LOCUS       NZ_QGHB01000001        22043 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Lentzea atacamensis strain DSM 45480 Ga0215650_101, whole genome
            shotgun sequence.
ACCESSION   NZ_QGHB01000001
VERSION     NZ_QGHB01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea atacamensis
  ORGANISM  Lentzea atacamensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 1817104)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1817104)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Expected Final Version            :: No
            Genome Coverage                   :: 90.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003148865.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:35:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,333
            CDSs (total)                      :: 9,254
            Genes (coding)                    :: 9,110
            CDSs (with protein)               :: 9,110
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 6 (5S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 32 of 144
            Pseudo Genes (incomplete)         :: 121 of 144
            Pseudo Genes (internal stop)      :: 2 of 144
            Pseudo Genes (multiple problems)  :: 11 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:50:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1474899
            Orig. end                         :: 1496942
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QGHB01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22043
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="1"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22043
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22043
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12043](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12043)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            complement(444..1499)
                     /locus_tag="C8D88_RS07695"
                     /old_locus_tag="C8D88_1011557"
     CDS             complement(444..1499)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229156.1"
                     /locus_tag="C8D88_RS07695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011557"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_233439201.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.1e-28,
                     bitscore: 96.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPVEAGVAKVVLDLAEAQRAAGWEVHVVCPPHGWLPTRIPTHP
                     WHATRSPGPASLLETLRLRKVLRDLRPDVIHLHSSKAGLTGRLAVRGRTTTIFQPHLWS
                     FRLADGLLRRMCVRWEAFASRWTHQLVCVSDDELATGRAAGVTTPAEVVCNGIDTTRLR
                     PADRSAARRRLGLPERPTAVCVGRLAPQKGQDLLLAAWPDVLADVPHAQLVLVGDGPMR
                     TAWQNGQESVLWWGHSDNVEDFYAAADVVVLPSRAEGMALVPLEAMACGRSVVAFDVDG
                     VRQSLGSAGAVVPGEDTAALGQALATRLADPSLAHREGHAGRRRAEMLFDRARMTDQII
                     TLVEKLEGDAR"
     gene            complement(1511..2923)
                     /locus_tag="C8D88_RS07700"
                     /old_locus_tag="C8D88_1011558"
     CDS             complement(1511..2923)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229155.1"
                     /locus_tag="C8D88_RS07700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011558"
                     /product="oligosaccharide flippase family protein"
                     /protein_id="WP_233439202.1"
                     /sec_met_domain="Polysacc_synt (E-value: 4.4e-20, bitscore:
                     69.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNRVGERAVRGSLWLFAVNVVSKGCQVAVTLVLAALLTEDGLGA
                     VSLVVSLVNIGQVVQSAGVYDVISRTNLDPGRLAGTVLTLSASGGLVLTVVLLLAAEPL
                     AAALGAPATLIRIAALSLPFTAIGGVQMALMHRDLDFRRRMLPDAGGMVLGAAVTIVLA
                     ALGFGPLAMAVGLLCTAVAQPVLAVVAGARVRPRWDRAAAGEALRWTAVVGPGAVVATL
                     LINVDYLTIGHVLGPSAVGVYSLAFRIAWMPYILVAVVLGGVMFPVCAELVRSGRTGDV
                     PGAVLRFTKATLMITGGFFVVIALLADQVVLFGERWAPAAPVLVALCAYGLGLGLLHTW
                     YQVIRAAGHARWYLALEVTHLVALLSALAVTTRHGVLAVAIAQAVIVWLLVPLTWWVLV
                     RHGLAFPPAELGRTVAGLLTACASCALVARLLPDTNGIAGALLAGLVLFGVYAAISLPL
                     NREAVRELRGTL"
     gene            complement(2920..4158)
                     /locus_tag="C8D88_RS07705"
                     /old_locus_tag="C8D88_1011559"
     CDS             complement(2920..4158)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004559956.1"
                     /locus_tag="C8D88_RS07705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011559"
                     /product="glycosyltransferase family 87 protein"
                     /protein_id="WP_211337147.1"
                     /transl_table=11
                     /translation="MITTTKPDTRTLITIAVAVIGALSAARALRPSWEVPAPTGENLAE
                     ERLQDFRDALYFPIREFLAGGNPYDPAAMFEHWPVRQNFNLYQPYHLVLHLPFALPEYR
                     IGAIAFTLASLVLLGVLGLLAARRAKLPLVLGTVVIGALLVTSQVGKAQLYVGQVNPLI
                     AVGAAAALLARSSHPRVAALGLAVAWLKPQFGLPLAILLFARGSRRVALGGTVIAALAS
                     LPVVGLLVYRGGGVGPFLDVISANLAHASGTSYGAVDSVTAQRVDLPAVFFRVTDWLPP
                     AAELTALVGVLAATAYLARKLDGGDSDSRSVADLITAVGAVVAVVHQPGDVLIAVPAMA
                     AVAVVCWRRRKERDWRITGFAVVALLVPFAHLYFVNSAIIGLFGRRVDVTVDGVAIVVA
                     WVLLVVVAARKRA"
     gene            complement(4155..5024)
                     /locus_tag="C8D88_RS07710"
                     /old_locus_tag="C8D88_1011560"
     CDS             complement(4155..5024)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229153.1"
                     /locus_tag="C8D88_RS07710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011560"
                     /product="hypothetical protein"
                     /protein_id="WP_109632189.1"
                     /transl_table=11
                     /translation="MNKRTLLEATAVALVVAVLVLAVTSLRGEQYESRIAVLAVPVTQT
                     DSAAQYGEVASLAMPAIVQMVHSPTVLEAAARAASTTPREIADGVGVELVPASGLARLS
                     VRAGSDEQAGAAVTAVAKAVADANLLAPAGRLRVLDERPETTRVAPDWKLAAGLALAAA
                     LAAGIATAALRALRRPRTGEAAVRAAVATAGLRHPVALVREDDPEMLDRLTALCVAAAR
                     PVRVIPADHGLTAQAESLAESLPDKAAEPGEGTAVIAVADGGGEPVDLAAALAVLPASA
                     VLVAVVLT"
     gene            complement(5021..6082)
                     /locus_tag="C8D88_RS07715"
                     /old_locus_tag="C8D88_1011561"
     CDS             complement(5021..6082)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640643.1"
