LOCUS       NZ_CP029361            22910 bp    DNA     linear   CON 31-MAY-2024
DEFINITION  Streptomyces globisporus strain TFH56 chromosome, complete genome.
ACCESSION   NZ_CP029361
VERSION     NZ_CP029361.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces globisporus
  ORGANISM  Streptomyces globisporus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7488586)
  AUTHORS   Cho,G.
  TITLE     Complete genome sequence of Streptomyces globisporus TFH56 isolated
            from tomato flower
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7488586)
  AUTHORS   Cho,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAY-2018) Division of Applied Life Science, Gyeongsang
            National University, Jinjudaero, Jinju 52828, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 29-MAR-2018
            Assembly Method :: canu v. 1.7; arrow polish v. SMRT link 5.1.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 37.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003147545.1-RS_2024_05_31
            Annotation Date                   :: 05/31/2024 02:17:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,917
            CDSs (total)                      :: 6,829
            Genes (coding)                    :: 6,492
            CDSs (with protein)               :: 6,492
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 337
            CDSs (without protein)            :: 337
            Pseudo Genes (ambiguous residues) :: 0 of 337
            Pseudo Genes (frameshifted)       :: 240 of 337
            Pseudo Genes (incomplete)         :: 121 of 337
            Pseudo Genes (internal stop)      :: 7 of 337
            Pseudo Genes (multiple problems)  :: 31 of 337
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:15:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3082834
            Orig. end                         :: 3105744
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029361.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22910
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="17"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22910
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22910
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12910](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12910
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            683..1471
                     /locus_tag="DIJ69_RS13770"
                     /old_locus_tag="DIJ69_13770"
     CDS             683..1471
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061144.1"
                     /locus_tag="DIJ69_RS13770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13770"
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="WP_172593809.1"
                     /transl_table=11
                     /translation="MAQVSIVTSQAGAVIGHDDAMRFLFVGDSMTIGHAGDFTWRYRMW
                     QHLEAFPGLPYEIVGPRSTLYDAEAGAPVSHAYADPSFPPAARRHLSGWGEGWLHMAPV
                     IADAVRETEADVLLVSLGLIDLGFYTDAEQTAANARAFITAARTANPRLRMVLLPVIPN
                     IRAGTDAPFAASCARFNELLAKAVADLDTASSPLLLASRPPGYDIHADTYDGTHPGPSG
                     EHLLAAAFADAMHQAWGLGGPYAGGVTARVPAQAQVSAPV"
     gene            complement(1539..2180)
                     /locus_tag="DIJ69_RS13775"
                     /old_locus_tag="DIJ69_13775"
     CDS             complement(1539..2180)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510865.1"
                     /locus_tag="DIJ69_RS13775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13775"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_030799335.1"
                     /transl_table=11
                     /translation="MADSWTVQRTGPGDAARTQAREQLLEAARELYGVNGYRATAEHDV
                     CEAACVPIEVLRQEYGSREGLLIALHNRVTTTGLRAAESALLTEGIEECSIEERVRRLF
                     DAYVEAVTRDPREARVTFVEVLGVSAVVDEHCKLWRALWTEFLTGEAERAVDRGEAEDR
                     DHRVDVMVMVGTVHELMAHHARRCRRARPGEVSGELTQLALTMLGSQRSG"
     misc_feature    2282..2297
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.77"
                     /tool="antismash"
     misc_feature    2282..2298
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.55"
                     /tool="antismash"
     misc_feature    2298..2313
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.77"
                     /tool="antismash"
     misc_feature    2298..2314
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.55"
                     /tool="antismash"
     misc_feature    2352..2366
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     gene            complement(2370..3149)
                     /locus_tag="DIJ69_RS13780"
                     /old_locus_tag="DIJ69_13780"
     CDS             complement(2370..3149)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510866.1"
                     /locus_tag="DIJ69_RS13780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13780"
                     /product="hypothetical protein"
                     /protein_id="WP_044376380.1"
                     /transl_table=11
                     /translation="MTYTDAEDRSPQLRGALESVIGGYMAGVAEVLLTEEVPVASTSAY
                     GDVHDPSQDDFAGDVEGSVEFTRAFSRRLLGDGGETGLLWCGVSGWCFFHIPEGSGRSL
                     VDSARWMGSGLTPEPVRVAAFLSEVRLDPREAGSGERPFYRAPHSDPDVLLRRLEAFDT
                     ESGPDDVVTRLRDTACRRRIVEALTAEDQEIADVSLHTGELEALTDLLEYVEGTTPDDV
                     LRELARRLTRDLSLRARDGVESVDEHREAFSYAEEQR"
     gene            complement(3289..5571)
                     /locus_tag="DIJ69_RS13785"
                     /old_locus_tag="DIJ69_13785"
     CDS             complement(3289..5571)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450053.1"
                     /locus_tag="DIJ69_RS13785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13785"
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="WP_044376382.1"
                     /transl_table=11
                     /translation="MGPKPPYLDPALPVAERVADLLGRMTLPEKVGQMLQLNAKEGVRH
                     LVEDLHAGSILHASPERVREAAALTAKTRLRIPLLVAEDCIHGHSFWEGATIYPTQLGM
                     AATWDPELVERIARATAVEVAATGVHWTFSPVLCITRDLRWGRVSETFGEDPFLIGELA
                     SAMVRGYQGEGLDDPTAILACAKHFAGYSETQGGRDASEADISRRKLRSWFLPPFERVA
                     KEGCRTFMLGYQSMDGVPITVNNWLLNEVLRGEWGYTGTLVTDWDNVGRMVWEQKVYAD
                     YAQASAAAVRAGNDMVMTTSNFFEGAQEAVAQGALTEVEIDAAVRRILTLKFELGLFEN
                     PRHPDAGRQAEVIGSGAHAALNLEAARRSLVLLANDGTLPFAGGLVADGEGRATGPGPR
                     TVAVIGPNADDAQTQLGDWAGSSGQADWLPDGQPRAMIRTVLDGFRDHVPADWTVSYAP
                     GARILEVGPDPEGEFFPDGQPRPEVVHPAAPDAELIAEAVAAAEAADHVVAVVGDRIEL
                     IGEGKSTATLELVGDQVALLDALAATGKPLVVVVISSKPLVLPPSALGAAAIVYAANPG
