LOCUS       NZ_CP029361            11368 bp    DNA     linear   CON 31-MAY-2024
DEFINITION  Streptomyces globisporus strain TFH56 chromosome, complete genome.
ACCESSION   NZ_CP029361
VERSION     NZ_CP029361.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces globisporus
  ORGANISM  Streptomyces globisporus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7488586)
  AUTHORS   Cho,G.
  TITLE     Complete genome sequence of Streptomyces globisporus TFH56 isolated
            from tomato flower
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7488586)
  AUTHORS   Cho,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAY-2018) Division of Applied Life Science, Gyeongsang
            National University, Jinjudaero, Jinju 52828, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 29-MAR-2018
            Assembly Method :: canu v. 1.7; arrow polish v. SMRT link 5.1.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 37.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003147545.1-RS_2024_05_31
            Annotation Date                   :: 05/31/2024 02:17:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,917
            CDSs (total)                      :: 6,829
            Genes (coding)                    :: 6,492
            CDSs (with protein)               :: 6,492
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 337
            CDSs (without protein)            :: 337
            Pseudo Genes (ambiguous residues) :: 0 of 337
            Pseudo Genes (frameshifted)       :: 240 of 337
            Pseudo Genes (incomplete)         :: 121 of 337
            Pseudo Genes (internal stop)      :: 7 of 337
            Pseudo Genes (multiple problems)  :: 31 of 337
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:15:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 298969
            Orig. end                         :: 310337
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029361.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..11368
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="4"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11368
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11368
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6368](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..6368)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(395..409)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.21"
                     /tool="antismash"
     misc_feature    complement(1065..1081)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            complement(1697..3436)
                     /locus_tag="DIJ69_RS01395"
                     /old_locus_tag="DIJ69_01395"
     CDS             complement(1697..3436)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955801.1"
                     /locus_tag="DIJ69_RS01395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_01395"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_030804858.1"
                     /transl_table=11
                     /translation="MMLHPELLRAAHTARRPLGLATALLAAVTATHLAQAVLLALVLSR
                     IAQGETASLAPLLTAVIAVVLVRAALGRAQRLVAVTAGATVRVRLRDTLLERLGALGPT
                     AITGARAGAVRATLVDGVEGVDAYISRYLPQLLITAAVPPLLLVAVALVEPYAALALGP