                     /locus_tag="C8D88_RS07715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011561"
                     /product="glycosyltransferase"
                     /protein_id="WP_109632191.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 7.8e-32,
                     bitscore: 107.1, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLHVISEMGAGGAEAVVAGMVRAGGDFGWESGVASGGGHRAEA
                     LRAQGFSTFDVPVPRRRVSGVLRAVSAVRSAVRSFGPDVVLAHNVSASLVARMAAGGRP
                     VATVFHGVSESDLGGAARILRRTSRAVVAVAEASADRLRALGVDVEVIPNAVFAEPPRV
                     DRASIRGVLGIGPDVPVALCPARLEPQKRHDVLLEAWAMVAGAILLLAGDGSLRADLER
                     RAEELGVGDRVRFLGTRCDVPDLLEATDVVVLTSDWEGMPIAVLESLAAGRPVVASDVD
                     GVREALSGGGGVLVPRRSPSTTATALASFLFDARACAAAGAAGRAAVERDHDPHTFMKS
                     YDELLRTIGGEQR"
     gene            complement(6057..7220)
                     /locus_tag="C8D88_RS07720"
                     /old_locus_tag="C8D88_1011562"
     CDS             complement(6057..7220)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103312.1"
                     /locus_tag="C8D88_RS07720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011562"
                     /product="O-antigen ligase"
                     /protein_id="WP_109632193.1"
                     /sec_met_domain="Wzy_C (E-value: 1.5e-15, bitscore: 54.4,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLLRVLACATVLLAPLEGYLQEVHPHLAKVVPALLIVSWVAQR
                     VRERRLPAPHPLHALLALFAVVLLASSAVHAADPFTAAYTQRFLPFLVITAVLADVAAR
                     EVPVRAVLAAAVGGAVSAAVGALYSLVVDGEARATGPLEDPNDLAYFLVVALPLLIALP
                     ARRFLLPVGAILAAGAAATFSRGGGLALAFAAVWLVARRGVSMRAVTATVSGLAVIGLG
                     AVVFAGPVLERALAEKTYIAATNVDTRELRWQAAARMLADNPVLGVGPGGFRSEYPAAS
                     RNAEIDEQSPVAHNIYLEIGAELGLPGLACFLGAVALAFVATERVLRARADRSMLAVQA
                     SLIAALVAATFLSEQYYLPIWSLVAVAIAADLRREESERDACAARHQ"
     gene            complement(7217..8158)
                     /locus_tag="C8D88_RS07725"
                     /old_locus_tag="C8D88_1011563"
     CDS             complement(7217..8158)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103311.1"
                     /locus_tag="C8D88_RS07725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011563"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_109632194.1"
                     /transl_table=11
                     /translation="MRPASVSLDLDNLWAYLKTHGNPDWESRPSFLATAVPRLLDVFGE
                     HRLTTTVFVVGADAERDDGAQAVRDIVAAGHEVANHSWGHEPWLHRYSRPELEAELVKA
                     EDAITAAGAPRPAGFRGPGYSVTPALLEILAARGYRYDASTLPTWIGPLARAYHNRTAR
                     DRAEGAGDLFGGFDKVLAPNTPFRWHGTGLVELPVTTMPLLRVPIHGAYLLQLHQISPR
                     LARGYFRAALRLCLLTGTAPSLLLHPTDVLSGAEAPGMEFFPGMAVPGTEKAALLGWVL
                     SSLRENFDVVGTGAHVDRLSELLRERRTELCG"
     gene            complement(8155..8979)
                     /locus_tag="C8D88_RS07730"
                     /old_locus_tag="C8D88_1011564"
     CDS             complement(8155..8979)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004562867.1"
                     /locus_tag="C8D88_RS07730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011564"
                     /product="hypothetical protein"
                     /protein_id="WP_109632196.1"
                     /transl_table=11
                     /translation="MSGYLELVFSTALYGLGIVAQTVAAQRADVRPGTGLGLLARLAKD
                     RLYLFGFAGQVGGFGFAFLARAELPLYLVQAGSSCAVGLATAFGLLVLKWRVRPLEIAV
                     LVMMAIGLVLLVTASESSVAKDIPTVPGLVLLGLPLLVIVFCSRAAQGSNSVIVSVLAG
                     TAFAVVAIIGRSVADESPADMLLNPLTWLMIVAALVGQSCLAVALQRGTATSSVAATDA
                     TTVVLTSVIGIGMLGDRITPGWEWAVGFGMTLVVAGVLVLGSPNRTTAEVAG"
     gene            complement(9123..10004)
                     /gene="pqqB"
                     /locus_tag="C8D88_RS07735"
                     /old_locus_tag="C8D88_1011565"
     CDS             complement(9123..10004)
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631257.1"
                     /locus_tag="C8D88_RS07735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011565"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_109632199.1"
                     /transl_table=11
                     /translation="MKAVLLGTTAGGGFPQWNCACALCVRARSGELPSRSQDCLAISGN
                     GTDWWLVNSSPDIRTQVAACSPLNPGPGPRDTPIRGALFTDAELDHTLGLLTLRGGAGL
                     TVWAPGPVLHALRDQFDLRTVIDGYAPVAWRQVEADQPLDLGGLLVSAIPISGKRPKYA
                     RSSTVDGHWVVAYRFEDPISGGVLVYAPCLASWPAGFDDVVAEADCLLLDGTFYAASEM
                     GSATGSSSGQAAMGHLPITHSLPELRRFPSVRRIYTHLNNTNPVLDPESPEAAKLREAG
                     VEVPPDGTVIEL"
     gene            complement(10001..11080)
                     /gene="pqqE"
                     /locus_tag="C8D88_RS07740"
                     /old_locus_tag="C8D88_1011566"
     CDS             complement(10001..11080)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098206.1"
                     /locus_tag="C8D88_RS07740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011566"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_109632201.1"
                     /sec_met_domain="PTHR43273 (E-value: 7.2e-34, bitscore:
                     114.1, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.9e-24, bitscore: 83.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 7.4e-06, bitscore: 23.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 7.2e-13, bitscore: 45.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.5e-13, bitscore:
                     45.7, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEAPFGLLAELTHRCPLQCGYCSNPVELVRRNAELDTESWRRVF
                     DQARSLGALQIHLSGGEPLLRPDLPELVAHANSLGCYVNLVTSGVGLSRERLRELASRG
                     VDHVQLSLQDATKAGNDRIAGIKAFDRKVEAAAYIREEGLPLTVNTVLHRQNLDNIAGI
                     IAMAEEMGAERLELANTQYYGWALRNRAVLLPTREQLAVADPIVAAAQERLRGRMEIVY
                     VIADYHEAHPKPCMYGWGARQLTVAPNGDVLPCPAATVISSLQIENVRDSSLHDIWHNS
                     ASFNAFRGYEWMKDPCRSCPRKEIDFGGCRCQAFQLTGDAANTDPVCSLSPDRSTVDLI
                     LATEMAPSEVPAMAMRKMS"
     gene            complement(11073..11351)
                     /gene="pqqD"
                     /locus_tag="C8D88_RS07745"
                     /old_locus_tag="C8D88_1011567"
     CDS             complement(11073..11351)
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098207.1"
                     /locus_tag="C8D88_RS07745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011567"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_233439203.1"
