LOCUS       NZ_QGHB01000032         8371 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Lentzea atacamensis strain DSM 45480 Ga0215650_132, whole genome
            shotgun sequence.
ACCESSION   NZ_QGHB01000032
VERSION     NZ_QGHB01000032.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea atacamensis
  ORGANISM  Lentzea atacamensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 8371)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8371)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Expected Final Version            :: No
            Genome Coverage                   :: 90.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003148865.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:35:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,333
            CDSs (total)                      :: 9,254
            Genes (coding)                    :: 9,110
            CDSs (with protein)               :: 9,110
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 6 (5S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 32 of 144
            Pseudo Genes (incomplete)         :: 121 of 144
            Pseudo Genes (internal stop)      :: 2 of 144
            Pseudo Genes (multiple problems)  :: 11 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:50:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 8371
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QGHB01000032.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..8371
                     /culture_collection="DSM:45480"
                     /db_xref="taxon:531938"
                     /mol_type="genomic DNA"
                     /organism="Lentzea atacamensis"
                     /strain="DSM 45480"
                     /submitter_seqid="Ga0215650_132"
                     /type_material="type strain of Lechevalieria deserti"
     gene            <1..>8371
                     /locus_tag="C8D88_RS45820"
     region          1..8371
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..8371
                     /SMILES="NC(CCCN)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..8371
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:>8371](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..>8371
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             1..>8371
                     /NRPS_PKS="Domain: PCP (278-345). E-value: 2.2e-25. Score:
                     80.6. Matches aSDomain: nrpspksdomains_C8D88_RS45820_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (358-630). E-value:
                     5.3e-111. Score: 363.6. Matches aSDomain:
                     nrpspksdomains_C8D88_RS45820_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (636-785). E-value: 6.3e-33.
                     Score: 105.7. Matches aSDomain:
                     nrpspksdomains_C8D88_RS45820_TIGR01720.1"
                     /NRPS_PKS="Domain: Condensation_DCL (793-1082). E-value:
                     7.1e-98. Score: 319.3. Matches aSDomain:
                     nrpspksdomains_C8D88_RS45820_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1251-1638). E-value: 7e-91.
                     Score: 296.8. Matches aSDomain:
                     nrpspksdomains_C8D88_RS45820_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1746-1813). E-value: 1.3e-26.
                     Score: 84.6. Matches aSDomain:
                     nrpspksdomains_C8D88_RS45820_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (1825-2105). E-value:
                     8.2e-115. Score: 376.2. Matches aSDomain:
                     nrpspksdomains_C8D88_RS45820_Epimerization.2"
                     /NRPS_PKS="Domain: TIGR01720 (2110-2258). E-value: 8.6e-35.
                     Score: 111.8. Matches aSDomain:
                     nrpspksdomains_C8D88_RS45820_TIGR01720.2"
                     /NRPS_PKS="Domain: Condensation_DCL (2266-2557). E-value:
                     3.6e-101. Score: 330.1. Matches aSDomain:
                     nrpspksdomains_C8D88_RS45820_Condensation_DCL.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="C8D88_RS45820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_146231940.1"
                     /sec_met_domain="AMP-binding (E-value: 2.5e-99, bitscore:
                     318.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.6e-18, bitscore:
                     51.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 8.8e-67, bitscore:
                     211.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVPGMLLRDLAAHCREAGPVKSLRLVISGTDMWTHDALTGAVAD
                     VAPDALAGNVFGVTEAAIDSIFHPVGEDHPAAVVPIGKPLAGAQAFVVDGTLRPVPVGV
                     PGELLVGGGGVARGYAGRPDLTAARFVPDVFGGSGGRLYRTGDRARWRADGVLEFLGRV
                     DEQVKIRGYRVEPGEVEVVIGDHPGVRDVVVVARDGGPHGGKRLVAYVVAESEDVSGSV
                     LRAWLRERVPDYLVPSVFVALDRLPLTPNGKVDRRGLPEPEPEAVAETCVAPRTAVEET
                     LAAVWSGVLGVGRVGVHDNFFELGGDSILSLQIVARVRAAGLGVDVADVFAHQTIAELA
                     LAVRDTPAVSSAEQGVVNGPVPFTPIQRWFLAQDIPDRDHWNWSGVFELAPGTDPDRLV
                     SALNAVVAHHDALRIRFTPEGQYNAGIEAADLRVVAVHDDEVPAEMTAAQKSLRLADGP
