LOCUS       NZ_QGHB01000004        31382 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Lentzea atacamensis strain DSM 45480 Ga0215650_104, whole genome
            shotgun sequence.
ACCESSION   NZ_QGHB01000004
VERSION     NZ_QGHB01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea atacamensis
  ORGANISM  Lentzea atacamensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 636948)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 636948)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Expected Final Version            :: No
            Genome Coverage                   :: 90.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003148865.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:35:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,333
            CDSs (total)                      :: 9,254
            Genes (coding)                    :: 9,110
            CDSs (with protein)               :: 9,110
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 6 (5S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 32 of 144
            Pseudo Genes (incomplete)         :: 121 of 144
            Pseudo Genes (internal stop)      :: 2 of 144
            Pseudo Genes (multiple problems)  :: 11 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:50:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 228426
            Orig. end                         :: 259808
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QGHB01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31382
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="2"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..31382
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31382
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:21382]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..21382
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            complement(732..1559)
                     /locus_tag="C8D88_RS18275"
                     /old_locus_tag="C8D88_104230"
     CDS             complement(732..1559)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075387.1"
                     /locus_tag="C8D88_RS18275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104230"
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="WP_109636689.1"
                     /transl_table=11
                     /translation="MPIDPDVAIGAELPEIKFSWTHSDVLLYHLALGATELRYVYERGL
                     RVLPTFGVVAPRFHETAPPAVSFPGIDIDLARVLHGTQEITVHAPIPAEGEAVLRTRIA
                     DVWDKGKAAVIVQESTAVTPDGTALYTTRSSIFARGEGGFGGERGPSGKVEVPAREPDA
                     VIETSTLPQQAHLYRLCGDRNPLHADPEFARLAGFDQPILHGLCTYGVVCKAVVDALLD
                     GPEQVSSFGAKFAGVVFPGETLTTRVWRDGSQLVLTTSAADRPVLADAVLSLA"
     gene            complement(1570..2535)
                     /locus_tag="C8D88_RS18280"
                     /old_locus_tag="C8D88_104231"
     CDS             complement(1570..2535)
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637494.1"
                     /locus_tag="C8D88_RS18280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104231"
                     /product="ferredoxin--NADP reductase"
                     /protein_id="WP_109636690.1"
                     /transl_table=11
                     /translation="MAEVHRLRVDAVIEETEDARSFVLSGADFAPRPGQFLTVRAGDVA
                     RCYSLSSAPGEPLKITVKRTPDGYGSHWMCSEVQVGTELDVLAPAGVFTPSSLDGSLLA
                     FAAGSGITPVMSIIRAVLAEAGRVFLFYANRDEGSVIFARELDELARAHPDRLVVVHWL
                     ESVQGLPHVKALRAFVRPCDEAFVCGPGPFMEAARKALHGVPVVHIEKFVSLSSDPFSE
                     AVPVADDRPDAVVEVELDGEHHRFPWPARTRLLDLLLEKGLDAPYSCREGACSACACRL
                     VEGEVKMLNNDVLDSEDIADGIVLACQSVPVTDTVKITYE"
     gene            complement(2528..2734)
                     /locus_tag="C8D88_RS18285"
                     /old_locus_tag="C8D88_104232"
     CDS             complement(2528..2734)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020644998.1"
                     /locus_tag="C8D88_RS18285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104232"
                     /product="hypothetical protein"
                     /protein_id="WP_109637072.1"
                     /transl_table=11
                     /translation="MAPVRCDCGNRVLVKKNSPQHTSVQWLSDTSSCPELCGPRSAFVP
                     TCLRLRDSIEKAVRDGTLEVADG"
     gene            complement(2764..3906)
                     /locus_tag="C8D88_RS18290"
                     /old_locus_tag="C8D88_104233"
     CDS             complement(2764..3906)
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153874.1"
                     /locus_tag="C8D88_RS18290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104233"
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_109636691.1"
                     /transl_table=11
                     /translation="MTQDAVRTIDTGAPPARFARGWHCLGLADSFRDGKPHAVEAFGTK
                     LVVFGTEDGKLNVLDGYCRHMGGDLTQGTVKGNTVACPFHDWRWAGNGKCVEIPYAKRV
                     PLRARTRSWITMEENKQLFVWNDPQGNPPPEHVTIPRIDAAFSDEWSNWTWDSVVIDNA
                     NCREIIDNVVDMAHFFYIHFAFPTYFKNVMEGHVASQYLTTRGRPDVAMGSNYTGDVEV
                     RSEASYYGPSYMIDYLWNDYKGIEIETVLINCHYPITPTSFRLQWGAIVKKLPGVSDEH
                     ADKIAAKFARGIGVGFLQDVEIWQNKTRIDNPLLCEEDGPVYQLRRWYEQFYVDVEDVT
                     DDMVRRFEFEVDTSRAVEVWEKEVAENLARREPARQEQAT"
     gene            complement(3903..5474)
                     /locus_tag="C8D88_RS18295"
                     /old_locus_tag="C8D88_104234"
     CDS             complement(3903..5474)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003092799.1"
                     /locus_tag="C8D88_RS18295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104234"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_109636692.1"
                     /sec_met_domain="DAO (E-value: 3.3e-15, bitscore: 51.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDVIVVGSGAAGMTAALCTAQHGLRTLVIEKAEHFGGSTARSGG
                     GIWVPNNHVLAGAGQADSPELAATYLEHIAGDVPAELREAFLDAGPAMLAFVCAHTPLK
                     FRWVREYADYYPEAPGGQPRGRSVEPLPFDTKLLGEEIKDLEPPYVPTPAGIVITQTDY
                     RWLTLIGRHPRGLLTAAKVFARRFLPGRRLTMGQALAAGLRAGLKAQNVEIRLNTAMTD
                     LHYENGRVAGVVVGDRLITATHVVLASGGFEHNEQLRKQHQDIGTEWTVGALANTGDGI
                     EAGVRAGAATGLMDEAWWGPSVPLPRGPYFLLAERSLPGCVLVDGTGRRFVNEAAPYID
                     VVHAMTGKTWLVFDHAYRSRYPFCGLPPRRPLPRRWQDAVLTAPSLDDLAQQADLPELT
                     ETVRRFNTLAVDGDDTDFHRGDSAYDRYYGDPRNRPNPNLAPLMTAPFYAVKIVPGDLG
                     TKGGLRTDSRARVLREDGSVIEGLYAAGNTSALVMGHTYAGAGATLGPAMTFGYLAGLD
                     ITGGTR"
     gene            5559..7064
                     /locus_tag="C8D88_RS18300"
                     /old_locus_tag="C8D88_104235"
     CDS             5559..7064
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009157037.1"
                     /locus_tag="C8D88_RS18300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104235"
                     /product="FAD-binding protein"
                     /protein_id="WP_267900062.1"
                     /sec_met_domain="DAO (E-value: 9.5e-13, bitscore: 43.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTENVFREDRVDVTADVIVIGFGAAGACAAIEAAVAGASVLVLDR
                     FAGGGATALSGGVVYAGGGTRQQVEAGVTDTPEAMFSYLKHEVRDAVSEATLRRFCEDS
                     AKMLAWLEDQGVPFDASLCPFKTSYPTDDYYLYQSGSEDAWPDPAARGHRTRAKGTSGK
                     VFFARLAEATRRAGVRIMPQTRAEELITTDGRVTGVRCRTLTGLPQTVHAMLSKAGAKP
                     WLYYPPVGRKLFALAAWLERRFSRPVTVSARQGVVISAGGFIADRDRVREISPAYRGGL
                     PLGTPGDDGSGIRLGVAAGGRTARMDKISVWRFVTPPSALQRGVLVDPEGRRFGDATRY
                     GAAIGSAIAERGGKAWLLVDDDILRVARAQVRTQAAPFQRWQVRYFLSRGMVTAPTIEE
                     VAAKAGIGTPEPFGTPPYSLINVSIKAGFGYPCPMLTLGGLVVDEETGQVRGVPGLYAA
                     GRSAVGVCSESYVSGLALADCVFSGRRAGQHVARSTDAGEARC"
     misc_feature    complement(5608..5623)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.34"
                     /tool="antismash"
     gene            7058..7828
                     /locus_tag="C8D88_RS18305"
                     /old_locus_tag="C8D88_104236"
     CDS             7058..7828
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020641798.1"
                     /locus_tag="C8D88_RS18305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104236"
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="WP_109636693.1"
                     /transl_table=11
                     /translation="MLTIQSREAAAELLRVAERDRVPIKPLVELYPEIDVVDAYEIQLL
                     NVRHRNRDVIGHKVGLSSLAMQQMMGVDEPDYGHLLDDMQLTGTADASAYLYPRVEVEI
                     AFLLSQDLPGEGCTVEDVLRATEFVAPAIELIDSRIIDWKIGLQDTIADNASSAGFILG
                     SERVRPSELDIGAVAATLRRNGEVVAEGRGDAVLGDPAIAVAWLAEKVASFGVRLLAGD
                     IVLPGSCTRAIDARPGDEFHAEFAGLGSVDLKFD"
     gene            complement(7862..9019)
                     /locus_tag="C8D88_RS18310"
     CDS             complement(7862..9019)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943560.1"
                     /locus_tag="C8D88_RS18310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_233439516.1"
                     /transl_table=11
                     /translation="MFNRTFGCVRLVWNKTLSERSDRYRDSGARTSCKQTSATLTVWKR
                     TEELSFLSEVSPVPLQQTLRHQHAAFQNFFARRARYPKVKTRNGRQTAHCTRSAFGMRH
                     GMLTLARTGLPLRFVWSFADVDVTTLDPTTVVITREPDGRWYVTFAVDAEEPAPTEPVG
                     HAIGVDLGLTDLLVTSDGLRIANPRQFARRARNLARYQRRTARCQRGSNNRRKAKTRGA
                     QVHRKIRNARRDFLHRTTTNLVRSADLIAVEDLNVAGMRRNHHVAHAISDVSWGEFKRQ
                     LACKCARAGRTLVVIDRWYPSGKTCSACGHRLTELALPARHWPCPSCRTLHDRDLNAAK
                     NILAAGRVVARSTSGDASGADVSRQGSSLPRSAMNQESCAVRRSP"
     gene            9148..10047
                     /locus_tag="C8D88_RS18315"
                     /old_locus_tag="C8D88_104238"
     CDS             9148..10047
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0008774 - acetaldehyde dehydrogenase
                     (acetylating) activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020495034.1"
                     /locus_tag="C8D88_RS18315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104238"
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="WP_109637074.1"
                     /transl_table=11
                     /translation="MVSVKAAIIGSGNIGTDLLYKLLRSPVLEPRWMVGIDPASEGLRR
                     AASLGLEVSVDGAEWLLRQDELPDVVFEATSAAVHRANAPRYAEAGIRAIDLTPAAVGP
                     YVVPPVNLGEHQDAPNINLITCGGQATIPMVHAVSRVVPVSYAEIVASVASVSAGPGTR
                     ANIDEFTRTTSKGIEAIGGAERGKAIIVLNPADPPMIMRDTIFCAIPEDADPDAITDSI
                     ARMETDIRSYVPGFRLLSEPQFDAGRVSIFVEIEGAGDFLPAYAGNLDIMTAAATKVGE
                     EIANAAASDSAADRHVTA"
     misc_feature    9159..9168
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    9931..9933
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..11023
                     /gene="dmpG"
                     /locus_tag="C8D88_RS18320"
                     /old_locus_tag="C8D88_104239"
     CDS             10001..11023
                     /EC_number="4.1.3.39"
                     /GO_function="GO:0008701 - 4-hydroxy-2-oxovalerate aldolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dmpG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020486785.1"
                     /locus_tag="C8D88_RS18320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104239"
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="WP_109636695.1"
                     /sec_met_domain="HMGL-like (E-value: 3.7e-54, bitscore:
                     179.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQRPILRLTDTSLRDGSHHKRHQFTVEDVRSIVAALDGAGVPVI
                     EVTHGDGLGGSSFNYGFSLTPEQELIKVAAETAQRARIAVLMLPGVGVKDDILVSQDNG
                     ASIVRIATHCTEADVSVQHFQLARERGLETVGFLMMAHSQPPEALARQARIMADAGCQC
                     VYVVDSAGALVLEQVSDRVAALVAELGDDAQVGFHGHENLGLSVANSVAAVRAGAKQID
                     GSVRGFGAGAGNTPLEAFVGVCDKLGFETGVDFFKIVDAAEDVVRPVMPEECLLDRMAL
                     MMGYAGVYSSFLKHAYTQAKRYGVSGAQILVRAGERKLVGGQEDQLIDIALELSREKVR
                     "
     gene            11020..12186
                     /gene="hsaA"
                     /locus_tag="C8D88_RS18325"
                     /old_locus_tag="C8D88_104240"
     CDS             11020..12186
                     /EC_number="1.14.14.12"
                     /GO_function="GO:0036383 -
                     3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione
                     monooxygenase activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="hsaA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645002.1"
                     /locus_tag="C8D88_RS18325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104240"
                     /product="3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,
                     17-dione monooxygenase oxygenase subunit"
                     /protein_id="WP_109636696.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.8e-06, bitscore:
                     24.0, seeds: 790, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEEILGKVRDLLPALRERAQEAEELRKVPPESVKALQETGFFRM
                     LQPVRYGGFESHPLDFYTAVKLIGSACGSTGWVASVLGVHPWHVGLFDVRAQDEVFGED
                     RDTRISSSYAPTGRATPVEGGFRFSGKWSFSSGCDHATWVLLGGLVMNDEGKPVDFRTF
                     LLPIADYTINDVWDTVGLRGTGSNDIVVSDVFVPEHRTLSMMHTARCVCPGQDVNPGPL
                     FRMPYGTIHPYAITAPMIGMAYGAYEVHVNATRERVRAAYLGEKSVEDPFAQVRIAMAS
                     NDIDTAWWQLEKDINDEWEHAVAGTKIPIELRLRARRDQVLGSARAISAIDRLFESAGG
