LOCUS       NZ_CP068988            21935 bp    DNA     circular CON 16-APR-2024
DEFINITION  Bacillus paralicheniformis strain SUBG0010 chromosome, complete
            genome.
ACCESSION   NZ_CP068988
VERSION     NZ_CP068988.1
KEYWORDS    RefSeq.
SOURCE      Bacillus paralicheniformis
  ORGANISM  Bacillus paralicheniformis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4317835)
  AUTHORS   Bhatt,H.D., Bhatt,P.P., Patel,J.H. and Thaker,V.S.
  TITLE     Characterization of Bacillus species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4317835)
  AUTHORS   Bhatt,H.D., Bhatt,P.P., Patel,J.H. and Thaker,V.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JAN-2021) Department of Biosciences, Saurashtra
            University, University Road, Rajkot, Gujarat 360005, India
REFERENCE   3  (bases 1 to 4317835)
  AUTHORS   Bhatt,H.D., Patel,J.H. and Thaker,V.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2018) Biosciences, Saurashtra University,
            Kalawadroad, Rajkot, Guajarat 360 005, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUN-2019
            Assembly Method                   :: CLC NGS Cell v. 11.0
            Assembly Name                     :: PMBP_Rhizobaci_2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: NZ_CP023665
            Genome Coverage                   :: 75.0x
            Sequencing Technology             :: IonTorrent
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003171815.2-RS_2024_04_16
            Annotation Date                   :: 04/16/2024 07:39:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,350
            CDSs (total)                      :: 4,240
            Genes (coding)                    :: 4,181
            CDSs (with protein)               :: 4,181
            Genes (RNA)                       :: 110
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 30 of 59
            Pseudo Genes (incomplete)         :: 44 of 59
            Pseudo Genes (internal stop)      :: 10 of 59
            Pseudo Genes (multiple problems)  :: 20 of 59
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:25:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1104102
            Orig. end                         :: 1126037
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP068988.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21935
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="3"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..21935
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21935
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11935](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11935)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    180..193
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     18.25"
                     /tool="antismash"
     gene            complement(280..636)
                     /gene="crcB"
                     /locus_tag="DI291_RS05535"
                     /old_locus_tag="DI291_05725"
     CDS             complement(280..636)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:1903425 - fluoride transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:1903424 - fluoride transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crcB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180153.1"
                     /locus_tag="DI291_RS05535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05725"
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="WP_026579979.1"
                     /transl_table=11
                     /translation="MMAVGFMIAGGFGSVLRFWLGNMLMAMFPRPRIPVSVMVVNIVGS
                     FALGIFVSLGIDNQTVSIVVGTGFFGGFTTFSTFSVEAVQLLAAKRVKDSAVYMLLTMA
                     CSLGGFWAGSMLIL"
     gene            complement(633..1034)
                     /locus_tag="DI291_RS05540"
                     /old_locus_tag="DI291_05730"
     CDS             complement(633..1034)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009328971.1"
                     /locus_tag="DI291_RS05540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05730"
                     /product="CrcB family protein"
                     /protein_id="WP_023856526.1"
                     /transl_table=11
                     /translation="MKSSVAVFIGGALGSLLRYFVNLHGGTAGFPWPTFIENASGSLLL
                     GLLTGFFAARAKKPLVQLCLGTGFCGGYTTMSAFSKETVFLLQSAAPHIGVLYLIVSLA
                     CGVCSAFLGIMIGKRMSGASGKEKERYQS"
     gene            complement(1050..1754)
                     /locus_tag="DI291_RS05545"
                     /old_locus_tag="DI291_05735"
     CDS             complement(1050..1754)
                     /GO_function="GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011197699.1"
                     /locus_tag="DI291_RS05545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05735"
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="WP_224145878.1"
                     /transl_table=11
                     /translation="MHIIAHRGASAYAPENTFAAFEKAVELGADFIELDVQLTKDGRLA
                     VIHDDKVDRTTNGTGFVREYTMNELEKLDAGSWFSPEFQGEKIPSLEAVLGKYHNETGL
                     LIEIKSSKTQPGIEKAAGQLISRFGHSMNTIVQSFDAGAMRALHHMYPSIPTAVLIRPR
                     FGMLPRARLRQIAEFARYVSLKATMVSPFLIKSIHSCDLKALAWTVNGEKTGRRLKSWK
                     IDGIITDYPDYF"
     gene            1946..2053
                     /locus_tag="DI291_RS05550"
                     /old_locus_tag="DI291_05740"
     CDS             1946..2053
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388844.1"
                     /locus_tag="DI291_RS05550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05740"
                     /product="YhdX family protein"
                     /protein_id="WP_003180159.1"
                     /transl_table=11
                     /translation="MGKGRIKVEERIKIETDAEMFKATLLDQTQSQKKK"
     gene            2236..3312
                     /locus_tag="DI291_RS05555"
                     /old_locus_tag="DI291_05745"
     CDS             2236..3312
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180161.1"
                     /locus_tag="DI291_RS05555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05745"
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="WP_039072568.1"
                     /transl_table=11
                     /translation="MFEKYMTMDFAVDIGISIGILLLFFAFRKIFTKYLFNLILKLTNK
                     TKTDFFNQVALAFEKPARWFFAILGIYLAIIYSPFFDGHMAIVHKLYRVSVILVIVSGL
                     YNLTAASSVLFDKINKRLELDMDDILAPFLSKILRFIIVALGISVIAGEFNYDVNGFVA
                     GLGLGGFAFALAAKDTVGNFFGGIVIIMEKPFTIGDWIETNIVTGSVEDISFRSTKVRT
                     AGEALVTVPNSVLANEAIMNWTKMRKRQVTFTLEIDPSTPREKVERCVERFKEMLKSHE
                     GVNPDVIMVNFDVLKDTHLSIFFNYYTNTTVWAENLDVRQDVNYRILDIMKEEQVDFVS
                     PGHSLFELKKMKDQQGDA"
     gene            3372..4091
                     /locus_tag="DI291_RS05560"
                     /old_locus_tag="DI291_05750"
     CDS             3372..4091
                     /EC_number="2.3.1.286"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003327787.1"
                     /locus_tag="DI291_RS05560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05750"
                     /product="NAD-dependent protein deacylase"
                     /protein_id="WP_231006177.1"
                     /transl_table=11
                     /translation="MIENAERITVLTGAGMSTESGIPDFRSAGGIWTEDLSRMEAMSRD
                     YYERYPKLFWPKFKELFQMKMTGTYQPNDGHLYLADLEKSGKDVKVFTQNIDGLHLKAG
                     SRHVYELHGSIQTAACPKCGARYGLDHILQEEVPRCHRVNGKGRECGFILKTDVVLFGD
                     AVQHFDTLFEVLNESDLLLVIGTSLEVAPVRFVPEEAHLIPGLKKAMINLDKTPYDHLF
                     DIVIHQKIAEFVRKLNC"
     gene            complement(4131..4625)
                     /locus_tag="DI291_RS05565"
                     /old_locus_tag="DI291_05755"
     CDS             complement(4131..4625)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180165.1"
                     /locus_tag="DI291_RS05565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05755"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_025811792.1"
                     /transl_table=11
                     /translation="MKIEELHSTAEYTNQLAELLIRVVDDGASIGFLPPLDEQLAEAYW
                     KTAVTPDSVLWIAKQNGRIAGSVQLHLCTKQNGRHRAEICKLMTDPAFRRQGVARSLME
                     KAIDRAKQEGRSLLVLDTREKDPSNLLYASLGFAEAGRIPAYAESADGSFDTSVFYYKK
                     L"
     gene            complement(4760..5671)
                     /locus_tag="DI291_RS05570"
                     /old_locus_tag="DI291_05760"
     CDS             complement(4760..5671)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180166.1"
                     /locus_tag="DI291_RS05570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05760"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_023856532.1"
                     /transl_table=11
                     /translation="MRQVSKKTAPSVAYLLTKAACFFVLCLILLYVWDLSQSSAAAEKK
                     ELTVSENSQMRHEGDSVPLKKATQGELLDHLSTKQQIEKRKQEKEKQKAAAEKKQEKLK
                     EKTVYLTFDDGPSAVSQRLLQILSEHDAKATFFMLEPNMKLHKKAVLNMKQQGHALGLH
                     GVTHDQKQFYKGANSPQLEMKQAQKTLKSITGVETHLIRTPYGSKPSLTEAQKKVLKKN
                     GFVYWDWNIDSMDWKYRSQKFVPEVMNQLNTLEKRQTKQPIVILMHDIPSTVQSLPLLL
                     TNLKNMGYSFATLDESMTPVHE"
     misc_feature    complement(5745..5763)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.88"
                     /tool="antismash"
     misc_feature    5793..5804
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.03"
                     /tool="antismash"
     misc_feature    5807..5820
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.55"
                     /tool="antismash"
     misc_feature    complement(5808..5821)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.57"
                     /tool="antismash"
     misc_feature    5856..5865
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.05"
                     /tool="antismash"
     gene            5965..6816
                     /gene="dat"
                     /locus_tag="DI291_RS05575"
                     /old_locus_tag="DI291_05765"
     CDS             5965..6816
                     /EC_number="2.6.1.21"
                     /GO_function="GO:0047810 - D-alanine:2-oxoglutarate
                     aminotransferase activity [Evidence IEA]"
                     /GO_process="GO:0019480 - L-alanine oxidation to pyruvate
                     via D-alanine [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (42-271). E-value: 3.2e-46.
