LOCUS       NZ_CP029361            22698 bp    DNA     linear   CON 31-MAY-2024
DEFINITION  Streptomyces globisporus strain TFH56 chromosome, complete genome.
ACCESSION   NZ_CP029361
VERSION     NZ_CP029361.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces globisporus
  ORGANISM  Streptomyces globisporus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7488586)
  AUTHORS   Cho,G.
  TITLE     Complete genome sequence of Streptomyces globisporus TFH56 isolated
            from tomato flower
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7488586)
  AUTHORS   Cho,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAY-2018) Division of Applied Life Science, Gyeongsang
            National University, Jinjudaero, Jinju 52828, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 29-MAR-2018
            Assembly Method :: canu v. 1.7; arrow polish v. SMRT link 5.1.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 37.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003147545.1-RS_2024_05_31
            Annotation Date                   :: 05/31/2024 02:17:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,917
            CDSs (total)                      :: 6,829
            Genes (coding)                    :: 6,492
            CDSs (with protein)               :: 6,492
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 337
            CDSs (without protein)            :: 337
            Pseudo Genes (ambiguous residues) :: 0 of 337
            Pseudo Genes (frameshifted)       :: 240 of 337
            Pseudo Genes (incomplete)         :: 121 of 337
            Pseudo Genes (internal stop)      :: 7 of 337
            Pseudo Genes (multiple problems)  :: 31 of 337
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:15:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3205275
            Orig. end                         :: 3227973
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029361.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22698
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="18"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22698
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22698
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12698](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12698)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            284..1285
                     /locus_tag="DIJ69_RS35345"
                     /old_locus_tag="DIJ69_14345"
     CDS             284..1285
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126128.1"
                     /locus_tag="DIJ69_RS35345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14345"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_167468550.1"
                     /transl_table=11
                     /translation="MATQHHSSALPAPAVPAAYPMAKPGYGKRSAPGQQPRIRDDFAML
                     PTRERYVAGFVDHLPDGAAMSVKQLAKQLPLYGQQAISTALKALSVAGHLRRVRCAVGA
                     GDETRWVFRTFWSRTARDNEWWNTYLATEAATRTAAPVEPPAPTAVPPQRTPPQPTDTE
                     PSPPAREAISAERTQTTALSPAYLALARLGRDDHRLGLSADDCTTLEPLAAQWLDRGVT
                     TDYLTNALTAGLPAQIDSPVGLIRRRLIDKLPPRLPATASTPTDTPAPTRRLLVECTDC
                     GRPGPPEALPDGLCRPCHQTHTTHGNTTPPDPTELASVKAHMANLRTLLKPV"
     misc_feature    complement(1296..1307)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.62"
                     /tool="antismash"
     misc_feature    complement(1467..1482)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     misc_feature    complement(1480..1494)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            1643..2585
                     /locus_tag="DIJ69_RS14355"
                     /old_locus_tag="DIJ69_14355"
                     /pseudo=""
     CDS             1643..2585
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354558.1"
                     /locus_tag="DIJ69_RS14355"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14355"
                     /product="tetratricopeptide repeat protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAHCGGNPVGAVELLVGAIASAPTAPEPYAALAELWQGRRSDGLK
                     ESLEEEGSLSAVLAQAYFLFLDGDMDDAVMALGSVTGVRPDVAWGAAPWFGDARFLGAV
                     SAAALAEACLRTLDYGHDLDTDAMRERFAPWFHALDVVSERDPVPESLAAMARLPRACG
                     RHELSFALCDRADAVDRVMWTALARAATWRVMGDLDQAAAAFEGALLLEPANWSLYLDL
                     ADVRAEQGDFAAAASLVRQGPGPRTSRSDPALGERRLPDPPVRLGRRPEGSDHPGTRAR
                     RHRLPEPADRLRVCGVAAPSGTGRRGPPDPPKL"
     gene            complement(2675..3634)
                     /locus_tag="DIJ69_RS14360"
                     /old_locus_tag="DIJ69_14360"
     CDS             complement(2675..3634)
                     /NRPS_PKS="Domain: PKS_ER (28-316). E-value: 6.2e-37.
                     Score: 119.3. Matches aSDomain:
                     nrpspksdomains_DIJ69_RS14360_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047546.1"
                     /locus_tag="DIJ69_RS14360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14360"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_167468551.1"
                     /sec_met_domain="ADH_N (E-value: 6.8e-07, bitscore: 27.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.6e-12, bitscore:
                     44.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDMRAALHDSYGPPEVLYEGRVPVPVRKPGEVLVRVHAASVNGG
                     ELYGRAGKVRLVTGRRFPQRTGLDFAGEVAEVDASVTGLRTGDRVWGILGRSSFGSAAE
                     YVSVRPRQIAYAPENVTLTEAASLPAGGTTSLTALRDKAGLRAGERLLVRGASGGVGSV
                     AVQLGKALGAHVTGLASVKNSDFVRELGADEVLDHRTTPLAELDRYDVIMDTVGTEHRL
                     LRTRLAPGGRLVSIAFDIDHPVRSIGYLLGSAVHGRQRVRFFSGNPKHDLFAELTAYVE
                     RGDLRPVVDTVHPLADIAAAHRALEAGGVRGKQVIRLV"
     aSDomain        complement(2687..3550)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DIJ69_RS14360_PKS_ER.1"
                     /evalue="6.20E-37"
                     /label="DIJ69_RS14360_PKS_ER.1"
                     /locus_tag="DIJ69_RS14360"
                     /protein_end="316"
                     /protein_start="28"
                     /score="119.3"
                     /tool="antismash"
                     /translation="KPGEVLVRVHAASVNGGELYGRAGKVRLVTGRRFPQRTGLDFAGE
                     VAEVDASVTGLRTGDRVWGILGRSSFGSAAEYVSVRPRQIAYAPENVTLTEAASLPAGG
                     TTSLTALRDKAGLRAGERLLVRGASGGVGSVAVQLGKALGAHVTGLASVKNSDFVRELG
                     ADEVLDHRTTPLAELDRYDVIMDTVGTEHRLLRTRLAPGGRLVSIAFDIDHPVRSIGYL
                     LGSAVHGRQRVRFFSGNPKHDLFAELTAYVERGDLRPVVDTVHPLADIAAAHRALEAGG
                     VRGKQVI"
     CDS_motif       complement(3134..3193)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DIJ69_RS14360_0001"
                     /evalue="3.90E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="DIJ69_RS14360"
                     /protein_end="167"
                     /protein_start="147"
                     /score="16.3"
                     /tool="antismash"
                     /translation="GERLLVRGASGGVGSVAVQL"
     gene            3746..4417
                     /locus_tag="DIJ69_RS14365"
                     /old_locus_tag="DIJ69_14365"
