LOCUS       NZ_QGHB01000006        26022 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Lentzea atacamensis strain DSM 45480 Ga0215650_106, whole genome
            shotgun sequence.
ACCESSION   NZ_QGHB01000006
VERSION     NZ_QGHB01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea atacamensis
  ORGANISM  Lentzea atacamensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 445113)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 445113)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Expected Final Version            :: No
            Genome Coverage                   :: 90.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003148865.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:35:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,333
            CDSs (total)                      :: 9,254
            Genes (coding)                    :: 9,110
            CDSs (with protein)               :: 9,110
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 6 (5S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 32 of 144
            Pseudo Genes (incomplete)         :: 121 of 144
            Pseudo Genes (internal stop)      :: 2 of 144
            Pseudo Genes (multiple problems)  :: 11 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:50:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 419091
            Orig. end                         :: 445113
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QGHB01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26022
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="3"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..26022
                     /SMILES="NC(CCCN)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26022
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:>26022](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>26022
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            776..1759
                     /locus_tag="C8D88_RS25090"
                     /old_locus_tag="C8D88_106312"
     CDS             776..1759
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D88_RS25090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D88_106312"
                     /product="hypothetical protein"
                     /protein_id="WP_109638257.1"
                     /transl_table=11
                     /translation="MHITSLSCRALVTVVATTVVTALLAPVASAAADCTWQRESLPILD
                     GMSWSNIRITGVDGQGNVSGFYSPGGDDRVLARWTTSGVEIVPKPEGVAKFVTRTGNAS
                     GVVGAIADRSDGTSVAMTHTPGSGYRELPTPAGYRVWGVEDINNRGDVVGRVNPTGSHE
                     WGAVLWRADGSAPEVIMPAGARSVTPVALGEDGTVLIDSMDGNFLWRNGALTQLPEVHY
                     SLNPRGLTRDGVIFSSYEESWKWTEATGAVEKFAVNGYVEAVNDSGLAVGYLDDGNYTP
                     VLWQGTEFVTRLPLSAGTYGSAGDAVSDSGFVAGVDATLPARWACR"
     gene            complement(1763..2704)
                     /locus_tag="C8D88_RS25095"
                     /old_locus_tag="C8D88_106313"
     CDS             complement(1763..2704)
                     /NRPS_PKS="Domain: PKS_ER (21-310). E-value: 7.5e-21.
                     Score: 66.5. Matches aSDomain:
                     nrpspksdomains_C8D88_RS25095_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020638226.1"
                     /locus_tag="C8D88_RS25095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106313"
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_109638258.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 9.7e-20, bitscore:
                     65.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAAVVDQLGRPPLMTGRDEPAVLEDHVVLDVLAAPITPLDLLCA
                     TGTSYFGSPATPYVPGVQGIGTVGGRAVWFPTVAGMAAGDGSMAEKALARQQDLVFLPD
                     DVPPVVMAALGLSAVAAHMALTWRGELSPGECVIVLGCGAVGQTAIQLARAAGAGRVVA
                     AARSEAGRERAKRAGADAVIALDADDLAGQFLEAAPDADLVLDPLFGPPAAAAAQALRP
                     GGRWVNLGGSAGETCPITSSVLRSRSLRLSGYTNNELSPQQRSEAISTIAHLAARGALG
                     VDHEVVPLADVADAWRRQSEGATRGRIVLVPR"
     aSDomain        complement(1775..2641)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS25095_PKS_ER.1"
                     /evalue="7.50E-21"
                     /label="C8D88_RS25095_PKS_ER.1"
                     /locus_tag="C8D88_RS25095"
                     /protein_end="310"
                     /protein_start="21"
                     /score="66.5"
                     /tool="antismash"
                     /translation="AVLEDHVVLDVLAAPITPLDLLCATGTSYFGSPATPYVPGVQGIG
                     TVGGRAVWFPTVAGMAAGDGSMAEKALARQQDLVFLPDDVPPVVMAALGLSAVAAHMAL
                     TWRGELSPGECVIVLGCGAVGQTAIQLARAAGAGRVVAAARSEAGRERAKRAGADAVIA
                     LDADDLAGQFLEAAPDADLVLDPLFGPPAAAAAQALRPGGRWVNLGGSAGETCPITSSV
                     LRSRSLRLSGYTNNELSPQQRSEAISTIAHLAARGALGVDHEVVPLADVADAWRRQSEG
                     ATRGRIVL"
     CDS_motif       complement(2246..2293)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25095_0001"
                     /evalue="2.40E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="C8D88_RS25095"
                     /protein_end="153"
                     /protein_start="137"
                     /score="13.8"
                     /tool="antismash"
                     /translation="IVLGCGAVGQTAIQLA"
     gene            complement(2686..3555)
                     /locus_tag="C8D88_RS25100"
                     /old_locus_tag="C8D88_106314"
     CDS             complement(2686..3555)
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0018576 - catechol 1,2-dioxygenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009712 - catechol-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013677013.1"
                     /locus_tag="C8D88_RS25100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106314"
                     /product="dioxygenase"
                     /protein_id="WP_109638259.1"
                     /transl_table=11
                     /translation="MQLVTEDNITALAEQRWATAKDPRTAQLITALVRHLHDFAREVRL
                     TEDEWMAAVKWLTATGQISDDKREEFILASDVLGLSMLVVQMNHRFDPAATPATVLGPF
                     HVEGSPDLGFGGDMSDDVDGTPLYITGTVRSLDGAPVAAVLDVWQADAEGAYEAQLPDV
                     DEARLRAKYRTRPDGSYCVRTIAPKGYSIPMDGPVGALIGQTEISHFRPAHVHFLVTAD
                     GHEPLITHLFEEGAEYLDSDVVFGTKQELVVAFEPREPGPAPDGGTCDVPWLEARYDFV
                     LQPCAPQS"
     gene            complement(3559..4338)
                     /locus_tag="C8D88_RS25105"
                     /old_locus_tag="C8D88_106315"
     CDS             complement(3559..4338)
                     /EC_number="4.1.3.34"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226684.1"
                     /locus_tag="C8D88_RS25105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106315"
                     /product="citryl-CoA lyase"
                     /protein_id="WP_109638260.1"
                     /transl_table=11
                     /translation="MADHYETALGASTPDTITLLGQDLANDVMGTVGFGELAFWLATQR
                     RPSAGETRLFEAVLAALADHGFTPTAIVSRLTYLSAPDSVQGALAAGLLGGGSRFLGVT
                     EDCGRFLHDVVSSAQLPEDEAGWDALALETVRAQGKARIPGLGHHVHKNGDPRTPRLFQ
                     IAAEEGLTGPHLSLFAAIGRVHPQVLGKTLPLNGAGTCGAVLADLGLPLELLRGFALLA
                     RTAGLIGQLAEELRHPVANQIFLSVDSNTRSVAPLEE"
     gene            complement(4331..5467)
                     /locus_tag="C8D88_RS25110"
                     /old_locus_tag="C8D88_106316"
     CDS             complement(4331..5467)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189: L-carnitine dehydratase/bile acid-inducible"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018334036.1"
                     /locus_tag="C8D88_RS25110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106316"
                     /product="CaiB/BaiF CoA-transferase family protein"
                     /protein_id="WP_109638261.1"
                     /transl_table=11
                     /translation="MPGGPLEGLLVADFSRVLAGPYATMLLADMGAEVIKVEGPQGDET
                     RTWMPPVRDDVSTYYLGINRGKRSIALDLRDEADAELGRELARRADVLIENFKPGGLAK
                     YGLDHPSVSAANPRVIYASITGFGSGDGRHVPGYDLMVQAISGLMSLTGDPDGPPYRAG
                     ISVFDVMAGNHAVIGILAALRHRDATGQGQLVEVNLLSSALTGLVNHSSAFVAGGVVPF
                     RMGNAHPSVFPYEPLPTADNDLIVAAANDGQFRRLCEVLGLPEVPDDPRFARNADRTRN
                     REELRPILLDRLRTRGAVEWFDLLVAAGVPCGPINTIDGGFAMAERFGLDPVVVVGDVP
                     TTRHPIRFSETPAVYKLPPPELDEHGDELRAWLKEDRG"
     gene            complement(5467..6897)
                     /locus_tag="C8D88_RS25115"
                     /old_locus_tag="C8D88_106317"
     CDS             complement(5467..6897)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018334039.1"
                     /locus_tag="C8D88_RS25115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106317"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_109638262.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.1e-32, bitscore:
                     107.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGERRPVVLRNGTVLTMDGQKRILTDHDVLVVGDRIAAIGPRLE
                     APPGTEEVDATGGIVLPGMIDTHRHLWQTAMRGYGADWTLTQYFVWYYLEWGKVFRPED
                     VYAGNILGAAEALDAGVTTTVDWSHGLQTTDHADAAVDALQQVPGRFVLAYGNIQDSPA
                     NWTAKPEFRDFVNRRITNDDMLGFQLAFDVTGDPAFPEKPAFEVARELGVPVTTHAGVW
                     GATNDDGIRLMHDNGFMTPQSIYVHAATLSADSYHRIAATGGSISVSTESEQSAGQGYP
                     PTWAIRAHGIPVSLSMDTSVWWSGDLFSAMRSTLGADRAREHMAAHAKNETVTHSSLRA
                     EHVVEWATMGGAKALGRDDLGSIEIGKKADIVLLRNDNSPAMFPVLNPYGHVAFQAQRS
                     DVDTVIVDGRIVKRDHRLIGVDLKAIRAAVEQTVEHLRAQLGEEAWEKGMNPDIPTAKV
                     LDNPYTYTEYRGDTRTSV"
     gene            complement(6974..7777)
                     /locus_tag="C8D88_RS25120"
                     /old_locus_tag="C8D88_106318"
     CDS             complement(6974..7777)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013678501.1"
                     /locus_tag="C8D88_RS25120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106318"
                     /product="IclR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_109638263.1"
                     /transl_table=11
                     /translation="MPARPDTGPDFIEALARGLDVIRAFQPLRPVMPLSEIAAATGLAR
                     PTARRILLTLIELGYARQCENGFALTPRVLELGVAYVRSTGLWEVARPHMERLGARTNE
                     SVSIAQLDGSDIVYVARVAVPKIVTLSVQIGTKFPALPTSLGKVQLAALPQEELEAVLA
                     QPTRSGLTPRWQPGAAERDAELRDVRARGWALTDQQLAPGIRSVAAPLRDGNSTVIAGI
                     NVNCHASETSVEHMVEHHLPLLLQTAGDISADFARLATVPHIVVA"
     misc_feature    7827..7841
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(7850..8620)
                     /locus_tag="C8D88_RS25125"
                     /old_locus_tag="C8D88_106319"
     CDS             complement(7850..8620)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (6-197). E-value: 4.9e-41. Score:
                     132.6. Matches aSDomain:
                     nrpspksdomains_C8D88_RS25125_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009078026.1"
                     /locus_tag="C8D88_RS25125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106319"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_109638264.1"
                     /transl_table=11
                     /translation="MDDVRVETTGTTTVIWMNRPDRRNAVDGPMARRLRDAFLAFEADE
                     TQRVAVLAGAGGTFCAGADLTSVNDPARRNDLDPDGAGPMGPTRLQPSKPLIAAVSGHA