                     Score: 149.9. Matches aSDomain:
                     nrpspksdomains_DI291_RS05575_Aminotran_4.1"
                     /codon_start=1
                     /gene="dat"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020450756.1"
                     /locus_tag="DI291_RS05575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05765"
                     /product="D-amino-acid transaminase"
                     /protein_id="WP_128822871.1"
                     /transl_table=11
                     /translation="MKVLFNGRLMERSECAVDIEDRGYQFGDGVYEVIRIYNGILFTLD
                     EHIARLYKSAAEIGIDLSFSEAELKSQLKELVDINQMRDGGLYLQVTRGKAPRKHQYGA
                     GLTPQVTAYTFPIQKPEKEQQNGVSAITADDMRWLRCDIKSLNLLYNVMIKQKAHEASS
                     FEAILIRDGLVTEGTSSNVYVVKKNVIYTHPVTTLILNGITRMKVLQLCEQHGLNYEEK
                     AVTKDELLNADEVFITSTTAEVIPVTSIDGQTIGSGAPGPLTKNVQTALQNSILSETAK
                     PV"
     aSDomain        6091..6777
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DI291_RS05575_Aminotran_4.1"
                     /evalue="3.20E-46"
                     /label="DI291_RS05575_Aminotran_4.1"
                     /locus_tag="DI291_RS05575"
                     /protein_end="271"
                     /protein_start="42"
                     /score="149.9"
                     /tool="antismash"
                     /translation="TLDEHIARLYKSAAEIGIDLSFSEAELKSQLKELVDINQMRDGGL
                     YLQVTRGKAPRKHQYGAGLTPQVTAYTFPIQKPEKEQQNGVSAITADDMRWLRCDIKSL
                     NLLYNVMIKQKAHEASSFEAILIRDGLVTEGTSSNVYVVKKNVIYTHPVTTLILNGITR
                     MKVLQLCEQHGLNYEEKAVTKDELLNADEVFITSTTAEVIPVTSIDGQTIGSGAPGPLT
                     KNVQTAL"
     gene            complement(6856..8214)
                     /gene="nhaC"
                     /locus_tag="DI291_RS05580"
                     /old_locus_tag="DI291_05770"
     CDS             complement(6856..8214)
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nhaC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009328967.1"
                     /locus_tag="DI291_RS05580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05770"
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="WP_023856534.1"
                     /transl_table=11
                     /translation="MSNEKRLSFSISALLFLAILFIIFTCLFIFKAEAHIPLLICVGFL
                     AAVGAVKGHSWKDLESGIVSGIRNGVQPIIVLCLIGILIGVWEYSGAIPTVTVYALNLI
                     EPQHLLLTALFSCLVISSLVGSSFTTVSTIGVALIGVAAAAGVPLTWAAGAVICGACFG
                     DKMSPMSDTTNFAAGVGELPIFKHIRHMAGTTIPALLITILLFFFMGRSLTAAPASTEN
                     IQAIINGIESTVNISVWALLSPLLVIVLAVRRTPVIPSLAAGIVSAGILAALIQPDASI
                     SSFLSAMQNGPVFSADTEAVEKILNRGGLQSMMGSVSLIIIAFALGGLMEKIGLITSLL
                     EGVIKGIHTKGRLVFSTVSSSIGMNLATGEQYLSILIPGQSFKKLYDKLGIDRKHLSRS
                     LEDGGTLINPMIPWGVSGAFMSSALGVPVIEYLPFVFFLYLSPLFSILFGFRK"
     gene            8451..9431
                     /locus_tag="DI291_RS05585"
                     /old_locus_tag="DI291_05775"
     CDS             8451..9431
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009328966.1"
                     /locus_tag="DI291_RS05585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05775"
                     /product="aldose 1-epimerase"
                     /protein_id="WP_026579975.1"
                     /transl_table=11
                     /translation="MSYTVQKSRFLDEEAIWLENDDLEAVLVPGWGSNLISLKWKPSGL
                     KLLKTPETKEEYNANPFLFGIPVLFPPNRIDHGRFTYAGRTYELPINEKPLENHLHGFL
                     YDKKWTVEKVEATEEMIIVQTKLDSDDHPDIKAIFPHSFSITITYTLEGQHLKIDASAV
                     NRGQDPMPIGLGYHTSFRYPLNEAGDKERCLFTLPASKRWTLTDRMLPTGEYRVTEEFK
                     AGKMAAGERLDDILAAEQDQEGNSAAVIADSLAGIRVRYQCDGHFKHWVVFNGTSDQDD
                     LLCIEPYTWMTNAPNLNLPKDVTGFRDLGPQEELTMRSKIEVGGI"
     gene            complement(9447..9923)
                     /locus_tag="DI291_RS05590"
                     /old_locus_tag="DI291_05780"
     CDS             complement(9447..9923)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180175.1"
                     /locus_tag="DI291_RS05590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05780"
                     /product="DUF4944 domain-containing protein"
                     /protein_id="WP_023856536.1"
                     /transl_table=11
                     /translation="MKQEYKRPLLFIASLFTAFCTVYFGGRLIGFYMTEYPKWNGQSAD
                     GNWEAVIKKIEGRTLFGGDLYWTGDRGELDDIYLEKLVVKFGDEIVLNSQVETPMKDYA
                     GGEFPGGGSKEQSVSFLEELEEAEFAGRKITVQLDWREGKQASHTAFTLDKSSW"
     gene            complement(10001..11935)
                     /locus_tag="DI291_RS05595"
                     /old_locus_tag="DI291_05785"
     CDS             complement(10001..11935)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03882"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180177.1"
                     /locus_tag="DI291_RS05595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05785"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_128822868.1"
                     /sec_met_domain="TIGR03882 (E-value: 3.3e-48, bitscore:
                     161.9, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 6.3e-134, bitscore:
                     444.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 2e-84, bitscore: 282.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRCILVIGEGLMAEDASQQLSAEYNIIRRSDFENSIPEETAFAL
                     VLHDAWRPLLYREAEKVLRAAGIPWLRGFASFGEGVIGPLVNPSASGCSQCADMRRYIS
                     GPDSRETLELEQKSNGISRDPWVSKTGCRQMVSLICTEVDNIMNGGCGRLKKNLYIVNL
                     KTLESSLHAFIPEPTCPICGSLPEDGAESARISLRPSLKTNPDSFRVRNTDDLKQTLAK
                     DYLDHRTGIFNTKIYDAILPFADMIVNMPLWTGNEGVGGRSHSYEDSELTAILEGLERY
                     SGIEPRGKRTVVHDTYENVKDRALNPAKVGLHQAEQYMHPDFPFQPFHPARPLRWVWGY
                     SFLQKRPILIPESLAYYSLGREDSFVYETSNGCALGGSLEEAIFHAILEAAERDSFLLA
                     WYARLPLRQLDLGSSEDPELRLMTERVRSVAGYDLHVFNSTMEYGIPSVWAIAKNRKRE
                     GLNLICSAGAHPDPVKAVKSALHELAGMMLKHDRKFESERSKYHQMLRNPALVQEMEDH
                     SFMYGLPEAEERLRFLLNQSRPLQTFDDAFKKRKKHLDLTEDLCDLLEAFRSLNLEVIV
                     VDQTSPVIKRNGLYCVKVLIPGLIPMTFGQRFIRLEGLERIFTVPKELGFAEEPLTPEQ