                     LIAAVLFDRGDEPAWLGLTVHHLVMDGVSWNVLLEDLDTAYRSEALGPKTSSFQQWAEH
                     LLELEVGGEREHWVAATSDVVALPVDQDGPNTEVSGAVVRTWLDAGTTAALFGEAHKAY
                     RTQANDLLLAALANVLGEWAGTDHITVDLESHGREGLDLSRTVGWFTSIFPVRLSRHTD
                     PGATVKTVKEQLRAVPRRGVGYGVLRWLRGELADAPDRPVLFNYLGAFDAVDSVGLIRR
                     ELPAELAGPMQGPGGTRAYPLQLEVVRADDGRLRIDWLHSTNVHLPGTVERVAARYVEA
                     LRELVTHCQSGVAGFTPSDFPLASLTQGEVDGLAERYPLVDVYRLAPVQSGMLFGVVGS
                     PVDGLYWGQGVYDIAGPVDAERLARAWREVIGRHAALRSGFVWEGVSEPVQVVLADVEV
                     PLQLRDWSDLDGDTQQSRLRELLAEDRALGFDLAAPPLTRLYLVDRGKGRLWLVWGLYQ
                     GLCDGWSLPVVVDEVFAAYDGETLAPARPYREFIGWLDGRDPDESEGFWRTYLDGFEAP
                     TPLPVDRLAASHYAQDRRKTMLDEGVTTRLVELARRERVTLSTVVQAAWAKVLSASSGE
                     DDVVFGLTVSGRPAELAGVESMVGLFINTLPVRAVVPVDTPFASWLRELQDNQVALQRF
                     EYTPLVDVQRWSAVPGGRALFDSIVVFGNYPHQDLPDDLAAGYATVDSVEQGNYPLTFA
                     VDLERRLRIEAEFSTAAFEAVTVERILDQLVVVLTAVAERPELAVVDVPLQRPEQAAQL
                     VAWGETPVPVAEASVPELIHSWADSAEVAVVCGDERLTFAELDARSAGLAARLRQAGVT
                     VESPVAVLVPRGIELAVAFQGVLRSSGVYVPINPGLPAERLAFLLEDVGAVAAVTTSAL
                     AGELAAFSGEVLVMDDTVLDALSVHMNPDALAYIAYTSGSTGRPKGVAVTHRALSSYVA
                     GWRDGLRALGGPGTVLSMSGPGFDVSIGDMTRALAFGQTVVFLPHDEHVSVESLHATLV
                     EHQIEVAEIVPGMLLRDLAAHCRVAGPVESLRLVISGTDMWTHDALTSAVAEVAPNAVP
                     GNVFGVTEAAIDSIFHAVIEDDPAAVVPIGTPLAGARAVVVDSAMRPVPIGVPGELLVG
                     GAGVARGYLGRPGLTATRFVPDLFGAAGGRLYRTGDRARWRADGTIEFLGRVDEQVKIR
                     GYRVEPGEVEVVIGDHPGVRDVVVVARDGGPHGGKRLVAYVVAESEDVSGSVLRAWLRE
                     RVPDYLVPSVFVALERLPLTPNGKVDRRGLPHPEPETAGEAYVAPRTAAEETLAAVWSG
                     VLGVERVGVHDNFFELGGDSILSLQIVARVRAAGLGVDVADVFAHQTVAELAGVVRDTP
                     SVTLADQGVVTGPVPLTPIQHWFLAEDIPNRDHWNWSGMFELAPGTDPDRLSRALDVLV
                     AHHDALRIRLDANGQYNAPVDGGSVLRVVEVADDEAVVAHMTAAQTSLRLVDGPLIAAV
                     FFDRGSQPAWLGLTVHHLVMDGVSWNVLLEDLDTACAGRALGPKTTSFQQWAEVLRELD
                     AQAERETWLAQTADVVALPQDRQGLNTETSAGVVRSWLDPETTAALLGDAHRAYRTQGN
                     DLLLAALAQALGEWAGTGHVTVDLESHGREAVADGVDLSRTVGYFTSIFPVRLTHEDDP
                     AAAIKAVKEELRSVPRRGVGYGVLRWLQNDLADAPDRPVLFNYLGAFDAVDSLGLIRRE
                     LPAELAGPSEGSGGTRSHVLQIEAQQDTDGRLRVDWHFSHNLHDTVTVERVAARYVEAL
                     RGLVGHCRSAGGFTPSDFPLASLTQVEVDGLAERYPLVDVYRLAPVQSGMLFGVAGSPV
                     DGLYWGQGVYDLAGPIDAERLADAWRSVIARHAALRSGFVWEGVSEPVQIVLADVNVPL
                     EQRDWSGLDDAAQQEQLQALLASDRALGFDLAVPPLTRLYLVDRGEDRLWLVWGLYQGL
                     CDGWSLPVVMDEVSATYQGQSLEPVRSYRDFIAWLGRRDPSESEGFWRTYLDGFEAPTP
                     LPVDRLASSHYDQDRRRMRLDETVTAKLVELARRERVTLSTVVQAAWALLLSTYSGDDD
                     VVFGLTVSGRPAELAGVESMVGLFINTLPVRAAVPGDTSFAEWLPSLQDNQVALQRFEY
                     TPLVDVQRWSAVPHGRALFDSIVVFGNYPQEELPEDLSGLQAADSVEQGNYPLTFAVDL
                     ERTLRVEAEFSTAAFDAVTVERILDQLAVVLTAVAERPELAARDVPLQRPEQAAELVAW
                     GATPVPVAERPVPDLIDDWARTSAEIAVICGDERLTFAELGTRADALAARLQQAGVTVA
                     SPVAVLVPRGIELAVAFQGVLRSGGVYVPVN"
     CDS_motif       301..390
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0001"
                     /evalue="6.80E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="130"
                     /protein_start="100"
                     /score="47.2"
                     /tool="antismash"
                     /translation="PVGVPGELLVGGGGVARGYAGRPDLTAARF"
     CDS_motif       475..540
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0002"
                     /evalue="2.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="180"
                     /protein_start="158"
                     /score="35.8"
                     /tool="antismash"
                     /translation="FLGRVDEQVKIRGYRVEPGEVE"
     aSDomain        835..1035
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS45820_PCP.1"
                     /evalue="2.20E-25"
                     /label="C8D88_RS45820_PCP.1"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="345"
                     /protein_start="278"
                     /score="80.6"
                     /tool="antismash"
                     /translation="EETLAAVWSGVLGVGRVGVHDNFFELGGDSILSLQIVARVRAAGL
                     GVDVADVFAHQTIAELALAVRD"
     aSModule        835..2355
                     /domains="nrpspksdomains_C8D88_RS45820_PCP.1"
                     /domains="nrpspksdomains_C8D88_RS45820_Epimerization.1"
                     /domains="nrpspksdomains_C8D88_RS45820_TIGR01720.1"
                     /incomplete
                     /locus_tags="C8D88_RS45820"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       898..927
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0003"
                     /evalue="1.50E-01"
                     /label="PCP_mE"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="309"
                     /protein_start="299"
                     /score="5.5"
                     /tool="antismash"
                     /translation="NFFELGGDSI"