                     ALLLALFGPRWWDRLLARRGKEHWDTYEALAADYLEALQGMPTLRSAGAVGRVRERLER
                     RSAALHRSTVAKLRVSLVDTGLTDLAVQGGTVAAVLVACSSAATGRTAATGTYLLLLLA
                     SECFRPVRDLSREWHAGYLGVSAADGIAALRTAEAAVPDRGTVTAVWEGPPEIRFDDVH
                     FTHPGSARPALDGVSFTAAAGRTTAVVGPSGAGKSTVLSLLLRQRDPDGGRVTVAGTDT
                     AAYALASLRRGIAVVSQETYLFHATIAENLRVARPAATDGDLRTAARTAGIDEEIVRLP
                     DGYATLVGERGATLSGGQRQRLALARALLADAPVLILDEATSAVDERGQARIVRELAAA
                     GRGRTCIVVAHRLDAVRHADHIVVLDAGRVAAAGDHTTLLAGGGVYASLVAAGRTTQEE
                     RAA"
     gene            complement(3433..4986)
                     /locus_tag="DIJ69_RS01400"
                     /old_locus_tag="DIJ69_01400"
     CDS             complement(3433..4986)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964398.1"
                     /locus_tag="DIJ69_RS01400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_01400"
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_044377303.1"
                     /transl_table=11
                     /translation="MPDTTYRAAAPVCGVGAALPAAPDVLRAALADARSPRVPELSPYV
                     PERPFPWNGPRTTYASEPGTAIDLDRALRLSLAAPAGTPGRLRPVPSAGALHPVRAHLL
                     LGRKCSLPPGLYAYDPRTHRAHRRGPAPDGVPSGALIVLTVAASRTVAHYGHRAWPLLL
                     LDTGHAAAALALAGATNADVLVSLDADGRLLSAAAGLPEAPDWQAIWPGTEPELPLAAV
                     RLMPPGCPVEAGTPLRAWAALPRASAPTPQPGAGTAPPRELAAARHLLHHIAGASGRPE
                     GTWHPAHRPGELTDEALGARRSAPPEDLTRPLNKELLTRILATVQSARPDGPAWTVALG
                     GVTPALYAAAPGRPGLDLRAVGDARPTLAHWAAGQQWIGAAGAVLLAHGCPEDAPRATV
                     RSSHLTAGYAVGVAQAHATARGLPSRPVGSWQQADLGAALGDTPGRDWIVHGLALGAPP
                     TTAATPVTKAAALARPAVTPATTAAGPATPAATPAPTPAATPPTASAAPAAPPGEEERP
                     "
     gene            complement(5001..6368)
                     /locus_tag="DIJ69_RS01405"
                     /old_locus_tag="DIJ69_01405"
     CDS             complement(5001..6368)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059075.1"
                     /locus_tag="DIJ69_RS01405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_01405"
                     /product="YcaO-like family protein"
                     /protein_id="WP_078955725.1"
                     /sec_met_domain="YcaO (E-value: 6.2e-42, bitscore: 143.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSALPLEALVDSVSGIVRAVAPVEHPAGAPPRYTAMTADVADAR
                     RLGAWPADRVSLGTTFGDPRGAWIAAVAEAVERYCGNRLPPPGQPQEPRRATAAELTAE
                     GSRLYGPGALPAYAPWQYGRPGFPYAELVPDTPALWTRAVENGELCWAPVALTHLNWRQ
                     GELRSLPRTHHLNYAGIATGQGLDDAVERGLLEVVERDALELWWHLDGPTRGIDPASVP
                     GLTEDLAGCALDVHIVEMPSEFAPCVAALVHDPGRGMYAAGFACRYDPAEAARKAVLEA
                     VHTWVFTQGAVDADGWVYRAVEAGMLARGLYLDHRADRRYLDDCGPEFAAVRDLGAHVQ
                     VWLDDRMAPLARRFTEPALGVVPVTAITPGSRTALDGALAAGGHRVITADLTTEDVAET
                     TLRVARVLVSGLIPNAPAAFGYFGCPRFAEAALARGWRTRPPAAPEDFTLAPPPHM"
     gene            complement(6365..7936)
                     /locus_tag="DIJ69_RS01410"
                     /old_locus_tag="DIJ69_01410"
     CDS             complement(6365..7936)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377868.1"