                     MLGGRAVAELLLGLIEPTGRLPLSFARHAGQQPTYYNQVRGQHGTRYADLTQRPAFAFG
                     EGLSYSTVAYTDLEVLTAVVDESETVRARVTVTNTGARPALETVQVYVSDTVTSVTWAE
                     KELKAYRQVALAPGESREILFELPVADCTLVDAEGVRRVEPGRFELLVGPSSRDEALLR
                     REFTVKG"
     gene            5733..6332
                     /locus_tag="DIJ69_RS13790"
                     /old_locus_tag="DIJ69_13790"
     CDS             5733..6332
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958676.1"
                     /locus_tag="DIJ69_RS13790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13790"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_030799343.1"
                     /transl_table=11
                     /translation="MTSGTRRGYAKGRAKRTEILDQAMTLFGEAGYRGASLRVIATRCG
                     ISHPGLLHHFPTKEALLLAVLQRRDDVDDEWLALGVTRGVDHLRRLVDLAELNAKRRGI
                     VELFSVVAAEATAPDHPAHAYFEARYRTSVANTERAYLQARESGELRDDVDPSAAAQQL
                     IALMDGLQIQWLISDCTTDMAGVLRAHVRAQLTVEF"
     gene            complement(6355..6693)
                     /locus_tag="DIJ69_RS13795"
                     /old_locus_tag="DIJ69_13795"
     CDS             complement(6355..6693)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061149.1"
                     /locus_tag="DIJ69_RS13795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13795"
                     /product="hypothetical protein"
                     /protein_id="WP_030799345.1"
                     /transl_table=11
                     /translation="MKGARLWKSCVPVAANLLLGIPAIVPAFLIWYVLSNGPLAELGWT
                     QREPTENDGMWPWLVFVVPVVGCFGGLWTLLNLWMRRRLMPAAPPGPYWSVALTLTLTP
                     YLLGVAFG"
     gene            complement(6711..7613)
                     /locus_tag="DIJ69_RS13800"
                     /old_locus_tag="DIJ69_13800"
     CDS             complement(6711..7613)
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967252.1"
                     /locus_tag="DIJ69_RS13800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13800"
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="WP_030799347.1"
                     /sec_met_domain="Abi (E-value: 4.4e-15, bitscore: 54.5,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAPSGSRYDEQGRNGHGGRFGWIGELSAVVGLVLLAVVVVGIVG
                     MVLAELLDATPADPDSDLFFEDPVADLVVQLLGIAIAIPIVLWGARVIGRRPAGTVSSV
                     VGRLRWGWLGRCAAVGFPLMAVQIGVLIAWTWNDEPVGESGTGFPGWPVFLLSLAVILA
                     LVPFQAAAEEYVFRGWLVQVIGRVVRTPWPAVVVASLLFALAHGFGELSGFLLLLYSAL
                     WWGWLVIRTGGLEAVIVMHVANNLLAFGLAAGFGELASTETAADAPWQAMVAELVFAPL
                     YCLTVARIAGRRGIERVSP"
     gene            complement(7869..8501)
                     /locus_tag="DIJ69_RS13810"
                     /old_locus_tag="DIJ69_13810"
     CDS             complement(7869..8501)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061151.1"
                     /locus_tag="DIJ69_RS13810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13810"
                     /product="response regulator transcription factor"
                     /protein_id="WP_030799350.1"
                     /transl_table=11
                     /translation="MAGVITVAVVDDDRMLRDGIRSWFEGVEEVDLVACAATVDELLAG
                     PGKPPDVVLLDLMLRDDRPPADNIRRLRAAGSRVLMISVVADRDRIVAAVTDGADGFLT
                     KDQELSVLVEAVGEIAAGRTAHSPELAFALAYDRGSMRPRLSPQEREVLVGYASGLTLK
                     ATARRAGITVNTAKYYLDRVKAKYQEAGRPTYTKIDLAARVREDGWR"
     gene            complement(8489..9655)
                     /locus_tag="DIJ69_RS34635"
     CDS             complement(8489..9655)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DIJ69_RS34635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_128862430.1"
                     /transl_table=11
                     /translation="MVIATALYRGSHLVAGGAVVTQHQHDRLFPWLALGAAVAATALIW
                     FMAARHRRLVSWAVGLDVLTIGCLLPFGAYAWGGAHAQESIAWVMLLGGSSSAMAAVAF
                     RARLLAVAVVLLVVTHLAGYLLVEADASVTGAHLNALVFSAVVSWVLTWYLCRQGKQVD
                     SANRRALAAEAQRARFAERVAHHNALHDTVLATLTAIARGGVDANTSMMRERCAREAAY
                     LRRLVEQADDREQASEVRAALEESVRAAEALGLRVTARYHEPPAVPGEIALAMARAATE
                     ALNNVRCHAGTGHAFLTAGGDSGRLIVTVVDRGRGFGGGAAGPDGAGASEGAEAPGGAA
                     RPPGPARPGAGGIGLDRSVHARMRGVGGRAFVDSAPGEGVRVELRWPG"
     misc_feature    9649..9663
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.38"
                     /tool="antismash"
     misc_feature    9766..9780
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            10001..12910
                     /gene="lanL"
                     /locus_tag="DIJ69_RS13820"
                     /old_locus_tag="DIJ69_13820"
     CDS             10001..12910
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="DIJ69_RS13820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13820"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_052807799.1"
                     /sec_met_domain="Pkinase (E-value: 5.2e-13, bitscore: 47.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.9e-41, bitscore:
                     139.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHRDEHDSGSFFALDTGLLPGIVEGVLHRRGATQWSVEQGEFW
                     CSVRPHGHRSGEQGWKLHLSATPLSAALVLAVAADVLVEERASFKFAGALDRVALLTGG
                     RADRGGGGKFITVYPDEPELFRRLARRLHAATLGLRGPRILSDRPYAPGSLVHYRYGVF
                     SGVRTTTNDGDTDVRLRRPDGGLEKDRRQAWVTTPAWAPPPFPEPTPSPEAVARSGAVP
                     SRPRQAAGPRKPESGPARKSVRLNGRYVVAKAIRHAFKGGVYLATDETTGRQAVVKEAR
                     AHVGVRMDGTGLQDTLRHEAEMLEALAPLGLTPAAIELFAQGGNLFLAQEFVPGRTLRD
                     RLVEQPVRDLAEFLDLGRQIVEIVAAVHGTGRVLRDLSPNNLMVTPEGRVRLIDVEYLA
                     PEGVPVRRGYTPGYVGPEVSSLRDYDFTPPTYASDLYGLGAVLLHLATGVDMLLVPDDR
                     PVGDRTEALIRSAIADHSWTAPLLPLLLALCSPLPGERWELPRVRKALAELPGSAPRAA
                     DGDGDGDSGSSGDSGRTGGAMTPVADSTGEGGLPALSDEERERLLADGLAYLLRTRPGS
                     GGHLWDVSAFGATTDPLNVQYGSAGVLAVLTRAAAAGAGADVRDGVAELTEWTRRGLAG
                     LPTGRTADGTLLPGLHFGRSGTAWALLDAAMLLGDDSVAAEASALARAVPVDWPNRDIC
                     HGAAGAGMAQLHFWRTTGDPVFRDRAVECAEAIVAAAEDHPAGVIWPVPATFDSNLAGA
                     RHYGFAHGIAGIGAFLLAAGVAAERADLVRAARTAGDTLVRLARTGNGRAVWPAGDRDA
                     DGPVGQTHWCSGSSGIGTFLVRLWAETGDERHREAAVLAAAGVREAMWLSSPAACHGLA
                     GNAEFLLDLYAALGDARFHDQAGQLAACIRTRAVRRDGLLVVPDESLEAVTGGYQTGVA
                     GTVGMLLRLRDGGPRLWMPDTPDLFAPVGRNPRTTVGAR"
     gene            12907..14922
                     /locus_tag="DIJ69_RS13825"
                     /old_locus_tag="DIJ69_13825"