                     /sec_met_domain="PqqD_RRE (E-value: 1e-19, bitscore: 66.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.9e-11, bitscore: 40.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSVVALDAVPRIRRGVKCTYDQIREAHVVLFPEGVLVLNETAAS
                     VVSLCDGVRSVGDIALALGDVYAGVQPEDIAELVARLVERRVVDVDG"
     aSDomain        complement(11085..11342)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C8D88_RS07745_PqqD_RRE.1"
                     /evalue="1.50E-21"
                     /identifier="RREFam006.1"
                     /label="C8D88_RS07745"
                     /locus_tag="C8D88_RS07745"
                     /protein_end="89"
                     /protein_start="3"
                     /score="66.9"
                     /tool="antismash"
                     /translation="VVALDAVPRIRRGVKCTYDQIREAHVVLFPEGVLVLNETAASVVS
                     LCDGVRSVGDIALALGDVYAGVQPEDIAELVARLVERRVVD"
     gene            complement(11348..12043)
                     /gene="pqqC"
                     /locus_tag="C8D88_RS07750"
                     /old_locus_tag="C8D88_1011568"
     CDS             complement(11348..12043)
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033798.1"
                     /locus_tag="C8D88_RS07750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011568"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_109632203.1"
                     /sec_met_domain="TIGR02111 (E-value: 3.7e-84, bitscore:
                     278.6, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVPPEEFVAELRALAPRYWDSHPFHLRMHAGQLSKHELQAWAA
                     NRWYYQRCIAQKDAAILSNCPIPDIRRQWRERIIWHDGTQPGEGGAENWIRLAEAVGLT
                     REEVLDERHVLPGTRFAVDAYVNFARTKPWVEAIASGLTEMFSGALMRKRLAALREQYP
                     WIAEEGFAYFTNRIQAVAGEGQATLDIVVEHSRTRAQQEAAIAALSFKCDVLRAVLDTV
                     DYYSGKGKP"
     gene            complement(12137..12259)
                     /gene="pqqA"
                     /locus_tag="C8D88_RS07755"
                     /old_locus_tag="C8D88_1011569"
     CDS             complement(12137..12259)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670613.1"
                     /locus_tag="C8D88_RS07755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011569"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_109632205.1"
                     /transl_table=11
                     /translation="MNVVVNTAEQKLPEVKREWVKPDFRDFETPMEVTAYAARS"
     gene            12528..13523
                     /locus_tag="C8D88_RS07760"
                     /old_locus_tag="C8D88_1011570"
     CDS             12528..13523
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631253.1"
                     /locus_tag="C8D88_RS07760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011570"
                     /product="sorbosone dehydrogenase family protein"
                     /protein_id="WP_109632207.1"
                     /transl_table=11
                     /translation="MGARRSAYAGVLALAVGLSSSPLASAAESGEVGTMAVKTIATGLK
                     QAWSIDFLPDGTGIFTQKDAKTVSTITKDGKVTKVGDIPGVSVTKEAGLLGIAVSPTYA
                     ADKTLFLYYTTGSDNRIATWKIGDTATKPIVTGIPRGSQFHHGGRIKFGPDGFLYAGTG
                     DGQNGSNAQNKNSLGGKVLRMTKDGKPAPGNPFNSLVYSYGHRNVQGLTWLGSQLYVSD
                     IGASKVDELNKIDAGKNYGWPTCEGSCGTAGMTNPVKQWPTSQATPSGLTTYKGHFYMA
                     SLKGGTFKLTPNGAGGKIYTNLGRTRDEVAGPDGSLWVITPGGIHIADGN"
     gene            13704..14597
                     /locus_tag="C8D88_RS07765"
                     /old_locus_tag="C8D88_1011571"
     CDS             13704..14597
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098210.1"
                     /locus_tag="C8D88_RS07765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011571"
                     /product="sorbosone dehydrogenase family protein"
                     /protein_id="WP_109632209.1"
                     /transl_table=11
                     /translation="MRARRIAVAAACRGRSLCVIPASAQDGPPVLAERTIATKLDIPRD
                     IEFLPDGSGIFTERDTRKIKKVTGTTVTELDTVEQAQTTGGEGGLLGLAVSKTFATDNS
                     VFIYYSTASDNRVAKLRLGGTPQVIVSGIPKNRYHNGGGLEFGPDGFLRATTGDGQNAS
                     TAQNWNSSGGKVLRFATAGRPAAGNPRAGSIVYSIGHCNTAGMTNPVKTWPTSQAGPAG
                     IGYYKNALYVGAVTGSRVWKIPVNGTTLGTPQAVFTSYGRVRAVAPAPDGTLWLGTSNQ
                     DGQPDANDDRIVSTDG"
     gene            complement(14606..15754)
                     /locus_tag="C8D88_RS07770"
                     /old_locus_tag="C8D88_1011572"
     CDS             complement(14606..15754)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098211.1"
                     /locus_tag="C8D88_RS07770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011572"
                     /product="polysaccharide deacetylase"
                     /protein_id="WP_233439204.1"
                     /transl_table=11
                     /translation="MTTGLALALALVLVMTLGPTKDQQSQADAGPLPMAPRLPAPKDAG
                     PTPAVPAPSPEQLQQQPWMHKLAPGEKPPQFVLFSFDGAVSKQHWDKVLPIAREKKAHV
                     TGLLSGVYMLADQDKMQYQPPAGLKRGVSDISFGGSKQDIAARIGYLNQVIDEGHEIGT
                     HYNGHFCSGGTQPSVDKWDSKAWNEELAQFKQIVDRARAAGFKLADGAVRGGRTPCLEG
                     NWDHAFPAMAANGLAYDTSKVALGVQWPSIQNGLYEFPMPEVRVPALGRQVVMMDFNLW
                     YALNGARDEPHRATEFAQIVFDTYKSVHQAALNGNRAPLVIGNHFNEWNGSAFSNAMEQ
                     FLAYVCDKPETVCATYTEVIQWMQLQDPAVLDQLRRMPAARN"
     gene            complement(15812..16516)
                     /locus_tag="C8D88_RS07775"
                     /old_locus_tag="C8D88_1011573"
     CDS             complement(15812..16516)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098212.1"
                     /locus_tag="C8D88_RS07775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011573"
                     /product="class F sortase"
                     /protein_id="WP_211337148.1"
                     /transl_table=11
                     /translation="MAQAVSPKAFLTGALVAGVAATSVLVTASGTEVLKGHAVADEIPV
                     VGPGPVADSLSTGRGADLTGLVGGANTANAKPAEPTQPQPAPPKAGPGSVRLPSGGTAT
                     LVRREVKDGVLPVPDGIGEATWWGAELAGQEGATVLAGHVDWKGARGPFAELWQAQNGR
                     EVVIADSAGKEFKFRINQIETVRKEELPARAVEFFGPRGPRRLVLVTCGGTWIGGQQGY
                     EANRVVIAEPVA"
     gene            complement(16501..17889)
                     /locus_tag="C8D88_RS07780"
                     /old_locus_tag="C8D88_1011574"
     CDS             complement(16501..17889)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098213.1"