                     /locus_tag="DIJ69_RS01410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_01410"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_044377294.1"
                     /transl_table=11
                     /translation="MNTRTVSVPAPDGTPLATDVCLPDGNRPRPAVLIRTPYGREAHRA
                     ELRGWAAHGFAALAQDVRGRHGSPGEWHPYQDQEKADGAATVAWVRAQAWSNGEVVAVG
                     ASYAAYCALVTALDDPDAAPGVVQGDGIPDAVIAAVPALGLSETAREPGGPERLWARAG
                     WWAAHGDRRDSDPDALERALADDPRLLEHLPVARLAERMATGLERELPSWPRLWADRER
                     GRLIALGSSVGLPLLAVGGTRDPFAEDTVALWRGWGGPARLLLGPWGHRLTADRTAPAR
                     ARVNLGALYVRWARAALAARLEPTRHGVIALGDSGRWHTTRVRGTQRPGTAPEAECRWP
                     FGSSTGLRLLHGAEFSADPQRPVRSDDLAVPVDGDHADRCLLLSPPLPRPLDLAGAAVA
                     RIAVTADTPSADWAVRLTALDPSGRADPLAFGIVRRTGPPGEAADITVPLGTLGRRLPA
                     GTRLRAEIAGHHFPAHARNPHTGDDPVTAIRLVPSRRTVNPRGSALHLPVVARRRYVEP
                     VPEICR"
     gene            complement(7933..8961)
                     /locus_tag="DIJ69_RS01420"
                     /old_locus_tag="DIJ69_01420"
     CDS             complement(7933..8961)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072943.1"
                     /locus_tag="DIJ69_RS01420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_01420"
                     /product="hypothetical protein"
                     /protein_id="WP_181138372.1"
                     /transl_table=11
                     /translation="MTRSRLAPGTGIVTVPGAAPVLRTSGGEFLRIDTRGVTGEALVRR
                     LAGEEAPGGQPSAEEPLTAELVRLVEAFEAGGHAVSVPPRAPLAGRTVHVLGDPVLTGP
                     VARCAGAEGAEVRRITPDQVAELARAVPDRGRPEGCVAVVWCLDSPVPEGLWDTADRLP
                     DRRIAWLRSHREGSHSWIEPLAAAPGDVTSRHVRLRRLAATPAHRELAAYWAGHRTPDT
                     GPHPTEASAALIAALLTADLIAWAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAEAE
                     AAGGVGRQPAGLPPRRRLRRIDLRDLTFTEHPVLPVPDVAPLPVPAPVGTRAGESAAEA
                     RA"
     gene            complement(9102..9236)
                     /gene="amiA"
                     /locus_tag="DIJ69_RS35195"
     CDS             complement(9102..9236)
                     /codon_start=1
                     /gene="amiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508296.1"
                     /locus_tag="DIJ69_RS35195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="streptamidine family RiPP"
                     /protein_id="WP_006129278.1"
                     /transl_table=11
                     /translation="MEQNKVFSPIADQGQLAHLSATHSNALVENPFDDAVEADTAAEK"
     misc_feature    9215..9229
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.28"
                     /tool="antismash"
     misc_feature    9304..9317
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.45"
                     /tool="antismash"
     misc_feature    complement(9304..9319)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.88"
                     /tool="antismash"
     gene            complement(9305..10150)
                     /locus_tag="DIJ69_RS01425"
                     /old_locus_tag="DIJ69_01425"
     CDS             complement(9305..10150)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059071.1"