                     KAINSGLPLPRFWRDAHAARVHAANDPERVLVMYGKGELGIQVRDGLF"
     gene            12197..13006
                     /gene="hsaD"
                     /gene_synonym="bphD"
                     /locus_tag="C8D88_RS18330"
                     /old_locus_tag="C8D88_104241"
     CDS             12197..13006
                     /EC_number="3.7.1.17"
                     /EC_number="3.7.1.8"
                     /GO_function="GO:0102296 -
                     4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),
                     2-diene-4-oate hydrolase activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (17-254). E-value:
                     1.6e-34. Score: 111.6. Matches aSDomain:
                     nrpspksdomains_C8D88_RS18330_Abhydrolase_1.1"
                     /codon_start=1
                     /gene="hsaD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="bphD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153877.1"
                     /locus_tag="C8D88_RS18330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104241"
                     /product="4,5:9,10-diseco-3-hydroxy-5,9,
                     17-trioxoandrosta-1(10),2-diene-4-oate hydrolase"
                     /protein_id="WP_109636697.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3e-23, bitscore:
                     78.9, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 4.7e-20, bitscore: 67.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVRLHYHEAGTDHSETLVLLHGGGPGASAMSNFGRNIPVFAKSF
                     RVLAVDMPGYGQSDKPAEHDQYFTFAARALKDLLDELGVEQAHILGNSLGGGTAVRFAL
                     DHGKRAGRLVLMGPGGLSLNVFSPDPTEGVRKLSAFAKDPTREKIEEFLRIMVFDQSLV
                     TEELIDERFEAARQPESLRAMAALGKSFAGPDFEQGMLWREAYRLRQRVLLVWGREDRV
                     NPLDGALLALKLIPRAQLHVFGGCGHWAQLEKFDEFNRLATDFLTEA"
     aSDomain        12248..12958
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS18330_Abhydrolase_1.1"
                     /evalue="1.60E-34"
                     /label="C8D88_RS18330_Abhydrolase_1.1"
                     /locus_tag="C8D88_RS18330"
                     /protein_end="254"
                     /protein_start="17"
                     /score="111.6"
                     /tool="antismash"
                     /translation="LVLLHGGGPGASAMSNFGRNIPVFAKSFRVLAVDMPGYGQSDKPA
                     EHDQYFTFAARALKDLLDELGVEQAHILGNSLGGGTAVRFALDHGKRAGRLVLMGPGGL
                     SLNVFSPDPTEGVRKLSAFAKDPTREKIEEFLRIMVFDQSLVTEELIDERFEAARQPES
                     LRAMAALGKSFAGPDFEQGMLWREAYRLRQRVLLVWGREDRVNPLDGALLALKLIPRAQ
                     LHVFGGCGHWAQLEK"
     gene            13006..13908
                     /gene="hsaC"
                     /gene_synonym="bphC"
                     /locus_tag="C8D88_RS18335"
                     /old_locus_tag="C8D88_104242"
     CDS             13006..13908
                     /EC_number="1.13.11.25"
                     /GO_function="GO:0047071 -
                     3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,
                     17-dione 4,5-dioxygenase activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="hsaC"
                     /gene_synonym="bphC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983763.1"
                     /locus_tag="C8D88_RS18335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104242"
                     /product="iron-dependent extradiol dioxygenase HsaC"
                     /protein_id="WP_109636698.1"
                     /transl_table=11
                     /translation="MGIRSLGYLRIEATDMDRWREFGLKVLGMVEGKGSTEGALYLRMD
                     DFPARLVIVPGTADRLQASGWEVATEAELDEVAKRLASAGVAVVEGSASDLAERRVNGL
                     IRFDDPSGNTLEVFHGAALEHRRVVSPYGHRFVTEEQGLGHVVLSTSDDEAALHFYRDV
                     LGFRLRDSMRLPPQFVGRPADGPPAWLRFFGCNPRHHSLAFLPMPTPSGIVHLMVEVEN
                     TDDVGLTLDRAMRRKVPMSATLGRHVNDLMLSFYMKTPGGFDVEFGCEGRQVSDEDWIA
                     RESTAVSLWGHDFSVGYQK"
     gene            13872..14441
                     /gene="hsaB"
                     /locus_tag="C8D88_RS18340"
                     /old_locus_tag="C8D88_104243"
     CDS             13872..14441
                     /EC_number="1.5.1.36"
                     /GO_function="GO:0036382 - flavin reductase (NADH) activity
                     [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="hsaB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007024416.1"
                     /locus_tag="C8D88_RS18340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104243"
                     /product="3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,
                     17-dione monooxygenase reductase subunit"
                     /protein_id="WP_267900063.1"
                     /transl_table=11
                     /translation="MGTRLQRGLPEVARYRSVLGHFCTGVTVVTGMSADGPVGFACQAF
                     AALSLDPPLVLFCPQRTSRSWAAMAASGAFCVNVLAEDQREISTVFGKAGVDKFAGVAW
                     TPSATGAPVLDGALTWVDCRVSVVHDAGDHHMVVGSVVELGPVRDAQPLLFYRGRYAVH
                     AELDTRGWSGEVLDNLLTAQRQSEWS"
     gene            complement(14427..15248)
                     /locus_tag="C8D88_RS18345"
                     /old_locus_tag="C8D88_104244"
     CDS             complement(14427..15248)
                     /EC_number="2.1.1.-"
                     /NRPS_PKS="Domain: oMT (36-133). E-value: 4.1e-11. Score:
                     33.5. Matches aSDomain: nrpspksdomains_C8D88_RS18345_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013382.5"
                     /locus_tag="C8D88_RS18345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104244"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_109636699.1"
                     /transl_table=11
                     /translation="MTPEVNSEQAALWNGPGGHGWAAARDMVDVVLQPFEDLLVAAARE
                     RPRTGVLDVGCGTGGVTRAIAAALGDVPCVGVDISGPQIAVAQESTNVRFVHADAQVHA
                     FEPQFDLIVSRFGVMFFDDPVAAFRNLGKAAKPGGELRVVVWRGKDENPFMTTAERAVA
                     PLMPDLPTFDADAPGPYGLADPDRARKVLDDSGWTGVDIRKVDLTCTMPEDVLPTYLTM
                     LGPVGRALQPMPEHERAEVLGTVLRAFEEFVQDGEVRFPTASWEIRALTPL"
     aSDomain        complement(14850..15140)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS18345_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="4.10E-11"
                     /label="C8D88_RS18345_oMT.1"
                     /locus_tag="C8D88_RS18345"
                     /protein_end="133"
                     /protein_start="36"
                     /score="33.5"
                     /tool="antismash"
                     /translation="DLLVAAARERPRTGVLDVGCGTGGVTRAIAAALGDVPCVGVDISG
                     PQIAVAQESTNVRFVHADAQVHAFEPQFDLIVSRFGVMFFDDPVAAFRNLGK"
     gene            15291..15680
                     /locus_tag="C8D88_RS18350"
                     /old_locus_tag="C8D88_104245"
     CDS             15291..15680
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005413733.1"
                     /locus_tag="C8D88_RS18350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104245"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_109636700.1"
                     /transl_table=11
                     /translation="MQELGIGEVVRRSGVPASTLRYYEERGLIGSVGRRGLTRVFDQGV
                     FQRLALISVGRAAGFTLEEIAVMFAPDGSPRLDRALLTSKADELDATIRRLTVMRDGLR
                     HAASCPAPTHMECPKFRRLLERLTG"
     gene            complement(15677..15937)
                     /locus_tag="C8D88_RS18355"
                     /old_locus_tag="C8D88_104246"
     CDS             complement(15677..15937)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D88_RS18355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D88_104246"
                     /product="hypothetical protein"
                     /protein_id="WP_109636701.1"
                     /transl_table=11
                     /translation="MLSADAARHGGRRLRRAWREPPDGAKRVYVLQVAEGVNLLGAFAG
                     LSGRLWVVLQERWPLEVVAEGESLPPCQAAAMTIAPQIWSS"
     misc_feature    complement(16094..16107)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.56"
                     /tool="antismash"
     gene            complement(16140..17168)
                     /locus_tag="C8D88_RS18360"
                     /old_locus_tag="C8D88_104247"
     CDS             complement(16140..17168)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332866.1"
                     /locus_tag="C8D88_RS18360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104247"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_109636702.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.3e-17, bitscore:
                     59.8, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.2e-23, bitscore:
                     79.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPEQLALRDTVRSLLDKHSDIRAAIEAPHGYDKDLWARLCEIGV
                     LPISEQHGGSGAGVAETLMALEELGRTLTPAPLLSSTLAAQALLVSGNDEACGRLLPRI
                     AGGTVAALAWPWATGDHVTTAPLDHPEVTTAVSDGPLHATVHHVLDGDHAEILLVTDGI
                     SLYEVDPGQPGVKREHTPAIDLTRRLATICLTDAAATRLGPWSSQVRDTALAALCAEQV
                     GAAARALELTVEYTKTRVQFGRPIGSFQALKHRMADMHVLVETARSAARAATDEVSAAV
                     AKVYCSEAFCKVAAEMIQLHGGIAITWEHDAHLYFKRAHGSAQLFGSPQDHIDRLSRPA
                     HR"
     gene            complement(17165..17980)
                     /locus_tag="C8D88_RS18365"
                     /old_locus_tag="C8D88_104248"
     CDS             complement(17165..17980)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671791.1"
                     /locus_tag="C8D88_RS18365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104248"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_109636703.1"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 9.9e-25, bitscore:
                     82.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMFTLSPEQTDFAGVLHGFLAAGRRDLAEVGVDEVTEPVDLVVVF
                     EELGHHAVPGPLIESLAVVPALVDGTATGTSSVAFPPHVPHAVEADHYFLVEGDTLREA
                     VPTAGLSSVDPARRLVELTGGAVIATGIPVTRAFDLGVLTCSAQLLGLGRAMLEMTTAH
                     TLARTQFGRPIGSFQAVKHHLANVLIGLELARPLVFGAAVTMTTRDVSAAKVAASDAAW
                     NAARTALQVHGAIGYTAEHELGRFLLQTRALRTAWGSPSLHRARVLEAL"
     gene            complement(17977..19068)
                     /locus_tag="C8D88_RS18370"
                     /old_locus_tag="C8D88_104249"
     CDS             complement(17977..19068)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020419906.1"
                     /locus_tag="C8D88_RS18370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104249"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_109636704.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.8e-20, bitscore:
                     67.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 9.7e-19, bitscore:
                     62.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 7.1e-17, bitscore:
                     57.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLSLDSSTLEFQAEVRSWLAAHVRPLSSMDTLQGFEEHRAWERL
                     LASARLSVVSWPEEFGGRDLGLLQWLIFEEEYHAAGAPGRVSQNGIFLLAPTLFSHGTD
                     EQRARILPPMARGDEVWAQAWSEPEAGSDLASLRSTAVRRDGGWLLRGQKTWSSRAAFA
                     DRAFGLFRTSAEGRHRGLTYLMFDLRADGVTVRPINQLDGEPGFAEIFLDDVFVPDHDV
                     IGEVGDGWRVAMSTAGNERGLSLRSPGRFAAAAGRLVELYRKNPDPALRDRVVDAWIGA
                     QAYRLHTFGSLANPPTGPAASVTKVFWSELDVALHETAMDLLGEVAPGWRDGWLFSLAG
                     PIYAGTNEIQRNVIAERILGLPR"
     gene            complement(19068..19898)
                     /locus_tag="C8D88_RS18375"
                     /old_locus_tag="C8D88_104250"
     CDS             complement(19068..19898)
                     /NRPS_PKS="Domain: ECH (4-231). E-value: 3.5e-31. Score:
                     100.3. Matches aSDomain:
                     nrpspksdomains_C8D88_RS18375_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332869.1"
                     /locus_tag="C8D88_RS18375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104250"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_109636705.1"
                     /transl_table=11
                     /translation="MTVSYERREAVAVVTMNRPEYRNAQNSAMTYALDEAFTRAVDDDE
                     VKVIVLAGAGDHFSAGHDIGSPGRDVDVSFERKAVLWWDHVGRSGGDLRFAREMEVYLG
                     MCRRWREIPKPMIAMVQGACVAGGLMLAWVCDLIVAAEDAFFADPVVRMGIPGVEYFAH
                     PWVLGPRAAKEVLFTGDRFSAQRAYEWGMVSRVVPRAELETSTFQLASRISAMPQFGLA
                     LAKKAVNQSEDLMGMRAGMDSVFGLHHLAHAHNAEVSPDALAGMDARSMKKASS"
     aSDomain        complement(19206..19886)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS18375_ECH.1"
                     /evalue="3.50E-31"
                     /label="C8D88_RS18375_ECH.1"
                     /locus_tag="C8D88_RS18375"
                     /protein_end="231"
                     /protein_start="4"
                     /score="100.3"
                     /tool="antismash"
                     /translation="YERREAVAVVTMNRPEYRNAQNSAMTYALDEAFTRAVDDDEVKVI
                     VLAGAGDHFSAGHDIGSPGRDVDVSFERKAVLWWDHVGRSGGDLRFAREMEVYLGMCRR
                     WREIPKPMIAMVQGACVAGGLMLAWVCDLIVAAEDAFFADPVVRMGIPGVEYFAHPWVL
                     GPRAAKEVLFTGDRFSAQRAYEWGMVSRVVPRAELETSTFQLASRISAMPQFGLALAKK
                     AVNQS"
     gene            complement(19895..21382)
                     /locus_tag="C8D88_RS18380"
                     /old_locus_tag="C8D88_104251"
     CDS             complement(19895..21382)
                     /NRPS_PKS="Domain: AMP-binding (18-399). E-value: 8.4e-94.