     aSDomain        1075..1890
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS45820_Epimerization.1"
                     /evalue="5.30E-111"
                     /label="C8D88_RS45820_Epimerization.1"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="630"
                     /protein_start="358"
                     /score="363.6"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVMDG"
                     /tool="antismash"
                     /translation="GPVPFTPIQRWFLAQDIPDRDHWNWSGVFELAPGTDPDRLVSALN
                     AVVAHHDALRIRFTPEGQYNAGIEAADLRVVAVHDDEVPAEMTAAQKSLRLADGPLIAA
                     VLFDRGDEPAWLGLTVHHLVMDGVSWNVLLEDLDTAYRSEALGPKTSSFQQWAEHLLEL
                     EVGGEREHWVAATSDVVALPVDQDGPNTEVSGAVVRTWLDAGTTAALFGEAHKAYRTQA
                     NDLLLAALANVLGEWAGTDHITVDLESHGREGLDLSRTVGWFTSIFPVRL"
     CDS_motif       1090..1116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0004"
                     /evalue="1.30E-02"
                     /label="NRPS-E1"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="372"
                     /protein_start="363"
                     /score="8.9"
                     /tool="antismash"
                     /translation="TPIQRWFLA"
     CDS_motif       1153..1248
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0005"
                     /evalue="2.10E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="416"
                     /protein_start="384"
                     /score="20.1"
                     /tool="antismash"
                     /translation="GVFELAPGTDPDRLVSALNAVVAHHDALRIRF"
     CDS_motif       1426..1485
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0006"
                     /evalue="4.50E-10"
                     /label="NRPS-E2"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="495"
                     /protein_start="475"
                     /score="31.8"
                     /tool="antismash"
                     /translation="LTVHHLVMDGVSWNVLLEDL"
     CDS_motif       1747..1785
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0007"
                     /evalue="1.60E-01"
                     /label="Cy4"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="595"
                     /protein_start="582"
                     /score="5.3"
                     /tool="antismash"
                     /translation="LLLAALANVLGEW"
     CDS_motif       1840..1890
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0008"
                     /evalue="5.60E-09"
                     /label="NRPS-E5"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="630"
                     /protein_start="613"
                     /score="27.9"
                     /tool="antismash"
                     /translation="DLSRTVGWFTSIFPVRL"
     aSDomain        1909..2355
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS45820_TIGR01720.1"
                     /evalue="6.30E-33"
                     /label="C8D88_RS45820_TIGR01720.1"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="785"
                     /protein_start="636"
                     /score="105.7"
                     /tool="antismash"
                     /translation="GATVKTVKEQLRAVPRRGVGYGVLRWLRGELADAPDRPVLFNYLG
                     AFDAVDSVGLIRRELPAELAGPMQGPGGTRAYPLQLEVVRADDGRLRIDWLHSTNVHLP
                     GTVERVAARYVEALRELVTHCQSGVAGFTPSDFPLASLTQGEVDG"
     CDS_motif       1927..1989
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0009"
                     /evalue="2.60E-10"
                     /label="NRPS-E6"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="663"
                     /protein_start="642"
                     /score="32.4"
                     /tool="antismash"
                     /translation="VKEQLRAVPRRGVGYGVLRWL"
     CDS_motif       2023..2043
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0010"
                     /evalue="4.30E-01"
                     /label="NRPS-E7"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="681"
                     /protein_start="674"
                     /score="4.0"
                     /tool="antismash"
                     /translation="VLFNYLG"
     aSDomain        2380..3246
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS45820_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="7.10E-98"
                     /label="C8D88_RS45820_Condensation_DCL.1"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1082"
                     /protein_start="793"
                     /score="319.3"
                     /specificity="C activity: inactive"
                     /specificity="Active site motif: YQGLCDG"
                     /tool="antismash"
                     /translation="DVYRLAPVQSGMLFGVVGSPVDGLYWGQGVYDIAGPVDAERLARA
                     WREVIGRHAALRSGFVWEGVSEPVQVVLADVEVPLQLRDWSDLDGDTQQSRLRELLAED
                     RALGFDLAAPPLTRLYLVDRGKGRLWLVWGLYQGLCDGWSLPVVVDEVFAAYDGETLAP
                     ARPYREFIGWLDGRDPDESEGFWRTYLDGFEAPTPLPVDRLAASHYAQDRRKTMLDEGV
                     TTRLVELARRERVTLSTVVQAAWAKVLSASSGEDDVVFGLTVSGRPAELAGVESMVGLF
                     INTLPVRA"