                     VAGGLELALLADLRVAESDAVFGVFCRRWGVPLIDGGTVRLPRIVGLGRALDLILTGRP
                     VHADEALAIGLANRVVEPGQAVPAAIELAEQIAGFPFECVLADRASTYAGLDLPLAEAL
                     RAEGVGGVPIVAREGASGAARFTAGEGRHGRFES"
     aSDomain        complement(8030..8602)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS25125_ECH.1"
                     /evalue="4.90E-41"
                     /label="C8D88_RS25125_ECH.1"
                     /locus_tag="C8D88_RS25125"
                     /protein_end="197"
                     /protein_start="6"
                     /score="132.6"
                     /tool="antismash"
                     /translation="ETTGTTTVIWMNRPDRRNAVDGPMARRLRDAFLAFEADETQRVAV
                     LAGAGGTFCAGADLTSVNDPARRNDLDPDGAGPMGPTRLQPSKPLIAAVSGHAVAGGLE
                     LALLADLRVAESDAVFGVFCRRWGVPLIDGGTVRLPRIVGLGRALDLILTGRPVHADEA
                     LAIGLANRVVEPGQAVPAAIELAEQIAG"
     gene            complement(8649..9788)
                     /locus_tag="C8D88_RS25130"
                     /old_locus_tag="C8D88_106320"
     CDS             complement(8649..9788)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024945.5"
                     /locus_tag="C8D88_RS25130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106320"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_109638265.1"
                     /transl_table=11
                     /translation="MSHAMRRATELALDETTVMALRAALKTTADEVVEAIIDEVPSYAN
                     ALTGRMGGTIRRAVRTALGHYLDLAGGLATGVDAGDAAYELGRGEVRDGRSMDALLSAY
                     RVGARVAWRGLAAGAVSAGLPAEEVAKFAELTFAYIDELSAASAAGHADELAARGLAHE
                     RHLEQLARDLLAGAGADVLLAAAQRAGWQPPTSLTAVLLPAAQARPAYRSLDPSTLVLD
                     DLPDALGVLLVPDADRAHLLRQLTGRNAVVGPARPWTRASASYARAVRARSLSPDIRDT
                     EDHLPELVLSADPDAYADLRARALAPLRTLSASTARRLEETLRAWLLHHGRREEVATAL
                     FVHPQTVRYRMSQLRELFPDLGSPQRVLELTLAVGLTGR"
     misc_feature    9784..9799
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.8"
                     /tool="antismash"
     gene            9875..10930
                     /locus_tag="C8D88_RS25135"
                     /old_locus_tag="C8D88_106321"
     CDS             9875..10930
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018330220.1"
                     /locus_tag="C8D88_RS25135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106321"
                     /product="ferredoxin reductase"
                     /protein_id="WP_109638266.1"
                     /transl_table=11
                     /translation="MTSAALRSRAWKLLELVTTPLLPSDYLDLVSPLRAGADLRGRIEA
                     VNKETADAATIVIRPGRGWRGHTAGQYIRIGVDVDGVRLWRAYSVTSPSNRTDGRITIT
                     VKAIPDGKVSNHLVRKVKPGTVIQLDQACGEFVLPKTKPAKVLYLTAGSGITPVMGMLR
                     DTELADAVMVHSAPRQEDVIFRNDLHDLVADEKLRLVELHTDTHGMLDVARLHELVPDW
                     AERETWACGPTGLLDAAEQHWAEHDLADRLHTERFRPSVVVAGDGGEVTFSTTGKTVDA
                     DGATPLLDVGEGAGVLMPSGCRMGICFGCVTPLKAGAVRDLRTGEITEAEPGVLIQTCV
                     SAAAGPCDIER"
     gene            10982..12100
                     /locus_tag="C8D88_RS25140"
                     /old_locus_tag="C8D88_106322"
     CDS             10982..12100
                     /EC_number="1.14.19.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010225294.1"
                     /locus_tag="C8D88_RS25140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106322"
                     /product="acyl-CoA desaturase"
                     /protein_id="WP_109638267.1"
                     /transl_table=11
                     /translation="MSAIDPTAHLTAEQIEELGRELDAIRDEVMSSRGEKDAAYIRKVI
                     SVQRKLELASRGVLLFSIFPPAWLVGTAGLSVAKILENMEIGHNVLHGQWDWMRDPKIH
                     STTWEWDHVSPAEQWKHSHNELHHTYTNVIGKDNDLGYGIMRVDEDQKWHPMHLGQPLW
                     NFINACFFEYGIAAYDLELGKNLHKRRRKNPEFRARAKAVGRKIRRQVLKDYVIHPLLS
                     GPSFLTTLAATFTANLVRNLWSHSVIMCGHFPEGVQVFERRSIKGETRGQWYLRQMMGS
                     ANISGSKLMHIMTGNLSHQIEHHLFPDLPSNRYAEVAVKVRALFEKYELEYVTGSMPKQ
                     VFSAWHKVFRLSLPNKKPKTKTPARDKELVAA"
     misc_feature    complement(12108..12123)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.83"
                     /tool="antismash"
     misc_feature    12109..12123
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.83"
                     /tool="antismash"
     gene            12153..12773
                     /locus_tag="C8D88_RS25145"
                     /old_locus_tag="C8D88_106323"
     CDS             12153..12773
                     /GO_function="GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020119.5"
                     /locus_tag="C8D88_RS25145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106323"
                     /product="CocE/NonD family hydrolase C-terminal
                     non-catalytic domain-containing protein"
                     /protein_id="WP_170155031.1"
                     /transl_table=11
                     /translation="MRSVRGARFPTPAAGPGPPNGGSHAKGQPRRGHPADGRDDHHAHL
                     SRGSCRDHRIASNRPSTPLTALLVDYGPSTQAVLTDRSPLQLSTETCTRTDLRERTGCA
                     RRPAVSVQAVTATMLTRGAIDAKNRESLESSTPLPANATADVTWRLHARDAVIPAGHRI
                     GVVIVTNHGGYINQDTGANGIALQVSLGASKVVLPIVGGAVIT"
     gene            complement(12798..14282)
                     /locus_tag="C8D88_RS25150"
                     /old_locus_tag="C8D88_106324"
     CDS             complement(12798..14282)
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032115.1"
                     /locus_tag="C8D88_RS25150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106324"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_109638269.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1e-09, bitscore:
                     32.4, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 5.4e-08, bitscore: 27.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADLDVLIVGAGISGLGAAYYLQREHPRKTYAILEARGAIGGTWD
                     LFRYPGIRSDSDLHTFGYEFKPWRDEDSIAAADKILAYLRETAEEHDIDRAVRFHTRVI
                     AAEWSSPDAHWTVEVEKDGERETLTCSWLFCAGGYFRYDEGFTPHFEGRERFRGQLIHP
                     QHWPEDLDYAGKRVLVIGSGATAVTIVPAMAPAAGHVTMLQRTPTYVLPVPARDPIGNA
                     LRKLLSPERSFAIMRRKNILQQQLTWRFSRRFPNAARRLIRRFNARLLPEGYPVDEHFN
                     PPYNPWDQRLCVVPDGDLFTAIRSGKASVVTDRITTFTETGVLLESGRTLEADIVITAT
                     GLNVQAFGGMTLTVDGEPVRLPDTLAYKGMMLSGVPNFAYAIGYTNSSWTLKVGLLCEH
                     FCRLLAHMDEHGYDTARPVVADPGAPTRPFLDFGAGYVRRVLDQLPRQGERAPWLTSMS
                     YFSDVKLLRRLPVEDDELRFSRSRADRPVERLNESR"
     misc_feature    14300..14315
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            14364..15569
                     /locus_tag="C8D88_RS25155"
                     /old_locus_tag="C8D88_106325"
     CDS             14364..15569
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332522.1"
                     /locus_tag="C8D88_RS25155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106325"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_109638315.1"
                     /transl_table=11
                     /translation="MSWERPSPRVRELIRRGAEIALDPPAEWLAELDTATLSGPNRQQV
                     AEDPVLAAALKRTNRSNLLGWASANIRAPGERVPADLGEAPLAFARDLIRRGLDESALD
                     AYRSGQGVALRLWMQIAFSLTSDHEELRELIDVSCRSISAFVDDTVAAVSAQMAREREE
                     LTRGTHAERLETVTLLLDGAPITVSRAEQRLGYRLSGDHTAAIVWSDDALGDLDRVADV
                     LATAAGDPRPLTVLASAATRWVWVHGTPDDAVLRAGVARFPAARVALGSSGSGADGFRR
                     SHLDALTVQRMVARLASPQQLATHEEVELVALLTTDAERADRFVRRTLGPLATADPEVT
                     EAVRAFIAASCNATTAAARLYTHRNTLLRRLARASKLLPRPLEHNLVHVGVALEVHRWR
                     AQ"
     gene            15620..16642
                     /locus_tag="C8D88_RS25160"
                     /old_locus_tag="C8D88_106326"
     CDS             15620..16642
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005166167.1"
                     /locus_tag="C8D88_RS25160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106326"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_109638270.1"
                     /transl_table=11
                     /translation="MKKIGFLSFGHWSDSPHSQTRSASDTLLQSIDLAVAAEELGADGA
                     YFRVHHFAQQLASPFPLLAAIGAKTERIEIGTGVIDMRYENPMYMAEDAGAADLIAGGR
                     LQLGISRGSPEQVIDGWRHFGYQPAEGETDADMARRHSEVFLKLLEGKGFARPNPRPMF
                     PNPPGLLRLEPHSPGLRDRIWWGAGSNGTAVQAAEQGMNLMSSTLKFDEGGAPFHVQQA
                     EQIRAFRKAWTEAGHPREPRVSVSRSIFAITTDLDDAYFGGEGESTDQVGFIDGPNRAI
                     FGRSYAAEPEVLVEQLAGDEAIAEADTLLLTVPNQLGADYCAHVIENILVHVAPALGWR
                     "
     gene            complement(16662..17228)
                     /locus_tag="C8D88_RS25165"
                     /old_locus_tag="C8D88_106327"
     CDS             complement(16662..17228)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013382.5"
                     /locus_tag="C8D88_RS25165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106327"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_109638271.1"
                     /transl_table=11
                     /translation="MASMSNVLRSVSVSGVYRLAARRIVLPWVLGQVRPAGSLLEIGAG
                     SGAMSAELLARHGDLTAVVTDFDPRMVESAQRVLAPFGARATARQADATALPFEDGRFD
                     AVLSCGMLHHVGDWRAALAEVVRVLRPGGRFVGYDIVRTRPVELLGLGTATMIRPGELR
                     EAFAELPVTAGVRGSSLTRFSAVKR"
     gene            complement(17302..18789)
                     /locus_tag="C8D88_RS25170"
                     /old_locus_tag="C8D88_106328"
     CDS             complement(17302..18789)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014425.5"
                     /locus_tag="C8D88_RS25170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106328"
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="WP_211337440.1"
                     /transl_table=11
                     /translation="MATRTGVAVPLARRPVAVVAALYAALMFAVAANYGLSADELYFRL
                     LGDVPRWGYFDQPPLAPLLAKAGALLLGDTIWGIRLPAVLCGVAVVVLAALTAAELGGG
                     RRAQVLAAAAVATSVTVLTIGHFLLTNSPDLVAWCAVALFALRALLRGDGRWWLAAGVT
                     CGVATYAKYVVLLLPLTLLVALVLVGPRRELRSRWLWAGAGLTLVIGAPNLVYQAVNGW
                     PQLVMARSLAEGQWSDAALFPFDVAVLIGPAVAPILLAGLVSLLRRQGWRPARTLAVAY
                     LVGTALVLVVAPSGIDYTEGYLVPLVAAGCVVADGWLAQHPVRLPVAVSVLSLFALGQV
                     VMTLPVVPERMYAQYPTTSLTTETIGWPRLVGQVTDAYAELPADERSRAVVLVQNFGEA
                     GALRWLHDDRPLPRVYSGHNELYSWGPPPETADVVITVAVDDERLTRDFRECSVVARID
                     NGYGLETREQGRSVAVCRGLRAPWTELWPKYRLVGPY"
     misc_feature    complement(19376..19390)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.19"
                     /tool="antismash"
     misc_feature    19377..19391
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.56"
                     /tool="antismash"
     misc_feature    complement(19938..19950)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            20001..>26022
                     /locus_tag="C8D88_RS25175"
                     /old_locus_tag="C8D88_106329"
     CDS             20001..>26022
                     /NRPS_PKS="Domain: Condensation_Starter (9-298). E-value:
                     1.1e-71. Score: 233.6. Matches aSDomain:
                     nrpspksdomains_C8D88_RS25175_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (464-859). E-value: 1.8e-89.