     CDS             3746..4417
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511003.1"
                     /locus_tag="DIJ69_RS14365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14365"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_044376693.1"
                     /transl_table=11
                     /translation="MPAQPSHNPTPATPDPGPEALRADARENRERILRAAREAYALHGI
                     DVPISAIARRAGVGVATLYRRFPTRTSLITEAFTEQLTECAGALDEALEDPDPWRGFCT
                     VVRKVCAMQAADRGFTHAFLARFPGDTAYAGELDRAEEGLALLVRRAKEAGALRPDFDV
                     SDVVLAMLANNGVANGAGPESAAASRRLVGYLLESFRAGPATGPLPPPAELELDRLGGT
                     G"
     gene            complement(4499..4945)
                     /locus_tag="DIJ69_RS14370"
                     /old_locus_tag="DIJ69_14370"
     CDS             complement(4499..4945)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123677.1"
                     /locus_tag="DIJ69_RS14370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14370"
                     /product="DUF1772 domain-containing protein"
                     /protein_id="WP_044376696.1"
                     /transl_table=11
                     /translation="MLDALEIVTTVIVGLLVGVEFSVAFVINRILDALPDDSAQLGRSH
                     GGRMLGALMPFWYIGSLVLSAIWAVAGWGEGGVGLVVAAGGLLLLSVVMSLLLLVPINN
                     RGKTWTPENRPEDWKEQMNRWDRYHYARVAILIAAFASLVTALA"
     misc_feature    complement(4965..4982)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(5024..5037)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.49"
                     /tool="antismash"
     gene            5037..5615
                     /locus_tag="DIJ69_RS14375"
                     /old_locus_tag="DIJ69_14375"
     CDS             5037..5615
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981641.1"
                     /locus_tag="DIJ69_RS14375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14375"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_044376699.1"
                     /transl_table=11
                     /translation="MSVQERKERERASRERLIVATARELAEQQGWDAVTTRRLAERIEY
                     SQPVLYSHFRGKREIIGAVALEGAAEMAAVLRAAASGADGRRARVAALAHAYLEFAERN
                     PAVYDALFQLDGGLAFAQEDTPEPLKDAFAALLETLGEVAGEGVHPALFTELFWSALHG
                     LATLTRAGRLLPEGAEQRLDLLVERLAVL"
     misc_feature    5043..5054
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            complement(5685..6905)
                     /locus_tag="DIJ69_RS14380"
                     /old_locus_tag="DIJ69_14380"
     CDS             complement(5685..6905)
                     /GO_function="GO:0000009 - alpha-1,6-mannosyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004376 - glycolipid mannosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006506 - GPI anchor biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010055996.1"
                     /locus_tag="DIJ69_RS14380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14380"
                     /product="mannosyltransferase family protein"
                     /protein_id="WP_044376702.1"
                     /transl_table=11
                     /translation="MSTLSPGLRPSPVRPPVPAAPEPRAARFRLSPADRDVLWLYLLTR
                     MSLWITAHFARWMFPAQSGVRETAPVLAPFQHWDANHYLHIARDGYFPAGAGPWTSGWD
                     NREAFFPGYPFLLRAVHTVVPDWTAAGLLISSVAGAVAVLALARIARTYLPEEGAGHRT
                     VVLFLLSPCAVFLAAGYTEALFLAFALPAWLAAMKHRWALAAVLTTLGTAVRVSGLFLA
                     AAIGLLFLLSVRAGGGRRTWRSAGWTLLPALPPAAYSWYLHAHTGDWMAWKHAQERGWY
                     RTFHTPWEAWANTWTGAFGGTQSTGYAFMFQAELAAMLVGLALVAWLVRRRRWPEAVYV
                     ALSLWALGTSYWYTSVPRATLLWWPLWIGLAALSLRRPWFRTVYLCLAAPVTTLVALTF
                     LTGRWAG"
     gene            complement(7015..7512)
                     /locus_tag="DIJ69_RS14385"
                     /old_locus_tag="DIJ69_14385"
     CDS             complement(7015..7512)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010055997.1"
                     /locus_tag="DIJ69_RS14385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14385"
                     /product="hypothetical protein"
                     /protein_id="WP_078955704.1"
                     /transl_table=11
                     /translation="MSEPQDPREPQDPLRSLFREAGEFGQALTAPETASGITRRGMRAQ
                     RRRMAVVAVGVCLVVGGGGAVAVGLLPVRPEPVAPATSPSPSYPSPAPSEGLPTEPPSP
                     PPSPSTTMPGSAGSEGPSGRTTEPGGPPTPTRTSTSTSTSTSTNTTPPTASATTDGGAS
                     TP"
     gene            complement(7505..8005)
                     /locus_tag="DIJ69_RS14390"
                     /old_locus_tag="DIJ69_14390"
     CDS             complement(7505..8005)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489040.1"
                     /locus_tag="DIJ69_RS14390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14390"
                     /product="SigE family RNA polymerase sigma factor"
                     /protein_id="WP_030718411.1"
                     /transl_table=11
                     /translation="MTVEEFEEFYAQAVARLTGQLYVMTGDLQEAQDVVQEAFVKAWVR
                     RGRLERDGQPEAWIRTVAWRLAVSRWRFRRRSADAWGRGSGAAEHVAPPDPDHVVLVDA
                     LRELPAQQRRTLTLHYLCDLTVEQIAGETGLSTSTIKTHLVRGRAALAHRLRDPRIEEA
                     PDV"
     misc_feature    7977..7990
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.98"
                     /tool="antismash"
     misc_feature    8087..8102
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            complement(8200..10068)
                     /locus_tag="DIJ69_RS14395"
                     /old_locus_tag="DIJ69_14395"
     CDS             complement(8200..10068)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379740.1"
                     /locus_tag="DIJ69_RS14395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14395"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_044376705.1"
                     /transl_table=11
                     /translation="MSAVAGTTAEPGQAGQGPGRPPENTEPPGPATPPDPARPTPASPS
                     VSPLRLLLARVRPHRGVLIRAGLLSLAGSGAGLAMPLMAKHAVDTFADGRSPVAPLVAL
                     TALVLAGACLSAYGSFLMSRTGEGVVLRARDQLVGRIMRLKVPAVDRLTPGDLQSRVTS
                     DTTLLRTVLSSGLVESFNSVLMLLGTIALMAYMDLTLLGVTLVVVVGIGAVTSLLMPRI
                     QRAQLKAQESVGAMGAALDRVLQAFRTVKASGAEERETAAVAAAARHAHDRGVTVAKWS
                     SVTEVTMTMSIQLAFLAVLGVGGARVASGSLEISSLIAFLLYLFYLMGPIGGLVEGWTG
                     LQSGLAAVRRIDEVVSLPGEPAQESSGLTKRNGGPLGVTFQDVTFGYGDERAPAHQGVT
                     FDVPTGGMVALVGPSGAGKSTVFSLLERFYDHEAGTITVGGRDIRDWPLAELRGSLAYV
                     EQDAPVLAGTLRENLLFAAPDADEKELASAVTRTRLDALVERLPEGLDTAVGHRGVTLS
                     GGERQRIAIARALLRHPRLLLLDEVTSQLDAVNEQALRDVILELAERTTVLVIAHRLST
                     VRHADRIVVLEEGRVRTAGTHEELIAGDELYRELATTQLAADGEGA"
     gene            complement(10001..10492)
                     /locus_tag="DIJ69_RS14400"
                     /old_locus_tag="DIJ69_14400"
     CDS             complement(10001..10492)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056001.1"