                     /locus_tag="C8D88_RS07780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011574"
                     /product="collagen binding domain-containing protein"
                     /protein_id="WP_109632213.1"
                     /transl_table=11
                     /translation="MGWKRLAAVAVVSGLALLTAPTTATAVGVKGIGHNASGLQPNATP
                     GSEWHGSYVWQNKHVWCVQYALPAPDSNVGYKEGDELLTKAGKKLPSDIAANISYLLLR
                     YSTTKSAEEAAALAHLLHTWTSPVDGNVNLGATDPKYLAYDSAFYASKLPPAVMDTVAR
                     LKADAEANRGPWTLSATAPKEPLIIGTESSWTVSLVKANGQGVPSAPIDFTLTDATLVD
                     GSVGGKATTGADGSPATIKILPTGPKPSIAANADSPADKPVVHQPISTDNMQRMVTTGG
                     EKKLSANATGQAKTAPGKVKITKIDSETKKAIAGVALRVTSKDQTKPALKQDDTELVGT
                     DGKPLVLQTGADGTVEVPDLRTPQEICLVEVAAPKGYEEFFDPKAPPASCGTLAAGQTL
                     ALELVNKPNKPVVPSTIPAGQDGKTPVATASFETQLRPGVMLAVGGLVLLGAALAGFLV
                     WRRQ"
     misc_feature    18002..18019
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.84"
                     /tool="antismash"
     gene            18208..19008
                     /locus_tag="C8D88_RS07785"
                     /old_locus_tag="C8D88_1011575"
     CDS             18208..19008
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005155843.1"
                     /locus_tag="C8D88_RS07785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011575"
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="WP_109632215.1"
                     /transl_table=11
                     /translation="MRSSSNPAFRNLPTGGGYGGYAGFGQPEAGYQQAPPPLTSERPMT
                     IDDVVTKTGITLAVVAATAVVTYVMQWWNLLFPAAIIGLVLALIIMFKRMPSPPLVIAY
                     AAVEGIFLGAFSGIIGAMIDRWTGPGQGVVVIGQAIIGTIGVFAGMLIVYKTGAIRVTP
                     KFTKWITGAIIGVAVLMLFNLIMSFFTDGGLGLRNGGALAIIFSLVCIGLAAFSFLIDF
                     DAADQAIRAGVPAKFAWQIAFGLTVTLVWLYTEILRLLSYFNSD"
     gene            19073..19402
                     /locus_tag="C8D88_RS07790"
                     /old_locus_tag="C8D88_1011576"
     CDS             19073..19402
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D88_RS07790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D88_1011576"
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="WP_109632217.1"
                     /transl_table=11
                     /translation="MSKRFGEAMRLMRRRNGQDCETGFAMLKPHAAEHLDELIEEFHRE
                     EDDQGLRAWLLELIGEAGDPRALPLFVAHLDDERFGDWAIWGLEKLDTKEARTALYRHR
                     SNKHT"
     gene            19412..19822
                     /locus_tag="C8D88_RS07795"
                     /old_locus_tag="C8D88_1011577"
     CDS             19412..19822
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336503.1"
                     /locus_tag="C8D88_RS07795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011577"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_211337149.1"
                     /transl_table=11
                     /translation="MDHAYRLEMKPPAVDDYLRLRKESGLSARTVEEAENGINGAWASA
                     HVVHVESGETVGMGRVLSDGGWYFHIIDMAVLPHHQRKGIGDAIMTALLDRIGEHAPNA
                     YVNLLADPPGRRLYERHGFTESAPASVGMRRV"
     gene            complement(19819..20028)
                     /locus_tag="C8D88_RS07800"
                     /old_locus_tag="C8D88_1011578"
     CDS             complement(19819..20028)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8D88_RS07800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8D88_1011578"
                     /product="hypothetical protein"
                     /protein_id="WP_109632219.1"
                     /transl_table=11
                     /translation="MPYVWWQSEYDLQCHAFSLDQANGSRSFYEAVCEHSVPDERVSRA
                     QAGALCTTCLIKVGTQLPDVRWRA"
     gene            complement(20190..21410)
                     /locus_tag="C8D88_RS07805"
                     /old_locus_tag="C8D88_1011579"
     CDS             complement(20190..21410)
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005466189.1"
                     /locus_tag="C8D88_RS07805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8D88_1011579"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_109633212.1"
                     /transl_table=11
                     /translation="MPEAVIVSAARSPIGRAGKGSLKDVRPDDLAAQMVRAALDKVPQL
                     DPAQIDDLMLGCGLPGGEQGFNMARVVAVLLGQDSLPGTTVTRYCASSLQTTRMALHAI
                     KAGEGDVFISAGVETVSRFAKGSSDSWPDTHNPLFADAEARTVSVAQSGADEWVDPRSL
                     GVVPDIYIPMGQTAENLALLKGVSRQEMDEFGVRSQNLAEKAIADGFWAREITPVTLPD
                     GTVVSADDGPRAGVTYEAVSSLKPVFRPDGRINAGNCCPLNDGAAALVIMSDTKARELG
                     ITPLARIVSTGVSGLSPEIMGLGPVEASKRALALAGLSISDIDLVEINEAFAAQVIPSY
                     QDLGIDLDRLNVNGGAIAVGHPFGMTGARITTTLINSLQFHDKQFGLETMCVGGGQGMA
                     MVIERLS"
ORIGIN
        1 cgcgggtgcc ggcaccaccg tgcggtccac gcggcgcgcg acaagggcgt cggcggcgag
       61 cacggccatc gcgtacgtcg acggcctcgg tgcccgtgcg gcaccgcgga accacggctc
      121 gcccacgtcg tccggcacac cgtggtaggt gtgcacgacc gggatgtcgc cgagcccggc
      181 acacacgagc ccgctgcggc ggtcctgcgc gtgcacgacg tccggccgcc acgcccgcag
      241 tgccgcgcgt gcctgacggc tggcgcgcag atcacccttg ctcggcaccg agatctcctc
      301 gtgctcgacc aggtgcgcgt cgcgcgcggg aaccgggccg aacaccttga cctcggcctc
      361 gccggacgcc tgcagtgcgg cagcgaggcg gacggtgacg tcgaccgggc caccccggtc
      421 ctgcgtcagc aggtacgcga ccctcatcgg gcgtctcctt cgagtttttc cacgagcgtg
      481 atgatctggt cggtcatccg ggcgcggtcg aacaacatct cggcgcgtcg tcgtccggcg
      541 tggccttccc ggtgtgcgag tgacgggtca gcgagccggg tggcgagcgc ctgcccgagt
      601 gcggcggtgt cttctcctgg cacgaccgcc ccggccgatc cgaggctctg ccgcaccccg
      661 tccacgtcga acgcgacgac ggaccgcccg caggccatcg cttccagcgg caccagcgcc
      721 atgccctcgg cgcgtgacgg cagcacgacg acatccgcag ccgcgtagaa gtcctcgacg
      781 ttgtcgctgt gaccccacca caggacggac tcctggccgt tctgccaggc agtcctcatc
      841 ggaccgtcgc cgaccagcac gagttgggcg tgcgggacgt cggcgagcac gtccggccag
      901 gcggcgagca ggaggtcctg gcccttctgc ggcgccagcc ggccgacgca cacggcggtc
      961 gggcgctccg gcaacccgag ccgccgtcgt gccgcgctcc ggtctgccgg ccgcagccgc
     1021 gtggtgtcga tgccgttgca cacgacctcg gccggtgtcg tcacgccggc cgcgcggccg
     1081 gtcgcgagct cgtcgtcgct cacgcacacc agctggtgcg tccaccggga agcgaacgcc
     1141 tcccagcgca cgcacatcct ccgcagcagt ccgtccgcga gccggaacga ccacaggtgc
     1201 ggctggaaga tcgtcgtggt ccggccgcgc accgccaggc gcccggtcag ccccgccttc
     1261 gagctgtgca ggtggatcac gtcaggacgc aggtcgcgga gcactttgcg cagccgcagc
     1321 gtttcgagca gtgaggccgg tcctggggag cgggtcgcgt gccacggatg cgtggggatc
