LOCUS       NZ_QGHB01000011        22178 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Lentzea atacamensis strain DSM 45480 Ga0215650_111, whole genome
            shotgun sequence.
ACCESSION   NZ_QGHB01000011
VERSION     NZ_QGHB01000011.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea atacamensis
  ORGANISM  Lentzea atacamensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 340736)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 340736)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Expected Final Version            :: No
            Genome Coverage                   :: 90.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003148865.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:35:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,333
            CDSs (total)                      :: 9,254
            Genes (coding)                    :: 9,110
            CDSs (with protein)               :: 9,110
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 6 (5S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 32 of 144
            Pseudo Genes (incomplete)         :: 121 of 144
            Pseudo Genes (internal stop)      :: 2 of 144
            Pseudo Genes (multiple problems)  :: 11 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:50:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 231780
            Orig. end                         :: 253958
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QGHB01000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22178
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22178
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22178
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12178](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12178
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            696..1094
                     /locus_tag="C8D88_RS33490"
                     /old_locus_tag="C8D88_111232"
     CDS             696..1094
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501899.1"
                     /locus_tag="C8D88_RS33490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111232"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_109639973.1"
                     /transl_table=11
                     /translation="MSTQVDQFGWLVTNFTERTPGIEHAVVISADGLVLISSSRLPAHV
                     APQFAAIVAGVVSLAESACQCFAGESVVRTVVQMDRGVMLLMSISDGSVLAVLASSSCD
                     VSQVAYEMTVVVRQVGQLLTPELRAELA"
     gene            1091..1606
                     /locus_tag="C8D88_RS33495"
                     /old_locus_tag="C8D88_111233"
     CDS             1091..1606
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010305141.1"
                     /locus_tag="C8D88_RS33495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111233"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_109639974.1"
                     /transl_table=11
                     /translation="MNREPDEQVNFGDLISGFSFDSERIRKRGKKKATRAAEPPPEPDP
                     YATLPFDVPPLPSIESSASIVRAYAWTGGRTTSEVHLEIETLVSVNEFSATAVRPEHQD
                     VLALCHSPRSVAEIAALRGLPLGVTKVLLGDMAAHGLIDVHRTASSYGGDRPDGALLER
                     VLAGLRRL"
     gene            1665..2252
                     /locus_tag="C8D88_RS33500"
                     /old_locus_tag="C8D88_111234"
     CDS             1665..2252
                     /EC_number="1.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005166896.1"
                     /locus_tag="C8D88_RS33500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111234"
                     /product="nitroreductase family protein"
                     /protein_id="WP_109639975.1"
                     /sec_met_domain="PF00881 (E-value: 2.1e-19, bitscore: 64.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFQDVVRRRRMVRKFTGEPVSDESIQRIMRNAVRGPSAGFSQGQ
                     GFLVLQGESLKRLSEMFEWWGGEGAKSAPVVVIPFSAKDVYLDRYAQADKGWTDRDENR
                     WPVPYWDIDTGMAALLILQTAVDEGLGAVFFGTDKETWPELRAAFGVPDSYVPIGMIAI
                     GHPAEEGISEGASPRTRKRTPFEEMVHWGQWK"
     gene            2243..5179
                     /locus_tag="C8D88_RS33505"
                     /old_locus_tag="C8D88_111235"
     CDS             2243..5179
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="C8D88_RS33505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111235"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_170155182.1"
                     /transl_table=11
                     /translation="MEVRSFGLLGPLDVVLDGHHVHVPSGKRRVILAALLLRPGQVVGV
                     DELVELTGGSRNALQTAVGRLREDLGRPELVQTRPGGYLLDVRPDEVDVHRFGLLEPRE
                     ALKLWRGRPFADIGSDALERDHVPALTEQYLATLEARIDQDLKHGRHEQLVPELRTLTG
                     QHPARERLWAQLIVALHRCDRQTEALRAYDDIRTRLTEELGLDPGRDLQQAHQQVLTAD
                     NRPRARNDLPGDIPDFAGRADDLDEILAAVPSGCVAITAIDGMAGIGKTTLAVRAAHRL
                     APKFPDAQLFVDLHSYTEGAEPRTPSDALLALLTALGVPAQDIPDGLDARAARWRAEMA
                     HRKALVVLDNAGSAAQVRPLLPGTGLVLVTSRRRLVDLDAAYPVSLDVLSEEDSLNLLA
                     RIVGQKADLDAAREIVRLCGYLPLAVRIVGARWRTRPAWSAQDLVRRLTQQRLIELKAG
                     ERSVAGAFALSYQQLTADQQRLFRRLGLHTGEDWDVHLAAAVAGTTRAEAERLLDELLD
                     VHLVQQQENGRYRFHDLLADHAKASVEPDEKDEAVVRILDHYLHGAATSAQRIAPGRPE
                     IHSTVTYEQIDPPVFATPVEALAWQEAERRNLRAAVYLAAYEGHYRYAWQLPHHFAHFL
                     LLRGSGRERVEVQSVALAAAHHLGDLQARAEALRGLGSAYLGQENYEKAAEHLHEALDL
                     MRQIGDVRGEASTLGLLGMVAREQREFDKAMEHYQRGLVLMRQVGAPTGEADALEHIGI
                     LHAERGEYDEALTHLEHALPLLQSRGDVRAYAGVLHDLAYAHFGMFNDKESRSCAERSL
                     AAYRESGDRRGESIAVAEFAYWRYETGDFAAVREMVREVRRLCRAYMNLPDDHAVLAAM
                     EEIRDHIGQVAMLVALSLAAQVDGRLTEAIGHTQRCLAVVSSTSRWWSRYKVLGQLSTL
                     HLALGDRETAVRYGEEAVAAAEDLRQPRARAVAKRILATATAPAAPAS"
     gene            5463..8615
                     /locus_tag="C8D88_RS33510"
                     /old_locus_tag="C8D88_111237"
     CDS             5463..8615
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="C8D88_RS33510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111237"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_146231763.1"
                     /transl_table=11
                     /translation="MDFGILGPIQARDSGVRLELGGVRGQKVLAALLLAPNRVVPLTQL
                     VDVVWDGEPPSTGKHQIQKSVGDLRSALGVPGLIVTDGPGYRIALGSATLDVLTFERHV