                     LNLHPHPFP"
     gene            complement(11935..13782)
                     /locus_tag="DI291_RS05600"
                     /old_locus_tag="DI291_05790"
     CDS             complement(11935..13782)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006636651.1"
                     /locus_tag="DI291_RS05600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05790"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_205802212.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1112.1,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     6.4e-52, bitscore: 171.5, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 3.1e-13,
                     bitscore: 47.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHLTASARLKVNQDTWFLPDPNGGAYFRNNSGSFRIKGSSIAQW
                     IEKLLPMFNGEHSLEDLTKGLQAPYRKRVYEIGEMLYKNGFVRDVSRDHPHKLESSVLQ
                     TFEAQIEFIESFADSGAYRFQLSRQTKILAIGAGSFLTKLVRSLIDSGFSRIRAIVTDA
                     SGHALDELGEISGQTESGLEIGCAETQHWREAVRSADWVLYVSDRGFTDELRDLQTFCL
                     EENKGFIPGICLKQVGLAGPVFHQQGDGCLKDAWRRLHRSALHEERTLRTFPSAGKDML
                     ANVIVFELMKATAEIAPLSKKNQVYLIDLATLEGGWHMFLPHPDFACGKDSPELICDLE
                     AKLSERPGREAESRLFQCFSELTSPVTGIFHLWEEKHLRQLPLAQCFVQTADPLSSGPA
                     ELLPKTVSVGLTHQEARREAGLAGIEMYASRLNRSYPSNGEIAAGETLAEGVLRGLEKC
                     LEHRLRERIKSGKETISLVQLGGMEDRHTAFYLKALTVLYGKPEIGLGKNIQGFPVAWA
                     GIRGRWYGSSGLNITFALRKALERALTDKDPVKGADVLLESSDLKLATPVSADLQQTLL
                     SALKNNCGLQLYVYELPAEPFFKEKLAGIYCVQLRKEES"
     aSDomain        complement(13483..13782)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DI291_RS05600_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="4.30E-54"
                     /identifier="RREFam011.1"
                     /label="DI291_RS05600"
                     /locus_tag="DI291_RS05600"
                     /protein_end="100"
                     /protein_start="0"
                     /score="171.5"
                     /tool="antismash"
                     /translation="MTHLTASARLKVNQDTWFLPDPNGGAYFRNNSGSFRIKGSSIAQW
                     IEKLLPMFNGEHSLEDLTKGLQAPYRKRVYEIGEMLYKNGFVRDVSRDHPHKLES"
     aSDomain        complement(13516..13761)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DI291_RS05600_Thiopeptide_F_RRE.1"
                     /evalue="2.10E-15"
                     /identifier="RREFam004.1"
                     /label="DI291_RS05600"
                     /locus_tag="DI291_RS05600"
                     /protein_end="89"
                     /protein_start="7"
                     /score="47.5"
                     /tool="antismash"
                     /translation="ARLKVNQDTWFLPDPNGGAYFRNNSGSFRIKGSSIAQWIEKLLPM
                     FNGEHSLEDLTKGLQAPYRKRVYEIGEMLYKNGFVRD"
     misc_feature    13891..13904
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.97"
                     /tool="antismash"
     misc_feature    complement(13892..13905)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.02"
                     /tool="antismash"
     misc_feature    13893..13906
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(13896..13912)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.69"
                     /tool="antismash"
     misc_feature    14341..14358
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.69"
                     /tool="antismash"
     gene            complement(14889..15389)
                     /locus_tag="DI291_RS05610"
                     /old_locus_tag="DI291_05800"
     CDS             complement(14889..15389)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017695384.1"
                     /locus_tag="DI291_RS05610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05800"
                     /product="universal stress protein"
                     /protein_id="WP_039072577.1"
                     /transl_table=11
                     /translation="MFKADRIIVAFDGKEESKKALKKAIDLSKRLGSQLTVSHVHEPRQ
                     VRTEAATERPAAGAPYLYSGFPAAPRVPHDSDLAGEPMIYEDSAEEAIAAAKIILSENQ
                     YDAEIEVLEGDPANAVLQHAENIGADLVITGTRDQNRLKKLLFGSVSDKISTKSEIPVL
                     IVK"
     misc_feature    15707..15720
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.15"
                     /tool="antismash"
     misc_feature    complement(15838..15852)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.4"
                     /tool="antismash"
     gene            15911..17665
                     /locus_tag="DI291_RS05615"
                     /old_locus_tag="DI291_05805"
     CDS             15911..17665
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388852.1"
                     /locus_tag="DI291_RS05615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05805"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_079289317.1"
                     /transl_table=11
                     /translation="MFSVLWKLGWFFKASWRRYTIAVVLLIIVNVLEMFPPKLLGNAID
                     DMQAGTFSKAGMLGYIGLFLALGAVVYILSYYWMYQLFGGANLVEKILRSKLMGHLLKM
                     TPSFYEKNRTGDLMARATNDLKAISMTAGFGILTLVDSTMYMLTILLTMGFLISWKLTL
                     ASIIPLPLMAAAISIYGKKIHERFTEAQDAFGALNDRVLESVSGVRVIRAYVQEKNDVS
                     RFNSMTADVYKKNMKVALIDSLFEPTVKFLVGISYLIGLGYGAYLVFRSQLTLGELVSF
                     NVYLGMLIWPMFAIGELINVMQRGNASLDRVNETLAYEPDVREPAEPEAAEPGDIVFDG
                     VAFTYPSSASENLADISFTVLEGQTVGVVGKTGSGKTTLVKQLLRQYPKGKGTITISGV
                     PIDRLPLDQLRSWIGYVPQDHVLFSKSVKDNILFGGRLAEERDLYDVISAAHLKKDIEM
                     LSDGLETMVGEKGVALSGGQKQRISIARAMIAEPHILILDDSLSAVDAKTEAAIIENIR
                     SRRKGKTTFITSHRMSAVEHADFILVMENGRIVERGTHQELISRKGWYFEQYEAQQLPS
                     GEEGGTVA"
     gene            17662..19680
                     /locus_tag="DI291_RS05620"
                     /old_locus_tag="DI291_05810"
     CDS             17662..19680
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180189.1"
                     /locus_tag="DI291_RS05620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05810"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_101560657.1"
                     /transl_table=11
                     /translation="MTTGKRLFQYALLYKKILIWALVMLTIAVTAELTGPMIAKKMIDD
