LOCUS       NZ_QGHB01000003        21005 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Lentzea atacamensis strain DSM 45480 Ga0215650_103, whole genome
            shotgun sequence.
ACCESSION   NZ_QGHB01000003
VERSION     NZ_QGHB01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea atacamensis
  ORGANISM  Lentzea atacamensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 674900)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 674900)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Expected Final Version            :: No
            Genome Coverage                   :: 90.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003148865.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:35:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,333
            CDSs (total)                      :: 9,254
            Genes (coding)                    :: 9,110
            CDSs (with protein)               :: 9,110
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 6 (5S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 32 of 144
            Pseudo Genes (incomplete)         :: 121 of 144
            Pseudo Genes (internal stop)      :: 2 of 144
            Pseudo Genes (multiple problems)  :: 11 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:50:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 159302
            Orig. end                         :: 180307
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QGHB01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21005
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21005
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21005
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11005](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11005
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    1869..1883
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            2687..3112
                     /locus_tag="C8D88_RS14705"
                     /old_locus_tag="C8D88_103158"
     CDS             2687..3112
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D88_RS14705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D88_103158"
                     /product="hypothetical protein"
                     /protein_id="WP_109635647.1"
                     /transl_table=11
                     /translation="MRRDVEGSTVNTPERSIGPLLAALCVRLPEADSPLTRDPELQAKV
                     RDIIGAVRKGGDDLDRLFEELDAAMRRAGFPRGLEPARVRVTGSYRPLSALDVHAVHMV
                     LRCPGDCPRIERSTPQTRLEPPICQVHDRRMRVERRR"
     gene            3109..3966
                     /locus_tag="C8D88_RS14710"
                     /old_locus_tag="C8D88_103159"
     CDS             3109..3966
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D88_RS14710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D88_103159"
                     /product="hypothetical protein"
                     /protein_id="WP_109635650.1"
                     /transl_table=11
                     /translation="MTGVLTTLGAKAAERWIALLALPGALFLAFVAATWLMRDGRLFDV
                     SPVVAELSRPHRPAASLVLLAAAVLVGAAGAGFVAQGLGALVQRLWFATRLGPPGWALT
                     ALRRWWWKRADDAYGDELVASNPDMRKLNLLLARRDRICPVQPDRPLWMADRLRAVGER
                     VHGTYGLDLGSLWPRLWLVVPDGVRTELSSARARLTDDARLCAWGLMYLVPALWWWPSA
                     VIAVGTCVVAWRRGRASCDTLSDLIESAVDLHAGAVVEHLGINAPEGLTRAVGDQVTER
                     LRKD"
     gene            complement(3995..5026)
                     /locus_tag="C8D88_RS14715"
                     /old_locus_tag="C8D88_103160"
     CDS             complement(3995..5026)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016698036.1"
                     /locus_tag="C8D88_RS14715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103160"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_109635652.1"
                     /transl_table=11
                     /translation="MTLQAELRVEQAGFTLDLDLTIEPGEVVALLGPNGAGKTTALRAL
                     AGLLASTSRIRHNGSTWDGLPAEKRPIGVMFQDYLLFAHMSALDNVAFGLRARGTRKAE
                     ANAVALRWLDQVGLADFAHARPRRLSGGQAQRVALARALATSPELLLLDEPLAALDAST
                     RLRVRSELGRHLQDYPGHTLLVTHDPLDAMVLADRLVILEHGRVVQEGSPRDVVRQPRT
                     DYVAHLVGLNFYRGVARGTEVLLDGGGTLTIAEPADGPVHVVFPPSAVSLYPAKPAGSP
                     RNTWQAVVSGIEQHAHTTRVDLDGSPAVLADITTATVAELRLQPGDALWVSLKATEIHT
                     YPR"
     gene            complement(5023..5808)
                     /gene="modB"
                     /locus_tag="C8D88_RS14720"
                     /old_locus_tag="C8D88_103161"
     CDS             complement(5023..5808)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="modB"
                     /gene_functions="transport (smcogs) SMCOG1214:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016698035.1"
                     /locus_tag="C8D88_RS14720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103161"
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="WP_109635655.1"
                     /transl_table=11
                     /translation="MRSRLPVVLVLPAVIGLVFLLVPLAGLLIKAPWATLPAQLFSQEV
                     GQALRLSLICASLATVVCLVLGVPLAWLLARSDLPGRGVLRALVTVPLVLPPVVGGVAL
                     LLVLGRRGVVGQYLDQWFGISLPFTTAGVVLAEAFVAMPFLVISVEGALRAADPRYEEA
                     AATLGASRWLTFRRVTLPGVMPGVIAGTVLCWARALGEFGATITFAGNFPGRTTTMPLA
                     VYLALETDPDAAIVLSIVLLLVSVAVLAGLRDKWISGPS"
     gene            complement(5805..6545)
                     /gene="modA"
                     /locus_tag="C8D88_RS14725"
                     /old_locus_tag="C8D88_103162"
     CDS             complement(5805..6545)
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0030973 - molybdate ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="modA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016698034.1"
                     /locus_tag="C8D88_RS14725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103162"
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_109635658.1"
                     /transl_table=11
                     /translation="MKRVLVLTLLLAGCGSPAATSTGGDITVFAAASLSESFTKLGTEF
                     EAAHPGSKVRFSFAGSSALAQQINQGAPADVFAAAAPANMKQVTDTGAVTATPATFARN