                     /locus_tag="DIJ69_RS01425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_01425"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_044375009.1"
                     /transl_table=11
                     /translation="MASATPRTPDVVRAEGLAFGYPGRPVLRGVDLSIRAGELVALIGL
                     NGCGKSTFLKLAAGLLTPSGGRVLLDGDDVARLPRRTAARRVALLHQSAPSVPGLTVRQ
                     LVRQGRYAARGPLGMLREGDDEVTSRALADVGVTGWADRPVDALSGGERQRVRLAMALA
                     QDAPVLFLDEPTTYLDLRHQLEVLQTVVRLRAERRLTVVLVLHDLNHAARFADRIVALR
                     EGRIAADGPPAEVVTRHLLAEVLGVDGRVGIDDEGGWPVCYPDHPLDPLQLLRNENHIH
                     "
     gene            complement(10189..11247)
                     /locus_tag="DIJ69_RS01430"
                     /old_locus_tag="DIJ69_01430"
     CDS             complement(10189..11247)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955794.1"
                     /locus_tag="DIJ69_RS01430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DIJ69_01430"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_030804839.1"
                     /transl_table=11
                     /translation="MTFVDAAPVPARRALRAPGVRIGGLTLLVAVVACAGLFAGRGVTP
                     EGVRAVLLGAGGDPTAEHIVLQLRLPRMLVALVAGACLGVAGLVLQSALRNPLAGPEVT
                     GVTPGAVLGAVTATGLGLAGWESPTAVVVAACVGGFAGAGLLWLLAGRDRGDPEQTAVY
                     GVLVSAVLAGLTAVVLLVAPGELGSVVQWLIGSTEGRVWQHWNLLWPWAAIWGAAAWLL
                     AGPLTLLRCGDEQAAAAGLATGRGRGAALVCAVALTAGAVSAVGALGFVGLLVPHLALA
                     VFGADLRVTLPGAALLGAAVVCGADAAAQLLSRLLATALDADRLTLPVGALTTCVGAGL
                     LMVVARRRADER"
     misc_feature    complement(11233..11247)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
ORIGIN
        1 gcccgggtgg cggagccggc cgcgagcgcc cgggccagtt ccgcgtcacc ccggtggtcc
       61 agatgggcgg tcgtctcgtc caggacgagg acgcgcgggg cgctcagcag cgcccgggcc
      121 agggccaccc gggcgcgctg gccgccggag aaggtggcgc cgcgctcgcc gaccggggtg
      181 tcaagaccgt cgggcagggc gtcggcgacg gtgtcgacgc cgcagatccg ggccaccgcc
      241 tcgagttcgt ccgccgtcgc gccgggggcg cccaggcgga ggttctcggc gagcgttccg
      301 tggaagagcg gggtctcctg ccccaccacg gacacggcgg cgcgcagctc gtcctcggcg
      361 agctcccgca ggtcaacggg gtgagccggg gcggggggaa cgagttccag ggtgccttcg
      421 gccgggtccc agtaacgggc caggaggtgg gcgcaggtcg acttgccggc cccggacgct
      481 ccgacgaggg ccacggtctc acccggccgg acggtgaggt cgacgccgtc cagcacggcc
      541 tctcccccgt agccgaaccg tacgccgcgc agccgcaggc cgagcgggcc gggcggtacg
      601 gggcgggggt cggcgggggc gggggctccc gcgggggcgt gcacggcggc ccggacccgg
      661 gccgcggcgg cgcgcagacc acccgcccgg ccgagcgcgg ccgccgattc cgcgaccggg
      721 gcaagggcgc ccagggcgag cgccatggcg gccggggccc aagccccgtc gagccgtccg
      781 gcggacgcgg cgtgggcggc ggccgccacg accccgatga cggcggcgac gaccagcagg
      841 tcgcgggccg cgcccgcacc ggtctcccag gactgttcgg cgcgctgggc gcgggcgagc
      901 cgccgcccgg cggaccggag ccgggcccgc ctgcggttca gcgaccccgt catcaggagc
      961 tcgcgcagtc cgtcgacgct ctccacggtc tccgacgaca gctcggcgag cgcgctccgg
     1021 gtgcggtgcc cgcgctcggc ccgcccgcgc gcttcgagga gcggtgacca gatcagcagc
     1081 agcgcggccg ggacgacggc gagcagcagc cagggcccga gagcggccag cacggccgcc