                     HILGIEKTWYETTEETKYTVSYKGKEYIREDRTDSSAEKLQEVHIFQVGMNYYFVEEPV
                     SFDGERTVSGEELRMTSGDRTETYKADRLSLSEVYAFYEPEIGGLISLVSIYFGLLVFS
                     IFFHYGQFYLLQMSANRIIQKMRQDVFANIQRLPIRYFDNLPAGKIVARVTNDTEAIRD
                     LYVTVLSTFVTNIIYMAGIFAALFFLDVRLAGVCLLILPLIVIWAAVYRKFASGYNHKL
                     RSINSEINAKMNESIQGMPIIQAFRRGQDTKEEFEQLNESHFHYQNKMLKLNSLMSHNL
                     VNILRNVMFTALIWYFGGAALNAEGMISIGVLYAFVDYLNRLFQPITGIVNQFAKLELA
                     RVSSERVFRLLDEPGVDVKEPGSERARGRVVFEDVSFRYHDGEDVLKNISFEAQQGETV
                     ALVGHTGSGKSSILNVLFRFYDIEKGDVKIDGRSIYDMSRQEIRKQMGIVLQDPYLFSG
                     TIASNVSLDNADLTRDQIEAALKQVGALEMLARLPKGLDEPVIEKGSTLSSGERQLISF
                     ARALAYDPAILILDEATAHIDTETEAVIQKALDVVKQGRTTFIIAHRLSTIKNADQILV
                     LEKGRIIERGNHEELMKQKGQYYQMYELQKGKGTLTG"
     gene            complement(19700..20326)
                     /locus_tag="DI291_RS05625"
                     /old_locus_tag="DI291_05815"
     CDS             complement(19700..20326)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009328963.1"
                     /locus_tag="DI291_RS05625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05815"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_243456945.1"
                     /transl_table=11
                     /translation="MLKIALFGGTGRVGQAFLNFVEEDGRYSVYALVRRTEGARIPDKC
                     CQALTGNARNQHDVESLIKDSDIVVSCLNTDGDDTLTVSIEHMINAMNAHRIKRLITIG
                     TAGILNARQNQDLYRFETNESKRRSARAAQEHARVYERLRESELDWTIVCPTYLPDGPA
                     LKTYRFEQDVLPDGGKEISTGDTAHFLFKQLESDQFVKARVGLAY"
     gene            complement(20347..20490)
                     /locus_tag="DI291_RS05630"
     CDS             complement(20347..20490)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180193.1"
                     /locus_tag="DI291_RS05630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_023856545.1"
                     /transl_table=11
                     /translation="MQLMLSINWELIQFVGISLLNEYVSNVHPYHGTFCFRGAFSSGRS
                     DV"
     misc_feature    complement(20659..20674)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
     gene            complement(20661..20864)
                     /locus_tag="DI291_RS05635"
                     /old_locus_tag="DI291_05820"
     CDS             complement(20661..20864)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390835.1"
                     /locus_tag="DI291_RS05635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05820"
                     /product="alpha/beta-type small acid-soluble spore protein"
                     /protein_id="WP_020450770.1"
                     /transl_table=11
                     /translation="MANQNSSNQLVVPGAAQAIEQMKFEIASEFGVNLGADTTSRANGS
                     VGGEITKRLVSQAQASMGGQQF"
     gene            21098..21322
                     /locus_tag="DI291_RS05640"
                     /old_locus_tag="DI291_05825"
     CDS             21098..21322
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180197.1"
                     /locus_tag="DI291_RS05640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DI291_05825"
                     /product="hypothetical protein"
                     /protein_id="WP_020450771.1"
                     /transl_table=11
                     /translation="MMCPVCNGILVQTRHCPKCGGEMADAGRATDFFGPYSPYMEFDSF
                     KQTQTVCVHLYTCQDCTYEETVEIETTEA"
ORIGIN
        1 aaaagacgat gttttgaacg ttatttctgc gaattgggac agctttcaaa cagcggccat
       61 tgaaaaagga taaaaaggga agaatccatt ttgaagcatt caaaatggat tctttaatgt
      121 gtttgtatct tttttagttg tccgtggtgt tcctttctga acaatgccat tcaaatcagg
      181 gcacagcttt tgcgacggcg ggcgcaagaa aaatgacaac cggaagtaca tgtgcaagcg
      241 cctgttcata gccgaacgag catcattgtt tcatcatctt cacaaaatca gcatgctgcc
      301 ggcccagaac cccccgagtg agcatgccat tgtaagcagc atgtaaaccg ctgaatcctt
      361 tacacgtttt gcagccaaaa gctgaaccgc ttcgacactg aatgtggaaa atgttgtgaa
      421 ccctccgaaa aatccagttc cgaccacgat tgagaccgtt tgattgtcaa tgccgaggct
      481 gacgaatatg ccgagggcga atgagccgac aatattgacc accatcacgc tgacaggaat
      541 gcgcgggcgc ggaaacatcg ccatgagcat attgccgagc caaaatctta aaacggagcc
      601 gaatcctccg gcgatcataa atccaactgc catcatgatt gataccgctc cttttctttc
      661 cctgacgctc cgctcatcct tttgccgatc atgatgccca aaaatgcgga gcacaccccg
      721 caggcaagcg acacgatcaa gtacagaacc ccgatgtgcg gagcggccga ttgcagcaaa
      781 aatacggtct ctttagaaaa agcggacatt gtcgtatatc ctccgcaaaa ccccgttcct
      841 aaacataact ggacgagcgg cttttttgcc cgagccgcaa aaaaacctgt caaaaggccg
      901 aggagaaggc ttccagacgc attttcaata aaagtcggcc aaggaaaacc ggcggtgccg
      961 ccatgcagat tgacgaagta gcgcagcagc gagccgaggg ctcctccgat aaaaacggca
     1021 acagatgatt tcatactctt ccttctttct caaaaataat ccgggtagtc ggtaatgatc
     1081 ccgtcgattt tccagctttt caggcggcgt cccgttttct ccccgttgac cgtccaggcc
     1141 agcgccttca aatcacagct gtgaatcgat ttgatcagaa aagggctgac catcgtagct
     1201 ttcaggctga cgtaccgggc aaactccgcg atttgccgca gccgggcgcg cggcagcatt
     1261 ccgaatcgcg gcctgatcaa aacggcggtc ggaatcgaag gatacatgtg atgaagcgcc
     1321 ctcatggcgc ctgcgtcaaa cgactggaca atcgtgttca tcgaatggcc gaaccggctg
     1381 atcagttgtc cggccgcttt ttcgattccg ggctgggttt tggacgactt gatttcgatg
     1441 agaaggcccg tctcgttgtg atatttcccc agaacagctt caagtgaagg gattttttcg
     1501 ccctgaaatt ccgggctgaa ccagcttccc gcatcaagct tttcgagctc attcatcgta
     1561 tactcgcgaa cgaacccggt accgttcgtc gttctgtcaa ctttgtcatc gtggatgacg
     1621 gcaagtctgc cgtcttttgt cagctgtaca tcgagttcga taaaatcagc cccgagctcc
     1681 accgcttttt caaaagcggc aaacgtattt tcaggggcgt aagccgaggc tccgcgatgt
     1741 gcgataatat gcaagcatgt cagctcctct tgataaaatc tttccatcac aaggataccc
     1801 gattttggcg atgcaagtaa atcatttgac tgaagcggac aaagggcagg gagaagagac
     1861 aagcgacaaa tttcggcaaa atggtacaaa aggatcattt actaaggatt ctgatatttt
     1921 ataatggaca aaaggaggcg agatgatggg taaagggaga attaaagtgg aagaacggat
     1981 taagatcgaa accgatgctg aaatgtttaa agcgactctc cttgatcaaa cacagtctca
     2041 gaagaagaaa tagcggtgtt ggcccgaatc acgttgtctc tggaacaata aaatatgatg
     2101 atcatcaggc tgccgaagtg ttcggcagcc ttttatgcgt gtcgacggtt atttttggtg