                     TLQIAVPRGNPGRVTGLADFAKADLKIALCAEQVPCGATAKKVFEAAGVKAAPDTLEQD
                     VKAVLTKVSLGEVDAALVYRTDVRAAGGKVEGEDFAEAAKAVNDYPVAPLAKAPNAPTA
                     KAFVDFVLSGRGREVLIEAGFSAP"
     gene            complement(6542..6946)
                     /locus_tag="C8D88_RS14730"
                     /old_locus_tag="C8D88_103163"
     CDS             complement(6542..6946)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005466441.1"
                     /locus_tag="C8D88_RS14730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103163"
                     /product="molybdopterin-binding protein"
                     /protein_id="WP_109635661.1"
                     /transl_table=11
                     /translation="MPNLRISEAAALLGVSDDTLRRWIDQGRLRSVVLDNGRKGVSGTE
                     LAEFAQHLTEVAEPGTTVAASARNRMKGIVTRVIKDGVMAQVDMQAGPFRITSLMSRES
                     ADELGLEVGSVAVASIKSTHVVVEIPEASS"
     misc_feature    6900..6913
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            7138..8202
                     /locus_tag="C8D88_RS14735"
                     /old_locus_tag="C8D88_103164"
     CDS             7138..8202
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1282:
                     extracellular ligand-binding receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF024850.5"
                     /locus_tag="C8D88_RS14735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103164"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_170154880.1"
                     /transl_table=11
                     /translation="MKIGYLNNASGAFAVPELQIGAEVAVAHLNRNGGVRNRPFELVTC
                     PTDGTPEQSHQCAEKFAGEKVAVVVQGVDTGADAAMPVLSAAAIPLVGHVQFTPGLMNH
                     KNAFFFGAAAVAYGTAALKYYADQEVKTVAWLLPESPATHAFTDTVLAPAAKRFGLSYR
                     SVYYPAGSPDWAGLARAVKTAEASGSIAATEEQCTHIVRALREAGYAGRILAASCTGLP
                     ESVGNQSIGVELSSDFWHPTDPLSAPPANQVEIEEYRTAMKAAGHDEPVAGAVMSFADI
                     MTLARVLSTSDGTPEQALRAVKNLDSFLGPQITCDHTWFGNSACSTAVLFYRFQPNGAL
                     KAQVPDFIEVAKLG"
     gene            8247..8402
                     /locus_tag="C8D88_RS46760"
                     /old_locus_tag="C8D88_103165"
     CDS             8247..8402
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D88_RS46760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D88_103165"
                     /product="hypothetical protein"
                     /protein_id="WP_170154881.1"
                     /transl_table=11
                     /translation="MNEFRDNLLARIEQAEEAVRQAVEQQDAYAEEVHSADLANLRRLA
                     AEHGVG"
     gene            8406..8738
                     /locus_tag="C8D88_RS14740"
                     /old_locus_tag="C8D88_103166"
     CDS             8406..8738
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005438525.1"
                     /locus_tag="C8D88_RS14740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103166"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_109635667.1"
                     /transl_table=11
                     /translation="MPVPLYQAKAEFFRMLGHPVRIRVLELLQDGPKAVRELLAEIEVE
                     PSSLSAQLAVLRRSGIVTATREGSTVVYALAGADVADLLRAARRILTELLVGRNELLVQ
                     LREEPA"
     gene            complement(8859..9824)
                     /locus_tag="C8D88_RS14745"
                     /old_locus_tag="C8D88_103167"
     CDS             complement(8859..9824)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018331203.1"
                     /locus_tag="C8D88_RS14745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103167"
                     /product="aldo/keto reductase"
                     /protein_id="WP_109635671.1"
                     /transl_table=11
                     /translation="MRYTKLAGMDVSEICLGMMSYGDPSLGNHPWSMPEEESRPFIKAA
                     IEAGINFFDTANVYSAGSSEEITGRALKDFARREEIVLATKVHGRMRPGVNGAGLSRKA
                     IFAEIDASLQRLGTDYVDLYQIHRFDASVPLEETLEALHDVVKSGKARYIGASSMYAWQ
                     FAKALFTQRQNGWTRFVSMQNHYNLLYREEEREMLPLCADQGIAVIPWSPLARGRLTRD
                     WDATTARTETDEFGSTLYVESDRAIVEQVASVAAARGVSRAQVALAWLLRNPVITAPIV
                     GVTKPHHLDDAVAALEFELTDDEVRLLESAYEPHRIAGHA"
     misc_feature    complement(9838..9852)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.52"
                     /tool="antismash"
     gene            10001..11005
                     /locus_tag="C8D88_RS14750"
                     /old_locus_tag="C8D88_103168"
     CDS             10001..11005
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.5"
                     /locus_tag="C8D88_RS14750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103168"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_109635674.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-24, bitscore:
                     81.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSIDVVAPPRAVLAWSRAMIDAPLKAAFAALPDETREVVEYHRS
                     DFSTAALALLAADAVGDAIPAIRVATAVELAHQHEQLHADLMTRALSRGHQPSAWVEFG
                     DDRAVSAADALISLAFAQLTRPEVMILNAALLSVVDGYVQEAEMDERDDVDIAEYLGVA
                     AAKHSALTACACELGALAAGAVRSQAVHLREFGDDVGLARKHVDDVLAIWGGAPVSGRP
                     LYDDLAHRRRTLPVVAAINAGTDVYATDAEPRELALRVERAGGRKWCEQQAELLLARAL
                     NHLRQAGPRARAAEDLSGLAREITTARFAPARTPAPAVPSQSTAASREDRTPS"
     gene            complement(10911..11546)
                     /locus_tag="C8D88_RS14755"
                     /old_locus_tag="C8D88_103169"
     CDS             complement(10911..11546)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013530.5"
                     /locus_tag="C8D88_RS14755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103169"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_325051039.1"
                     /transl_table=11
                     /translation="MVHLAAIPGPGVAPNARTFHNNVTSTYNVFAAARLAGVRNVVWAS
                     SETVLGLPFDTPPPYIPIDEEYAGRPETSYSLGKLVDETLAQQFCRWEPEMKIIGLRFS
                     NVMEPHDYERFPFDADPLARKWNLWSYIDARDGAQAVRKALAHDATGFDVFIIANADTC
                     MTTPNDELVAKVYPGVPLKREFGPHETLLSIEKARRVLGFEPVQTWRS"
     gene            complement(<11641..11763)