                     /locus_tag="DIJ69_RS14400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14400"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_030815349.1"
                     /sec_met_domain="PF13471 (E-value: 9.7e-23, bitscore: 79.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEMTMPRRGAGAGGVRLRAAVAAAFVLARLKPGRLRRVLARCS
                     RGARPASYAETLEVLEAVVATSRRCASRYGCLPRSVAVALACRMSGVWPDWCAGVWATP
                     PFSPHAWVLAEGRTVGEQAEAADLRPLMVVTVREGVQGERGGGDDGGAGTGGSGSGQTA
                     "
     gene            complement(10489..10740)
                     /locus_tag="DIJ69_RS14405"
                     /old_locus_tag="DIJ69_14405"
     CDS             complement(10489..10740)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126488.1"
                     /locus_tag="DIJ69_RS14405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14405"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_010056003.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.4e-25,
                     bitscore: 86.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.6e-13, bitscore: 47.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLRKGIAVTTTEYGGVLLDEKSGSYWQLNDTSVIVVETLAAGRA
                     PEAAVDRIVAEFDVERAEAESDVAELTRRLVEAKILRP"
     aSDomain        complement(10495..10740)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DIJ69_RS14405_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.80E-27"
                     /identifier="RREFam002.1"
                     /label="DIJ69_RS14405"
                     /locus_tag="DIJ69_RS14405"
                     /protein_end="82"
                     /protein_start="0"
                     /score="86.1"
                     /tool="antismash"
                     /translation="MKLRKGIAVTTTEYGGVLLDEKSGSYWQLNDTSVIVVETLAAGRA
                     PEAAVDRIVAEFDVERAEAESDVAELTRRLVEAKILR"
     gene            complement(10737..12698)
                     /locus_tag="DIJ69_RS14410"
                     /old_locus_tag="DIJ69_14410"
     CDS             complement(10737..12698)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056005.1"
                     /locus_tag="DIJ69_RS14410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14410"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_044376710.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.2e-29, bitscore:
                     101.8, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGQLRDYFVVLPDNAAGAAVAGQLPVPEAAAGRSSAPDATGPAR
                     EVDGTLTVAHPSGRPWVVARPLVREVSHLARGEDALVLIGPDRVPDAVLAGILEGARDR
                     TGLERRLARLPGLYHVVARLSGDSWIRGTATGLRRIYHARHPAAGTIASDRPAVLARLT
                     GAPLDDSALALRLLDFLPHPLSRRPVWRGVHETGAGYGLALPVAAPGTAAVPGPTEHRW
                     WEPPPGELPLAEGARRVGEAIAASVRAHVGGLDRISCELSGGLDSTVLAFAARETGPAS
                     LSLLTVAARDRYSEDETWARRAVEVARNTAASTAPVLDHHVIPAADAPYFYADLASTAA
                     ELNDEPLPVAPGRARAELLLGRARATGSRYHLTGYGGDEIFLGLPHAYQDLFHGNPFTA
                     WSHLGGLRHQLGWPLLPTLKALLDRSAFPRWIAGAVTAAPQPVARTPLLSWGVRQSPHP
                     WLTEHARTLIAEEFRAAAEHAEPIDPWRGRHVDIDGVRMGARHFQAMEDIGMTLGLPVA
                     APLYDDRILEATLAVRLPERISPWRYKPLLVEAMRGVVPDALLARTTKDHMSSDEHQGL
                     REHAPEIAELWTGSRLAEHCLVDSLHLLRLAAEPFSPVLVEHSISSTVAGETWLRTAEN
                     AWPTPQSTPTTTPSEASL"
     gene            complement(12749..12880)
                     /locus_tag="DIJ69_RS14415"
                     /old_locus_tag="DIJ69_14415"
     CDS             complement(12749..12880)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010071616.1"
                     /locus_tag="DIJ69_RS14415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14415"
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_104011572.1"
                     /transl_table=11
                     /translation="MKQQKQQKKAYVKPSMFQQGDFSKKTAGYFVGSYKEYWTRRII"
     CDS_motif       complement(12800..12880)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKQQKQQKKAYVKPSMFQQGDFSKKTA"
                     /locus_tag="DIJ69_RS14415_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(12749..12799)
                     /prepeptide="core"
                     /locus_tag="DIJ69_RS14415_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-1.40"
                     /molecular_weight="2020.3"
                     /monoisotopic_mass="2019.0"
                     /core_sequence="GYFVGSYKEYWTRRII"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKQQKQQKKAYVKPSMFQQGDFSKKTA"
                     /leader_location="[12799:12880](-)"
     misc_feature    complement(13156..13171)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.92"
                     /tool="antismash"
     gene            complement(13439..13948)
                     /locus_tag="DIJ69_RS14420"
                     /old_locus_tag="DIJ69_14420"
     CDS             complement(13439..13948)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610344.1"
                     /locus_tag="DIJ69_RS14420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14420"
                     /product="hypothetical protein"
                     /protein_id="WP_044376711.1"
                     /transl_table=11
                     /translation="MSVNATGRTGGRGRLEGVALVVGGALLFALGLLVVVTGTGLSGAL
                     GMRVETFGRIDCHDTRTEKGQTVWHCFGESAAQQRANAAERDRVGREVLRAHVDGVPRS
                     AEISRSRLLFTDHDGRTDPATVTATQVFDGGRWYAHSSTVVGYGMIPLLLGAGTAAWGG
                     YRLRTT"
     gene            complement(14146..15770)
                     /gene="groL"
                     /locus_tag="DIJ69_RS14425"
                     /old_locus_tag="DIJ69_14425"
                     /pseudo=""
     CDS             complement(14146..15770)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /gene="groL"
                     /gene_functions="other (smcogs) SMCOG1299: chaperonin
                     GroEL"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008713461.1"
                     /locus_tag="DIJ69_RS14425"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES; misfolded
                     proteins enter the barrel where they are refolded when
                     GroES binds; frameshifted; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="DIJ69_14425"
                     /product="chaperonin GroEL"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAKIIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGA
                     PTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLR
                     NVAAGANPMALKRGIEKAVEAVSAALLEQAKDVETKEQIASTASISAADTEIGAKIAEA
                     MDKVGKEGVITVEESQTFGLELELTEGMRFDKGYISAYFATDMERMEASLDDPYILIVN
                     SKIGSVKDLIPLLEKVMQSGKPLLIIAEDVEGEALSTLVVNKIKGTFKSVAVKAPGFGD
                     RRKAMLADIAILTGGTVISEEVGLKLENAGLDLLGRARKVVITKDETTIVDGAGDSDQV
                     QGRVNQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
                     NAKAAVEEGIVAGGGVALLQGPRPSSRSSTSRATRRPAPTP"
     misc_feature    15922..15937
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(15925..15940)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    complement(16009..16024)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(16119..16325)