                     Score: 306.4. Matches aSDomain:
                     nrpspksdomains_C8D88_RS18380_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153714.1"
                     /locus_tag="C8D88_RS18380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104251"
                     /product="FadD3 family acyl-CoA ligase"
                     /protein_id="WP_109636706.1"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-99, bitscore:
                     328.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEATVASDPSRQTVSAVLDRAASLFGGAEALVDGDVRLTYTALRA
                     QVHTAARALIGMGVRPGDRVALCAPNSRHWVVAALGALHAGAALVPINTRFTAAETLDV
                     LRRSKARAFIVEGEFLGRDRLAELRGEELPEIIVRLPADWLDWATNLPSLDPDQLCDVM
                     YTSGTTGRSKGAMSAHRQSLGVAEAWASCGELSSNDRYLIVNPFFHTFGYKAGILASLL
                     RGATIVPQPVFDVVETMRLIEQERITVLPGPPTIYQTLLDHPDRGSFDLSSLRLAVTGA
                     AVVPVALVERMQTELSFSTVLTAYGLTEAVVATMCRPEDSPETVAHTCGRPMADFELRL
                     GEKDEVLLRGPNVMLGYLDDPEATAAAIDAEGWLHTGDVGRVDERGYLSITDRLKDMYI
                     CGGFNVYPAEIEQALARLPGVAESAVVGMADARLGEVGVAHVVTSPGHELTEDEVIEFC
                     RGRLANYKVPRAVEFHPALPRNAGGKVLKHLLRKENA"
     CDS_motif       complement(20150..20206)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS18380_0006"
                     /evalue="1.60E-02"
                     /label="NRPS-A_a8"
                     /locus_tag="C8D88_RS18380"
                     /protein_end="411"
                     /protein_start="392"
                     /score="8.2"
                     /tool="antismash"
                     /translation="RLKDMYICGGFNVYPAEIE"
     aSDomain        complement(20186..21328)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS18380_AMP-binding.1"
                     /evalue="8.40E-94"
                     /label="C8D88_RS18380_AMP-binding.1"
                     /locus_tag="C8D88_RS18380"
                     /protein_end="399"
                     /protein_start="18"
                     /score="306.4"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="DRAASLFGGAEALVDGDVRLTYTALRAQVHTAARALIGMGVRPGD
                     RVALCAPNSRHWVVAALGALHAGAALVPINTRFTAAETLDVLRRSKARAFIVEGEFLGR
                     DRLAELRGEELPEIIVRLPADWLDWATNLPSLDPDQLCDVMYTSGTTGRSKGAMSAHRQ
                     SLGVAEAWASCGELSSNDRYLIVNPFFHTFGYKAGILASLLRGATIVPQPVFDVVETMR
                     LIEQERITVLPGPPTIYQTLLDHPDRGSFDLSSLRLAVTGAAVVPVALVERMQTELSFS
                     TVLTAYGLTEAVVATMCRPEDSPETVAHTCGRPMADFELRLGEKDEVLLRGPNVMLGYL
                     DDPEATAAAIDAEGWLHTGDVGRVDERGYLSITDRLKDMYI"
     CDS_motif       complement(20282..20350)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS18380_0005"
                     /evalue="1.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="C8D88_RS18380"
                     /protein_end="367"
                     /protein_start="344"
                     /score="20.3"
                     /tool="antismash"
                     /translation="EVLLRGPNVMLGYLDDPEATAAA"
     CDS_motif       complement(20525..20548)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS18380_0004"
                     /evalue="8.90E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="C8D88_RS18380"
                     /protein_end="286"
                     /protein_start="278"
                     /score="0.8"
                     /tool="antismash"
                     /translation="TGAAVVPV"
     CDS_motif       complement(20696..20731)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS18380_0003"
                     /evalue="2.10E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="C8D88_RS18380"
                     /protein_end="229"
                     /protein_start="217"
                     /score="-0.3"
                     /tool="antismash"
                     /translation="LASLLRGATIVP"
     CDS_motif       complement(20846..20899)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS18380_0002"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="C8D88_RS18380"
                     /protein_end="179"
                     /protein_start="161"
                     /score="18.1"
                     /tool="antismash"
                     /translation="VMYTSGTTGRSKGAMSAH"
     CDS_motif       complement(21107..21145)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS18380_0001"
                     /evalue="1.90E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="C8D88_RS18380"
                     /protein_end="92"
                     /protein_start="79"
                     /score="8.8"
                     /tool="antismash"
                     /translation="LGALHAGAALVPI"
     misc_feature    complement(21339..21350)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.03"
                     /tool="antismash"
     gene            21425..22504
                     /locus_tag="C8D88_RS18385"
                     /old_locus_tag="C8D88_104252"
     CDS             21425..22504
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020495485.1"
                     /locus_tag="C8D88_RS18385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104252"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_109636707.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.8e-14, bitscore:
                     49.8, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.4e-27, bitscore:
                     89.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.3e-22, bitscore:
                     76.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESFRREVREWLSANLVGEFAELRGLGGPGREHEAFEGRLRWHRH
                     LAAHGWTCLGWPGERSVEEQVVFHEEYAEADAPAKVDIVGEGLLGPTLIAFGTPEQKER
                     FLPKIRSLDELWCQGYSEPGAGSDLASVQTKATLEGDQWVINGQKIWTSNAHYSDWIFV
                     LCRTEPGSQRHRGLSYLLVPMHQPGIEVRPIRQLTGTSEFNEVFFDGAVTARENVVGQP
                     GQGWKIAMATLGFERGTAMLGHQVSFRRQLDAIMAKAPDHMREKLTRAWLELHVMRSHT
                     VRTLNDDPGPEASVLKLFWGGWHRRLGELAMESLGPESMIDGNEWQRMFLFSRAETIYG
                     GSDEIQREIIAHRILGLPR"
     gene            22501..23244
                     /locus_tag="C8D88_RS18390"
                     /old_locus_tag="C8D88_104253"
     CDS             22501..23244
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (43-167). E-value: 4.5e-12.
                     Score: 38.2. Matches aSDomain:
                     nrpspksdomains_C8D88_RS18390_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671796.1"
                     /locus_tag="C8D88_RS18390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104253"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_109636708.1"
                     /sec_met_domain="adh_short (E-value: 1.9e-32, bitscore:
                     108.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 3.2e-33, bitscore:
                     111.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGHDLLRDKVVVVTAAAGTGIGSATAKRCLEEGATVVISDWHER
                     RLKETHESLGTDHAIPCDVTNEQHVQTLVDETVARYGRIDVMVNNAGLGGEKSVLDMTD
                     DEWSRVLDVTLNGTFRCTRAVLRQMVAQRSGVVVNNASVVGWRAQKGQAHYAAAKAGVM
                     ALTRCSAMDVAEHGIRVNAVAPSLAAHPFLAKVTSEELLTELASREAFGRAAEPWEVAN
                     VIVFLASDYSSYLTGEVVSVSSQHP"
     aSDomain        22630..23001
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS18390_PKS_KR.1"
                     /evalue="4.50E-12"
                     /label="C8D88_RS18390_PKS_KR.1"
                     /locus_tag="C8D88_RS18390"
                     /protein_end="167"
                     /protein_start="43"
                     /score="38.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ERRLKETHESLGTDHAIPCDVTNEQHVQTLVDETVARYGRIDVMV
                     NNAGLGGEKSVLDMTDDEWSRVLDVTLNGTFRCTRAVLRQMVAQRSGVVVNNASVVGWR
                     AQKGQAHYAAAKAGVMALTR"
     gene            23259..23864
                     /locus_tag="C8D88_RS18395"
                     /old_locus_tag="C8D88_104254"
     CDS             23259..23864
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153717.1"
                     /locus_tag="C8D88_RS18395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104254"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_109636709.1"
                     /transl_table=11
                     /translation="MSGRRAELLELAARMFAERGYGQTTVRDIADAAGILSGSLYHHFD
                     SKESMVDEILRTFLDELFTRYREIVDAGLEPKQTLKALVVASFEAIDSRHAEVAIYQNE
                     SKHLMPLERFSYLDDRNVEFRKLWTVLLEDGMRAGVFRADLDVDLAYRFIRDTVWVAVR
                     WYRPGGGLSADAVADQYLAILLDGIATGRRKNSMGNKT"
     gene            23878..25008
                     /locus_tag="C8D88_RS18400"
                     /old_locus_tag="C8D88_104255"
     CDS             23878..25008
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033648.1"
                     /locus_tag="C8D88_RS18400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104255"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_109636710.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 6.6e-08, bitscore:
                     27.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEAYIIEAVRTPAGRRGGELSHVHPADLGAHVITALLNRVDVDP
                     TDVDDVIFGCVDTVGPQAGDIARTSWLAAGFPEQVPGVTVDRQCGSSQQALHFAAQAVM
                     SGTADVVVAGGVQNMSQVPIGSAMTVSPFEGCEGWQHRYGDEEVNQFRAADLIAVRWDL
                     SRREMEEYALQSHLRALTAIKEGRFDREIAPVDGVVHDECPRPDTSAEKMAALQPLRPG
                     GRTTAALSSQISDGASAVLVVSERAMRERKLTPRARVHHLSARGSDPIYMLTAPIRATR
                     YALERAGMSISDIDLFEINEAFASVPLAWAKELRVDLGKVNVNGGALALGHPIGATGTK
                     LFTTLLHELERSGGRYGLQTMCEGGGQANVTIIERL"
     gene            complement(24992..26053)
                     /locus_tag="C8D88_RS18405"
                     /old_locus_tag="C8D88_104256"
     CDS             complement(24992..26053)
                     /EC_number="1.13.12.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033635.1"
                     /locus_tag="C8D88_RS18405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104256"
                     /product="nitronate monooxygenase family protein"