                     /locus_tag="C8D88_RS49670"
                     /pseudo=""
     CDS             complement(<11641..11763)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013530.5"
                     /locus_tag="C8D88_RS49670"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTQRVAVTGGSGKLGRAVVADLLEHGWEVHNLDQAAPPADQ"
     gene            complement(<11861..12325)
                     /locus_tag="C8D88_RS49675"
                     /old_locus_tag="C8D88_103170"
                     /pseudo=""
     CDS             complement(<11861..12325)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024989.5"
                     /locus_tag="C8D88_RS49675"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103170"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MATWSASSTTSGSERARRCWCTGPQGSWVSSAFSSRWPAAPRSSV
                     PPPPATTTTCALSARSPSPTVAASPTASVRQHRRASTPCSTPPGRVTWRCRSNCATSTD
                     RIITIADPRAAELGVTFSAGSRPFGAELAEYARLAADGKLVVRVAESLPLV"
     gene            complement(12335..12922)
                     /locus_tag="C8D88_RS14765"
                     /old_locus_tag="C8D88_103171"
     CDS             complement(12335..12922)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF047071.1"
                     /locus_tag="C8D88_RS14765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103171"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_109635676.1"
                     /transl_table=11
                     /translation="MRTQHEIGTRERIVRATSRLIQRQGYEATGLKQISQEAEATLGSV
                     YHFFPGGKRELAVEAIGHGDREFAEFLREAFEREEDPAAALVACTRELAEGLRESDWLD
                     GCPVTTAALESAGREPEIQQAAENAYENWRALVRAKLERSGFAADVAHDLAHSVINLLE
                     GAELSAQVSRSTAPLEIAGRHLAVLVEAYRPR"
     misc_feature    complement(12942..12955)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.69"
                     /tool="antismash"
     misc_feature    complement(12976..12989)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            13002..13859
                     /locus_tag="C8D88_RS14770"
                     /old_locus_tag="C8D88_103172"
     CDS             13002..13859
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF044865.2"
                     /locus_tag="C8D88_RS14770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103172"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_109635679.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2e-07, bitscore:
                     25.8, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSVTVIGMGPMGQAMAGAYLDKGYEVTVWNRTPARADELVVRGA
                     ARAGSVEAALTASDLVVLSLIDHDAVDAVLAQAPETALAGRVFVNLTSDTPDRMRATAA
                     WLAERGAVQLAGGVQVPPPGIGTPEAMTYYSGPEEVIESRRADLEVLTGVHYLGADQGL
                     APLYYQIGIDMFWTALAGYLHGQAVAEANGISADEFLPHAVRTLDLRYFLEFYAPRITA
                     GHHEGDVDRISMGVASVEHVVRTAEAAGVDGSLPAAVLELFRRGVAAGHGQRSLTSLVE
                     VLKA"
     gene            13959..14849
                     /locus_tag="C8D88_RS14775"
                     /old_locus_tag="C8D88_103173"
     CDS             13959..14849
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100386.1"
                     /locus_tag="C8D88_RS14775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103173"
                     /product="endo alpha-1,4 polygalactosaminidase"
                     /protein_id="WP_233439431.1"
                     /transl_table=11
                     /translation="MGGRRFRVLVIVLVTMLTSVSSACADDSPLPGGFVYQLQGYPGGR
                     LDELAAAPFRTAVVDLARDAGSSYFRADEIGRLKASGKRVLAYFEIGSIEEFRPDYAAI
                     RAERLLLNEWPSWPGEHFVRYWEPGWWELAVRPRLDRALAAGFDGVYLDTPLAYEEIDL
                     ALLPGTDRVALAGRMTDLIVRISAHVKRLNPAFGVYPQNSPELREYPGYLDAIDGIGME
                     ELFFRATDEPCTADFCAANLAQTRKLKEAGKTVLAVDYATRAENVAEACRRYREEGFEG
                     YVTVRALDTVAAPCR"
     misc_feature    complement(13987..14007)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.14"
                     /tool="antismash"
     misc_feature    complement(14891..14905)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.44"
                     /tool="antismash"
     gene            14911..16191
                     /locus_tag="C8D88_RS14780"
                     /old_locus_tag="C8D88_103174"
     CDS             14911..16191
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1152: nucleotide sugar dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100385.1"
                     /locus_tag="C8D88_RS14780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103174"
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="WP_233439432.1"
                     /transl_table=11
                     /translation="MGIIGMGYVGLTLAAAMARRGYEVHGVDTQPALLETLSNGRPHIF
                     EPGVEDVFQEWVGRRIFLSHDLPDSGVDAAIICVSTPVGESGREPYLLNLAAAAEHIGK
                     RCAPGTLVVVRSTVPVGATRSVVLPKLAEAWGSARLVMAPERTIQGQALRELVELPQVV
                     GGLDDESLRLGLELFGGLSAQLVPVSTLETAELVKLVNNCHTDVIYSFGNEVARLTERL
                     GLDPLEVIRATNADYPRPDICKPGYVGGGCLSKDPYLLLSAAEQAGYVPRLIKSARGVN
                     EDLPVHVAERVIEMMGEPEGKRLLVLGWAYKGWPPTDDMRGTPIASMMPGFTEAGVQVL
                     GHDPLVDGDVIRRYGGTPVDVEAGFASADAVLVITDHPEYRRLDVGRLLPGSGVRLVYD
                     SWRVLSERDVTGHGIRYAALGYEPEVA"
     gene            16192..17142
                     /locus_tag="C8D88_RS14785"
                     /old_locus_tag="C8D88_103175"
     CDS             16192..17142
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (56-186). E-value:
                     4.1e-09. Score: 27.8. Matches aSDomain:
                     nrpspksdomains_C8D88_RS14785_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100384.1"
                     /locus_tag="C8D88_RS14785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103175"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_109635681.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 7.4e-18, bitscore:
                     59.9, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 3.5e-06,
                     bitscore: 21.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLVLGGAGFIGLHLTRRLLADGHEVTVVDDFSRGRRDPELEAL