                     ATAQTVEPAEAVRLLRTALSLWRGPALAGLDGQVLRVEAERLDERRIAVAQQCFGLQLE
                     LGQHEQVITELSALVAANPFREQLVEQLMLALYRSNRQADALELYDRTRRLLADELGVD
                     PGRSLRAAHQAILNQDSESTHVSPKAPAQLPADLARFTGRESYLDALDAGLSASTVVIT
                     SIAGTAGVGKTALAVHWAHRVRDKFPDGQLYLNLRGYDDAPATTPAEALTQLMRGLGVE
                     PDQIPREVDEQASTYRSILSTRRVLILLDNAASEDQVRPLLPGTPGCAVIVTSRNDLRG
                     LTALDDARRVELDLLTADEAHALITRVLGAARADTEPEAVADLAALCGYLPLAIRIAAA
                     NLACRPHDRIADAVADLAQGNRLAQLSISGDRRAAVTAAFELSLKSLPDEASLLFQRLG
                     LLPRTDFTAHTASVLMGVDDVRPLISLLESASLIEPHTRGRFRVHDLLHLYARELVTSD
                     EDAGQAGLRLLDHYLHTTDAALDVLAPEMYRLCRDGTSALSFGSKEAALSWLDAEGEAV
                     AICALRAEPPRYRWELADSLRRMWYLRQQFDRWHETASAGLLAAEQENDLRGQASMHLS
                     LGTMHCELDGRQGIGHLETAFALYEEADDRAGQFHCLNNLSVVHLTLGRTQEAIGLLRD
                     ALPLVDDNLRLSAVVHLNLGVATAQTGRLTESLAHYEQARELLRQAGGSVSDTLVEFAL
                     AELHVVLGDPVRAREHAVRGARMAEESGSHAWWYVLQSVEAKIDRDTGRTQRALTRALA
                     LVDEAEEGAAELYVLLGLVIAGSAYHRLGRLREAIEALRRGLRLAGSLGRVDNETEYLI
                     DLARALQAAGDERSAGELAERALDQATTFGFAMQRGRALATLALLSLKAGDAERARGFA
                     AEAVEVQRETGFVLGQAESLLVLARVADHPAALQETRAIVARLTGPHGGDPAGVLCETD
                     VG"
     misc_feature    9000..9018
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.7"
                     /tool="antismash"
     misc_feature    9053..9067
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.89"
                     /tool="antismash"
     misc_feature    complement(9063..9077)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.8"
                     /tool="antismash"
     misc_feature    9067..9083
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.11"
                     /tool="antismash"
     misc_feature    complement(9218..9234)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.57"
                     /tool="antismash"
     misc_feature    complement(9281..9296)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.87"
                     /tool="antismash"
     gene            9311..9859
                     /locus_tag="C8D88_RS33515"
                     /old_locus_tag="C8D88_111239"
     CDS             9311..9859
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098743.1"
                     /locus_tag="C8D88_RS33515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111239"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_109640093.1"
                     /transl_table=11
                     /translation="MGGVPTFPHGRPLTWADLEAMPDDGHRFELVDGVLVMSPSPRPVH
                     QRVVARLLVTLTAVCPPELEVLPAPVDVVLADDTVFIPDLVVGRREQFTKQALMGPPVL
                     AVEVLSPRTRHVDLELKRAKFQEVGCENYWLIDYDGPWLRCLHLENGVYVEQARSEGEE
                     IIELQYPFAVKLSAQSLVR"
     gene            10001..12178
                     /locus_tag="C8D88_RS33520"
                     /old_locus_tag="C8D88_111240"
     CDS             10001..12178
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012783597.1"
                     /locus_tag="C8D88_RS33520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111240"
                     /product="terpene synthase family protein"
                     /protein_id="WP_109640094.1"
                     /sec_met_domain="T1TS (E-value: 1.7e-74, bitscore: 246.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPFQLPEFYTPHPARLNPNLERARVHTRAWAHEMDMIDVPQHGT
                     VVWTDDDLESHDYALLCAYTHPDCDGETLDLITDWYVWVFYFDDHFVELYKRNPDIKGA
                     QAYLDRLPLFMPVNGVITATPANPVEKGLADLWRRTVPSHSLDWRERFASNTKHLLDES
                     MWELHNISAHRLSNPIEYIEMRRKVGGAPWSANLVEHAVGLEVPAQIALSRPIGVLRDT
                     FSDAVHLRNDLFSYEREVLDEGELSNSVLVFEKFLDLPTQDAAEAVNDLLTSRLHQFEH
                     TALTEVPLLLDEHAIDPIGRAAVLGYVKGLQDWQAGGHEWHLRSSRYMNKGLRTQPGTS
                     AADVLGSYARTMPQRLKQFTATPKIVEPYPRPTYDIPFALGMAPHLDQCREEVIAWSEE
                     VGFHGEGIWDEAKNRRFDLALASVCMDPDGTPSELFLSAAWLTWGTYGDDFYPWVFGRL
                     KDLAGLKSQTARLKLCMPLDLVPTIVPVNAVERSLADLWQKTAAPMSPEFRSTFRKAVD
                     AMLDAWAWEVINIQQNRIPDPVDYLEMRRSTFGSELTTSLSRFSHSTTVPPEIWGTRVV
                     QTMERSAMDYTFMVNDTISYLKEIQYEGEVHNMVRVVENFLGVSQPRAFEITFKLMDAR
                     LGQFVQAVDVDLPKLFEDLSLDSATRASLTRYADELKDWIVGVTHWHVETSRYHEEEIR
                     TPVNAHLLAGAFNRGPSGLGTSAARLVAVKR"
     gene            12252..13340
                     /locus_tag="C8D88_RS33525"
                     /old_locus_tag="C8D88_111241"
     CDS             12252..13340
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017985409.1"
                     /locus_tag="C8D88_RS33525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111241"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_109639978.1"
                     /transl_table=11
                     /translation="MKNVLISGASIGGPALAYWLRHHGFAVTVVERARGLRPGGQAIDV
                     RGPALEVIERMGLGDRLRSLSTNMRGMTMLDAEGNELFSSTTHTLSGGELASPDVELLR
                     DDLATMLFDAAEGVEYLFDDTITAIDGTGVTFEKAAPRDFDVIVGADGLHSNVRRLVFG
                     PESEFVSHLGMNLAVFTAPNFLNLDHWQIFQQDGEVGGGVMSARANAECRVYMGFNGEA
                     DVDYRDIEAQRRLIAEKFADAGWEWQNALKHMWEAPDFHFDSMSQIRMETWSRGNVVLL
                     GDAGYCGSPLSGQGTSMALVGAYVLAGELRDNPATAFQRYEEILRPYVTANQDMALKNR
                     ENGGAPSEEFADVVNSLQLPAY"
     gene            13435..15162
                     /locus_tag="C8D88_RS33530"
                     /old_locus_tag="C8D88_111242"
     CDS             13435..15162
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645687.1"
                     /locus_tag="C8D88_RS33530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111242"
                     /product="family 20 glycosylhydrolase"
                     /protein_id="WP_109639979.1"
                     /transl_table=11
                     /translation="MRTRVLAAVIAVTAALSVSAQSQAAEPLQSLVPVPVSVQARAGVT
                     HTLTAATKIYTAPAARDVGNFLAGVLRPSTGYALPVSDTTGTPADGISLLLSGAPGTVG
                     QQGYQLDVAAGAVVLRANTPEGLFAGVQTLRQMLPAAVESATVKPGPWTVPGALIVDHP
                     RFAYRGAMLDVARHFHPVASVKRYLDQLALYKINYFHLHLSDDQGWRIMIDSWPRLATY
                     GGSTQVGGGAGGYFTKAQYSEIVQYAAARRITVIPEIDMPGHTNAALASYAELNCNGQA