                     /protein_id="WP_109636711.1"
                     /transl_table=11
                     /translation="MRTALTELVGVRHPVVQTGMGWVAGPRLVSATAEAGGLGILASAT
                     MTYAELEAAIKETRSRTSQPFGVNLRADAQDAAERVDLLIREQVKVASFALAPKPDMIA
                     KLNDAGVVVIPSVGAARHAEKVAKWGAHAVIVQGGEGGGHTGGVATTLLLPSVLDAVDI
                     PVIAAGGFFDGRGLAAALAYGAAGIAMGTRFLLTQESTVPDAVKHAYLRRDLNGTVVTT
                     RVDGLPHRVLRTDLVNHLERSGRVSSLTRAITNAARFRRHTGLTWRAMIREGLAMKHGK
                     DLTWSQVIMAANTPMLLRAGLVEGRTDAGVLASGQVAGLLQDLPTCEDLITGIVHDAEK
                     IIARMGNSLRDVR"
     gene            complement(26050..26763)
                     /locus_tag="C8D88_RS18410"
                     /old_locus_tag="C8D88_104257"
     CDS             complement(26050..26763)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033634.1"
                     /locus_tag="C8D88_RS18410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104257"
                     /product="CoA-transferase subunit beta"
                     /protein_id="WP_109636712.1"
                     /transl_table=11
                     /translation="MSDITRAEICVTACADLFAGAGETLASPMGLIPSLGAKLARLTTE
                     PDLLLSDGEAFLLTPESTVEGWLPYRKVFDVVAHGRRHVVMGANQVDRFGNQNISAIGD
                     HARPTRQLLGFRGAPGNTVNHRTSYWVPRHSPRVLVETVDVVSGVGYDHAVGPFHDIHR
                     VVTNLAVLDFNTPDHSMRLVSTHPGVSVDEVQKQTSFPLAAADVTETRLPTDEELKLLR
                     TVLDPDSKRDREVPS"
     gene            complement(26760..27557)
                     /locus_tag="C8D88_RS18415"
                     /old_locus_tag="C8D88_104258"
     CDS             complement(26760..27557)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033633.1"
                     /locus_tag="C8D88_RS18415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104258"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_109636713.1"
                     /transl_table=11
                     /translation="MRDKRMTADEAVAGIKDGMTVGIGGWGSRRKPMALVKAILRTDLK
                     DLTLVTYGGPDVGLLCAAGKVRKLVYGFVSLDTIPYDPWFKRVREAGGIDVLELDEGMF
                     QTGLRAAAHRLPFLPIRAGLGSDVLKYAPELRTVRSPYDDGEELVAMPALKLDVALVHL
                     NRADRHGNAQYLGPDPYFDDLFCLAADRRYVSCEQIVETFDGPPQTLLLNRMMVDGVVE
                     APGGAGFTSCVPDYPRDEKLQREYAEAAGDLEKWPGFYERLLA"
     gene            complement(27532..28299)
                     /locus_tag="C8D88_RS18420"
                     /old_locus_tag="C8D88_104259"
     CDS             complement(27532..28299)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (7-210). E-value: 2.8e-48. Score:
                     156.3. Matches aSDomain:
                     nrpspksdomains_C8D88_RS18420_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019809646.1"
                     /locus_tag="C8D88_RS18420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104259"
                     /product="enoyl-CoA hydratase family protein"
                     /protein_id="WP_109636714.1"
                     /transl_table=11
                     /translation="MGISSSHTENGIIEVTVDIPPVNAIPARGWFELAETITYAGRDPE
                     ARVVILRAEGRGFCAGVDIKEIQRTPGHEALIAANRGCAKAFAAVYDCEVPVIAAVNGF
                     CLGGGIGLVGNADVIVASDDATFGLPEVDRGALGAATHLARLVPQHLMRTLYYTARNIS
                     AQALHHHGSVYDVVPREQLDDAAREIAKEIAKKDPTVIRAAKEAINGIDPQRVHTSYRY
                     EQGFTFELNLTGVSDHARQAFLDGNHARQANDG"
     aSDomain        complement(27670..28278)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS18420_ECH.1"
                     /evalue="2.80E-48"
                     /label="C8D88_RS18420_ECH.1"
                     /locus_tag="C8D88_RS18420"
                     /protein_end="210"
                     /protein_start="7"
                     /score="156.3"
                     /tool="antismash"
                     /translation="TENGIIEVTVDIPPVNAIPARGWFELAETITYAGRDPEARVVILR
                     AEGRGFCAGVDIKEIQRTPGHEALIAANRGCAKAFAAVYDCEVPVIAAVNGFCLGGGIG
                     LVGNADVIVASDDATFGLPEVDRGALGAATHLARLVPQHLMRTLYYTARNISAQALHHH
                     GSVYDVVPREQLDDAAREIAKEIAKKDPTVIRAAKEAING"
     misc_feature    complement(28302..28311)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            28370..29122
                     /locus_tag="C8D88_RS18425"
                     /old_locus_tag="C8D88_104260"
     CDS             28370..29122
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-157). E-value: 1.8e-09. Score:
                     29.7. Matches aSDomain:
                     nrpspksdomains_C8D88_RS18425_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332892.1"
                     /locus_tag="C8D88_RS18425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104260"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_109636715.1"
                     /sec_met_domain="adh_short (E-value: 1.9e-31, bitscore:
                     104.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.2e-35, bitscore:
                     119.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELSLDGSVVLVTGGVRGVGLGITRAFLAAGATVVTCARRPAEVP
                     GASFVQCDVRDAEQVSSLVSGIVSRFGRLDVLVNNAGGAPFALAEKASPRFHQKIVELN
                     LLAPLLVSQAAHAALQDSGGSIVMVSSVSGRRPSPGTAAYGAAKAGLDNLTASLAVEWA
                     PLVRVNALAVGMVRTEQSHLHYGSAEGIAAVERTVPLGRLASPDEIGACAVFLASPLAS
                     YVTGSTLVVHGGGEVPAFLDAAKTDGSS"
     CDS_motif       28394..28474
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS18425_0001"
                     /evalue="7.30E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="C8D88_RS18425"
                     /protein_end="35"
                     /protein_start="8"
                     /score="9.0"
                     /tool="antismash"
                     /translation="VVLVTGGVRGVGLGITRAFLAAGATVV"
     aSDomain        28394..28840
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS18425_PKS_KR.1"
                     /evalue="1.80E-09"
                     /label="C8D88_RS18425_PKS_KR.1"
                     /locus_tag="C8D88_RS18425"
                     /protein_end="157"
                     /protein_start="8"
                     /score="29.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLVTGGVRGVGLGITRAFLAAGATVVTCARRPAEVPGASFVQCD
                     VRDAEQVSSLVSGIVSRFGRLDVLVNNAGGAPFALAEKASPRFHQKIVELNLLAPLLVS
                     QAAHAALQDSGGSIVMVSSVSGRRPSPGTAAYGAAKAGLDNLTAS"
     CDS_motif       28748..28834
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS18425_0002"
                     /evalue="2.00E-05"
                     /label="PKSI-KR_m4"
                     /locus_tag="C8D88_RS18425"
                     /protein_end="155"
                     /protein_start="126"
                     /score="17.1"
                     /tool="antismash"
                     /translation="VMVSSVSGRRPSPGTAAYGAAKAGLDNLT"
     gene            29119..29982
                     /locus_tag="C8D88_RS18430"
                     /old_locus_tag="C8D88_104261"
     CDS             29119..29982
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-170). E-value: 1.3e-12. Score:
                     39.9. Matches aSDomain:
                     nrpspksdomains_C8D88_RS18430_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983390.1"
                     /locus_tag="C8D88_RS18430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104261"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_109636716.1"
                     /transl_table=11
                     /translation="MMLCEDRVVIVTGAGRGIGRAHALAFAAAGARVVVNDLSVGPASE
                     VASLIGPRAVVNTDDVGTWAGAARVVEAAVSAFGGLDVLVNNAGIVRDRMVVSCGEDEW
                     DEVVRVHLKGHFAPLHHAAAYWRGVHKAGGAVSGRVINTSSGAGLFGSVGQANYSSAKA
                     GIAAMTLVAAAELARYGVTVNAIAPAARTRMTEATFAESMAAPDGGFDAMAPENVSPLV
                     VWLGSAEAADVTGRMFEVDGGRICVVHGWQRGPEIDKGARWAPDELGGVVRQLVAEDHP
                     VPVYGA"
     aSDomain        29140..29628
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS18430_PKS_KR.1"
                     /evalue="1.30E-12"
                     /label="C8D88_RS18430_PKS_KR.1"
                     /locus_tag="C8D88_RS18430"
                     /protein_end="170"
                     /protein_start="7"
                     /score="39.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVIVTGAGRGIGRAHALAFAAAGARVVVNDLSVGPASEVASLIGP
                     RAVVNTDDVGTWAGAARVVEAAVSAFGGLDVLVNNAGIVRDRMVVSCGEDEWDEVVRVH
                     LKGHFAPLHHAAAYWRGVHKAGGAVSGRVINTSSGAGLFGSVGQANYSSAKAGIAAMTL
                     "
     CDS_motif       29143..29223
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS18430_0001"
                     /evalue="1.70E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="C8D88_RS18430"
                     /protein_end="35"
                     /protein_start="8"
                     /score="11.1"
                     /tool="antismash"
                     /translation="VIVTGAGRGIGRAHALAFAAAGARVVV"
     CDS_motif       29545..29601
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8D88_RS18430_0002"
                     /evalue="3.70E-06"
                     /label="PKSI-KR_m4"
                     /locus_tag="C8D88_RS18430"
                     /protein_end="161"
                     /protein_start="142"
                     /score="19.5"
                     /tool="antismash"
                     /translation="TSSGAGLFGSVGQANYSSA"
     gene            complement(29955..30905)
                     /locus_tag="C8D88_RS18435"
                     /old_locus_tag="C8D88_104262"
     CDS             complement(29955..30905)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015531.5"
                     /locus_tag="C8D88_RS18435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_104262"
                     /product="S41 family peptidase"
                     /protein_id="WP_146231551.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 3.9e-28, bitscore:
                     93.5, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVSGQRPTVGAEDRRRVLERAADLMESRYVSIEVGRSLAQQLRH