                     /locus_tag="DIJ69_RS14430"
                     /old_locus_tag="DIJ69_14430"
     CDS             complement(16119..16325)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967346.1"
                     /locus_tag="DIJ69_RS14430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14430"
                     /product="cold-shock protein"
                     /protein_id="WP_003967346.1"
                     /transl_table=11
                     /translation="MAQGTVKWFNAEKGYGFIAVDGGADVFVHYSAIQMDGYRTLEEGQ
                     RVEFEISQGQKGPQADMVKLAVG"
     gene            complement(16769..17047)
                     /locus_tag="DIJ69_RS14435"
                     /old_locus_tag="DIJ69_14435"
     CDS             complement(16769..17047)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265553.1"
                     /locus_tag="DIJ69_RS14435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14435"
                     /product="MoaD/ThiS family protein"
                     /protein_id="WP_006126483.1"
                     /transl_table=11
                     /translation="MSVKVRIPTILRTYTGGQAEVPAEGTKLSEVIESLEKDHPGIAAR
                     VLDDQGKLRRFVNVYVNDDDVRFEGGLDAATPDGAGVSIIPAVAGGC"
     gene            complement(17083..18378)
                     /gene="thrC"
                     /locus_tag="DIJ69_RS14440"
                     /old_locus_tag="DIJ69_14440"
     CDS             complement(17083..18378)
                     /EC_number="4.2.3.1"
                     /GO_function="GO:0004795 - threonine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056010.1"
                     /locus_tag="DIJ69_RS14440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14440"
                     /product="threonine synthase"
                     /protein_id="WP_030815340.1"
                     /sec_met_domain="PALP (E-value: 4.1e-61, bitscore: 205.6,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVQTVAGNATTASPDLGPAAALSCRECGERFELGPLFACASCFG
                     PLEVAYDLPTGSPEELRKRIEAGPDNIWRYAPLLPVPADVAEKPNINPGFTKLVKADNL
                     ARELGVTGGLYVKDDSGNPTHSFKDRVVAIAVEAARAFGFTTLSCSSTGNLAGAVGAAA
                     ARAGLRSCVFIPHDLEQGKVVMAAVYGGELVGIEGNYDDVNRFCSELIGDPLGEGWGFV
                     NVNLRPYYGEGSKTLAYEICEQLGWRLPDQIVIPIASGSQLTKIDKGLQELIKLGLVED
                     KPYKIFGAQAEGCSPVSAAFKAGHDVVRPQKPNTIAKSLAIGNPADGPYVLDIARRTGG
                     AVEDVTDEQVVDAIKLLARTEGIFGETAGGVTLGVTKKLIEAGVIDPTLTTVVVNTGDG
                     LKTLDAVSATSQATATIKPSLDAFRAAGLGTA"
     regulatory      complement(18397..18524)
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(18632..18652)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.9"
                     /tool="antismash"
     gene            18678..19628
                     /locus_tag="DIJ69_RS14445"
                     /old_locus_tag="DIJ69_14445"
     CDS             18678..19628
                     /EC_number="2.4.1.266"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511020.1"
                     /locus_tag="DIJ69_RS14445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14445"
                     /product="glucosyl-3-phosphoglycerate synthase"
                     /protein_id="WP_044376729.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.7e-09,
                     bitscore: 36.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEEVERWLTRRSWSSGDRPLHQLTDARAADPRRTSVSVVLPALN
                     EEATVGAIVAVIRRELMEKIRLVDELVVIDSGSTDATAAVARAAGARVVHRDAILPRIP
                     ALPGKGEVLWRSLLVTSGEIVCFVDADLKDFSADFVSGTVGPLLTDPAVQFVKAMYDRP
                     LGDSAGQGGRVTELVARPLLNLHWPQLAGFVQPLGGEYAVRRSLLERLPFPVGYGVELG
                     LLVDALHTVGLDALGQVDVGVRRHRHQDGQALGRMAAAIYRTAQLRLSRGHLVRPALTQ
                     FERGEDGFVARTHAVDTEERPPMREIAEYAERHAA"
     gene            19775..21166
                     /locus_tag="DIJ69_RS14450"
                     /old_locus_tag="DIJ69_14450"
     CDS             19775..21166
                     /EC_number="2.4.1.15"
                     /GO_function="GO:0003825 - alpha,alpha-trehalose-phosphate
                     synthase (UDP-forming) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018101576.1"
                     /locus_tag="DIJ69_RS14450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14450"
                     /product="trehalose-6-phosphate synthase"
                     /protein_id="WP_044376713.1"
                     /transl_table=11
                     /translation="MVTEHTSSSNAQVLVASNRGPITYTLGEDGTLDAKRGGGGLVSGL
                     SSVDDKLWVCAALGDGDREAVRRGVGEPGVRMLDIDAEVHADAYNGIANSVLWFVHHLL
                     YQTPVEPVFDTEFRRQWAAYETYNRAFAEALAQEAGPGAAVLVQDYHLALVPGMLRELR
                     PDLRIGHFSHTPWAPVDYFRLLPDDIAEQLLRGILGADRAAFLTRRWADAFIGCCTEIL
                     GGTGRTRIGVHGLGADADFLRRRSHEADVDERMAALREQVGEDRKTIVRVDRTELSKNI
                     VRGLHAYRTLLETRPEWRERVVHIAFAYPSRQDLAVYRDYTAAVQSLATEINGEYGTES
                     WTPVVLHVKDDFARSLAAYRLADVALVNPIRDGMNLVAKEVPVVSDHGCALVLSREAGA
                     YEELGEDAIVVNPYDVTGTAEALHEALTMSGDERSGRTKRLAEAATALPPQRWFLDQLE
                     ALRQE"
     gene            complement(21263..22114)
                     /gene="otsB"
                     /locus_tag="DIJ69_RS14455"
                     /old_locus_tag="DIJ69_14455"
     CDS             complement(21263..22114)
                     /EC_number="3.1.3.12"
                     /GO_function="GO:0004805 - trehalose-phosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="otsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958814.1"
                     /locus_tag="DIJ69_RS14455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_14455"
                     /product="trehalose-phosphatase"
                     /protein_id="WP_044376715.1"
                     /transl_table=11
                     /translation="MGSHPERLPNPTTPAGREGLDAVLARPDRAVVALDFDGTLADIVP
                     DPEQARAHPGTVEALAALAPKVAAIAVITGRPAGVAVRYGGFAGVPGLEHLVVLGHYGA
                     ERWDAVTGTVHAPAPHPGVTAVRAELPGVLHEFGAWNGTWIEEKGQAVAVHTRRAQDPQ
                     AVFESLRGPLGELAAKHGLIVEPGRLVLELRPPGMDKGVALAGFVAELDAESVIYAGDD
                     LGDLAAFAAVEKLRSEGPDGIPGLLVCSGSAEVPELAERADLSVPGPAAVVDFLAALAD
                     RL"
     gene            complement(22124..22570)
                     /locus_tag="DIJ69_RS14460"
                     /old_locus_tag="DIJ69_14460"
     CDS             complement(22124..22570)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DIJ69_RS14460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DIJ69_14460"
                     /product="hypothetical protein"
                     /protein_id="WP_052807823.1"
                     /transl_table=11
                     /translation="MILGIALLSTATALANTLVRAASGRRRDVAALRLAGAGVPQVLRL
                     VVAEAVAAVGVGAVLGGVVAAVNLLVVWGALALLGVTSAVVGRGPCPAPSSGPPPSWPR
                     APPSCRPCPPCGPGRSNSPAPVISRPGVSSGVGGSTLVLPPPRA"
ORIGIN
        1 cgtgaacggg gctccggccc gaagctcggg tcccgggatt cgggtgtcgg gatgcgggac
       61 ccggggttcg agcgccttct ttaaccgggc ggtagaaaag ggttgttggg aaaacctgcc