                     DVPVISADLTDPASFAALPRDCDDVYLLAAVVGVRNVERDPARVVRINTLAVLNTLDWI
                     TPRQRLFFASTSETYAGGVGTGLVPVPTPETVPLVVEDVTAPRFAYGVSKMLGEAAVIH
                     TGRAKGVPVVVGRFHNVYGPRMGADHVIPELCLRALRREDPFTVYGTDQFRAFCHVDDA
                     VEAVVGLMRTEKAAHQIVHIGDDTAETNIGELAELVLKIAGHAPSVHRAAAPPGSVARR
                     CPDLTLLRGLTGYRPRVALDEGVRRTFDWYRADQF"
     aSDomain        16360..16749
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8D88_RS14785_NAD_binding_4.1"
                     /evalue="4.10E-09"
                     /label="C8D88_RS14785_NAD_binding_4.1"
                     /locus_tag="C8D88_RS14785"
                     /protein_end="186"
                     /protein_start="56"
                     /score="27.8"
                     /tool="antismash"
                     /translation="PASFAALPRDCDDVYLLAAVVGVRNVERDPARVVRINTLAVLNTL
                     DWITPRQRLFFASTSETYAGGVGTGLVPVPTPETVPLVVEDVTAPRFAYGVSKMLGEAA
                     VIHTGRAKGVPVVVGRFHNVYGPRMG"
     gene            complement(17198..18097)
                     /locus_tag="C8D88_RS14790"
                     /old_locus_tag="C8D88_103176"
     CDS             complement(17198..18097)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100383.1"
                     /locus_tag="C8D88_RS14790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103176"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_211337266.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.6e-08, bitscore:
                     29.3, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVLLFGASGYLGRAAGEELHARGARVVRVTRTVPGEDGWVRHDL
                     VRSSSGELVGLLRSVRPDVVVNCTGLLDGTTSELVTANVTPTAALLDAIPQAVPRARLV
                     VLGSAAEYGRVREGSAVAEDAAANPVSAYGITKLASTLLVRDAVAAGRLDAVALRIFNP
                     IGPDLPAGTVLGRAAEAIRAAMREGDDITLGPLGSYRDFVDVTDVASAIADAALAPGLG
                     EPVLNVGSGQAVAVRQVVAMLAEVAGFRGRVRETAPVQSRSGAVTWIAADTSRAHRALG
                     WSPHHDLADSVRSLWQHS"
     gene            complement(18094..18837)
                     /locus_tag="C8D88_RS14795"
                     /old_locus_tag="C8D88_103177"
     CDS             complement(18094..18837)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100382.1"
                     /locus_tag="C8D88_RS14795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_103177"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_146231500.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 9.4e-11, bitscore:
                     37.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHAVILAGGRGVRLRPYTTALPKPLVPIGEEYAILDIILQQLGRR
                     HFDRVTLAIGHLGSLIRAFVGDGSRWNIRVDYAEEKMPLSTIGPLLNIVDLLPEHFLVM
                     NGDVLTDLDYEALLGHHITCGAPLTVATYQRKVKIDFGTLSTEEGRIVSFVEKPELSYG
                     VSMGVYAMTRKTLTPYPRNVPFGLDELVLDLLARGEEPAAYEFGGYWLDIGRPDDYDEA
                     NRNFEQLRPALLPGSVRHNAMDVTS"
     gene            complement(18851..20164)
                     /locus_tag="C8D88_RS14800"
                     /old_locus_tag="C8D88_103178"
     CDS             complement(18851..20164)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D88_RS14800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D88_103178"
                     /product="hypothetical protein"
                     /protein_id="WP_109635686.1"
                     /transl_table=11
                     /translation="MILDELVERVASLLPDPVDELQVAALLESQGITDQVAVDRYGRAD
                     VFALGQEVFERLPRGSVAVEDHSPGTTWLHAVRGPLYLVPTTVFPAVAAVLGGPAAVRA
                     MVVATAVSWVWGSGASAVAHRLLSGGAAATAARSLRWLGAAGTAVAATTAAAVLGWWSA
                     LFVLALAGLQFAIGVLLFHREEVRLAVAVLPAGAGGVLFLVSEVVGIALVLGGVTVLLA
                     VGGAWRAGRAARDSGGVRPPRALTLLGTALPSSVYAALCAILLLYTDSRYVLSALDLAV
                     AAAPLVLGMGVVEWRAHRFFELATQELRRCALPADFHQAIWRGLLRELGFCLTALGAAA
                     LVLLVALRVSGVLTSPGALLIDGHVLLGGAFFLGFVLVRTSGPLPAPLIVSAALLGDVT
                     AVALGADPVPAFLITCTALSIFLLVALRGSVGQVRHYR"
     misc_feature    20306..20321
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.27"
                     /tool="antismash"
     misc_feature    20415..20429
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.13"
                     /tool="antismash"
ORIGIN
        1 ctcggcgagt tccggagcgg cgatctccag gtcgtccagg gagttcctgc ccagctgcga
       61 ccacagcacg ccgcgtgctc tctcgaacaa ctgcaccgcg agcaccggat caccggcgcg
      121 cacggcggcg acggcggcgt ccgacggcag gtcggcggcg gcggccagcc ggaactcctg
      181 gtccgcgcgg gcgagcgtgc gcggcgccag cgcggagagc aggccgaccg cgagcgcgaa
      241 gccgtcggcc gcctcctgcc actgaccgag cgtcgccgcg gcggccccgc tgatgcgggc
      301 ggccgcgagc cggccgggca ccggcaccgt ctcgttcccg gcgatggcgc gggcgagctg
      361 catcgacgag accagcgcat ccgtgtcccc gtcgagtttt ccgcgttcgt agcggaggga
      421 ggcgagctcc agcgaaccct ccgggtgcag cgactccgcc tccctggcga gtgccgtgtc
      481 ccggcgcagc aggaacagtt cggtgagcag acctgccagc gcggcgtcgt tgccggagtc
      541 gcgcgaccgc aacgcgggtg accggcgcag cgcgatcgcc cgttccagcc gcacggcacg
      601 gtcctctccg accggggtgg cgagcacccg cgcgaggctg agctccgtgc tcacccgaga
      661 gtcttctgtg ggctcggcga cggcctgctc cgccagccac agcgcctccg tcatcggcgg
      721 ctgcgcggcg gtgcgggccg cgagcatcgc cagccgctcc gcgagtgccg ctctcgcctc
      781 ggcgatcagc ggatggcccc gcggcaggtc ggcctcgacc gtcctggaca gctcgatcgc
      841 cgcgtcgaga tcgctcaacg tgtcctgggc gcgatagcgc gacgtgagca tggtcgcgag
      901 gttgccgcgg atctcgtgca cccgcatcca ctggtggccg tgttccgccg cgcccgcgag
      961 cgcggcccgg ctgagttcga tcgcctcgtc cagatcggtc gaaggaccgc cgccgcggta
     1021 ccgggtggcg agagcggcgg cgaggttcac gagcgcgatg tgccggttga tgtggcccgg
     1081 tggcaacttc gcggcctcgc gcagcaaggc gatgccctcg tcgaggccgg gtgatctcgc
     1141 gccgtgcgcg atcagcagca cctgcccgag cacgcccgcg gcctccagcg cggcctcgct
     1201 gccggcggca gccgcgctct cggcccgacg ggcgacggtc tcggcctcga ccagatcgcg
     1261 ggggacgcgc gtctcgtcgt agcggtccgc gagcaggctt gccagcatga tcgtcccggt
     1321 gcccggccgc ttgcgctcgt ggcgggcgag cgaccgcaac acggtgatcg cctcgtcgcg
     1381 atcggcggtg cccgcgaggt gctggtaccg ggcgatcagc gtggacgcca gcacgaacag
     1441 gcagtgggaa cgggcgctgt gccaacgagg gcagcgccgc accgccgcgc gcgcgaggtc