                     DAAADRWQALSDPGEFAAALTEHLREGSDDGHLAVSYSAAALPAVEITAGDAYSEQEAE
                     RYYGRRVNHGFEKFELLPDNIGYLSLRVFAPPAMAGDVAAAAMTLLAQADAMIIDLRRN
                     GGGHSDMVALLAAYLFDRSEPLSSTYYRPEDRLTTSNTPAWVPGRRYGATKPVYVLISP
                     KTFSAAEHFAYDLQALGRAVVVGEPSGGGAHPFEYRRLHPHFVLCLAESRSVNPITNGN
                     WQGVGVVPDIAVPADRALDAALELIRAQAPYTGTG"
     misc_feature    31186..31200
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
ORIGIN
        1 ggatcatggc cgatctggag tggggcctgt tctccggggt gaacgccggg tacaacagga
       61 acccgaccat caaccaccgc ttcgtgacgg cgatcgtcaa gggcgagccg aaccactggg
      121 cgatccgcgg cggcaacgcg cagtcgggcg ggctgtcgac catgttcgac ggcccgcgtc
      181 ccaacggcta ccacccgatg aagaagcagg gcgcgatcct cctcggcatc ggcggcgaca
      241 acagcgtcac cggcgccggc acgttcttcg agggcgtgct cacctccggc tatccgtcga
      301 acgccaccga ggacgccgtg caggccaaca tcaccgcggc cggttacgca cccttcacgc
      361 agccgggcag gcagatcgtc ggcagccagc ccggccggtg cgtcgacgtg ccggccggca
      421 ccaacggcac ctgggcgcag ctggcggact gccagagcgc cgatcggcag cgctggacca
      481 ccacggcgga caagaggctg cagatctacg gcaacaggtg cctcgacgcc aacggccagg
      541 gcaccaccaa cggcatccag gtgatcatct gggactgcca cggtggcgcc aaccagcagt
      601 ggaacgtcaa ctcgaacggc accatctccg gcgtgcagtc aggtctgtgc ctggacgcct
      661 acggcgcagg cacgaccaac ggcacgaggc tgattctctg gtcgtgtcac gcggcaccaa
      721 ccagcagtgg gctatgcgag gctgagcacg gcatcagcga gcacgggacg gtcggcggcg
      781 gaagtcgtca gcaccagctg tgaaccgtcc cgccacaccc gagtcgtcag cgtctcgccg
      841 gggaacacca cgccggcgaa cttcgctccg aacgacgaca cctgctccgg cccgtccagc
      901 agcgcgtcga ccactgcctt gcacaccacg ccgtacgtgc agagcccgtg caggatcggc
      961 tggtcgaacc cggccagccg ggcgaactcc ggatcggcgt gcagcgggtt ccggtcgcca
     1021 caaagccgat acagatgggc ctgctgcggc aaggtcgaag tctcgatcac cgcatcgggc
     1081 tcgcgtgcag gcacctcgac cttgccagaa ggcccgcgtt cgccgccgaa cccgccctcg
     1141 ccgcgcgcga agatgctgga ccgcgtcgtg tacagggcgg tcccgtcggg agtgacggcc
     1201 gtcgactcct gcacgatgac ggcggctttc cccttgtccc acacgtccgc gatccgcgtc
     1261 cgcagcacgg cctcaccttc ggcggggatg ggcgcgtgca cggtgatctc ctgcgtcccg
     1321 tgcagcaccc gggcgaggtc gatgtcgatg ccggggaagg acacggcggg cggcgcggtc
     1381 tcgtgaaaac ggggcgcgac aacgccgaac gtcggcagca cccgcagtcc ccgctcgtag
     1441 acgtagcgga gttcggtcgc cccgagtgcc aggtggtaga gcagcacgtc cgagtgcgtc
     1501 caggagaact tgatctcggg aagttccgcc ccgatcgcaa cgtccgggtc gatcggcatc
     1561 aggcgcccct cactcgtagg tgatcttcac ggtgtcggtg accggaaccg actggcacgc
     1621 cagcacgatg ccgtcggcga tgtcctcgga gtcgagcacg tcgttgttga gcatcttgac
     1681 ctcgccctcg acgagccggc acgcgcacgc gctgcacgct ccctcgcggc acgagtacgg
     1741 cgcgtcgagc cccttctcca gcaacaggtc gagcagcctc gtccgcgccg gccacggaaa
     1801 ccggtggtgc tcaccgtcca gctcgacctc gaccacggcg tccggtcgat cgtccgccac
     1861 cggtaccgcc tcggagaacg gatcactgga caacgacacg aacttctcga tgtgcacgac
     1921 cggaacgccg tgcagtgcct tgcgcgctgc ctccatgaac ggccccggcc cgcacacgaa
     1981 cgcctcgtca caaggccgga cgaacgcacg caacgctttc acgtgcggca agccctgcac
     2041 cgattccagc cagtgcacga ccaccagccg atccggatgg gcccgcgcca gctcgtcgag
     2101 ctcgcgagcg aagatcaccg agccctcgtc ccggttggcg tagaacagga acacgcggcc
     2161 ggcttcggcc agcaccgccc tgatgatgga catcaccggc gtgatcccgc tgccggccgc
     2221 gaacgcgagc aacgacccgt ccagcgagga aggcgtgaac accccggcgg gcgccagcac
     2281 gtccagctcg gtgccgacct gaacctcgga gcacatccag tgcgagccgt acccgtccgg
     2341 cgtccgcttg accgtgatct tcaacggctc acccggcgcg ctggacaggg agtagcagcg
     2401 cgccacgtcg cccgcccgca cggtcaggaa ctggccgggc cgtggcgcga agtcggcgcc
     2461 ggacaacacg aacgagcggg cgtcctcggt ctcctcgatc acggcgtcga cccgcaaccg
     2521 gtgcacctca gccatcggcg acctccagcg tcccgtcgcg cacggccttc tcgatgctgt
     2581 cgcgcagccg caggcacgtc ggcacgaacg cggaccgcgg cccgcacagc tcggggcagg
     2641 agctcgtgtc gctgagccac tgcacgctcg tgtgctgcgg gctgttcttc ttgaccagca
     2701 cccggtttcc gcagtcgcac cgcaccggcg ccatcccgcc gacgaggaac tcgtcgcgct
     2761 cgttcacgtc gcctgctcct ggcgtgccgg ttccctccgg gcgaggttct cggcgacctc
     2821 cttctcccac acctcgaccg cccggctcgt gtccacctcg aactcgaagc gccgcaccat
     2881 gtcgtcggtg acgtcctcca cgtcgacgta gaactgctcg taccagcgcc gcagctggta
     2941 gacaggcccg tcctcctcgc acagcaacgg gttgtcgatg cgggtcttgt tctgccagat
     3001 ctccacgtcc tgcaggaacc cgacaccgat gccgcgcgcg aacttcgccg cgatcttgtc
     3061 cgcgtgctcg tcggacacac cgggcagctt cttcacgatc gcgccccact gcaaccggaa
     3121 cgacgtcggc gtgatcgggt agtggcagtt gatcagcacc gtctcgatct cgatgccctt
     3181 gtagtcgttc cacaggtagt cgatcatgta cgacggcccg tagtacgagg cctccgaacg
     3241 cacctccacg tcaccggtgt agttcgagcc catcgcgacg tccggccgtc cgcgcgtggt
     3301 caggtactgc gaggcgacat ggccttccat cacgttcttg aagtacgtcg ggaacgcgaa
     3361 gtggatgtag aagaagtggg ccatgtcgac gacgttgtcg atgatctcgc ggcagttcgc
     3421 gttgtcgatc accaccgagt cccacgtcca gttgctccac tcgtcgctga acgcggcgtc
     3481 gatgcgcggg atcgtcacgt gctccggcgg cgggttgccc tgcgggtcgt tccacacgaa
     3541 gagctgcttg ttctcctcca tcgtgatcca cgaccgggtg cgcgcccgca gcggaacccg
     3601 tttggcgtag gggatttcca cgcacttgcc gttgcccgcc cagcgccagt cgtggaacgg
     3661 gcaggcgacg gtgttgccct tgacggtgcc ctgggtgagg tcgcctccca tgtgccggca
     3721 gtacccgtcg agcacgttga gcttgccgtc ctccgtgccg aacaccacga gcttcgtgcc
     3781 gaacgcctcc acggcatggg gtttgccgtc gcggaagctg tcggcgaggc cgagacagtg
     3841 ccagccgcgc gcgaaccgcg ccggaggtgc gccggtgtcg atggtccgca cggcgtcctg
     3901 cgtcatcgtg ttcctccagt gatgtcgagg ccggcgagat aaccgaacgt catcgccggt
     3961 ccgagggtgg cgcccgcgcc cgcgtaggtg tggcccatca ccagcgcgct ggtgtttccc
     4021 gccgcgtaca ggccttcgat caccgaaccg tcctcgcgca gcacccgcgc gcggctgtcg
     4081 gtgcgcaggc cgcccttggt gccgaggtcg ccgggcacga tcttgaccgc gtagaacggc
     4141 gctgtcatga gcggcgccag gttcgggttc gggcggttgc gcggatcgcc gtagtaacgg
     4201 tcgtacgcgc tgtcgccgcg gtggaagtcg gtgtcgtcgc cgtccacggc cagggtgttg
     4261 aaccgccgga cggtctcggt gagctccggc agatcggcct gctgggcgag gtcgtcgagg
     4321 ctgggtgcgg tgagcacggc gtcctgccag cgccggggga gcgggcggcg gggcgggagg
     4381 ccgcagaacg ggtagcggct gcggtaggcg tggtcgaaca ccagccacgt cttgccggtc
     4441 atcgcgtgca ccacgtcgat gtagggcgcc gcctcgttga cgaacctgcg cccggtgccg
     4501 tcgaccagca cacagcctgg cagtgagcgt tcggccagca ggaagtacgg gccgcgcggc
     4561 aacggcaccg acggtcccca ccacgcctcg tccatgagcc cggtggccgc gcccgcccgg
     4621 acacccgcct cgatgccgtc gccggtgttg gccagcgcgc cgaccgtcca ctccgtaccg
     4681 atgtcctggt gctgtttgcg cagctgttcg ttgtgctcga agccgccgga cgccaggacg
     4741 acgtgcgttg ccgtgatcag cctgtcgccg acgacgactc cggcgacccg gccgttctcg
     4801 tagtgcaggt cggtcatcgc ggtgttgagc cggatctcca cgttctgcgc cttcagcccg
     4861 gcgcgcaggc ccgctgccag cgcctggccc atggtcagcc gtctgcccgg caggaacctg
     4921 cgggcgaaga ccttggcggc ggtcaggagg ccgcggggat gccgtccgat cagcgtcagc
     4981 cagcggtagt cggtctgggt gatcacgatg cccgcgggtg tcggcacgta cggcggttcg
     5041 aggtccttga tctcctcgcc gaggagcttg gtgtcgaacg gcagcggttc gaccgaccgg
     5101 ccgcgcggct gtccgccggg cgcctccggg tagtagtcgg cgtactcgcg gacccagcgg
     5161 aacttcagcg gcgtgtgcgc gcagacgaac gcgagcatgg ccggtccggc gtccaggaac
     5221 gcctcgcgca gctcggcggg cacgtccccg gcgatgtgct ccaggtaggt ggcggccagt
     5281 tccggcgagt cggcctggcc ggccccggcg agcacgtggt tgttcggcac ccagatgccg
     5341 ccgccggacc tcgcggtcga gccgccgaag tgctcggcct tctcgatgac gagggtgcgc
     5401 aggccgtgtt gagcggtgca gagggcggct gtcatgcctg ccgcgccact gccgacgacg
     5461 atcacgtcgt acatcgcacc tccccgaggc tcagactaga acaggttata gttctgaggc
     5521 ggtttggcgc tatggtgtag gagttccagg caagtccgtt gaccgagaac gtgttccggg
     5581 aggatcgcgt ggacgtcacc gctgacgtga tcgtcatcgg ctttggtgcg gccggcgcgt
     5641 gcgccgccat cgaagccgcg gtggccggtg cgtccgtgct ggttctggac cggttcgcgg
     5701 gtggtggcgc gactgcgttg tccggtggcg tcgtgtacgc gggcggtggc acgaggcagc
     5761 aggtcgaggc cggagtcacg gacacgccag aggcgatgtt ctcctacctg aagcacgagg
     5821 tccgggacgc ggtgtcggag gcgacgctgc gccggttctg cgaggacagc gccaagatgc
     5881 tggcctggct ggaggaccag ggcgtgccgt tcgacgcgag cctgtgcccg ttcaagacct
     5941 cctatccgac agacgactac tacctctacc agtccggcag cgaggacgcc tggcccgatc
     6001 cggctgcgcg tggccaccgg accagggcga aaggcacctc gggcaaggtt ttcttcgccc
     6061 ggctggccga ggcgacccgg cgggcgggcg tgcggatcat gccgcagacc cgtgccgagg
     6121 agctgatcac gaccgacggc cgtgtcacgg gtgtgcgctg ccggacgctg accggcctgc
     6181 cgcagaccgt gcacgcgatg ctgtccaagg cgggcgccaa gccgtggctc tactacccgc
     6241 ccgtcggcag gaagctgttc gcgctggccg cgtggctgga acggcgcttc agccgtcccg
     6301 tcacggtgtc cgcgcggcag ggagtggtca tctcggcggg cgggttcatc gccgaccggg
     6361 acagggtgcg cgagatctcg ccggcctacc gtggtggcct cccgctcggc acgcccggcg
     6421 acgacggcag cgggatccgg ctcggtgtcg ccgccggtgg caggaccgcg cgaatggaca
     6481 agatctcggt gtggcggttc gtcacgccgc ccagtgcgtt gcaacgcggg gtgctggtcg
     6541 acccagaagg gcgcaggttc ggtgacgcga cgcggtacgg cgcggccatc gggagcgcga
     6601 tcgccgaacg cggcggaaag gcctggctgc tggtcgacga cgacatcctg cgggtcgctc
     6661 gggcgcaggt gaggacgcag gcggcgccct tccagcggtg gcaggtccgg tacttcctga
     6721 gccgcggcat ggtcaccgcg ccgacgatcg aagaggtggc ggccaaagcg gggatcggta
     6781 cgcccgaacc gttcggtacg ccgccgtact ccctgatcaa cgtctcgatc aaggccggat
     6841 tcggttaccc gtgcccgatg ctcacgctgg gcggactcgt cgtcgacgag gaaaccggcc
     6901 aggtgcgagg agttcccggc ctgtacgcgg cgggccggtc ggcggtcggc gtgtgctcgg
     6961 agtcctacgt cagcgggctc gcgctcgccg actgcgtctt ctcgggccgc cgcgccgggc
     7021 aacacgtggc caggtcaaca gatgcagggg aggccaggtg ctgacgatcc agtccaggga
     7081 ggcggccgcc gagctgctgc gcgtggcgga acgcgaccgc gtgccgatca agccgctggt
     7141 cgagctgtac cccgagatcg acgtggtcga cgcctacgag atccagctgc tcaacgtccg
     7201 gcaccgcaac cgtgacgtca tcggccacaa ggtcggcctg tcgtcgctcg cgatgcagca
     7261 gatgatgggc gtcgacgaac ccgactacgg ccacctgctc gacgacatgc agctgaccgg
     7321 caccgcggac gcttcggcgt acctgtaccc gcgggtcgag gtcgagatcg cgttcctgct
     7381 cagccaggac ctgccgggcg agggctgcac ggtcgaggac gtgctgcggg cgacggagtt
     7441 cgtcgcgccg gccatcgagc tgatcgacag ccggatcatc gactggaaga tcggcctcca
     7501 ggacaccatc gcggacaacg cctcctctgc cgggttcatc ctcggctctg agcgcgtccg