     aSModule        2380..6774
                     /complete
                     /domains="nrpspksdomains_C8D88_RS45820_Condensation_DCL.1"
                     /domains="nrpspksdomains_C8D88_RS45820_AMP-binding.1"
                     /domains="nrpspksdomains_C8D88_RS45820_PCP.2"
                     /domains="nrpspksdomains_C8D88_RS45820_Epimerization.2"
                     /domains="nrpspksdomains_C8D88_RS45820_TIGR01720.2"
                     /locus_tags="C8D88_RS45820"
                     /monomer_pairings="Orn -> D-Orn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2386..2421
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0011"
                     /evalue="1.90E-02"
                     /label="C1_dual_004-017"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="807"
                     /protein_start="795"
                     /score="8.3"
                     /tool="antismash"
                     /translation="YRLAPVQSGMLF"
     CDS_motif       2449..2565
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0012"
                     /evalue="9.30E-16"
                     /label="C2_DCL_024-062"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="855"
                     /protein_start="816"
                     /score="50.1"
                     /tool="antismash"
                     /translation="LYWGQGVYDIAGPVDAERLARAWREVIGRHAALRSGFVW"
     CDS_motif       2794..2847
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0013"
                     /evalue="5.30E-07"
                     /label="C3_DCL_135-156"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="949"
                     /protein_start="931"
                     /score="22.2"
                     /tool="antismash"
                     /translation="LCDGWSLPVVVDEVFAAY"
     CDS_motif       2875..2913
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0014"
                     /evalue="2.80E-01"
                     /label="C4_DCL_171-183"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="971"
                     /protein_start="958"
                     /score="4.8"
                     /tool="antismash"
                     /translation="PYREFIGWLDGRD"
     CDS_motif       3079..3132
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0015"
                     /evalue="5.30E-02"
                     /label="Cy4"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1044"
                     /protein_start="1026"
                     /score="6.8"
                     /tool="antismash"
                     /translation="RVTLSTVVQAAWAKVLSA"
     CDS_motif       3148..3243
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0016"
                     /evalue="1.80E-21"
                     /label="C5_DCL_263-294"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1081"
                     /protein_start="1049"
                     /score="68.6"
                     /tool="antismash"
                     /translation="DVVFGLTVSGRPAELAGVESMVGLFINTLPVR"
     CDS_motif       3292..3414
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0017"
                     /evalue="1.10E-19"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1138"
                     /protein_start="1097"
                     /score="62.9"
                     /tool="antismash"
                     /translation="QDNQVALQRFEYTPLVDVQRWSAVPGGRALFDSIVVFGNYP"
     aSDomain        3754..4914
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS45820_AMP-binding.1"
                     /evalue="7.00E-91"
                     /label="C8D88_RS45820_AMP-binding.1"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1638"
                     /protein_start="1251"
                     /score="296.8"
                     /specificity="substrate consensus: Orn"
                     /tool="antismash"
                     /translation="EVAVVCGDERLTFAELDARSAGLAARLRQAGVTVESPVAVLVPRG
                     IELAVAFQGVLRSSGVYVPINPGLPAERLAFLLEDVGAVAAVTTSALAGELAAFSGEVL
                     VMDDTVLDALSVHMNPDALAYIAYTSGSTGRPKGVAVTHRALSSYVAGWRDGLRALGGP
                     GTVLSMSGPGFDVSIGDMTRALAFGQTVVFLPHDEHVSVESLHATLVEHQIEVAEIVPG
                     MLLRDLAAHCRVAGPVESLRLVISGTDMWTHDALTSAVAEVAPNAVPGNVFGVTEAAID
                     SIFHAVIEDDPAAVVPIGTPLAGARAVVVDSAMRPVPIGVPGELLVGGAGVARGYLGRP
                     GLTATRFVPDLFGAAGGRLYRTGDRARWRADGTIEFLGRVDEQVKIR"
     CDS_motif       3913..3948
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0018"
                     /evalue="6.70E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1316"
                     /protein_start="1304"
                     /score="4.2"
                     /tool="antismash"
                     /translation="GVLRSSGVYVPI"
     CDS_motif       4123..4182
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0019"
                     /evalue="2.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1394"
                     /protein_start="1374"
                     /score="29.5"
                     /tool="antismash"
                     /translation="AYIAYTSGSTGRPKGVAVTH"
     CDS_motif       4705..4794