                     PPLRTDIEVGYSSLCVNKDITYQFIDDVVREIAALTPGPYFHIGGDEAHATSDADYQAF
                     MNRALPIVKKYGKTVLGWHEFVKTTTDTTAIPQYWGTTTSNATVQAAAARGNKVVMSPA
                     NKAYLDMKYNSSTPLGLSWAGFIEVQDAYNWNPGTHLSGVPESAVRGVEAPLWTETIVT
                     SRDIEFMAFPRLPVLAELGWSPWSTHNWDQFKVRLGNQAPRWTTMGINFYRSAQVPWDT
                     GGPAPGPCPQPAWERSKVYTGGNVVSHNGHKWTAQWWTQGEEPGTTGQWGVWRDGGVC"
     gene            15187..15372
                     /locus_tag="C8D88_RS33535"
                     /old_locus_tag="C8D88_111243"
     CDS             15187..15372
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D88_RS33535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D88_111243"
                     /product="hypothetical protein"
                     /protein_id="WP_109639980.1"
                     /transl_table=11
                     /translation="MTDPEEAEEFAEEVGVDPTPQEVDEYRDMTEPGEWRADEKMGPDG
                     APAPQDGDDPTGGSGA"
     gene            15420..16325
                     /locus_tag="C8D88_RS33540"
                     /old_locus_tag="C8D88_111244"
     CDS             15420..16325
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016698022.1"
                     /locus_tag="C8D88_RS33540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111244"
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="WP_109639981.1"
                     /transl_table=11
                     /translation="MDARVAVFAPSPQLTVTVEDLDGEPDVHLHAGGQGFWQSRMIASL
                     GVEAVVCAAFGGETGRVLRTLLEGEHIDLRAREVAARNGSYVHDRRDGERSEMVEMLPD
                     ALSRHELDDLYESMLVEGIRAGTAVLSGPSDDRVLPHETYFRLTSDLTKNDCRVIVDLA
                     GERLAEAVRGGPHVVKVSHEELGEEELPELVRACRKIASSGVHGVVVSRADEPALALLD
                     EQLYLVRMPRLEPVDTRGAGDSMTAGISAGLALGMSLDDAVKLGAAAGAVNVTRHGLGS
                     GGGEAVRELSKRVELEPIEE"
     gene            16330..17085
                     /gene="surE"
                     /locus_tag="C8D88_RS33545"
                     /old_locus_tag="C8D88_111245"
     CDS             16330..17085
                     /EC_number="3.1.3.5"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004309 - exopolyphosphatase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008254 - 3'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0106411 - XMP 5'-nucleosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="surE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803656.1"
                     /locus_tag="C8D88_RS33545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111245"
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="WP_109639982.1"
                     /transl_table=11
                     /translation="MRALITNDDGIDSPGLLTLASAAVSCGLDVVVAAPATQSSGTSAS
                     VAAASDTGRVVSERRTLPGLDAEAYAVAAHPALITLIACRGGFGGKPDLVLSGVNLGAN
                     VGRAILHSGTVGAALTGQLNDVSSLAVSLDVGLDGPEPLWDKADEVVRAVLPVLLEMPA
                     ATVLSLNVPNIVDVQGIRWAKLARFGSVQSRVDEVDENEIELVTVYSEESLVPGTDSAL
                     LASGYATLTPLNSVSEDVSSPRPSPAWPV"
     gene            complement(17048..17377)
                     /locus_tag="C8D88_RS33550"
                     /old_locus_tag="C8D88_111246"
     CDS             complement(17048..17377)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D88_RS33550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D88_111246"
                     /product="hypothetical protein"
                     /protein_id="WP_109639983.1"
                     /transl_table=11
                     /translation="MALLSNELEFTRPQILTLTAGVLQLALGWFDVFGLDPDYHVIQIG
                     VGALGVVMAWRHDLARMYGILLLLSFGMLAFSLEDVTTEGFLEVRTALIGLVITLARPG
                     KDAAS"
     gene            complement(17386..17781)
                     /locus_tag="C8D88_RS33555"
                     /old_locus_tag="C8D88_111247"
     CDS             complement(17386..17781)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800804.1"
                     /locus_tag="C8D88_RS33555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111247"
                     /product="DUF5313 family protein"
                     /protein_id="WP_109639984.1"
                     /transl_table=11
                     /translation="MNPALKLWYYAGGRVPQKYREFVYADVTGPKWLVRFTVRSLVQVT
                     PLTTAITLALVFGLGSPWPLAIACGALGFVVGLYFALSYAPESVDYRLTKYGYPRGSAT
                     SGRRERNAARDRERQAKYDAVWRRFEG"
     gene            complement(17778..18227)
                     /locus_tag="C8D88_RS48790"
     CDS             complement(17778..18227)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946288.1"
                     /locus_tag="C8D88_RS48790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_109640095.1"
                     /transl_table=11
                     /translation="MISTPSIPENPLELERQVCFALAVASRTVIAVYRPILEPLNLTHP
                     QYLVMLALWERSPRTVKDLSTVLQLDPGTLSPLLKRLEAIGYIERQRDKSDERALALTL
                     TEQGRELRTEALKIPFKVVEQLDMTFEELAQLNEVLHKVIAKATR"
     misc_feature    18227..18245
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 21.38"
                     /tool="antismash"
     gene            complement(<18363..18698)
                     /locus_tag="C8D88_RS49500"
                     /pseudo=""
     CDS             complement(<18363..18698)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014910.5"
                     /locus_tag="C8D88_RS49500"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTTVVRAMPVIYPVAGLQHPVAGRTGRGPGTSRAQSRPRSARSVM
                     TTLDLPGLLTDPVTLENLSHDEAEWAPAGAPAAAFHPQSTEDVQKAAFAEIIDQDVDLG
                     GIVTGEHG"
     gene            18676..19503
                     /locus_tag="C8D88_RS33570"
                     /old_locus_tag="C8D88_111249"
     CDS             18676..19503
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077340.1"
                     /locus_tag="C8D88_RS33570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111249"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_109639985.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.3e-22,
                     bitscore: 72.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARTTVVIASRNRSASLLRTLTHLSELAVPVILVDNASTDDSVVL
                     VRQRFPHVEVLESPVNLGAVGRNLGVRAARTPFVAFADDDSWWAPDAFERAEPIFDDHP
                     DLAVIAARTLVGPAEKPDPITPLLRHSPLGQGVAGPAVLGFMACSAIVRRQAFLEVGGF
