LOCUS       NZ_CP029254            22256 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Streptomyces spongiicola strain HNM0071 chromosome, complete genome.
ACCESSION   NZ_CP029254
VERSION     NZ_CP029254.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces spongiicola
  ORGANISM  Streptomyces spongiicola
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7180417)
  AUTHORS   Zhou,S. and Huang,X.
  TITLE     Complete genome sequence of the Type Strain of Streptomyces
            spongiicola HNM0071, the producer of staurosporine
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7180417)
  AUTHORS   Zhou,S. and Huang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2018) Institute of Tropical Agriculture and
            Forestry, Hainan University, No 58, Haikou, Hainan 570228, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: ABySS v. 2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 850.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003122365.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 01:04:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,008
            CDSs (total)                      :: 5,921
            Genes (coding)                    :: 5,739
            CDSs (with protein)               :: 5,739
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 182
            CDSs (without protein)            :: 182
            Pseudo Genes (ambiguous residues) :: 0 of 182
            Pseudo Genes (frameshifted)       :: 47 of 182
            Pseudo Genes (incomplete)         :: 161 of 182
            Pseudo Genes (internal stop)      :: 9 of 182
            Pseudo Genes (multiple problems)  :: 32 of 182
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:10:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6963932
            Orig. end                         :: 6986188
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029254.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22256
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="28"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22256
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22256
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12256](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12256)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(292..306)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     misc_feature    complement(507..521)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     misc_feature    complement(1077..1087)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(1530..3248)
                     /locus_tag="DDQ41_RS30255"
                     /old_locus_tag="DDQ41_30255"
     CDS             complement(1530..3248)
                     /NRPS_PKS="Domain: AMP-binding (8-438). E-value: 5.8e-64.
                     Score: 208.1. Matches aSDomain:
                     nrpspksdomains_DDQ41_RS30255_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890864.1"
                     /locus_tag="DDQ41_RS30255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30255"
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_262508623.1"
                     /sec_met_domain="AMP-binding (E-value: 4.4e-68, bitscore:
                     228.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYNLADLFESVVDVVPDREALRYVDHPGTGARRMLSYAQLDAAA
                     NRVAHHLAGAGLKPGEHLGLHLYNGVEYLQTLLGCLKARIVPVNVNYRYVEDELVYLFR
                     DADLAALVFDAEFTGRVAAALPRTEKLRHLVRVGEPERDAPALDCTAFRAAEESGSPER
                     GFGERSADDRFIIYTGGTTGMPKGVLWRQEDLFFAGLGGGAPTGEPVRRPEELAERVAA
                     GGGGLTFFPTPPLMHGTSTLTAFIGFGFGQRVVLHRKYVPEEVLRTIERERVTSVSLVG
                     DAMLRPLVDALNGPLKGTDLSSLFSVSSSGAVMSETVREQFRTLAPHVMLLDNFGSSES
                     GFNGTATEDSGPGRGMRLRVNHRTRVVDPVTHEPVEPGRPGRIAQRGHVPLGYYNDPAK
                     TGETFFRRGGERWVLLGDMATVDGEGVVTVLGRGSQCINTGGEKVYPEEVEQALKAHPD
                     VYDALVAGVPDARWGNHVAAVVQLRPGAAALDLESVQAHCRGRLAGYKIPRQLVLAPVI
                     RRSPSGKADYRWAREVASAATGTATATGTGTGTGTRTGSGSGSGSGSGSGSGSEA"
     aSDomain        complement(1935..3224)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DDQ41_RS30255_AMP-binding.1"
                     /evalue="5.80E-64"
                     /label="DDQ41_RS30255_AMP-binding.1"