      121 ccacctcccc accccgtcac ggccagccag tatgactaat cgtgacagct tgcggcgcag
      181 cgtaatcgcc gcttacggtg cgagaaccaa acgaccccga cgcggtgtta gagcaccagg
      241 ccggggtctc accgcaagat cgaaacccta gaaagacgat cccgtggcta cacagcacca
      301 tagctccgca ctgcccgccc ccgcagtccc cgccgcgtac ccgatggcca aacccgggta
      361 cggcaaacgc tccgcacccg gccaacaacc gcgaatccgt gatgacttcg ccatgctccc
      421 gacccgtgaa cgctacgtcg ccggattcgt cgaccacctc cccgacggcg ccgccatgag
      481 cgtgaagcag ctcgccaaac agctcccgct ctacgggcag caggccatct ccaccgccct
      541 gaaggccttg tccgtcgccg ggcacctgcg gcgcgtccgg tgcgctgtcg gtgcgggcga
      601 cgaaacccgg tgggtcttcc gcaccttctg gtcccgcacc gcccgcgaca acgagtggtg
      661 gaacacctac ctcgccaccg aagccgccac ccggaccgca gcgcctgtgg agcccccggc
      721 ccccaccgcc gtaccacccc agcgcacccc gccccagccg acggacaccg aaccttcgcc
      781 gcccgcccgg gaggcgatct ccgccgagcg cacgcagacc accgcccttt cccccgccta
      841 cctcgccctc gcccgcctcg gccgcgacga ccaccgcctg ggcctctccg ccgacgactg
      901 caccaccctc gaacccctcg cagcccaatg gctcgaccga ggcgtcacca ccgactacct
      961 caccaacgcc ctcaccgcag gactccccgc ccagatcgac tcccccgtcg gcctgatccg
     1021 ccgccgcctc atcgacaagc tgcccccacg cctgccggcc accgcaagca ccccaaccga
     1081 caccccggcc cccacccgac gcctcctcgt cgaatgcacc gactgcggcc gccccggccc
     1141 acccgaagcc ctccccgacg gcctctgccg cccctgccac cagacccaca ccacccacgg
     1201 caacaccacc ccgcccgacc ccactgaact cgcctccgtc aaagcccata tggccaacct
     1261 ccgcaccctc ctcaaacccg tctgaaggct gtcccgtaaa cgatctccgc ctcagtagcg
     1321 tcgggggtcg tcaggcgtgt acccggcctc ttcatccagt cgtgaccggc tgagaaatgt
     1381 ggttgcggtg aataaggcgt acgcggcagt acttccgcat gagtagaggc gcagaggtca
     1441 tcgtgctcgc ccgctgggcg gacgaggtga tgaaaccgtt ggccgaggac gacccggagc
     1501 ggacgtgggg aggccgcttc gcacccgttc accctggtag agatatcgcc gcccacgcgg
     1561 aggtctccgg agctttggtc ataggtaggg tccggggatg tcgaatcagt cagttgcggc
     1621 gggagtcggt ctcgccggtg tgatggcgca ctgcggtgga aatccggtgg gcgccgtgga
     1681 gcttctggtg ggggcgatag cctccgcgcc gacggctccg gagccctatg cggccctcgc
     1741 ggagctgtgg cagggccgac gttcggacgg cctgaaggag agtctcgaag aggagggctc
     1801 cttgagtgct gtgctggcgc aggcgtactt cctgttcctc gacggggaca tggacgacgc
     1861 ggtgatggcc ctcggttcgg tcacgggtgt gcggcccgac gtcgcgtggg gtgccgcacc
     1921 ctggttcggc gatgcgcggt tcctcggtgc ggtgagtgcc gcggcgctgg ccgaggcgtg
     1981 tctgcggacg ttggactacg gccacgacct ggacaccgac gcgatgcggg agcggttcgc
     2041 gccctggttc catgccctcg acgtggtgtc cgagcgggac cccgtgccgg aatcgctggc
     2101 cgccatggcc cggctccccc gggcctgcgg tcggcacgaa ctgtccttcg ctctgtgcga
     2161 ccgcgccgat gctgtcgatc gggtcatgtg gacggccctc gcgcgagcgg ccacctggcg
     2221 cgtgatgggc gacctggacc aggctgcggc ggccttcgaa ggtgccctgc tcctggagcc
     2281 tgccaactgg tccctctatc tggacctggc ggatgtacgt gccgagcagg gcgacttcgc
     2341 cgcagccgcg agcctcgtcc ggcaagggcc tggaccacga acctcacgaa gtgaccctgc
     2401 gctcggcgag cgccgcctac cggacccgcc tgtccggctc ggccgacgac ctgaaggatc
     2461 tgatcaccct ggcacccgag ctcgccgaca ccgcctaccg gaacctgctg atcgactacg
     2521 cgtgtgcggg gtcgcagctc cctccgggac tggtcgccga ggcccaccgg atccgccgaa
     2581 gctgaacggg actctcgcgc gggtcgtcgt caggacggcc ggctccgtcg cccgggggca
     2641 caccaggggt gaggccatca cacccgcacg acggtcacac cagccggatc acctgcttgc
     2701 cccgcacccc acccgcctcc agcgcgcggt gggcggcggc gatgtccgcc agcggatgga
     2761 ccgtgtcgac gacgggccgc aggtcaccgc gctccacgta ggcggtcagt tcggcgaaca
     2821 ggtcgtgctt cgggttgccg ctgaagaagc ggacccgctg acggccgtgc acggccgagc
     2881 ccaggagata gccgatgctc cggaccggat ggtcgatgtc gaaggcgatg gagaccagtc
     2941 gtccgccggg ggccagccgc gttcgcagca ggcggtgctc ggtgccgacg gtgtccatga
     3001 tgacgtcgta gcggtccagt tcggccaggg gcgtggtccg gtggtccagt acctcgtccg
     3061 cacccaactc ccgtacgaag tcggagttct tcacgctcgc gaggccggtg acgtgggccc
     3121 cgagtgcctt gccgagctgg acggcgacac tgccgacgcc gccggacgcc ccgcggacga
     3181 gcaggcgctc gcccgcccgg agtccggcct tgtcgcgcag ggcggtgagg gacgtggtgc
     3241 ccccggcggg cagcgaggca gcctcggtca gggtgacgtt ctcgggggcg tacgcgatct
     3301 ggcggggccg gaccgagacg tactccgccg cgctgccgaa ggaggagcgc cccagaatgc
     3361 cccacacccg gtcgccggtc cgcagcccgg tgaccgaggc gtccacctcg gcgacctcac
     3421 cggcgaagtc gagcccggtc cgctgcggga agcgccggcc ggtgaccagg cggactttcc
     3481 cggcacgccc gtacagctcc ccgccgttga cgctcgccgc atgaacccgg acgagcacct
     3541 cgcccggctt gcggaccggt accgggaccc ggccctcgta gaggacctcg ggcggcccgt
     3601 agctgtcgtg gagcgcggcg cgcatgtcgt tcacggcggg gggtcctgtc tgttccgtcg
     3661 atgtcgatac ggggtgagtg ctgctcccgg tccacggtag gcgggtaaac ggacgacccc
     3721 ctccatttag cctaaagtga gagacatgcc tgctcagccc tctcacaacc cgaccccggc
     3781 caccccggac cccggccccg aggccctgcg ggcggacgcc cgggagaacc gggagcggat
     3841 cctgcgggcc gcccgcgagg cgtacgcgct gcacggcatc gacgtaccga tcagcgccat
     3901 cgcacggcgg gccggcgtcg gcgtcgccac cctctaccgc cgcttcccca cccgtacctc
     3961 actgatcacc gaggcgttca ccgagcagct caccgaatgc gcgggcgcgc tggacgaggc
     4021 tctggaggac ccggacccgt ggcgcggctt ctgcacggtg gtccggaagg tgtgcgcgat
     4081 gcaggccgcc gatcggggat tcacgcacgc gttcctggcc cggttcccgg gtgacacggc
     4141 gtacgccggg gagctcgacc gggcggagga ggggctggcc ctgctggtcc ggcgggcgaa
     4201 ggaggcgggc gcactgcgcc cggacttcga cgtctcggac gtggtgctgg ccatgctggc
     4261 caacaacggc gtggcgaacg gggcgggccc ggagtccgcc gcggcgtccc gacgcctggt
     4321 gggctacctg ctggagtcgt tccgggccgg ccccgccacc ggcccgctcc cgccgcccgc
     4381 ggagctggag ttggaccggt tgggcgggac ggggtgaggg gggcggagga gagggagtgt
     4441 gcgggcccgc gcatgcgagg ggcatcccgc ccgcagaccg cccggctcgc cccctgactc
     4501 aggcgagggc cgtgaccagc gaggcgaagg cggcgatgag gatggccacg cgggcgtagt
     4561 ggtagcggtc ccagcggttc atctgctcct tccagtcctc gggccggttc tccggggtcc
     4621 acgtcttgcc ccggttgttg atcgggacga gcagcaggag cgacatgacc acgctgagga
     4681 gcagcagccc acccgcggcg acgaccaggc cgacacctcc ctccccccaa ccggccacgg
     4741 cccagatcgc gctcaggacg agcgagccga tgtaccagaa cggcatcagc gcccccagca
     4801 tccggccccc gtggcttcgg ccgagctgcg cgctgtcgtc ggggagcgcg tcgaggatcc
     4861 ggttgatgac gaaggcgacg gagaactcca cccccaccag cagtccgacg atcacggtgg
     4921 tgacgatctc aagtgcgtcg agcatgatga cccctcctga aatctagcgg cgctagagga
     4981 tggggcaacg ctaactctac tgccgctcga ttgtctagcg gtgctagaat cgatccatgt
     5041 cggtacagga acgcaaggaa cgggaacggg cgagccgcga gcgcctcatc gtggcgacgg
     5101 cccgcgaact cgccgagcag cagggctggg acgcggtcac cacgcgccgg ctcgccgagc
     5161 gcatcgaata cagccagccc gtcctctaca gccacttccg cggcaagcgc gagatcatcg
     5221 gcgccgtcgc cctcgaaggc gccgccgaga tggccgcggt gctgcgggcc gccgcctccg
     5281 gcgcggacgg ccgccgcgcc cgggtcgccg ccctcgccca cgcctacctg gagttcgccg
     5341 agcggaaccc ggcggtctac gacgccctgt tccagctcga cggcgggctg gccttcgcgc
     5401 aggaggacac cccggagccg ctgaaggacg ccttcgccgc gctgctggag acgctcggcg
     5461 aggtcgccgg ggaaggcgta cacccggcgc tgttcaccga gctcttctgg tccgccctgc
     5521 acgggctggc caccctgacc cgggcggggc ggctcctgcc ggagggcgcc gagcagcggc
     5581 tggatctcct ggtggagcgg ctcgccgtgc tctgacacgt acacgtgctc ccgctgcccg
     5641 ccacgcctcg acagggaccg gtcgggaaac cggtccccac ctcctcaccc cgcccatctc
     5701 cccgtcagga acgtcagcgc gacgagcgtc gtcaccggcg ccgccaagca caggtacacc