     1141 gacaccgcga agaccacacc ggacgcgagg agttgcgcga tggcgtgggc gtagaagaac
     1201 tccagtgcct cgacgtcccc gagcgcggtg gccgcgaggt cgccgctgcg ccggcccgcg
     1261 atccgggcgg gggcgctgcg ggccagtccg tcgaagaccc ggacgcgcag ttcggccagg
     1321 acccggtagg ccaggtcgtg cgagaggtcc atctcgcgcc aggtggcgag tgcccggagg
     1381 aggacgaggc cgatcaggac ggcgacagtc tcgggggcgg gcgggcggtg ctcggtgacg
     1441 gctgtgccca ccgtgtacgc ggcgagggtg accagggcca ccaaggcggc ctggtcgacg
     1501 agggcggcca gacaggtgcg aagcacggtg gcgcggtgcg cgccgaggac ggggaggagc
     1561 gagcgcaggg cgccggccgg ggccgggtcc ggagcctggg tcgtgcgcgg gggcggggca
     1621 gggggctgag cctgggccgt gcgcgggggc ggcggtgagt cctgggacgg ggactcggtc
     1681 gcgcgggggt tcggagtcat gcggcgcgct cttcctgtgt ggtgcgtccg gccgcgacga
     1741 gcgaggcgta cacgccgccg cccgcgagca gggtggtgtg gtcacctgcg gcggccaccc
     1801 ggcccgcgtc gaggacgacg atgtggtcgg cgtggcgcac ggcgtcgagc cggtgggcga
     1861 cgacgatgca ggtgcggccg cgtccggccg ccgccagctc ccggacgatg cgcgcctggc
     1921 cgcgttcgtc gacggcgctg gtggcctcgt ccaggatcag gaccggggcg tcggccagca
     1981 aggcccgggc cagggcgagc cgttggcgct ggccgccgga gagcgtcgcg ccgcgttcgc
     2041 cgacgagggt ggcgtaaccg tccgggagcc ggacgatctc ctcgtcgatc ccggcggtcc
     2101 gggcggcggt acgcaggtct ccgtccgtgg cggcggggcg ggcgacgcgc aggttctccg
     2161 cgatcgtggc gtggaagagg tacgtctcct gcgagaccac ggcgatgccc cggcgcagcg
     2221 aggcgagggc gtacgcggcg gtgtccgtcc cggctacggt gacgcggccc ccgtccgggt
     2281 cccgttgccg cagcaggagg ctcagcaccg tcgacttccc agcgccggac gggccgacga
     2341 cggcggtggt gcgcccggcg gcagcggtga aggacacgcc gtcgagggcg ggccgggcgc
     2401 tccccgggtg ggtgaagtgc acgtcgtcga aacggatctc gggcggcccc tcccagacgg
     2461 cggtcacggt gccccggtcc ggaacggcgg cctcggcggt gcgcagggcg gcgattccgt
     2521 cggccgccga caccccgagg tagccggcgt gccactcacg ggagaggtcc cggacggggc
     2581 ggaagcattc ggaggcgagc agcagcagaa ggtaggtgcc ggtggcggcg gtgcggccgg
     2641 tggcggcgga tgagcacgcc acgagtacgg cggcgaccgt gccgccctgg acggccagat
     2701 cggtgaggcc ggtgtcgacg agcgagaccc gcagtttggc gacggtgctc cggtgcaggg
     2761 cggccgaccg tcgctccagc cgttcccgta cgcggcccac ggcaccggcg ctgcgcagcg
     2821 tcggcatccc ctggagtgcc tccaggtagt cggcggcgag ggcttcgtag gtgtcccagt
     2881 gctccttgcc gcgccgcgcc agcagccggt cccaccagcg cggcccgaag agggcgagca
     2941 gcagggcggg cccgagggcg agggccgcgt acggctcgac gagagcgacg gcgacgagca
     3001 gcagcggcgg gacggcggcg gtgatgagga gttggggcag gtagcgcgag atgtacgcgt
     3061 cgacgccctc gaccccgtcc accagcgtgg cccgtacggc tccggcccgc gcaccggtga
     3121 tcgcggtggg gccgagcgcg ccgagccgct ccagcagggt gtcgcgcagc ctcacccgta
     3181 cggtggcccc ggccgtgacg gcgaccaggc gctgggcgcg accgagggcg gcacggacca
     3241 ggacgacggc gatcacggcg gtgagcagcg gggcgaggga ggccgtctcc ccctgggcga
     3301 tccgggagag cacgagggcg aggaggacgg cctgggcgag gtgggtggcg gtgaccgccg
     3361 cgagcagggc ggtggcgagg ccgagcgggc gccgcgcggt gtgcgctgcg cgcaggagtt
     3421 cggggtggag catcatgggc gttcttcctc gccgggcggg gcagccgggg cggcggatgc
     3481 cgtgggtggg gtggcagcgg gcgtgggggc cggggtggcg gcgggcgtgg ctgggccggc
     3541 ggctgtcgtg gccggggtga cagcgggcct ggccagggcg gcggctttcg tgaccggggt
     3601 ggccgctgtc gtcgggggtg cgccgagggc aaggccgtgc acgatccagt cgcgtccggg
     3661 ggtgtcgccg agcgccgcgc ccaggtcggc ctgttgccag gagccgacgg ggcgcgaggg