                     /locus_tag="DDQ41_RS30255"
                     /protein_end="438"
                     /protein_start="8"
                     /score="208.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FESVVDVVPDREALRYVDHPGTGARRMLSYAQLDAAANRVAHHLA
                     GAGLKPGEHLGLHLYNGVEYLQTLLGCLKARIVPVNVNYRYVEDELVYLFRDADLAALV
                     FDAEFTGRVAAALPRTEKLRHLVRVGEPERDAPALDCTAFRAAEESGSPERGFGERSAD
                     DRFIIYTGGTTGMPKGVLWRQEDLFFAGLGGGAPTGEPVRRPEELAERVAAGGGGLTFF
                     PTPPLMHGTSTLTAFIGFGFGQRVVLHRKYVPEEVLRTIERERVTSVSLVGDAMLRPLV
                     DALNGPLKGTDLSSLFSVSSSGAVMSETVREQFRTLAPHVMLLDNFGSSESGFNGTATE
                     DSGPGRGMRLRVNHRTRVVDPVTHEPVEPGRPGRIAQRGHVPLGYYNDPAKTGETFFRR
                     GGERWVLLGDMATVDGEGVVTVLGRGSQCIN"
     CDS_motif       complement(2679..2729)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DDQ41_RS30255_0001"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="DDQ41_RS30255"
                     /protein_end="190"
                     /protein_start="173"
                     /score="17.8"
                     /tool="antismash"
                     /translation="FIIYTGGTTGMPKGVLW"
     misc_feature    3348..3362
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.08"
                     /tool="antismash"
     misc_feature    complement(3352..3367)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.03"
                     /tool="antismash"
     gene            3422..4222
                     /locus_tag="DDQ41_RS30260"
                     /old_locus_tag="DDQ41_30260"
     CDS             3422..4222
                     /NRPS_PKS="Domain: ECH (9-258). E-value: 5.8e-51. Score:
                     165.1. Matches aSDomain:
                     nrpspksdomains_DDQ41_RS30260_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016467573.1"
                     /locus_tag="DDQ41_RS30260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30260"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_109297319.1"
                     /transl_table=11
                     /translation="MAGTEHLTVRREGATLVLTLNRPEARNALSLPMLVGLYDAWLEAD
                     ADDGVRSVVLTGAGGSFCAGMDLKALAGNGMEDEGYRDRLRADPDLHWKALLRHHRPRK
                     PVLAAVEGPCVAGGTEILQGTDIRVAGESAVFGLFEVRRGLFPIGGSTVRLPRQIPRTH
                     ALEMLLTGRPYTASEAERIGLVGSVVPDGTALERALGIAERVNACGPLAVEAVKASVYE
                     TAEMTETEGLAAELIRGWPVFDTADAKEGARAFAEKRDPEYRRA"
     aSDomain        3449..4195
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DDQ41_RS30260_ECH.1"
                     /evalue="5.80E-51"
                     /label="DDQ41_RS30260_ECH.1"
                     /locus_tag="DDQ41_RS30260"
                     /protein_end="258"
                     /protein_start="9"
                     /score="165.1"
                     /tool="antismash"
                     /translation="RREGATLVLTLNRPEARNALSLPMLVGLYDAWLEADADDGVRSVV
                     LTGAGGSFCAGMDLKALAGNGMEDEGYRDRLRADPDLHWKALLRHHRPRKPVLAAVEGP
                     CVAGGTEILQGTDIRVAGESAVFGLFEVRRGLFPIGGSTVRLPRQIPRTHALEMLLTGR
                     PYTASEAERIGLVGSVVPDGTALERALGIAERVNACGPLAVEAVKASVYETAEMTETEG
                     LAAELIRGWPVFDTADAKEGARAFAEK"
     gene            4525..5742
                     /locus_tag="DDQ41_RS30265"
                     /old_locus_tag="DDQ41_30265"
     CDS             4525..5742
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982027.1"
                     /locus_tag="DDQ41_RS30265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30265"
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="WP_109297320.1"
                     /transl_table=11
                     /translation="MSATPASATPASGAPSSPEVPRAPLVVEFPFTRSLGPVQSAFLTG
                     LRERTVLGVRTTGGRVLVPPVEYDPETSEEIGDLVEVGTTGTVTTWAWNPDPRRGQPLR
                     TPFAWVLVRLDGADTGLLHALDASGPDAVRTGMRVRVRWAAERGGSITDIACFEPYRDG
                     PESGAESGPESGGEGSPGRGSESGAEHRDDDPAEHRGPGNGTGSGTGSGTGRATRSGTG
                     SGTRSTEPATPGAEGRAATGPRSHSGEFDDPVTGVVVPARLDYTYTPGRAQTRFISALA
                     ERRTTGERCPSCRKVYVPPRGACPTCGVATSEQVEVGPRGTVTTFCIVNIKAKNLDIEV
                     PYVYAHIALDGADLPLHGRIAGIPYDRVRMGLRVEPVWTGDDRHPDHYRPTGEPDADYD
                     TYRELL"
     gene            5745..6797