                     Score: 292.1. Matches aSDomain:
                     nrpspksdomains_C8D88_RS25175_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (966-1033). E-value: 5.8e-26. Score:
                     82.5. Matches aSDomain: nrpspksdomains_C8D88_RS25175_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1045-1318). E-value:
                     6.6e-107. Score: 350.0. Matches aSDomain:
                     nrpspksdomains_C8D88_RS25175_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1323-1472). E-value: 1.9e-36.
                     Score: 117.2. Matches aSDomain:
                     nrpspksdomains_C8D88_RS25175_TIGR01720.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1480-1771). E-value:
                     3.5e-93. Score: 303.9. Matches aSDomain:
                     nrpspksdomains_C8D88_RS25175_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="C8D88_RS25175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_106329"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_146231628.1"
                     /sec_met_domain="AMP-binding (E-value: 8.8e-96, bitscore:
                     315.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7e-15, bitscore:
                     49.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.5e-58, bitscore:
                     191.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGRREPGVRYSLTAAQLDMWLSAELLGDTPEFNPAQYVVLRGPV
                     DDELLRGSALVAARETDAYRLFFGEHADGAPWQALADGLPADVMPVVDLRGEDDPAAAA
                     AAWMHADGARPIDHRVAPLWRWALLRVAADESWWYHRSHHLICDIFSFNLLTQRVAEIY
                     SAAHRPRYFGSWADVVAEDQAYQRSADRVADERYWLDSVAEAVQSRQDEHRPERQRPSR
                     RRTVAVDAALRGAVLDRCADLGLRVPHFLVAAFAAYQRQLTDRDDVLFSLPTAARRSLL
                     ARSTPGLLANVAPVVLHLPDGTTVRQLTGATTARLAEITARSRYRGEDLARKLGVAGNG
                     AWFGPVLNVVDFNRPVRFGAAVQADVPRNLSVGPVRDLTVTTYGWSRGDHSWLDIDVED
                     GVAAGAELALHEERFLELLDRLARGPVDGATPSSTVDLRLTGQWGAGAAPGATASVPDL
                     IASHTVAWPDRTAVVCGQDQLSFGELGKRADALAVRLRQVGVTVESAVAVLVPRGLELA
                     VAFQGVLRSGGVYVPVNPGLPAERLAFLLADVGATVAVTTAALAGELAGFAGEVLVLDD
                     SSPAADAALVRINPDALAYVAYTSGSTGRPKGVAVTHAALSSYVDGWRQALAPLGGAGT
                     VLSMSGPGFDVSIGDMTRALAFGQTVVFLPHDEAVSVDSLHRTLADHEVEIAEIVPGML
                     LRDLAAHCRAAGPVESLRLVISGTDMWTYDALVSAVAAVAPNAVPGNVFGVTEAAIDSI
                     FHPVTARPEHEGEVVPIGGPLAGVDAFVVDGWLRPVPVGVEGELLVGGAGLARGYAGRP
                     DLTAERFLPDVFGGSGGRLYRTGDRARWRADGVLEFLGRVDEQVKIRGYRVEPGEVEVV
                     IGDHPDVRDVVVVARDGGPHGGKRLVAYVVAENQNLAGVQLRSWLRERVPDYLVPSVLV
                     TLDRLPLTPNGKVDRRGLPDPEPGTAEAYEAPRTSTEDALATVWSQVLGVERVGVHDNF
                     FELGGDSILSLQIVARARAAGLGVDVADVLSHQTVAELAAVVRDAPAVTTAEQGVVTGP
                     VPFTPIQRWFLAQDIPDRDHWNWSGVFELAPGTDADCLASALNAVVAHHDALRIRFTPE
                     GQYNAGIEHAGLRVVAVHDDEVPAEMSTAQKSLRLADGPLVAAVFFDRGSQPAWLGLVV
                     HHVVMDGVSWNVLLEDLDTAYRSEALGAKTSSFQQWAEHLLELEVGGEREHWVAATSDV
                     VALPVDHDGPNNERSARIHTTWLDAGTTAVLLGDAHKAYRTQGNDLLLAALVRTLGPWA
                     GTDELTIDLESHGREGLDLSRTVGWFTSIFPVRLSRHADLGTTVKTVKEQLRAVPRRGV
                     GYGVLRWLRGELADAPDRPVLFNYLGSAAGTGDLLRRELPATLRGAATAGRGTRSHVLN
                     LEVTRTAGGQLQVEWHYSADLHDAATVERLAETYQRELEELVEHCRSGVSGLTPSDFPL
                     ASLAQNEVDRLAARFPELVDVYRLAPVQSGMLFGVVGAPADGDGLYWGQGIYELTGTVD
                     ADRLAGAWRTVIARQPALRSGFVWEGVSEPVQVVLADVDVPLQLRDWSGLDGDTQQERL
                     RELLAQDRALGFDLAAPPLTRLYLVDRGCGQYWLVWGLYQGLCDGWSLPVVMDEVSAVY
                     QGEALAPVRSYREFIAWLDRRDPAEPERFWRTYLDGFEAPTPLPVDRLASSHYAQDRRR
                     TALSADVTAKIVDLARRERVTLSAVVQAAWAKVLSASSGEDEVVFGLTVSGRPPELAGV
                     ESTVGLFINTLPVRAVVPSDVPFTSWLRELRDNQVALQRFECSPLVDVQRWSAVPAGRA
                     LFDSIVVLRNYPGGRTRVADFELSPLLDSVEQGNYPLTFAVDVDATLRIEAEYSTAAFD
                     AVTVERILHQLTVVLAAVAEQPELAVRDVPLQRPEQAAALVAWGAGPVPAAERPVPDLI
                     DGWARTSAEVAVICGEERLTFAELGARADALAGRLRRRGVTTESPVAVLVPRGIELAVA
                     FQGVLRSGGVYVPVN"
     aSDomain        20028..20894
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS25175_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="1.10E-71"
                     /label="C8D88_RS25175_Condensation_Starter.1"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="298"
                     /protein_start="9"
                     /score="233.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLICDI"
                     /tool="antismash"
                     /translation="RYSLTAAQLDMWLSAELLGDTPEFNPAQYVVLRGPVDDELLRGSA
                     LVAARETDAYRLFFGEHADGAPWQALADGLPADVMPVVDLRGEDDPAAAAAAWMHADGA
                     RPIDHRVAPLWRWALLRVAADESWWYHRSHHLICDIFSFNLLTQRVAEIYSAAHRPRYF
                     GSWADVVAEDQAYQRSADRVADERYWLDSVAEAVQSRQDEHRPERQRPSRRRTVAVDAA
                     LRGAVLDRCADLGLRVPHFLVAAFAAYQRQLTDRDDVLFSLPTAARRSLLARSTPGLLA
                     NVAPVVLH"
     aSModule        20028..24416
                     /complete
                     /domains="nrpspksdomains_C8D88_RS25175_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_C8D88_RS25175_AMP-binding.1"
                     /domains="nrpspksdomains_C8D88_RS25175_PCP.1"
                     /domains="nrpspksdomains_C8D88_RS25175_Epimerization.1"
                     /domains="nrpspksdomains_C8D88_RS25175_TIGR01720.1"
                     /locus_tags="C8D88_RS25175"
                     /monomer_pairings="Orn -> D-Orn"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20097..20210
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0001"
                     /evalue="2.70E-07"
                     /label="C2_starter_024-063"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="70"
                     /protein_start="32"
                     /score="23.2"
                     /tool="antismash"
                     /translation="FNPAQYVVLRGPVDDELLRGSALVAARETDAYRLFFGE"
     CDS_motif       20427..20489
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0002"
                     /evalue="5.50E-08"
                     /label="C3_starter_134-155"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="163"
                     /protein_start="142"
                     /score="25.6"
                     /tool="antismash"
                     /translation="HHLICDIFSFNLLTQRVAEIY"
     CDS_motif       20520..20555
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0003"
                     /evalue="9.50E-04"
                     /label="C4_starter_171-183"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="185"
                     /protein_start="173"
                     /score="12.4"
                     /tool="antismash"
                     /translation="SWADVVAEDQAY"
     CDS_motif       20799..20885
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0004"
                     /evalue="2.30E-05"
                     /label="C5_starter_265-294"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="295"
                     /protein_start="266"
                     /score="16.9"
                     /tool="antismash"
                     /translation="DVLFSLPTAARRSLLARSTPGLLANVAPV"
     CDS_motif       20961..21047
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0005"
                     /evalue="4.40E-07"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="349"
                     /protein_start="320"
                     /score="22.5"
                     /tool="antismash"
                     /translation="ARSRYRGEDLARKLGVAGNGAWFGPVLNV"
     aSDomain        21393..22577
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS25175_AMP-binding.1"
                     /evalue="1.80E-89"
                     /label="C8D88_RS25175_AMP-binding.1"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="859"
                     /protein_start="464"
                     /score="292.1"
                     /specificity="substrate consensus: Orn"
                     /tool="antismash"
                     /translation="AWPDRTAVVCGQDQLSFGELGKRADALAVRLRQVGVTVESAVAVL
                     VPRGLELAVAFQGVLRSGGVYVPVNPGLPAERLAFLLADVGATVAVTTAALAGELAGFA
                     GEVLVLDDSSPAADAALVRINPDALAYVAYTSGSTGRPKGVAVTHAALSSYVDGWRQAL
                     APLGGAGTVLSMSGPGFDVSIGDMTRALAFGQTVVFLPHDEAVSVDSLHRTLADHEVEI
                     AEIVPGMLLRDLAAHCRAAGPVESLRLVISGTDMWTYDALVSAVAAVAPNAVPGNVFGV
                     TEAAIDSIFHPVTARPEHEGEVVPIGGPLAGVDAFVVDGWLRPVPVGVEGELLVGGAGL