     3721 caggccccgt gcggtggcgt gcgcctgggc gacgccgacc gcgtatccgg cggtgaggtg
     3781 actgctgcgg acggtggccc gcggggcgtc ctcggggcag ccgtgggcga ggagcaccgc
     3841 gcctgcggcg ccgatccact gctggcccgc ggcccagtgg gcgagggtgg gacgcgcgtc
     3901 gcccacggcg cggaggtcga ggcccggcct tccgggagcc gctgcgtaca gggccggggt
     3961 gacaccgccc agggccacgg tccacgcggg cccgtccggc cgcgcgctct gcacggtggc
     4021 caggattcgc gtgagcagtt ccttgttgag cgggcgggtc aggtcctcgg gcggggcgct
     4081 ccggcgcgcc cccagagcct cgtcggtcag ctctccgggg cggtgggccg ggtgccaggt
     4141 tccctcgggc cgcccggacg ctccggcgat gtggtgcagc aggtgccgtg ccgctgcgag
     4201 ttcacggggt ggggcggtgc cggctcctgg ttgtggcgtc ggggccgagg cgcggggcag
     4261 agcggcccag gcgcgcagcg gcgttccggc ctcgacgggg cagcccggag gcatcaaccg
     4321 tacggctgcg agcggtagtt ccggttcggt gccgggccag atggcctgcc agtccggagc
     4381 ctcgggcagt ccggcggcgg cggacaggag gcggccgtcc gcgtcgaggg agaccagcac
     4441 gtcggcgttc gtggcgccgg cgagcgcgag ggcggcggcg gcatgacccg tgtcgaggag
     4501 cagcagcggc caggcccggt ggccgtaatg ggcgacggta cgggacgcgg ccacggtgag
     4561 gacgatgaga gctcccgagg gtacgccgtc gggggccggg cctcgccggt gggcgcggtg
     4621 ggtgcggggg tcgtaggcat atagcccggg cggcagcgag cacttccgcc cgagcagcag
     4681 atgggcacgc accgggtgca gagcacccgc cgagggaacg ggtcgcagcc ggcccggcgt
     4741 gccggcgggc gctgccaggg agagccgcag cgcacggtcc aggtcgatcg cggtcccggg
     4801 ctcactggcg tacgtggtcc tggggccgtt ccacgggaac gggcgctccg gaacgtacgg
     4861 ggagagctcc ggaacacgcg gcgaccgagc gtccgcgagc gccgcgcgca ggacgtccgg
     4921 tgcggcgggt agggcggcgc ccaccccgca aacgggcgcg gcggctcggt acgtcgtgtc
     4981 gggcatggtg gcgtgctcca tcacatgtgc ggtggcgggg cgagggtgaa gtcctcgggt
     5041 gccgcgggcg gtcgggtgcg ccagccccgg gcgagcgccg cttccgcgaa acgcgggcag
     5101 ccgaagtagc cgaaggcggc gggggcgttg gggatcagcc ctgagaccag gacccgggcg
     5161 acgcgcagcg tggtctccgc gacgtcctcc gtggtgaggt ccgcggtgat gacccggtgg
     5221 cccccggcgg cgagtgcccc gtcgagcgcg gtgcggctgc cgggagtgat cgcggtgacc
     5281 gggacgaccc ccagggcggg ttcggtgaag cggcgggcga gcggggccat ccggtcgtcc
     5341 agccagacct ggacatgggc gccgaggtcc cggaccgcgg cgaactccgg cccgcagtcg
     5401 tcgagatagc gccggtcggc ccgatggtcg aggtagaggc cgcgggcaag catcccggcc
     5461 tcgaccgccc ggtacaccca cccgtccgca tccaccgcgc cttgtgtgaa cacccaggtg
     5521 tgcacggcct ccaggacggc cttgcgggcc gcttccgccg ggtcgtaccg gcaggcgaac
     5581 cccgccgcgt acataccgcg cccgggatcg tgcacgaggg ccgcgacgca gggggcgaac
     5641 tcggagggca tctccacgat gtgcacgtcc aacgcgcagc cagccaggtc ctcggtgagt
     5701 ccggggacac tcgccgggtc gatgccgcgg gtgggtccgt ccaggtgcca ccacagctcc
     5761 agcgcgtcac gctcgacgac ttcgaggagc ccgcgctcga cggcgtcgtc gaggccctgc
     5821 ccggtggcga tgcccgcgta gttgaggtgg tgggtgcggg gcagcgaacg cagctccccc
     5881 tgacgccagt tgagatgggt cagggcgacg ggggcccagc agagctcccc gttctcgacc
     5941 gcccgggtcc acagcgccgg tgtgtcaggg acgagttcgg cgtacgggaa gcccgggcgg
     6001 ccgtactgcc acggtgcgta cgccgggagc gcgccggggc cgtagaggcg ggaaccctcg
     6061 gcggtcagct cggccgcggt ggcgcgccgg ggctcctggg gttggccggg cggcgggagg
     6121 cggttgccgc agtagcgctc cacggcctcg gccaccgcgg cgatccaggc accccggggg
     6181 tcgccgaagg tggtgccgag cgagacccgg tcggcgggcc aggcgccgag gcggcgggcg