                     /locus_tag="DDQ41_RS30270"
                     /old_locus_tag="DDQ41_30270"
     CDS             5745..6797
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890861.1"
                     /locus_tag="DDQ41_RS30270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30270"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_109297321.1"
                     /transl_table=11
                     /translation="MRDVAIVAFSQTDHVRSSEEVSEVEMLMPVLHDVLGRTGLRTGDI
                     GFTCSGSCDYLAGRAFSFTMALDGVGAWPPIPESHVEMDGAWALYEAWVKLLTGEADTA
                     LVYAYGKSSPGSVRDVLTRQLDPYYLAPLWPDSVALAALQAQALIDSGETDEPALAAIA
                     ERSRTAAEGNPHAQLRGPRPQGGYVVRPLRTGDCPPVGDGAAAVVLAAGDRARELCPRP
                     AWIRGMDHRVEPHALGVRDLTDSPSTRLAAERAGVHERPVDTAELHAPFTSQEVVLRKA
                     LRLGDSVAVNPSGGALAANPVMAAGLIRVGEAAAAVHRGASGRALAHATSGPCLQQNLV
                     AVLEGEPHAR"
     gene            6787..7956
                     /locus_tag="DDQ41_RS30275"
                     /old_locus_tag="DDQ41_30275"
     CDS             6787..7956
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262476.1"
                     /locus_tag="DDQ41_RS30275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30275"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_172607586.1"
                     /transl_table=11
                     /translation="MPAKEPVAVVGVGQTKHVAARRDVSIAGLVREAARRALDDAGLGW
                     AGIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPLMRVHTAGSVGGSTALVAAGLVAA
                     RVHRTVLTLAFEKQSESNAMWGLSLPVPFQQPLLAGAGGFFAPHVRAYIRRSGAPGTVG
                     CLVAYKDRRNALRNPYAHLHEHDVTLEKVRSSPMLWDPIRYSETCPSSDGACAMVLADR
                     AGAARAPHPPAWVHGGAMRSEPTLFAGKDFVSPQAGKDCAADVYRQAGITDPRREIDAV
                     EMYVPFSWYEPMWLENLGFAAEGEGWKLTESGVTELDGELPVNPSGGVLSTNPIGASGM
                     IRFAEAALQVRGRAGAHQVAGARKALGHAYGGGSQFFSMWLVGAEPPEA"
     gene            8165..8407
                     /locus_tag="DDQ41_RS30280"
                     /old_locus_tag="DDQ41_30280"
     CDS             8165..8407
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890859.1"
                     /locus_tag="DDQ41_RS30280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30280"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_109297323.1"
                     /transl_table=11
                     /translation="MADIITTEQPLAGWDKPDLDLSQADWQSGSQGAGDVQIAFVEGFI
                     AMRNGGRPEGPSLIFSPAEWRAFVMNARHGEFDLT"
     misc_feature    complement(8166..8180)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.19"
                     /tool="antismash"
     gene            8574..8972
                     /locus_tag="DDQ41_RS30285"
                     /old_locus_tag="DDQ41_30285"
     CDS             8574..8972
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158014.1"
                     /locus_tag="DDQ41_RS30285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30285"
                     /product="ACT domain-containing protein"
                     /protein_id="WP_109297324.1"
                     /transl_table=11
                     /translation="MAPEHDLGRLLSGMRPELHPGRYVFTTVPASVPPGLTPVATVTED
                     EGLTLVVRREEADGAGLAYDYVAGWITLRVHSALAAVGLTAAVATALAGAGIGCNVVAG
                     HHHDHLFVPYERADESVALLQGPAERAG"
     gene            9143..9643
                     /locus_tag="DDQ41_RS30290"
                     /old_locus_tag="DDQ41_30290"
     CDS             9143..9643
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="DDQ41_RS30290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30290"
                     /product="hypothetical protein"
                     /protein_id="WP_109297325.1"
                     /transl_table=11
                     /translation="MSFLRRRSASTPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLFGGRGPAMIIGNLPEGSPARDVAEGEAPFEVAQLLAALEDDEEVTVVGAEDV
                     PVMQGDNLLIVRRVKLSQGRISCVQFDRSDNVLVTIASWDRPITDDLYALLKPLPAELF
                     QQG"
     gene            complement(10001..12256)
                     /locus_tag="DDQ41_RS30295"
                     /old_locus_tag="DDQ41_30295"
     CDS             complement(10001..12256)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948349.1"