     5761 gtcctgaacc acggccgacg caggctcagc gccgccaggc cgatccacag cggccaccac
     5821 agcagcgtcg cgcgcgggac ggacgtgtac cagtacgagg ttcccaacgc ccacaggctc
     5881 agggccacgt acaccgcttc cggccagcgg cggcggcgca ccagccacgc caccagggcc
     5941 agacccacca gcatcgccgc caactccgcc tggaacatga acgcgtagcc ggtcgactgc
     6001 gtgccgccga acgccccggt ccaggtgttc gcccacgcct cccacggggt gtggaacgtg
     6061 cggtaccaac cgcgttcctg cgcgtgcttc caggccatcc agtcgccggt gtgcgcgtgc
     6121 agataccagc tgtacgcggc cgggggcagc gccggcagca gcgtccagcc cgccgatcgc
     6181 caggtccgcc ggcccccgcc cgcacggacg gacagcagga acagcagccc gatcgccgcc
     6241 gcgaggaaca ggccgctgac gcgcaccgcc gtccccagcg tcgtcagtac ggcggcgagc
     6301 gcccaccggt gcttcatcgc cgcgagccag gcgggcaggg cgaacgcgag gaacagcgcc
     6361 tccgtgtaac ccgccgccag gaacaccgcg cagggcgaga gcaggaagag gacgaccgta
     6421 cggtgacccg ccccctcctc cggcagatac gtccgcgcga tccgggccag ggccagcacg
     6481 gcaacggccc ccgcgaccga cgagatcagc agcccggccg ccgtccagtc cggtacgacc
     6541 gtgtgcacgg cacggaggag gaaggggtag ccggggaaga acgcctcccg gttgtcccag
     6601 ccgctcgtcc acggccccgc gcccgccggg aagtagccgt cgcgcgctat gtggaggtag
     6661 tggttcgcgt cccagtgctg gaagggcgcc aggaccgggg ccgtctcccg tacgccggac
     6721 tgcgcgggaa acatccagcg ggcgaagtgg gccgtgatcc acagggacat acgggtcagg
     6781 aggtagagcc acaggacatc gcgatcggcg ggactcaggc ggaaccgcgc cgcccggggc
     6841 tcgggtgcgg cggggaccgg gggacgcaca ggggacggcc gcagcccggg ggagagcgtg
     6901 gacaacgcag gcacctttcg ggcacgcctc gcgggtacgt cggggcgcgc cggatcgccc
     6961 gggaagccgc cggggcacgg aagggaaagg agaagggtgg ggggccgcgc ggcttcaggg
     7021 cgtcgacgcg cccccgtcag tcgtcgccga agccgtcggt ggcgtcgtgt tcgtgctcgt
     7081 actcgtactc gtactcgtac tcgtccgtgt gggtgtgggc gggccgcccg gctcggtggt
     7141 ccggcccgac ggcccctccg accccgcgct ccccggcatc gtggtgctcg gcgacggcgg
     7201 cggggagggc ggctccgtgg gcaggccctc cgacggagcg ggcgacgggt agctgggcga
     7261 cgggctcgtg gccggggcca ccggctccgg ccgcaccggc agcaggccca ccgcgaccgc
     7321 gccgcccccg ccgacgacca ggcacacccc caccgcgacc acggccatcc ggcgtcgctg
     7381 ggcgcgcatg ccgcgccggg tgatgcccga cgcggtctcc ggggcggtca gggcctgccc
     7441 gaactccccg gcctcccgga acagagaccg caacggatcc tgcggctccc tcgggtcctg
     7501 cggttcagac atcaggagcc tcctcgatgc gggggtcccg cagacggtgg gcgagcgccg
     7561 cccgtccacg gaccagatgc gtcttgatcg tgctggtgga aagcccggtc tccccggcga
     7621 tctgctcgac cgtgagatcg cacaggtagt gcagggtcag cgtccgccgc tgctgggcgg
     7681 gcagctcccg cagcgcgtcg accaggacca catggtccgg atccggtggc gcgacgtgct
     7741 ccgccgcacc gctcccccgg ccccaggcgt ccgccgaccg ccgccggaag cgccaacggc
     7801 tcaccgccag ccgccaggcg acggtacgga tccacgcctc gggctgcccg tcccgctcca
     7861 gccgcccccg ccggacccac gccttgacga acgcttcctg cacgacgtcc tgcgcctcct
     7921 ggaggtcgcc ggtcatcacg tacaactggc cggtgaggcg tgcgaccgcc tgtgcgtaga
     7981 actcttcgaa ctcctcgacg gtcaaaagtt gctcccggat ctttcgcttc accgggtata
     8041 cgcccgccgc gggccatccg gtcgacacca cccacgaaga ttcgagggtg acggtcgtca
     8101 cagaccctcg gcgctcagcc gaccacagct cccaggcccc ggcgctgggc ctgccggggc
     8161 ccgcaactgg ttcggaccgg cgccgacccg gccgtacgcc tacgcccctt cgccgtccgc
     8221 cgccagttgc gtcgtcgcca gctcgcggta cagctcgtcc ccggcgatca gctcctcgtg
     8281 cgtgcccgcc gtgcggaccc ggccctcctc caggaccacg atgcggtccg cgtgccggac
     8341 ggtggacagg cggtgcgcga tcaccagcac cgtggtccgc tcggccagtt cgaggatcac
     8401 atcgcgcaac gcctgctcgt tgaccgcgtc caactgcgag gtcacctcgt cgaggaggag
     8461 cagccggggg tggcgcagca gggcccgggc gatggcgatg cgctggcgtt cgccgccgga
     8521 gagggtgacg ccccggtggc cgaccgccgt gtccaggccc tcgggcagcc gctcgaccag
     8581 ggcgtccagc cgggtacggg tcaccgcgga cgccagctcc ttctcgtccg cgtccggggc
     8641 cgcgaagagg aggttctccc gcagcgtccc ggcgagcacc ggcgcgtcct gttccacgta
     8701 cgccagcgag ccccgcagtt cggccagcgg ccagtcccgg atgtcccggc cgcccacggt
     8761 gatcgtgccg gcctcgtggt cgtagaagcg ttccagcagg ctgaacaccg tcgacttgcc
     8821 cgccccggac gggcccacca gcgccaccat cccgcccgtc ggcacgtcga acgtcacccc
     8881 ctggtgggcg ggggcgcgct cgtccccgta cccgaaggtc acgtcctgga aggtcacccc
     8941 gagcgggccg ccgttcctct tcgtcaaccc gcttgattcc tgcgccggtt cgcccggcag
     9001 cgataccacc tcgtcgatcc ggcgcaccgc cgccagcccg ctctgcaggc ccgtccagcc
     9061 ctcgaccaga ccgccgatcg ggcccatcag gtagaagagg tagagcagga acgcgatcag
     9121 ggaggagatc tccagcgagc cggaggcgac ccgcgcgccg ccgacgccca gcaccgccag
     9181 gaacgcgagc tggatcgaca tcgtcatcgt gacctcggtg accgaggacc acttcgccac
     9241 cgtgacgccc cggtcgtgcg catgccgcgc cgccgccgcg acggccgccg tctcccgctc
     9301 ctccgccccg ctcgccttga ccgtgcggaa cgcctggagc acccggtcca gggccgcgcc
     9361 catcgcgccc acggactcct gcgccttgag ctgcgcccgc tggatgcgcg gcatcagcag
     9421 ggatgtcacg gccccgatgc cgacgaccac caccagcgtc acgccgagca gcgtcaggtc
     9481 catgtacgcc atgagggcga tggtgcccag cagcatcagc acgctgttga acgactcgac
     9541 gagcccgctc gacagcaccg tacggagcag ggtcgtgtcg ctcgtgaccc gtgactggag
     9601 gtctccgggg gtcagccggt ccaccgccgg gaccttcaac cgcatgatgc ggccgaccag
     9661 ttggtcgcgt gcgcgcagga ccactccctc tccggtacgg gacatgagaa agctcccgta
     9721 cgcggagagg caggctcctg ccagcacgag cgcggtcagc gcgacgagcg gcgccacggg
     9781 cgagcggccg tcggcgaacg tgtccaccgc gtgcttcgcc atcagcggca tcgccagacc
     9841 cgccccggac ccggcgagcg agagcaggcc cgcccggatc aggacgcccc ggtgcggacg
     9901 gacccgggcg aggagcaggc ggagggggga cacagagggg gaggccgggg tggggcgggc
     9961 cgggtccggg ggtgtcgccg ggccgggcgg ttccgtgttc tcaggcggtc tgcccggacc
    10021 ctgacccgcc tgtcccggct ccgccgtcgt ccccgccacc gcgctcaccc tgaaccccct
    10081 cgcgtaccgt caccaccatc aaaggacgca gatcggcggc ctctgcctgc tccccgaccg
    10141 tacgtccttc cgccagcacc caggcgtgcg gcgagaacgg cggggtcgcc cacacccccg
    10201 cgcaccagtc gggccagaca ccggacatcc ggcaggccag ggcgacggcc accgagcggg
    10261 gcaggcagcc gtaacggctc gcgcagcggc ggctggtggc gacgaccgcc tccagtacct
    10321 ccagcgtctc ggcgtacgag gccgggcgcg cgccccgtga gcaccgggcc agcacccggc
    10381 gcagtcggcc gggcttgagc cgggccagga cgaacgcggc ggcgacggcg gcccgcaggc
    10441 gcaccccgcc cgctcccgcg ccccggcgcg gcatcgtcat ctcggtggtc atgggcgcag
    10501 gatcttcgcc tcgacgagcc gacgggtcag ctccgcgacg tccgactcgg cctcggcccg
    10561 ctcgacgtcg aactcggcga cgatccggtc gacggcggcc tcgggggcgc ggccggccgc
    10621 gagggtctcg acgacgatga cgctggtgtc gttcaactgc cagtagctgc cgctcttctc
    10681 gtcgagcagg acgccgccgt actcggtggt cgtgacggcg atgccttttc tgagcttcac
    10741 agggatgcct cgctgggggt ggtcgtgggg gtcgactggg gtgtgggcca ggcgttctcg
    10801 gccgtgcgga gccaggtctc cccggccacg gtggagctga tggagtgttc gaccaggacc
    10861 ggcgagaagg gttcggcggc cagccggagc agatggaggg agtccaccag gcagtgttcg
    10921 gcgagacggg atccggtcca caactcggcg atctccgggg cgtgttcgcg caggccctgg
    10981 tgttcgtcgg aggacatgtg gtccttcgtc gtccgggcca ggagcgcgtc gggcaccacc
    11041 ccgcgcatcg cctcgacgag cagcggcttg tagcgccagg ggctgatgcg ctccgggagg
    11101 cgtacggcga gggtcgcctc caggatccgg tcgtcgtaga ggggcgcggc gaccggcagc
    11161 ccgagggtca tgccgatgtc ctccatcgcc tggaagtgcc gggcgcccat ccgtacaccg
    11221 tcgatgtcga cgtgccgtcc ccgccacggg tcgatcggtt cggcgtgctc ggcggcggcc
    11281 cggaactcct cggcgatcag ggtcctggcg tgctcggtga gccaggggtg cggggactgc
    11341 cgtacgcccc aggagagcag cggagtccgg gcgacgggct gcggcgcggc ggtgaccgcc