     1501 gatggaccgg tcgacgaaaa cggccctgcg gcggttgtgg aaccggtcgc ggtagaccac
     1561 ggccaactcg gcgaacaggc gcgcgcgtgc ccccggcttc caccaaggtg tccgctccat
     1621 gtcctccgcg atcgcggcga tggtcatctc gacgaagttc acggtggcgg accgcacggg
     1681 ctcgccgacg ccgtcgatgt cgtggtcgac cacgttcgcc gtgccgccgg gcccggcatc
     1741 ggccagtacg agcaggtccc tgagctcacg tccgccagtg cggctcatca gcgccttgcg
     1801 ggcgagtgcc agagccagat gggagtagtg cagcgtgccc tcctcggtgg cgacgctgat
     1861 gaggatgtgg aggtagtcgg ccagttgctc tgcccggtcc tctaccgacg gcccggccga
     1921 ggactccacg tgcgacctct ggatgctgag ctccagcagc gactccgctt cgtcgagcgc
     1981 gtcgatgtca ccggtgacgg cgaacagcat cgcgagcgcg attccgagct cgcgcagcaa
     2041 ctcgtcgatc atctcctcgc cgggcctcgc cgccgcgacc gcttcccggc gcagctggac
     2101 caggtacggg accagcgggc cgttcgaggt cgcgccgacc agcgcctgca ccatgcgcgc
     2161 gagcgagtcc agcgcgaacg gcctgagctc gccgtcgggc cgggtccaga gcatgccgag
     2221 gttcaccatg ctcgtcagga cgacgaggcg ggagatgtcc tcttcggacc tgtcacagct
     2281 cagctgccgg tacagccgtt cggcgccgat gacgagcttg ccggggtggt agagcgcctc
     2341 cggtgcggcg ggctcgacgt catcgggtag ctcgacctgc cggacgaagg cgagttcagg
     2401 tggttcggcg tcgggaaacc cgtgcagcag cgtgaccgcc acgatgaggt cgtcgggcag
     2461 gaacggctgc atcgcggcga catgccgggc ccaggcgagg cgtcccgcgg ccagtgcggc
     2521 ctcgggttgc tcgccgtgca gcacgagcag gcggtcgtag atctcctgcg cctcgggagc
     2581 gaacaggtcg tcctgtgccg acaaccggcc ggcggcggcg atcagatccg gtaggtccac
     2641 cgatcttgct cctcggcgtt gtcgaaggca ttctcagcct acggtcgtgc gccgcgacgt
     2701 ggagggctca acggtgaaca cacccgaacg cagtatcggc ccgctgctcg ccgcgttgtg
     2761 cgtgcggctg cccgaagcgg acagcccgct gacccgtgat ccggagctgc aagcgaaggt
     2821 gcgggacatc atcggcgctg tgcgcaaggg tggtgatgat ctcgaccggc tgttcgagga
     2881 gctcgacgcc gcgatgcgac gggccggatt tccacgcggc ctggaaccgg cgagggttcg
     2941 cgtgacaggg tcgtaccggc cactgtccgc tctggacgtg cacgccgtcc acatggtgct
     3001 gcgctgcccc ggcgactgcc cgcgcatcga gcgcagcacg ccgcagacgc gcctcgaacc
     3061 accgatctgt caggtgcacg accgccggat gcgagtggag cggcggcgat gaccggcgtg
     3121 ctgaccacgc tcggtgccaa ggcggccgaa cggtggatcg ccctgctggc gttgcccggc
     3181 gcgttgttcc tcgccttcgt cgccgccacc tggctgatgc gcgacgggcg gctgttcgac
     3241 gtctcgccgg tggtggcgga gctgtcgcgg ccccaccgcc cagccgcctc gctcgtgctg
     3301 ctggccgcgg cggtgctcgt cggcgcggcc ggggcgggtt tcgtcgcgca gggcctgggc
     3361 gcgctcgtgc agcggctgtg gttcgcgacc cggctcggac cgccgggctg ggcgctgacg
     3421 gcgttgcgcc ggtggtggtg gaagcgggcc gacgacgcct acggggacga gctggtcgcg
     3481 tcgaaccccg acatgcggaa actcaacctg ttgctcgcca ggcgtgatcg catctgcccg
     3541 gtccagccag atcgtccact gtggatggcc gaccggttgc gggcggtcgg cgaacgcgtg
     3601 cacgggacgt acggcctcga cctcggctcg ctctggcccc ggctctggct ggtcgtcccg
     3661 gacggtgtcc gcacagagct ctcgtcggca cgggcacgtc tgaccgacga cgcccgcttg
     3721 tgcgcgtggg ggttgatgta tctggtgccc gcgctgtggt ggtggccgtc agcggtgatc
     3781 gcggtgggga cctgtgttgt ggcgtggcga cgcggcaggg cgtcctgcga cacgttgtcc
     3841 gatctgatcg agtcggccgt cgacctgcac gccggtgccg tcgtcgagca cctcggcatc
     3901 aacgctcccg aaggcctgac gcgcgccgtc ggtgatcagg tcaccgaacg cctccgcaag
     3961 gactagcggg cacttcgcgg cgctttcgtg tgaactaacg cggataggtg tggatctccg
     4021 tcgccttcag cgaaacccac agcgcgtcgc cgggctgcag ccgcagctcg gcgaccgtcg
     4081 ctgtcgtgat gtcggcgagc acggcggggg agccgtcgag gtcgacgcgg gtcgtgtggg
     4141 cgtgctgttc gatgccggaa acgacggcct gccacgtgtt gcgcgggctg cccgcgggtt
     4201 tcgcggggta caggctgacc gcggacggcg ggaacaccac gtgcacgggg ccatccgccg
     4261 gctcggcgat ggtgagggtg ccgccgccgt cgagcagaac ctcggtgccg cgggcgacac
     4321 cccggtagaa gttcaggccg acgaggtggg cgacgtagtc ggtccgcggc tgccggacga
     4381 cgtcacgcgg cgagccctcc tgcacgaccc ggccgtgctc caggatgacg agccggtcgg
     4441 cgagcaccat cgcgtccagc gggtcgtggg tgaccagcag cgtgtggccg gggtagtcct
     4501 ggaggtgcct gcccagttcg gatcgcacgc gcagccgggt gctcgcgtcc agtgccgcca
     4561 ggggttcgtc gagcagcagc agttccggtg acgtcgccag ggcgcgggcg agggcgacgc
     4621 gctgggcctg gccgccggac aaccggcggg gcctggcgtg ggcgaagtcc gccaggccga
     4681 cctggtccag ccagcgcagc gcgacggcgt tggcctcggc cttgcgggtg ccgcgggcgc
     4741 gcaggccgaa cgcgacgttg tcgagcgcgc tcatgtgcgc gaacagcagg tagtcctgga
     4801 acatcacgcc gatgggccgt ttctcggcgg gcagaccgtc ccaagtggac ccgttgtgcc
     4861 ggatgcggct cgtgctggcc agcagtccgg cgagggcgcg cagggcggtg gtcttgcccg
     4921 cgccgttggg gccgagcaac gccacgacct cgcccggttc gatcgtgagg tcgaggtcga
     4981 gggtgaagcc cgcctgttcg acgcggagct ctgcctgcag cgtcatgacg gcccgctgat
     5041 ccacttgtcg cgcagccccg caagcaccgc gacggagacc aggagcagca cgatgctgag
     5101 cacgatcgcg gcgtccgggt cggtctccag cgccaggtac acggcgaggg gcatggtcgt
     5161 cgtcctgccg gggaagttgc cggcgaacgt gatcgtcgcg ccgaactcgc cgagcgcacg
     5221 cgcccagcac agcacggttc ccgcgatgac gcccggcatg acgccgggca gggtcacgcg
     5281 gcggaacgtc agccagcgcg aggcgccgag cgtcgccgct gcctcctcgt aacgcggatc
     5341 cgcggcgcgc agcgcacctt cgaccgagat gaccaggaac ggcatcgcca cgaacgcctc
     5401 ggcgagcacg acgcccgccg tggtgaacgg cagtgagatc ccgaaccact ggtcgaggta
     5461 ctggccgacc actccgcgcc ggccgagcac cagcagcagc gccacaccac ccaccaccgg
     5521 cggcaggacc aggggcacgg tgaccagcgc ccggagcaca cctcgtcccg gcaggtcgct
     5581 gcgcgcgagc aaccacgcca gcggcacgcc gaggacgagg cacacgaccg tggcgagcga
     5641 agcgcagatc aacgagagcc gcagcgcctg cccgacctcc tggctgaaga gctgggccgg
     5701 cagcgtcgcc cagggtgcct tgatcagcag tcccgccagc ggcacgagca ggaacaccag
     5761 cccgatcacc gcgggcagga cgaggacgac cggcagcctg gacctcacgg cgcgctgaaa
     5821 cccgcctcga tgagcacctc gcgaccgcgg ccggacagca cgaagtcgac gaaagccttg
     5881 gcagtaggag cattcggagc cttcgccagc ggtgcgacgg ggtagtcgtt gaccgctttg
     5941 gccgcctccg cgaagtcctc gccctcgacc ttgccgcccg ccgccctcac gtccgtgcgg
     6001 tagacgagcg ccgcgtcgac ctcacccagc gacaccttgg tcagcacggc cttcacgtcc
     6061 tgctccagcg tgtccggcgc ggccttcacg ccggccgcct cgaagacctt cttcgccgtc
     6121 gccccgcacg gcacctgctc cgcgcacagc gcgatcttca ggtccgcctt ggcgaagtcg
     6181 gcgagtccgg tgaccctgcc cggatttccc ctgggcacgg cgatctgcag cgtgttcctc
     6241 gcgaacgtcg ccggcgtcgc cgtgaccgcc ccggtgtccg tcacctgctt catgttggcc
     6301 ggagccgcgg ccgcgaacac gtccgccggc gcgccctggt tgatctgctg cgccagcgcc
     6361 gagctgcccg cgaagctgaa gcgcaccttc gaaccggggt gcgcggcctc gaactccgtc