                     ARGYAGRPDLTAERFLPDVFGGSGGRLYRTGDRARWRADGVLEFLGRVDEQVKIR"
     CDS_motif       21564..21599
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0006"
                     /evalue="1.90E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="533"
                     /protein_start="521"
                     /score="8.8"
                     /tool="antismash"
                     /translation="GVLRSGGVYVPV"
     CDS_motif       21780..21839
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0007"
                     /evalue="1.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="613"
                     /protein_start="593"
                     /score="30.4"
                     /tool="antismash"
                     /translation="AYVAYTSGSTGRPKGVAVTH"
     CDS_motif       22368..22457
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0008"
                     /evalue="1.70E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="819"
                     /protein_start="789"
                     /score="49.1"
                     /tool="antismash"
                     /translation="PVGVEGELLVGGAGLARGYAGRPDLTAERF"
     CDS_motif       22542..22607
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0009"
                     /evalue="1.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="869"
                     /protein_start="847"
                     /score="36.2"
                     /tool="antismash"
                     /translation="FLGRVDEQVKIRGYRVEPGEVE"
     misc_feature    22785..22787
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        22899..23099
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS25175_PCP.1"
                     /evalue="5.80E-26"
                     /label="C8D88_RS25175_PCP.1"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1033"
                     /protein_start="966"
                     /score="82.5"
                     /tool="antismash"
                     /translation="EDALATVWSQVLGVERVGVHDNFFELGGDSILSLQIVARARAAGL
                     GVDVADVLSHQTVAELAAVVRD"
     CDS_motif       22905..22937
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0010"
                     /evalue="5.80E+00"
                     /label="Cy4"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="979"
                     /protein_start="968"
                     /score="0.4"
                     /tool="antismash"
                     /translation="ALATVWSQVLG"
     aSDomain        23136..23954
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS25175_Epimerization.1"
                     /evalue="6.60E-107"
                     /label="C8D88_RS25175_Epimerization.1"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1318"
                     /protein_start="1045"
                     /score="350.0"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHVVMDG"
                     /tool="antismash"
                     /translation="TGPVPFTPIQRWFLAQDIPDRDHWNWSGVFELAPGTDADCLASAL
                     NAVVAHHDALRIRFTPEGQYNAGIEHAGLRVVAVHDDEVPAEMSTAQKSLRLADGPLVA
                     AVFFDRGSQPAWLGLVVHHVVMDGVSWNVLLEDLDTAYRSEALGAKTSSFQQWAEHLLE
                     LEVGGEREHWVAATSDVVALPVDHDGPNNERSARIHTTWLDAGTTAVLLGDAHKAYRTQ
                     GNDLLLAALVRTLGPWAGTDELTIDLESHGREGLDLSRTVGWFTSIFPVRL"
     CDS_motif       23154..23180
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0011"
                     /evalue="9.10E-03"
                     /label="NRPS-E1"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1060"
                     /protein_start="1051"
                     /score="9.3"
                     /tool="antismash"
                     /translation="TPIQRWFLA"
     CDS_motif       23244..23315
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0012"
                     /evalue="4.40E-06"
                     /label="C2_starter_024-063"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1105"
                     /protein_start="1081"
                     /score="19.3"
                     /tool="antismash"
                     /translation="DADCLASALNAVVAHHDALRIRFT"
     CDS_motif       23487..23549
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0013"
                     /evalue="3.00E-09"
                     /label="NRPS-E2"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1183"
                     /protein_start="1162"
                     /score="29.2"
                     /tool="antismash"
                     /translation="GLVVHHVVMDGVSWNVLLEDL"
     CDS_motif       23811..23849
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0014"
                     /evalue="2.80E+01"
                     /label="Cy4"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1283"
                     /protein_start="1270"
                     /score="-1.7"
                     /tool="antismash"
                     /translation="LLLAALVRTLGPW"
     CDS_motif       23904..23954
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0015"
                     /evalue="3.90E-09"
                     /label="NRPS-E5"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1318"
                     /protein_start="1301"
                     /score="28.4"
                     /tool="antismash"
                     /translation="DLSRTVGWFTSIFPVRL"
     aSDomain        23970..24416
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS25175_TIGR01720.1"
                     /evalue="1.90E-36"
                     /label="C8D88_RS25175_TIGR01720.1"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1472"
                     /protein_start="1323"
                     /score="117.2"
                     /tool="antismash"
                     /translation="LGTTVKTVKEQLRAVPRRGVGYGVLRWLRGELADAPDRPVLFNYL
                     GSAAGTGDLLRRELPATLRGAATAGRGTRSHVLNLEVTRTAGGQLQVEWHYSADLHDAA
                     TVERLAETYQRELEELVEHCRSGVSGLTPSDFPLASLAQNEVDRL"
     CDS_motif       23991..24053
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0016"
                     /evalue="1.80E-10"
                     /label="NRPS-E6"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1351"
                     /protein_start="1330"
                     /score="32.9"
                     /tool="antismash"
                     /translation="VKEQLRAVPRRGVGYGVLRWL"
     aSDomain        24441..25313
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS25175_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="3.50E-93"
                     /label="C8D88_RS25175_Condensation_DCL.1"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1771"
                     /protein_start="1480"
                     /score="303.9"
                     /specificity="C activity: inactive"
                     /specificity="Active site motif: YQGLCDG"
                     /tool="antismash"
                     /translation="DVYRLAPVQSGMLFGVVGAPADGDGLYWGQGIYELTGTVDADRLA
                     GAWRTVIARQPALRSGFVWEGVSEPVQVVLADVDVPLQLRDWSGLDGDTQQERLRELLA
                     QDRALGFDLAAPPLTRLYLVDRGCGQYWLVWGLYQGLCDGWSLPVVMDEVSAVYQGEAL
                     APVRSYREFIAWLDRRDPAEPERFWRTYLDGFEAPTPLPVDRLASSHYAQDRRRTALSA
                     DVTAKIVDLARRERVTLSAVVQAAWAKVLSASSGEDEVVFGLTVSGRPPELAGVESTVG
                     LFINTLPVRA"
     CDS_motif       24516..24632
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0017"
                     /evalue="2.60E-12"
                     /label="C2_DCL_024-062"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1544"
                     /protein_start="1505"
                     /score="39.0"
                     /tool="antismash"
                     /translation="LYWGQGIYELTGTVDADRLAGAWRTVIARQPALRSGFVW"
     CDS_motif       24861..24914
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0018"
                     /evalue="8.50E-07"
                     /label="C3_DCL_135-156"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1638"
                     /protein_start="1620"
                     /score="21.6"
                     /tool="antismash"
                     /translation="LCDGWSLPVVMDEVSAVY"
     CDS_motif       25146..25199
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0019"
                     /evalue="2.10E-02"
                     /label="Cy4"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1733"
                     /protein_start="1715"
                     /score="8.0"
                     /tool="antismash"
                     /translation="RVTLSAVVQAAWAKVLSA"