     CDS             12907..14922
                     /NRPS_PKS="Domain: Abhydrolase_1 (406-517). E-value:
                     1.6e-08. Score: 26.4. Matches aSDomain:
                     nrpspksdomains_DIJ69_RS13825_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="DIJ69_RS13825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13825"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_044376387.1"
                     /sec_met_domain="PF00561 (E-value: 1.1e-05, bitscore: 23.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 1e-21, bitscore:
                     76.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRRPERISFRFSARSRFAACLVTTSDGALAPGWWDLDGTRPPYA
                     GDTPRFREGAPTETTATQVLPTECGGLLRLRGAAGSGRHLLLLSHPASAGPVTEETTTA
                     GTPLAGPRGPSSAGTGPEAPAPAEGAAEWLSVEARGLRLVPGGPRGTLALAVETAHDGR
                     TRVWRVRSAPLRLSDPVTLPGRVTALLPLDGTGCRYATDLEGPDGYRPVSLDLRDGNRL
                     ALPSPPDGRIHRLLLSAPASGLLLTASDPGDGRLRIARATLGLRPRLDFPDRLNSLDGA
                     VLPLAADPAGERVALRVSRGAQARLYLYDVAADRPRPAELPPGAFHPVAGWSEGGLRVV
                     YAAPDRPADLVGVPDTAAHGAPATPSGAASPTLDVSATPHAPTEWFATPSGRFEAVRLG
                     DWRTVPTVVVALHGGPEDHWTLGHDPVLARLSETGAAVVAPNQRGSTGYGRAHAEAIHG
                     AWGVPDLADIRALVRTLTEQRPPDAEPPVLLGTSYGGFLALLAVCADPYAWARCAVIAP
                     FLSARGLRERSSAAVRALIDRHGLGEPPDDGLGPRDVERLAHRIRVPLLALHGCDDPVV
                     PVDETRRLRRALTRAGGPERVPHDCLDIAGAGHHPLQERGGAELTDRLVGFLTAGFPDR
                     RRSPAPPGLTVADAAVRHRPSSAVFGHITHDERTPS"
     aSDomain        14125..14457
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DIJ69_RS13825_Abhydrolase_1.1"
                     /evalue="1.60E-08"
                     /label="DIJ69_RS13825_Abhydrolase_1.1"
                     /locus_tag="DIJ69_RS13825"
                     /protein_end="517"
                     /protein_start="406"
                     /score="26.4"
                     /tool="antismash"
                     /translation="VVVALHGGPEDHWTLGHDPVLARLSETGAAVVAPNQRGSTGYGRA
                     HAEAIHGAWGVPDLADIRALVRTLTEQRPPDAEPPVLLGTSYGGFLALLAVCADPYAWA
                     RCAVIAP"
     gene            14919..15050
                     /locus_tag="DIJ69_RS35105"
     CDS             14919..15050
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038157.1"
                     /locus_tag="DIJ69_RS35105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ALQxL family class IV lanthipeptide"
                     /protein_id="WP_189460106.1"
                     /transl_table=11
                     /translation="MIDNTMTVDVDELQTLEGEESVALAGCTRTCTWTCSITSIEQQ"
     CDS_motif       14919..14996
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MIDNTMTVDVDELQTLEGEESVALAG"
                     /locus_tag="DIJ69_RS35105_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       14997..15050
                     /prepeptide="core"
                     /locus_tag="DIJ69_RS35105_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="2.70"
                     /molecular_weight="1835.1"
                     /monoisotopic_mass="1833.8"
                     /core_sequence="CTRTCTWTCSITSIEQQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIDNTMTVDVDELQTLEGEESVALAG"
                     /leader_location="[14918:14996](+)"
                     /alternative_weights="1853.1"
                     /alternative_weights="1871.1"
                     /alternative_weights="1889.1"
                     /alternative_weights="1907.1"
     gene            15190..16947
                     /locus_tag="DIJ69_RS13830"
                     /old_locus_tag="DIJ69_13830"
     CDS             15190..16947
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="DIJ69_RS13830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13830"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_078955688.1"
                     /transl_table=11
                     /translation="MTSPRRLVWDATARTRGWFVLASATAALGAAGTLAFPWAMARALD
                     AVVARRPATGPVLVCAALLALVVTTGALQTLANGGYGSGTVAALRRSMARRALDAGVPG
                     TAGFPAGDLAGRLSAGCAQAGSAGVTLVTASAAVLTSLAGVVALWLIDWRIGLCFSLGV
                     PPLVLIARVFMNRGSGLFLRYQETQGRISALLLEALGGARTIGASGTAAAETRRVLEPL
                     PELSRTGHRVWALQRDTGWQVGLLIPAVEVLVLCAGGLALLHGDISAGELAAVVGYTAL
                     AMAALDQLDALFALGMSAAGARRVAEVVDQPVPAPGTRARPASGPGTVTLSGVTVRSGT
                     RLVLDSVDLVVPAGTALAVVGRSGAGKSTLAALIGRLREPDAGLVAIDGVPLPELTPRA
                     LRAAVGYAFERPALLGTTVAGTIAFARPDASREEVAAAAGAARADDFIARLPHDYDTPL
                     KDAPLSGGEVQRLGIARALVHDPAVVVLDDALSSLDTATEARVGSALASAWSARTRVLI
                     AHRVSTAARADLVAWLENGRVRALGPHQELWRLDGYRALFAAGTGTETETAPEAVPEHD
                     PHPHPQESV"
     gene            16944..18698
                     /locus_tag="DIJ69_RS13835"
                     /old_locus_tag="DIJ69_13835"
     CDS             16944..18698
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946994.1"
                     /locus_tag="DIJ69_RS13835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13835"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_044376390.1"
                     /transl_table=11
                     /translation="MSEAAPRPIDRHLFAGFLRQHRGAAVAVAGWSLLEAVPALASGLL
                     VAAALDRGFLAGRPAEGFFWIGLLGAAMVFRALMTRTLTPWLGRLVEPLRDELVTAVAA
                     GAVHRAAAGVRDAAGAGVARLTVQVETVRALVSALLRSARQLGVSLLMAFVGLAALSAP
                     VAAVTLPPVLLTLLLCAPRLRVLARRQRRQLRAEEGLTAAAGETFDGIRDVVACGAQDR
                     VADDLSARITDHRDAVRAVARAASANTLLVSLGSHLPLLVLLLAAPRLLDRGALSVGEL
                     LGATSYLISGVAPALRSLVAVLGSWGVQLATVLRQLSRSTTQGPHGAAESQGRATSPHT
                     PRSPHLSLVNVGYAYGPGAAPVIDRLSLDIPAGSHLTVVGPSGAGKSTLTTLLAGLAAP
                     DNGRLTLGGVPVTEVDRAWLHRAVTLIPQEAYVFTGTVRDNLRYLRPLAKDADLLASAT
                     AVGARALVDRLGGLDAPVGLDGPPLSSGERQLVALARAHASPASVVLLDEACCHLDPAA
                     EERAERAFAARGTTLVVVAHRISSALRAPRVLVLDGERTAIGTHAQLLDESPLYADLVG
                     HWVAAGTP"
     misc_feature    18717..18732
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.34"
                     /tool="antismash"
     misc_feature    complement(18724..18739)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.19"
                     /tool="antismash"
     gene            18757..19542
                     /locus_tag="DIJ69_RS13840"
                     /old_locus_tag="DIJ69_13840"
     CDS             18757..19542
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126602.1"
                     /locus_tag="DIJ69_RS13840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13840"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_044376393.1"
