccgcaggt tgtccatgat gatctgctcg
     1921 gtctgcgcgt ccagggcgct ggtgacctcg tcgaggacca ggatgctggg gcgccggacc
     1981 agtgcgcggg cgatttccag ccgttgccgc tgcccgccgg agaagttgcg gccgtcctgc
     2041 tcgacccggc tgtggatgcc gtcggggcga ggggcgatca cctcgtcgta gagcgcggcg
     2101 tcctggaggg cggtgatcac cgcgtcgtcc gggatcgacg ggtcccacag cgccacgttg
     2161 tcgcggaccg tgccctcgaa caggaagatg tcctggtcga cgaaggagac ggaggcggcc
     2221 agcgcgctgc gggagaggtc ctccagccgc tgaccgtcga tgcggatggt gccttcccag
     2281 gggctgtaga ggccggagat cagccgggag acggtggact tgccgctgcc ggagccgccg
     2341 acgagggcga cctgccggcc ggggccgacg gccagggaga agccggtcag cagcggcttg
     2401 tcgagcgggc tgtagccgaa ggtgatgccc tccagcgtca catggccctt gagcctgcgg
     2461 gtgtcggcct ccggctcggg gcgtgagtag agggtgtcga cggggaagct ctcgacgtcc
     2521 ttgaggcggg ccacatcggc ggcgaagtcc tggatccggc ccgccactcc gttgagccgg
     2581 gtgaggggcg cggtgaagcg ggtcaccagc gcctggaagg cgacgagcag accgatggag
     2641 atatggccct cgaccgcccg cagtccgccg atccacagga tcagtgcgct gttgagcgtg
     2701 gcgagggtgg gggcgaccac ggccagcgcg gcgctcggca cgcccaggcg ctgctgcacc
     2761 tccagggtgg tggcgtgctg gccggcccag cggcggaagt agccgttctc cccgccggtg
     2821 gccttcatcg tctcgatgag ctggaggccg gtgtaggagg tgttggtcag ccgcgcggag
     2881 tcggcgcgca gcttctgggt gtgggtggac cgcagccgga tcacgatccg catggcgacg
     2941 acattgagca gcgcgattcc cacgccgatc acggtcagtt gggggtcgta cgtccacagc
     3001 aggaaggcgt agaggacgac gacgatcccg tccacgcccg cggcggcgag gtcacgtgcc
     3061 agcgtttcgg ccaccgcgtc gttggactgc agccgctgca ccaggtcggc cgggctgcgc
     3121 tgggcgaaga aggtgaccgg gagtctgagc agatggcgca ggaagcgggc gctggtgagg
     3181 gtggaggaga tgatgcggcc gcgcagcaga ttggcctgtt gcagaccggt gagtacggcg
     3241 gtcagcgcga ccatggcggc catcgacgcg aagagcggtc ccagcagcga ggtctggttg
     3301 ccgatcagga acatgtcgat gtacgtacgg ctcagcgcgg gcaccgccgc gccgaccgcg
     3361 accagcagca ggctggcgag cagcgcggcc agcagggtgc cggtcgtacc gcgcatccgg
     3421 gcgggcacgg cgccaaggac gccgggcttg cggccgccct tgtggaagga ttcgccgggt
     3481 tcgaggacca gggcgacacc ggtgaagctg gtgtcgaagt cttccatcgc cacgaagcga
     3541 cggcccttgt cggggtcgtt gatgtggacg ccgcggcggc ccatgcggcg gcccgtgccg
     3601 tcgtagacga cgtagtggtt gaactcccag aacaggatgg cgggcgcctg cacctcggcg
     3661 agcgcggccg gttccatctg catgcccttg gcctgcagcc cgtagctgcg ggccgccttg
     3721 agcagattgc tggcgcggga gccgtcgcgg gagacaccgc aggcgatccg cagctcttcg
     3781 agcggcacat gccgtccgta gtgggcgagc accatggcca gcgaggcggc gccgcactcc
     3841 acggcctcca tctggaggac ggtgggcgtg cggacggtct tcgtcttctt gggcttcggg
     3901 gcgggcgcgg cacggcgggt gcggcgggcc ccgggcgcgg gctccgggcg gtgacggccg