     6421 cccagcttcg tgaacgactc gctgagcgac gccgccgcga acaccgtgat gtccccaccg
     6481 gtgctcgtcg ccgccgggga accgcagccc gccagcagca gcgtcagcac gagaacgcgc
     6541 ttcaactcga ggcctccggg atctcgacga cgacgtgcgt ggacttgatc gaggccacgg
     6601 cgacgctgcc cacttcgagg ccgagctcgt ccgcggactc acggctcatc aacgacgtga
     6661 tgcggaacgg cccggcctgc atgtcgacct gggccatcac gccgtccttg atgacgcgcg
     6721 tgacgatgcc cttcatccgg ttgcgtgccg atgccgcgac cgtcgtgccc ggctccgcca
     6781 cctcggtcag gtgctgggcg aactcggcga gttctgtccc gctgacaccc ttgcgcccgt
     6841 tgtcgagcac aacggaccgc aggcggccct ggtctatcca ccggcgcagg gtgtcgtcac
     6901 tgaccccgag caacgcggcg gcctcactga tccgcagatt cggcacgaac gggagcttat
     6961 atccgcgtct gcggaactct caaccgtgcg gatcgtaggt gtcgagggaa cccgacttat
     7021 cggtggcatc tcagctggcg accatcggcg gccatgcact caaggacctt ggtcgccgtc
     7081 ttccttctgg tcaccggatg tgccgccggg ccgcagaaag gcccaggcgg agaacccgtg
     7141 aagatcgggt atctcaacaa cgcgtccggc gccttcgcgg tgccggagct gcagatcggt
     7201 gccgaggtcg ccgttgccca cctcaaccgc aacggcggcg tgcgcaaccg tcccttcgag
     7261 ctcgtcacct gtcccacgga cggcacgccg gagcagtcgc accagtgcgc ggagaagttc
     7321 gccggcgaga aggtcgcggt cgtcgtgcaa ggtgtggaca cgggtgccga cgccgcgatg
     7381 cccgtgctga gcgcggctgc catcccgttg gtggggcacg tgcagttcac gccaggtctg
     7441 atgaaccaca agaacgcctt cttcttcggt gccgcggcag tcgcgtacgg cacggcagcg
     7501 ctcaagtact acgccgacca ggaggtgaag acagtcgcgt ggctgctgcc cgagtctccg
     7561 gccacgcacg ccttcaccga caccgtgctc gccccggccg ccaagaggtt cgggctcagc
     7621 taccgctccg tctactaccc ggccggcagc ccggactggg ccggcctcgc gcgggccgtg
     7681 aagaccgcgg aggcgtcggg cagcatcgcc gccaccgagg agcagtgcac ccacatcgtc
     7741 agggcgttgc gggaagccgg ttacgccggg cggatcctcg cggcgtcgtg caccggcctg
     7801 ccggagtccg tcgggaacca gtcgatcggg gtcgagctgt cgtccgactt ctggcacccc
     7861 accgatccgc tgtccgcgcc gcccgccaac caggtggaga tcgaggagta ccgcacggcg
     7921 atgaaggccg ccgggcacga cgaacccgtt gcgggcgcgg tgatgtcgtt cgcggacatc
     7981 atgacgctcg cgcgagtgct gtccacttcg gacggtacgc cggaacaggc cctgcgggca
     8041 gtgaagaacc tcgacagctt cctcggcccg cagatcacct gcgaccacac ctggttcggc
     8101 aactccgcgt gcagcaccgc cgtcctgttc taccggttcc agccgaacgg ggccctcaag
     8161 gcccaggtcc ccgacttcat cgaggtcgcc aagctcgggt agcctgccga attgaagact
     8221 tcttcaattc gacaggtcgt gatgccgtga acgagttcag ggacaacctc ctcgcccgca
     8281 tcgagcaggc cgaggaagcc gtgcggcagg cggtcgaaca gcaggacgcc tacgccgagg
     8341 aagtgcacag cgccgacctc gccaacctca ggcgcctggc cgccgagcac ggggtgggct
     8401 gaccggtgcc ggtcccgctg taccaggcga aggccgagtt cttccggatg ctcgggcacc
     8461 cggtgcgcat ccgggtgctg gagctgctcc aggacgggcc gaaagcggtg cgcgagctgc
     8521 tcgccgagat cgaggtcgag ccgtccagcc tctccgcgca gctcgccgtg ctgcgaagat
     8581 cggggatcgt caccgcgacc cgcgagggtt cgaccgtggt gtacgccctc gcgggtgccg
     8641 acgtggccga tctgctccga gccgcgaggc gcatcctgac cgagctgctg gtggggcgga
     8701 acgagctgct ggtccagctc cgcgaggaac ccgcgtgagc ttcctgccga cgacccggac
     8761 cgggagctcc gtagcgaacg tgatcacacc gatgttcgcc accacacccg aagccatcga
     8821 ccacgcgcgc caccaactgc gccgggccgg agtgttgcct acgcgtgccc ggcgatgcgg
     8881 tgcggctcgt acgccgactc gagaagccgc acctcgtcgt cggtcagctc gaactccagc
     8941 gccgccaccg cgtcgtccag gtggtgcggc ttcgtcacac cgacgatcgg tgcggtgatc
     9001 accgggttgc gcagcagcca cgccagcgcg acctgggccc gtgacacacc acgcgcggcg
     9061 gcgacggacg ccacctgctc gacgatcgcg cggtccgact cgacgtacaa ggtggacccg
     9121 aactcgtcgg tctcggtgcg ggcggtcgtg gcgtcccagt cgcgggtcag gcggccgcgg
     9181 gcgagcgggc tccacgggat cacggcgatg ccctggtccg cgcacaacgg cagcatctcg
     9241 cgttcctcct cgcgataaag gaggttgtag tggttctgca tcgacacgaa gcgcgtccag
     9301 ccgttctgcc gttgcgtgaa caacgccttg gcgaactgcc acgcgtacat ggacgaggca
     9361 ccgatgtagc gcgccttgcc ggacttcacc acgtcgtgca gcgcttcgag cgtctcctcc
     9421 agcggaacgg acgcgtcgaa gcggtggatc tggtacaggt cgacgtaatc cgtgccgagc
     9481 cgctgcagcg acgcgtcgat ctcggcgaag atcgccttgc gggacaaccc cgcgccgttc
     9541 acgccggggc gcatgcggcc gtgcaccttc gtcgcgagca cgatctcctc gcggcgggcg
     9601 aagtccttca acgcacgccc ggtgatctcc tccgacgaac cggccgaata gacgttggcg
     9661 gtgtcgaaga agttgatccc ggcttcgatc gcggccttga tgaacggccg ggactcctcc
     9721 tccggcatcg accacggatg gttgcccagc gatggatctc cgtagctcat catgccgagg
     9781 cagatctcag acacgtccat gccggcgagc ttggtgtaac gcacggtcag cccttcagga
     9841 aaacgacggt cacggtcggg tgatggtggc aacaacccgt tcaacatcaa cgtagtcgcg
     9901 ctcgccggat cgtgcctctc ttcaacacga cagtggcaat cacgcctcca cacctgacct
     9961 gcgggtttag cgtctcctcc cgaggtccga gaggaggcgc atgacgagca tcgacgtggt
    10021 ggcgccgccg cgggccgtgc tggcctggag ccgcgcgatg atcgacgcgc cgctcaaggc
    10081 cgcgttcgcc gcactgcccg acgagacccg cgaggtcgtc gagtaccacc ggtcggactt
    10141 ctcgacggcc gcactcgcgc tgctcgccgc cgacgccgtc ggcgacgcca tcccggcgat
    10201 ccgcgtcgcc accgccgtcg aactcgccca ccagcacgaa cagctgcacg cggacctgat
    10261 gacccgtgca ctcagccgcg gccaccagcc gagcgcgtgg gtggagttcg gcgacgaccg
    10321 tgccgtctcg gccgcggacg ccctgatctc cctcgccttc gcgcagctca ccaggcccga
    10381 agtgatgatc ctcaacgccg cgctgctgtc cgttgtggac ggttacgtcc aggaagccga
    10441 gatggacgaa cgggacgacg tcgacatagc cgagtacctg ggcgtcgcgg cggcgaagca
    10501 ctcggcgctg acggcctgcg cgtgcgagct cggtgccctc gccgcgggcg ccgtcaggag
    10561 tcaagccgtc cacctcaggg agttcggcga cgacgtcggc ctcgcgcgca agcacgtgga
    10621 cgacgtgctg gccatctggg gcggcgcccc cgtcagcggc cggccgctct acgacgacct
    10681 cgcgcaccgc cgccgcacgc tgcccgtggt cgccgcgatc aacgccggca ccgacgtcta
    10741 cgcgaccgat gcggaacccc gcgagctggc tcttcgcgtc gagcgggcgg gcggtaggaa
    10801 gtggtgcgag cagcaggcgg aactgctgct cgcccgcgcc ctcaaccacc tgcgtcaggc
    10861 cgggccgagg gcgcgggcgg cggaagacct gtccggcctc gccagggaga tcacgaccgc
    10921 caggtttgca ccggctcgaa ccccagcacc cgccgtgcct tctcaatcga cagcagcgtc
    10981 tcgtgaggac cgaactccct cttgagcggc acgcccggat agaccttcgc caccagctcg
    11041 tcgttcggcg tcgtcatgca cgtgtcggcg ttggcgatga tgaagacgtc aaagcccgtg
    11101 gcgtcgtggg ccaacgcctt gcgcacggcc tgagcaccgt cccgtgcgtc gatgtacgac
    11161 cagaggttcc acttgcgcgc gagcgggtcg gcgtcgaacg ggaagcgctc gtagtcgtgc
    11221 ggctccatga cgttcgagaa ccgcagcccg atgatcttca tctccggctc ccaccggcag