                     SPVLFFRGEETLLSWDLAAAGWALCYVEDVVAHHHPAVEREPGGDLLERRNAVLVTWMR
                     RPVHRAVAASLKDPRAFRAAVPRLRQALRQRRALPKHLERQIRTASGPPRRDA"
     gene            complement(19466..20545)
                     /locus_tag="C8D88_RS33575"
                     /old_locus_tag="C8D88_111250"
     CDS             complement(19466..20545)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (22-351). E-value:
                     5.8e-44. Score: 142.6. Matches aSDomain:
                     nrpspksdomains_C8D88_RS33575_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018682862.1"
                     /locus_tag="C8D88_RS33575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111250"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_211337589.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.4e-43, bitscore:
                     142.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASILFTRGAPSLDIIDQEGLREAAQKAFTDDPGGTFAYGTSVGY
                     VPLRQWLADQHGVEPEQVLVTNGSMQADAFLFELLVQPGDDVVVEAPTYDRTLLNLRQR
                     GAKIHAIELETDGINVDALEQLLESGVRPSLAHIIPNFHNPAGYTLSEAKRARLLDLAA
                     KYDFVLFEDDPYIKVRFEGEPLPTMLSQDENEKVVYASSFSKTMAPGIRCGYLVGPKTV
                     IKKIQDIATTTYISPNMVAQSIVNSYCRSGRIEESIVNVRTALRARRDALVNALKRELP
                     EAVFTAPQGGYFMWVELPGVSIEKLFGVAKEHGVEFVKGSDFLLEGGDNAMRLAFSGVT
                     PEQIDEGITRLAAAVRSLS"
     aSDomain        complement(19493..20479)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS33575_Aminotran_1_2.1"
                     /evalue="5.80E-44"
                     /label="C8D88_RS33575_Aminotran_1_2.1"
                     /locus_tag="C8D88_RS33575"
                     /protein_end="351"
                     /protein_start="22"
                     /score="142.6"
                     /tool="antismash"
                     /translation="EAAQKAFTDDPGGTFAYGTSVGYVPLRQWLADQHGVEPEQVLVTN
                     GSMQADAFLFELLVQPGDDVVVEAPTYDRTLLNLRQRGAKIHAIELETDGINVDALEQL
                     LESGVRPSLAHIIPNFHNPAGYTLSEAKRARLLDLAAKYDFVLFEDDPYIKVRFEGEPL
                     PTMLSQDENEKVVYASSFSKTMAPGIRCGYLVGPKTVIKKIQDIATTTYISPNMVAQSI
                     VNSYCRSGRIEESIVNVRTALRARRDALVNALKRELPEAVFTAPQGGYFMWVELPGVSI
                     EKLFGVAKEHGVEFVKGSDFLLEGGDNAMRLAFSGVTPEQIDEGITRL"
     gene            complement(20576..21727)
                     /locus_tag="C8D88_RS33580"
                     /old_locus_tag="C8D88_111251"
     CDS             complement(20576..21727)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015804246.1"
                     /locus_tag="C8D88_RS33580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_111251"
                     /product="PI-PLC domain-containing protein"
                     /protein_id="WP_211337590.1"
                     /transl_table=11
                     /translation="MPATANAAPSGTYYITSVRTGLNVAQSGTGVALHRPKGNEDHQQW
                     RLSDGRFENTDSPGQCITRQLTMGSCSQGDTVHEPRQFGDQWEFFGLGGETRWYLTPVV
                     NRTEPMPQDPRLDQMTFLTAHNAYANGVDGGFAPPFINLAKNQTRGIVQQLNDGVRGFM
                     LDIHQTPDGAILCHNSCTLVSKPVALNVDVQRIVDFLRNNRSEIVTVFLEDYVSADVLR
                     GELRRVQGLNDVLYRAEGVRENGWPTRSQLVSANKRLIIFTDHGKDGREDSGVLYQKDW
                     TVENHWSMGSGLGTSDWSCYSRWDEKPLTATGTFQPLFVMNHFRDVPFGSTATADNSKL
                     ANRAQQFCQPAARKKPNYLSVDLYHLGNAAQAVQQLNSYVYRP"
     misc_feature    complement(21872..21888)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.96"
                     /tool="antismash"
     misc_feature    complement(21930..21939)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
ORIGIN
        1 ttcacccggc cgatcccgct gacggacgtg ctgcgtgcgg cggccgcgga gatcgagcag
       61 taccagcggg tgatggtgca cacggcgccg aacgccgaag tggtcggtta tgtggcgagc
      121 gacctcgtcc ggctgctggc cgaacttctt gacaacgcaa cggctttctc gccgccgcac
      181 acgcaggtga cgatcagcgc gtcgatcgag gccggtgaca tcgtgcagat cgacgtggtc
      241 gaccacggca tcggcatcga cccggaggca ctggcggtcg tgaaccaccg cctcgaggcc
      301 gcaggcgagg gcgcggacgt ccaggtcttc cgtgaaatgg gacttttcgt cgtcggcagg
      361 ctggccgcgc gccatcagat cgtggtacgg ctcgatgccc gacaaggcaa gggcactcgc
      421 gcgatcgtgt tggttccggc ggaactggcc ccacggcggg aggagtcctg ggagtctttc
      481 cggggggaag cgatcgagca gcgtccggtg cggccggcga cgcctgccca gatgccgggt
      541 ccggcgtcgg gtccggcttc gtggttcgag tcaccgggtg ccgctccacc gcctccaccc
      601 gcaccagcac gccagtcgcc tgagtcggct cggggcttcc tcgacgcctt ccagcgcggt
      661 gtgcagcgag gccttcccga ccggcaggag agtcgatgag cacgcaggtg gaccagttcg
      721 gctggctggt caccaacttc accgagcgca cacccggaat cgagcacgcg gtggtgatct
      781 cggccgatgg tctggtcctg atctcgtcgt cgaggctgcc ggcgcacgtg gcaccccagt
      841 tcgcggcgat cgtcgcaggc gtggtgtcgc tcgcggagtc ggcgtgccag tgcttcgccg
      901 gtgagtcggt cgtgcgcacc gtggtgcaga tggaccgggg cgtgatgctg ctgatgtcga
      961 tcagcgacgg ctccgtcctc gcggtgctgg cgtcgtcctc gtgcgacgtc tcgcaggtcg
     1021 cctacgagat gacggtggtc gtgcggcagg tgggccagct gctcacgccg gaactgcggg
     1081 ccgagctggc atgaaccgag agcctgacga gcaggtcaac ttcggcgatc tgatcagcgg
     1141 tttcagcttc gacagcgaac ggatccgcaa gcgcggcaag aagaaggcca cgcgcgcggc
     1201 cgaacccccg ccggagccgg acccgtacgc cacgctgccg ttcgacgtgc cgccgctgcc
     1261 gtccatcgag tcgtcggcgt ccatcgtgcg cgcctacgcc tggacgggtg gccgcaccac
     1321 gtccgaggtg cacctggaga tcgagaccct ggtctcggtg aacgagttct cggcgaccgc
     1381 cgtgcgcccg gagcaccagg acgtgctggc gttgtgccac tcgccgcgtt ccgtggccga
     1441 gatcgccgcg ttgcgcggtc tgccgctggg cgtcaccaag gtgctgctcg gcgacatggc
     1501 cgcgcacggc ctgatcgacg tccaccgcac ggcttcctcg tacggcggcg atcgtcccga
     1561 tggtgctctg ctggaacgag tgctggccgg actgcgtcgg ctctgactcc gcacgagctc
     1621 cccggaccgc tgctacggtc gagatcacat ctggggaggt tgacgtggag tttcaggacg
     1681 tggtccggcg caggcgcatg gtgcgcaagt tcaccggcga gccggtcagt gacgagagca
     1741 tccagcggat catgcgcaac gcggtgcgtg gtccgtccgc cgggttctcg caggggcagg
     1801 gctttctggt gctgcagggg gagtcgctga agcggctcag cgagatgttc gagtggtggg
     1861 gcggggaggg cgccaagtcg gctccggtcg tcgtcatccc gttctcggcc aaggacgtct
     1921 acctcgaccg gtacgcgcag gccgacaagg ggtggacgga ccgcgacgag aaccgctggc
     1981 ccgtgccgta ctgggacatc gacacgggca tggccgcgct gctgatcctg cagaccgcgg
     2041 tcgacgaggg cctcggcgcg gtgttcttcg gcaccgacaa ggagacgtgg cccgagctgc
     2101 gggcggcgtt cggcgtgccg gacagctacg tgccgatcgg catgatcgcg atcggccacc