     3961 cggacgggcg gcggcaactg ctgctgcggg gcggcggagt cgtggggggc ggtcacggca
     4021 gcagccaatc gatcgggtgc tgcgcggcca ggtggacggc gccactggcc ggcgtcatgg
     4081 agtcgacggc gtacggcggg ccgtcggagg tcgaccaggc gtagccggat ttgctgtgcg
     4141 gggcggcgtc gagctgtacc aggaccgcga cgggctggcc gtgctgcgag aactcctcgc
     4201 cgagctggcc gctgcccagg aaggtgctga tccgctggcg tgactgtgcc gtcctgccga
     4261 ccgctttcac ccgcccgcgc agcacgccgt actgctggga cggcacggac tggacggtga
     4321 ggtcgacgga cgcgccgacg gggacggtgg cgccgctctc ggccggtacg tacagcgtcg
     4381 ccgtcagggg gtcgccggca cgggcgatgc gttccacgga ggccacatcc gctccggtcg
     4441 tgacgacgga gccgatcgtg gcgaccatcg tggtcagccg gccggcggcg agcgtacgga
     4501 cgacggtggt ggtgccctgg gcggtacgga ccctcaggac gggggtgtgg gcggccaccc
     4561 gcttgccctc ttccgcgagt acggcggtga cctggcccgc gacggggctc tggaggacgt
     4621 agctgccctg gccgtgggtg aggattccgg gtgcgttcag ggtggatgac actgtgccgg
     4681 tcaccgccca tacggaggcg gcgaccacga agaggaccgt gacgatcagt acgagccagc
     4741 cctgggggcg ggcgaagcgc accggaaggt cgatctcctc gggcgattgc agcttggaaa
     4801 gggcctgttg gcggaactgc acgacactct tccctcaact gcaacgttct ggtgcggacg
     4861 ggtggtggcc ggcgccccgg cgcccggatg gagtccgggc ggaccggggc agccggcccg
     4921 gcatgtcggc aaggaggggg cgccgacctg ccgttgtcac cgttcaaagc cggctgtgcc
     4981 gctcagcggc acagaagggc tcagagaccg gcgaccaggc ccgtggcggt gccgacgacg
     5041 cccgcggtgt cggtgccggc gacaccgtcg accaggccgg tggcggtgcc cacggcgccc
     5101 gagaccgggg cgatggagtc aacggtgctg gtggcggtgc cgaccacgcc gccgacgagg
     5161 ccaccggaca cgttgtccag gtcgctgtcg gagatttcct gcgtctgaac ctggggggtg
     5221 gagttcatga tgattccctt cggatgaata tctcgaaaaa gctgcgtccg aaccgtccgg
     5281 tggggggccc ggccgcagca gcggcagtcg ggttcccgaa atcgggaacc ggggggtgac
     5341 tcccgcagtg cgaaggatca aagcatgcag gtgcgttgcg ctgctaatcg ggtagccgca
     5401 gatccgggcg cgatcgcccc tttgaaatac ctgacgtgca cgcacgtcca tgacttggtg
     5461 gcagcttctt cacatctcct tcggtttctt ttccgggacc tcggcaagcg cccgttcggc
     5521 gaactggaca ttccgtcacc aaagcgctaa gtcgcaggtc agcgtgggga tgggtcacag
     5581 gagaccgtgt gccgactgca cattcggtgt gcagattttt tgaaggccgc cgatttttgc
     5641 ggcacctcga cgcggtgcgg gaagacacct ccggcgcgcg cttccggcgg agccgcgccg
     5701 aatgttgcat gggcattaag tgtgcccgat tcgcccggag ttcatgggcg ctatttgagg
     5761 tcttgaacgt attgaatgga cgcatcgccg ctatccgtat gccatttcca tggaaacgga
     5821 tcgagcgctc ggagaacgga cataaccgca taacggaggg tcttcggacc cgtcggtaat
     5881 gggcgattac cgccggaaac accggcaccc cggtggcagc cgctcagcgg ctgcggcacc
     5941 gtgagagaga cgctgcgggg ccggcgcccc gggaaggagc cgtacgtgga gcccgtcgag
     6001 gcgctggagc ggatcgcctt tctgctggag cggcagggag cggtgagcta ccgcgtccag