    11281 aactgctgcg cgagcgtctc gtccacgagc ttgcccagcg agtacgacgt ctcaggccgc
    11341 cccgcgtact cctcgtcgat cgggatgtac ggcgggggag tgtcgaacgg cagccccagc
    11401 accgtctcgc tggacgccca cacgacgttg cgcacaccgg ccagccgtgc cgcggcgaac
    11461 acgttgtaag tgctggtcac gttgttgtgg aaggtacgcg cgttgggtgc gacacccggt
    11521 ccggggatcg ccgccaggtg caccacgggc gtccagaccg gcgtacctgt cgtcgatgcc
    11581 gctgatcgcc tccacgacct ggccgtagtc ggtcaggtcg acgcgcgtga agtcacaccc
    11641 ctgatcagcc gggggagcgg cctggtcgag gttgtggacc tcccagccgt gctccagcag
    11701 gtcggccacg acggcacgcc cgagcttccc gctgcctccg gtcaccgcga cacgttgagt
    11761 catgagtcag atgttgccac ccgatgacag cgctcgggcg caggacgagc ttcccccgtg
    11821 cgtgaccgga cgcgctcagc tcctgtgccc ggccggcgtc gaccagcggc aggctctccg
    11881 cgacgcgcac gacgagcttg ccgtccgcgg cgaggcgggc gtactcggcg agctcggcac
    11941 cgaacggacg actgccggcg gagaacgtga cgcccagctc ggcggcgcgg ggatcggcga
    12001 tcgtgatgat ccgatcggtg gacgtcgcgc agttcgatcg acacctccag gtcacccgcc
    12061 ccggcggcgt cgaacacggc gtcgacgccc tgcggtgctg tcgcacggac gcggtcggcg
    12121 aggccgccac cgtaggcgac ggggatcgcg ccgagagagc gcaggtggtc gtggttgccg
    12181 ggggaggcgg taccgatgac cgtggcgccg cgggccaccg cgagctgaac gccgacgaca
    12241 cccacgaccc ctgcggcccc gtgcaccagc agcgtctcgc cctctccgat cccgaggtcg
    12301 tcgaggacgc ggaccacgtc gccatgacgg cgcgctaccg gggccggtac gcctcgacga
    12361 gcaccgcgag atgccggccg gcgatctcca gcggcgcggt gctccgggag acctgcgccg
    12421 acagttcggc tccttcgagc aggttgatca cgctgtgcgc gaggtcgtgc gcgacgtcgg
    12481 cggcgaagcc cgaacgttcg agcttggcgc ggaccagcgc gcgccagttc tcgtaggcgt
    12541 tctcggcggc ctgctggatc tcgggttccc tgcccgcgct ctccagcgcc gcggtggtga
    12601 cggggcagcc gtccagccag tccgactcgc gcaggccttc ggcgagctca cgggtgcagg
    12661 cgaccagcgc cgctgccggg tcctcctccc gctcgaacgc ctcgcgcagg aactcggcga
    12721 actcccggtc gccgtggccg atggcctcga ccgcgagttc tcgcttgccg ccggggaaga
    12781 agtggtacac cgagcccagc gtggcctccg cctcctggga gatctgcttg aggcccgtcg
    12841 cctcgtaccc ctgccgctgg atcaggcgtg aggtcgcccg gacgatccgc tccctggtgc
    12901 cgatctcgtg ctgggtccgc atgacggcca gagtactgga tagagcgttc gttctagagc
    12961 tgctacggtc taattagaac gttctttcta gagggggtct catgaagtct gtgactgtga
    13021 tcgggatggg gccgatgggg caggccatgg ccggtgccta tctcgacaag gggtacgagg
    13081 tgaccgtctg gaaccgcacg ccggccaggg cggacgagct ggtggtgcgg ggtgcggcca
    13141 gggcgggatc ggtcgaggcg gcgctcaccg cctcggacct ggtggtgctg agcctgatcg
    13201 accacgacgc ggtggacgcc gtcctggcgc aggcgccgga gaccgcgctg gccggacggg
    13261 tgttcgtcaa cctcacctcc gacaccccgg acaggatgcg cgcgacggcc gcgtggctgg
    13321 ctgagcgtgg ggccgtccag ctcgcgggtg gtgtgcaggt gccaccgccc ggcatcggta
    13381 cgccggaggc gatgacgtac tacagcgggc ccgaggaggt gatcgagtcg cgccgggcgg
    13441 acctcgaggt gctgaccggg gtccactacc tcggtgcgga ccaggggctg gcgccgctgt
    13501 actaccagat cgggatcgac atgttctgga cggcgctggc cggctacctg cacggccagg
    13561 cggtcgcgga ggccaacggg atctcggcgg acgagttcct gccgcacgcg gtgaggaccc
    13621 tggacctccg ctacttcctg gagttctacg cgccgcgcat cacggcgggc caccacgagg
    13681 gggacgtcga ccggatctcc atgggcgtcg cgagcgtcga gcacgtggtg cgcaccgcgg
    13741 aggcggccgg cgtggacggc tcattgcccg cggcggtgct ggagctcttc cgccggggag
    13801 tcgcggccgg ccacgggcag cgcagcctca cgagcctcgt cgaggtgttg aaagcgtgat
    13861 tccggtgcct tttcgagata ttcctggcgg gttgtaaatc acgggaaatc gtccaggtgg
    13921 cgcattgatg gtttggttcc gatcggtacc gtgaacgtgt gggaggccgc cgtttccgag
    13981 tgctcgtcat cgttttggtg acgatgctga cctcggtttc gagcgcctgc gccgacgatt
    14041 ctccgctgcc gggcggcttt gtgtaccagt tgcagggcta tcccggcggg cgactggacg
    14101 agctggcagc cgcgccgttt cgcaccgccg tggtggatct ggcgcgcgac gccggctcgt
    14161 cctatttccg ggctgacgag atcggccggc tcaaggcgtc cggaaagcgg gtgctcgcct
    14221 acttcgagat cggctcgatc gaggagttcc ggcccgacta cgcggcgatc cgcgccgagc
    14281 ggctgctgct caacgagtgg ccgagctggc cgggcgagca cttcgtccga tattgggaac
    14341 ccggctggtg ggagctcgcg gtgcggccgc ggctggaccg tgcgctcgcc gccggcttcg
    14401 acggcgtcta cctcgacaca ccgctcgcgt acgaggagat cgacctcgcg ctcctgccgg
    14461 gaaccgaccg ggtggcactg gcggggcgga tgacggacct gatcgtgcgg atcagcgctc
    14521 acgtcaagcg gctgaacccg gccttcggtg tttacccgca gaattcgccg gagctgcgcg
    14581 agtaccccgg ctacctcgac gcgattgacg gcatcgggat ggaggagctt ttcttccgtg
    14641 ccaccgacga gccgtgcacc gcggacttct gcgccgcgaa cctcgcccag acgaggaagc
    14701 tgaaggaagc cgggaagacc gttttggcgg ttgactacgc gacgcgtgcg gagaacgtcg
    14761 ccgaagcgtg ccggcgttat cgcgaagaag gattcgaagg atatgtgacg gtgcgggcgc
    14821 tcgacacggt cgcggctccc tgccggtgaa tggcgtgcga acacaaggga ggagccggtc
    14881 gtgacaggcg aggaaacgaa attccgccaa gtgggcatca tcggaatggg gtacgtcggc
    14941 ctcacgctcg ccgcggcgat ggcccgccgc ggctacgagg tgcacggcgt ggacacccag
    15001 ccggcgttgc tggagacgct ctccaacggg cggccgcaca tcttcgaacc cggtgtcgag
    15061 gacgtgttcc aggagtgggt cggcagacgc atcttcctgt cgcacgacct gccggactcc
    15121 ggggtggacg cggcgatcat ctgcgtgtcc acgcccgtcg gcgagtctgg ccgcgagccc
    15181 tacctgctca acctcgccgc ggcggccgag cacatcggca agcggtgcgc accgggcacg
    15241 ctggtggtcg tgcgcagcac cgtgccggtc ggggcgacga ggtcggtggt gctgcccaag
    15301 ctggccgagg cgtggggatc ggcccggctg gtgatggcac ccgagcgcac gatccaggga
    15361 caggcgctgc gggagctggt cgaactgccg caggtcgtcg gcggtctcga cgacgagagc
    15421 ctgcggctgg ggctggagct cttcggcggg ctctccgcac agctcgtgcc ggtctcgacg
    15481 ctggagaccg ccgagctggt gaagctcgtc aacaactgcc acaccgacgt catctactcg
    15541 ttcggcaacg aggtcgcgcg gctgaccgaa cggctcgggc tcgacccgct cgaggtgatc
    15601 agggcgacca acgccgacta cccgcgtccc gacatctgca agcccggcta cgtcggcggc
    15661 ggctgcctgt cgaaggaccc gtacctgctg ttgtccgcgg ccgagcaggc gggctacgtg
    15721 ccgaggttga tcaagtcggc tcgcggcgtg aacgaggacc tgcccgtgca cgtcgcggaa
    15781 cgggtgatcg agatgatggg cgagccggag ggcaagcggt tgctcgtgct cggctgggcc
    15841 tacaagggct ggccgcccac cgacgacatg cgcggcacgc cgatcgcgtc gatgatgccg
    15901 gggttcaccg aggcgggtgt gcaggtgctc ggccacgacc cgctcgtgga cggcgacgtg
    15961 atcaggcgct acggcggcac accggtggac gtcgaggccg ggttcgcgag cgccgacgcc
    16021 gtgctggtga tcaccgatca ccccgagtac cggcggctcg acgtcggccg gttgctgccg
    16081 ggatcgggag tgcggctcgt ctacgactcg tggcgggtgc tcagcgaacg cgatgtgacc