     1381 cgggtgggga gccagccgtg cggagggcac accacgtgca cctcccagcc tgccgcccgt
     1441 tgcgcctccg cgagatcgag cacgaccttc gcgacgcccg cttcgaccgg ttgcgtcacg
     1501 tgcacgacct tcacagggtt cctcgcagtt cgcggacggc ttcacggttg agcggcaacg
     1561 agatcgccgc gtagacgccg aacagcacca gtccggcgag cagcgcgccg gcgatcccgt
     1621 tcgtgtccgg cagcagccgg gcgacgagcg cgcagctcgc gcaggccgtg agcagcccgg
     1681 cgacggtgcg gcccagttcg gccggcggga acgcgaggcc gtgccgcacc agcacccacc
     1741 aggtgagggg cacgagcagc cagacgatga cggcctgggc gatcgccacg gccagcacgc
     1801 cgtgccgtgt ggtgactgcc aaggcactca gcagggccac cagatgcgtc acttcgagcg
     1861 cgaggtacca ccgcgcgtgt cccgctgccc ggatcacctg gtaccaggtg tgcagcaggc
     1921 cgaggccgag tccgtaggcg cacaacgcga ccagcaccgg tgccgcggga gcccagcgtt
     1981 caccgaacag cacgacctgg tcggcgagca gagcgatgac cacgaagaag ccgccggtga
     2041 tcatcagtgt ggccttggtg aaccgcagca cggcgccggg cacgtcaccg gtccgtccac
     2101 ttcggaccag ctcggcgcac accgggaaca tcacgccgcc cagcacgacg gccacgagga
     2161 tgtacggcat ccaggcgatc cggaaggcga gcgagtacac gccgacggcc gacggcccga
     2221 gcacgtgccc gatcgtcagg tagtccacgt tgatcagcaa cgtggcgacg acggcgccag
     2281 ggccgacgac agccgtccag cgcaaagcct ccccggcggc ggcacggtcc cagcgcggac
     2341 gcacccgagc tcccgcgacc accgccagca cgggctgggc aactgccgtg cacagcagtc
     2401 cgacggccat cgcgagcggc ccgaagccga gtgctgccag cacgatcgtg accgcggcac
     2461 ccagcaccat cccacccgcg tccggcagca tccggcgccg gaagtccaga tcgcggtgca
     2521 tcagcgccat ctgcacgcca ccgatcgccg tgaacggcag gctgagcgcg gcgatccgga
     2581 tgagcgtggc gggtgccccg agcgcggcgg cgagtggttc cgccgcgagg agcagcacaa
     2641 cggtgagcac caggccaccg ctcgcgctca gcgtcagcac ggtgcccgcg agtcgtcccg
     2701 gatccaggtt cgtccggctg atcacgtcgt agacgcccgc ggactgcacg acctggccga
     2761 tgttgaccag cgacaccacg agcgacaccg cacccaggcc gtcctcggtg agcagggccg
     2821 cgagcaccag cgtgaccgcg acctgacagc ccttgctgac cacgttgacc gcgaagagcc
     2881 acagcgatcc ccgtaccgcc cgctcaccga cccggttcgt cacgcgcgtt tcctggccgc
     2941 gacgacgacc agcagcaccc aggccacgac gatcgccacg ccgtccaccg tcacgtcgac
     3001 ccggcggccg aacagcccga tgatcgcgct gttcacgaag tacaggtgtg cgaacggaac
     3061 cagcagcgcc accaccgcga agccggtgat ccgccagtcc cgttccttcc tgcgccgcca
     3121 gcacaccacc gcgacggcgg ccatggcggg caccgcgatc aacacgtcac ccggctggtg
     3181 caccaccgcc acgaccgcgc cgacagcggt gatcaggtcc gcgaccgacc ggctgtcgga
     3241 gtcgccgccg tcgagcttcc tcgcgaggta cgcggtcgcc gccagcacac cgaccagtgc
     3301 cgtgagctcg gccgccggcg gcagccagtc cgtcacccgg aagaacaccg ccggaagatc
     3361 cacccgctgc gccgtcacgg aatccaccgc gccatagctg gtaccgctgg cgtgcgcgag
     3421 attcgccgag atcacgtcga ggaacggccc gacgcctccg ccccggtaca ccagcagccc
     3481 caccacgggc aggctcgcga gcgccgcgat gaccgtgccg ccgagcgcga cccgccgcga
     3541 tccgcgtgcg aacagcagaa tcgccagcgg caagccgaac tgcggcttca gccacgccac
     3601 cgccagcccg agcgccgcca cccgcggatg actggacctg gccagcaacg ccgccgccgc
     3661 acccaccgcg atcaacgggt tgacctgccc cacgtacagc tgcgccttgc ccacctggct
     3721 cgtcaccagc agcgccccga tcacgacggt gcccagcacg agcgggagct tggcccgccg
     3781 cgcggccagc agcccgagaa ctcccaggag caccagagac gccagggtga acgcgatcgc
     3841 gccgatccgg tactcgggca acgcgaacgg caggtgcagc accaggtggt acggctggta
     3901 gaggttgaag ttctgccgca ccggccagtg ctcgaacatc gccgccgggt cgtacgggtt
     3961 gccgcccgcc aggaactccc ggatcgggaa gtacagcgcg tcgcggaagt cctgcagccg
     4021 ttcctcggcc aggttctccc cggtcggtgc cgggacctcc cacgacggac gcagggctcg
     4081 tgccgcgctg agtgcgccga tgacggcgac cgcgatggtg atgagcgtgc gggtgtcggg
     4141 cttggtcgtg gtgatcacgt cagcaccacc gccaccagga ccgcggacgc cggcagcacc
     4201 gcgagagccg cggccaggtc aaccggttcg cccccgccgt ccgcgaccgc gatcaccgcc
     4261 gtgccctcac cgggctcggc cgccttgtcc ggcaacgact ccgccagcga ctcggcctgc
     4321 gcggtcagtc cgtgatccgc gggaatcacc cgcaccggcc gggccgccgc gacgcacaac
     4381 gccgtcagcc ggtcgagcat ctcggggtcg tcctcgcgga ccagcgccac gggatgccgc
     4441 aacccggccg tggcaacggc ggcccgcacc gcggcctccc cggtgcgggg cctgcgcagc
     4501 gctcgcaggg cggccgtcgc gatgcccgca gccagcgccg cggccagggc gagccctgcc
     4561 gcgagcttcc agtccggcgc cacccgcgtg gtctccgggc gttcgtcgag cacgcgcaac
     4621 cgaccggccg gagcgagcag gttcgcgtcc gccacggcct tcgccaccgc ggtcacggcg
     4681 gcaccggcct gctcgtccga tcccgcccgc accgacaggc gggcgagtcc ggacgccgga
     4741 accagctcca caccgacgcc gtcggcgatc tcgcgcggcg tggtggacgc tgcccgcgcg
     4801 gcggcctcca gcacggtcgg gctgtgcacc atctggacga tcgcgggcat cgcgagcgag
     4861 gccacctcgc cgtactgggc agcggagtcg gtctgcgtga ccggcacggc gagcacggcg
     4921 atccggctct cgtactgctc gccccgcaga gacgtcaccg ccagcacgag caccgcgacg
     4981 accagcgcca ccgcggtcgc ctccagcagc gtgcgcttgt tcaccgttgt tctcccccaa
     5041 tggttcggag cagttcgtcg taggacttca tgaaggtgtg cgggtcgtgg tcgcgctcga
     5101 cggcggcccg gcccgcggcg ccggccgcgg cgcacgcccg tgcgtcgaac aggaacgagg
     5161 ccagcgcggt cgcggtcgtc gagggggagc ggcggggcac cagcacgccg ccaccaccgg
     5221 acaacgcctc gcgcacaccg tccacatcgg acgccaccac cgggcggccg gcggccagcg
     5281 attccagcac cgcgatcggc atgccctccc agtcgctggt gagcaccacg acgtccgtgg
     5341 cctccagcag atccgggacg tcacaacggg tgccgaggaa ccgcacgcgg tcacccacac
     5401 cgagctcctc ggcgcgccgc tccaggtccg cgcgcaggct gccgtcgccc gccagcagca
     5461 ggatcgcgcc cgcgaccatc gcccacgcct ccagcagcac gtcgtgccgc ttctggggtt
     5521 cgaggcgcgc cgggcacaac gccaccggca cgtcgggacc gatgccgagc actccgcgga
     5581 tcgaggcccg gtcgactcgg ggcggctcgg cgaacaccgc gttcgggatc acctcgacgt
     5641 ccacacccag cgcacgcaac cggtcagcgc tcgcctcggc aacggcgacc accgcacgtg
     5701 aggtacgccg gagaatccgt gccgcaccac cgagatccga ctcggagaca ccgtggaaca
     5761 cggtcgccac cggccggcca cccgccgcca tccgcgccac gaggctcgcg gacacgttgt
     5821 gcgccagcac cacatcagga ccgaaggagc gcaccgccga acgcacagcg gaaacagcgc
     5881 gcagcactcc ggagaccctg cgccgcggca ccggcacgtc gaacgtcgag aaaccctgcg
     5941 cccgcaaggc ctcggcacga tgcccgccgc cgctcgcgac acccgactcc cagccgaagt
     6001 cgccgccggc ccgcaccatg cccgcgacga cggcctcggc tcctccggcg cccatctcac
     6061 tgatgacgtg cagcacacgc atcgcgctca ctctcctcac ggcgcaggtc ggccgcgatc
     6121 gccaccgcga ccagcgacca gatcggcagg tagtactgct cggacaggaa ggtcgccgcg
     6181 accagcgcgg cgatcagcga cgcctggacc gcgagcatcg accggtcggc acgtgcacgc
     6241 aggacgcgtt ccgtcgccac gaacgccagc gcgaccgcgc cgaggaagca ggcgagaccg
     6301 ggcaggccga gctccgcgcc gatctccagg tagatgttgt gcgccaccgg tgactgctcg
     6361 tcgatctcgg cgttgcgcga ggccgccggg tactcgctgc ggaacccgcc cggcccgacg
     6421 ccgagcaccg ggttgtccgc cagcatgcgg gcggcggcct gccagcgcag ctcacgagtg
     6481 tccacattgg ttgcggcgat gtacgtcttc tcggcgagcg cccgctccag caccggtccc