                     /transl_table=11
                     /translation="MTAQTPHPPIDTSKPHSARVYDALLGGKDNYPVDQQVAELLPVEA
                     KIGAHQQRAFMHRATAWLAGQGVTQFLDIGTGIPTEPNLHQIAQEIRPSARIVYCDNDP
                     IVLRHAEALLVSRPDGVTDYVHADVREPAIILDAARETLDFDRPIALSLLGLLHFLPDA
                     EKPIDIIRTFTDAMAPGSYVVLSHGASDVNEEKGEQSADEYKKGGIQLALRTREEFSRF
                     FEGLEIVTPGLVKAPEWFNGTPAPEQEHSGMYVAVARVP"
     gene            19673..19867
                     /locus_tag="DIJ69_RS13845"
                     /old_locus_tag="DIJ69_13845"
     CDS             19673..19867
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126498.1"
                     /locus_tag="DIJ69_RS13845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13845"
                     /product="hypothetical protein"
                     /protein_id="WP_044376396.1"
                     /transl_table=11
                     /translation="MTHRISALISVFGVFASVLLLALAVREYRSGATVLWLVFGATAFL
                     GAVYALVVDVRRLRTGPTA"
     gene            complement(19945..20379)
                     /locus_tag="DIJ69_RS13850"
                     /old_locus_tag="DIJ69_13850"
     CDS             complement(19945..20379)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958696.1"
                     /locus_tag="DIJ69_RS13850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13850"
                     /product="hypothetical protein"
                     /protein_id="WP_044376422.1"
                     /transl_table=11
                     /translation="MELKNSPDPAPFCPAWIPASGHALRHVGIHFDAVRAIGLLGEEIA
                     YEVMQFTDFQAGPIVRSGIGERSMYFLLAPGTAAEHRWPPGVEAMSRSARGDAFVGVPA
                     LGGGTWPLDRRSRPTAQDPFVDGALLHEMAWLRAGCAVKE"
     misc_feature    20407..20422
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            20462..21289
                     /locus_tag="DIJ69_RS13855"
                     /old_locus_tag="DIJ69_13855"
     CDS             20462..21289
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510895.1"
                     /locus_tag="DIJ69_RS13855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13855"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_078955689.1"
                     /transl_table=11
                     /translation="MHSSDQPESTAEMFGLLLRHFRVLAGLSQDQLGKRIGYSKSQVAM
                     VERGARPPTDVFVQRADEVLRAQGALIVAAPKPPKQTERRNPLPGWFTPFADEEEKAWA
                     RHEYENHVMPGLLQTEAYARAVFTSRYPTYDDDEIEAKVAARLERQKLLSRRPLPDISF
                     VLEMSVLTRPIGGRRVMKAQLHHLAEVARLRHVRIQLMDPDREDHAALDGPFVLLETDK
                     RQQLAYIEGQGGSFFVTEQPELGNLFGKYGVTRAQAYTPERTLEKIEKMAEEL"
     gene            21286..21525
                     /locus_tag="DIJ69_RS13860"
                     /old_locus_tag="DIJ69_13860"
     CDS             21286..21525
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610436.1"
                     /locus_tag="DIJ69_RS13860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13860"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_044376399.1"
                     /transl_table=11
                     /translation="MSTDLHWFKSSYSGSEGGNCVEVALTWSKSTYSGPQGGNCVEVAT
                     CPHTVHIRDSKDLTLTALAVSPDTWTSFVEFAAS"
     gene            complement(21522..22454)
                     /locus_tag="DIJ69_RS13865"
                     /old_locus_tag="DIJ69_13865"
     CDS             complement(21522..22454)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014053673.1"
                     /locus_tag="DIJ69_RS13865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_13865"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_030799375.1"
                     /transl_table=11
                     /translation="MDAEALRTFVAVAETGQFQAAADELGISQQAVSKRIAALERHLGV
                     MLLVRTSRGSRPSPDGQVFLPHAKKILAVVEQAEQAVRPGNRPLRVDVLNRRISPAQAV
                     HRFYRSHPEMELDVVTLSTENAAQAARAVLEGTVDASFRALPADQVPAGISAERLMDAP
                     LELLVGSGHPLADAPHVSPAELAGHRIWIPGIMPGTEWAAFYRTLSEAFGLSIDALGPD
                     FGPEALMDTLAESDSLATLVGRGDRYLWPQAHDLRRIPLRDPTPVYPHVLLFRSGDQHP
                     VLTALRDYLRTAGPRTPQDVWAPEWVEAA"
     misc_feature    complement(22759..22773)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.75"
                     /tool="antismash"
ORIGIN
        1 cgggcgctga agtacgagcg cagcaccagg cgtttcccgt cgggcgagaa ggccccgtcc
       61 gtgacccacg gcacctcgtc cacccgccgg aaggtgttca cggcaccggc ggtcagcttc
      121 gcgggccctt cgtagaggcc cgccgccgtc ctcgttcttg gaggcgatgt agacgcggcc
      181 ggtcttcggg tggaccatca gcgcctcggc gttgcgggcc ccgtcggcgt acttcacgtc
      241 gtactggacg gcgtcgacgg tggcgtcgcg cagctccttc ggctcgggga agcggtagat
      301 ccagacatgg ctccaggtgc cgtcgaggtt gtccccgatg tcaccgacgt agaggtcgcc
      361 gtcgggcccg atggagatgc cctcgacatc gcgcggctcc cccacacccc gcatggtgat
      421 ggtcgcgagg gtcttgcccg tacgggagtc gacggcgaag acgtaggggc cgtcgtcgct
      481 gtcgttgtgc gtccaataga cgccggggtg ggcgcggctg gcggcgaggc cgctggactc
      541 ggtgatacgg gggtcctcga tcgtgaagtc acggtcgggc cgcccgtcgt cggccacggc
      601 cgggccggcc ccggcgaaca gcagaacagc ggcggcgagg gcggcagcac gggtgcccgc
      661 cggcccggtc ggatggaggc gcatggctca agtgtccatc gtcacgtcgc aggccggagc
      721 ggtgatcggc catgatgacg ccatgcgttt cctcttcgtc ggcgattcca tgaccatcgg
      781 gcacgccggc gacttcacct ggcgttaccg gatgtggcag cacctggagg cgttccccgg
      841 tctcccgtac gagatcgtcg gcccgcgctc gacgctgtac gacgccgagg cgggcgcccc
      901 ggtctcccac gcgtacgccg acccgtcctt cccgcccgcc gcccgccgcc atctgtccgg
      961 ctggggcgag ggctggctgc acatggcccc ggtgatcgcg gacgcggtgc gcgagacgga
     1021 ggcggacgtc ctgctggtct cgctgggcct gatagacctc ggcttctaca cggacgccga
     1081 gcagacggcg gcgaacgccc gcgcgttcat cacggcggcg cgcacggcga acccgcgtct
     1141 gcggatggtc ctgctcccgg tgataccgaa catccgggcc gggacggacg cccccttcgc
     1201 cgcctcctgc gcccgcttca acgaactgct ggccaaggcg gtggcggacc tggacaccgc
     1261 gtcctccccc ctcctgctgg cctcgcgtcc gcccggctac gacatccacg cggacacgta
     1321 cgacggcacg caccccggcc cgagcggcga gcacctcctg gcggcggcgt tcgccgacgc
     1381 gatgcaccag gcgtggggcc tgggcggccc gtacgcgggc ggggtcacgg cacgggtacc
     1441 ggcgcaggca caggtctcgg ccccggtctg accctcgtcc gtcaggagtc cggctcggta
     1501 caggccaccg cacccggtac gcctcgaccc ggtggtcctc acccgctccg ctgcgacccc
     1561 agcatcgtca gggccagctg ggtcagttcg cccgagacct cgccggggcg ggcccggcgg
     1621 cagcggcggg cgtggtgggc catcagctcg tggaccgtgc cgaccatcac catcacgtcg
     1681 acccggtggt cccggtcctc cgcctcaccc cggtccaccg cccgctcggc ctcccccgtg
     1741 aggaactccg tccacagcgc ccgccagagc ttgcagtgct cgtcgaccac ggcgctcacg
     1801 cccagcactt cgacgaacgt cacgcgggcc tcgcgcgggt cgcgggtgac ggcttccacg