     2161 cacaataaag tgagaaattt ttttctcgtt ttagtataat taaagcttga tgagtgaaat
     2221 aagggagaga aagcaatgtt cgaaaagtat atgacaatgg atttcgctgt cgatatcgga
     2281 atcagcatcg gtatccttct tttatttttc gcgtttcgaa aaatatttac gaagtacttg
     2341 ttcaacttaa tactgaaatt gacgaataag acgaaaacag acttttttaa tcaggtggcg
     2401 ctggcgtttg aaaagccggc ccggtggttt tttgcgatac tcggtattta tctggccatc
     2461 atatattccc cgttttttga tgggcatatg gcgatcgttc ataaactgta cagagtgtcc
     2521 gtgattttgg ttattgtaag cggcctatac aacttaacgg cggcttcgtc ggttttattc
     2581 gataaaatca ataagcggct tgagcttgat atggatgata ttcttgcgcc gtttttgtcc
     2641 aagattctcc gctttatcat tgtagcgctc ggaatcagcg ttatcgccgg agagttcaat
     2701 tatgatgtca acggatttgt tgccggactc gggctcggcg gcttcgcttt tgctcttgcg
     2761 gcaaaagaca ctgtcggcaa ctttttcggc ggaattgtca ttattatgga gaagcccttt
     2821 acaatcggcg attggattga aacaaatatc gtcaccggat ctgttgaaga tatatcgttc
     2881 agaagcacga aagtccgcac ggctggagaa gctctcgtga ccgtccccaa ctcggtgctg
     2941 gctaacgaag caatcatgaa ctggacgaaa atgcgaaagc gtcaggtcac ctttacgctc
     3001 gaaatcgatc cgtccacccc gcgcgagaaa gtcgaacgat gtgtggagcg tttcaaagaa
     3061 atgctcaagt cgcacgaagg ggtcaacccg gatgtcatta tggtcaattt cgacgtcctg
     3121 aaggatacgc atttaagcat cttcttcaac tactatacca atacgacggt ctgggccgaa
     3181 aacttggacg tcagacagga tgtcaactac cgcattcttg atattatgaa agaggagcag
     3241 gttgattttg tttctccggg tcacagcctc tttgagttga agaaaatgaa agatcagcaa
     3301 ggagatgctt aggtaacgct tttggaaggg agacaagcca aatggaggaa aaagccctga
     3361 gatttgtgga gatgatcgaa aatgccgagc gcattaccgt tttgacaggc gccggtatga
     3421 gcacggaatc aggtattccc gattttcgtt cagccggcgg catatggacg gaagatctgt
     3481 cgagaatgga agcgatgagt cgtgattatt acgaacgata tccaaaattg ttttggccga
     3541 agtttaaaga gctttttcaa atgaaaatga ccggaactta tcagccgaat gacgggcacc
     3601 tttatttagc cgatctcgag aaaagcggta aggatgtcaa ggtgttcacg caaaatatcg
     3661 acggactgca tcttaaagcg ggaagccggc atgtatatga actgcacggt tcgatccaaa
     3721 cagccgcatg cccaaaatgc ggggcgcgct atggtcttga ccacattctt caagaagaag
     3781 tgccaagatg ccatcgcgtc aatggcaagg ggagagaatg cggattcata ttaaaaacgg
     3841 atgttgtgct gttcggcgat gccgttcagc attttgacac gctttttgaa gtcctcaacg
     3901 aatccgacct gcttttggtg atcggcactt cacttgaagt ggcgcctgtc aggtttgttc
     3961 ctgaagaagc gcacttgatc ccaggcttga agaaagcgat gatcaatctc gataagacac
     4021 cttacgatca tttatttgat attgtcatcc atcaaaaaat cgccgagttt gttcggaagc
     4081 ttaactgtta aaaaggcgct ccagaccgga gcgccttttt ctgagcttca tcacaatttt
     4141 ttataataaa aaacggatgt atcgaagctg ccgtctgcag attccgcgta tgcgggaatg
     4201 cggccggctt cggcaaagcc gagcgaagcg taaagaaggt tggacgggtc tttttccctt
     4261 gtatccagca cgagaagaga tctgccttcc tgtttcgccc tgtcgatcgc tttttccatt
     4321 aacgatctgg cgacgccctg ccgcctgaag gcgggatctg tcattaactt gcagatttcc
     4381 gctctgtggc ggccgttttg ttttgtgcat aagtgcaatt gaacacttcc tgcgatccgg
     4441 ccgttttgtt tggcaatcca tagcaccgaa tccggtgtga cggctgtttt ccaataagcc
     4501 tccgccagct gctcatcaag cgggggcaga aagccgatcg atgccccgtc atcgacgacc
     4561 cggatgagaa gctcggccaa ttgattggta tattcggcag tcgaatgcag ctcttcaatt
     4621 ttcatttatt caccccatga tataaagata actgcatcat aatcagaaaa cggtttgttt
     4681 ggcaacaagt gtgtcagata atcacacttg cgggaggaaa taaaaaaatc cccttcagca
     4741 ggggatcagg catggggggt tattcatgaa cgggtgtcat cgattcatca agcgttgcaa
     4801 atgaataccc catgtttttt aaatttgtca gcaataacgg caacgattga accgttgaag
     4861 gaatatcgtg catcaggatc acgatcggct gttttgtctg ccgcttttcc agcgtattca
     4921 gctggttcat gacttccgga acgaattttt ggcttctgta tttccagtcc atgctgtcaa
     4981 tattccagtc ccaataaaca aatccgttct ttttcagcac ttttttctgc gcttcggtca
     5041 gcgaaggttt gctcccgtaa ggtgttctga ttaaatgggt ttcaaccccg gtgatagact
     5101 tcagcgtttt ttgagcctgc ttcatttcca gctgaggaga attggcgcct ttataaaatt
     5161 gcttttggtc atgggtcact ccgtgaagtc caagtgcatg gccctgctgc ttcatattga
     5221 gaacggcttt tttgtgaagc ttcatgttcg gttcgagcat gaagaacgtc gctttagcgt
     5281 catgttcgga taaaatttgc agcagccttt ggcttacggc tgaaggccca tcgtcaaacg
     5341 tcaaataaac cgttttttcc ttcaattttt cttgcttttt ttcggcggca gctttttgct
     5401 tctctttttc ctgcttgcgc ttttcgatct gctgttttgt gctcaagtga tcgagaagtt
     5461 cgccttgcgt tgcttttttg agcggaacgc tgtctccttc atgcctcatt tggctgtttt
     5521 ccgacaccgt aagctctttt ttctcagcgg cggcagagga ctgtgaaagg tcccacacgt
     5581 acaggagaat cagacacaaa acaaaaaagc acgctgcttt cgtcaacaga taagctacag
     5641 atggggcagt tttttttgat acttggcgca tgtcactctc tccgtatcat ttttctcgtt
     5701 ccaatgccat tatagaatgc tagtctcata aaataatgga tcacaatgtt taagtataca
     5761 ggattggaaa gaagatgaat acaggatgaa gggaaaaaga tatcaaattt taatagaaaa
     5821 tgctgaacga tggggaatgc tgtttttttg atcatgaagg cggagaaaag tttttggaaa
     5881 tattgcacta ttttgaaggg cagggtcgtg ttagaatgga atggagaaaa ttcagaagtc
     5941 aacaaaaaac aaggggatgg agaaatgaaa gttcttttta acggccggct gatggaacgg
     6001 agcgagtgtg cggttgatat tgaagacaga ggctaccaat ttggagacgg cgtctatgaa
     6061 gtcatccgca tttacaatgg aatcttgttc acgcttgatg aacacattgc ccgcttatat
     6121 aaaagcgcag ccgaaatcgg aatcgacttg tctttttcag aagccgagct gaaaagccag
     6181 ctaaaagagc tcgtcgacat caatcaaatg cgggacggcg ggctgtatct tcaagtgaca
     6241 aggggaaaag ccccgagaaa gcaccaatac ggagcagggc ttacgcctca ggtgacggct
     6301 tatacatttc ctattcaaaa gcctgaaaaa gaacagcaaa acggcgtttc agctattact
     6361 gcggacgaca tgcgctggct gagatgcgac attaagagtt taaatctgtt gtacaatgta
     6421 atgatcaagc aaaaagcgca tgaagcttct tcattcgaag cgatcttaat tcgcgacggg
     6481 ttggtgacgg aagggacgtc ctcaaatgtt tacgtcgtca agaaaaacgt tatctacacc
     6541 catcctgtga caacgctcat cttaaacggc atcacgcgga tgaaagtgct tcagctgtgt
     6601 gagcaacacg gcttgaacta tgaagaaaaa gcggtgacaa aggatgaatt gctgaatgca
     6661 gatgaggtgt tcatcacgtc aacgacagcc gaagtcattc cggtcacatc gattgatggg
     6721 caaactatcg gctccggagc gcccggaccg ctcaccaaaa atgtgcagac cgcattgcaa
     6781 aacagcattt tgtcagagac agccaaaccg gtttaacaaa agaaaaacgc gcttccaagg
     6841 ggaaacggcg tttttttact tgcggaaacc gaacaaaatt gaaaagagcg gcgataaata
     6901 taggaaaaac acaaacggca aatattcaat aacgggaacg ccgagcgcgc tggacatgaa
     6961 cgcgccgctg actccccaag gaatcatcgg attgattaat gtccctccgt cttcaagcga
     7021 tctcgacaaa tgttttcggt cgattccgag cttgtcatac agctttttaa aggactgtcc
     7081 gggaatcaag atcgataaat actgttcgcc tgtcgccagg ttcatgccga tgcttgatga