     7561 gccgtccgaa ctggacatcg gcgcggtggc ggcgacgttg cggcgcaacg gtgaagtggt
     7621 cgccgaagga cgcggtgacg cggtgctggg cgatccggcg atcgcggtgg cgtggctcgc
     7681 ggagaaggtc gcgagcttcg gcgtccggtt gctcgccgga gacatcgtgc tgcccggttc
     7741 gtgcacgcgg gcgatcgacg cgcggccggg tgacgagttc cacgccgagt tcgccggact
     7801 tggctccgta gacctgaaat tcgattgact gtttcttatc cgccttgcgg cggatgggcc
     7861 cttacgggct gcgcctcacg gcacaggatt cctggttcat cgccgatcgc ggaagggagg
     7921 acccttgccg actgacatca gctccgctgg catcacccga tgtgcttcgg gctacgactc
     7981 gaccagccgc aaggatgttc ttcgccgcgt tgaggtcccg gtcgtgcagg gtgcggcagc
     8041 tcgggcacgg ccagtgccga gcgggcagag ccagttcagt cagccggtgc ccgcaggccg
     8101 agcacgtttt gcccgacggg taccagcggt caatgaccac cagtgtgcgg ccagcgcgcg
     8161 cgcatttgca tgccagttgc cgcttgaact ccccccaact gacgtcggag atggcgtgtg
     8221 cgacgtgatg gttgcgtctc atacccgcga cgttcaggtc ttcgacagcg atgaggtcag
     8281 ccgaacgcac caggttcgtg gtcgtgcggt gcaggaagtc tcgccgtgcg ttgcgaatct
     8341 tccggtgaac ctgggcgcct cttgtctttg ctttgcggcg gttgttgctt ccgcgttggc
     8401 agcgagccgt tcggcgttga tagcgggcga ggttgcgtgc tctgcgggca aactgtcgcg
     8461 gattggcgat ccgcaggccg tcgctggtca ccaggagatc cgtcaagccg aggtcaacac
     8521 ctatcgcgtg gcctactggc tcagtgggtg cgggctcctc ggcatcaacg gcgaaggtga
     8581 cgtaccagcg tccgtctggt tcacgggtga tgaccacggt cgtcgggtcg agcgtggtca
     8641 cgtccacatc ggcgaaagac cagacgaaac gcagcggaag gcccgtcctg gcgagcgtca
     8701 gcatgccgtg ccgcattccg aatgcagagc gcgtgcagtg cgcggtttgg cggccgttgc
     8761 gggtcttgac cttcgggtag cgcgcacgcc gagcgaagaa gttctggaac gccgcgtgct
     8821 ggtggcgcag tgtctgttgc aacggcaccg gggaaacttc cgacaagaac gagagttcct
     8881 cggtgcgctt ccacacggtg agagtggcgg aggtctgctt gcacgaggtg cgcgcaccac
     8941 tgtcgcggta acggtcactc cgctcgctca gggtcttgtt ccacaccagg cgtacacaac
     9001 cgaaagtgcg gttgaacacc gcagctcgtt cgggggtcgg gtaagcccgc acctgtacgc
     9061 cgtcctcacg atacgcaatt taccgggagc catgatgagc acgacgcccc accatcgaat
     9121 tgtgcgcagc gcctgcggcg gaggctggtg gtctctgtga aggcggccat catcgggtcc
     9181 ggcaacatcg gcaccgacct gctctacaag ctcctgcgct cgccggtgct ggaaccgcgc
     9241 tggatggtgg gcatcgaccc ggccagcgag ggtctgcgcc gggcggcgtc gctgggcctg
     9301 gaggtgtcgg tcgacggcgc ggagtggttg ctgcgtcagg acgagctgcc ggacgtcgtc
     9361 ttcgaggcga cgtccgcggc ggtgcaccgg gccaacgcgc cgcgctacgc ggaggcgggc
     9421 atccgggcga tcgacctgac accggcggcg gtcgggccgt acgtcgtgcc cccggtgaac
     9481 ctcggcgagc accaggacgc gcccaacatc aacctgatca cgtgcggtgg ccaggccacg
     9541 attccaatgg tgcacgcggt gtcgcgcgtc gtcccggtgt cgtacgcgga gatcgtcgcg
     9601 agcgtggcgt cggtgtcggc gggaccgggg acgcgggcca acatcgacga gttcacccgc
     9661 acgaccagca agggcatcga ggcgatcggg ggagcggagc gcggcaaggc gatcatcgtg
     9721 ctcaacccgg cggatcctcc gatgatcatg cgcgacacga tcttctgcgc gatccccgag
     9781 gacgccgatc cggacgcgat cacggactcg atcgcgcgga tggagaccga catccgctcg
     9841 tacgtgccgg ggttccggtt gctgagcgag ccgcagttcg acgccggccg tgtgtcgatc
     9901 ttcgtcgaga tcgagggcgc gggcgacttc ttacctgcct acgccgggaa cctcgacatc
     9961 atgacggccg ccgcgacgaa ggtgggggag gagatcgcga atgcagcagc gtccgattct
    10021 gcggctgacc gacacgtcac tgcgtgacgg ctcgcaccac aagcggcacc agttcacggt
    10081 cgaggacgtc cggtcgatcg tggcggcact cgacggcgcc ggggtgccgg tcatcgaggt
    10141 gacgcacggc gacgggctcg gcgggtcgtc gttcaactac ggcttcagcc tcacgccgga
    10201 gcaggagctg atcaaggtcg ccgccgagac tgcccagcgg gccaggatcg cggtgctgat
    10261 gctgcccggt gtcggtgtga aggacgacat cctggtgtcg caggacaacg gggcgtcgat
    10321 cgtccggatc gccacgcact gcaccgaggc ggacgtctcg gtgcagcact tccagctcgc
    10381 gcgcgagcgc ggactggaga ccgtcgggtt cctgatgatg gcgcactcgc agccaccgga
    10441 ggcgctggct cgtcaagccc gcatcatggc cgacgcgggc tgccagtgcg tgtacgtcgt
    10501 cgactcggcc ggcgccctgg tgctggaaca ggtttccgac cgggtggccg cactggtggc
    10561 cgagctcggc gatgacgccc aggtcgggtt ccacgggcac gagaacctcg ggctgagcgt
    10621 cgcgaactcg gtcgcggcgg tgagagccgg ggcgaagcag atcgacggca gcgtgcgcgg
    10681 attcggtgcg ggcgcgggaa acacgccgct ggaggcgttc gtcggtgtgt gcgacaagct
    10741 cgggttcgag accggcgtcg acttcttcaa gatcgtggac gcggccgagg acgtcgtccg
    10801 gcccgtgatg ccggaggagt gcttgctcga ccggatggcg ctgatgatgg gttacgcggg
    10861 cgtctactcc agcttcctca aacacgctta cacacaggcg aaacgctacg gcgtgtccgg
    10921 cgcgcagatc ctcgtgcgcg cgggcgagcg caagctcgtg ggcgggcagg aggaccagct
    10981 gatcgacatc gcactggagc tgagcaggga gaaagtccga tgagcgagga aatcctcggc
    11041 aaggtgcggg atctgctgcc tgctctgcgg gaacgcgcgc aggaggcgga ggagctgcgc
    11101 aaggtgccgc cggagtcggt gaaggcgttg caggagaccg ggttcttccg gatgctgcaa
    11161 cccgtgcggt acggcggctt cgagtcgcat ccgctcgact tctacacggc ggtgaagctg
    11221 atcggcagcg cgtgcgggtc gacgggctgg gtcgcgtccg tgctgggcgt gcacccgtgg
    11281 cacgtcgggt tgttcgacgt ccgggcgcag gacgaggtgt tcggcgagga ccgggacacg
    11341 cggatctcgt cctcgtacgc gccgaccggc cgcgcgaccc ccgtcgaggg cgggttccgg
    11401 ttcagcggca agtggagctt ctcgtccggc tgcgaccacg cgacgtgggt gctgctcggc
    11461 ggcctggtga tgaacgacga gggcaagccc gtcgacttcc gcacgttcct gctgccgatc
    11521 gccgactaca cgatcaacga cgtgtgggac acggtcggtc tgcgcggcac cggcagcaac
    11581 gacatcgtgg tctccgacgt gttcgtgccg gagcaccgga cgctgagcat gatgcacacc
    11641 gcgcgctgcg tctgccccgg ccaggacgtc aatcccggcc cgctcttccg gatgccgtac
    11701 gggacgatcc acccgtacgc gatcaccgcg ccgatgatcg gcatggcgta cggcgcgtac
    11761 gaggtgcacg tcaacgccac ccgtgagcgg gtccgggccg cctacctggg tgagaagtcc
    11821 gtcgaggacc cgttcgccca ggtgcggatc gcgatggcgt ccaacgacat cgacacggcg
    11881 tggtggcagc tcgagaagga catcaacgac gagtgggagc acgccgtcgc cggcacgaag
    11941 atcccgatcg agctgcggct gagggcgcgg cgcgaccagg tgctcggcag tgcgcgggcg
    12001 atctccgcga tcgaccggct cttcgagagc gcgggcggca aggccatcaa cagcggcctg
    12061 ccgctgcccc ggttctggcg cgacgcgcac gccgcacgcg tgcacgcggc caacgacccg
    12121 gagcgcgtgc tcgtcatgta cggcaagggc gagctcggca tccaggtccg cgacgggctg
    12181 ttctgagggg gcgttgatga acgtgcggct gcactaccac gaggcgggca ccgaccactc
    12241 cgagacgctg gtcctgctgc acggcggcgg gcccggcgcg tcggcgatga gcaacttcgg
    12301 ccgcaacatc ccggtgttcg cgaagtcgtt ccgcgtgctg gccgtggaca tgcccggcta
    12361 cggccagtcc gacaagcccg cagagcacga ccagtacttc accttcgcgg cacgggcgct
    12421 gaaggacctg ctcgacgagc tgggtgtcga gcaggcgcac atcctgggca actcgctcgg
    12481 cggtggcacc gcggtccggt tcgctctcga ccacggcaag cgtgccggac ggctcgtgct
    12541 gatggggccg ggaggcttgt ccctcaacgt cttctctccg gacccgaccg agggtgtgcg
    12601 gaaactcagc gcgttcgcga aggacccgac acgggagaag atcgaggagt tcctgcgcat
    12661 catggtgttc gaccagtcgc tggtcaccga ggagctgatc gacgaacggt tcgaggcggc
    12721 gcggcagccg gagtcgttgc gcgccatggc cgctctcggc aagtcgttcg ccgggccgga
    12781 cttcgagcag gggatgctct ggcgggaggc atatcggttg cgccagcggg tgttgctggt
    12841 ctggggacgc gaagaccggg tcaatccgct cgacggtgcc ttgctggcgc tgaagctgat
    12901 cccgcgggcg caactgcacg tgttcggcgg ctgcggccac tgggcacagc tcgaaaagtt
    12961 cgacgagttc aaccggctgg cgaccgactt cttgacggag gcgtgatggg gatccgatcg
    13021 ctgggttatc tccggatcga ggccaccgac atggaccggt ggcgcgagtt cggactgaag
    13081 gtcctcggca tggtcgaggg caagggctcg acggaaggcg ctctttatct gcggatggac
    13141 gacttcccgg cgcggctggt gatcgtcccc ggaaccgcgg accgcttgca ggcctctggc
    13201 tgggaggtcg cgaccgaggc cgaactggac gaggtggcga agcggctggc ttccgccggt
    13261 gtcgcggtgg tggagggttc ggcttcggat ttggccgagc gccgggtcaa cgggctgatt
    13321 cgcttcgacg acccctccgg caacaccctg gaggtgttcc acggcgccgc tctggagcac
    13381 cggcgggtgg tgtcgccgta cgggcaccgg ttcgtgaccg aggagcaggg tctcgggcac
    13441 gtcgtgctgt ccacttcgga cgacgaggcg gcgttgcact tctaccggga cgtgctgggc
    13501 ttccggctgc gcgactcgat gcggttgcct ccgcagttcg tcggccgtcc ggcggacggg
    13561 ccaccggcgt ggctgcggtt cttcggctgc aacccgcgcc accacagcct ggcgttcctg
    13621 ccgatgccga cgccgagcgg gatcgtgcac ctgatggtcg aggtcgagaa caccgacgac
    13681 gtcggcctga ccctggaccg cgcgatgcgg cgcaaggtgc cgatgtcggc aacgctcggc
    13741 cggcacgtca acgacctgat gctgtcgttc tacatgaaga cacccggcgg gttcgacgtc
    13801 gagttcggct gcgagggacg gcaggtgtcc gatgaggact ggatcgcacg cgagagcacg
    13861 gcggtgagcc tgtggggaca cgacttcagc gtgggctacc agaagtagcc cgctaccgct
    13921 ccgtcctcgg tcacttctgc acgggagtga ccgtggtgac cggcatgtct gcggacgggc
    13981 cggtcgggtt cgcctgccag gcgttcgcgg cgttgtcgct cgacccgccc ctcgtgcttt
    14041 tctgtccaca acggacttcg cgcagctggg cggcgatggc ggcgtccggc gcgttctgcg
    14101 tgaacgtgct ggccgaggac cagcgggaga tctcgacggt gttcgggaag gccggcgtgg
    14161 acaagttcgc cggagtggcc tggacgccgt cggccaccgg tgccccggtg ctcgacggcg
    14221 ccctgacctg ggtcgactgt cgggtttcgg tggtgcacga cgccggcgac caccacatgg
    14281 tcgtcggctc ggtcgtcgag ctcggcccgg tgcgcgacgc gcagccgttg ctgttctacc
    14341 gcggccgcta cgccgtgcac gccgagctgg acacccgagg ctggtccggc gaggtcctcg
    14401 acaacctgct caccgcccag cgccagtcag agtggagtta gggccctgat ctcccacgac
    14461 gcggtgggga agcggacttc cccgtcctgc acgaactcct cgaacgcgcg gagcacggtg
    14521 ccgagcacct ccgcgcgttc gtgttcgggc atgggctgga gtgcccggcc caccggcccg
    14581 agcatcgtca ggtacgtcgg caacacgtcc tctggcatgg tgcaggtcag atcgaccttc
    14641 cggatgtcga cgccggtcca cccgctgtcg tccagcacct tccgcgcccg gtcggggtcg
    14701 gcgagcccgt acggcccggg cgcgtcggca tcgaacgtcg gcagatccgg catcagcggc
    14761 gcgacggccc gttccgcggt ggtcatgaac gggttctcgt ccttgccgcg ccagacgacg
    14821 acccgcagct cgccaccggg cttcgcggcc ttgccgaggt tgcggaacgc ggccaccggg
    14881 tcgtcgaaga acatgacccc gaaccgcgac acgatcaggt cgaactgcgg ctcgaacgcg
    14941 tgcacctgcg cgtccgcgtg cacgaaccgc acgttcgtgc tctcctgcgc gacggcgatc
    15001 tgcggcccgg aaatgtcgac gccgacgcac ggcacgtcgc cgagtgccgc cgcgatcgcc
    15061 ctggtcacgc ccccggtccc gcatccgaca tcgagcaccc cggtgcgcgg cctctcccgc
    15121 gccgccgcga cgagcaggtc ctcgaacggc tggagaacca cgtcgaccat gtcccgtgcc
    15181 gcggcccagc cgtgcccgcc gggcccgttc cacagtgcgg cctgttcgct gttgacctct
    15241 ggtgtcatgc tcctaccgtc ctacttcaag tcggcttgag gtcaagtgtc atgcaggagc
    15301 tgggtatcgg cgaggtggtg cggcgatccg gcgtgccggc gtccactctg cgctactacg
    15361 aggagcgcgg cctgatcgga tcggtcggcc ggcgcggcct cacgcgggtg ttcgaccagg
    15421 gcgtcttcca gcggctggcg ctgatctcgg tgggccgcgc ggcgggcttc accctcgagg