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0020"
                     /evalue="2.50E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1598"
                     /protein_start="1568"
                     /score="51.7"
                     /tool="antismash"
                     /translation="PIGVPGELLVGGAGVARGYLGRPGLTATRF"
     CDS_motif       4879..4944
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0021"
                     /evalue="2.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1648"
                     /protein_start="1626"
                     /score="35.8"
                     /tool="antismash"
                     /translation="FLGRVDEQVKIRGYRVEPGEVE"
     aSDomain        5239..5439
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS45820_PCP.2"
                     /evalue="1.30E-26"
                     /label="C8D88_RS45820_PCP.2"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1813"
                     /protein_start="1746"
                     /score="84.6"
                     /tool="antismash"
                     /translation="EETLAAVWSGVLGVERVGVHDNFFELGGDSILSLQIVARVRAAGL
                     GVDVADVFAHQTVAELAGVVRD"
     CDS_motif       5302..5331
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0022"
                     /evalue="1.50E-01"
                     /label="PCP_mE"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1777"
                     /protein_start="1767"
                     /score="5.5"
                     /tool="antismash"
                     /translation="NFFELGGDSI"
     aSDomain        5476..6315
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS45820_Epimerization.2"
                     /evalue="8.20E-115"
                     /label="C8D88_RS45820_Epimerization.2"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2105"
                     /protein_start="1825"
                     /score="376.2"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVMDG"
                     /tool="antismash"
                     /translation="TGPVPLTPIQHWFLAEDIPNRDHWNWSGMFELAPGTDPDRLSRAL
                     DVLVAHHDALRIRLDANGQYNAPVDGGSVLRVVEVADDEAVVAHMTAAQTSLRLVDGPL
                     IAAVFFDRGSQPAWLGLTVHHLVMDGVSWNVLLEDLDTACAGRALGPKTTSFQQWAEVL
                     RELDAQAERETWLAQTADVVALPQDRQGLNTETSAGVVRSWLDPETTAALLGDAHRAYR
                     TQGNDLLLAALAQALGEWAGTGHVTVDLESHGREAVADGVDLSRTVGYFTSIFPVRLT"
     CDS_motif       5491..5520
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0023"
                     /evalue="2.30E-03"
                     /label="NRPS-E1"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1840"
                     /protein_start="1830"
                     /score="11.1"
                     /tool="antismash"
                     /translation="LTPIQHWFLA"
     CDS_motif       5563..5643
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0024"
                     /evalue="2.70E-05"
                     /label="C2_DCL_024-062"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1881"
                     /protein_start="1854"
                     /score="16.4"
                     /tool="antismash"
                     /translation="FELAPGTDPDRLSRALDVLVAHHDALR"
     CDS_motif       5836..5895
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0025"
                     /evalue="4.50E-10"
                     /label="NRPS-E2"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="1965"
                     /protein_start="1945"
                     /score="31.8"
                     /tool="antismash"
                     /translation="LTVHHLVMDGVSWNVLLEDL"
     CDS_motif       6157..6195
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0026"
                     /evalue="6.50E-01"
                     /label="Cy4"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2065"
                     /protein_start="2052"
                     /score="3.4"
                     /tool="antismash"
                     /translation="LLLAALAQALGEW"
     CDS_motif       6262..6312
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0027"
                     /evalue="4.10E-07"
                     /label="NRPS-E5"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2104"
                     /protein_start="2087"
                     /score="22.3"
                     /tool="antismash"
                     /translation="DLSRTVGYFTSIFPVRL"
     aSDomain        6331..6774
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS45820_TIGR01720.2"
                     /evalue="8.60E-35"
                     /label="C8D88_RS45820_TIGR01720.2"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2258"
                     /protein_start="2110"
                     /score="111.8"
                     /tool="antismash"
                     /translation="AAAIKAVKEELRSVPRRGVGYGVLRWLQNDLADAPDRPVLFNYLG
                     AFDAVDSLGLIRRELPAELAGPSEGSGGTRSHVLQIEAQQDTDGRLRVDWHFSHNLHDT
                     VTVERVAARYVEALRGLVGHCRSAGGFTPSDFPLASLTQVEVDG"
     CDS_motif       6349..6411
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0028"
                     /evalue="7.40E-09"