    11401 ccggcgatcc agcgggggaa cgccgaacgg tcgagcaggg ccttcaacgt cggcaggagc
    11461 ggccagccga gctggtggcg caggccgccg aggtggctcc aggcggtgaa cgggttgccg
    11521 tggaagaggt cctggtaggc gtggggcagg ccgaggaaga tctcgtcgcc gccgtagccg
    11581 gtgaggtggt agcgggagcc ggtggcccgg gcgcggccga ggagcagttc cgcacgggcc
    11641 cggccggggg cgacggggag cggttcgtcg ttcaactcgg ctgcggtgga ggcgagatcg
    11701 gcgtagaagt aaggggcgtc ggcggcgggg atgacgtggt ggtccaggac gggggcggtg
    11761 ctcgcggccg tgttccgtgc cacctcgacc gctctgcgcg cccaggtctc gtcctcgctg
    11821 tagcggtctc gggcggccac cgtcagcagg gacagcgacg cggggccggt ctcccgggcg
    11881 gcgaaggcga ggacggtgga gtccaggccg ccggagagct cgcagctgat ccggtccagg
    11941 ccgccgacat gggcccgcac ggaggccgcg atggcctccc cgaccctgcg ggccccttcc
    12001 gccaggggca gttccccggg tggcggctcc caccagcggt gttccgtggg accggggacg
    12061 gcggccgtgc ccggtgctgc gacgggcagg gccagaccgt acccggcacc ggtctcgtgg
    12121 acgccccgcc acacggggcg gcggctcagg gggtgcggca ggaagtccag cagccggagc
    12181 gccagcgcgc tgtcgtccag gggcgcgccg gtcaggcggg ccaggacggc ggggcggtcg
    12241 gaggcgatgg ttccggccgc cgggtgccgg gcgtggtaga tgcggcggag tccggtggcg
    12301 gtgccccgga tccagctgtc cccggacagc cgggcgacca cgtggtagag gccgggcagc
    12361 cgggcgaggc ggcgctccag gccggtcctg tcgcgggcgc cctccaggat cccggcgagc
    12421 acggcgtcgg ggacacggtc cgggccgatg aggacgaggg cgtcctcgcc ccgcgcgaga
    12481 tggctgacct cgcggaccag cgggcgggcg acgacccagg gccggcccga gggatgggcg
    12541 acggtcaggg tgccgtccac ctcccgggcg ggcccggtgg cgtccggcgc ggaggaccgg
    12601 ccggcagccg cttccggtac gggaagctgc ccggccactg ccgctcccgc cgcgttgtcc
    12661 ggcaggacga cgaagtagtc acgcaactgg ccgggcatct tcacctttcg gaagttctca
    12721 cgcggtgcac aggaatcgga tcggcggatc agatgatgcg ccgggtccag tactccttgt
    12781 acgagccgac gaagtagccg gcggtcttct tcgagaagtc gccctgctgg aacatcgacg
    12841 gcttcacgta agccttcttc tgctgcttct gctgcttcat gacaccttcc cttctgtgcg
    12901 gttgacgacc gttatgccca actggcttct gcataactgg agttattcgt gcgactggtg
    12961 ttcatcatgc gaacaccaga gccatcatgt ccggccgttg aaccggtacg catgattccg
    13021 acttaccgtg cgaagttggc cggatagcgc gagcgtcgag gttcggggcg ggctcgtccg
    13081 ggacacctcg accccgggcc ggtacgaccc tcccgccacc ctgtgcagtc gcacacgacc
    13141 cggaccgggg cgctcggtgg actggaccaa tgactggatg cggccatcgg accgggcggt
    13201 gagctggcac gacggggagc agccgtcggc ggacccggcg aaccagccgg aacgggcccc
    13261 ggacggggct ccgcgaccgc tctaccccag ggatcgcggg cgcgccaccg ccctcggcac
    13321 agtcgcaccg aaacgtgctg ccgtacggga gtggccacgg caagtagtca ttcggccacg
    13381 ccgaccccgc gcaaccgccc ggccaccggc gctcacccgg cccgcatgcg ccccatccct
    13441 acgtcgtgcg cagccggtag ccgccccagg ccgccgtacc cgcgcccagg agcagcggga
    13501 tcatgccgta gccgacgacc gtcgaggagt gggcgtacca gcgtccgccg tcgaacacct
    13561 gcgtcgcggt gaccgtcgcg gggtcggtcc ggccgtcgtg gtcggtgaag aggagcctgc
    13621 tgcggctgat ctccgcggac cggggcacac cgtccacatg ggcgcgcagc acctcgcggc
    13681 ccacccggtc gcgctcggcc gcgttggcgc gctgctgggc cgcgctctcg ccgaagcagt
    13741 gccagaccgt ctggcccttc tcggtgcggg tgtcgtggca gtcgatccgg ccgaaggtct
    13801 ccacccgcat gccgagggcg ccggagaggc ccgtcccggt caccacgacg agcagcccca
    13861 gcgcgaacag cagggcgccg cccacgacga gcgcgacccc ctccagccgc cctcgtccgc
    13921 ccgttctccc cgtagcgttc acgctcatgc ccgccccgcc ccgcccccgt atccgtacgc
    13981 ccgtgtccgt acgaccgccc ctcgcgccat tgtcccaagg aacccggaca cgcccaggga
    14041 ccccggacac gccacagggg cggcacctcc gtgaaggaga taccgcccct gtgggacgta
    14101 cgccgaactt cgatcaggtg gggaggccgg ggcctccgtg gctgatcaga agtccatgtc
    14161 accgcccggc atgccgcccg gagcggccgc gccggccttc tcgggcttgt cggcgatgac
    14221 ggcctcggtg gtgaggaaca gcgcggcgat ggacgcggcg ttctgcaggg cggagcgcgt
    14281 gaccttcgcc gggtcgagga tgccctcggc gatcatgtcg acgtactcgc cggtcgcggc
    14341 gttgaggccg tgaccgatcg gcaggttgcg gaccttctcc acgacgacgc caccctcgag
    14401 accaccgttg acggcgatct gcttgagcgg ggcctccagc gcgagcttca cggcgttggc
    14461 gccggtcgcc tcgtcgcccg tgaggtcgag cttctcgaag acggccgagg gccctggagc
    14521 agagccacgc caccaccggc gacgatgccc tcctcgacgg cggccttggc gttgcgcacc
    14581 gcgtcctcga tgcggtgctt gcgctccttg agctccacct cggtggcggc gccggccttg
    14641 atgacggcca cgccgccggc cagcttcgcg aggcgctcct ggagcttctc gcggtcgtag
    14701 tccgagtcgg agttctcgat ctcggcacgg atctggttga cgcggccctg aacctggtcg
    14761 ctgtcaccgg cgccgtcgac gatcgtcgtc tcgtccttgg tgatgacgac cttgcgggcg
    14821 cggccgagca ggtccaggcc ggcgttctcc agcttgagac cgacctcctc ggagatcacg
    14881 gtgccaccgg tgaggatggc gatgtccgcg agcatggcct tgcggcggtc gccgaagccc
    14941 ggggccttga cggcgacgga cttgaacgtg cccttgatct tgttgacgac cagggtggag
    15001 agcgcctcgc cctcgacgtc ctcggcgatg atcagcaggg gcttgcccga ctgcatgacc
    15061 ttctccagca gcgggatcag gtccttgacg ctgccgatct tcgagttgac gatcaggatg
    15121 tacgggtcgt cgagcgacgc ctccatacgc tccatgtcgg tggcgaagta cgccgagatg
    15181 tagcccttgt cgaagcgcat accctcggtg agctccagct ccagaccgaa ggtctgggac
    15241 tcctcgacgg tgatgacgcc ttccttgccg accttgtcca tcgcctcggc gatcttggcg
    15301 ccgatctcgg tgtcggcggc ggagatggag gcggtcgaag cgatctgctc cttggtctcc
    15361 acgtccttgg cctgctccag cagagcggcg gagacggcct cgacggcctt ctcgataccg
    15421 cgcttgaggg ccatcgggtt ggcgcctgcg gcgacgttgc gcagaccctc gcggacgaga
    15481 gcctgggcga gaacggtggc ggtggtcgta ccgtcgccgg cgacgtcgtc cgtcttcttg
    15541 gcgacctcct tgaccagctc cgcaccgatc ttctcgtacg ggtcctcgag ctcgatctcc
    15601 ttggcgatgg aaacaccatc gttggtgatc gtgggcgcgc cccacttctt ctcgaggacg
    15661 acgttacggc ccttggggcc gagggtgacc ttgacggcgt cggcgagctg gttcatcccg
    15721 cgctcgagac cgcgccgtgc ctcctcgtcg aacgcgatga tcttggccat gtgaagtggt
    15781 cctcccggac aggggtggat ttctccggac cgggaggcgc ccgcgacgga cggcctgcgc
    15841 gtgtgccggt tccttgcccc agcacacctg cgggcctcac cggcccggtc caagttctgt
    15901 cactctcacc tggagagtgc taacgccaat gattagcact cgacccccga gagtgcaagc
    15961 gccttcggcg agtgcccgcc atgcggccga ggcgcgcgaa gccctgccgg gaccgggccg
    16021 tgacccaccc tcccccgcac gcacgtaggg cccgaccccc tgatcccggg gtcgggccct
    16081 acgtgcgtga gtggtgtcgt cggacgaccg cgccgagctc agccgacggc gagcttgacc
    16141 atgtcggcct ggggcccctt ctggccctgc gagatctcga attcaactcg ctgaccctct
    16201 tcgagggtgc ggtacccgtc catctggatc gcgctgtagt ggacgaaaac atccgcacca
    16261 ccgtcgaccg cgatgaagcc gtaccccttc tccgcgttga accacttgac ggtgccctga
    16321 gccatgccta actcccctat tactggccct tgcgcaggac cgcacttcgc ggccccgggt
    16381 cgtgactcac cctccgacag gagagggtgc gcggcgccgc agcgcgtcga ccgcggccga
    16441 atgtatccgt ccaactgccc tctgcaacag gtcaatcgga cgagaattct gggcacagag
    16501 gaacaggcga aaatgcgggt ttgctgagat ttacgggcaa gtcgggccag gcaaagggca
    16561 cttatgccgc aagaggttca cgcactttgg ctgcttctta tcggggccgg gcgcattctc
    16621 atatgcgggc ggcacgagca gcggatgggg cttccccaac tgtaccgcgc tcaaccatgc
    16681 agaattgccc cctccgcttc tctcgcggag ggggcaaccg tggtcacaca gaggtgcggt
    16741 ggggccgccg acgagcggcc cgggcggttc agcagccgcc ggccaccgcg gggatgatcg
    16801 agacgcccgc gccgtccggc gtggccgcgt ccaggccgcc ctcgaagcgc acgtcgtcgt
    16861 cgttgacgta cacgttcacg aagcggcgca gcttgccctg gtcgtccagg acgcgggcgg
    16921 cgatgcccgg gtggtccttc tccagggact cgatgacctc ggagagcttc gtaccctccg
    16981 ccggcacctc ggcctggccg cccgtgtacg tacggaggat ggtggggatg cggaccttga