     6541 gcgaacacca cggcgccgag cccgatgacc gcgagcccgc tcaccgtcgc cgtgaccgcg
     6601 cgcatcgaca cgccgcgccg cgccacgagc cacacggcgg cgaacgccag tgcgaggcca
     6661 ccaccgcggg agaacgtcgc cgccgcgccc gccgcgagga tcgcgcctac cggcagcagg
     6721 aacctcctgg cgggcagggc gatcagcagc ggaagtgcca ccaccaggaa gtaggcgagg
     6781 tcgttggggt cctccagcgg gccggtcgcc cgtgcctcac cgtcgacgac caggctgtac
     6841 agcgcgccga ccgccgcgct cacggcaccg cccaccgccg ccgcgagcac cgcccgcacc
     6901 ggcacttcgc gtgccgcgac gtcggccagc accgcggtga tcaccaggaa cggcaggaag
     6961 cgctgggtgt aggccgccgt gaacggatca gcggcgtgca cggccgacga ggccagcaac
     7021 accacggcga acagcgccag caacgcgtgc agcggatgcg gcgcgggcag acgccgctcc
     7081 cgcacccgtt gcgcgaccca ggacacgatc agcagcgccg gcaccacctt cgcgaggtgc
     7141 gggtgcacct cctgcaggta gccctccagc ggggccagca ggaccgtcgc gcacgcgagc
     7201 acgcgcagca gccacgtcat ccgcacagct ccgtccggcg ctcccggagc agctctgaca
     7261 gccggtcgac gtgcgctccg gtgccgacga cgtcgaagtt ctcgcgcagc gacgaaagca
     7321 cccagccgag cagcgcggcc ttctcggtac ccggcaccgc catgccgggg aagaactcca
     7381 tcccgggcgc ctcggcgccg ctcagcacgt cggtcgggtg cagcagcaac gacggcgctg
     7441 tgccggtcag caggcacaac cgcagtgcgg cgcggaagta cccgcgtgcc agccgtggcg
     7501 agatctggtg cagctgcaac aggtacgcgc cgtggatggg cacgcgcagc aacggcatgg
     7561 tggtcaccgg cagctcgacc agaccggtgc cgtgccagcg gaacggggtg ttcggtgcca
     7621 gcaccttgtc gaagccgccg aagagatctc cggcaccttc cgcccggtcg cgggcggtgc
     7681 ggttgtggta cgccctggcc agcgggccga tccacgtcgg cagggtgctc gcgtcgtagc
     7741 ggtagccgcg cgcggccagg atctccagca gtgccggggt gacgctgtag ccgggaccgc
     7801 ggaacccggc cggccgggga gcgcctgcgg ccgtgatcgc gtcctccgcc ttgacgagct
     7861 ccgcctccag ctcgggccga gagtaccggt gcagccaggg ttcgtggccc cacgagtggt
     7921 tggccacctc gtgccccgcc gccacgatgt cgcggacagc ctgcgcccca tcgtcgcgtt
     7981 cggcgtccgc cccgaccacg aaaaccgtgg tggtgagccg gtgttcaccg aagacgtcca
     8041 gcagccgggg cacggccgtg gcgaggaagc tcggcctgct ctcccagtcc gggttcccgt
     8101 gggtcttgag gtaggcccac aggttgtcca ggtccagcga gacgctcgcg ggtctcatcc
     8161 ggccacctcg gcggtggtgc ggttcgggga gcccagcacc agcacgccgg ccacgacgag
     8221 cgtcatgccg aacccgacgg cccactccca gcccggtgtg atccggtcgc ccagcatgcc
     8281 gatgccgatg accgaggtga gcaccacggt cgtcgcgtcc gtcgccgcca ccgacgacgt
     8341 ggccgtgccg cgttgcaacg cgaccgcgag gcaggactgg ccgaccagcg ccgccacgat
     8401 catcaaccag gtcagcgggt tcagcagcat gtcggccggc gactcgtccg cgaccgaccg
     8461 gccgatgatc gccacgaccg cgaaggcggt gccggcgagc accgagacga tgacggagtt
     8521 cgagccctgt gcggctcgtg agcagaacac gatcacgagc agcggcagcc cgagcagaac
     8581 cagtcccggc accgtgggga tgtccttcgc caccgacgat tccgacgccg tgaccagcag
     8641 gacgagcccg atcgccatca tgaccagcac cgcgatctcc agcggccgca cgcgccactt
     8701 cagcaccagc aggccgaacg cggtcgcgag cccgacggcg cacgaagatc ccgcctgcac
     8761 caggtacagc ggcagctcgg cgcgggcgag gaacgcgaac ccgaaaccgc ccacctggcc
     8821 cgcgaaaccg aacaggtaga gacggtcctt ggccagccgg gcgaggagtc ccagcccggt
     8881 gcccggcctg acgtccgccc gttgtgcggc aacggtctgg gccacgatgc ccaagccgta
     8941 cagcgcggtg gagaaaacga gctcaaggta tccggacatg caggacctcc ctcgtcaagg
     9001 ctccgaagaa tacggagccg cgagggcgct ccccattaga gggatatgcc acaactcatt
     9061 gcgagaattg gcagacgaca atcgctcgaa agtggaagat atttgctcga aagggtgacg
     9121 aatcagagtt cgatgacggt gccgtccggt ggcacctcga cgccagcctc acgcagcttc
     9181 gcggcctcgg gagactccgg gtcgagcacc gggttcgtgt tgttgaggtg ggtgtagatg
     9241 cgccggacgg aggggaatcg tcgcagttca ggaaggctgt gtgtgatggg cagatggccc
     9301 atggcggcct gaccggacga gctgccggtg gccgagccca tctcggacgc cgcgtagaag
     9361 gtgccgtcga gcagcaggca gtcggcctcg gccacgacgt cgtcgaaacc ggcgggccac
     9421 gacgccaggc aaggcgcgta aaccagcacg ccacccgaaa tcggatcctc gaagcggtat
     9481 gcgaccaccc aatgcccgtc cacggtggag gaacgggcgt atttgggacg cttgccgctg
     9541 atcggaatcg ccgagaccag cagcccaccg aggtcgagcg gctggtccgc ctcgacctgc
     9601 cgccacgcca ccggcgcgta gccgtcgatc accgtgcgca ggtcgaactg gtcccgcagc
     9661 gcgtgcagga ccggtcctgg tgcccacacc gtcaggccgg ccccgccgcg caacgtcagc
     9721 agtcccagcg tgtggtccag ctcggcgtcg gtgaacaggg caccgcggat cggggtgtca
     9781 cgcgggccgg ggccggggtt cagcggcgaa caggccgcga cctgcgtgcg gatgtccggg
     9841 gaagagttga ccagccacca gtcggtgccg ttgccgctga tcgccaggca gtcctgcgaa
     9901 cgcgacggca actcaccgga acgagcgcgc acgcacagag cgcacgcgca gttccattgc
     9961 gggaagccgc caccggccgt ggtaccgagc agaaccgctt tcaagacatc ttcctcattg
    10021 ccatggccgg aacctcggaa ggcgccatct ccgtcgccag gatcaggtcc acagtggacc
    10081 ggtcggggga cagcgagcac accgggtcgg tgttggcggc gtcaccggtc aactggaacg
    10141 cctggcacct gcacccgccg aagtcgatct ccttgcgcgg gcacgagcgg cacgggtcct
    10201 tcatccactc gtagccgcgg aaagcgttga aggaagctga gttgtgccag atgtcgtgca
    10261 acgacgagtc ccgcacgttc tcgatctgca acgacgagat caccgtggcg gcgggacagg
    10321 ggagcacgtc gccgttcggt gccaccgtca gctgccgcgc gccccacccg tacatgcagg
    10381 gcttcggatg agcctcgtgg tagtcggcga tgacgtagac gatctccatc cgcccgcgca
    10441 gacgttcctg cgccgcggcg acgatcggat cggccaccgc gagctgttcg cgggtgggca
    10501 gcagaaccgc ccggttgcgc agagcccagc cgtagtactg cgtgttggcg agctcgaggc
    10561 gttcggcgcc catttcctcg gccatcgcga tgattccggc gatgttgtcg aggttctgcc
    10621 ggtgcagcac cgtgttgacg gtgagtggca gaccttcctc acggatgtac gccgccgcct
    10681 ccaccttccg gtcgaacgcc ttgatgcccg cgatccggtc gttgccggcc ttcgtcgcgt
    10741 cctgcaggga gagctgcacg tgatcgacac cgcgagaagc cagctcccgc agccgttccc
    10801 gggacaggcc gactccggac gtgaccaggt tgacgtagca gccgaggctg ttcgcgtgcg
    10861 ccaccagctc cggcaggtcc ggccggagca acggctcgcc gccggacagg tggatctgca
    10921 gtgctcccaa agaccgcgcc tggtcgaaga cccggcgcca cgactcggtg tcgagctcgg
    10981 cgttgcggcg gaccagttcg acggggttcg agcagtagcc gcactgcaac gggcatcggt
    11041 gcgtcagctc ggccagcagg ccgaaaggtg cctcagccat cgacgtccac caccctccgt
    11101 tccaccagcc tggccacgag ctcggcgatg tcctcgggct gcacgcccgc gtacacatcc
    11161 cctagcgcca gcgcgatgtc gccgaccgac cggaccccgt cgcacaacga cacgacggag
    11221 gcggcggtct cgttcagcac cagcacacct tcggggaaca ggacgacgtg cgcttcccgg
    11281 atctggtcgt aggtgcactt caccccacgc cggatgcgcg gcacggcgtc cagggcgacg
    11341 acggacgtca cggcttgccc ttgcccgagt agtagtcgac ggtgtccagc acggcacgca
    11401 gcacgtcgca cttgaacgac aacgcggcga tggccgcttc ctgctgggca cgagtacggg
    11461 agtgctcgac cacgatgtcc aaagtggcct gtccctcacc ggcgaccgcc tggatgcggt
    11521 tggtgaagta ggcgaagccc tcctcggcga tccacgggta ctgctcccgc aatgccgcca
    11581 aacgcttgcg catcaaggca cccgagaaca tctccgtgag gccggaggcg atggcctcga
    11641 cccacggctt ggtgcgcgcg aagttcacgt aggcgtcgac ggcgaacctg gtgccgggca