                     /label="NRPS-E6"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2137"
                     /protein_start="2116"
                     /score="27.9"
                     /tool="antismash"
                     /translation="VKEELRSVPRRGVGYGVLRWL"
     CDS_motif       6445..6465
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0029"
                     /evalue="4.30E-01"
                     /label="NRPS-E7"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2155"
                     /protein_start="2148"
                     /score="4.0"
                     /tool="antismash"
                     /translation="VLFNYLG"
     aSDomain        6799..7671
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS45820_Condensation_DCL.2
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="3.60E-101"
                     /label="C8D88_RS45820_Condensation_DCL.2"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2557"
                     /protein_start="2266"
                     /score="330.1"
                     /specificity="C activity: inactive"
                     /specificity="Active site motif: YQGLCDG"
                     /tool="antismash"
                     /translation="DVYRLAPVQSGMLFGVAGSPVDGLYWGQGVYDLAGPIDAERLADA
                     WRSVIARHAALRSGFVWEGVSEPVQIVLADVNVPLEQRDWSGLDDAAQQEQLQALLASD
                     RALGFDLAVPPLTRLYLVDRGEDRLWLVWGLYQGLCDGWSLPVVMDEVSATYQGQSLEP
                     VRSYRDFIAWLGRRDPSESEGFWRTYLDGFEAPTPLPVDRLASSHYDQDRRRMRLDETV
                     TAKLVELARRERVTLSTVVQAAWALLLSTYSGDDDVVFGLTVSGRPAELAGVESMVGLF
                     INTLPVRAAV"
     CDS_motif       6805..6840
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0030"
                     /evalue="1.90E-02"
                     /label="C1_dual_004-017"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2280"
                     /protein_start="2268"
                     /score="8.3"
                     /tool="antismash"
                     /translation="YRLAPVQSGMLF"
     CDS_motif       6868..6984
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0031"
                     /evalue="2.40E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2328"
                     /protein_start="2289"
                     /score="48.8"
                     /tool="antismash"
                     /translation="LYWGQGVYDLAGPIDAERLADAWRSVIARHAALRSGFVW"
     CDS_motif       7213..7266
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0032"
                     /evalue="6.30E-06"
                     /label="C3_DCL_135-156"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2422"
                     /protein_start="2404"
                     /score="18.8"
                     /tool="antismash"
                     /translation="LCDGWSLPVVMDEVSATY"
     CDS_motif       7297..7332
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0033"
                     /evalue="7.40E-02"
                     /label="C4_DCL_171-183"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2444"
                     /protein_start="2432"
                     /score="6.5"
                     /tool="antismash"
                     /translation="YRDFIAWLGRRD"
     CDS_motif       7498..7557
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0034"
                     /evalue="5.50E+00"
                     /label="Cy4"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2519"
                     /protein_start="2499"
                     /score="0.5"
                     /tool="antismash"
                     /translation="RVTLSTVVQAAWALLLSTYS"
     CDS_motif       7567..7662
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0035"
                     /evalue="1.80E-21"
                     /label="C5_DCL_263-294"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2554"
                     /protein_start="2522"
                     /score="68.6"
                     /tool="antismash"
                     /translation="DVVFGLTVSGRPAELAGVESMVGLFINTLPVR"
     CDS_motif       7711..7833
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0036"
                     /evalue="4.50E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2611"
                     /protein_start="2570"
                     /score="64.1"
                     /tool="antismash"
                     /translation="QDNQVALQRFEYTPLVDVQRWSAVPHGRALFDSIVVFGNYP"
     CDS_motif       8332..8367
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS45820_0037"
                     /evalue="2.70E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="C8D88_RS45820"
                     /protein_end="2789"
                     /protein_start="2777"
                     /score="8.3"
                     /tool="antismash"
                     /translation="GVLRSGGVYVPV"
ORIGIN
        1 gagatcgtgc cgggcatgct cctgcgcgac ctggccgcgc actgccgtga ggccgggccg
       61 gtcaagtcgc tgcgcctggt catctccggc accgacatgt ggacgcacga cgcgctcacc
      121 ggagcggtcg ccgatgtggc gccggatgcc ttggcgggca acgtgttcgg tgtgaccgag
      181 gccgcgatcg actcgatctt ccacccggtc ggcgaggatc acccggcggc ggtggtgccg