    16141 gggcacggca tccggtacgc cgccctcggc tacgagccgg aggtggcgtg aatgaagaac
    16201 ctcgtgctgg gtggcgccgg gttcatcggc ctccacctca ccaggagact cctcgccgac
    16261 ggccacgagg tgacggtcgt cgacgacttc tcgcgcggcc gccgcgatcc cgagctcgaa
    16321 gcgctggacg tgccggtgat ctccgccgac ctcacggacc ccgcgtcgtt cgccgcgctg
    16381 ccacgcgact gcgacgacgt gtacctgctc gccgcggtgg tgggcgtgcg caacgtggaa
    16441 cgcgaccccg cacgcgtcgt ccggatcaac acgctcgcgg tgctcaacac cctggactgg
    16501 atcacgccgc ggcagcggct gttcttcgcc tccaccagcg agacctacgc gggcggcgtc
    16561 ggcaccgggc tcgtgccggt gcccaccccg gagaccgtgc cgctcgtggt cgaggacgtc
    16621 accgcgcccc ggttcgctta cggcgtcagc aaaatgctgg gcgaggcggc ggtgatccac
    16681 acgggcaggg ccaagggcgt gccggtcgtc gtcgggcgct tccacaacgt gtacggaccg
    16741 cgcatgggcg ccgaccacgt catcccggaa ctgtgcttgc gcgcgttgcg ccgcgaggac
    16801 ccgttcacgg tctacggtac cgaccagttc cgggcgttct gccacgtgga cgacgccgtc
    16861 gaggcggtgg tggggctgat gcgcaccgag aaggccgcgc accagatcgt ccacatcgga
    16921 gacgacacgg ccgagacgaa catcggcgag ctggccgagc tggtgctcaa gatcgcgggt
    16981 catgctccct ccgtgcaccg cgccgccgca ccgccgggat cggtcgcccg ccgctgcccg
    17041 gacctcacgt tgctgcgcgg cctgaccggc taccgcccgc gcgtcgccct cgacgagggc
    17101 gtccgccgga ccttcgactg gtaccgcgcc gaccagttct gagcccagcg cgaaagcacg
    17161 tccggggcga gcccggacgt gcttctcccg ttgtgcgtca cgagtgctgc cacagcgaac
    17221 ggaccgagtc ggccaggtcg tggtgcggtg accagcccag tgcccggtgg gcgcggctcg
    17281 tgtccgcggc gatccacgtg acggcgcccg accgcgactg aaccggagcg gtctcgcgca
    17341 ctctgccccg gaaccccgcc acctcggcca gcatcgccac cacctgccgc accgccacgg
    17401 cctgcccgct cccgacgttg agcaccggct cgcccagccc cggtgccagc gcggcgtcgg
    17461 cgatcgccga cgccacgtcg gtgacgtcga cgaagtcgcg gtaggaaccg agcgggccga
    17521 gtgtgatgtc gtccccctcc cgcatcgccg cccgtatcgc ctccgccgct cggccgagca
    17581 cggtgccggc gggcaggtcg gggccgatcg ggttgaagat ccgcaacgcc accgcgtcca
    17641 gccgtcccgc cgcgaccgcg tcccgcacca gcaacgtgct cgcgagcttc gtgatcccgt
    17701 acgcggacac cgggttcgcc gccgcgtcct ccgcgaccgc gctgccctcc cggacgcgtc
    17761 cgtactcggc ggccgacccg agcacgacga gccgggcacg cggcaccgcc tgcgggatcg
    17821 cgtcgagcag cgccgcggtc ggtgtcacgt tggcggtgac cagctcactc gtcgtaccgt
    17881 cgagcaaccc ggtgcagttg acgacgacgt ccggcctgac cgaccgcaac aggccgacga
    17941 gctcaccgct gctacttcgc accaggtcgt ggcgcaccca gccgtcctcg cccggcaccg
    18001 ttctggtgac ccggacgacc cgcgcgccac gcgcgtggag ttcttcgccc gccgcgcggc
    18061 cgaggtagcc ggacgcgccg aacagcagca ctgtcacgac gtcacgtcca tggcgttgtg
    18121 gcgaacggat ccgggcagca gcgccggccg cagctgctcg aagttccggt tggcctcgtc
    18181 gtagtcgtcg ggccggccga tgtcgagcca gtagccgccg aactcgtagg ctgccggttc
    18241 ctcgccgcgc gccagcaggt cgagcacgag ctcgtccagt ccgaacggga cgttgcgcgg
    18301 gtacggggtg agcgtcttgc gggtcatcgc gtacacaccc atgctcacgc cgtaggacag
    18361 ctcgggcttc tcgacgaagc tgacgatgcg tccctcctca gtggacagcg tgccgaagtc
    18421 gatcttaacc ttccgttggt aggtagcgac tgtcagcgga gcaccgcacg tgatgtggtg
    18481 gcccagcagt gcctcgtagt cgaggtcggt gagcacatcg ccgttcatca cgaggaagtg
    18541 ctccggcagg aggtcgacga tgttgagcaa cggcccgatg gtggacagcg gcatcttctc
    18601 ctccgcgtag tccactctga tgttccagcg cgacccgtcg ccgacgaacg cgcggatcag
    18661 cgaaccgagg tggccgatcg cgagcgtcac gcggtcgaag tgccgcctgc cgagctgctg
    18721 caggatgatg tcgagaatcg cgtattcctc gccgatcggc acgagcggct tcggcaaagc
    18781 cgtggtgtac ggccgaagcc gcactcctct gcctccggcg agtatcaccg catgcatggg
    18841 aatcacttcc tcatcggtag tggcggacct gtccgacgct cccgcggagc gccacgagca
    18901 agaagatcga caacgcggtg caggtgatca ggaaggccgg cacgggatcg gcgccgagcg
    18961 cgaccgccgt cacgtcaccg agcagggcgg cggacacgat cagcggcgcc ggcagcgggc
    19021 cggaggtccg gacgaggacg aagcccagga agaacgcacc gccgagcagc acgtgcccgt
    19081 cgatcagcag ggcacccggc gacgtgagca cgccggagac gcgcagtgcc acgagcagga
    19141 cgagagcggc cgcgccgagt gccgtcaggc agaagcccag ttcccgcagc aacccgcgcc
    19201 agatcgcctg gtggaagtcg gccggcagcg cgcaccggcg cagctcctgc gtcgccagtt
    19261 cgaagaaccg gtgggcgcgc cactcgacca cgcccatccc cagcaccaac ggcgccgccg
    19321 cgaccgcgag gtcgagtgcg ctgagcacgt agcgagagtc cgtgtacagc aacaggatcg
    19381 cgcacagcgc cgcgtacacg ctgctgggca acgcggtacc cagcagcgtc aacgcccggg
    19441 gcgggcgcac accaccggag tcgcgggcgg cacgccctgc ccgccacgcg ccaccgacgg
    19501 cgagcagcac cgtcacacca ccgagcacca acgcgatccc gacgacctcc gacaccagga
    19561 acagcacccc gccggcaccg gcgggcagca ccgccaccgc gagccgaacc tcctcgcggt
    19621 ggaacaggag caccccgatc gcgaactgca gaccggccaa cgccagcacg aacaacgcgg
    19681 accaccagcc cagcaccgcg gccgccgtcg tcgccgcgac agccgtcccc gcggcaccga
    19741 gccaccgcaa cgacctggcc gcggtggccg cagccccgcc gctcagcaac cggtgcgcga
    19801 cggcgctcgc acccgagccc cacacccagc tcacggcggt ggcgacgacc atcgcccgca
    19861 cggcggccgg accgcccagc accgcggcca cggcgggaaa cacggtcgtc ggcacgaggt
    19921 acagcggtcc gcgcacggcg tgcagccacg tggtgccagg ggagtggtcc tcgacggcga
    19981 cgctcccacg cggcaaccgt tcgaacacct cctgcccgag cgcgaacacg tcggcgcgcc
    20041 cgtagcggtc caccgcgacc tggtcggtga tgccctggct ttccagcaag gcagccacct
    20101 gcagctcgtc caccgggtcg ggcagcaggc tcgctacgcg ctccaccagc tcgtcgagga
    20161 tcacggcgcg acccccgtcg tagtgagctc ggcgtacctc gcgcggtagc tgtcgttcca
    20221 ccgctgcacg gtgaagcgct cgatcacccg ctggcgcgcg agtccgccca gcttgcgccg
    20281 caacacgttg tcggtgagca gccgcacgca cgcccgtgcg accgcctcgt gatcacgcgg
    20341 cggtaccacg agacccgcgt cggcgaccgc ctcgctgacc ccgccgacgt ccgtgcacac
    20401 cggcggtctg ccggtggaca tcgcttccac gacggtgaac ggaaagcctt ccgacacact
    20461 ggtcaacgcg acgaggtggc ccgcgtggta ggcgtcgacc tggctcggca ccagtccctc
    20521 gaacaccgcg ctgccggcga gcccgagctg gtcgacgagc cgcacgcagc tcgcgtggta
    20581 gtccttgttg gcctcgggca ccgggccgaa gacgcgcagg cgcgcttccg gcagcgcgcg
    20641 gcggacctcg ccgaacgccc tgatcaacgt gtgcaggtcc ttgagcgggt cgatccgccc
    20701 gacgaacacg atcgtcggca cgtcgggttc tcccggcgcc accgggaact cggcggggtc
    20761 gatgccgttg tacatcgtcc acatgcgacc ggagtcggcc ccgctgtgca gctgccaccg
    20821 ccggttgtag tcggagtgcg gcgtgagcat gtcgcaggcg cggtaggcgg cgcccgcgag
    20881 cgcccggtgg aagctcagca gcacgacctt cgccggcagg gcgagcgact cgccgaccgc
    20941 gcccagatag cgctcacgca gatacacgcc gtgctcggac atcagcaacg gcgtaccgtg
    21001 cgccc
//