     7141 aacggttgag aacacaagcc ggcctttcgt atgaatgccc ttgatcacac cttcaagcag
     7201 gcttgtaatc aggccgatct tttccatgag accgccgagc gcgaatgcga tgataatcag
     7261 ggaaacagag cccatcatcg attgaaggcc gccgcggttt aaaattttct caacggcttc
     7321 agtgtcggct gagaaaacag gaccattctg catcgctgac aaaaacgatg aaatgctggc
     7381 gtcaggctgt atcaacgcgg caagaattcc ggcggaaacg atccccgctg caagcgatgg
     7441 aatgacgggc gttcgtctga cagcaagtac aatcacaaga agaggcgaca gaagcgccca
     7501 gacgctgatg ttgactgtac tttctattcc gtttatgatc gcttgaatgt tttcggtaga
     7561 agccggtgcc gccgttaaag aacggcccat gaaaaagaaa agcaaaatcg tgatcaaaag
     7621 agcggggatc gtcgttcccg ccatatgtct aatatgcttg aaaatgggaa gctctccgac
     7681 tcctgcggca aaattagtcg tgtcagacat cggagacatt ttgtcgccga aacaggcgcc
     7741 gcaaatcaca gctcccgccg cccatgtcag tggaacgccg gccgctgcgg ccacgccgat
     7801 gagggcgacg ccgatcgtgc tgaccgtcgt aaagctggag ccgaccaatg aactgatcac
     7861 aagacagctg aaaagtgcgg tgagcagcag gtgctgcggt tcaatcagat tcaacgcgta
     7921 aaccgttacc gtcggaatcg cgccgctgta ctcccagact ccgattaaga tgccgattaa
     7981 acaaaggacg ataatcggct gaacgccatt ccggatgcct gagacaatgc cgctttcaag
     8041 gtctttccag gaatggcctt tcaccgcgcc gaccgcagct aaaaaaccaa cgcaaatcaa
     8101 cagcggtatg tgcgcttctg ctttaaatat gaataagcag gtgaaaataa tgaacaatat
     8161 ggctaaaaac aatagagccg atatggaaaa cgatagacgt ttttcgtttg acaagtcaca
     8221 cacctcatta gaagaaatat ctctctttaa tactttgatg cttttgtgca taaacgtatt
     8281 ataacagaaa aatagattat atacttaaat taaaatattt caaacatttt tcaaaggttc
     8341 acccattctc ttttgaaagc gctgactttt ttaagatata atagattgga gataggcatg
     8401 tactgataca cgtttcactg atcctttagc caaaataggg ggaaatgcga atgtcttaca
     8461 ctgttcagaa aagccggttt ttagatgagg aagcgatctg gttggaaaat gatgatttag
     8521 aggctgtact tgtgcccggg tggggaagca atttaatttc actgaagtgg aagccgagcg
     8581 gtttgaaatt gttgaaaacg cctgaaacaa aggaagaata taacgcgaat ccgtttttat
     8641 tcggaattcc tgttcttttt cctcccaacc ggatcgatca cggaagattt acatatgcgg
     8701 gaagaacgta cgagctgccg atcaatgaaa agccgctcga aaaccacctg cacggatttc
     8761 tttacgataa aaaatggacg gtcgaaaaag tggaggcaac agaagagatg atcatcgtgc
     8821 agacgaagct ggactctgat gatcatcccg atattaaagc gatctttccg cactcgtttt
     8881 ccatcaccat cacttacacg ttagaaggac agcatctgaa aatcgatgca tcggctgtca
     8941 atcgcggtca agacccgatg ccgatcggat tggggtacca cacatctttc cgctatcctt
     9001 taaacgaagc aggagataaa gaaaggtgtc tgtttactct tcctgcctca aagcgatgga
     9061 cgctgacaga ccgcatgctg ccgacaggcg agtatcgggt gacagaggag ttcaaagcgg
     9121 gaaaaatggc agcgggagaa aggcttgacg atatattggc agctgaacaa gaccaggaag
     9181 gaaacagcgc ggccgtcatt gcggacagcc tcgccggcat tcgcgtccgc taccaatgcg
     9241 acggtcattt taagcactgg gttgtgttta acggtacatc tgatcaggat gacctgcttt
     9301 gtatagagcc atatacttgg atgacgaatg caccgaacct caaccttccg aaggatgtga
     9361 ccggatttcg ggatttggga ccgcaggaag agcttacgat gcgaagcaaa attgaggtgg
     9421 gcggaatata atcgatattc cgccttttac catgagcttt tatcaagggt aaatgctgta
     9481 tgggacgctt gtttgccctc tctccaatcc agttgaaccg tgatcttgcg gccggcgaat
     9541 tcggcttctt caagctcttc caaaaaagaa acggattgtt cttttgaccc tccgccgggg
     9601 aattcgcctc ccgcgtaatc tttcatcggc gtctcgactt gggagttcaa aacgatttca
     9661 tcaccaaact ttacgaccaa cttttccaaa tatatatcgt ccagctcccc gcggtcgcct
     9721 gtccaataga ggtctccgcc aaatagcgtg cggccttcta tctttttgat cacggcctcc
     9781 caatttccat cggcgctttg tccgttccat ttcgggtatt ccgtcatata gaaaccgatc
     9841 agtctgccgc cgaaataaac ggtgcaaaag gccgtgaaaa gggaagcaat gaaaagaagc
     9901 ggccgcttgt attcctgttt catattatcc accgcctaaa aagttctgct ttatgatcat
     9961 aaagcagaac aatcgggaaa aaaagtcatt ctcttaaatt ttaagggaac gggtgcgggt
    10021 gcaggttcag ctgttctggt gttaacggct cttctgcaaa gccgagctcc ttcggcaccg
    10081 tgaaaattct ctcaagtcct tccaggcgga tgaagcgctg tccgaatgtc atcggaatca
    10141 ggcccgggat aagcactttc acacagtaaa ggccgttccg tttgataaca ggggaagtct
    10201 ggtcaacgac aatcacttca agattgagac tccggaaagc ttcaagcagg tcgcagagat
    10261 cttcggttaa atcaaggtgt ttctttcttt ttttaaaggc atcgtcgaat gtttgtagag
    10321 gccggctttg attcagcaaa aaccggagtc gctcttcagc ttcaggcagt ccgtacatga
    10381 agctgtgatc ctccatttcc tgcactaaag caggattgcg gagcatctgg tgatatttgc
    10441 tcctttcaga ttcaaatttg cggtcgtgct tcaacatcat gcctgccagc tcatgaaggg
    10501 cgcttttcac cgcttttacg ggatcggggt gggcccctgc ggaacaaatc agatttaatc
    10561 cttcccgttt tctgtttttg gcgatcgccc aaacgcttgg aatgccgtat tccatcgttg
    10621 aattaaagac atgcagatca tatcccgcca cacttcgcac cctctctgtc atgaggcgta
    10681 attccggatc ttctgaagag ccgagatcca gctgccgaag tgggagcctg gcgtaccagg
    10741 caagcaaaaa tgaatcgcgc tcagcggctt ctagtatggc atggaaaatc gcttcctcca
    10801 aactccctcc aagtgcacag ccgttcgatg tttcatagac gaagctgtct tcgcgcccca
    10861 ggctgtaata ggcgagcgat tcaggaatga gaatcggccg tttctgcaaa aatgaatagc
    10921 cccataccca gcggagaggg cgggccgggt gaaatggctg aaaaggaaaa tcgggatgca
    10981 tgtattgttc cgcttgatgg agcccgactt ttgccgggtt gagcgcacga tcctttacat
    11041 tttcgtaggt gtcatgtacg accgtccgtt tgccgcgcgg ttcaattccg gaatagcgtt
    11101 ccaaaccctc taaaatggcg gtcaattcgc tgtcttcata cgaatggctc cgccctccga
    11161 caccttcatt tcccgtccat aaaggcatat tgacgatcat atcggcgaac ggcagaatcg
    11221 cgtcataaat tttggtgttg aatatccccg ttctatgatc cagatagtct ttggcgagcg
    11281 tttgttttaa atcgtccgtg tttcgcacgc gaaagctgtc cgggttcgtt ttcagactgg
    11341 gccgaagcga tatccgtgcg gattccgctc cgtcttcagg cagactgccg catatagggc
    11401 atgtcggttc cgggatgaaa gcgtggagcg aactttctaa cgttttcaaa ttgacgatgt
    11461 ataggttttt tttcaaccgg ccgcacccgc cgttcatgat gttgtcgact tctgtgcaga
    11521 tcaggctgac catttggcgg cagccggtct ttgaaaccca cggatcgcgg cttatgccat
    11581 tgcttttttg ttccagttca agggtctctc tgctgtcggg gccggagata taccgcctca
    11641 tatcggcgca ttgggaacat cctgacgctg acggattaac gagcggtccg atgacccctt
    11701 cgccaaaaga tgcaaacccg cgaagccacg gaatccctgc cgcccttagc accttttccg
    11761 cctcgcggta taataaaggc cgccaagcat cgtgcagcac aagagcgaac gcagtctcct
    11821 ccggtatgct gttctcaaaa tcagaccttc ggataatgtt atattcagca gataattgtt
    11881 gtgatgcgtc ttctgccatc aatccttcgc caatgaccaa aatgcagcgg ttcatcaaga
    11941 ttcctccttt cgcaactgca cgcagtaaat gcctgccagt ttttctttga aaaatggttc
    12001 agcaggcagc tcatagacat aaagctgcaa gccgcagttg tttttcaagg cggaaagcag