      241 atcggcaagc cgttggccgg tgcccaggcg ttcgtggtgg acgggacgct gcggccggtg
      301 ccggtgggtg ttcccggtga gttgctggtc ggcggtggcg gtgtggcgcg cgggtatgcc
      361 ggccgtccgg atctgacggc ggcacggttc gtgcccgatg tgttcggtgg atccggcggg
      421 cggttgtacc gcaccggtga ccgggcccgg tggcgtgccg acggtgtgct cgagttcctg
      481 ggccgggtcg acgagcaggt gaagatccgc ggctatcggg tcgagcccgg tgaggtcgag
      541 gtcgtcatcg gtgaccaccc cggcgtgcgt gatgtcgttg tggtggctcg ggatggtggc
      601 ccgcacggcg gcaagcggct cgtcgcttac gtggtggccg agtccgagga cgtcagtggt
      661 tcggtgctgc gtgcgtggtt gcgtgagcgc gttccggatt acctggtgcc gtcggtgttc
      721 gtggccttgg accggttgcc gctgacgccg aacgggaagg tcgaccgtcg cgggttgccc
      781 gagcctgagc cggaggcagt cgcggagacc tgtgtcgcgc cccggaccgc cgtcgaggaa
      841 acgctggcgg cggtgtggag tggcgtgctc ggtgtcgggc gcgtcggcgt gcacgacaac
      901 ttcttcgagc tgggcggcga ctcgatcctg agcctgcaga tcgtcgcccg tgtgcgggcg
      961 gccggtctgg gcgtcgatgt ggcggacgtg ttcgcccatc agaccatcgc agagctcgcc
     1021 ctcgccgtgc gcgacacccc tgcggtctcc tcggcggagc agggcgtggt caacggtccg
     1081 gtgccgttca cgccgattca gcggtggttc ctggcgcagg acatcccgga ccgggatcac
     1141 tggaactggt cgggtgtgtt cgagctggcg ccgggcaccg accctgatcg tctcgtgtcg
     1201 gcgctcaacg ctgtggtggc gcaccacgac gcgttgcgca tccggttcac gccggagggc
     1261 cagtacaacg ccggtatcga agctgccgac ttgcgtgtcg ttgctgtgca cgacgacgaa
     1321 gtgcctgcgg agatgacggc ggcccagaag tcgttgcgtc tggccgatgg tccgctcatc
     1381 gccgccgtgc tcttcgaccg cggtgacgag cccgcgtggc tgggtctgac cgtccatcac
     1441 ctggtgatgg atggtgtgtc gtggaacgtg ttgctggagg atctcgacac cgcgtaccgc
     1501 tcagaggcgt tggggcccaa gacgtcctcg ttccagcagt gggccgagca cctgctggag
     1561 ctggaggtcg gcggggaacg ggagcactgg gtcgcggcga cgtcggacgt ggtcgcgctg
     1621 ccggtcgacc aggacggacc gaacaccgag gtgtccggtg ccgtggtgcg cacctggctg
     1681 gacgccggca ccaccgccgc actgttcggc gaggcccaca aggcttatcg gacacaggcc
     1741 aacgacctgt tgctcgccgc gttggcgaac gtcctggggg agtgggccgg caccgaccac
     1801 atcacggtcg acctggagag ccacggccgt gagggcctgg acctgtcacg cacggtcggt
     1861 tggttcacat cgatcttccc ggtccggttg agccgacaca ccgatccggg cgcgacggtg
     1921 aagacggtga aggaacagct gcgggcggtg ccgcgccgtg gtgtcggcta tggcgtgttg
     1981 cggtggctgc ggggtgagtt ggccgatgcg ccggatcgtc cggtgctgtt caactacctc
     2041 ggcgccttcg acgcggtcga ctccgtcggc ctgatccgcc gggagcttcc ggccgagctg
     2101 gccggtccga tgcagggacc cggcgggacc agggcctacc cgctgcagct cgaagtcgtc
     2161 cgcgcggacg acggccggct gcggatcgac tggctgcaca gcacgaacgt tcatctcccc
     2221 ggcaccgtcg agcgggtcgc tgcccgttat gtcgaggcgt tgcgcgaact ggtgacgcac
     2281 tgccagtcgg gagtcgcggg cttcacgccg tcggacttcc ccttggcgtc gttgacgcag
     2341 ggcgaggtcg acgggctcgc ggagcgttat ccgctggtgg atgtgtaccg gttggcgccg
     2401 gtgcagtccg gcatgttgtt cggcgtcgtc ggttcgcccg tcgacggtct gtactggggc
     2461 cagggcgtct acgacatcgc cggtcctgtc gacgccgagc gactggcacg ggcgtggcgc
     2521 gaggtgatcg gccggcacgc cgcgctgcgg agcgggttcg tgtgggaagg cgtcagcgag
     2581 ccggtgcagg tcgtcctggc ggacgtcgag gttccgctgc agctgcgcga ctggtccgat
     2641 ctcgacgggg acacccagca gtcacggctg cgcgagttgc tggccgagga ccgggcgctg
     2701 ggcttcgacc tggcggcgcc gccgttgacg cggctgtacc tggtggaccg cggcaaaggt
     2761 cgcctttggc tggtgtgggg gctgtaccag ggtttgtgcg acgggtggag ccttcccgta
     2821 gtggtggacg aggtgttcgc cgcctacgac ggcgagaccc tggctccggc gcggccgtac
     2881 cgggagttca tcggctggct ggacgggcgt gatccggacg agtccgaggg tttctggcgc
     2941 acctacctgg acgggttcga ggcgcccact ccgttgcccg tggatcggct ggcggcgagc
     3001 cattacgcac aggatcgccg caagacgatg ctggacgagg gcgtcaccac caggctggtg
     3061 gagctggcgc ggcgtgagcg cgtgacgttg tcgacggtgg tgcaggcggc gtgggccaag
     3121 gtgctctcgg cgtcgtcggg cgaggacgac gtggtgttcg ggctgacggt gtcgggtcgt
     3181 ccggctgagc tggccggggt ggagtcgatg gtcggcttgt tcatcaacac gttgcccgtg
     3241 cgggctgtgg tgccggtcga cacgccgttt gcgtcgtggt tgcgtgagct gcaggacaac
     3301 caggtcgcgc tgcaacggtt cgagtacacg ccactggtgg atgtgcagcg gtggtcggct
     3361 gttccgggtg gccgcgccct tttcgactcc atcgtcgtgt tcggcaacta cccgcaccag
     3421 gacctgccgg acgacctggc cgccggctac gccaccgtcg actcggtgga gcagggcaac
     3481 tacccgctca ccttcgcggt cgacctggaa cgccgcctgc gcatcgaggc tgagttctcc
     3541 acggccgcct tcgaggcggt cacggtcgag cggatcctcg accagctggt ggtcgtgctc
     3601 accgcggtgg cggaacggcc ggagctcgcg gtcgtggacg tgccgttgca gcgcccggag
     3661 caggcggcgc agctcgtggc gtggggcgag accccggttc cggtcgccga ggcgtccgtc
     3721 cccgagctga tccacagctg ggcggacagt gccgaggttg ccgtggtgtg cggcgacgag
     3781 cgcctgacgt tcgccgagct ggacgcccgc tccgctggtc tggcggcacg gctgcggcag
     3841 gccggggtga cggtggagtc gccggtcgcg gtgttggtgc cgcgtgggat tgagctggcg
     3901 gtggcgttcc agggcgtgtt gcgcagtagt ggcgtgtatg tgccgatcaa tcccggtctg
     3961 cccgccgaac gcctcgcgtt cctcctcgag gacgttggtg cggtcgccgc ggtcacgact
     4021 tcggccctgg ccggtgagct ggccgcgttc agcggcgaag tgctggtgat ggacgacacg
     4081 gtcctcgatg cgctgtcggt gcacatgaac cctgatgcgt tggcgtacat cgcttacacg
     4141 tcgggttcga ccggccgtcc caagggtgtg gcggtgacgc atcgcgcgtt gtcgtcctat
     4201 gtggctggtt ggcgtgatgg cctgcgcgcg ttgggtgggc cgggcacggt gttgtcgatg
     4261 tcgggtccgg gtttcgacgt gtcgatcggt gacatgactc gtgccctggc gtttggccag