     6061 gcgttccgta cggccgcgac ggtgatcggc gcgctgtccg ccgaccagct gcgtacccgc
     6121 gcccggaacg gttcgctggg acgcctcaag gggctggggc ccaagaccac ccgggtgatc
     6181 gaggaggcgc tcgcgggcgc gcggcccgag tatctgacgc accttgagga ggaggcgggc
     6241 gggccgctgg tggaggggga ccagggccag cggctgcgta gggcgctgcg cggtgactgc
     6301 catctgcact cggactggtc ggacggcggc agcccggtcg aggtgatggc gcgggccgcg
     6361 cgcgacctgg gacacgcctg gtgtgtgctg accgaccact cccccaggct caccgtcgcc
     6421 cgcggactga ccgccgagcg gctgcggcag cagttgtcgc tggtggcgga ggtgaacgag
     6481 cggctggcgc cgttccggct gctgaccggg atcgagtgcg acatcctcga cgacggctcg
     6541 ctcgaccagg agccagagct gctggagcgg ctcgatgtgg tggtcgcctc ggtgcactcc
     6601 aaactgcgga tggacaaggc gccgatgacc cggcggctgc tggaggcggt ccgcaacccg
     6661 ctggtggacg tgctcggcca ctgcaccggg cggcagatca ccggtaaacc gcgcccggaa
     6721 tcgcagttcg acgccggtga ggtgttcgcg gcctgcgccg agcaccacac cgcggtggag
     6781 atcaactgcc ggcccgaccg cttcgatccc ccgcgccggc tgctccgcca ggcgctcgag
     6841 accggaaccc tcttctccat cgacagcgac gcccacgcac cgggccaact ggactggcag
     6901 atctacggct gtgcccgtgc cgaggagtgc ggtgtaccgc cggagcgggt catcaacacc
     6961 tggacggagc gccagttggc cacctggacc cggacgggcc ggaccccgca ccactgaccg
     7021 cgcccggcgc cgtactcccg cgctccgcgc agagcggcgt tgctaccctc gcctcctcat
     7081 ggacatgcgc acagaagacg agtgggtcgc cgtcccgccg gggcgggtga cgctgtcgga
     7141 ccggcggaca cagcgcagtt gggcggtgga gctcgcgccc taccggctcg cgccgttccc
     7201 gctcacccag gcgcggtacg cacaggtcac cggcgagcgg ccgagcagcg cgcagggcga
     7261 ccggctcccc gtcgagggcg tctcgtggtg ggacgcggtc cggttctgca acgccctgtc
     7321 cgcacaggag gggttggcgc ccgcgtaccg cctgtacccc ggcgtcgagc ggatcgagtg
     7381 ggacacctcc gccgacgggt accggctgcc gaccgaggcc gagtgggagc acgcctgccg
     7441 tgccggtaca acggaggcgc ggtacgggcg gctcgacgag atcgcctggc accgcggcaa
     7501 ctcgcacggg cggatgcacg aggtgggcgg cagacagccc aacgcgtggg gcctgtacga
     7561 catgctgggc actgtgtggg agtggtgctg ggacctctac gacgccgagg tctacggcag
     7621 ctaccgggtg ctgcgcggcg gcggctggtt cgacgagcgc tggagctgcc gggcctcggt
     7681 gcggcgccgc agccacccga ccttccggat cgacgacgtg gggttccgcg tcgcgcgttc
     7741 cctctgaccg ggccggcggc aaggctcccg cccgtcgtca ggcggcgtga ggggcggccg
     7801 ccggggcttc cggtgcggtg gccggcgtga ggcgcagcac cacgacgtag gcgacgacca
     7861 cggcgacgat cacgagcggc atcaccgtca gaccgctctt ccccagcagc agcgtggcca
     7921 gcagcaccga ggtcatcggg agccggagca tggccacgca catcgcgccg acgcccatcg
     7981 cgaagcccgc ggtgagcgac agacccggca ggtgggacag cacgacaccg cccgccgcac
     8041 cgaggaacag cgcggggaag atggggccgc cccggaaggc gctgagcgag gcgcagtacg
     8101 ccaggccctt gcacaggatg agcagcagca gcgcgcccac ggtgtagccg gcgctgtccc