    15481 agatcgcggt gatgttcgcc cccgacggca gcccgcgcct ggaccgcgcg ctgctcacga
    15541 gcaaggcgga cgaactggac gcgacgatcc gccggctgac ggtcatgcgc gacgggttgc
    15601 ggcacgccgc gtcgtgcccg gcgccgacgc acatggagtg tccgaagttc cggcgcctgc
    15661 tggagcggct gaccggttag ctgctccaga tctgcggggc gatggtcatc gctgcggcct
    15721 ggcagggcgg cagcgattcg ccctcggcca cgacctccag cggccacctc tcctgcaaca
    15781 cgacccacaa ccgcccggag agcccggcga acgcgcccag caggttcaca ccttcggcga
    15841 cctgcagcac gtacacccgc ttcgccccgt cgggcggctc gcgccaagcc cggcgcaacc
    15901 ggcgcccgcc gtgccgcgcc gcatcggcgg acagcacgac atcggcctcg ctcttccctc
    15961 gtgatgccga tttccccgta cgccatgctc agcagcaacg tcgcctcggc ctgcgccggc
    16021 tcgccgccga agtggtcctc gcgcacggaa cggagggtgt cgtcgtccaa ccgctcgtgc
    16081 gcgcgttctg ggtcaaggat gcgtttgtcc acgagccagg agaccaggca gcggcctgat
    16141 caccggtgtg cgggacggga gaggcggtcg atgtgatctt gagggctgcc gaacagctgg
    16201 gcgctgccgt gcgcccgctt gaagtagagg tgtgcgtcgt gctcccaggt gatcgcgatg
    16261 ccgccgtgca gctggatcat ctcggccgcg accttgcaga acgcttcgga gcagtacacc
    16321 ttcgcgaccg ctgcggacac ctcgtcggtg gcggcccgcg cggccgacct cgcggtctcc
    16381 accaggacgt gcatgtccgc catgcggtgc ttcaacgcct ggaacgaacc gatcggccgc
    16441 ccgaactgga ccctggtctt cgtgtactcg acggtgagct ccagtgctct ggcggcggcg
    16501 ccgacctgtt ccgcgcacag tgcggccagt gccgtgtcac gtacctggga cgaccatggg
    16561 cctaggcggg tcgcggcggc gtcggtgagg cagatggtgg ccaggcggcg ggtcaggtcg
    16621 atggccggcg tgtgttcgcg cttgacgccg ggctggccgg gatcgacctc gtagagcgag
    16681 atgccgtcgg tgaccagcag gatttcggcg tggtcgccgt cgaggacgtg gtggacggtg
    16741 gcgtggagag ggccgtcgga gacagccgtg gtcacctcgg ggtggtcgag cggagccgtg
    16801 gtgacgtggt caccggtggc ccagggccag gcgagtgcgg cgacggttcc gccggcgatc
    16861 cgcggtagca gccggccaca ggcctcgtcg tttccgctga cgagcagtgc ctgtgcggcc
    16921 agcgtcgacg agagcagggg agcgggcgtg agcgtgcggc cgagttcttc cagcgccatc
    16981 agggtttccg cgaccccggc accggatccg ccgtgctgct cggagatcgg gaggacaccg
    17041 atctcgcaca gccgcgccca caggtccttg tcgtagccgt gcggggcttc gatcgcggca
    17101 cggatgtcgg agtgcttgtc gagcaggctg cggacggtgt cgcgcagtgc gagttgttcc
    17161 ggtgtcacaa cgcctccagc acgcgggctc ggtgcagcga cgggctgccc caggcggtgc
    17221 gcagggcccg ggtctgcagc aggaaccggc cgagctcgtg ctcggcggtg tagccgatcg
    17281 cgccgtgcac ctgcagggcg gtcctggcgg cgttccaggc ggcgtccgag gcggcgacct
    17341 tggccgccga gacgtcgcgg gtcgtcatcg tcacggcggc gccgaacacc agcgggcggg
    17401 ccagttccag tccgatcagg acgttggcga ggtggtgctt gacggcctgg aaggagccga
    17461 tcggcctgcc gaactgggta cgggccaggg tgtgggcggt ggtcatctcg agcatcgcgc
    17521 ggccgaggcc gaggagctgt gccgagcagg tcagaacgcc gaggtcgaag gcgcgggtga
    17581 ccgggatccc ggtggcgatc accgcgccgc cggtcagctc gacgaggcgg cgggcggggt
    17641 ccaccgagga cagtccggcg gtggggacgg cctcgcggag ggtgtcgcct tcgacgagga
    17701 agtagtggtc ggcttcgacg gcgtgcggga cgtgaggtgg gaaggcaacc gacgaggtac
    17761 ccgtcgccgt cccgtccacc agcgccggaa ccaccgccag ggactcgatc agcggccccg
    17821 gcaccgcgtg atgccccagc tcctcgaaca ccaccacgag gtcgaccggc tccgtcacct
    17881 cgtccacccc gacctcggcc aggtcccgcc tccccgccgc gaggaacccg tgcagcaccc
    17941 cggcgaagtc cgtctgctcc ggcgacagcg tgaacatcat cgtggcaacc ccaggatccg
    18001 ttcggcgatg acgttgcgct ggatctcgtt ggtgccggcg tagatgggcc ccgccagcga
    18061 gaacagccag ccgtcccgcc atcccggcgc gacctcgccc agcaggtcca tcgcggtctc
    18121 gtgcagtgcc acgtccagct cggaccagaa caccttcgtg acgctcgcgg ccggtcccgt
    18181 gggcgggttg gccagcgagc cgaacgtgtg cagccggtag gcctgggcac cgatccacgc
    18241 gtcgacgacc cggtcgcgca acgccggatc cgggttcttg cggtacagct ccacgagccg
    18301 ccccgcggcg gcggcgaacc tgccgggact gcgcaacgac aggccgcgtt cgttgcccgc
    18361 ggtgctcatc gccacgcgcc agccgtcgcc gacctcgccg atgacgtcgt ggtccggtac
    18421 gaacacgtcg tccaggaaga tctcggcgaa gcccggttcg ccgtcgagct ggttgatcgg
    18481 ccgcacggtg acgccgtcgg cgcgcaggtc gaacatcagg taggtcaggc cgcggtgacg
    18541 tccctccgcg gaggtccgga acaggccgaa cgccctgtcc gcgaacgccg cccgcgagct
    18601 ccacgtcttc tggccgcgca gcagccagcc accatcacga cgaacggcgg tgctgcgcaa
    18661 cgacgccagg tcggatccgg cctcgggttc cgaccacgcc tgcgcccaca cctcgtcgcc
    18721 gcgcgccatc ggcggcagga tccgcgcgcg ctgctcgtcg gtgccgtgag agaacaacgt
    18781 cggcgccagc aggaagatgc cgttctggga gacgcgaccg ggcgcgccgg cggcgtggta
    18841 ctcctcctcg aagatcagcc actgcagcag acccaggtcg cggccaccga actcctctgg
    18901 ccacgacacc accgacaacc gggccgaggc gagcagccgt tcccacgcgc ggtgctcttc
    18961 aaagccctgc aaggtgtcca tcgaggacag tggccggacg tgcgcggcca gccacgagcg
    19021 cacctcggct tggaactcaa gagtcgagga gtccagtgag aggtccatca gctggaggcc
    19081 ttcttcatcg aacgggcgtc catgcccgcc agcgcgtccg ggctcacctc ggcgttgtgg
    19141 gcgtgggcga ggtggtgcaa cccgaacacc gagtccatcc cggccctcat gcccatgagg
    19201 tcctcggact ggttgaccgc cttcttggcc agggccagcc cgaactgcgg catcgccgag
    19261 atccgcgaag ccagctggaa cgtcgacgtt tccagttcgg cgcgcggcac gacacgtgag
    19321 accatgcccc attcgtaggc gcgctgggcg gagaagcggt cgccggtgaa gagcacctcc
    19381 ttggcggcgc gcgggccgag cacccacggg tgggcgaagt actcgacacc gggaattccc
    19441 atacgcacca cgggatcggc gaagaaggcg tcctctgcgg ccacgatcag gtcgcacacc
    19501 caggcgagca tcaggccgcc cgccacgcac gcgccctgca ccatcgcgat catcggcttg
    19561 gggatctcgc gccaccgccg gcacatgccg aggtagacct ccatctcgcg ggcgaagcgg
    19621 agatcaccac cggaacgccc gacgtggtcc caccacagca cggccttgcg ctcgaacgac
    19681 acgtcgacgt cccggccagg cgagccgatg tcgtggcccg ccgagaagtg gtcaccggca
    19741 ccggccagga cgatcacctt gacctcgtcg tcgtcgaccg cgcgcgtgaa ggcctcgtcc
    19801 aacgcgtacg tcatcgccga gttctgcgcg ttgcggtact ccgggcggtt catggtcacg
    19861 acggcgaccg cctcccgccg ctcatacgag actgtcacgc gttctccttg cgcagtaggt
    19921 gtttgaggac cttgccgccg gcgttgcggg ggagcgcggg gtggaactcg acggcccgcg
    19981 gcaccttgta gttggccagc cggccgcggc agaactcgat cacctcgtcc tcggtcagct
    20041 cgtggccggg cgaggtgacg acgtgcgcga cgccgacctc accgagccgt gcgtcggcca
    20101 tccccaccac ggccgactcg gcgactcccg gcaaccgggc cagcgcctgc tcgatctccg
    20161 cggggtagac gttgaacccg ccgcagatgt acatgtcctt gagccggtcg gtgatcgaca
    20221 ggtagccgcg ttcgtcgacg cgtccgacat cgcccgtgtg cagccatccc tcggcgtcga
    20281 tggccgcggc ggtcgcctcc ggatcgtcca ggtacccgag catcacgttc gggccgcgca
    20341 gcaacacctc gtccttctcg cccagccgca gctcgaagtc cgccatcggc cgcccgcacg
    20401 tgtgcgcgac ggtctccggt gagtcctcgg gacggcacat cgtggccacc acggcctccg
    20461 tgagcccgta cgcggtgagc acggtcgaga acgacagctc cgtctgcatc cgctcgacca
    20521 gcgccacggg caccaccgcg gcgcctgtca ccgcgagacg caggctggac aggtcgaacg
    20581 aaccgcgatc ggggtggtcg agcaacgtct ggtagatcgt cggcggcccc ggcagcacgg
    20641 tgatgcgttc ctgttcgatc agccgcatcg tctccacgac gtcgaacacc ggctgcggca
    20701 cgatcgtcgc gccgcgcagc aaactggcga gaatcccggc cttgtagccg aaggtgtgga
    20761 agaacgggtt gacgatcagg taccggtcgt tcgacgacag ctcaccgcag gacgcccacg
    20821 cctccgcgac cccgagcgac tgccggtgcg cgctcatcgc gcccttgctg cgcccggtcg
    20881 tgcccgaggt gtacatgacg tcgcacagct ggtccggatc gagcgacggc aggttcgtgg
    20941 cccagtcgag ccagtcggcc ggtagtcgca cgatgatctc ggggagctcc tctccgcgca
    21001 gctccgcgag ccggtcgcgg ccgaggaact cgccctcgac gatgaaggcg cgcgccttgc
    21061 tccgccgcag cacgtcgagc gtctcggcag cggtgaaccg ggtgttgatc ggtaccagcg
    21121 cggcgcccgc gtgcaaggcg cccagtgccg cgaccaccca gtgccgcgag ttgggcgcgc
    21181 acaacgccac ccggtcgcct ggccgcacac ccatcccgat gagtgcgcgt gcggcggtgt
    21241 gcacctgcgc ccgcagcgcg gtgtaggtga ggcgaacgtc cccgtccacc aacgcttccg
    21301 cgccgccgaa gagcgaggca gcgcggtcga gcaccgctga aaccgtttgc ctgcttggat
    21361 cgctggccac tgtggcctcc attgggcctc caaagcaagt gcttggtagg ttagagtatg
    21421 gcccatggag tccttccggc gcgaggtgcg ggaatggttg tccgccaacc tcgtcggtga
    21481 gttcgcggag ctgcgcggcc tgggtgggcc cggccgcgag cacgaggcgt tcgagggccg
    21541 gctgcgctgg caccggcacc tggccgcgca cgggtggacg tgcctcggct ggccgggcga
    21601 gcgcagcgtg gaggagcagg tcgtcttcca cgaggagtac gcggaggccg acgcgcccgc
    21661 gaaggtcgac atcgtgggtg agggtctgct cggcccgacg ctcatcgcgt tcggcacccc
    21721 cgagcagaag gaacgctttc tgccgaagat ccgctcactc gacgagctgt ggtgccaggg
    21781 ctactccgag ccgggtgccg gctccgacct cgcgtccgtc cagacgaagg cgaccctcga
    21841 gggcgaccag tgggtgatca acggccagaa gatctggacg tcgaacgcgc actactcgga
    21901 ctggatcttc gtcctgtgcc gcaccgagcc cggatcacaa cgccaccgcg ggctctccta
    21961 cctgctcgtg ccgatgcacc agcccggcat cgaggtccgg ccgatccgcc agctgaccgg
    22021 cacgtcggag ttcaacgagg tcttcttcga cggcgcggtc acggctcgcg agaacgtggt
    22081 cgggcagccc ggccagggct ggaagatcgc gatggccacg ctgggcttcg agcgcggcac
    22141 cgcgatgctc ggccaccagg tgagcttccg ccgccagctc gacgcgatca tggcgaaggc
    22201 tcctgaccac atgcgggaga aactgaccag agcgtggctc gagctccacg tcatgcgctc
    22261 acacacggtg agaacgctca acgacgaccc tggcccggag gcgtccgtgc tgaagctgtt
    22321 ctggggcggg tggcaccgca ggctcggtga gctcgcgatg gagtcgctcg gccccgagtc
    22381 gatgatcgac ggcaacgagt ggcagcggat gttcctgttc agccgcgcgg agaccatcta
    22441 cggcgggtcc gacgagatcc agcgcgagat catcgcccac cggattctgg ggctaccgcg
    22501 atgaccggcc acgacctgct cagggacaag gtcgtcgtcg tgaccgccgc ggcgggcacg
    22561 ggtatcggct cggcgaccgc gaaacggtgc ctcgaagagg gcgcgacggt cgtgatcagc
    22621 gactggcacg agcgccgcct caaggagacg cacgagtcgc tcggcaccga tcacgcgatc
    22681 ccgtgcgatg tcacgaacga acagcacgtg cagacgctcg tagacgaaac agtcgcgcgc
    22741 tacggccgca tcgacgtgat ggtcaacaac gcgggcctcg gcggtgagaa gtccgtgctg
    22801 gacatgaccg acgacgagtg gtcgcgcgtt ctcgacgtga cgttgaacgg cacgttccgc
    22861 tgcaccaggg ccgtgttgcg ccaaatggtc gcccagcgaa gcggtgttgt cgttaacaac
    22921 gcgagcgtcg tcggctggcg tgcccagaaa ggccaagccc attacgcggc ggcaaaagca
    22981 ggtgtcatgg cgctgacgag atgcagcgcg atggacgtgg ccgagcacgg catccgggtg
    23041 aacgcggtcg ccccgagctt ggcggcgcac ccgttcctgg ccaaggtcac cagtgaggag
    23101 ttgctgaccg agctggcgtc ccgtgaggct tttgggcgcg ccgccgagcc gtgggaggtc
    23161 gcgaatgtga tcgtgttcct cgccagcgac tactcgtcgt acctgacggg cgaggtcgtc
    23221 tcggtgagca gtcagcaccc gtgaggaagg aaagatcgat gagcggcagg agggcggagc
    23281 tgctggagct cgccgcgcgg atgttcgccg aacgtggcta cgggcagacc acggtcaggg
    23341 acatcgcgga cgcggcgggc atcctgtccg gcagcctcta ccaccacttc gactcgaagg
    23401 agtcgatggt ggacgagatc ctgcggacct tcctcgacga gctgttcacc cggtaccgcg