     4321 acggtggtgt tcctgccgca cgacgagcat gtgtcggtgg agtcgctgca cgccacgttg
     4381 gtcgagcacc agatcgaagt ggccgagatc gttcccggca tgctcctgcg cgatctggcg
     4441 gcgcactgcc gggtggcggg gccggtcgag agtctgcggt tggtgatctc gggtacggac
     4501 atgtggacgc acgacgcgct cacgagtgcg gtggctgaag tggcgccgaa tgcggtgccg
     4561 ggcaacgtgt tcggtgtgac cgaggcggcc atcgactcga tcttccacgc cgtgatcgag
     4621 gacgaccccg cggcagtggt gcccatcggt actccgctgg ccggtgcccg cgctgtggtg
     4681 gtcgattcgg cgatgcggcc cgttcccatc ggtgttccgg gtgagctgtt ggtcggtggt
     4741 gccggtgtgg cgcgtggcta cctgggccgt cccggcctga ccgccacgag gttcgttccc
     4801 gacttgttcg gtgcggccgg tggccggctc taccggaccg gtgaccgggc gcggtggcgt
     4861 gcggacggca cgatcgagtt cctcggccgg gtcgatgagc aggtgaagat ccgcggctac
     4921 cgcgtcgagc ccggcgaggt cgaggtcgtc atcggtgacc accccggcgt gcgtgatgtc
     4981 gtcgtggtgg cgcgggatgg cggtccgcac ggcggcaagc ggctcgtcgc ttatgtcgtg
     5041 gccgagtccg aggacgtcag cggttcggtg ctgcgtgcgt ggttgcgaga acgcgttccg
     5101 gactaccttg tgccgtctgt gttcgtggcg ctggaacggt tgccgctgac gccgaacggc
     5161 aaggttgatc gaagaggcct tccccaccct gagcccgaga cagccggtga ggcgtatgtc
     5221 gcaccgcgga ccgctgccga agagaccctc gcggccgtgt ggagtggcgt gctcggtgtc
     5281 gagcgcgtcg gcgtgcacga caacttcttc gagctgggcg gggattcgat cctgagcctg
     5341 cagatcgtcg ctcgcgttcg tgccgctggt ctgggtgtcg atgtggcgga cgtgttcgcc
     5401 caccagacgg tcgccgagct ggcgggcgtc gtgcgcgaca cgccctcggt gaccctggct
     5461 gaccaggggg tggtgaccgg ccctgttccg ctgacgccga tccagcactg gttcctggcc
     5521 gaggacatcc cgaaccggga ccactggaac tggtccggca tgttcgaact ggcaccgggt
     5581 accgatcccg atcgtctgag ccgggcgctc gatgtccttg tcgcgcacca cgatgcgttg
     5641 cggatccggc tcgacgccaa tgggcagtac aacgcaccgg tcgacggcgg cagcgtgttg
     5701 cgcgtcgtcg aggttgccga cgacgaggct gtggtggcgc acatgaccgc cgcgcagacg
     5761 tccttgcgtc tggtcgatgg tccgctcatc gccgccgtgt tcttcgatcg tggttcgcag
     5821 cctgcgtggc tcggtctgac cgttcaccac ctggtgatgg acggggtgtc gtggaacgtg
     5881 ttgctggagg acctcgacac ggcttgtgca ggccgggcgc tcgggccgaa gacgacgtcg
     5941 ttccagcaat gggccgaggt cctgcgggag ctggacgcgc aggcggagcg ggagacctgg
     6001 ctggcccaga ccgcggacgt ggtggcactg ccgcaggacc gccaagggct caacaccgag
     6061 acttcggccg gtgtcgtgcg gtcgtggctc gaccccgaga ccaccgccgc gctgctgggc
     6121 gacgctcacc gcgcctaccg cacccagggc aacgacctgc tgctcgccgc tctcgcccag
     6181 gcgctggggg agtgggcggg taccggccac gtgacggtgg acctggaaag ccacggccgt
     6241 gaggcggtgg cggacggcgt cgacctgtcg cgcaccgtcg ggtacttcac gtcgatcttc
     6301 ccggtgcgcc tcacccacga ggacgatcca gcggcggcga tcaaggcggt caaggaggag
     6361 ctgcgatcag tgccgcgccg tggtgtcggc tatggcgtgt tgcgctggct gcagaacgac
     6421 ctggccgatg ctcccgatcg gccggtgttg ttcaactacc tgggtgcttt cgacgccgtc
     6481 gactcgctcg gcctgatccg ccgggagctc cccgccgagc tggccggccc gagcgagggc
     6541 tccggcggga cccgttcgca cgtcctgcag atcgaagccc agcaggacac cgacggacgg
     6601 ctgcgggtcg actggcactt cagccacaac ctgcacgaca ccgtcaccgt cgaacgggtt
     6661 gcggctcggt acgtcgaggc gttgcgtggg ttggtcgggc actgccggtc ggctggtggg
     6721 ttcacgccgt cggacttccc gttggcgtcg ttgacgcagg ttgaggtgga cgggctggcg
     6781 gagcgttatc cgctggtgga tgtgtaccgg ttggcgccgg tgcagtcggg catgttgttc
     6841 ggtgtcgcgg gttccccggt cgacgggctc tactggggac agggcgtcta cgacctcgcc
     6901 gggccgatcg acgcggagcg gcttgccgat gcctggcggt cggtgatcgc ccggcacgcc
     6961 gcgttgcgca gcgggttcgt gtgggagggc gtcagcgagc cggtgcagat cgtgctcgcc
     7021 gacgttaatg tcccgcttga gcagcgggac tggtccggcc tcgacgacgc ggctcagcag
     7081 gagcaattgc aggcgctcct ggcgtccgat cgcgcgctgg gcttcgatct cgccgtgccg
     7141 ccgttgacgc ggctgtacct ggtcgatcgc ggcgaggacc ggctgtggct ggtgtggggc
     7201 ttgtaccaag gcctgtgcga cgggtggagc ctgcccgtcg tgatggacga ggtgtccgcc
     7261 acctaccagg gccagtcgct tgagcccgtc cggtcctacc gggacttcat cgcgtggctg
     7321 ggccggcgtg acccgtccga gtccgagggc ttctggcgca cctacctgga cggcttcgag
     7381 gcccccacgc cacttccggt cgatcggctg gcgagcagcc actacgacca ggaccgccgc
     7441 cggatgcgcc tggacgagac cgtcacggcc aagctggtcg agctggcccg ccgcgagcgc
     7501 gtgacgctgt cgacggtcgt gcaggcggcg tgggcactgc tgctgtcgac gtattcgggt
     7561 gacgacgacg tggtgttcgg cctgacagtc tcgggccgtc ctgctgagct ggccggggtc
     7621 gagtcgatgg tcggcctgtt catcaacacg ctgcccgtgc gggcagcggt gccgggcgac
     7681 acgtcgttcg ccgagtggtt gccttcgctg caggacaacc aggttgcgct gcaacggttc
     7741 gagtacacgc cgttggtgga cgtgcagcgg tggtcggccg ttccgcacgg tcgtgcgttg
     7801 ttcgattcca tcgtggtgtt cggcaactat ccgcaggaag agttgccgga agacctgagt
     7861 ggcttgcagg ccgccgactc ggtcgagcag ggcaactacc cgctcacctt cgccgtcgac
     7921 ctcgaacgca cgctgcgtgt ggaggcggag ttctcgacgg cggcgttcga cgcggtcacg
     7981 gtcgagcgga tcctcgacca gctcgctgtt gtgctcaccg cggtcgcgga acggcctgag
     8041 ctggcggcgc gggacgtgcc gttgcagcgt cccgagcagg ctgccgaatt ggtggcgtgg
     8101 ggtgccaccc cggtgcctgt tgccgagcgg ccggtgccgg atctgatcga cgactgggcg
     8161 cggacctcgg ccgagatcgc cgtgatctgc ggggacgagc ggctcacgtt cgccgagctg
     8221 ggcacgcggg ccgatgcgct ggctgctcgg cttcagcagg ccggggtgac cgtggcgtcg
     8281 ccggtggcgg tgttggtgcc gcgtgggatc gagctggcgg tggcgttcca gggtgtgttg
     8341 cgcagtggtg gcgtgtatgt gccggtcaac c
//