     8161 ggaacagcga ccccagcgcc gactggcccg aatagagcat ctcggaggag ggcttgccgg
     8221 tggtggcggc gaacgccacc gccagtgcgc ccaccacgag gcccatcagc accgtggccg
     8281 gtacccggtg ccggacgaca tgtcccttga ggaaccgcgc gaagcgccgt accccggtcc
     8341 cggcgaaacc ggcggccagt ccgatcacca gcgcccagcc gaactccgca atcgtcggtc
     8401 cggcggccct ggggatgtcg tgcagcgcga gcgagtacgt accgagcccg gtccagtccc
     8461 ccagcccggt gaagatcagc gcccccagac cggacgccag cagaccgggc accagcacga
     8521 tccccagcat cggaccgccc agccccgaca cctccatcag caggaacgcg cccagcagcg
     8581 gcgagccgag cagggcgctg accgccgcga agctgccggc cgcgcccacc gtcgcgaccg
     8641 tctgcgccgg catgccccgg tccatcagcc gtacggcgcc cgcggccaga ccgccgccga
     8701 gggcgatgag cggtgcctcg ggcccgagca ccacgccgaa gctgagggag gtcagggccg
     8761 cgaggacgac accggggagc gcggagagcg gcggcgcccc gctgagcgcc agcccgtcgg
     8821 ccggctcatg gcccccgctg ccgggcagat accggacggt gagcccgacg aggagaccgg
     8881 ccaccaccag catcgggacc ggccaccaga tcggcgtccc ggcgaagccc agcgcccgcg
     8941 gcaggtcctg gtagatcagc ggttccagct cgtggaccag cgcgagaaag ccgaacgcga
     9001 cggcgcagac cgggaagccg atcaccgccg ccaccagcag gagcttcaga tatccgcggg
     9061 tgcgcaccag cgcgtagggg tcctggggca cggtggtcgg cgctccgccc accgggccgg
     9121 ccgggccgac cgacatgcgc ctcgcctcct cggaaccggg gatgccccgg cgcccgcccg
     9181 ggccgccgcc gtgatgagcc tgccacggcc ggtccgggcc ggcacctcgg gcgcggccgg
     9241 acagggagcg gtggcggtgc ggtgtgtgcg gcccgccgtc gccgtggtgt gcggtgtgtg
     9301 cggcccgccg tcgcggcggt gcgcggtgtg cccggcccgc cgtcaccgtg tgcgcggccg
     9361 ttgccgtcct cagccctggg aggccgccgc ctcccggagc gcggcgagca ccgggcggaa
     9421 gagcgggtgc tcctcggcgc cacggcgtac ggcggcgaag acccggcggg tgggggccac
     9481 atcgtccacg gggcggacca ccaccccggt gaggtccacg tcccgcagcg ccgagcgggg
     9541 gacgagcgcc acgcccgccg cggccgaggc gagcgcgacg acggcgcgga agtcgtcgga
     9601 cgagtgctcc agacgtggct ggaagccggc gtactcgcag gccaggacca ccacgtcatg
     9661 gcaggggttg ccggggtagg ggccgatcca ggggtcctgg gcgagatcgg ccaaggccac
     9721 ctgggcggcc tcggcgaggc ggtggccggg cggcaggacc gcgtcgaacg gctcggcgta
     9781 gagcgggacc cgggtcagcc gtgggtcgtc ggcgcccggt gcgccccggt attcgacggc
     9841 caccgccaca tcgacctgcc ggtcgaggac catgagcagg ctggcgtcgc cctcggcgtc
     9901 ctggacgtgg acccggatgc cgggggcggt gcgggcgagt gcggtgaggg cgggcgcgac
     9961 gaccaggccg atgccggtcg cgaaggccgc gacggtgacc gtgcccgcct cgcccgagcc
    10021 ataggcggcg agctcggact cggcgcgctc cagctgcgcc aggacggcgt tggcgtggat
    10081 gagcaggatg tcgcccgcgg cggtcagccg tacgccgcgg gcgctgcgct ccaccagacg
    10141 gtggccggtc tcctgttcca gggcggccag ctgctgggag accgccgagg gcgtgagata
    10201 gagcgcggcg gccgcggcgg tgaccgtg
//