    12061 tgtttgctgc aaatcagcgg aaacgggggt agcaagcttc aggtcactag actccagcaa
    12121 aacatccgcg cctttcacag ggtctttgtc tgtcagcgcc cgttcgagcg cttttctgag
    12181 agcgaatgtg atgttgagtc cagaacttcc gtaccagcgg ccgcgaattc ccgcccatgc
    12241 gacagggaag ccttgtatgt tttttcctaa accgatttcc ggtttgccgt acaagactgt
    12301 cagcgctttt aaataaaatg cggtatgccg gtcttccatt ccgcctagct gaacgaggga
    12361 aatcgtttct tttccgcttt tgatccgttc tcgcaaccgg tgttccaagc atttctccaa
    12421 tccccttaat acgccttcag ccagcgtttc cccggcggcg atctccccgt tactcggata
    12481 agaacggttc aaccttgatg catacatttc aatacccgcc agcccggctt cccgccgcgc
    12541 ctcttgatgg gtcaaaccga ccgacaccgt cttgggcaaa agctccgcag gtccggaaga
    12601 gagcgggtct gctgtctgaa caaagcattg tgctaaagga agctgccgca aatgtttctc
    12661 ttcccacaga tgaaaaatgc ccgttacagg tgaggtcagt tcactgaaac attgaaataa
    12721 cctgctttct gcttctcttc cggggcgctc cgaaagtttc gcttcaaggt cgcagatgag
    12781 ttcaggcgaa tccttgccgc aagcgaagtc cggatgcgga agaaacatat gccagccgcc
    12841 ttcgagcgtt gccaaatcaa tcagatacac ttgattcttc ttagataatg gtgcaatctc
    12901 agcagttgct ttcatcaatt cgaacacaat aacgtttgcc agcatgtctt tccctgccga
    12961 aggaaaagtt cgaagcgtcc gttcttcatg gagcgcagac cgatggaggc gcctccaggc
    13021 atccttcagg cagccgtctc cttgttgatg aaagactggg cctgccagtc cgacttgttt
    13081 caggcagatc ccgggtatga agcctttgtt ctcttcgagg caaaacgttt gaagatcgcg
    13141 gagctcatct gtgaagccgc ggtcagagac atacagaacc caatcggcag atcgcactgc
    13201 ttcccgccag tgttgcgttt cggcgcagcc aatctccagt ccgctttcgg tttgccctga
    13261 tatttctccc agttcgtcta aagcgtgccc ggatgcatcc gtcacgatcg cacggattct
    13321 tgaaaaaccg gaatcgatca gcgaccggac caattttgtg agaaaggagc cggcccctat
    13381 agccaatatt ttggtttgac gcgacagctg aaagcggtaa gcgccggaat cggcaaagct
    13441 ctcaataaat tcgatttggg cttcaaacgt ttgaagcact gagctttcca gtttgtgcgg
    13501 gtgatcccgg cttacgtcgc gaacgaaccc gtttttataa agcatttctc cgatttcata
    13561 tactctcttt cggtacggag cctgtagccc ttttgtcaag tcttcaagcg aatgttcccc
    13621 gttgaacatc ggcagaagtt tttcgatcca ttgagcaatc gaagatcctt ttatgcgaaa
    13681 cgacccggaa ttatttctaa agtatgcgcc gccgttcgga tcaggaagaa accatgtatc
    13741 ctggtttact ttcaggcgag cggaagcagt caggtgtgtc atgctcttcc tccttcaatg
    13801 ttttaaaaac aaggcatacc attatatgta attttgtttg tcctttatgc aatagaagac
    13861 ccctgcggca aaagaggcag gggaagtctt cttttttata aaaaaactac atgcctccgc
    13921 gccaacagct ccaacagcaa tggcccgcgc agctccaaca actgtggccc atgcagctcc
    13981 aacagctgtg gcccatacag ctccagcagc tgtggcccgc acagctccaa cagctgtgac
    14041 ccgcgcagct ccaacagctg tgacccatgc agctccaaca gctggcacag cttccgcagc
    14101 tccagcagct tgcgcagtgt ttaacattgg cgtgatgacg gtccgcatcc caatgcgtca
    14161 tatcttctgc ctggaattga tccatctcca acgactgcag ttcatcatgg aatggttgca
    14221 tttaatatcc ccctcatcga taaaattttt tgaccaaaac acaataaaaa aagaatgaaa
    14281 cataagcaaa gtcagattaa gtcaaatacc ccgggtactc acaagatcaa attatgaggt
    14341 ctgttaggtg gttgttacta atttgaacgc ctatttttcc tgttattgga tttcgctgga
    14401 gaggggcttt tattttgcgg cagtttattg atataaagat cgttgggact gaagagaggg
    14461 gggacactaa gtaaaaccaa gaatgcgggg caaggcggag aaagaaatca attgtaagtc
    14521 atgtggagtg aaagtcaaat ttcaagggaa acgtctcaag tgaagaaagc ctagaggata
    14581 aaggtaacca ttcggcttag caggaaaaaa tcaattggcg ttgtatatag cagtagagga
    14641 tcattcgcgg gaacagtgcc cttgcagttt tatactgatg caaatgctta tgtatgactg
    14701 caaaaacagg ttctttctac aagtatgttt tcatagagaa ggagagattg cattgattca
    14761 ataataaatg cggtcatagt attaggagtc ttccctatcc attgtgtggg gcatgatcta
    14821 tattatgaac aggagaagat cgtaacatga tgagaggccg gacatttgac cggcctcttt
    14881 taaaatcgtt attttacaat cagcacaggg atctccgatt ttgtcgatat cttgtcactg
    14941 acactgccaa acaggagctt tttcaggcgg ttttggtcgc gcgtacccgt gatgacaagg
    15001 tcagcgccga tattttccgc atgttgtaga actgcgttgg ccgggtcgcc ttccaacacc
    15061 tctatttccg cgtcgtactg gttttcgctt aatatgattt tcgctgccgc aatcgcttct
    15121 tccgcgctgt cctcatagat catgggttca ccggccaagt ctgaatcgtg ggggacccgg
    15181 ggcgcggccg ggaagccgct gtaaaggtat ggcgcgccgg cagcgggtct ttcagtcgca
    15241 gcctctgttc tcacttgcct cggttcatgg acatgggaga cggtcaattg cgagccgagc
    15301 cttttcgaga ggtcgatcgc ttttttcagc gcttttttgc tttcctcttt tccgtcaaac
    15361 gcgacaatga tccggtcagc tttaaacaaa ttgatcattc ctttcagaat ggatttactt
    15421 ttatattacc cgttttccca acaaatctaa cgaaatatga gaatatgaat caaaagcccg
    15481 ccattcgcca aaaaaacaaa ttgacaaata aagggccgta ctataagatg gaaaatatta
    15541 ataagattgg agggtatcgt catgtttaga aatatcaaag catcagttca acaacaaaag
    15601 caccttaacg tgacattttt ataccttcct tacgatcagg gctctgtttc actttaacaa
    15661 ttttcaaaag gaaggcgcat gtcgcgtgaa caagcgtaca tgcgcctttt tatatgaaaa
    15721 aaggcatgct ggtacacagt gtgccttttt tttctgagaa aaaacattct gttcccgatg
    15781 cggagcagca tgtttttcta ataaataaac cgcacataag gaggaatttt ttatgccgat
    15841 tatcagaaaa aacgaaatca aagattgtaa ggaaaaactt gaaggcggct aaaaaaggag
    15901 aggatattag atgttttctg ttttatggaa gctgggctgg ttttttaaag cctcttggcg
    15961 gcgctacacg atagcagtcg tcctattgat tattgtaaac gtattggaaa tgtttccgcc
    16021 gaagctgctt ggcaacgcga ttgacgacat gcaggcgggc actttttcaa aggccggcat
    16081 gctcggctat atcggtttat ttctcgcgct tggcgcagtt gtttatatct tgtcctatta
    16141 ttggatgtat cagctgtttg ggggagcgaa ccttgtcgaa aaaatcctca gatccaagct
    16201 gatgggccat ttgctgaaaa tgaccccgtc tttttacgag aaaaaccgca caggggattt
    16261 gatggcgagg gcgacaaatg atttaaaagc gatttccatg acggcgggct tcggcatttt
    16321 gaccttggtc gattcgacga tgtatatgct gacgattctt ttgacgatgg gttttttgat
    16381 cagctggaag ctgacgcttg cttcgatcat tccccttccg ctgatggcgg ctgccatcag
    16441 catttacggg aaaaaaattc atgagcgttt cacggaagcg caggatgcgt ttggcgcttt
    16501 aaatgatcga gtgcttgagt ccgtgtcagg ggtaagggtg atccgggcct atgtacagga
    16561 gaaaaatgat gtcagccggt tcaacagcat gacggctgat gtgtacaaga aaaatatgaa
    16621 agtcgctttg atcgattcgc tgttcgaacc gacggtgaag tttttggtcg ggatcagcta
    16681 tttaatcggt cttggctacg gcgcctatct tgttttccgc agccagctga cattgggtga
    16741 actcgtctct ttcaacgtgt acctcggcat gctgatctgg ccgatgtttg cgatcggaga
    16801 actgatcaat gtcatgcaga ggggaaatgc ttcgcttgac agagtaaatg aaacattggc
    16861 atatgagcct gatgtgagag agcccgccga acctgaagca gcggaaccgg gcgatattgt
    16921 gtttgacggg gtcgctttta cgtacccgag ctccgcgtcg gaaaacctgg ccgatatttc