     CDS_motif       25218..25310
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0020"
                     /evalue="4.30E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1770"
                     /protein_start="1739"
                     /score="60.9"
                     /tool="antismash"
                     /translation="VVFGLTVSGRPPELAGVESTVGLFINTLPVR"
     CDS_motif       25365..25481
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0021"
                     /evalue="1.30E-16"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="1827"
                     /protein_start="1788"
                     /score="53.0"
                     /tool="antismash"
                     /translation="NQVALQRFECSPLVDVQRWSAVPAGRALFDSIVVLRNYP"
     CDS_motif       25983..26018
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS25175_0022"
                     /evalue="1.90E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="C8D88_RS25175"
                     /protein_end="2006"
                     /protein_start="1994"
                     /score="8.8"
                     /tool="antismash"
                     /translation="GVLRSGGVYVPV"
ORIGIN
        1 agcaggcgga gaacgacttc gtgggcgcgc cgaccgggtt gctcgaccag acggcgtcgc
       61 tgtgttgcac ggacgcccat gtgctgttcc tggacgtgcg gtccggcagg caggagcagg
      121 tgccgttcga cgccggcgca cacggcctgg aggtgctggt gatcgacacg cgggtgagtc
      181 actcgctggt cgagtccggg tacggcgaac gccgccgcgg ttgtgagcgt gccgcggacg
      241 tgctcggcgt cgcttcgttg cgggaggcgg ccggggagga agggctgccg gacgagctgc
      301 ggccgctcgc caggcacgtg atcacggaga acgagcgcgt gctgaagacc gtcgagctgt
      361 tgaagcagga gcggtacgcg gagatcgggc cgttgctgag cgcgtcgcac gcgagcttgc
      421 gggacgacta ccgggtgtcc tgcgtcgagc tggacgtggc cgcggaagct gcggagaagg
      481 cgggcgcgct cggtgcgcgg atgatcggtg gcgggttcgg cggatcggcg atcgcgttgg
      541 tgccacggga actccgcgag cgcgtggaga cgggcgtggc ggaagccttt gccgcgcagg
      601 gctttggctc gccgcggatg ttcgccgcgg tgccgtcggc tggggctggc cgggacgtgt
      661 aggtgtcgca ggtcacgacg ggcggactgg gccaagcgta cgcatttgct ggcgctgagt
      721 gatcacgacc gtgcatagtg tccacaggag aatggggact ccaagggggc attgaatgca
      781 catcacatcc ttgtcttgtc gtgcgctcgt cacggtcgtc gcgacgaccg tcgtgaccgc
      841 gctgctcgca cccgtggcgt ccgctgccgc ggactgcacg tggcagcggg agagcctgcc
      901 gatcctggac ggcatgagct ggagcaacat ccggatcacc ggcgtggacg gccagggcaa
      961 cgtcagcggg ttctactcgc cgggcggcga cgatcgcgtg ctggcgcggt ggaccacgtc
     1021 cggtgtggag atcgtgccga agccggaagg cgtcgcgaag ttcgtcacca ggaccggtaa
     1081 cgcatcgggc gtggtcggcg ccatcgcgga ccgttccgac ggcacctccg ttgcgatgac
     1141 ccacacgccc ggttccggct accgcgagct gcccaccccg gccgggtacc gggtctgggg
     1201 agtcgaggac atcaacaaca ggggcgacgt ggtcggccgg gtgaacccga ccggctccca
     1261 cgagtggggt gccgtgttgt ggcgtgccga cggcagtgcg ccggaggtca tcatgccggc
     1321 cggggcgcgc agcgtgacgc ccgtcgccct cggggaggac ggcaccgtcc tgatcgactc
     1381 gatggacggg aacttcctgt ggcgcaacgg tgccctcacc cagttgcccg aggtgcacta
     1441 ctcgctgaac ccgcgcgggc tgacccgtga cggcgtgatc ttcagcagct atgaagagtc
     1501 gtggaagtgg accgaggcga ccggcgcggt cgagaagttc gccgtgaacg gttacgtcga
     1561 ggcggtcaac gacagcgggc tcgccgtcgg ctacctcgac gacgggaact acaccccggt
     1621 cctgtggcag ggcaccgagt tcgtcacccg gctgccgctg tccgccggta cctacggttc
     1681 cgcgggcgat gctgtcagcg acagcggttt cgtcgcaggg gtcgacgcca cgttgccggc
     1741 tcgctgggcc tgccgctgac tctcaccgag gcacgagcac gatccgccca cgcgtggcgc
     1801 cttcggactg acggcgccac gcgtcggcga catcggccag cggcacgacc tcgtggtcga
     1861 cgccgagcgc tccccgtgcc gccaggtggg cgatggtgga aatggcctcc gatcgctgct
     1921 gcgggctgag ttcgttgttc gtgtagccgg acaaccgcaa cgaccggctg cgcaggacgg
     1981 acgacgtgat cgggcacgtc tcgccggcgg agccgcccag gttcacccac cttccaccgg
     2041 ggcgcagtgc ctgcgcggca gcggcggcgg gagggccgaa gagcgggtcg aggacgagat
     2101 cggcgtccgg tgcggcctcg aggaactgcc cggcgaggtc gtcggcgtcc agggcgatca
     2161 cggcgtcggc acccgctcgt ttcgcgcgtt cgcgacccgc ttccgaccgc gcggcagcga
     2221 ccacgcgtcc ggcacctgcg gcacgggcga gctggatcgc ggtctgcccg accgcaccgc
     2281 agccgagcac gatgacgcac tcacccggcg agagctcgcc acgccacgtc agcgccatgt
     2341 gcgcggcgac ggcggagagc ccgagcgcgg ccatcaccac cggcggcacg tcgtccggca
     2401 ggaagaccag atcttgctgc cgcgccagcg ccttctccgc catgctgccg tcgcccgcgg
     2461 ccatcccggc gacggtgggg aaccacaccg cgcgcccgcc gaccgtcccg atcccctgca
     2521 cgccgggaac gtagggtgtc gcgggggagc cgaagtacga ggttcccgtg gcgcacaaca
     2581 ggtccagcgg ggtgatcggg gcggccagca cgtccaggac gacgtgatct tcgagaacgg
     2641 caggctcgtc ccggccggtc atcagcggcg gccggccgag ttgatctacg actgcggcgc
     2701 gcatggctgc aacacgaagt cgtagcgtgc ttccagccac ggcacgtcgc acgtgccgcc
     2761 gtccggagcg ggccccggct cgcgcggttc gaacgcgacg accagctcct gcttggtgcc
     2821 gaacacgacg tcgctgtcga ggtactccgc gccctcctcg aacagatgcg tgatcagcgg
     2881 ctcgtgcccg tcggccgtga cgaggaagtg gacgtgcgcg ggacggaagt ggctgatctc
     2941 cgtctggccg atcagcgcgc cgaccgggcc gtccatcggg atcgagtacc ccttcggcgc
     3001 gatcgtgcgc acgcagtacg agccgtccgg cctggtccgg tacttcgcgc gcagccttgc
     3061 ctcgtcgacg tctggcagct gggcctcgta ggcaccctcg gcgtcggcct gccagacgtc
     3121 gagcaccgcg gcgaccggtg cgccgtcgag cgaacggacg gttccggtga tgtagagcgg
     3181 agttccgtcg acgtcgtcgg acatgtcgcc gccgaagccg agatcggggg agccctcgac
     3241 gtggaacggg ccgagcaccg tcgccggtgt cgcggccggg tcgaagcggt ggttcatctg
     3301 cacgaccagc atgctcagcc cgagcacgtc ggaggcgagg atgaactcct cgcgcttgtc
     3361 gtcgctgatc tgcccggtcg cggtgagcca cttgaccgcg gccatccact cgtcctcggt
     3421 gagcctgacc tcgcgggcga agtcgtgcag gtgccggacg agcgcggtga tgagctgcgc
     3481 ggtgcggggg tccttcgcgg tggcccagcg ctgctccgcc agtgcggtga tgttgtcctc
     3541 ggtgaccagc tgcattgctc attcctccag cggcgcgacg gaccgcgtgt tcgagtccac
     3601 ggacaggaag atctggttgg cgacggggtg tcgcagctcc tcggcgagct ggccgatcaa
     3661 cccggcggtg cgggcgagca acgcgaagcc gcgcaacagc tccagcggca ggcccagatc
     3721 cgccagcacg gcaccgcacg tgccggcgcc gttgagcggc agggtcttcc cgagcacctg
     3781 cgggtggacc ctgccgatcg cggcgaagag cgacaggtgc gggccggtca gtccttcctc
     3841 cgccgcgatc tggaacaggc gcggtgtgcg tggatcgccg ttcttgtgca cgtggtgacc
     3901 gaggccgggg attcgggctt tcccctgtgc ccgcacggtt tccagcgcga gcgcgtccca
     3961 gccggcctcg tcttccggca gctgcgcgga gctgacgacg tcgtgcagga accgtccgca
     4021 gtcctcggtg acgccgagaa accgggagcc gccgccgagc aacccggccg cgagcgcgcc
     4081 ctgcaccgag tcgggcgcgg agaggtaggt gaggcggctg acgatcgcgg tcggagtgaa
     4141 cccgtggtcg gcgagcgcgg ccagcacggc ctcgaacagc cgtgtctcgc ccgcgctggg
     4201 cctgcgctgg gtggccagcc agaacgcgag ctcgccgaac ccgacggtgc ccatcacgtc
     4261 gttcgccagg tcctgtccca gcagcgtgat cgtgtcggga gtcgacgcgc cgagcgcggt
     4321 ctcgtagtga tcagccacgg tcctccttca gccaggcacg cagttcgtcg ccgtgctcgt
     4381 ccagctcggg cggcggcagt ttgtacacgg cgggtgtctc cgagaaccgg atgggatgcc
     4441 gggtcgtcgg cacgtccccg accacgacga caggatccag cccgaaccgc tcggccatgg
     4501 cgaacccgcc gtcgatcgtg ttgatcggcc cgcacggcac gcccgccgcg acgagcaggt
     4561 cgaaccactc gacggcaccg cgggtgcgca gccgatcgag gaggatcggc cggagttcct
     4621 cgcggttgcg ggtgcggtcg gcgttgcgcg cgaaccgcgg gtcgtccgga acctccggca
     4681 gtccgagcac ctcgcacagc ctgcggaact ggccgtcgtt cgcggccgcg acgatcaggt
     4741 cgttgtccgc ggtgggcagc ggctcgtagg ggaacacgct ggggtgcgcg ttgcccatcc
     4801 ggaacggcac gacgccgccc gcgacgaacg ccgagctgtg gttcaccagt cccgtcaacg
     4861 ccgacgacag caggttcacc tccaccagct ggccctggcc ggtggcgtca cggtgccgca
     4921 gcgccgcgag aatgccgatc accgcgtggt tgccggccat gacgtcgaac accgagatgc
     4981 ccgcgcggta gggcggcccg tccgggtcgc ccgtgaggct catcaggccg gagatcgcct
     5041 gcaccatcag gtcgtagccg ggcacgtgcc ggccgtcgcc agagccgaag ccggtgatgg
     5101 acgcgtagat cacgcgcggg ttcgccgcgc tgacgctggg gtggtcgagg ccgtacttgg
     5161 cgaggccacc cggtttgaag ttctcgatca gcacgtccgc gcgccgggcc agctcgcggc
     5221 ccagctcggc gtcggcctcg tcgcgcagat cgagcgctat ggaccgcttg ccgcggttga
     5281 tgccgaggta gtaggtcgag acgtcgtcgc gcacgggcgg catccacgtg cgcgtctcat
     5341 ctccttgcgg gccttcgacc ttgatgacct ccgcgcccat gtcggccagc agcatggtcg
     5401 cgtacggtcc cgcgagcacg cgggagaagt cggcgacgag cagtccttcg agtggtcccc
     5461 cgggcatcag acggatgtcc tggtgtcgcc gcggtactcc gtgtacgtgt aggggttgtc
     5521 cagcaccttc gcggtgggga tgtccgggtt catgcccttc tcccacgcct cctcgccgag
     5581 ctgtgcgcgc aggtgctcga cggtctgctc gaccgccgcg cggatggctt tgaggtcgac
     5641 gccgatcagc cggtggtcgc gcttgacgat ccgcccgtcg acgatcaccg tgtccacatc
     5701 ggaccgttgc gcctggaacg ccacgtggcc gtaggggttg agcaccggga acatggcggg
     5761 tgagttgtcg ttgcgcagca ggacgatgtc ggccttcttg ccgatttcga tgctgccgag