     1861 tacgcgtcga agagcctccg gacccgctcc tcgatcgagc actcctcgat gccctcggtc
     1921 agcagggcgc tctccgccgc ccgcagcccg gtcgtcgtga cccggttgtg gagggcgatg
     1981 agcagcccct cccgtgaccc gtactcctgg cgcagcacct cgatgggcac acaggcagcc
     2041 tcgcacacgt cgtgctcggc cgtcgcccgg tatccgttga cgccgtacag ctccctggcc
     2101 gcttccagga gttgttcccg cgcctgtgtg cgcgcggcgt ccccgggccc ggtccgctga
     2161 accgtccagc tgtccgccac cggtcctcct tgagcgcaag gtgcgggaga ggagcctgcg
     2221 cgcctctgca cgaaccgccg ccccattgtg ctcgccccac cgccgtccgg acggccgcgc
     2281 cacacccgta cggggtaata cccgtacggg gaaacgcttc ttctcggcgc gtcgctcggc
     2341 gcgtcgggaa gtgggagcgc gccgagacct cagcgctgct cctccgcgta cgagaacgcc
     2401 tcacggtgct cgtccacgct ctcgacgccg tcgcgcgccc gcaaggacag gtcgcgggtg
     2461 agacggcggg ccagttcgcg caggacgtcg tccggcgtgg tcccctcgac gtactccagc
     2521 aggtcggtca gggcctccag ttcgcccgtg tgcagcgata cgtcggcgat ctcctggtcc
     2581 tccgccgtga gcgcctccac gatgcgccgc cggcaggccg tgtcccgcag gcgcgtcacg
     2641 acgtcgtcgg gacccgactc cgtgtcgaag gcttcgaggc gccggagcag tacgtccggg
     2701 tcgctgtgcg gcgcccggta gaagggccgc tcaccgctgc ccgcctcgcg cgggtccagc
     2761 cgcacctcgg agaggaacgc cgcgacccgt accggctccg gcgtcaggcc gctgcccatc
     2821 cagcgggccg agtccacgag cgagcggccc gacccctcag ggatgtggaa gaagcaccag
     2881 ccggagacac cgcaccagag cagccccgtc tcgccgccgt caccgaggag cctgcggctg
     2941 aacgcgcgcg tgaactccac gctcccctcg acatctcccg cgaagtcgtc ctggctcggg
     3001 tcgtgcacat ccccgtacgc cgaggtggag gccaccggga cctcctcggt cagcagcacc
     3061 tccgccacgc ccgccatgta accgcctatc accgattcga gcgcgccccg cagctgaggc
     3121 gagcggtctt cggcatcggt gtacgtcacg gcggttctcc cacgtcggtc gcggcggcag
     3181 gtccgcctcc ctatccgccg ttgcccgcat aatgcctgtt cacaccggtc gggctcgcct
     3241 ctgaggtacg gggcaggggc aggcgtcccc gcacccaccg tccagggctc agcccttgac
     3301 cgtgaactcc ctccgcagca gcgcctcgtc ccgggacgac gggcccacca gcagctcgaa
     3361 gcggcccggc tccaccctgc ggacgccttc cgcgtccacg agcgtgcagt cggccaccgg
     3421 gagttcgaag aggatctcgc gcgactcgcc cggggccagc gccacctgcc ggtaggcctt
     3481 cagctccttc tccgcccagg tcaccgacgt caccgtgtcg ctcacgtaca cctgcaccgt
     3541 ctccagcgcg ggccgcgcac ccgtgttggt caccgtgacc cgggcccgta cggtctccga
     3601 ctcgtcgacc accgccgtca gcacctccag gtccgtgtag gcgaccgtcg aatagctcag
     3661 cccctcgccg aacgcgaacg ccgggcgctg ggtgaggtcc gcgtagcgcg taccgtgctg
     3721 gccgcgcacc tggttgtagt acgtcggctg ctggcccgcg tgccgggcga aggacagcgg
     3781 cagccgcccg gtcggctcga tcaggccgag gagcagttcg gcgaccgccc ggccgccgag
     3841 catgcccggg ttggccgcgt acacgatcgc cgccgcgccg agcgcggagg gcggcagcac
     3901 cagcggcttg gagctgatga cgacgacgac cagcggcttc cccgtcgccg ccagcgcgtc
     3961 cagcaaagcg acctggtcgc cgacgagttc gagggtggcc gtcgacttgc cctcgccgat
     4021 cagctcgatc cggtcgccga cgacggccac cacatggtcg gccgcttcgg cggcggcgac
     4081 ggcctcggcg atcagctccg cgtcgggggc ggccgggtgg acgacctcgg ggcggggctg
     4141 cccgtcgggg aagaactccc cctccgggtc gggcccgacc tccaggatcc gggcgccggg
     4201 cgcgtacgag acggtccagt cggcgggcac gtggtcgcgg aagccgtcga ggaccgtacg
     4261 gatcatggcg cgcggctggc cgtccggcag ccagtccgcc tgcccggagg agcccgccca
     4321 gtcgcccaac tgggtctgcg cgtcatccgc gttgggcccg atgaccgcga ccgtacgggg
     4381 gccgggcccg gtggcccggc cctccccgtc ggccaccaga ccgcccgcga acggcagcgt
     4441 gccgtcgttg gccagcagca ccagcgagcg gcgggccgcc tccaggttca gcgccgcgtg
     4501 cgccccgctg ccgatgacct cggcctgccg gccggcgtcg gggtggcgcg ggttctcgaa
     4561 gaggccgagc tcgaacttga gcgtcaggat gcggcgtacg gcggcgtcga tctccacctc
     4621 cgtcaacgcg ccctgggcca cagcctcctg ggccccctcg aagaagttcg acgtggtcat
     4681 caccatgtcg ttgcccgcgc ggaccgcggc cgccgacgcc tgcgcgtagt cggcgtagac
     4741 cttctgctcc cacaccatgc ggccgacgtt gtcccagtcg gtgaccaggg tgccggtgta
     4801 gccccactcg ccgcgcaaca cctcgttgag cagccagttg ttgacggtga tcggcacgcc
     4861 gtccatcgac tggtagccga gcatgaaggt ccggcagccc tccttcgcga cccgctcgaa
     4921 cggcggcagg aaccaggagc gcagcttgcg gcgcgagatg tccgcctcgc tggcgtcccg
     4981 gccaccctgg gtctcggagt acccggcgaa gtgcttggcg caggccagga tcgcggtcgg
     5041 gtcgtccagg ccctcgccct ggtagccgcg caccatcgcg gaggccaact caccgatgag
     5101 gaaagggtcc tcgccgaacg tctcactgac ccggccccac cgcaggtccc gggtgatgca
     5161 gagcaccggc gagaacgtcc agtgcacccc ggtcgccgcg acctccaccg ccgtcgcccg
     5221 cgcgatccgc tccaccagct ccgggtccca ggtggcggcc atcccgagct gggtcgggta
     5281 gatcgtggcg ccctcccaga acgagtgccc gtggatgcag tcctccgcga cgagcagcgg
     5341 gatgcgcagc cgggtcttcg cggtgagcgc ggcggcctcg cgcacccgct ccggggacgc
     5401 gtgcaggatc gagcccgcgt gcaggtcctc gacgaggtgc cgcacgccct ccttggcgtt
     5461 gagctggagc atctggccca ccttctcggg cagcgtcatg cgccccagga ggtcggcgac
     5521 ccgctccgcg acgggcagcg cggggtcgag atacggcggc ttgggaccca caggacttcc
     5581 tttcacgacg cacgacggcc acaccggcca cgccggcgag agcggcactc gcagtaccgt
     5641 acgctcaatc ccgaccgctt ggtaagtatt cacccctgtg agaatctggg gcggaacgag
     5701 agaggcgtgg cgatgacagc gggtgcatac gcgtgacctc cggaacccgg cgcggctacg
     5761 ccaagggccg ggccaagcgg accgagatcc tcgaccaggc gatgaccctg ttcggcgagg
     5821 ccggctaccg gggcgcttcg ctgcgcgtca tcgccactcg ctgcggcatc tcccacccgg
     5881 ggctcctgca ccacttcccg acgaaggagg cgctgctcct cgccgtcctc cagcgccgcg
     5941 acgacgtgga cgacgagtgg ctggcgctcg gcgtcacccg gggcgtggac catctgcgcc
     6001 gcctggtgga cctcgccgag ctgaacgcca agcggcgcgg gatcgtcgag ctgttctcgg
     6061 tggtcgcggc ggaggccacg gcccccgacc acccggccca cgcgtacttc gaggcccgct
     6121 accgtacgtc cgtcgccaac accgaacggg cctacctcca ggcccgggag tcgggcgaac
     6181 tccgggacga cgtcgacccg tcggcggccg cgcagcagct catcgccctg atggacggcc
     6241 tccagatcca gtggctgatc agcgactgca cgacggacat ggcgggggtg ctgcgcgcgc
     6301 acgtccgcgc gcagctgacc gtggagttct gaaccggccc ggtggccacg ctcctcagcc
     6361 gaaggcgacg cccagcagat acggggtgag ggtcagcgtc agcgccaccg accagtacgg
     6421 gccggggggc gcggcaggca tcagcctgcg ccgcatccac aggttgagca gggtccacag
     6481 gcccccgaag cagcccacca ccgggacgac gaagaccagc cacggccaca tgccgtcgtt
     6541 ctcggtcggt tcccgctggg tccaccccag ctccgccagg ggcccgttgg acagcacgta
     6601 ccagatcagg aaggccggca cgatcgccgg aatcccgagc agcaggttcg ccgccaccgg
     6661 gacgcaggac ttccacagcc gcgcgccctt cacggagcct ccgtcaggat tcaaggactg
     6721 acccgctcga tcccgcggcg gccggcgatc cgggccacgg tgaggcagta cagcggggcg
     6781 aagacgagtt cggccaccat ggcctgccag ggggcgtcgg cggccgtctc ggtgctggcc
     6841 agttcgccga agccggccgc caggccgaag gcgagcaggt tgttggcgac gtgcatgacg
     6901 atcacggctt cgagcccgcc ggtccggatc acgagccagc cccaccacag cgccgagtac
     6961 agcagcagga ggaacccgga gagctcaccg aacccgtggg ccagggcgaa cagcagggag
     7021 gcgacgacta ccgcgggcca gggcgtgcgg acgacccggc cgatcacctg gaccagccag