     2161 ccgcggagga gggcatctcc gagggtgcgt cgccgcggac gcgcaagcgc accccgttcg
     2221 aggagatggt ccactggggt cagtggaagt gaggtcgttc ggcctgctcg ggccgttgga
     2281 cgtggtgctc gacgggcacc acgtccacgt cccgtccggc aaacggcgtg tcatcctcgc
     2341 cgcgctgctg ctgcgtccag gccaggtggt cggcgtcgac gagctggtcg agctgaccgg
     2401 cgggtcgcgc aacgccctgc agaccgcggt cggcaggctg cgcgaggacc tcggccggcc
     2461 ggagctcgtg cagacccggc ccggcggcta cctgctggac gtgcggccgg acgaggtcga
     2521 cgtccaccgg ttcggcctgc tggaaccgcg ggaagcgctg aagctctggc gtggccgccc
     2581 gttcgcggac atcggcagcg acgcgctgga acgcgaccac gtgcccgcgc tgaccgagca
     2641 gtacctcgcg acgctggaag cgcggatcga ccaggatctg aagcacggca ggcacgagca
     2701 gctcgtcccg gaactgcgca cgctcaccgg gcagcaccct gccagggaac gcctgtgggc
     2761 ccagctgatc gtcgcgctgc accgctgcga ccggcagacg gaagcgctgc gggcctacga
     2821 cgacatccgc accaggctca ccgaggagct cggcctcgac cccggcaggg acctgcagca
     2881 ggcccatcag caggtcctca cggccgacaa ccggcccagg gcccgcaacg acctgcccgg
     2941 tgacatcccc gacttcgcgg gccgcgccga cgacctcgac gagatcctcg ccgccgtccc
     3001 gtccggctgc gtcgcgatca ccgcgatcga cggcatggcg ggcatcggca agaccacgct
     3061 cgcggtccgc gccgcccacc ggctggcgcc gaagttcccc gacgcgcagc tgttcgtgga
     3121 cctgcactcc tacacggagg gcgctgaacc gcgaacgccg tcggacgcgc tgctggcgtt
     3181 gctcaccgcg ctcggcgtgc ccgcgcagga catcccggac gggctggacg cccgcgccgc
     3241 caggtggcga gcggaaatgg cccaccgcaa ggcactcgtg gtgctcgaca acgccggtag
     3301 cgccgcccag gtccgcccgc tgttgcccgg caccggcctg gtcctggtca ccagcaggcg
     3361 caggctcgtc gacctcgacg ccgcgtaccc ggtgtcgctc gacgtgctgt ccgaagagga
     3421 ctcgctcaac ctgctcgcgc gcatcgtggg gcagaaggcc gatctcgacg ccgcccgcga
     3481 gatcgtccgg ctctgcggct acctgccgct ggccgtgcgc atcgtcggtg cccgttggcg
     3541 caccaggccc gcgtggtcgg cgcaggacct ggtgcgccgc ctcacccagc agcgcctcat
     3601 cgaactgaag gcgggggagc gcagcgtcgc gggtgcgttc gccctgtcct accagcaact
     3661 cacggccgac cagcagcggc tgttccggcg gctgggcctg cacaccggtg aggactggga
     3721 cgtgcacctc gccgcggcgg tggccggcac gacgcgggcg gaggccgaac gcctgctgga
     3781 cgaactgctc gacgtgcacc tggtgcagca acaggagaac ggccgctacc ggttccacga
     3841 cctcctggcc gaccacgcga aggccagtgt cgagccggac gagaaggacg aggccgtcgt
     3901 ccgcatcctc gaccactacc tgcacggcgc ggcgacctcc gcgcagcgga tcgcgcccgg
     3961 ccggcccgag atccactcga cggtgacgta cgagcagatc gatcctcccg tgttcgccac
     4021 gccggtcgag gcgttggcgt ggcaggaggc ggaacggcgg aacctcaggg cggccgtcta
     4081 cctggccgcg tacgaggggc actaccggta cgcctggcag ctgccgcacc acttcgcgca
     4141 cttcctgctg ttgcgcggat ccggccggga acgggtcgag gtgcagagcg tcgcgctcgc
     4201 agccgcgcac cacctcggtg atctgcaggc gcgcgcggaa gcgttgcgcg gcttgggatc
     4261 ggcgtacctc gggcaggaga actacgagaa ggccgcggag cacctgcacg aggcgctgga
     4321 tctgatgcgg cagatcggcg acgtgcgcgg tgaggcgtcg acgctggggc tgctcggcat
     4381 ggtcgcgcgg gaacagcgcg agttcgacaa ggcgatggag cactaccagc gtggtcttgt
     4441 gctgatgcgg caggtgggtg ccccgacggg ggaagcggac gcgctggagc acatcggcat
     4501 cctccacgcc gagcgcgggg agtacgacga ggcgctcacg cacctggagc atgcacttcc
     4561 gctgttgcag tcacgcggtg acgtgcgtgc ctacgctggg gttctgcacg acctggccta
     4621 cgcgcacttc ggtatgttca acgacaagga gagcaggtcc tgcgcggagc ggtcgctggc
     4681 cgcctaccgg gagtcgggtg accggcgtgg agagtcgatc gccgtggccg agttcgccta
     4741 ctggcggtac gagacgggtg acttcgccgc cgtccgggag atggtgcgcg aggtgcgcag
     4801 actgtgccgt gcgtacatga acctgccgga cgaccacgcg gtgctggcgg cgatggagga
     4861 gattcgcgac cacatcggtc aggtcgcgat gctcgtggcc ctgtcgctcg ctgcccaggt
     4921 ggacgggcgg ctgaccgagg cgatcggcca cacccagcgg tgcctggccg tcgtcagctc
     4981 gaccagccgc tggtggagca ggtacaaggt gctcggccag ctctccacgc tgcacctggc
     5041 gctcggcgac cgggagaccg ccgtccgcta cggcgaggag gcggtcgcgg ccgccgagga
     5101 cctgcgtcag cccagggcga gggccgtggc gaaacggatc ctcgctacag ccacagcgcc
     5161 agcagcacca gcgtcgtagc cacacccgcg accagtgcga aggcggtgta ctgggcgact
     5221 ctgtccgtgg tcctgcgcat tcccctggct cccctcggtg gtgatgccac cgagcgtggg
     5281 ggagcgcgtc cccacctcgt ccccaccgcg atcacaccgg cgaaattccg gtgagtcgcc
     5341 gctggactgc tccgaacggc ggtcgtacgc acgtcagtgc cgcctgagag ctccggatcc
     5401 cgtctcacca ccgtctcatt accgttgcgg cggaaggcga acttggctct acggtgacgc
     5461 ccgtggactt cgggattctg gggccgatcc aggcacgcga ctccggtgtg cggctcgagc
     5521 tcggcggtgt gcgcggtcag aaggtgctcg ccgcgttgct gctcgcgccg aaccgggtgg
     5581 tgccgctgac gcagctggtc gacgtggtgt gggacggtga gccgccgtcg accggcaagc
     5641 accagatcca gaagtcggtc ggcgacctga ggtccgcact cggcgtgccg ggcctgatcg
     5701 tcacggacgg tcccggctac cggatcgcgc tgggttccgc gacgctcgac gtcctcacgt
     5761 tcgaacggca cgtggcgacc gcgcagaccg tggaacccgc cgaggcggtc cggttgctgc
     5821 gcaccgctct ctcgttgtgg cgcggcccgg cgttggcggg cctggacggc caggtgctgc
     5881 gggtggaggc cgagcggctc gacgaacggc ggatcgccgt cgcgcagcag tgcttcgggc
     5941 tgcaactgga actcggccag cacgagcagg tgatcaccga gctgtccgcg ctggtggccg
     6001 cgaacccgtt ccgcgagcag ctggtcgagc agctgatgct cgcgctgtac cggtcgaacc
     6061 ggcaggcgga cgcgctggag ctgtacgacc gcacccgccg gttgctggcc gacgagctgg
     6121 gggtcgatcc cggccgcagc ctgcgcgccg cgcaccaggc gatcctgaac caggacagcg
     6181 agtccacgca cgtctctccg aaagcaccgg cgcagttgcc ggcggacctg gcgcggttca
     6241 ccggccggga gtcctatttg gacgcactcg acgccggact gtccgcgtcc accgtcgtga
     6301 tcacgtccat cgccggtacc gcgggcgtcg gcaagacggc tctggcagtg cactgggcac
     6361 accgcgtgcg ggacaagttc ccggacggcc agctctacct gaacctgcgc ggctacgacg
     6421 acgcccccgc cacgacaccg gccgaggcac tgacccagct catgcgcggg ctcggcgtgg
     6481 agccggacca gatcccgcgc gaggtcgacg agcaggcgag cacgtaccgc tcgatcctgt
     6541 cgacccggcg cgtgctgatc ctgctggaca acgcggcgag cgaggaccag gtccggccgc
     6601 tcctgcccgg cacgcccggt tgcgcggtga tcgtcaccag ccgcaacgac ctgcgcgggc
     6661 tgaccgcgct ggacgacgcc cgccgggtcg agctggacct gctgacggcg gacgaggcgc
     6721 acgcgctgat cacccgcgtg ctgggtgccg cgagggcgga caccgaaccg gaggcggtcg
     6781 ccgacctcgc cgcgttgtgc gggtacctgc cgctcgcgat ccggatcgcg gcggcgaacc
     6841 tcgcgtgccg gccgcacgac cggatcgctg acgccgtcgc ggatctcgcg cagggcaaca
     6901 ggctcgcgca gctctcgatc agcggtgacc gccgggccgc ggtgacggca gcgttcgagc
     6961 tgtcgctgaa gtcgttgccg gacgaggcct ccctgctgtt ccagcggctg ggactgttgc
     7021 cgcgcacgga cttcaccgcg cacacggcgt ccgtgctgat gggcgtggac gacgtgcgtc
     7081 cgttgatctc gttgctggag agcgcgagcc tgatcgagcc gcacacccgc ggccggttcc