     5821 gtcgtcacgc cccaacgctt tcgcgccgcc catggtcgcc cactcgacga cgtgctctgc
     5881 ccgcaacgac gagtgcgtga ccgtctcgtt cttggcgtgt gccgccatgt gttctcttgc
     5941 ccggtcggcg cccagagtgc tgcgcatggc ggagaacagg tcaccgctcc accacaccga
     6001 ggtgtccatc gacagcgaca ccgggatgcc gtgggcgcgg atcgcccagg tgggcgggta
     6061 accctggccc gcgctctgct cgctctcggt cgacacggag atggagccac cggtcgcggc
     6121 gatgcggtgg taggagtcgg cggacagcgt cgcggcgtgc acgtagatcg actgcggcgt
     6181 catgaagccg ttgtcgtgca tcaaccggat gccgtcgtcg ttcgtcgcgc cccacacgcc
     6241 cgcgtgggtg gtgacgggca cgcccagttc acgggcgacc tcgaacgcgg gcttctccgg
     6301 gaacgcgggg tcgccggtga cgtcgaacgc gagctggaag ccgagcatgt cgtcgttcgt
     6361 gatgcggcgg ttcacgaagt cgcggaactc gggcttggcg gtccagttcg ccgggctgtc
     6421 ctggatgttg ccgtaggcga gcacgaaccg tccgggtacc tgctgcagcg cgtcgacggc
     6481 cgcgtccgcg tggtcggtcg tctgcagccc gtgcgaccag tcgaccgtcg tggtgacgcc
     6541 ggcgtcgagt gcctcggcgg caccgaggat gttccccgcg tagacgtcct ccggccggaa
     6601 gaccttgccc cactcgaggt agtaccagac gaagtactgc gtgagcgtcc agtcggcgcc
     6661 gtacccgcgc atcgcggtct gccacaggtg ccggtgcgtg tcgatcatgc ccggcaggac
     6721 gatgccgccg gtggcgtcga cctcctcggt gcccggtggc gcctccagcc gcggcccgat
     6781 cgcggcgatc cggtcgccga ccaccagcac gtcgtggtcg gtgaggatcc tcttctggcc
     6841 gtccatggtg aggaccgtgc cgtttctcag gacaacagga cgtcgttcgc cgaccatcgg
     6901 ggacctcctc gaccggcatg cggacaggtg tccgttgaat cctcaacctt caccggtcgg
     6961 ccgtcaaccc cgctcaggcg acgacgatgt gcggcaccgt ggcgagccgc gcgaagtcgg
     7021 cgctgatgtc gccggcggtc tgcaacagca gcggcaggtg gtgctcgacc atgtgctcga
     7081 ccgacgtctc ggacgcgtgg cagttgacgt tgatcccggc gatgaccgtg ctgttcccgt
     7141 cccgcaacgg cgccgcgacc gaccggatcc ccggcgcgag ctgctggtcg gtcaacgccc
     7201 acccgcgcgc ccgcacgtcc ctgagctccg cgtcccgctc ggccgcgccg ggttgccacc
     7261 gcggcgtgag cccggaccgc gtcggctggg cgagcaccgc ttcgagctcc tcctgcggca
     7321 gcgcggcgag ctgcaccttg cccagcgacg tcggcagcgc cgggaacttg gtcccgatct
     7381 gcacggaaag cgtgacgatc ttcggcaccg ccacccgcgc cacgtacacg atgtccgacc
     7441 cgtcgagctg ggcgatcgac accgactcgt tggtccgtgc ccccagccgt tccatgtgtg
     7501 gccgcgcgac ctcccacaac ccggtcgacc gcacgtaggc gacgccgagc tcgagcaccc
     7561 gcggcgtgag cgcgaacccg ttctcgcact gccgcgcgta cccgagctcg atgagcgtga
     7621 gcaggatccg ccgcgcggtc ggccgcgcga gcccggtggc cgccgcgatc tcgctgagcg
     7681 gcatcaccgg gcgcaggggc tggaacgcgc ggatcacgtc caggccgcgg gcgagcgcct
     7741 cgatgaagtc ggggccggtg tcgggtcgcg cgggcatagc gccagcgtag cggacacttg
     7801 tccgctgatc ggctcaagac ctgctgatca gctgcgtcga acctgaccgc tagctctcga
     7861 accggccgtg cctgccctct ccagcggtga accgggcagc accggacgcg ccttcgcgtg
     7921 ccacgatcgg caccccgccc acgccctcgg cccgcagcgc ctccgccagc ggcaggtcga
     7981 gcccggcgta ggtggacgcc cggtccgcga gcacgcactc gaacgggaac ccggcgatct
     8041 gctcggccag ctcgatcgcg gccggcaccg cctgccccgg ctcgaccacc cggttggcca
     8101 gcccgatcgc cagcgcctcg tcggcgtgca ccggacgtcc ggtgaggatc aggtccagcg
     8161 cccggcccag ccccacgatc ctgggcaggc gcacggtgcc gccgtcgatc agcggcactc
     8221 cccagcgccg gcagaacacg ccgaacaccg cgtcgctctc ggccacccgc aggtcggcga
     8281 gcagggccag ttccagcccg cccgcgaccg cgtggccgct gacggccgcg atcagcggtt
     8341 tgctcggctg cagcctggtc ggacccatcg gccccgcgcc gtcggggtcg aggtcgttgc
     8401 ggcgcgcggg atcgttgacg gaggtcagat cggcgcccgc gcagaacgtg ccgcccgcgc
     8461 ccgcgagcac cgccacgcgc tgggtctcgt ccgcctcgaa cgccaggaag gcgtcgcgga
     8521 gccggcgggc catcgggccg tcgaccgcgt tgcgccggtc agggcggttc atccagatca
     8581 ccgtggtggt gcccgtcgtc tcgacccgca cgtcgtccat ccgcgcctcc tcggcgaaat
     8641 ccggctggtc agcgtcccgt caggccgacc gccagcgtca gctccagaac ccgttgcggc
     8701 gaaccgagat cgggaaacag ctcacgcagc tgcgacatcc ggtaccgcac cgtctgaggg
     8761 tgcacgaaca acgccgtcgc cacctcctcc cgccgcccgt gatgcagcaa ccacgcccgc
     8821 aacgtctcct ccagccggcg agcggtgctc gccgacaacg tgcggagcgg tgcgagcgcg
     8881 cgggctcgga ggtccgcgta cgcgtcgggg tcggcgctca gcaccagctc tggcaggtgg
     8941 tcctcggtat cccggatgtc gggggagagg gagcgcgcgc gtacggctcg tgcgtaggag
     9001 gcagacgcac gggtccatgg gcgcgccggg ccgacgacgg cgttgcgacc cgtcagctgg
     9061 cgtagcaggt gtgcgcggtc ggcgtcgggc accagcagca cgccgagggc gtccggcagg
     9121 tcgtcgagga ccagggtgct gggatcgagc gagcggtacg cggggcgagc ctgggcggcg
     9181 ggcagcagaa cggcggtcag cgacgtgggc ggttgccagc cggctcgctg ggcggcggcg
     9241 agcaggacgt cggcgcccgc gcccgccagg aggtcgcggg ccagctgttc caggtgacgc
     9301 tcatgggcca ggcctcgtgc ggccagctcg tcggcgtggc ccgcggcgct ggcggcggag
     9361 agctcgtcga tgtaggcgaa ggtcagctcg gcgaacttcg ccacctcctc ggccgggagg
     9421 cccgccgaga ccgcgcccgc tgccaggccg cgccacgcca cgcgcgcgcc gacgcggtag
     9481 gcactcagca gggcgtccat cgagcggccg tcgcggacct cgccgcggcc cagctcgtag
     9541 gccgcatcgc ccgcgtcgac accggtcgcc aggccgcccg cgaggtcgag gtagtgtccg
     9601 agcgccgtgc ggacggcgcg gcggatggtg ccgcccatgc gtccggtcag cgcgttggcg
     9661 tagctcggaa cctcgtcgat gatggcctcg acgacctcgt cggcggtggt cttcagggcg
     9721 gccctgagcg ccatgaccgt cgtctcatcc agggccagtt cggtggccct ccgcattgca
     9781 tgactcacga tttgttccct gcgaacaatc cagccgggca gattcacgtc ctgcggacag
     9841 gactttacgc cctgaggcgc atcaagctgg agtcatgacg agtgccgccc tccgcagcag
     9901 ggcgtggaaa ctgctggaac tggtcacgac gccgctgctg ccgtcggact acctcgacct
     9961 ggtcagcccg ctgcgtgcgg gcgctgacct gcgcggacgc atcgaggccg tgaacaagga
    10021 gaccgccgac gccgcgacca tcgtgatccg gcccggacgg ggctggcgcg gccacactgc
    10081 cggtcagtac atccggatcg gtgtcgacgt cgacggggtg cgcctgtggc gtgcctactc
    10141 ggtgacatcg ccctcgaacc ggacggacgg ccgcatcacc atcacggtga aggccatccc
    10201 ggacggcaag gtcagcaacc acctggtccg caaggtcaag ccgggcacgg tgatccagct
    10261 cgaccaggcc tgcggtgagt tcgtgctgcc gaagaccaag cctgccaagg tgctctacct
    10321 gacggcggga agcggcatca cgcccgtgat gggcatgctg cgcgacaccg agctggccga
    10381 cgccgtcatg gtccactccg cgccgcgcca ggaagacgtg atcttccgca acgacctgca
    10441 cgacctcgtc gcggacgaga agctgcggct cgtcgagctg cacaccgaca cgcacggcat
    10501 gctcgacgtc gcccgcctcc acgagctggt gcccgactgg gccgagcgcg agacctgggc
    10561 ctgcgggccc accggcctgc tcgacgcggc cgaacagcac tgggccgagc acgacctggc
    10621 cgaccggctg cacaccgaac gcttccgccc cagcgtggtc gtggcgggcg acggtggcga
    10681 ggtcacgttc agcaccacgg gcaagaccgt cgacgccgac ggcgccacgc cgttgctgga
    10741 cgtcggcgag ggggccggcg tgctgatgcc gtccggctgc cgcatgggca tctgcttcgg
    10801 ctgcgtcacg cctctcaagg cgggcgccgt ccgcgacctg cgcaccggcg agatcaccga
    10861 ggccgagccg ggcgtcctca tccagacctg tgtgtccgcc gcggcgggcc cctgcgacat
    10921 cgaacgctag ccccgcgcgg gcaccctcca cccctcgact ccccccgcga aagcgagcta
    10981 catgagcgcc atcgacccca ccgcccacct gaccgccgag cagatcgagg agctcggccg
    11041 cgagctcgac gcgatccgcg acgaggtgat gtccagccgt ggtgagaagg acgccgccta
    11101 catccgcaag gtcatctcgg tgcagcgcaa gctggagctg gccagcaggg gcgtgctgct
    11161 gttctcgatc ttcccgcccg cgtggctggt cggcaccgcc ggcctgtccg tggcgaagat
    11221 cctggagaac atggagatcg gccacaacgt cctgcacggc cagtgggact ggatgcgcga
    11281 cccgaagatc cactccacca cctgggagtg ggaccacgtc tcgcccgccg agcagtggaa
    11341 gcactcgcac aacgagctgc accacacgta caccaacgtg atcggcaagg acaacgacct
    11401 cggctacggc atcatgcgcg tcgacgagga ccagaagtgg cacccgatgc acctcggcca
    11461 gccgctgtgg aacttcatca acgcgtgctt cttcgagtac ggcatcgccg cctacgacct
    11521 ggagctcggc aagaacctgc acaagcgccg ccgcaagaac cccgagttcc gcgcgcgggc
    11581 caaggcggtc ggccgcaaga tccgccgtca ggtgctcaag gactacgtga tccacccgct
    11641 gctgtccggg ccgtcgttcc tcacgacgct cgccgcgacg ttcaccgcga acctcgtccg
    11701 caacctgtgg tcgcactcgg tgatcatgtg cggtcacttc ccagagggcg tgcaggtctt
    11761 cgagcgccgc tcgatcaagg gcgagacgcg cggccagtgg tacctgcgcc agatgatggg
    11821 ttcggcgaac atcagcggca gcaagctgat gcacatcatg accggcaacc tgtcgcacca
    11881 gatcgagcac cacctgttcc cggacctgcc gagcaaccgc tacgccgagg tcgcggtgaa
    11941 ggtgcgtgcg ctgttcgaga agtacgagct ggagtacgtc accggctcga tgcccaagca
    12001 ggtcttctcc gcgtggcaca aggtcttccg gctctcgctg ccgaacaaga agcctaagac
    12061 gaagaccccc gcccgcgaca aggagctcgt cgccgcctga aaccggtaat tgttcagacc
    12121 tttcggccgt accggtgaca tcgccggatt cggtgagatc cgttcgaggg gcccgattcc
    12181 ctacccctgc tgctggaccg ggccctccaa acggaggatc tcatgcgaag ggtcaacctc
    12241 gtcgcggcca ccctgctgac ggtcgcgacg atcatcacgc ccacctctca cgcggctcct
    12301 gccgcgatca ccggatcgcc tcgaaccgcc cctcgacccc gctcaccgcg ctgctcgtgg
    12361 actacggccc gagcacgcag gccgtgctca ccgaccgctc gccactgcag ctgtccacgg
    12421 aaacctgcac ccgcacggac ctgcgtgagc gcaccggctg cgcccgccgg ccggccgtct
    12481 ccgtgcaggc ggtcaccgcg acgatgctga cccgcggcgc gatcgacgcg aagaaccgcg