    23461 agatcgtcga cgcgggcctc gaaccgaagc agacgctgaa agccctggtc gtggcatcgt
    23521 tcgaggcgat cgacagccgg cacgccgagg tcgcgatcta ccagaacgag tccaagcacc
    23581 tgatgccgct ggagcggttc tcctacctgg acgaccgcaa cgtggagttc cgcaagctgt
    23641 ggacggtgct gctggaggac ggcatgcgcg cgggcgtgtt ccgcgccgat ctcgacgtgg
    23701 acctcgccta ccggttcatc cgcgacacgg tgtgggtggc cgtgcgctgg taccggccgg
    23761 gcggaggcct gtccgcggac gcggtcgccg accagtacct cgcgatcctg ctcgacggca
    23821 tcgccaccgg gcgccggaag aactcgatgg ggaacaagac gtagaaggag ggccctcgtg
    23881 gccgaggcgt acatcatcga ggctgtgcgg actccggcgg gcaggcgtgg cggcgaactg
    23941 agccacgtgc atcccgccga tctcggtgcg cacgtgatca cggcactgct caaccgcgtc
    24001 gacgtcgatc ccaccgacgt ggacgacgtg atcttcgggt gcgtcgatac ggtcgggccg
    24061 caggcgggtg acatcgcgcg gacctcgtgg ctggccgcgg ggttcccgga gcaggtgccc
    24121 ggggtgaccg tcgaccggca gtgcgggtcg agccagcagg cgctgcactt cgcggcgcag
    24181 gcggtgatga gcggcacggc ggacgtcgtg gtcgcgggcg gcgtgcagaa catgtcgcag
    24241 gtgccgatcg gatcggccat gacggtcagt ccgttcgagg gctgtgaggg ctggcagcac
    24301 cggtacggcg acgaggaggt caaccagttc cgcgcggccg acctgatcgc cgtgcggtgg
    24361 gacctctccc ggcgcgagat ggaggagtac gcgctgcaga gccacctgcg agcgcttacc
    24421 gcgatcaagg agggccggtt cgaccgggag atcgcgccgg tcgacggtgt cgtgcacgac
    24481 gagtgcccgc gtccggacac cagtgccgag aagatggcgg cgctgcagcc gttgcggccg
    24541 ggtggacgga cgacggcggc cttgtcgagc cagatctccg atggcgcctc ggcggttctc
    24601 gtcgtgtcgg aacgggcgat gcgcgagcgg aagctgacgc cgcgggctcg ggtgcaccac
    24661 ctctccgccc gcggatcgga cccgatctac atgctgaccg cgccgatccg cgccacccgg
    24721 tacgccctgg agcgagcggg gatgtccatt tcggacatcg acctgttcga gatcaacgag
    24781 gcgttcgcgt cggttccact ggcctgggcc aaggagttgc gcgtcgacct ggggaaggtc
    24841 aacgtcaacg ggggagcgct ggcgctgggg cacccgatcg gcgcgaccgg cacgaagctg
    24901 ttcacgacgc tgctgcacga gctggagcgg tcgggcggcc ggtacggcct gcagacgatg
    24961 tgcgagggcg gcggtcaggc caacgtgacg atcatcgaac gtctctgaga ctgttcccca
    25021 ttctggcgat gatcttctcg gcgtcgtgca cgatgccggt gatcaggtcc tcgcacgtcg
    25081 gcaggtcctg cagcagaccg gcgacctgac cggacgcgag cacgcccgcg tcggtcctgc
    25141 cctcaacgag gccggcgcgc agcagcatcg gcgtgttcgc ggccatgatc acctgtgacc
    25201 aggtgaggtc cttgccgtgc ttcatggcca ggccttcgcg gatcatcgcg cgccaggtga
    25261 gcccggtgtg ccggcggaac ctggccgcgt tggtgatcgc tcgtgtcagg ctgctgaccc
    25321 ggccagaccg ttcgaggtgg ttgaccaggt cggtgcgcag gacccggtgc ggcaggccgt
    25381 cgacacgggt ggtgacgacc gtgccgttca gatcccgtcg caggtacgcg tgtttgaccg
    25441 cgtcggggac cgtgctctcc tgggtgagca ggaacctcgt gcccatcgcg attccggccg
    25501 caccgtacgc gagtgctgcc gcgagccccc tgccgtcgaa gaaaccgccc gccgcgatca
    25561 ccgggatgtc cacggcgtcc agcacgctcg ggaggagcag ggtcgtcgcc acgccgccgg
    25621 tgtggccgcc gccctcgccg ccctggacga tcaccgcgtg ggcaccccac ttcgcgacct
    25681 tctccgcgtg cctggccgcg ccgaccgacg ggatcacgac gacaccggcg tcgttcagct
    25741 tcgcgatcat gtcgggtttc ggtgccagcg cgaaggaagc gaccttgacc tgttcgcgga
    25801 tcagcaggtc gacccgctcc gccgcgtcct gggcgtccgc gcggaggttc acgccgaacg
    25861 gttgtgacgt gcgggaacgg gtttccttga tggcggcttc cagctctgcg taggtcatgg
    25921 tcgccgaggc caggatgccg agccctccgg cctccgcggt cgcggagacc aggcggggcc
    25981 cggcgaccca gcccatgccc gtctgcacga cgggatgacg gacgccgacg agctcggtca
    26041 gcgcggttct catgacggga cttcccggtc gcgcttgctg tccgggtcga gcacggttcg
    26101 gaggagcttc agctcttcgt cggtgggcag cctggtctcc gtgacgtctg ccgcggcgag
    26161 cgggaacgat gtctgcttct gcacctcgtc gactgacacg ccggggtggg tggacaccag
    26221 gcgcatcgag tggtcagggg tgttgaagtc gagcacggcg aggttcgtga cgacacgatg
    26281 gatgtcgtgg aacgggccca cggcgtggtc gtagccgaca ccggagacca cgtcgacggt
    26341 ctcgaccagc acgcgcgggc tgtgccgcgg cacccagtag ctggtgcggt ggttgacggt
    26401 gttgccaggc gcgccgcgga aaccgaggag ctgcctggtg ggcctggcgt ggtcgccgat
    26461 cgcggagatg ttctggttgc cgaacctgtc gacctggttc gcgcccatca cgacgtgccg
    26521 gcggccgtgc gcgacgacgt cgaagacctt ccggtacggc agccagccct ccacagtgga
    26581 ctcgggcgtg agcaggaacg cctcgccgtc gctgagcagg aggtcgggtt cggtggtgag
    26641 gcgggcgagt ttcgcgccga gggacgggat gaggcccatc gggctggcga gcgtctcacc
    26701 ggcgcccgcg aacaggtcgg cgcacgcggt gacgcagatt tcggccctgg tgatgtcgct
    26761 catgccagca acctctcgta gaagcccggc catttctcca ggtcacccgc ggcttcggcg
    26821 tactcgcgct ggagcttctc gtcgcggggg tagtcgggga cgcagctcgt gaaccccgcg
    26881 ccacccggtg cctccacgac tccgtcgacc atcatgcggt tgagcagcaa cgtctgcggc
    26941 ggcccgtcga acgtctccac gatctgctcg cacgagacgt agcgccggtc cgcggccagg
    27001 cagaacaggt cgtcgaagta cgggtcgggc ccgaggtact gggcgttgcc gtgccggtcc
    27061 gcgcggttga ggtgcaccag cgccacgtcg agcttgagcg cgggcatggc gaccagctcc
    27121 tcgccgtcgt cgtagggcga tcggacggtc ctgagctcgg gggcgtactt gagcacgtcc
    27181 gagccgaggc ctgccctgat cggcaggaac ggcaaccggt gcgcggcggc cctgagcccc
    27241 gtctggaaca tgccctcgtc cagctccagc acgtcgatcc cgccggcttc gcggacccgc
    27301 ttgaaccacg ggtcgtacgg gatggtgtcg agcgagacga acccgtagac cagcttgcgg
    27361 accttgcccg ccgcgcacag caggccgacg tccggtccgc cgtacgtgac gagggtgagg
    27421 tctttcaggt ctgtgcggag aatcgccttg accagggcca tcggcttgcg ccgcgagccc
    27481 cagccgccga tgccgacggt catgccgtcc ttgatcccgg ctactgcctc gtcagccgtc
    27541 attcgcttgt cgcgcatggt ttccgtccag gaaggcctgc cgggcgtggt ccgacacccc
    27601 ggtgaggttc agctcgaagg tgaagccctg ctcgtagcgg tagctggtgt gcacgcgctg
    27661 cgggtcgatg ccgttgatcg cctccttggc cgcgcggatc accgtcgggt ccttcttggc
    27721 gatctccttg gcgatctcgc gggccgcgtc gtcgagctgc tcgcgcggta cgacgtcgta
    27781 gacgctgccg tggtggtgca acgcctgcgc gctgatgttc ctggccgtgt agtacagcgt
    27841 ccgcatgagg tgctgcggca cgagcctggc caggtgcgtc gcggcaccga gcgcgccgcg
    27901 atcgacttcg ggcaggccga acgtggcgtc gtcggacgcc acgatcacgt ccgcgttgcc
    27961 gaccagcccg atgccgccgc cgaggcagaa cccgttcacc gcggcgatga ccggcacctc
    28021 gcagtcgtag acagcagcga aagccttggc gcagccccgg ttcgcggcga tcagcgcttc
    28081 gtgaccgggc gtgcgctgga tctccttgat gtcgacgccc gcgcagaacc cgcggccctc
    28141 ggccctgagg atcaccaccc gtgcttcggg atcccggccc gcgtaggtga tcgtctcggc
    28201 cagctcgaac cagccgcgcg cggggatggc gttgaccgga ggtatgtcga ctgtcacctc
    28261 gatgatgccg ttttcggtgt ggctgctgga gattcccatc gcgccgcctt ccgaaccaag
    28321 cgattgcttg gtaatttagc agcgccagag cgaccggggt aggtgcggag tggaactctc
    28381 cctggacgga agcgtcgtcc tcgtgacggg cggcgtgcgg ggtgtcggcc ttgggatcac
    28441 ccgtgcgttt ctcgccgcgg gcgcgacggt cgtgacctgt gcccggcgtc ccgccgaggt
    28501 gccgggtgcg tcgttcgtgc agtgcgacgt ccgggacgcc gagcaggtgt cgtcgctcgt
    28561 gtccgggatc gtctcgcggt tcgggcggct ggacgtgctg gtgaacaacg ccggtggggc
    28621 gccgttcgcg ttggcggaga aggcttcgcc gcggttccac cagaagatcg tcgagctgaa
    28681 cctgctggcg ccgctgctgg tgtcccaggc cgctcacgca gcgctgcagg actccggcgg
    28741 ttcgatcgtg atggtcagca gcgtttccgg tcggcggcct tcgcctggga ccgccgccta
    28801 cggcgccgcc aaggccgggc tggacaacct gaccgcttcg ttggccgtcg agtgggcgcc
    28861 tctcgtgcgg gtcaacgcgc tggcagtcgg aatggtgcgg accgagcagt ctcacctgca
    28921 ctacgggtcc gcggaaggca tcgctgccgt tgagcggacc gtgccgctgg gccgcctcgc
    28981 gtcgccggac gagatcggcg cgtgcgcggt cttcctcgct tcaccgctgg cttcgtacgt
    29041 caccggctcg actttggtgg tgcacggcgg gggcgaggtg cccgcgttcc tggacgccgc
    29101 caagaccgat gggagttcat gatgttgtgc gaggaccggg tcgtcatcgt caccggcgcc
    29161 ggtcggggca tcgggcgtgc gcacgccctg gcgttcgcgg ccgcgggtgc cagggtcgtg
    29221 gtgaacgacc tgtcggtggg gcctgcgtcg gaagtggcgt cgttgatcgg gccgcgtgcc
    29281 gtggtgaaca ccgacgacgt gggcacctgg gccggtgccg cgcgggtggt cgaggctgcg
    29341 gtgtctgcct tcggcgggct cgacgtgctc gtgaacaacg cggggatcgt gcgcgaccgg
    29401 atggtcgtga gctgcggtga ggacgagtgg gacgaggtcg tgcgcgtgca cctcaagggc
    29461 cacttcgcgc cgctgcacca cgcggccgcg tactggcgcg gcgtccacaa ggcgggcggc
    29521 gcggtgtcgg gccgggtgat caacacgtcg tccggcgccg ggctgttcgg gagcgtgggg
    29581 caggcgaact actcgtcggc caaggcgggg atcgcggcga tgacgctcgt ggcggcggcc
    29641 gagctggcgc ggtacggcgt gacggtgaac gcgatcgctc ccgccgccag gacgcggatg
    29701 accgaagcga cgttcgcgga gtcgatggcg gcgccggacg gcgggttcga cgcgatggcg
    29761 ccggagaacg tgtcgccgct cgtggtgtgg ctgggcagtg cggaggctgc ggacgtgacc
    29821 ggccggatgt tcgaggtcga cggcgggcgg atctgcgtgg tccacgggtg gcagcgcggg
    29881 ccggagatcg acaagggtgc gcggtgggcg ccggacgagc tgggcggggt ggtgcgtcag
    29941 ctggtcgccg aggatcaccc ggtgcccgtg tacggggctt gagcgcggat gagctccagt
    30001 gcggcatcaa gcgcccggtc cgccggcacc gcgatgtccg ggacgacccc gacgccttgc
    30061 cagttgccgt tggtgatcgg gttgaccgat cgggattcgg ccaggcacaa cacgaagtgc
    30121 gggtgcagcc gccggtactc gaacggatgc gcgcctccgc cgctgggctc gcccaccaca
    30181 acggcccggc ccagcgcctg caggtcgtag gcgaagtgct cggcggcgga gaacgtcttc
    30241 ggggagatga ggacgtacac cggcttggtg gcgccgtacc ggcgccccgg gacccaggcc
    30301 ggggtgttgc tggtcgtgag ccggtcctcg gggcggtagt aggtgctgct caggggttcg
    30361 ctgcggtcga agaggtacgc cgcgagcagt gccaccatgt cgctgtggcc gccgccgttg
    30421 cgacgcagat cgatgatcat cgcgtcggcc tgggcgagca acgtcatggc ggcggcggcc
    30481 acatcgccgg ccatggccgg cggagcgaac acgcgcaggc tgaggtagcc gatgttgtcc
    30541 ggcagcagct cgaacttctc gaagccgtgg ttgacccgtc tgccgtagta gcgctccgcc
    30601 tcctgctccg agtaggcgtc gccggcggtg atctcgactg ccggcaacgc cgccgcggag
    30661 tagctcacgg ccaggtgccc atcgtcggaa ccctcccgaa gatgctcggt gagcgccgcg
    30721 gcgaactcac cggggtcgga gagcgcctgc cagcggtcgg cggcggcatc gtgccggagc
    30781 tgctgcgcca gcgaccggcc gacctcgatc gagacgtacc ggctctccat cagatcggcg
    30841 gcacgctcca gcacacggcg ccgatcctct gcgcccaccg tcgggcgttg cccagagacg
    30901 accaccgccg gaagctatca gggtctgaca gttccggtcc tcagatccgt tcgatgatcg
    30961 tgccgctggc cagtgccccg ccggcgcaca tcgtgatcag cgccgtcgtc gcgtcgcggc
    31021 gctccagctc gtgcaacgcc gtcgtgatga gccgcgtgcc cgtgctgccg accgggtgac
    31081 cgatcgcgat cgcgccaccg ttgacgttga cccggtccag gttcggccgg tgcaccgcgg
    31141 cccacgacag cacgaccgat gcgaacgcct cgttgacctc gaacaggtcg atgtcggcca
    31201 tcttcatacc gctgcgctcc agcagccgcg cggtcgcgtc gaccgggccg tcgaggaggt
    31261 agtacgggtc ggagccgacg aggcactgcg tgacgatccg cgccctcggc cgcagcccgt
    31321 gtgcgcgtgc ccagtcctcg tccacgacca tcacggccga ggcgccgtcg gagatctgcg
    31381 ag
//