     7141 gggtgcacga cctgctgcac ctctacgcgc gggaactggt cacctccgac gaggacgccg
     7201 ggcaggccgg cctgcggttg ctcgaccact acctgcacac gacggacgcg gcgctggacg
     7261 tgctggcgcc ggagatgtac cggctgtgcc gcgacggcac ctctgcgctc tcgttcggca
     7321 gcaaggaagc ggcactgtcc tggttggacg ccgagggcga ggcggtggcc atctgcgcgc
     7381 tgcgtgccga gccaccgcgc taccgctggg agctggcgga ctcgttgcgt cgcatgtggt
     7441 acctgcgtca gcagttcgac cggtggcacg agacggcgtc ggcagggctg ctggccgccg
     7501 agcaggagaa cgacctgcgc ggccaggcgt cgatgcacct gtcgctgggc acgatgcact
     7561 gcgagctgga cggcaggcag gggatcggcc acctggagac ggctttcgcg ctgtacgagg
     7621 aagcggacga ccgggccggg cagttccact gcctcaacaa cctctcggtc gtccatctca
     7681 cgctcggccg cacgcaggag gcgatcgggc tgctgcgcga cgccctgccg ctggtcgacg
     7741 acaacctccg gctgtcagcc gtcgtgcacc tcaacctcgg ggtggcgacc gcgcagaccg
     7801 gcaggctcac cgagtcgctc gcgcactacg agcaggcgcg ggaactgttg cggcaggccg
     7861 gtggcagcgt ctcggacacg ctggtggagt tcgctctggc cgagctgcac gtggtgctgg
     7921 gcgatccggt gcgggcgcgt gagcacgcgg tccggggcgc gcggatggcc gaggagtccg
     7981 gctcgcacgc gtggtggtac gtgctgcagt cggtcgaggc gaagatcgac cgcgacaccg
     8041 ggcgcactca gcgtgctttg acgcgtgcgc tcgctctggt cgacgaggcc gaggaaggcg
     8101 cggcggagct ctacgtgctg ctcggcctgg tgatcgcggg cagcgcctac caccggctgg
     8161 ggcggctgcg ggaggcgatc gaggcgctgc ggcgcgggct gcggctggcc ggctcgctgg
     8221 ggcgggtgga caacgagacc gagtacctga tcgacctggc ccgtgcgctg caggcggcag
     8281 gcgacgagcg gtcggccggt gagctcgccg agcgggcgct ggaccaggcg acgacgttcg
     8341 gcttcgcgat gcaacgcggc cgggcgctcg cgacgctggc gttgctgagc ctcaaggccg
     8401 gcgatgcgga acgggcgcgc ggcttcgccg cggaagcggt ggaggtgcag cgggagaccg
     8461 ggttcgtgct gggccaggcg gagtcgttgc tcgtgctggc gcgggtggcg gatcaccccg
     8521 ccgcgctgca ggaaacccga gcgatcgtcg cacgtctgac cggaccgcac ggcggtgatc
     8581 cggccggtgt tctgtgtgag actgacgtcg gctgagggtt tccggcagga gggggcggtg
     8641 tgcaggccga tctgttcccg cgcccgcacc agctgcccgc agccgtctcc gacttcgtcg
     8701 gacgcgaaga gctcgtccag tccatggtgg acttggtcac ccgttcccgc aggtgacctc
     8761 gtcgcggccc ggcggtggta ccagcgcggg ccggcggtgt acgagcggct cgcggacccc
     8821 gtcgggcggg cgtcggtgct gcggaacctg gcccggatgt cctgaccgcc gcccgttcgg
     8881 aactgtccgc gcgttcgacc ggaattcggt ttcgaagccg gtgccaggtg atttgatctt
     8941 ccggatgtga ggccgttgtg aggtattgct ccaacagagt gcttggctgg ctcgtaagat
     9001 tccgttaggg tcgcattcgc gagcaattgg caggggtgat ggcgttaccg aaaatcgccc
     9061 gaaaattgat caaaatttag ccacttgttc gattgcaacc aaaacgctgc tccgtccggg
     9121 tgtcgcattc cactacagga ccagtgaggc ctcacgctcc ggggtagcgg tcacggagac
     9181 gtgtgcgtgc agtggtgcga ggtcggccaa aaggggcttg cgagtcgtga gaatcggacc
     9241 agtcttgtct aatggcatcg ccgggacccg tccggcggac agtggcctcg accagggggt
     9301 ggaacgcacc atgggtggtg tcccgacgtt tccccacggc agaccgctga cgtgggcgga
     9361 cctggaggcg atgcctgatg acgggcaccg tttcgaactc gttgacgggg tgttggtgat
     9421 gagcccctcg ccccgtcctg tgcaccagcg ggtcgtcgcc cgcctgctgg tgacgctgac
     9481 ggctgtctgc ccgccggagc tggaggtcct ccccgctccg gtcgacgtgg tgctcgccga
     9541 cgacacggtc ttcatcccgg acctggtcgt gggacgtcgt gaacagttca cgaagcaggc
     9601 gctcatgggg ccgcccgtgc tggcggtcga ggtcctttcg ccccggacgc gacacgtgga
     9661 cctggaactg aagcgggcga agttccagga agtcggctgc gagaactact ggttgatcga
     9721 ctacgacggc ccgtggctgc gctgcctgca cctcgagaac ggggtgtacg tggaacaggc
     9781 gcggtcggaa ggcgaagaga tcatcgaact gcagtacccg ttcgcggtga agctcagcgc
     9841 ccagtcactg gtgcggtgag tggctatcgg tcaagaaggg ctgggctgaa cgggcgacac
     9901 cgcgatacaa acgtgtggat caaggtttca ccatctggcg tgcccgtgtg tgggctggtt
     9961 gcgtgcatcg cgttacgtcc aacgcgcgga ggtccagcac atgcagccgt tccagctgcc
    10021 ggagttctac acgccccacc ccgcccggct gaacccgaac ctcgagcgcg cccgcgtcca
    10081 cacgcgggca tgggcgcacg agatggacat gatcgacgtg ccgcagcacg gaacggtcgt
    10141 ctggacggac gacgacctcg agtcgcacga ctacgcgttg ctctgcgcct acacgcaccc
    10201 cgactgcgac ggtgagacgc tcgacctcat caccgactgg tacgtgtggg tgttctactt
    10261 cgacgaccac ttcgtcgagc tctacaagcg caacccggac atcaagggcg cgcaggccta
    10321 cctcgaccgg ctgccgctgt tcatgccggt caacggtgtc atcaccgcga cgccggccaa
    10381 cccggtggag aagggcctgg cggacctctg gcgccgcacg gtccccagcc actcgctcga
    10441 ctggcgcgag cggttcgcct ccaacaccaa gcacctgctc gacgagtcga tgtgggagct
    10501 gcacaacatc agcgctcacc ggctctccaa cccgatcgag tacatcgaga tgcgccgcaa
    10561 ggtcggtggc gcgccgtgga gcgcgaacct cgtcgagcac gcggttggcc tcgaagtgcc
    10621 ggcccagatc gccctgagcc gcccgatcgg tgtcctcagg gacacgttca gcgacgccgt
    10681 gcacctgcgc aacgacctgt tctcctacga gcgcgaggtc ctcgacgagg gcgagctgtc
    10741 caacagcgtg ctggtgttcg agaagttcct cgacctcccc acccaggacg ccgcggaggc
    10801 cgtcaacgac ctcctcacgt cccgcctgca ccagttcgag cacacggccc tcaccgaggt
    10861 cccgctgctg ctcgacgagc acgcgatcga ccccatcggg cgcgcggccg tgctgggcta
    10921 cgtgaagggc ctgcaggact ggcaggcggg tggccacgag tggcacctgc ggtcgtcccg
    10981 gtacatgaac aagggcctca ggacccagcc cggcacgtcc gcggccgacg tcctcggctc
    11041 gtacgcgagg acgatgccgc agcggctcaa gcagttcacg gccacgccca agatcgtcga
    11101 gccgtacccg cggccgacct acgacatccc gttcgcgctc gggatggccc cgcacctgga
    11161 ccagtgccgg gaggaggtca tcgcgtggag cgaggaggtc ggcttccacg gcgagggcat
    11221 ctgggacgag gccaagaacc gccgcttcga cctggcactg gcatcggtgt gcatggaccc
    11281 cgacggcacg ccgtccgagc tgttcctctc ggccgcctgg ctgacctggg gaacctacgg
    11341 cgacgacttc tacccgtggg tgttcgggcg gttgaaggac ctcgccgggc tcaagagcca
    11401 gaccgcgcgg ctgaagctgt gcatgccgct cgacctggtg ccgacgatcg tgccggtcaa
    11461 cgccgtcgag cggtctctcg ccgacctgtg gcagaagacc gccgcgccga tgtcgccgga
    11521 gttccggtcc acgttccgca aagccgtcga cgcgatgctg gacgcctggg cgtgggaagt
    11581 gatcaacatc cagcagaacc gcattccgga cccggtcgac tacctggaga tgcgccggtc
    11641 gacgttcggt tccgagctga cgacctcgct gtcgcgcttt tcgcattcga cgacggtgcc
    11701 gccggagatc tggggaacgc gggtcgttca gaccatggag cggtcggcca tggattacac
    11761 cttcatggtc aacgacacca tctcgtacct caaggaaatt cagtacgagg gtgaagtgca
    11821 caacatggtg cgggtcgtcg agaacttcct cggagtctcc cagccgcggg cgttcgagat
    11881 caccttcaag ctgatggacg cccggctcgg acagttcgtc caggccgtcg acgtcgacct
    11941 gccgaagctc ttcgaggacc tgtcactgga ctccgcgacg cgggcgtcgc tcacccggta
    12001 cgccgacgag ctgaaggact ggatcgtcgg cgtcacccac tggcacgtgg aaacctcgcg
    12061 ctaccacgag gaggagatcc gcaccccggt gaacgcccac ctgctggcgg gagcgttcaa
    12121 ccggggcccg tccgggctcg gcacgtcggc cgccaggctc gtcgctgtca agcgctgaca