    12541 agtcgctgga gtcgtcgact cccttgcccg ccaacgcgac tgcggacgtc acctggcggt
    12601 tgcacgccag ggacgcggtc atccctgccg ggcaccgcat cggcgtcgtg atcgtgacca
    12661 accacggtgg ctacatcaac caggacaccg gggccaacgg gatcgcgctg caggtgtcgc
    12721 tcggtgccag caaggtcgtg ctgccgatcg tcgggggagc ggtgatcacc tgaccgttgc
    12781 cggccgttct gggcgcctca acgcgactcg ttgaggcgct ccacgggccg gtcggcgcgg
    12841 ctgcgggaga accgcagctc gtcgtcctca acaggcaggc gccgcaacag cttcacgtcg
    12901 ctgaagtagc tcatcgaggt gagccacggc gcccgctcgc cctggcgcgg cagctggtcc
    12961 aggacgcgcc tgacgtatcc cgcgccgaag tccaggaacg ggcgggtcgg cgcaccggga
    13021 tcggccacca cggggcgggc cgtgtcgtag ccgtgctcgt ccatgtgggc gagcagccgg
    13081 cagaagtgct cgcacagcag gccgaccttg agcgtccacg acgagttcgt gtagccgatg
    13141 gcgtaggcga agttcggcac tccggacagc atcatcccct tgtacgccaa ggtgtccggg
    13201 aggcgcaccg gctctccgtc gacggtcagg gtcattccgc cgaacgcctg gacgttgagg
    13261 ccggtcgcgg tgatgacgat gtcggcttcc agcgtgcggc cggactccag cagcacgccg
    13321 gtctcggtga acgtggtgat ccggtccgtc acgacggatg ctttgccgct gcggatcgcg
    13381 gtgaacaggt cgccgtccgg gaccacgcac agccgctggt cccaggggtt gtacggcggg
    13441 ttgaagtgtt cgtcgaccgg atagccctcg ggcagcagcc tggcgttgaa ccgccggatc
    13501 agccgccgcg ccgcgttcgg gaaccgccgc gagaaacgcc aggtcagttg ctgctgcagg
    13561 atgttcttgc ggcgcatgat cgcgaacgag cgctcggggc tcagcagctt gcgcagcgcg
    13621 ttgccgatcg gatcgcgggc cggcaccggc agcacgtacg tcggggtgcg ctgaagcatg
    13681 gtcacatggc cggcggccgg ggccatggcg ggcacgatcg tcaccgcggt cgcgccgctg
    13741 ccgatcacga gcacgcgctt gcccgcgtag tcgagatcct ccggccagtg ctgcgggtgg
    13801 atcagctgac cgcggaagcg ttccctgccc tcgaagtgcg gtgtgaagcc ctcgtcgtag
    13861 cggaagtagc cgcccgcgca gaacagccac gagcacgtca gcgtctcgcg ttcgccgtcc
    13921 ttctcgacct ccaccgtcca gtgcgcgtcc ggcgacgacc actcggcggc gatcaccctg
    13981 gtgtggaacc ggacggcacg gtcgatgtcg tgttcctccg ccgtctcgcg caggtaggcg
    14041 aggatcttgt ccgcagcggc gatcgagtcc tcgtcgcgcc acggcttgaa ctcgtagccg
    14101 aacgtgtgca ggtccgagtc cgaccggatg ccggggtagc ggaacaggtc ccacgtgccg
    14161 ccgatcgccc cgcgtgcctc gaggatcgcg tacgtcttcc gcgggtgttc gcgctgcagg
    14221 tagtacgcgg cgccgaggcc ggagatcccg gcgccgacga tgaggacgtc gaggtcagcc
    14281 atgtgttcat ggtgaccggg gtgacgccgg tcacgaaagc acgaagtgca cctgttcacc
    14341 agttctgtgg tgcaatctgc accatgtcgt gggagcgtcc gtcaccgcgc gtgcgtgagc
    14401 tcatccggcg cggcgcggag atcgcgctgg atccgcccgc cgagtggctg gccgagctgg
    14461 acaccgcgac gctgtccggc ccgaaccgcc agcaggtcgc cgaggatccc gtgctcgccg
    14521 ccgcgctgaa gcgcacgaac cggtcgaacc tgctgggctg ggcgtcggcc aacatccggg
    14581 cgccggggga acgcgtgccg gcggacctgg gggaggcgcc gctggcgttc gcgcgcgacc
    14641 tgatccggcg cgggctcgac gagtcggcgc tcgacgccta ccgctccgga cagggcgtcg
    14701 cactgcggct gtggatgcag atcgcgttct cgctgacgtc cgaccacgag gagctgcgcg
    14761 agctgatcga cgtgtcgtgc cggtcgatct cggcgttcgt cgacgacacc gtggccgcgg
    14821 tctcggcgca gatggcgcgc gagcgcgagg agctcacacg cggcacgcac gccgaacgcc
    14881 tggagacggt gacgctgctg ctcgacggcg cgccgatcac cgtgtcccgt gctgagcaac
    14941 gcctcggcta tcggctctcc ggggaccaca cggcggcgat cgtgtggagc gacgacgcgt
    15001 tgggcgacct cgaccgcgtg gccgacgtgc tcgcgacggc cgccggagat ccgcgtccgc
    15061 tgaccgtgct ggccagcgcc gccacccggt gggtgtgggt gcacggcacg ccggacgacg
    15121 ctgtgctccg cgccggcgtc gcgcgattcc ccgccgcgcg ggtggcgctg ggatcgagcg
    15181 gttctggcgc ggacgggttc cggcgcagcc acctcgacgc gctcacggtc cagcgcatgg
    15241 tcgcgaggct cgcgtcaccg caacagctcg cgacgcacga ggaggtcgag ctcgtcgcgc
    15301 tgctcaccac ggacgccgag cgagccgacc ggttcgtcag gcgcaccctc ggcccgctcg
    15361 cgacggccga tccggaggtg accgaagccg tgcgggcgtt catcgccgcg agctgcaacg
    15421 cgacgacggc ggcggcacgg ctctacacgc accgcaacac cctgctgcgc cggctggcgc
    15481 gcgcgtccaa gctgttgccg cggccgctgg agcacaacct ggtgcacgtc ggcgtcgctc
    15541 tggaggtaca tcggtggcgc gcacagtgac gcagatgacg agcaggaatg cccgtgcgcc
    15601 ctgttgcgtt ccgcaggaca tgaagaagat cgggttcctg tcgttcggtc actggtcgga
    15661 cagcccgcac tcgcagacga ggtccgcctc ggacacgctg ctgcagtcca tcgacctggc
    15721 ggtggccgcg gaggaactgg gcgcggacgg cgcctacttc cgggtgcacc acttcgccca
    15781 gcagctcgcg tcgccgttcc cgctgctcgc ggcgatcggc gcgaagacgg agcgcatcga
    15841 gatcggtacc ggtgtgatcg acatgcggta cgagaacccg atgtacatgg ccgaggacgc
    15901 cggcgccgcc gacctcatcg cgggcggcag gctgcagctc ggcatctcca ggggatcgcc
    15961 cgagcaggtc atcgacgggt ggaggcactt cggctaccag cccgcggagg gggagaccga
    16021 cgccgacatg gcccgcaggc actccgaggt gttcctgaag ctgctggagg gcaagggttt
    16081 cgcgcggccc aatccgcggc cgatgttccc gaaccctccc ggcctgctgc ggctcgagcc
    16141 gcactcgccg ggcctgcgcg accggatctg gtggggcgcg ggttccaacg gcaccgccgt
    16201 gcaggcggcc gagcagggca tgaacctgat gagctcgacc ctgaagttcg acgagggcgg
    16261 ggcgcccttc cacgtgcagc aggccgagca gatccgggcg ttccgcaagg cctggacgga
    16321 ggccggccat ccgcgcgagc cgcgggtctc ggtgtcgcgc agcatcttcg cgatcaccac
    16381 cgacctcgac gacgcctact tcggaggtga gggcgagagc accgaccagg tcggcttcat
    16441 cgacggcccg aacagggcga tcttcgggcg ctcgtacgcc gccgaacccg aggtgctggt
    16501 cgagcagctg gcaggggacg aggcgatcgc cgaagccgac acgctgctgc tcaccgtgcc
    16561 caaccagctg ggcgccgact actgcgcgca cgtcatcgag aacatcctcg tgcacgtcgc
    16621 gccggcgctc ggctggcgct gaccggcgag cccggccagc gctagcgctt cacggcggag
    16681 aagcgggtca acgagctgcc gcgaaccccc gcggtgaccg gcagctcggc gaacgcctca
    16741 cgcagttcac ccggcctgat catggtcgcg gtgccgagcc cgagcagctc gaccgggcgg
    16801 gtgcgcacga tgtcgtagcc gacgaaccgg ccgccgggcc gcagcacgcg cacgacctcg
    16861 gccagcgccg cccgccagtc gccgacgtgg tgcagcatcc cgcaggacag caccgcgtcg
    16921 aaccggccgt cctcgaacgg caacgccgtg gcgtcggcct gccgcgcggt cgcccgtgcg
    16981 ccgaacggtg cgaggactcg ctgagcggac tcgaccatcc gcgggtcgaa gtcggtcacc
    17041 acggcggtga ggtcgccgtg gcgggcgagc agctcggcgg acatggcgcc gctacccgcg
    17101 ccgatctcca gcagggatcc ggcgggccgc acctgaccca gcacccacgg cagcacgatc
    17161 cggcgcgcgg ccagccggta gacgccgctg acgctgacgg accgcaggac gttcgacatc
    17221 gaggccatgg ctcactccgg aggtcggttg taggactcct tgcggttcag cgagttgcgg
    17281 accttgactc tggccaaggg atcagtaggg gccgacgagc cggtacttgg gccacagctc
    17341 ggtccacggt gcccgcagac cgcggcacac cgcgacggac cggccctgct ccctggtctc
    17401 cagcccgtac ccgttgtcga tacgcgccac caccgagcac tcgcggaagt cacgcgtcag
    17461 ccgttcgtcg tccacggcca ccgtgatcac cacgtccgcc gtctctggcg gcggacccca
    17521 cgagtacagc tcgttgtgtc cgctgtagac ccgagggagc gggcggtcgt cgtgcagcca
    17581 gcgcagcgcg cccgcttcgc cgaagttctg caccagcacc acggcgcgtg atcgctcgtc
    17641 ggccggcagc tcggcgtagg cgtcggtgac ctgcccgacc agccggggcc agccgatggt
    17701 ctcggtggtc aggctggtcg tcgggtactg cgcgtacatc cgttccggca ccaccggcag
    17761 ggtcatcacc acctggccca aggcgaacag cgacagcacc gacaccgcca cgggcaaacg
    17821 caccgggtgc tgggccagcc atccgtccgc gaccacgcat cccgcggcga cgagcggtac
    17881 caggtagccc tcggtgtagt cgatgccgct cggtgcgacg acgagcacca gtgccgtgcc
    17941 gacgaggtag gccacggcca gggtccgcgc cggccgccag ccctggcggc gcagcaggct
    18001 gaccaggcca gccagcagga tcggggccac cgccggcccg atcaggactg ccacgtcgaa
    18061 ggggaacagc gccgcgtccg accactggcc ctcagccagc gatcgcgcca tgacgagctg
    18121 cggccagccg ttgaccgcct ggtagaccag gttcggcgcg ccgatcacca gggtcagccc
    18181 ggcaccggcc cacagccagc ggctgcgcag ttcccggcgc ggccccacca gcaccagcgc
    18241 gaccagcagt gtcagcggca gcaggagcac gacgtacttg gcgtacgtcg ccaccccgca
    18301 cgtgacgccg gcggccagcc accaccggcc gtccccgcgc agcagtgccc gcagcgcgaa
    18361 cagcgccacc gcgcaccagg cgaccaggtc cgggctgttg gtcagcagga agtgcccgat
    18421 ggtgagcacg gtgaccgacg tggccactgc cgctgccgcg agcacctgtg cgcgtcgccc
    18481 accgcccagc tccgcggcgg tcagtgcggc gagcaccacg accgccacgc cgcacagcac
    18541 ggccgggagc cggatgcccc agatcgtgtc gcccagcagc aacgcacccg ccttcgcgag
    18601 cagcggtgcc agcggtggct ggtcgaagta gccccagcgc ggcacgtcac ccagcagccg
    18661 gaagtacagc tcgtcggccg agagcccgta gttcgcggct accgcgaaca tcagggccgc
    18721 gtagagcgcc gcgaccactg ccaccggacg ccgggccagc ggcacggcca caccggtccg
    18781 cgttgccatg ccctccgctg tcaacaccaa cgctgctccc cctcctggtc gcggacgatc
    18841 gaccgaggcc agcctcgtcc gcaacacgaa cgtcacgccg cacaggtgtg gtgatcccag
    18901 gtcgccggca actggccgat cacgttgttc cgggacaccg catttggcga tgctatcgac
    18961 atgatcggct cggcttattg ctccgatcgg cagcaatcgt ccccagttgc ggcattcacg
    19021 actggacgat tgatagccga tggaaagatc ggcggtcggc ttgtagcaca tcgcggaggt
    19081 gtgccgcgga gggttgaccg tcgaatgctg agcggaagtc tcggaaacga aagatgaccg
    19141 cgggggtcgc caatagcgca ctccgggcag aaatgtggcg cgttggcgcg acttggtcag
    19201 cgcggtggcg cggatacgcc caaaggctgg ccgactcgcg ccatcgacca gtcgagtcgg