     7081 ccccggaaga cgtactcctc ggcggcggcc tggaacggga cgagcgccag gatcacggcc
     7141 aggctcagca ggaagacggg ccaccccggg aagccggtcc ccgactcccc gaccggctcg
     7201 tcgttccacg tccacgcgat cagcacgccg atctgcacgg ccatcagcgg gaagcccacg
     7261 gcggcgcacc gcccgagcca gccccagcgc agccgcccga cgacggacga cacggtcccg
     7321 gcgggccgcc ggccgatcac gcgggcgccc cacaggacga tgggtatggc gatcgcgatg
     7381 ccgaggagct ggacgacgag gtcggcgacg gggtcctcga agaagaggtc gctgtccggg
     7441 tccgcgggag tcgcgtccag cagctccgcg aggaccatcc cgacgatgcc gacgaccacg
     7501 acggccagca ggaccagccc cacgacggcc gacagctcgc cgatccagcc gaaccgtccg
     7561 ccgtgaccgt tgcgcccctg ctcgtcgtag cgggaccccg agggcgcccg caccggcccg
     7621 gtcggcgggc ggctccactc cgggggccgg tcccagccct ggccgcccgg cccacccggc
     7681 caggccggtg cgggcgggtg cggcggaccg cccgccgacg acggcggggc ccagggcgac
     7741 ggcggaggca tggaggacga gggcggcgga ccgtccgtac gggacggccc gtccgaggac
     7801 gagggcggag gcggcggatc agaagggtgg ctcacatcag cgatcttcgg atgccgtgcg
     7861 tgcacgggtc aacgccagcc gtcctcgcga acccgggccg ccaggtcgat cttggtgtag
     7921 gtcggccggc ccgcctcctg gtacttggct ttcacccggt ccaggtagta cttcgccgtg
     7981 ttcaccgtga tcccggccct gcgggcggtg gccttcagcg tgagcccgga ggcgtacccc
     8041 accagcacct cgcgctcctg gggggacagc cgagggcgca tggaaccccg gtcgtaggcc
     8101 agagcgaagg ccagctccgg ggagtgggcg gtgcgcccgg ccgcgatctc gccgacggct
     8161 tcgacgagta cggacagctc ctggtccttc gtgagaaagc cgtcggcgcc gtcggtgacg
     8221 gccgcgacga tccggtcgcg gtccgccacc acgctgatca tcagcacccg gctgccggcc
     8281 gcccgcaggc ggcggatgtt gtcggcgggc ggccggtcgt cgcggagcat gaggtcgagc
     8341 agcacgacgt ccggcggctt cccggggccg gcgagcaact cgtcgacggt ggcggcgcag
     8401 gcgacgaggt ccacctcctc gactccctcg aaccacgacc ggatgccgtc ccgcagcatc
     8461 cggtcgtcgt ccaccacggc gacggtgatc accccggcca tctcagctcc acgcgcacgc
     8521 cctcgccggg ggcgctgtcc acgaaggccc gccctcccac gccgcgcatc cgggcatgca
     8581 cggaacggtc gagcccgatc ccgccggcgc ccggccgggc ggggccgggc ggcctcgccg
     8641 ctccgccggg cgcctccgca ccctccgatg cgcccgctcc gtccggtccg gcggctccgc
     8701 ccccgaaacc ccggccccgg tcgaccacgg tgacgatcag ccggccggag tcaccgccgg
     8761 cggtcaggaa ggcgtgcccc gtaccggcgt ggcaccgcac gttgttgagc gcctcggtcg
     8821 cggcccgcgc catggccagc gctatctcac cgggcacggc gggcggttcg tgatagcggg
     8881 cggtcacccg cagcccgagc gcttcggcgg cgcgtacgga ctcctccagt gcggcccgca
     8941 cctcggaggc ctgctcccgg tcgtccgcct gctcgaccag cctcctgaga tacgcggcct
     9001 cccgcgcgca acgctcgcgc atcatcgagg tgttggcgtc gacgccaccg cgggcaatgg
     9061 ccgtcagggt ggcgaggacg gtgtcgtgca acgcgttgtg atgggctacg cgctccgcga
     9121 acctggcccg ctgcgcctcc gcggccagcg cacgccggtt ggccgagtcg acctgcttgc
     9181 cctgccggca gagataccag gtgagcaccc aggagacgac ggcggagaag accagggcgt
     9241 tcagatgagc gccggtcacg gaggcgtccg cctccaccag gaggtacccg gcgagatgcg
     9301 tgaccaccag gagcacgacg gcgacggcga ggaggcgcgc ccggaaggcg acagcggcca
     9361 tggccgaaga cgatccgccc aggagcatga cccaggcgat cgattcctgg gcgtgggcac
     9421 cgccccaggc atacgcgccg aagggcagca ggcagccgat cgtcaggacg tcgaggccca
     9481 cggcccagga gacgagccgc cggtgccgcg ccgccatgaa ccagatgaga gcggtggccg
     9541 cgaccgcggc ccccagcgcg agccacggga acaggcggtc gtgctgatgc tgcgtcacca
     9601 cggcccctcc cgcgaccaga tgactgccgc ggtacagcgc ggtggcgatg accatcgtct
     9661 tccgggcccg gtgcagcccg gtttcggctc tgtcgatgcg acggcccccc ttgatcacaa
     9721 ccccccagaa cgggtggtgc accggcccct cggcgcaccg ctaacgtcac ccgtggcgat
     9781 caggggatcg ctcgcggcca cgataggcgg accccggccg aggccggtct gcgattcccg
     9841 gacaactcgg cagatctttc gatctgccgt ggccgaaaag gcatatgacg cagcatcacc
     9901 ctgtgtgtcg gcacccatgc cccgtacgcg gcgcccgccc ccccgccgac ccgcgccgcc
     9961 acgcaccgca ccgcaccgca ccggccagga aggatcgccc gtgagtacgc accgcgacga
    10021 acacgacagc ggcagcttct tcgcactgga caccggtctg ctgcccggca tcgtcgaagg
    10081 ggtgctgcac cggcgcgggg cgactcaatg gtcggtcgag cagggggagt tctggtgctc
    10141 ggtccggccg cacggtcatc ggagcggcga gcagggctgg aagctgcacc tctcggccac
    10201 tccgctgtcc gcggccctgg tcctggcggt ggcggccgac gtcctggtcg aggaacgggc
    10261 ctcgttcaag ttcgcggggg ccctggaccg ggtcgccctg ctgacgggcg ggcgcgccga
    10321 ccgcgggggc ggcggaaagt tcatcacggt ctaccccgac gagccggagc tgttccgccg
    10381 gctggcccgg cggctgcacg cggcgacgct ggggctgcgc ggaccacgca tcctgtcgga
    10441 ccggccgtac gcgccgggca gtctcgtcca ttaccgctac ggcgtgttca gcggggtgcg
    10501 gacgacgacg aacgacgggg acacggacgt acggctgcgc cgtcccgacg gcggactgga
    10561 gaaggaccgg cgtcaggcct gggtcaccac ccccgcgtgg gcaccgccac cgttcccgga
    10621 gccgacgccc tccccggagg cggtggcccg ctccggcgcc gtgccgagcc ggccgcggca
    10681 ggcggccgga ccgcggaagc cggagagtgg acccgcgagg aagtccgtcc gcctcaacgg
    10741 ccgttacgtg gtcgccaagg cgatccggca cgccttcaag ggcggggtgt acctcgcgac
    10801 cgacgagacc accggccgac aggccgtggt gaaggaggca cgggcgcatg tcggcgtccg
    10861 tatggacggc accggtctcc aggacaccct gcgccacgag gccgagatgc tggaggcgct
    10921 ggccccgctg ggcctcaccc cggccgcgat cgagttgttc gcccagggcg ggaacctgtt
    10981 cctggcccag gagttcgtgc cggggcggac gctgcgcgac cggctggtgg agcaaccggt
    11041 ccgggatctg gcggagttcc tggacctggg ccggcagatc gtggagatcg tggcggcggt
    11101 ccacggcacc gggcgggtac tgcgcgacct ctcaccgaac aacctcatgg tcacgcccga
    11161 aggccgggtc cggctcatcg acgtcgagta cctggccccc gagggcgttc cggtccgccg
    11221 cgggtacacc cccggctatg tcggccccga ggtgtcctcg ctgcgggact acgacttcac
    11281 gcctcccacg tacgccagtg atctctacgg gctcggcgcg gtgctgctgc acctggcgac
    11341 aggcgtcgac atgctcctgg tccccgacga ccgcccggtg ggcgaccgta ccgaggcgct
    11401 gatcaggtcg gcgatcgccg atcactcctg gacggcaccg ctcctgcccc tgctcctcgc
    11461 cctctgttcc ccgctccccg gggaacgttg ggaactgccc cgggtacgga aggccctggc
    11521 ggagctgccc ggctcagccc cacgcgccgc cgacggagac ggagacggag acagcgggag
    11581 cagcggagac agcggacgga ccggcggggc catgactccg gtcgcggact ccaccggtga
    11641 gggcggcctc ccggccctga gcgacgagga gcgcgagcgg ctgctcgccg atggcctcgc
    11701 ctacctgttg cgcacccgtc ctggcagcgg cggacacctc tgggacgtca gcgcgttcgg
    11761 cgcgaccacc gacccgctga acgtccagta cggctcggcc ggcgtcctcg ccgtgctcac
    11821 ccgggccgcg gcggcgggcg cgggagccga cgtccgcgac ggcgtggcgg agctgaccga
    11881 gtggacccgg cggggtctcg ccggcctccc caccggccgg accgccgacg gaacgcttct
    11941 gcccgggctg cacttcggcc gctcgggcac cgcctgggcg ctgctcgacg cggccatgct
    12001 gctgggtgac gactccgtcg ccgccgaggc gtccgcactg gcgcgcgcgg tccccgtcga
    12061 ctggcccaac cgggacatct gccacggggc ggccggagcc ggaatggccc aactgcactt
    12121 ctggcgcacg accggcgacc cggtcttccg cgaccgggcg gtggaatgcg ccgaggcgat
    12181 cgtggccgcg gcggaggatc accccgccgg ggtgatctgg cccgtcccgg ccaccttcga
    12241 ctcgaacctg gcaggagccc gtcactacgg gttcgcccac ggcatcgcgg gaatcggtgc
    12301 gttcctgctg gccgcgggcg tggcggcgga gcgcgcggac ctcgtccggg cggcccggac