    12181 gctcgtggtc agccggcggt cagtaccggt cggcaccttg tgggcaacac cgacccacag
    12241 ggggcaacac catgaagaac gtcctgatct ccggcgccag catcggcggc ccggcgctcg
    12301 cgtactggct gcggcaccac ggttttgccg tcacggtcgt cgagcgggcc cgcggtctgc
    12361 ggcccggcgg ccaggccatc gacgtccgcg gcccggcgct ggaggtgatc gagcgcatgg
    12421 gcctgggcga ccggctgcgg tcgctcagca ccaacatgcg cggcatgacc atgctcgacg
    12481 cggaaggcaa cgagctgttc agctccacca cgcacacgct cagcggcggc gagctcgcga
    12541 gccccgacgt cgagctcctg cgcgacgacc tcgcaacgat gctgttcgat gccgcggaag
    12601 gcgtggagta cctgttcgac gacacgatca ccgcgatcga cggcaccggc gtcacgttcg
    12661 agaaggccgc gccgcgcgac ttcgacgtga tcgtcggagc ggacggcctg cactccaacg
    12721 tccgccgcct ggtcttcggg ccggagtcgg agttcgtcag ccacctcggc atgaacctgg
    12781 cagtgttcac cgcgccgaac ttcctgaacc tcgaccactg gcagatcttc cagcaggacg
    12841 gcgaggtcgg tggcggcgtc atgagcgccc gcgccaacgc ggaatgccgt gtctacatgg
    12901 gattcaacgg cgaggcagac gtcgactacc gcgacatcga ggcgcaacgg cggctgatcg
    12961 ccgagaagtt cgccgacgcg ggctgggagt ggcagaacgc gctgaagcac atgtgggagg
    13021 cgccggactt ccacttcgac tcgatgagcc agatccgcat ggagacctgg tcgcgcggca
    13081 acgtcgtgct gctcggtgac gccggctact gcggctcgcc gttgtccggt cagggcacca
    13141 gcatggcgct ggtgggtgcc tacgtgctcg ccggtgagct ccgggacaac cccgccacgg
    13201 cgttccagcg ctacgaggag atcctgcggc cgtacgtgac ggccaaccag gacatggcgc
    13261 tgaagaaccg ggagaacggc ggggcgccct ccgaggagtt cgccgacgtc gtgaacagcc
    13321 tccagctccc cgcgtactga actccttcaa aattggctca gaccattgac ggcaaatggg
    13381 atgtttgacc aggctggaca ccgggtcgcc gcccccgcct cgtgaggagg agccgtgaga
    13441 actcgcgttc tcgccgcggt catcgctgtc accgccgcgc tgtccgttag cgcgcagtcg
    13501 caagccgcgg aaccactgca gagcctggta ccagttccag tgtcggtgca ggccagagcc
    13561 ggtgtcacgc acacgctgac ggccgccacg aagatctaca ccgcccctgc cgcgagggac
    13621 gtcggcaact tcctggcggg cgtcctgcgg ccgtcgaccg gctacgcgtt gccggtgtcg
    13681 gacacgaccg gcactccggc ggacggcatc tcgttgctgc tctcgggcgc gccgggcacg
    13741 gtcggccagc agggctacca gctcgatgtc gcggccggag ccgtcgtgct gcgcgccaac
    13801 acgccggagg gcctgttcgc gggcgtgcag acgcttcggc agatgctgcc cgcggctgtt
    13861 gagagtgcga ccgtgaagcc cggtccgtgg accgtgccgg gcgcgctgat cgtcgaccac
    13921 cctcggttcg cgtatcgcgg cgcgatgctc gacgtggccc gccacttcca cccggtggcg
    13981 tcggtcaagc gctacctcga ccagctggcg ctctacaaga tcaactactt ccacctgcac
    14041 ctgagtgacg accagggctg gcggatcatg atcgacagct ggccgcgcct cgccacgtac
    14101 ggcggcagca cgcaggtcgg cggcggtgcg ggcggctact tcaccaaggc gcagtacagc
    14161 gagatcgtgc agtacgcggc cgcgcgcagg atcacggtga tccccgagat cgacatgccg
    14221 ggccacacga acgccgcgct ggcctcgtac gcggagctga actgcaacgg ccaggccccg
    14281 ccgctgcgca cggacatcga ggtcggctac tcctcgctgt gcgtcaacaa ggacatcacc
    14341 taccagttca tcgacgacgt ggtgcgtgag atcgcggcgc tcacgcctgg cccgtacttc
    14401 cacatcggcg gcgacgaggc ccacgcgacc tccgacgccg actaccaggc gttcatgaac
    14461 cgcgcgctgc cgatcgtgaa gaagtacggc aagaccgtgc tcggctggca cgagttcgtg
    14521 aagaccacga ccgacaccac cgccatcccg cagtactggg gcaccacgac gtccaacgcg
    14581 acggtgcagg cagcggcggc acgcgggaac aaggtcgtca tgtcacccgc gaacaaggcg
    14641 tacctggaca tgaagtacaa ctccagcacg cctctcggtc tgtcgtgggc cgggttcatc
    14701 gaggtccagg acgcctacaa ctggaacccc ggcacgcacc tgagcggcgt tcccgagtcg
    14761 gccgtccgcg gcgtcgaagc tccactgtgg accgagacga tcgtgacgtc gcgcgacatc
    14821 gagttcatgg cgttcccgag gctcccggtg ctcgcggagc tgggctggtc gccgtggtcg
    14881 acgcacaact gggaccagtt caaggtgcgg ctgggcaacc aggcgccgcg ctggaccacg
    14941 atgggcatca acttctaccg gtccgcgcag gtcccgtggg acaccggcgg cccggcgccc
    15001 ggtccgtgcc cgcagcccgc gtgggagcgg tcgaaggtct acaccggcgg caacgtggtc
    15061 tcgcacaacg gccacaagtg gaccgcgcag tggtggacgc agggcgagga gcccggcacc
    15121 accggtcagt ggggcgtctg gcgcgacggc ggcgtttgct gagttcttct gggtactccg
    15181 tcgaccatga cggatccaga agaagccgaa gagttcgcgg aagaggtcgg tgtcgacccc
    15241 acgccccagg aggtcgacga ataccgcgac atgacggaac caggcgagtg gcgcgccgac
    15301 gagaagatgg ggccggacgg cgcgcccgca ccgcaggacg gagacgaccc gaccggcggc
    15361 tccggtgcat gatccggtgc gggcgaatac tgttcgctcg caccgggtaa ccggctgttg
    15421 tggatgcccg agttgccgtt tttgccccgt cccctcagct gaccgtcacc gtcgaggatc
    15481 tcgacggcga gcccgacgtg cacctgcacg cgggtggcca gggtttctgg cagtccagga
    15541 tgatcgcctc gctcggcgtc gaggccgtgg tgtgcgcggc gttcggcggt gagaccggcc
    15601 gcgtgttgcg gacgttgctg gaaggcgagc acatcgacct gcgcgcgcgt gaagtcgccg
    15661 cgcgcaacgg ctcgtacgtg cacgatcgcc gtgacggtga gcgctccgag atggtcgaga
    15721 tgttgccgga cgcgttgtcc cggcacgagc tggacgacct gtacgagtcg atgctggtgg
    15781 agggcatccg tgcgggcaca gccgtgctga gcgggccgtc cgacgaccgc gtgctgcccc
    15841 acgagacgta cttccgcctc acctccgacc tgacgaagaa cgactgccgc gtcatcgtcg
    15901 acctggccgg cgaacggctg gccgaagcgg tgcggggtgg cccgcacgtc gtcaaggtga
    15961 gccacgagga gctgggtgag gaagagctgc ccgagctggt gcgggcgtgc cggaagatcg
    16021 cttcttccgg cgtgcacggc gtggtggtgt cgcgtgccga cgagccggcg ttggccctgc
    16081 tcgacgagca gctgtacctg gtgcggatgc ctcggctgga gcccgtcgac acgcgcggcg
    16141 ccggtgactc catgaccgcg gggatttcag cgggcctcgc gctgggtatg tcgctggacg
    16201 acgcggtgaa gctcggcgcg gcggcgggcg cggtgaacgt gacgcggcac ggcctcggca
    16261 gtggcggggg agaagcggtg cgcgagctga gcaaacgcgt ggaactggag ccgatcgagg
    16321 aatgagcgga tgcgcgcgct gatcaccaac gacgacggaa tcgactctcc cggtctgctg
    16381 accctggcct ctgccgctgt ctcgtgcggg ctcgacgtcg tcgtcgcggc tcccgcgacc
    16441 cagtccagcg gcacgagcgc ctcggtcgcg gccgccagcg acaccggcag ggtggtcagc
    16501 gaacgccgta cgctgcccgg cctcgacgcg gaggcctacg cggtcgccgc gcacccggcc
    16561 ctgatcacgc tgatcgcgtg ccgcggcggg ttcggcggca aacccgacct ggtgctgtcc
    16621 ggcgtgaacc tgggcgcgaa cgtcggccgc gcgatcctgc actccggcac cgtcggcgcc
    16681 gcgctgaccg gccaactcaa cgacgtctcg tcgctcgcgg tgtcgctcga cgtcggattg
    16741 gacgggcccg aaccgttgtg ggacaaggcg gacgaggtcg tacgcgccgt gctgccggtg
    16801 ctgctcgaga tgccggccgc cacggtgctg tcgttgaacg tgccgaacat cgttgacgtg
    16861 caaggaattc gctgggcgaa gctggcgcgg ttcggctccg tgcagagccg ggtggacgag
    16921 gtggacgaga acgagatcga gctcgtcacc gtgtactcgg aggagtcgct ggtgccgggc
    16981 acggactcgg ccctgctggc ttccggctac gcgacgctga cgccgctgaa ctcggtctcc
    17041 gaggacgtca gctcgccgcg tccttccccg gcctggccag tgtgatcacg agcccgatca
    17101 acgcggtgcg aacctccagg aaaccctcgg tcgtcacgtc ttcgagcgag aaggccagca