    19261 tggaaggagc tgcttcagag ttccacccgg cctttgggtt gttttagagc agccttaaag
    19321 tcggtaattg aaattttgtc atgtttgctc gctgacctgc ggggtctacc ggaatgtggg
    19381 cgcgctccca gtcctggtca gggggtggcc agggtgccgg tgttgatcac ggcgtgtgtt
    19441 tgcgcaggtg caacaggtga cggaaggcgc ggtgccgaga tagttggttg atggtttgtc
    19501 gaaatgcgta gtgcaccagt tcgactgttt ggtggattcg tgtgtgttgc aggtgtggct
    19561 aatctgcggt cagtcgcttc aagcgacacg ggggttagtg gtgtggtcgc tccggtggct
    19621 ggctgattca cgtgtgggtg cggtgaatcg gtgagttggc ggatcacgca gggggtgtca
    19681 tggcggttgt acgtgaattg gtgctgaagt cgcccgcggg ctggatgtcc gtgagtgcgc
    19741 cgatcggcgg ccctgccggt tgtcgtccca gctcgcgtcg gtgaaaccgc acatcgccca
    19801 gcgctgccca ctgattggtg cggctcggac gcggtactcg taattcacca ctgtcgcggc
    19861 ggcgttcctc gatccgctgt atctgcgact tctgcagtct cactgttccg ctgtggcgga
    19921 acggtttcgc acgtcccgtc acagcggcac gccaagccgg ttcgtgagtg gcgggggcat
    19981 cggtaagggg gagcggttct gtggttggac ggcgtgagcc tggcgttcgg tactcgctga
    20041 ccgcggcgca gctggacatg tggctgtcgg ctgagctgct cggggacacc ccggagttca
    20101 acccggccca gtacgtggtg ctccgcggac cggtcgacga cgagctcctg cggggcagtg
    20161 cgctggtggc ggccagggaa accgacgcct acaggctgtt cttcggcgag cacgcggacg
    20221 gtgcgccgtg gcaggcgctc gccgacggac tgcctgccga cgtgatgccg gtggtggatc
    20281 tccgcggtga ggatgatccg gcggctgcgg ccgcggcgtg gatgcacgcc gacggcgccc
    20341 gcccgatcga ccaccgggtg gcgccgctgt ggcgttgggc gctgctgcgc gtcgccgccg
    20401 acgagagctg gtggtaccac cggtcgcacc acctgatctg cgacatcttc tcgttcaacc
    20461 tgctcacgca acgcgtggcg gagatctaca gcgctgcgca ccggccccgc tacttcggct
    20521 cctgggccga tgtcgtggcc gaggaccagg cctaccagcg gtccgccgac cgggtcgccg
    20581 acgagcggta ctggctggac tcggtcgcgg aagcggtgca aagccgccag gacgaacacc
    20641 gtcccgagcg gcagcggccg tcacggcggc gcacggtcgc ggtcgacgcg gcgttgcgcg
    20701 gcgccgtcct cgatcggtgc gccgacctgg gcctgcgcgt cccgcacttc ctcgttgcgg
    20761 ctttcgccgc ctaccagcgg cagctgacgg accgggacga cgtgctgttc agcctcccca
    20821 cggcagcccg gcgcagcctg ctggcccgca gcaccccggg gttgctggcc aacgtcgccc
    20881 ccgtcgtcct gcacctgccg gacggcacga cggtccggca gctgaccggc gccaccaccg
    20941 cgcggctggc cgagatcacc gccaggtcgc gctaccgggg cgaggacctg gcccgcaagc
    21001 tcggggtcgc cggcaacggc gcgtggttcg gtcccgtgct caacgtggtc gacttcaacc
    21061 ggccggtgcg cttcggcgcg gccgtgcagg ccgacgtgcc ccgcaacctg tcggtcggtc
    21121 cggtccgcga tctcaccgtc accacctacg gctggtctcg tggtgatcac tcgtggctgg
    21181 acatcgacgt cgaggacggc gtggccgccg gtgccgagct ggcactgcac gaggagcggt
    21241 tcctggaact gctcgaccgg cttgcccgcg gaccggtgga cggtgcgacg ccgtcgtcca
    21301 ctgtggactt gcggctcacc gggcagtggg gagcgggggc ggcgccaggt gcgaccgcga
    21361 gcgtgcccga cctcatcgcg agccacaccg tcgcctggcc cgaccggacc gcggtcgtgt
    21421 gcggtcagga ccaactctcg ttcggcgagc tcggaaagcg cgccgacgca ctcgccgtcc
    21481 gcctgcggca ggtcggcgtg accgtggagt ccgcggtggc ggtgctcgtg ccgcgtgggc
    21541 ttgagctggc cgtcgccttc cagggtgtgc tgcgcagcgg tggcgtgtac gtgccggtca
    21601 atcctgggct gcccgcggaa cgcctggcgt tcctgctggc cgacgtcggc gcgacggtcg
    21661 cggtcacgac tgcggctctg gccggcgagc tggcggggtt cgcgggcgaa gtgctggtgc
    21721 tggatgactc ttctccggct gctgacgcgg cgctggtgcg catcaacccc gatgcgctgg
    21781 cgtatgtggc ctacacgtcg ggctcgacgg gacggccgaa gggtgtggcg gtcacgcacg
    21841 ccgcgttgtc gtcctatgtg gacggctggc ggcaggcgct cgctccgctg ggcggggcgg
    21901 gcaccgtgct gtcgatgtcg ggtcctggtt ttgacgtgtc catcggtgac atgacccgtg
    21961 ctctggcatt cggtcagacc gtggtgttcc tgccgcacga cgaggccgtg tcggtcgact
    22021 ccctgcaccg cacgctggcc gaccacgagg tcgagatcgc cgagatcgtg cccggcatgc
    22081 tcctgcgcga tctcgccgct cactgccgtg cggcgggtcc ggtcgagtcc ctgcgcctgg
    22141 tgatctcggg caccgacatg tggacgtacg acgcactcgt gtccgcggtc gcggccgtgg
    22201 cgcccaacgc cgtgcccggc aacgtcttcg gcgtgaccga ggccgcgatc gactcgatct
    22261 tccacccggt cacggcgcgg ccggagcacg agggcgaggt ggtgccgatc ggcgggccac
    22321 tggccggcgt cgacgcgttc gtcgtcgacg gctggctgcg gccggtgccc gtcggcgtcg
    22381 agggtgagct gctggtcggt ggtgcgggac tggctcgggg ctacgccggg cgcccggacc
    22441 tgaccgccga gcggttcctg cccgatgtgt tcggcggatc cggcggtcgg ttgtaccgga
    22501 ccggtgaccg ggcccggtgg cgtgccgacg gtgtgctcga gttcctgggc cgggtcgacg
    22561 agcaggtgaa gatccgcggc tatcgggtcg agcccggtga ggtcgaggtc gtcatcggcg
    22621 atcacccgga cgtgcgtgat gtcgtcgtgg tggctcggga tggtggcccg cacggcggca
    22681 agcgcctggt cgcctacgtg gtggccgaga accagaacct cgctggtgtg caactgaggt
    22741 cctggttgcg agagcgtgtg ccggactacc tggtgccgtc ggtgttagtg acgctggatc
    22801 ggctgccgct gacgccgaac gggaaggtcg accgccgggg tctgcccgac cccgagcccg
    22861 ggacggccga agcctacgag gcacctcgga cgtccactga ggacgcgctg gcgacggtgt
    22921 ggtcgcaggt gctgggcgtc gaacgtgttg gcgtgcacga caacttcttc gagctgggcg
    22981 gcgactcgat cctgagcctg cagatcgtgg cgcgcgctcg cgccgcgggt ctgggcgtcg
    23041 acgtggccga cgtgctgtcc caccagaccg tcgccgagct ggcggccgtg gtgcgtgacg
    23101 ctcccgcggt gacgacggcc gagcagggtg tggtcaccgg tccggtgccg ttcacgccga
    23161 ttcagcggtg gttcctggct caggacatcc cggaccggga tcactggaac tggtcgggtg
    23221 tgttcgagct ggcgccgggc accgacgccg attgccttgc gtcggccctc aacgctgtgg
    23281 tggcgcatca cgacgcgttg cgcatccggt tcacgccgga gggccagtac aacgcgggca
    23341 ttgagcatgc tggcctgcgt gtcgttgctg tgcacgacga cgaagtgcct gcggagatgt
    23401 cgacggcgca gaagtcgttg cggttggccg atggtccgct cgtggcagcg gtgttcttcg
    23461 accgtggttc gcagcctgcg tggctgggtc tggtcgttca tcacgtggtg atggatggtg
    23521 tgtcgtggaa cgtgttgctg gaggatctcg acaccgcgta ccgctcggag gcgttgggag
    23581 cgaagacgtc ctcgttccag cagtgggccg agcacctgct ggagctggag gtcggcgggg
    23641 aacgggagca ctgggtcgcg gcgacgtcgg acgtggtcgc gctgccggtc gaccacgacg
    23701 ggcccaacaa cgagcgctcc gcccggatcc acacgacatg gctggacgcc gggacgaccg
    23761 ccgtgctgct gggcgacgcg cacaaggcgt atcgcacgca gggcaacgat ctgctgctgg
    23821 ccgcactggt gcgcacgctg ggtccgtggg cgggcaccga tgagctgacc atcgacctgg
    23881 agagccacgg ccgcgagggt ctggatctgt cgcgcacagt cggctggttc acgtcgatct
    23941 tcccggtgcg gttgagccgg cacgctgatc tcggcaccac cgtgaagacg gtcaaggaac
    24001 agctgcgggc ggtgccgcgt cgcggtgtcg gctatggcgt gttgcggtgg ctgcggggtg
    24061 agttggccga tgcgccggat cgtccggtgc tgttcaacta cctgggatcc gccgcgggca
    24121 ccggggatct gctgcgccgc gagctgcccg cgaccctgcg aggtgccgcg acagccggcc
    24181 gcggcacccg gtcccacgtg ctcaacctgg aggtgacccg caccgccggc gggcagctgc
    24241 aggtcgagtg gcactacagc gccgacctgc acgacgcggc gaccgtcgag cggctggccg
    24301 agacctacca gcgggagctg gaggagctgg tcgagcactg ccggtccggg gtctcgggtc
    24361 tcacgccgtc ggacttcccc ttggcgtcgt tggcgcagaa cgaggtcgac cggctcgcgg
    24421 cacggttccc cgagctggtg gacgtgtacc gcttggcgcc cgtgcagtcg ggcatgctgt
    24481 tcggggtcgt gggcgcgcca gccgacggtg acgggctcta ctggggacag gggatctacg
    24541 agctcaccgg caccgtggac gccgaccggc tcgccggcgc gtggcggacg gtgatcgcgc
    24601 gccagccggc gctgcggagc gggttcgtct gggaaggcgt cagcgagccg gtgcaggtcg
    24661 tgctggccga tgtcgacgtt ccgctgcagc tgcgcgactg gtccgggctc gacggcgaca
    24721 cccagcagga acggttgcgg gagctgctgg cgcaggaccg cgcgctcggc ttcgacctgg
    24781 cggcgccgcc gttgacgcgc ctgtacctcg tcgaccgggg ctgcgggcag tactggcttg
    24841 tttggggcct gtaccagggt ttgtgcgacg ggtggagcct gcccgtcgtg atggacgagg
    24901 tgtccgccgt ctaccagggc gaggcactcg ccccggtgcg gtcgtaccgc gagttcatcg
    24961 cctggctgga ccgacgtgat ccggccgagc ccgagcggtt ctggcgcacg tacctggacg
    25021 ggttcgaggc ccccacgcca cttccggtcg atcggctggc gagcagccac tacgcgcagg
    25081 accgccgcag aacggcgctg tccgcggatg tcacggccaa gatcgtcgac ctggcccgcc
    25141 gggagcgcgt gacgttgtcg gcggtggtgc aggccgcgtg ggccaaggtg ctgtcggcgt
    25201 cctccggcga ggacgaggtg gtgttcggcc tgaccgtgtc gggccgcccg cccgagctgg
    25261 ccggtgtcga gtcgaccgtg ggcctgttca tcaacacgtt gccggtgcgg gccgttgtcc
    25321 cctcggacgt gccgttcacg tcgtggctgc gtgagttgcg ggacaaccag gttgcgctgc
    25381 aacggttcga gtgctcgccg ctggtcgacg tgcagcgctg gtcggctgtg cccgccggcc
    25441 gcgcgctgtt cgacagcatc gtggtgctgc gcaactatcc cggcggccgg acgcgggtcg
    25501 ccgacttcga gctgtcgccg ctgctcgact cggtggagca gggcaactac ccgctcacct
    25561 tcgcggtgga cgtcgatgcc acgctgcgca tcgaggcgga gtactcgacg gcggcattcg
    25621 acgcggtcac ggtcgagcgg atcctccacc agctcaccgt cgtgctggcg gccgtggcgg
    25681 agcagcctga gctggcggtg cgggacgtgc cgttgcaacg gccggagcag gcggcggcgt
    25741 tggtggcgtg gggtgccggc ccggtgcctg ctgccgagcg gccggtgccg gacctgatcg
    25801 acgggtgggc gcggacctcg gccgaggtcg cggtgatctg cggcgaggag cggctgacgt
    25861 tcgccgagct gggtgctcgg gccgatgctt tggccgggcg gctgcgtcgc cgcggtgtga
    25921 cgaccgagtc gccggtggcg gtgttggtgc cgcgtgggat cgagctggcg gtggcgttcc
    25981 agggtgtgtt gcgcagtggt ggcgtgtatg tgccggtcaa cc
//