    12361 ggcgggcgac accctggtga ggctggcccg gaccgggaac ggccgggcgg tctggccggc
    12421 cggggaccgg gacgccgacg ggccggtggg gcagacgcac tggtgcagcg gctcctcggg
    12481 catcgggacg ttcctggtcc ggctctgggc cgagaccggc gacgaacgcc accgggaggc
    12541 ggccgtactg gcggcggccg gagtgcggga ggccatgtgg ctctcctccc ccgccgcctg
    12601 tcacgggctc gccgggaacg ccgagttcct gctcgacctg tacgccgcgc tcggtgatgc
    12661 ccgcttccac gaccaggcgg ggcagttggc ggcgtgcatc cgcacccgtg ccgtacggcg
    12721 cgacgggctg ctggtggtgc cggacgaatc gctggaggcg gtcaccggcg gctaccagac
    12781 cggtgtcgcc ggcacggtcg gcatgctgct gcgcctgcgg gacgggggcc cgcggctctg
    12841 gatgccggac actccggacc tcttcgcacc cgtcggccgg aacccgcgta ccacggtggg
    12901 agcgcgatga accggcggcc ggaacgcatc agtttccgct tctcggcacg gtcccggttc
    12961 gccgcctgcc tggtgaccac gtccgacggc gcactggccc cggggtggtg ggacctcgac
    13021 ggcacacgtc cgccgtacgc cggtgacacg ccccgcttcc gggagggcgc cccgacggag
    13081 accaccgcca cccaggtgct cccgaccgaa tgcggcgggc tgctgcggct gcgcggcgcg
    13141 gcgggctccg gtcgtcacct gctcctgctg tcccaccccg catccgcagg accggtgacc
    13201 gaggagacca cgaccgccgg tactccgctc gccggacccc gggggccgtc ctcggccggg
    13261 accggccccg aggccccggc cccggccgag ggcgcggccg agtggctgtc cgtggaggcg
    13321 cggggcctgc gcctggtgcc cggcggcccg cgcggcacgc tcgcgctggc ggtggagacc
    13381 gctcacgacg gccgcacccg cgtctggcgg gtcaggtccg cgccgctgcg gctgagcgat
    13441 cccgtgaccc tgccgggccg ggtcaccgcc ctcctgccgc tcgacggaac gggctgccgc
    13501 tacgccacgg acctcgaagg gccggacggg taccgccccg tctccctgga cctgcgcgac
    13561 gggaaccggc tcgctctccc gtcgccgccg gacggccgca tccaccggct gctgctctcg
    13621 gcaccggcct cgggactgct gctgacggcg agcgaccccg gcgacgggcg gctgcggatc
    13681 gcccgcgcca cgctcggcct ccggcctcgg ctcgacttcc cggaccggct caactccctg
    13741 gacggagcgg tccttccgct ggccgccgac ccggcgggtg agcgggtcgc gctgcgggtc
    13801 tcccggggcg cgcaggcccg cctctatctg tacgacgtgg cggcggaccg gccccggccc
    13861 gccgagctgc cgccgggtgc gttccacccc gtggcgggct ggagcgaggg cgggctgcgc
    13921 gtcgtgtacg cggccccgga ccgccccgcg gacctggtcg gcgtcccgga caccgccgcg
    13981 cacggcgcac cggccacccc ctccggggcc gcgtccccca ccctcgacgt ctccgcgact
    14041 ccccacgccc ccaccgagtg gttcgccacc ccgtccggcc ggttcgaggc cgtccggctg
    14101 ggcgactggc gcaccgtgcc caccgtcgtc gtggcgctgc acggcggtcc ggaggaccac
    14161 tggacgctcg gccacgaccc ggtgctcgcg cgcctgtcgg agaccggggc ggcggtggtg
    14221 gcccccaacc agcgcggcag caccggctac ggccgggccc acgccgaggc gatccacggc
    14281 gcgtggggcg tacccgatct cgcggacatc cgggctctgg tccgtacgct cacggagcag
    14341 cgcccgccgg acgccgaacc acccgtgctg ctgggcacga gttacggggg cttcctcgcc
    14401 ctgctggccg tgtgcgccga cccgtacgcc tgggcacgct gcgcggtgat cgccccgttc
    14461 ctgtccgcgc gcggactgcg cgagcggtcg tcggccgccg tgcgtgcgct gatcgaccgg
    14521 cacggcctgg gcgagccgcc ggacgacggc ctcggcccca gggacgtcga acgcctcgcc
    14581 caccgcatcc gcgtaccgct gctcgccctg cacggctgtg acgaccctgt cgtgccggtg
    14641 gacgagacgc gccggctgcg ccgggcactg acgcgggcgg gcggcccgga acgcgtgccc
    14701 cacgactgtc tcgacatcgc gggagcggga caccacccgc tccaggagcg gggcggcgcc
    14761 gaactcaccg accggctggt gggcttcctg acggccgggt tcccggaccg ccgccgctcc
    14821 cccgctcccc ctggactcac ggtcgccgac gcggccgtgc ggcaccgccc atcctcggcg
    14881 gtgttcgggc acatcacgca cgacgaaagg acaccatcat gatcgacaac accatgaccg
    14941 tcgacgtcga cgagctgcag accctggagg gcgaggagtc cgtcgcgctg gccggctgca
    15001 cccggacctg tacctggacc tgctccatca ccagcatcga gcagcagtag cagccgtgcg
    15061 ccggacgggc ccctcgcgga cctgtccggc gcacgccgtg tctcccgtac gcacggctca
    15121 ccgcgatccg tgcccgtatc ccgtgcccgt ccgcccccgc gggagccacg gacggccgga
    15181 aggattccga tgacgtctcc ccggcgactg gtgtgggacg cgaccgcccg gacgcgtggc
    15241 tggttcgttc tcgcctccgc caccgccgcc ctgggtgcgg ccggcacact ggccttcccc
    15301 tgggcgatgg cgcgggccct ggacgcggtc gtcgcccggc ggcccgccac cggtcccgtc
    15361 ctcgtgtgcg ccgcgctcct cgccctcgtc gtcaccacgg gggccctcca gaccctcgcc
    15421 aacgggggct acggctccgg cacagtggcg gcgctgcgcc ggtccatggc ccggcgcgcc
    15481 ctcgacgcgg gggtgccggg gacggccggc ttccccgccg gggacctcgc ggggcgcctc
    15541 tccgccggat gcgcgcaggc cggatcggcg ggggtcacgc tggtcacggc ctcggctgcg
    15601 gtgctgacct cgctcgccgg ggtggtcgcg ctgtggctga tcgactggcg gatcgggctc
    15661 tgcttctcgc tgggcgtccc cccgttggtg ctcatcgccc gggtgttcat gaaccgcgga
    15721 tcggggctct tcctccggta ccaggagact cagggcagga tctccgccct gctgctggaa
    15781 gcgctcggcg gggcccggac catcggcgcg agcggcaccg cggcggccga gacgcgccgg
    15841 gtcctggaac ccctgccgga gctgtcccgc accggacacc gggtctgggc gctccagcgg
    15901 gacaccggat ggcaggtggg cctgctgatc ccggccgtcg aggtgctggt cctctgcgcc
    15961 gggggtctcg ccctcctcca cggtgacatc agcgcgggcg aactcgccgc ggtcgtcggg
    16021 tacacggcgc tcgcgatggc cgcgctggac cagctcgacg ccctcttcgc gctcggtatg
    16081 tcggccgccg gcgcgcgccg ggtcgccgag gtcgtcgacc agccggtccc ggcccccggc
    16141 acccgggccc gtccggcgag cggccccggc acggtaaccc tgtcgggggt gacggtgcgt
    16201 tccggtaccc ggctcgtcct ggactccgtg gacctggtcg tcccggcggg cacggcgctc
    16261 gcggtggtcg gacggtccgg ggcgggcaag agcaccctgg cggcgctgat cgggcggttg
    16321 cgggagccgg acgcgggcct ggtcgccatc gacggcgtac ccctgccgga gctgactccc
    16381 cgggccctgc gcgccgccgt cggctacgcc ttcgagcgtc ccgcgctgct ggggacgacg
    16441 gtggccggga cgatcgcctt cgcccgcccg gacgcctcac gggaggaggt ggcggcggct
    16501 gccggggccg cgcgggcgga cgacttcatc gcccgcctgc cgcacgatta cgacacccct
    16561 ctcaaggacg cacccctctc cggcggagag gtccaacgcc tgggaatcgc gcgtgcattg
    16621 gtccacgatc cggcggtggt cgtcctggac gacgcactgt cgagcctgga caccgcgacg
    16681 gaagcacggg tcggctccgc gctggcctcg gcctggtcgg cccgcacccg ggtgctgatc
    16741 gcccaccggg tgtcgaccgc ggcccgggcc gacctggtgg cctggctgga gaacggcagg
    16801 gtccgcgctc tgggcccgca ccaggagctg tggcgactcg acggctaccg ggccctcttc
    16861 gcggcgggca ccgggacgga aacggaaacc gcgccggaag ccgttccgga gcacgacccg
    16921 catccccacc cccaggagtc ggtatgagcg aggcagcccc gcgccccatc gaccggcatc
    16981 tgttcgccgg gttcctgcgg cagcaccggg gagcggcggt cgcggtggcg ggatggtcgc
    17041 tgctggaggc cgtccccgca ctcgcctccg gactcctcgt ggccgccgct ctggaccggg
    17101 gcttcctcgc gggccgaccg gccgagggct tcttctggat cggtctgctc ggggccgcga
    17161 tggtcttccg cgccctgatg acccggaccc tgacaccgtg gctggggcgg ctcgtggagc
    17221 cgctgcggga cgaactggtg acggccgtgg ccgcgggggc cgtacaccgc gcggcagcgg
    17281 gagtgcggga cgcggcgggc gcgggcgtgg cccggctgac ggtccaggta gagaccgtac
    17341 gggcgctggt gtccgccctg ctgcgctcgg cgcggcagct cggcgtctcc ctgctgatgg
    17401 cgttcgtggg cctggccgcc ctgtccgcgc cggtggcggc ggtcaccctg cccccggtcc
    17461 tgctcaccct gctcctctgc gccccccggc tccgcgtcct cgcccgccgc cagcgccgcc
    17521 aactgcgcgc cgaggaaggg ctcacggcgg cggcgggaga gaccttcgac ggcatccggg
    17581 acgtcgtcgc gtgcggcgcc caagaccggg tggccgacga cctgtccgcc cggatcacgg