    17161 ttccgaacga cagcaacaag aggattccgt acatccgtgc gaggtcgtgc cgccacgcca
    17221 tcacgacgcc cagcgccccg accccgatct ggatcacgtg gtagtcgggg tccaggccga
    17281 acacgtcgaa ccagccgagc gcgagctgca gtaccccagc cgtcagcgtc aggatctgtg
    17341 gcctcgtgaa ctccagttcg ttgctcagca aggccatggt ccgtcctacc cttcgaatcg
    17401 ccgccagacc gcgtcgtact tcgcttgtcg ttcgcgatcc cgggcggcgt ttcgctcccg
    17461 gcgtcccgag gtcgccgatc ctcgcgggta cccgtacttg gtgaggcggt aatccacgct
    17521 ttccggcgcg taggacaacg cgaagtacag tcctacaacg aaaccgagcg cgccgcacgc
    17581 gatggccagc ggccacggcg acccgaggcc gaacaccagc gccagcgtga tggccgtcgt
    17641 cagcggcgtg acctgcacca gactccggac ggtgaagcgc accaaccact tcggaccggt
    17701 cacgtccgcg tagacgaact cgcggtactt ctggggaacc ctgccgcccg cgtagtacca
    17761 gagcttcagc gccgggttca tctcgtggcc ttcgcgatca ctttgtgcag cacctcgttc
    17821 agctgcgcga gctcctcgaa cgtcatgtcc agctgctcca cgaccttgaa ggggatcttc
    17881 agcgcctcgg tgcgcagttc ccggccctgc tctgtgagcg tcagggccag cgcgcgctcg
    17941 tcgctcttgt ccctttggcg ctcgatgtaa ccgatcgcct ccagccgctt gaggagcggg
    18001 ctgagcgtgc cggggtccag ctgcagcacg gtgctgaggt ccttgacggt gcgcggcgac
    18061 cgttcccaga gggccagcat caccaggtac tggggatgtg tgaggttgag cggctccagg
    18121 atcgggcggt acaccgcgat caccgtgcgc gaggccacgg cgagggcgaa gcagacctgg
    18181 cgctccagct cgagcgggtt ctcggggata cttggtgtac taatcatttg tgtacacagt
    18241 aacctacgcc ttgccagggt agaagaggtg taacgggtcg agcgtgtctt tgaccgcgtg
    18301 ctgtacggca cagacgtcgg gccgagctcg cggatcatgc tgtcgcgttt gagcaggccg
    18361 acgccgtgct cgccggtgac gatgccgccg aggtccacgt cctggtcgat gatctccgcg
    18421 aacgccgcct tctgaacatc ctctgtggac tgtggatgga aggccgcggc cggggcgccg
    18481 gcgggcgccc actcggcttc gtcgtggctc aggttctcca gggtgacggg gtcggtgagc
    18541 aggccgggca ggtccaaggt cgtcatgacg gatcgagcgc tccgtgggcg gctttgtgca
    18601 cgactcgttc caggtccgcg ccccgttctt ccggcgacag ggtgttggag gcctgctacg
    18661 gggtagatga caggcatggc ccgcacgacc gtcgtcatcg cctcgcggaa ccgctccgcc
    18721 agcctgctgc ggacgctcac gcacctcagc gagctggcgg ttccggtgat cctggtggac
    18781 aacgcgtcca ccgacgacag cgtcgtcctt gtgcggcagc ggtttccgca cgtcgaggtg
    18841 ctggagtcgc cggtgaacct cggcgcggtc gggcgcaacc tcggcgtgcg ggcggcgcgg
    18901 acaccgttcg tggccttcgc ggacgacgac tcgtggtggg cgcccgacgc gttcgaacga
    18961 gccgagccga tctttgacga ccacccggac ctggcggtga tcgccgcacg cacgctcgtc
    19021 ggacctgcgg aaaagcctga cccgatcacg ccgctgctgc gccacagccc gctcggccag
    19081 ggcgtcgcgg gacccgcggt gctcgggttc atggcctgct cggcgatcgt gcggcggcag
    19141 gcgttcctgg aggtgggcgg cttcagcccg gtgctgttct tccgcggcga ggagacgttg
    19201 ctgtcgtggg atctcgcggc ggcggggtgg gcgctctgct acgtcgagga cgtggtggcg
    19261 caccaccatc cggctgtgga acgggagcct ggcggcgatc tcctcgagcg gcgcaacgcc
    19321 gtgctggtga cgtggatgag acggccggtg caccgcgcgg tggcggcgtc gctgaaggac
    19381 ccgcgggcgt tccgggccgc ggtgccccgg ctgcgccagg cgctccggca gcggcgtgcg
    19441 ctgccgaagc acctggagcg gcagatcagg acagcgagcg gaccgccgcg gcgagacgcg
    19501 tgatgccctc gtcgatctgc tccggcgtga cgccggagaa ggcgaggcgc atggcgttgt
    19561 cgccgccctc cagcaggaag tccgagccct tcacgaactc gacgccgtgc tccttggcga
    19621 ccccgaacag cttctcgatc gagacacccg gcagctcgac ccacatgaag tagccgccct
    19681 gcggcgcggt gaagaccgcc tccggcagtt cgcgcttcag tgcgttgacg agagcgtcgc
    19741 ggcgggcccg cagcgcggtg cggacgttga cgatcgactc ctcgatgcgg ccggagcggc
    19801 agtacgagtt cacgatcgac tgcgccacca tgttcggtga gatgtacgtg gtggtggcga
    19861 tgtcctggat cttcttgatg accgtcttcg ggccgaccag gtagccgcag cggatgccgg
    19921 gcgccatggt cttcgagaag gacgaggcgt agacgacctt ctcgttctcg tcctgcgaca
    19981 gcatggtcgg caggggctcg ccctcgaagc ggaccttgat gtacgggtcg tcctcgaaca
    20041 gcacgaagtc gtacttggcc gcgaggtcga gcagacgcgc gcgcttcgcc tcggacagcg
    20101 tgtagccggc cgggttgtgg aagttcggga tgatgtgcgc gagcgagggc cgcacaccgc
    20161 tctcgagcag ctgctccagc gcgtcgacgt tgatgccgtc ggtctccagc tcgatggcgt
    20221 ggatcttggc gccgcgctga cgcaggttca gcagcgtgcg gtcgtaggtc ggagcctcga
    20281 ccaccacgtc gtcgcccggc tggacgagga gctcgaagag gaacgcgtcg gcctgcatcg
    20341 agccgttggt gacgagcacc tgctccggct cgacgccgtg ctggtccgcg agccactggc
    20401 gcagcggcac ataaccaacg ctcgtgccgt acgcgaacgt gcctccgggg tcgtcggtga
    20461 aggctttctg cgctgcttcg cgcaggccct cctggtcgat gatgtcgaga gagggtgctc
    20521 cgcgcgtgaa cagaatcgag gccatgcgcg gagcgtacaa ctcccacgat ttgggctacg
    20581 gcctatatac gtatgagttg agctgctgca cggcctgggc cgcgttgccc aggtgataaa
    20641 gatcgaccga caggtagttc ggcttcttcc tggcggcggg ctggcagaac tgctgggccc
    20701 ggttcgcgag cttgctgttg tccgcagtcg ccgtgctgcc gaacggaacg tcgcggaagt
    20761 ggttcatgac gaacaacggc tggaacgtgc ccgtcgcggt gagaggtttt tcatcccatc
    20821 ggctgtaaca ggaccagtcg gaggtgccca gtcccgatcc catcgaccag tggttctcga
    20881 ccgtccagtc cttctggtac agcacgccgg agtcctcacg accgtccttg ccgtggtcgg
    20941 tgaagatgat cagacgcttg ttcgcgctca cgagctgact ccgggtcggc cacccgttct
    21001 cccgcacgcc ttccgcgcgg tagaggacgt cgttcagccc ctgcacccgg cgcagttcgc
    21061 cgcgcagcac gtcggcggac acgtagtcct ccaggaacac cgtgacgatc tcgctccgat
    21121 tgttccggag gaaatcaacg attcgctgga cgtcgacgtt gagcgccacc ggcttgctca
    21181 cgagcgtgca gctgttgtga cacaggatcg cgccgtccgg agtctggtgg atgtccagca
    21241 tgaagccccg cacgccgtcg ttcagctgct gaacgatgcc acgcgtctgg ttcttggcga
    21301 ggttgatgaa cggcggcgcg aacccgccgt cgaccccgtt cgcataggcg ttgtgcgcgg
    21361 tcaggaatgt catctggtcc agtcgcggat cctgcggcat cggctcggtc cggttcacga
    21421 ccggcgtcag gtaccagcgc gtctcaccgc cgagaccgaa gaattcccat tgatcaccga
    21481 actgccgcgg ctcgtgaacc gtatccccct gtgagcacga acccatggtg agctgacggg
    21541 tgatgcactg gccaggcgag tcggtgttct cgaacctccc gtcactcagt cgccattgct
    21601 ggtggtcttc gttgcccttc gggcggtgca gggccactcc agtgccgctc tgggcgacgt
    21661 tgaggccggt cctgacactg gtgatgtagt acgtgcccga cggagccgcg ttcgcggtcg
    21721 ccggcaccag gggaagtagc agcagggctg cgacagcagg gaggtatcac atggtgacca
    21781 gagtcaccca catgagtgag acatgaaacg tcctcaagcg tttggacgtt taacactgtg
    21841 ggtattccac gcaccgccag cacctcttca caggtagtac aactccaagg cagccgtcgc
    21901 ccagccgaag ggttagggcc ggtactgagc gccgccttca caagccgcgc agggttcgac
    21961 tccctcggtt gccgcgaact tcgtcgccca cccgcggcga gaagtacagg cgtcgtggtc
    22021 gacggaccgc ggcgcctttc tcgtttggaa ggacggcggt ccctcgcggg ccgtggtcag
    22081 aacggtggat cggcacccga tgcgaagtcg gccgcttcct cgcccggtgg gtcgcctcgg
    22141 cgtttaccca gggcgcgcag gcggtcgccg acgtactc
//