    11701 gcacatgccg ttcgtcgagc acctcttccc gcgtcagccc gacggcttcc gcgaggcgga
    11761 tccagttctc ggcgccgccc tcgcccggct gcgtgccgtc gtgccagatg atccgttcac
    11821 gccactgacg tcgaatgtct ggtatcgggc agttggaaag gatcgcggcg tccttctgcg
    11881 cgatgcatcg ctggtagtac cagcggttcg cggcccacgc ctgcagctcg tgcttgctca
    11941 gctgacccgc gtgcatgcgc aggtggaacg ggtggctgtc ccagtaccgg ggcgcgaggg
    12001 cgcggagctc ggcgacgaac tcctcgggag gtacagcggt catgggcgga tactcctcgg
    12061 ctgggggacg cgcggcgagg cgtggggccg gggttcctgc ccgcgaaacg gcaggaaccc
    12121 cggcaaaagc ccaacgtcag ctgcgggctg cgtaggcggt gacctccatc ggcgtctcga
    12181 agtcgcggaa gtcgggcttg acccactcgc gcttgacctc gggaagcttc tgctcggcag
    12241 tgttgacgac aacgttcatg gcgcaactcc tcgggtctcc ggccggcgtg cccaattgct
    12301 gggcgcgcgg cacttccgtg gggcgcggcg gcgaaccaca cgttatgtct tcccggcggt
    12361 cgaggtccag accgtacata aagttaccta aagtcatcgg aggggtgacc cgattggtgg
    12421 atgcgctcct gactacacac cgtggttgta tcgggaggcc cccagcccgc accttccgac
    12481 gcgggctcgc cgtcgccgca cgacgcgaaa gttgaggggt cagcacaatg ggtgctcgtc
    12541 gaagtgcgta cgccggcgtc ctcgcacttg cggtcggact gtccagcagc ccgctggcgt
    12601 ccgcggcaga gagcggcgaa gtcggcacga tggccgtcaa aacgatcgcc accggcctca
    12661 agcaggcctg gagcatcgac ttcctgccgg acggcaccgg catcttcacg cagaaggacg
    12721 ccaagaccgt ctccaccatc accaaggacg gcaaagtcac gaaagtcggt gacatccccg
    12781 gtgtctcggt gacgaaggaa gcgggcctgc tgggcattgc ggtgtccccg acgtacgccg
    12841 cggacaagac gctcttcctc tactacacca ccggaagcga caaccggatc gccacgtgga
    12901 agatcggcga cacggccacg aagcccatcg tcaccggcat tccgcgcggc tcgcagttcc
    12961 accacggcgg ccgcatcaag ttcggtcccg acggcttcct ctacgccggt accggtgacg
    13021 gccagaacgg gagcaacgcg cagaacaaga actccttggg cggcaaggtc ctgcgcatga
    13081 ccaaggacgg caagcccgcg ccgggcaacc cgttcaactc gctcgtctac tcctacggcc
    13141 accgcaacgt gcagggcctg acctggctgg gcagccagct ctacgtctcc gacatcggcg
    13201 ccagcaaggt cgacgagctc aacaagatcg acgccggcaa gaactacggc tggccgacct
    13261 gcgagggttc gtgcggcacc gccgggatga ccaacccggt gaagcagtgg ccgacctcgc
    13321 aggcgacgcc gtccggcctc accacctaca agggccactt ctacatggcc tccctcaagg
    13381 gcggcacgtt caagctcacg ccgaacggtg ccggcggcaa gatctacacc aacctcggcc
    13441 gcacgcggga cgaggtcgcg ggtcccgacg gctcgctctg ggtgatcacc cctggcggga
    13501 tccacatcgc cgacggcaac tgaccacacc ggactcggct acccgaggta gttgagaaac
    13561 gtccctcgcc tcacccgctc ggaggcgagg gacgtcccac acatccgatg accgttgtgg
    13621 gtttatccga cttgtgattg ggcaactacg ccctgcaacg ccgccgccgt agacaaacac
    13681 gagcggacat tgaaggagag cacatgcgtg ctcgtcgtat cgcggtggcg gcagcctgcc
    13741 gtggccgctc cctatgcgtg atcccggcct ccgcgcagga cggcccgccg gttctcgccg
    13801 aacggacaat cgccacgaag ctggacatcc cgcgggacat cgagttcctg ccggacggca
    13861 gcggcatctt caccgagcgg gacacgcgca agatcaagaa ggtcaccggc accaccgtca
    13921 cggaactgga cacggtggaa caggcccaga cgaccggtgg tgagggcggg ctgctcgggc
    13981 tcgccgtgtc gaagaccttc gcgaccgaca actcggtctt catctactac tccacggcaa
    14041 gcgacaaccg cgtcgcgaag ctgcggctcg gcggtacacc gcaggtgatc gtgagcggca
    14101 tccccaagaa ccgctaccac aacggcggcg gcctggagtt cggcccggac ggcttcctgc
    14161 gggcgaccac gggtgacggc cagaacgcca gcacggcgca gaactggaac tcgtcgggcg
    14221 gcaaggttct ccgcttcgcc accgcgggca ggcccgcggc cggcaaccct cgcgccggca
    14281 gcatcgtcta ctcgatcggg cactgcaaca ccgcggggat gaccaacccg gtgaagacgt
    14341 ggcccaccag tcaggccggt ccggccggca tcggctacta caagaacgcg ttgtacgtcg
    14401 gtgctgtcac cggcagtcgc gtgtggaaga tcccggtgaa cggcaccacg ctcggcaccc
    14461 cgcaggcggt gttcacgagc tacggccgcg tacgggcggt ggctccggcg ccggacggca
    14521 cgttgtggct gggaacgtcc aaccaggacg gccagccgga tgcgaacgac gaccggatcg
    14581 tctcgacgga cggctgagcc tgggcctagt tgcgggctgc gggcatccgg cggagctggt
    14641 ccagcactgc cggatcctgc agctgcatcc actggatcac ctcggtgtag gtggcgcaca
    14701 ccgtttccgg cttgtcgcac acgtacgcga ggaactgctc catcgcgttc gagaacgccg
    14761 aaccgttcca ctcgttgaag tggttgccga tcacgagcgg cgcgcggttg ccgttcaacg
    14821 cggcctggtg caccgacttg tacgtgtcga agacgatctg ggcgaactcg gtcgcgcggt
    14881 ggggttcgtc cctggcgccg ttgagcgcgt accagaggtt gaagtccatc atgacgacct
    14941 gcctgcccag cgcgggaacc ctcacctcgg gcatcgggaa ctcgtacagt ccgttttgga
    15001 tggacggcca ctgcacgccc agcgcaacct tgctggtgtc gtaggccagt ccgttggccg
    15061 ccatcgcggg gaaagcgtgg tcccagttgc cttccaggca cggcgtccgt ccaccccgga
    15121 cagcgccgtc ggcgagcttg aagcctgcgg cacgtgccct gtccacgatc tgcttgaact
    15181 gggcgagctc ctcgttccac gccttgctgt cccacttgtc gaccgacggc tgggtgccgc
    15241 cggagcagaa gtggccgttg tagtgcgtgc cgatctcgtg gccctcgtcg atcacctggt
    15301 tgaggtagcc gatgcgggcg gcgatgtcct gtttgctgcc accgaaggag atgtcggaga
    15361 cgccgcgctt gagtcccgcg ggcggctggt actgcatctt gtcctggtcg gccagcatgt
    15421 acacgccgga cagcagaccg gtgacgtgcg ccttcttctc cctggcgatc ggcaggacct
    15481 tgtcccagtg ctgcttggag accgcgccgt cgaaggagaa cagcacgaac tgcggtggct
    15541 tctcaccggg tgcgagcttg tgcatccacg gctgctgctg cagttgttcg gggctcggcg
    15601 cgggaactgc cggcgtgggg ccggcgtcct tgggggcggg cagccgaggt gccatcggca
    15661 ggggaccggc gtccgcctgg ctctgctggt ccttggtcgg gccgagagtc atcaccagca
    15721 cgagggccag cgcaagcgcc aggcccgtgg tcaaccatcc ccaccgtttc acacttatgg
    15781 agacgactgg tcacccgaag gggttgcttc attacgcaac gggttcggcg atcaccacgc
    15841 ggttggcctc gtaaccctgc tgacctccga tccacgtgcc gccgcaggtg accagcacca
    15901 accggcgcgg cccgcgcggg ccgaagaact cgacggcgcg ggcaggcagt tcttccttgc
    15961 gcaccgtctc gatctggttg atgcggaact tgaactcctt gccggcactg tccgcgatca
    16021 cgacctcacg gccgttctgc gcctgccaca gctcggcgaa gggacccctg gcgcccttcc
    16081 agtcgacgtg cccggcgagg accgtcgcgc cttcctgccc cgcgagctcg gcaccccacc
    16141 aggtggcctc gccgatgccg tcgggaacgg gcagcacgcc gtccttcacc tcgcggcgga
    16201 ccagcgtggc cgtgcctccc gaaggcagcc ggaccgagcc gggaccggcc ttgggcggcg
    16261 ccggttgtgg ttgcgtgggc tccgcgggct tggcgtttgc cgtgttcgcg ccaccgacca
    16321 gcccggtgag gtcggccccg cggccggtgc tgaggctgtc agcgaccggc cccggcccga
    16381 ccacggggat ctcgtccgcg accgcgtgcc ccttgagcac ctcggtcccg gacgcggtga
    16441 ccagcacgct ggtggcggca acacccgcca ccagcgcgcc ggtcagaaac gccttgggac
    16501 tcactgcctg cgccacacca ggaagcctgc cagcgccgca ccgagcagca cgaggccacc
    16561 caccgcgagc atcacacccg gacgcagctg cgtttcgaac gacgcggtcg cgacgggcgt
    16621 cttgccgtcc tgaccggccg ggatcgtgct gggcacgacg ggcttgttgg gcttgttcac
    16681 cagttcgagc gcgagcgtct gtcctgccgc gagcgtgccg cacgaggccg gtggtgcctt
    16741 cgggtcgaag aactcctcgt accccttcgg tgccgccacc tcgacgaggc agatctcctg
    16801 cggggtgcgc aggtccggga cttcgaccgt gccgtcggcg ccggtctgca gcaccagcgg