    17641 accaccggga cgcggtccgg gcggtcgcga gggccgcgtc ggccaacacg ctgttggtgt
    17701 cgctgggcag ccatctcccc ctgctggtcc tgctcctggc ggccccgcgg ctcctggacc
    17761 ggggggcgct gtcggtgggc gaactgctgg gcgcgaccag ctatctgatc agcggggtcg
    17821 ctccggccct gcgctcactc gtcgccgtcc tcggctcgtg gggcgtgcag ctggcgaccg
    17881 tactgcgcca gttgagccgg tcgacgacgc aggggccgca cggggcggcg gaaagccagg
    17941 gccgggccac ctccccgcac accccacgct ccccgcacct gtccctggtg aacgtcggct
    18001 acgcctacgg tccgggcgcg gcacctgtca tcgacaggct ctccctcgac atccccgcgg
    18061 gctcccacct gacggtcgtc gggccgagcg gtgcggggaa gtcgaccctg acgaccctgc
    18121 tggccgggct tgccgcaccg gacaacggcc gactgaccct gggcggcgtg ccggtgacgg
    18181 aggtcgaccg ggcctggctc caccgggcgg tgacgctgat cccgcaggag gcgtacgtgt
    18241 tcaccggcac cgtgcgggac aacctccgct acctgcgccc cctggccaag gacgccgacc
    18301 tcctcgcctc cgcgacggcc gtgggcgcgc gagccctcgt ggaccggctc ggcggcctgg
    18361 acgcgcccgt cgggcttgac ggccccccgc tctcctccgg ggaacggcag ctcgtggcgc
    18421 tggcccgcgc ccatgcctcc cccgcgtcgg tcgtgctgct ggacgaggca tgctgccacc
    18481 tggaccccgc ggcggaggag cgggccgagc gggcgttcgc ggcacggggc accacgctcg
    18541 tcgtggtggc ccaccgcatc agctccgcgc tgcgcgcgcc gcgggtcctg gtgctcgacg
    18601 gcgagcgcac cgccatcggc acacatgccc aactcctgga cgagagcccg ctctacgcgg
    18661 acctggtggg ccactgggtg gccgccggaa ctccgtaggc gttgtggcag actgcgtcga
    18721 ctgactggtc cacaccacgt gtatctggag ttcggtatga cggcacagac gcctcacccc
    18781 ccgatcgaca ccagcaagcc gcactcggcc cgggtctacg acgccctgct gggcggcaag
    18841 gacaactacc cggtggatca gcaggtggcc gaactcctgc ccgtcgaggc gaagatcggc
    18901 gcccaccagc agcgggcctt catgcaccgc gcgacggcgt ggctggcggg ccagggcgtg
    18961 acgcagttcc tcgacatcgg cacgggcatc cccaccgaac cgaacctgca ccagatagcc
    19021 caggagatcc gcccctccgc ccggatcgtg tactgcgaca acgaccccat cgtcctgcgc
    19081 cacgccgaag cgctgctggt cagccgcccg gacggtgtga cggactacgt ccacgcggat
    19141 gtccgcgagc ccgcgatcat cctcgacgcg gcccgcgaga ccctggactt cgaccgcccg
    19201 atcgccctgt ccctgctcgg cctcctccac ttcctccccg acgccgagaa gcccatcgac
    19261 atcatccgta cgttcaccga cgccatggcg cccggcagtt acgtcgtgct gtcccacggc
    19321 gcgtccgacg tgaacgagga gaagggggag cagagcgcgg acgagtacaa gaagggcggc
    19381 atccaactgg ccctgcggac acgggaggag ttctcccggt tcttcgaggg cctggagatc
    19441 gtcacccccg gcctggtgaa ggcccctgag tggttcaacg gaacgcccgc gcccgagcag
    19501 gagcacagcg gcatgtacgt cgccgtggcc cgggtcccgt agccggaagc ctcgcgcact
    19561 ccgagggtga gccggcgtaa gtgccggctg caccttcgga accaggccgt ccttggatca
    19621 cttccgcctc ggatcacttc cgccggccga ggttgtcgtc gatgatgtgc gtgtgaccca
    19681 tcgcatcagc gctctgatct ccgtcttcgg cgtcttcgcc agtgtgttgc ttctcgctct
    19741 cgccgttcgt gagtaccgct ccggggccac ggttctgtgg ctcgtgttcg gagccacggc
    19801 cttcctcggt gctgtgtacg cgctcgtggt ggacgtacgg cggctccgca cggggccgac
    19861 cgcctgagaa ccggcgagga gaggtgcccc cttggtgctc ctggcactgc cgtgtcggac
    19921 gcggaaggag agctgaggcc tcgctcattc cttcacggcg caccccgccc gcagccaggc
    19981 catttcgtgc agcagcgcac cgtccacgaa ggggtcctgg gccgtgggcc gcgacctccg
    20041 gtccagcggc caggtcccgc cgcccagcgc gggcaccccg acgaacgcgt ccccccgcgc
    20101 gctccggctc atcgcctcca ccccgggagg ccaccggtgc tcggcggcgg tcccgggtgc
    20161 gagcaggaag tacatgctgc gctcgccgat gccggagcgg acgatggggc cggcctggaa
    20221 gtcggtgaac tgcatgacct cgtaagcgat ttcctctccg agcaggccga tggcccgtac
    20281 ggcgtcgaag tggatgccga cgtggcggag ggcgtggccg gaggcgggga tccaggcggg
    20341 gcagaagggg gccggatccg gtgaattctt cagttccatg cgctcagcgt tgcggcagac
    20401 acgtacggtg accagggtca caagcacgtt gtgaacagtg gtgtacatgt gaggtgagcc
    20461 cgtgcactcc agtgatcagc cggaaagcac cgccgagatg ttcggtctgc tgctgcggca
    20521 cttccgcgtg ctggccgggc tgtcacagga ccagctgggc aaacggatcg gctactccaa
    20581 gtcccaggtc gccatggtgg aacggggcgc ccgtccgccg acggacgtct tcgtccagcg
    20641 ggcggacgag gtgctgcgcg cacagggtgc gttgatcgtc gccgcaccga agccgccgaa
    20701 gcagacggag cggcggaacc cgctgccggg gtggttcacg ccgttcgcgg acgaggagga
    20761 gaaggcgtgg gcgaggcacg agtatgagaa ccacgtcatg ccgggtctgc tccagacgga
    20821 ggcgtacgca cgggccgtct tcacgagccg gtacccgacc tatgacgacg acgagatcga
    20881 agcgaaggtc gccgctcgcc tcgaacggca gaagctcctg tcccgcaggc cgctgccgga
    20941 catcagcttc gtcctggaga tgtcggtgct gacccggccg atcggcggcc gtcgcgtgat
    21001 gaaggcccag ctccatcacc tcgccgaggt ggcgcggctc cggcacgtgc gcatccagct
    21061 gatggatccg gaccgggagg accacgcggc gctggacggc ccgttcgtcc tgctggagac
    21121 cgacaagcgc cagcagctcg cctacatcga ggggcagggc ggcagcttct tcgtcaccga
    21181 acaacctgag ctggggaacc tgttcggcaa gtatggcgtc accagggccc aggcatacac
    21241 tccggagagg acgctggaga agatcgagaa gatggcagag gaactatgag taccgacctc
    21301 cactggttca agtccagcta cagcggcagc gagggcggca actgcgtaga ggtggcgctc
    21361 acctggtcca agtccacgta cagcggcccc cagggcggca actgcgtcga ggtggccacc
    21421 tgcccccaca ccgtccacat ccgcgactcc aaggacctca ccctcaccgc cctcgccgtc
    21481 tcccccgaca cgtggacgtc cttcgtggag ttcgccgcgt cctaagcggc ctccacccac
    21541 tccggcgccc acacgtcctg cggggtgcgc gggcccgccg tgcgcagata gtcgcgcagc
    21601 gcggtcagca cggggtgctg gtctccgctg cggaagagca gcacatgcgg gtagaccggc
    21661 gtcgggtcgc gcaacgggat gcgccggagg tcgtgggcct ggggccacag atagcggtcc
    21721 ccgcgcccga ccagggtggc cagggagtcc gactccgcca gcgtgtccat cagggcctcg
    21781 gggccgaagt cggggccgag ggcgtcgatg ctcaggccga aggcttcgga cagcgtccgg
    21841 tagaacgccg cccactccgt gccgggcatg atcccgggga tccagatgcg gtgaccggcc
    21901 agttccgcag gactgacgtg aggcgcgtcc gccagcgggt gtccggagcc gaccaggagc
    21961 tccagaggtg cgtccatcag ccgttcggcg ctgatcccgg ccgggacctg gtcggccggc
    22021 agggcgcgga aggacgcgtc gaccgtccct tcgagcaccg cccgggcggc ctgggcggcg
    22081 ttctccgtgc tcagcgtgac cacgtccagc tccatctccg ggtgggagcg gtagaaccgg
    22141 tggacggcct gcgccgggga gatgcgccgg ttgaggacgt cgacgcgcag gggacggttg
    22201 ccggggcgta cggcctgctc ggcctgctcg acgaccgcca ggatcttctt cgcgtgcggc
    22261 aggaagacct gcccgtccgg gctcggccgg gagcctcggg aggtccgcac caggagcatg
    22321 accccgaggt gccgctccag ggccgcgatc cgcttggaga ccgcctgctg gctgatgccc
    22381 agctcgtcgg ccgcggcctg gaactggccg gtctcggcga cggcgacgaa cgtccgcagc
    22441 gcttcagcat ccacacgccc accctacttc cacaactaga agttgtcttc ggtgcagcgc
    22501 ggagttgttt gatcgagcac tccgcgcggt ggtgggatca gcgcatgtcc actcgcacag
    22561 agcacgtcat gtatgtcaag acacccgatt tcacgcgtca cgcggaacgg atcgtggagg
    22621 tgaccgatgc gacgtcccga ctgaacgtgc ttccgttcag cgacacagaa ggtcgcgctg
    22681 aactactttc ggttgtgttc ggcggcccgc taccgccgtc ggtgacgatc tacccgccgt
    22741 tcttcaccga gtacgggctg aacacgacat tcggggagaa cgtcttcgtc aaccagggat
    22801 gcaccttcat ggacaaagga gggattcgca tcgggaacgg cgtcatgatc gccccgaagg
    22861 tcagcctcat caccggaggc cacccgctgc ccctggccga gcgccgtgag
//