    16981 atttaccgta ttagaaggac agacggtcgg agtcgtcgga aagacgggaa gcggcaaaac
    17041 gacgttagtc aagcagctgc tgaggcagta cccgaaagga aaaggaacga tcaccatttc
    17101 gggcgtgccg attgaccgcc tgccgcttga tcagcttcgc agctggatcg ggtatgtgcc
    17161 tcaggaccac gtgttgtttt caaaatcggt gaaagacaat attttgttcg gcggacgact
    17221 cgccgaggaa cgcgatttat acgatgtcat ctctgcagca catctgaaaa aggatattga
    17281 gatgctttca gacggtttgg agacaatggt cggagagaag ggcgtcgctt tatccggggg
    17341 gcagaaacaa aggatttcaa ttgcgagagc gatgattgcg gagccccata ttttgatctt
    17401 ggatgattcg ctgtccgccg tcgatgcgaa aacggaagcg gcgattattg aaaacatccg
    17461 cagcaggcgg aaaggcaaaa cgacctttat tacatcacat cggatgtcgg ccgtcgaaca
    17521 cgccgatttc attctcgtca tggaaaatgg aaggatcgtt gaaagaggga cgcatcagga
    17581 actgatcagc cggaaaggct ggtattttga acaatacgaa gcacagcagc ttccttcggg
    17641 agaagaaggg gggactgtag catgacaaca ggaaaaaggc ttttccaata tgcgcttctt
    17701 tacaaaaaaa ttctcatctg ggcgctcgtc atgctgacga ttgccgtcac agccgagctg
    17761 acgggaccga tgatcgccaa aaagatgatc gacgatcata ttctcggaat tgaaaaaacg
    17821 tggtatgaaa caacagagga gacgaaatat accgtttcct ataaaggaaa ggaatatatc
    17881 agggaggaca ggacagactc ttcagctgaa aagctgcagg aagttcacat ctttcaagtc
    17941 ggcatgaact actactttgt ggaggaaccg gtttcctttg acggagagcg gacggtatcc
    18001 ggagaagagc tgagaatgac aagcggagac cggacggaaa cctacaaggc cgatcgcctg
    18061 tctttgtcag aagtgtatgc tttttacgag cctgaaatag gagggctgat ttcactcgtt
    18121 tctatttatt tcggccttct cgtcttctcg atctttttcc attacggcca attctacctc
    18181 ttgcagatga gcgcaaaccg catcattcaa aagatgaggc aggatgtatt cgccaacatt
    18241 caaaggctac ctatccgcta ttttgataat ttgccggcag gaaaaatcgt tgcaagggtg
    18301 acgaatgata ccgaagcgat ccgcgacctg tatgtgaccg ttctttcgac gtttgtcaca
    18361 aatatcattt atatggccgg aatattcgcc gcgttgtttt tccttgatgt caggctggcc
    18421 ggcgtctgtc tgttgatttt gcccctgatt gtcatttggg cggccgttta tcgaaaattc
    18481 gcttctggct acaatcataa actcaggtca atcaacagcg agatcaacgc caaaatgaat
    18541 gaatcgattc aaggcatgcc gattattcag gcattccgtc gcggacagga cacaaaagaa
    18601 gaatttgaac agctgaacga gagccacttt cattaccaaa ataaaatgct gaaattgaat
    18661 tcgcttatgt cccacaactt ggtcaacatt ctcagaaatg tgatgttcac cgctttaatc
    18721 tggtatttcg ggggagctgc cctgaacgcg gaaggaatga tttcaatcgg cgtcctttat
    18781 gcattcgttg attacttgaa tcgtttattt cagccgatta cgggcattgt caaccagttt
    18841 gccaagcttg aattggctcg cgtatcatcg gagcgggttt tccgcctgct ggatgagcca
    18901 ggcgtcgacg tcaaagagcc gggcagcgaa agagcgcggg ggcgagtcgt atttgaagat
    18961 gtatctttcc gctatcatga cggtgaagat gtgctgaaaa acatctcatt tgaagcgcag
    19021 caaggggaga ccgttgcatt ggtcggccat acaggctcag gaaaaagctc cattttaaat
    19081 gtacttttcc gcttttacga tattgaaaag ggcgatgtca aaatcgacgg cagaagcata
    19141 tacgatatgt caaggcagga aatcagaaag cagatgggca tcgttctcca ggatccttac
    19201 ttattttccg gcacgattgc ttcaaatgtc agccttgaca atgctgattt gaccagagat
    19261 caaatagaag ccgccttgaa acaggttggg gcacttgaaa tgctcgcccg cctgccgaaa
    19321 ggtcttgacg agccggtcat cgaaaaagga agcacccttt cgtcagggga aagacagctg
    19381 atctcgtttg cgcgtgcgct ggcatatgat ccggctattc ttattttaga cgaggcaacg
    19441 gcccatatcg atacggaaac agaagcggtc attcaaaaag cgcttgatgt tgttaaacaa
    19501 gggcgcacga cctttatcat cgcccacagg ctgtcaacga tcaaaaacgc cgaccagatt
    19561 ctcgttcttg aaaaaggccg gattatcgaa aggggaaatc atgaagagct gatgaagcaa
    19621 aaaggacaat actatcaaat gtatgaactg caaaagggaa aaggaaccct gacagggtaa
    19681 gccggatctt cacccggctt taataagcaa gccccaccct tgccttgaca aactggtctg
    19741 attcaagctg tttgaaaaga aaatgggcgg tgtcgccggt cgatatttct tttccgccgt
    19801 ccggcagaac atcctgttca aaacggtatg tcttcaatgc cggcccgtcg gggagatatg
    19861 tcgggcagac gatcgtccaa tccaattcag actcgcggag acgttcgtac acacgggcat
    19921 gttcttgcgc tgcgcgcgcc gagcgccgtt ttgattcgtt tgtttcaaag cggtaaaggt
    19981 cctggttctg cctcgcgttt aaaataccgg ccgttccgat ggtaatcagc cgtttaatcc
    20041 gatgtgcgtt catggcattt atcatatgtt cgatggagac ggtcaatgta tcgtctccat
    20101 ctgtgtttaa acagctgaca acgatatccg aatcttttat taaagactcg acgtcatgct
    20161 ggttcctggc gttccctgta agcgcttggc agcatttatc cggaatgcgg gcgccttccg
    20221 tcctcctaac aagtgcgtaa acggaataac gcccatcctc ttcaacaaaa ttgagaaagg
    20281 cctgtccgac acggcctgta cctccaaaaa gcgcaatttt caacataatc actcccatcg
    20341 gatctatcat acgtcagatc gtccggaaga aaaagccccg cgaaagcaaa aagttccatg
    20401 ataagggtgg acatttgaga catactcatt caatagagaa atcccgacaa attgaatcaa
    20461 ttcccaattg atgctcaaca tcagctgcat gccgactcct cctttatatc agcatatgaa
    20521 aaaaggagaa gcgggtgcgg gctttcataa gatatgccag aggtgcgggc cgccgccccg
    20581 gcaatgaatg tgaaggtttg tcgacacgct aaagaaggtg caggatatgc accttctgtt
    20641 atccatgaat atgaagttgt ttaaaattgt tgaccgccca tagatgcttg agcttgggaa
    20701 actaaacgtt ttgtaatttc tccgccgaca gaaccgtttg cacgggaagt cgtgtcagcg
    20761 ccgaggttta cgccgaattc agaagcaatt tcgaatttca tttgttcgat cgcttgagct
    20821 gctcctggga caaccagttg atttgaagaa ttttgattag ccatttgtat caaactcctt
    20881 tataaaaatg gtatggttgg gctgactgga gttgcaccag ctgccggctt tcaccaaaag
    20941 aaaaccgctg ccttctcggc taaagcccaa tgttggtttg tactacgtat tatggtggat
    21001 tcgataaaat aaatgcgtgc ttcaatctgg taaatgttga aaggcgaaaa ggccgggaat
    21061 ggggcaagct aaggaaaaaa gcaggaggat gaagcagatg atgtgtccag tgtgcaatgg
    21121 gattctcgtc cagacaaggc attgtccgaa gtgcggcggg gaaatggcgg acgcggggag
    21181 agcaaccgat tttttcggtc cgtacagtcc gtatatggag tttgattcat ttaaacaaac
    21241 gcaaaccgta tgcgttcatt tatatacttg ccaggactgt acttatgaag aaaccgttga
    21301 aattgaaacg accgaagcat agcagcacgg agggccgcag catgcttcgg tcatggagag
    21361 tgtttaaatc cgctattctt cagaacggat gcgaagctcc gtttctttat caaagaagtg
    21421 ggctttattc atgtccagcg caagaggaag cgtatcgccg gcctggacgt cggttcttga
    21481 atcgactctg gcgatgaacg gctgcgtgcc ggcttgcgaa taaagcatcg tttcggcgcc
    21541 catcagctca gctacctcaa ttttcgcatc gatttttgag tcttttgacg cttcaatgaa
    21601 aacaggctcg tcatggatat cctcaggtct gattcccatg atgatttcct tgccggcata
    21661 gccttggctg cgcagaactt tcatttttcc ttccggcacg cgaaccgaaa cgccgtcaaa
    21721 tgtaaacaag tcttctttta gagtgccggt gaaaaagttc attgcgggag aaccgataaa
    21781 gccgccgaca aacacgtttt ccggattttc atagacttcc ttcggcgcgc cgacctgctg
    21841 gatgattccg tctttcatga cgacgagccg cgtagccatc gtcatcgctt cagtctggtc
    21901 gtgggtgaca tagatggtcg tcgtctgcag gcgct
//