    16861 cttgccgtcg gtgccgacca gttcggtgtc gtcctgcttg agcgcgggct tcgtctggtc
    16921 cttggacgtg acgcgcaggg cgacgcccgc gatggccttc ttggtctccg agtcgatctt
    16981 cgtgatcttc accttgccgg gcgcggtctt ggcctgtccg gtggcgttcg cgctcagctt
    17041 cttctcgccg cccgtggtga ccatgcgctg catgttgtcc gtcgagatcg gctggtgcac
    17101 gaccggcttg tcggcggggg agtccgcgtt ggccgcgatc gagggcttcg ggcccgtggg
    17161 gaggatcttg atcgtggccg ggctgccgtc ggcgcccgtg gtggccttgc cgccgacact
    17221 gccgtcgacg agcgtcgcgt cggtcagcgt gaagtcgatc ggcgcgctgg gcacgccctg
    17281 gccgttcgcc ttgaccagcg acacggtcca gctcgactcg gtgccgatga tcagcggttc
    17341 cttgggggcg gtggcgctga gcgtccacgg gccgcggttg gcctcggcgt cggctttcag
    17401 gcgcgcgacg gtgtccatga cggcgggcgg cagcttcgag gcgtagaacg cgctgtcgta
    17461 ggcgaggtac ttggggtcgg tcgcgccgag gttcacgttg ccgtcgacag gagaggtcca
    17521 ggtgtggagg aggtgcgcga gcgcggccgc ctcttccgcg gacttcgtcg tggagtagcg
    17581 cagcaggagg taggagatgt tcgccgcgat gtcggacggg agcttcttgc ccgccttcgt
    17641 cagcagctcg tcgccttcct tgtagccgac gttgctgtcc ggcgcgggca gtgcgtactg
    17701 cacgcaccac acgtgcttgt tctgccagac gtaggacccg tgccactcgc tgcccggtgt
    17761 ggcgttgggc tggagccctg acgcgttgtg gccgatgccc ttgacaccga ctgctgtcgc
    17821 cgtcgtgggt gcggtcagga gtgcgagacc cgagaccacc gccacggcgg caagacgttt
    17881 ccagcccatt ttggatcttg gtcccctctg acctgtggta actccgcgtg cgagcctggc
    17941 ggtaccccac accgggtaca agccgccacg agggggaagt gtgtcgtcac cgtccgtgtg
    18001 aatgtgattg aaatgtgacg cgcgttactc gcttcgggag tgacacgccg cgacacgccg
    18061 tagtctcact acgctccgga gttagcgcag tatttgcgca cgtgtgatcg tcgtcagggg
    18121 taaagtcgcc tttaccggcg gggaacctgg cacctagcgt gctcgttgta cccgtgacgg
    18181 cgtaaagcaa cgccccagga ggaccaggtg cgctccagca gcaacccggc tttccgtaac
    18241 ctgccgaccg gcggcgggta cggaggctat gcaggcttcg gccagccaga ggccggctac
    18301 cagcaggctc cgccgccgct gaccagcgag cggcccatga cgatcgacga cgtcgtcacg
    18361 aagaccggca tcacgctcgc cgtggtggcc gcgaccgccg tcgtcacgta cgtgatgcag
    18421 tggtggaacc ttctgttccc ggccgcgatc atcggcctcg tgctcgcgct gatcatcatg
    18481 ttcaagcgca tgccgagccc gccgctcgtc atcgcctacg cggccgtcga gggcatcttc
    18541 ctcggtgcct tcagcggcat catcggcgcc atgatcgacc gctggaccgg tccgggtcag
    18601 ggtgtcgtcg tgatcggcca ggcgatcatc ggcacgatcg gcgtgttcgc cggcatgctg
    18661 atcgtctaca agacgggcgc gatccgagtc acgccgaagt tcaccaagtg gatcaccggc
    18721 gcgatcatcg gcgtcgccgt cctcatgctc ttcaacctga tcatgagctt cttcaccgac
    18781 ggcggcctcg gcctccgcaa cggcggcgcg ctcgcgatca tcttcagcct cgtctgcatc
    18841 ggtctcgcgg cgttcagctt cctgatcgac ttcgacgccg ccgaccaggc gatccgggcc
    18901 ggtgtgccgg ccaagttcgc gtggcagatc gcgttcggtc tcacggtcac cctggtgtgg
    18961 ctgtacaccg agatcctgcg cctgctgtcg tacttcaact cggactgacg tcccgggggt
    19021 ttccggaggg cgcttcgctt cggcggggcg ccctccggcg tttgggggtg gaatgagcaa
    19081 gaggttcgga gaggcgatgc ggctgatgcg ccgccgcaac ggccaggact gcgaaaccgg
    19141 cttcgccatg ctgaagcccc acgcggcgga gcacctcgac gagctcatcg aggagttcca
    19201 ccgcgaggag gacgaccagg gcctgcgcgc ctggttgctg gagctgatcg gcgaagccgg
    19261 ggatcccagg gcgttgccgc tcttcgtcgc tcacctcgac gacgagcgct tcggggactg
    19321 ggcgatctgg ggcctcgaga agctcgacac caaggaagct cggacggcgc tctaccgcca
    19381 caggtcgaac aagcacacct aggggagatc cgtggatcac gcgtaccggc tggagatgaa
    19441 accgcccgcg gtcgacgact acctgcgcct gcgcaaggaa tcaggcctca gcgcgcgcac
    19501 cgtcgaagaa gccgagaacg gcatcaacgg cgcctgggcc agcgcacacg tcgtccacgt
    19561 ggagtcaggc gagaccgtgg gcatgggccg cgtgctcagc gacggcggct ggtacttcca
    19621 catcatcgac atggcggtgt tgccgcacca tcagcgcaag ggcatcggcg acgcgatcat
    19681 gacagcgctg ctggaccgca tcggcgaaca cgcgccgaac gcgtacgtca acctgctcgc
    19741 cgacccgccc ggccgtcgtc tctacgaacg gcacggcttc accgagagcg caccggcgtc
    19801 ggtcggcatg aggcgggtct aggcccgcca gcggacatcg ggcagttgcg tgcccacctt
    19861 gatcaggcag gtcgtgcaga gggcacctgc ctgggcacgc gacacccgct catcgggtac
    19921 cgagtgttcg cagacggcct cgtaaaagct gcgggaaccg ttggcttggt cgagggagaa
    19981 ggcatggcat tgcaggtcgt attcgctttg ccaccacacg tacggcatgt ccgaccctcc
    20041 ttgctcatcg cggtagggac ggactccccc tcgcctgatg acgccgttac gcgacgaatt
    20101 acgtcatcgg cagaaaggtg gcaggcaagt agctccgttc gggtgaagcg gagctacttg
    20161 caagcgtcaa tttgcagatc ttggggatct cagctcaggc gctcgatgac catcgccatg
    20221 ccctgaccac cgccgacgca catggtctcg agaccgaact gcttgtcgtg gaactgcagg
    20281 gaattgatca gggtcgtggt gattcgcgca ccggtcatgc caaacgggtg accgacggcg
    20341 atggcgccac cattcacgtt cagccggtcc aaatcgattc cgaggtcctg gtacgaagga
    20401 atcacctggg ccgcgaacgc ctcgttgatc tccacgaggt cgatgtcgga gatcgacaat
    20461 ccggccagtg ccagcgcgcg cttcgaggcc tcgaccgggc cgagacccat gatctccggc
    20521 gacaggccgg agacgcccgt cgacacgatc ctggcgagcg gggtgatgcc gagctctcgc
    20581 gccttcgtgt cggacatgat cacgagagcc gcggcgccgt cgttcaacgg gcagcagttg
    20641 ccggcgttga tccggccgtc ggggcggaag accggcttca gagaagaaac cgcctcgtac
    20701 gtcacgcccg cgcgcgggcc gtcgtccgcg gagaccacgg tgccgtcggg cagcgtcacc
    20761 ggagtgatct cgcgggccca gaagccgtcc gcgatcgcct tctcggcgag gttctgcgag
    20821 cggacgccga actcgtccat ctcctgccgc gagacgccct tcagcagcgc caggttctcg
    20881 gcggtctggc ccatcgggat gtagatgtcc gggacgacgc ccagcgaacg cgggtccacc
    20941 cactcgtccg caccggactg ggccaccgaa acggtccggg cctcggcgtc ggcgaacagc
    21001 gggttgtggg tgtccggcca cgagtcggag ctgcccttcg cgaaccgcga caccgtctcg
    21061 acgccggccg agatgaacac gtcgccctcg cccgccttga tggcgtgcag ggccatgcgc
    21121 gtggtctgca acgacgaggc gcagtaccgc gtgacggtcg tgccgggcag cgagtcctgc
    21181 ccgagcagga cggccaccac gcgcgccatg ttgaagccct gctcgccgcc gggcaggccg
    21241 cagccgagca tcaggtcgtc gatctgcgcg gggtcgagct gcgggacctt gtcgagcgct
    21301 gctcgcacca tctgcgcggc caggtcgtcc ggccgcacgt ccttcagcga acccttgccc
    21361 gcgcggccga tgggggagcg ggcggcggag acgatcacgg cctcaggcat cacgaaactc
    21421 ctcgttgaga gtcaaggtcg cggtcgagcg tagttaacgc ccgctcaccc cggccagcgc
    21481 acgtgacgcg aatttcgaaa ctcaggcgtg ccgcctttgc agccaccccg gcacgcggga
    21541 cggccgcagc gcgagagccg ccgccgaccg cctcggcaac gcgggcgtgc cccaacccgg
    21601 ccacaacccc accacctggc acaacggcgc cagcagcacg ccggccgcag cctcgtaacc
    21661 gacggcgctg gggtgaaagc ggtcggagct gaacatgtcg acgtgccgcg ccatgaactc
    21721 gggcgccagc aggttcgcta gcgacaccgg cactccaccc gcccgcgaca cctccgcggt
    21781 ctgcgcctcg gccagccgca ggctgtacct gtgcccgacg tagcgcaacg gctgcggaat
    21841 cggccgcacg atcccgagat cggggcaggt gccgacgacg acaccgcagc cggcggcgcg
    21901 cagcttgcgg acctgctcgc ccagcagccg cgccgactcg ccgacgccca gccgggaggt
    21961 gacgtcgttc gcaccgatga tgatcagcgc gacctgcggt gcgtcccgga cggccgcgtc
    22021 gacctgcgac accaggtccc gcg
//