    17041 cgctcatggt ggtgcccttc ttccttcggt acggggtggt cgtcaggcgg tgccgaggcc
    17101 cgcggcgcgg aacgcgtcca ggctcggctt gatggtggcc gtggcctgcg aggtggcgga
    17161 gaccgcgtcg agcgtcttga ggccgtcacc ggtgttgacg acgacggtgg tgagcgtcgg
    17221 gtcgatgaca ccggcctcga tgagcttctt cgtcacgccg agcgtcaccc cgcccgccgt
    17281 ctcgccgaag atgccctcgg tgcgggccag cagcttgatc gcgtcgacga cctgctcgtc
    17341 ggtgacgtcc tccaccgcgc cgccggtgcg ccgggcgatg tcgaggacgt aggggccgtc
    17401 ggccgggttg ccgatggcca gcgacttggc gatggtgttc ggcttctggg gccgtacgac
    17461 gtcgtgaccg gccttgaagg cggcggagac cggggagcag ccctcggcct gggcgccgaa
    17521 gatcttgtac ggcttgtcct cgacgaggcc cagcttgatc agctcctgga gacccttgtc
    17581 gatcttcgtg agctgcgagc cggacgcgat cgggatgacg atctggtcgg gcagccgcca
    17641 gccgagctgc tcgcagatct cgtacgccag cgtcttggag ccctcgccgt agtacgggcg
    17701 gaggttgacg ttgacgaagc cccagccctc gccgagcggg tcgccgatga gctccgagca
    17761 gaagcggttg acgtcgtcgt aattgccctc gatgccgacc agttcaccgc cgtacaccgc
    17821 ggccatgacg accttgccct gctccaggtc gtgcgggatg aacacgcagg agcgcagtcc
    17881 ggcgcgggcg gcggcggcgc cgacggctcc ggccaggttg cccgtggagg agcaggagag
    17941 ggtggtgaaa ccgaaggcgc gggcggcctc gacggcgatc gcgacgacac ggtccttgaa
    18001 ggagtgcgtc gggttgccgg agtcgtcctt cacgtacagg ccgccggtga cgcccagctc
    18061 acgggcgagg ttgtcggcct tgaccagctt ggtgaaaccg gggttgatgt tgggcttctc
    18121 cgcgacgtcc gcgggcaccg gcagcagcgg tgcgtagcgc cagatgttgt ccggaccggc
    18181 ctcgatgcgc ttgcgcagct cctcgggcga gccggtgggc aggtcgtagg ccacttcgag
    18241 cggcccgaaa caggacgcac aggcgaaaag cgggccgagc tcgaaacgct cgccgcactc
    18301 gcggcaggaa agcgccgctg cgggacccag gtccggggaa gcggtcgtgg cattacctgc
    18361 gacggtctga acagccatga tggcggaggc cctttctcct catcttcctc gcgacgcatt
    18421 tcgccgcaag acggaattgg caccttcccc accgtgacct cgcggtcggc aggagggttg
    18481 ccgggacttc aacgggccgt tccctcagtc cctctggatg agctctatgg cactggatct
    18541 tcgatccagg cgtttatgtg cggtccgacc ccgacatgcg acggtcatcc gcgttgttca
    18601 agactgtaac cgaagcaccg gaccgttgag atagtcgtcc gaaccgcgag atggatcaca
    18661 cacagggagt gccgaccgtg ctcgaagagg tggaacgctg gctgaccagg cgttcctggt
    18721 cgtccggcga ccgcccgctg caccagctca ccgacgcccg ggccgccgac ccgcgccgca
    18781 cgtccgtgag cgtggtgctg cccgcgctga acgaggaggc cacggtcggc gcgatcgtgg
    18841 cggtgatccg ccgcgagctg atggagaaga tccggctcgt cgacgaactc gtggtgatcg
    18901 actccggctc caccgacgcc acagcggccg tggcccgggc ggcgggcgcg cgtgtggtcc
    18961 accgggacgc gatcctgccc cggatcccgg ccctgcccgg caagggtgag gtgctgtggc
    19021 gctcactcct ggtgaccagc ggcgagatcg tctgcttcgt ggacgccgac ctgaaggact
    19081 tctcggcgga cttcgtctcg gggacggtcg gcccgctgct caccgacccc gccgtccagt
    19141 tcgtcaaggc gatgtacgac cgcccgctcg gcgacagcgc aggccagggc ggccgggtca
    19201 ctgaactggt ggcacgcccg ctgctcaatc tgcactggcc gcagctggcc ggtttcgtgc
    19261 agcctctggg cggcgagtac gcggtgcgcc ggtccctgct ggagcggcta ccgttcccgg
    19321 tcggttacgg agtggagctg gggctgctcg tggacgccct gcacacggtg ggcctggacg
    19381 cgctgggcca ggtggacgtg ggggtgcggc gccaccgcca ccaggacggt caggcgctgg
    19441 gccggatggc ggcggcgatc taccgcacgg cacagctgcg gctctcccgg ggccatctgg
    19501 tgcggccggc gctgacccag ttcgagcgcg gcgaggacgg cttcgtggcg cgcacccatg
    19561 cggtggacac ggaggagcgt ccgccgatgc gggagatcgc ggagtacgcg gagcgccacg
    19621 cggcgtgagg gggtgggcgg cggccgtgcg gggcgggcac gcggtgtgcg gggctgggcg
    19681 gcgggccgtg cggggcgggc gcgcggtgtg cgggcggtga ccggtcctcc ggacgcgcgt
    19741 ttggcggctt cccgaacggg ctaggttccg ctacatggtc accgagcaca cgtcttcctc
    19801 gaacgcccag gtcctcgtcg cgtccaaccg cggcccgatc acgtacacac tcggcgagga
    19861 cgggacgctc gacgccaagc gcggcggcgg cggtctcgtc tccgggctga gctccgtcga
    19921 cgacaagctg tgggtctgcg cggccctcgg cgacggcgac cgggaggcgg tgcggcgcgg
    19981 agtcggcgag ccgggcgtcc ggatgctcga catcgacgcc gaggtgcacg ccgacgcgta
    20041 caacggcatc gcgaactccg tgctgtggtt cgtccaccac ctgctctacc agacccccgt
    20101 cgagccggtc ttcgacacgg agttccggcg gcagtgggcg gcgtacgaga cgtacaaccg
    20161 ggccttcgcc gaggcgctgg cccaggaggc ggggccgggg gcggcggtcc tcgtgcagga
    20221 ctaccacctc gccctggtcc ccggcatgct ccgcgaactg cgcccggacc tgaggatcgg
    20281 ccacttctcg cacaccccgt gggcgcccgt cgactacttc cggctgctgc ccgacgacat
    20341 cgcggagcag ttgctgcgcg gcatcctcgg cgcggaccgg gccgcgttcc tgacccggcg
    20401 ctgggcggac gcgttcatcg gctgctgtac ggagatcctc ggcggcacgg gccggaccag
    20461 gatcggggtg cacgggctgg gggccgacgc ggacttcctg cgccgccgct cgcacgaggc
    20521 ggacgtggac gagcggatgg cggcgctgcg cgagcaggtg ggcgaggaca ggaagacgat
    20581 cgtgcgggtg gaccgcaccg agctgtccaa gaacatcgtg cgcggcctgc acgcgtaccg
    20641 cacgctgctg gagacccgcc ccgagtggcg cgagcgcgtc gtccacatcg ccttcgccta
    20701 cccctcccgc caggacctcg ccgtctaccg ggactacacg gcggcggtcc agtcgctggc
    20761 gacagagatc aacggggagt acggcacgga gagctggacc ccggtcgtcc tccacgtcaa
    20821 ggacgacttc gcccgctcgc tggccgccta ccggctggcg gacgtggccc tggtcaaccc
    20881 gatccgcgac ggcatgaacc tggtcgccaa ggaggtcccc gtcgtctcgg accacggctg
    20941 cgcgctggtg ctgtcgcggg aggcgggggc gtacgaggag ctcggcgagg acgcgatcgt
    21001 ggtgaacccg tacgacgtga cgggcacggc ggaggccctg cacgaggcgc tgacgatgag
    21061 cggggacgag cgctcgggcc gcacgaagcg actggcggag gcggcgaccg cgctcccgcc
    21121 gcagcggtgg ttcctggacc agctggaggc gctgcggcag gagtgagatc cctttggagg
    21181 acccctctgg aggcgctgcg gcaggggtga gacccttgtg gctttgccgg cggtccgcca
    21241 ggtccgccgc tccggtggtg acctaaaggc ggtccgccag ggccgccagg aagtccacca
    21301 ccgcggccgg gcccggcacc gacagatcgg cgcgctcggc cagttcgggc acctcggcac
    21361 tgccgctgca caccaggaga ccgggaatgc cgtccgggcc ctcgctgcgc agcttctcca
    21421 ccgcggcgaa cgcggcgagg tccccgaggt catcgcccgc gtagatcacg gactccgcgt
    21481 ccagctccgc gacgaacccg gcgagcgcga cgcccttgtc catgccgggc gggcgcaact
    21541 ccagcaccag acgccccggt tcgacgatca gcccgtgctt cgccgccagc tcaccgaggg
    21601 gcccgcgcag cgactcgaag accgcctgcg ggtcctgggc ccgccgggtg tggacggcga
    21661 cggcctgccc cttctcctcg atccaggtgc cgttccaggc cccgaactcg tgcagtacgc
    21721 cggggagttc ggcgcgtacc gccgtgacgc ccgggtgcgg ggcgggggcg tgcaccgtgc
    21781 cggtcacggc gtcccagcgc tcggccccgt agtgtccgag cacgaccagg tgctccagac
    21841 cggggacgcc cgcgaagccc ccgtagcgca cggcgacgcc cgccgggcgg ccggtgatca
    21901 cggcgatcgc ggcgaccttc ggcgcgagcg cggcgagcgc ctcgacggtg ccggggtggg
    21961 cgcgggcctg ttcggggtcc gggacgatgt cggcgagcgt gccgtcgaag tcgagggcga
    22021 cgaccgcgcg gtccggccgg gcgagtacgg cgtcgagccc ctcgcggccg gccggggtgg
    22081 tcgggttcgg aagacgttcc gggtgactgc ccatggggcg agcctatgcc ctgggcggag
    22141 ggagcacgag cgtgctcccg ccgacgccgc tggacacccc ggggcgactg atcacgggag
    22201 ccggcgagtt cgaccggccg ggtccgcaag gcggacaggg ccggcaggac ggcggagccc
    22261 gcggccagga gggcggcggc cccgacgacg gggccgggca cggcccacgg cccacgacgg
    22321 cggacgtgac gcccagcagc gccagcgcgc cccacacgac cagcaggttc accgcggcga
    22381 ccacgccccc gagcaccgcg cccaccccga ccgccgccac cgcctcggcg acgacgagcc
    22441 gcaggacctg cgggacgccg gccccggcga gacggagcgc ggcgacatcg cggcgccgtc
    22501 cggaggcggc cctgaccagg gtgttggcca gggctgtcgc ggtggagagc agggcgatgc
    22561 cgaggatcat ccgcaggccg gtgcgggtgt ggtcgtcggg accggtgtcg gcaggggcca
    22621 gtcatgccgc gcgggtcgcc acccgcgtac cggtgtcggc agcggcggtg tccagcgcgg
    22681 cggcgacacg cccgcgcc
//