     6241 tcggcgacgt cggcggtcat cgcggtgtag cggggcggcg caccggcggg gtgctcgacg
     6301 ggggcgacgg cgcggacgat cccgctgacg gaatcgacga gggcttcgag gggcagggcg
     6361 ctggtcaacg gcatatctcc ggtacgggct cgacgtagcg gcgtcgggcg acgacgggca
     6421 ggtggagggc gctgccccgg gggttcacgg tgcggcggga ggggacgagc cggatggcgg
     6481 tgaccgggtc gtcgccggtg tgcggattgc gggcgtgggc ggggaagtgg tgtccggcga
     6541 tctcggcccg cagccgggtc ccggcgggca gcctgcgacc gagggtgccg agcggcacgg
     6601 tgatgtcggc ggcttcgccg ggcgggccgg tgcgccggac gatgccgaag gcgagcggat
     6661 cggcgcggcc ggacgggtcg agcgcggtca ggcgtacggc ccagtccgcc gagggggtgt
     6721 cggccgtgac cgcgatccgg gcgacggcgg cccctgccag gtcgagcggg cggggcagcg
     6781 gcggcgagag cagcaggcag cggtcggcat ggtcgccgtc gaccgggacg gcgaggtcgt
     6841 cggagcgcac ggggcgctgc gggtcggcgc tgaactcggc tccgtggagc agccgtagac
     6901 cggtggacga gccgaagggc cagcggcact ccgcctcggg agcggtcccg ggccgctggg
     6961 tgccgcgcac ccgggtggtg tgccaacggc cgctgtcgcc aagggcgatg acgccgtgcc
     7021 gtgtcggctc caggcgcgcg gcgagcgcgg cgcgggccca ccgtacgtac agcgcaccga
     7081 ggttgacacg cgcgcgggcc ggagcggtcc ggtcggcggt gaggcggtgc ccccagggtc
     7141 cgagcagcag tcgcgccggt ccgccccagc cgcgccagag ggccacggtg tcctcggcga
     7201 aggggtcgcg ggtgccgccg acggcgagca gaggaaggcc gacggaggag ccgagcgcga
     7261 tgaggcggcc gcgttcccgg tcggcccaga gccggggcca ggacggcagt tcacgctcga
     7321 gacccgtggc catccgctcc gccagacggg cgaccggcag gtgttcgagc aaccgggggt
     7381 cgtcggccag ggcgcgttcc agggcgtcgg ggtcggagtc gcgccggtcg ccgtgggccg
     7441 cccaccagcc ggcccgggcc cacaatcgct ccgggccgcc gggctcacgc gcggtctcgc
     7501 tgagcccgag cgcgggaacg gcggcgatga ccgcgtcggg gattccgtcg ccttgcacca
     7561 cgccgggggc tgcgtcgggg tcgtcgagtg cggtgacgag ggcgcagtac gcggcgtagg
     7621 aggcgccaac ggcgacgacc tccccgttgc tccacgcctg tgcgcgcacc caggcgaccg
     7681 tggccgcgcc gtccgccttc tcctgatcct ggtacggatg ccactccccc ggtgaaccgt
     7741 ggcggccgcg tacatcctgg gcgagggcgg cgaatccgtg tgccgcccag ccgcgcagct
     7801 cggcgcggtg ggcctcgcgc ccgtacgggg tgcggatcag gacggcggga cgcgggcggt
     7861 ttccgtccgg gaggcagacg tcggtggcga gcggggtgcc gtccggcgcg gggacggaca
     7921 cggtgcgggt gttcacgcgc gggcctcggc ggcgctctcc ccggcgcgcg tccccaccgg
     7981 ggccggcacg ggcagcggcg cgacgtccgg gacgggaagc acggggtgct cggtgaaggt
     8041 gagatcgcgc agatcgatcc ggcgcagccg acggcggggc ggaagaccgg ccggctgccg
     8101 ccccaccccg cccgcagctt cggcttcggc ttcggcttcg gcttcggctt cggcttcggc
     8161 ttcggcttcg gcttcggctt cggcttcggc ttcggcttcg gcttcggctt cggcttcggc
     8221 ttcggcccag gcaatcaggt cggcggtgag cagggcggcg atcagggcgg cggacgcttc
     8281 ggtggggtgg ggacccgtgt cgggggtgcg gtgtccggcc cagtacgcgg cgagttcgcg
     8341 atgggcgggg gtggccgcga gtctacggag gcggacatgc cgggaggtga cgtctcccgg
     8401 ggccgcggca aggggctcga tccagctgtg cgagccctcg cggtgactgc gcagccaggc
     8461 gatacgccgg tccggcagcc ggtccgccgt gtcccagagc ccttcgggca cgggcgagtc
     8521 caggcaccac accacggcga cacacccttc ggggcggccg cggtccggga cggcgcgggc
     8581 cagctccgcg acctggtcgg gcgtgatgcg gcggacctcg gccccttccg ccccggcgca
     8641 gcgagccaca ggcccggtga gcacggggtc gccgaggaca tggacggtgc ggccggcgag
     8701 cggagcccgg ggcggaacgg acaccgcgtg cccaccggcc tcgaacgcct ccacgagcct
     8761 aacgagttcg gcggtcagcg gctcttcggc cgacggctgc ccgcccggcg cttcctcgcc
     8821 cgccagccga cgcaccagcg cttccccggt gacgccacgg gtgtcgatgc gcaggaactc
     8881 ccctccggag gtccggagca cgggggcggc gccgggaacg gtgacgatcc cggtgccggg
     8941 agcgagtcga ctgcgggtca cggaatcctc cgggtcggaa aggaaggggg aagacgggga
     9001 cggaatgact ggggccgaac ggggcgggcc cgcccgggtt gtcaccgggc gggcccgccc
     9061 ccgcgccacg cgggagacct gccttcagcg gcaggagtcg cttacttctc ggccgcggtg
     9121 tcggcctcga cggcgtcgtc gaaggggttc tcgacgaggg cgttcgagtg ggtggcggag
     9181 aggtgggcga gctggccctg gtcggcgatc gggctgaaca ccttgttctg ctccatgagt
     9241 tgaagcctcc attcagatcg gatgggtgtg ggtcgcggcg ttggtgcgtg ccgtagcaca
     9301 gacactaatg aatatgattt tcattccgca atagctggag tggatcgaga gggtgatctg
     9361 ggtaacagac gggccagccg ccctcgtcgt cgatccccac ccggccgtcc acgccgagga
     9421 cttcggccag gaggtgccgg gtgaccacct cggccggggg cccgtcggcg gcgatgcggc
     9481 cttcccggag cgcgacgatc cgatcggcga accgggcggc gtggttgagg tcgtgcagca
     9541 ccagcaccac cgtcagccgg cgttccgcgc gcagccgtac gaccgtctgg agcacctcca
     9601 gttggtgccg caggtcgagg taggtggtcg gctcgtcgag gaacagcacg ggggcgtcct
     9661 gggccagcgc catggccagc cggacacgct ggcgttcgcc tccggagagc gcgtccacgg
     9721 gccggtcggc ccagccggtg acgccgacgt ccgcgagcgc ccgggatgtc acctcgtcgt
     9781 cgccctcccg cagcatcccg agcggccccc gggcggcata gcgcccctgc cgtacgagtt
     9841 gacgcacggt cagcccgggt acggagggcg ccgactggtg cagcagcgcc acgcgccggg
     9901 cggcggtgcg gcggggcagt cgcgccacgt cgtcgccgtc gagcaggaca cgcccgccgc
     9961 tcggggtgag cagtccggcg gcgagtttga ggaaggtgct cttgccgcat ccgttcagcc
    10021 cgatcagggc gaccagttca ccggcccgga tgctcaggtc caccccgcgc agcaccggac
    10081 gtccggggta gccgaaggcc agcccctccg cccggacgac gtccggggtt ctcggtgtcg
    10141 cactggccat cgcgctcttc tccactgttc tctcccttgc tctctccctc atctctcgtc
    10201 cgcccgtcgc cgtgccacga ccatcagcag ccccgccccc acgcaggtgg tcagggcgcc
    10261 gaccgggagg gtcagccggt ccgcgtcgag cgccgtcgcc agcagccggg acagcagctg
    10321 tgccgcggcg tccgccccgc agaccaccgc ggcaccgagc agcgcggcgc ccggaagggt
    10381 gacgcggaga tcggctccga agacggccag cgccagatgg ggcaccagga gcccgacgaa
    10441 tccgagggcg cccacggccg acaccgcgcc ggccgtcagc gccaccgcgc acacgagcgc
    10501 cgctccccgt ccccgaccgg tggccagacc cgctgcggcg gcctgttcgt cgccgcagcg
    10561 cagcagcgtc aggggcccgg cgagcagcca ggccgccgcg ccccagatgg cggcccacgg
    10621 ccagagcaga ttccagtgct gccagacccg gccctcggtg gagccgatca accactggac
    10681 gacgctgccg agttcaccgg gggccaccag gaggacgacc gcggtgagtc cggcgagcac
    10741 cgccgacacg aggaccccgt agacggcggt ctgttccggg tcgccccggt cccgcccggc
    10801 gagcagccac agcagtcccg ccccggcgaa gccgccgacg caggccgcga cgaccacagc
    10861 cgtgggggac tcccaccccg cgaggccgag gccggtcgcg gtcaccgcgc cgagcaccgc
    10921 gccgggcgtg acgccggtga cctcgggtcc ggccagcggg ttgcgcaggg cggactggag
    10981 cacgagcccg gccaccccga ggcaggcccc ggcgaccagg gccaccagca tccggggcaa
    11041 gcggagttgg agcacgatgt gctcggcggt ggggtcgccg ccggccccga gcagcacggc
    11101 acgtacgccc tcgggggtga cgccccggcc ggcaaagagt ccggcacagg cgacgacggc
    11161 gacgagcagc gtcaggccgc cgatccggac acccggtgcg cgcagagccc ggcgggccgg
    11221 gacaggcgcg gcatcgacga aggtcatcgt tccgccttcc gcagcacggg agcggggacg
    11281 tccggcgacg tcaccggtgc gggcagggga acgggtcccc gggcccgggc gggccgtctc
    11341 ccccgtttca gcaggaggac cccgaccg
//