                     /locus_tag="DDQ41_RS30295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30295"
                     /product="Geosmin synthase"
                     /protein_id="WP_109297326.1"
                     /sec_met_domain="T1TS (E-value: 1.4e-84, bitscore: 283.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFELPDFYVPHPARLNPHVDAARRHTREWARRMGMLEGSGVW
                     EPEDLEAHDYALLCAYTHPDCSAETLSLVTDWYVWVFFFDDHFLEVFKRPRDIAGGSAY
                     LERLPAFMPPDPGQGVPEPANQVEAGLADLWRRTAPGMSEAWRARFAEATEHLLNESLW
                     ELRNIDRGRIANPVEYVEMRRKVGGAPWSAGLVEFAAGAEVPERVAGSRPMRVLRDAFS
                     DGVHLRNDLFSYEREVGDEGENSNGVLVLEKFLGCSTQEAADAVNDLLTSRLQQFENTA
                     LTEVPALCAERGLDPAECAAVAAYAKGLQDWQSGGHEWHLRSSRYMNEGAVAGPSMFEG
                     VLGTSALDVRTLFGRPAAARLRALTHVPHQATGPSLLPEFDCPFPLSLSPHHEEARSRS
                     IAWAKRMGLLGDVWDEAMLNGFDFALCSAGIDPDATAEELELSAEWLTWGTYGDDYYPL
                     VFGRRRDLAGAKACTDRLAACMPLDDPASGAAVAVSPMERSLADLWARTAGPMGPGARA
                     GLRRAMDVMLESWLWELHNQAQHRVPDPVDYLEMRRCTFGSDLTMMLSRLRHEGELPPE
                     IYGTGVMRSLENSAADYACLLNDFFSYQKEIEVEGEVHNALLVVQNFYGCDYRAAVGIV
                     DDLMRSRMSQFLHVKEHELPLLHEQFSLDSRGRAALGAYVRELEDWLAGILNWHRKARR
                     YGVEDVRSGAGSALRVDGPLALGMSAADLAGLLRSGGGTGAGEPFPGVGAAAGAVRL"
     misc_feature    12240..12255
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.04"
                     /tool="antismash"
     gene            complement(12404..14311)
                     /locus_tag="DDQ41_RS30300"
                     /old_locus_tag="DDQ41_30300"
     CDS             complement(12404..14311)
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948350.1"
                     /locus_tag="DDQ41_RS30300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30300"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_109297327.1"
                     /transl_table=11
                     /translation="MVAALLLTLASGAPSATAEQSAPSGGLQRAFADAAAEYRVPQNVL
                     LGVSYIQSRWDGHGGAPSVTGGYGPMHLTDAATALAEAPHHSHGAEDPRGDTARVPRTG
                     GAHALGERAVFPARLRTLERAADLTGIPAERLRTDPSANVRGGAALLADAQRELGGAPG
                     GGAADWFGAVARFSGADDTATATAYADDVFDVIRTGQSRTTDGGQRVSLRADGGPPPDR
                     SAVARLGLRTADRTLTECPVTVACEWIPAPYEQFGEGDYGNHDKADRPVSQSVEYIVIH
                     DTEATWDTTLRLVQDPEYVSWHYSLRSSDGHVAQHLRLKDVGWHAGNWFINAKSIGLEH
                     EGFLVSPDAWYTEAMYRSSARLVRHLAGRYGVPLDRQHIIGHDNVPGTLPSTVPGMHTD
                     PGPYWDWAHYFTLLGRPFAATAGPGAAAVTIRPDYDRHRPVYTGCAEAGGGCAPHGSGA
                     VRLHTAPDASSPLVKDAGLRPDGGDSTTGVNDTGARASTGQRYAVAERRGDWTAVWYLG
                     GKAWFHNPRTRPVAVGAHAVLVTPRAGLAEVPVYGRAYPEASAYPPGVPVQAVTPLPYK
                     LLAGQRYVTAGSMPGEYYRATGFDASQHTVVRGEERYHVIQFGHRVAFVKAADVLVTRR
                     "
     gene            complement(14683..15570)
                     /locus_tag="DDQ41_RS30305"
                     /old_locus_tag="DDQ41_30305"
     CDS             complement(14683..15570)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892948.1"
                     /locus_tag="DDQ41_RS30305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30305"
                     /product="universal stress protein"
                     /protein_id="WP_109297328.1"
                     /transl_table=11
                     /translation="MARCITAGVDGSPESRAAAYWAAREAALRGLPLRLVHAWLWQPLD
                     VPIVQDREAQARAAESLLREAESEISRRFPDVPVSAEVVPDTAVAALVGEAERATMLVL
                     GSRGHGAVVGFLVGSYGQQVIASASCPVVAVRAPAGEDRAADPEPGGGDEIVVGQQGAP
                     EDCEAVLGFAFETAAAHGVGVRAVRAWSLPTLYTYSPAAMRLADEAGGLEPFERKALSE
                     ALKPWRDRYPGVPVTEHVEIGSAGQVLLSATARARLLVVGRRARRSPVGSRIGSVAHAA
                     LHHAPCPVAVVPPV"
     gene            complement(16061..17179)
                     /locus_tag="DDQ41_RS30310"
                     /old_locus_tag="DDQ41_30310"
     CDS             complement(16061..17179)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="DDQ41_RS30310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30310"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_109297329.1"
                     /sec_met_domain="APH (E-value: 9.2e-18, bitscore: 63.5,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRPRTLQAGGGPLLEPSAAGRARRWPGAVGQPLS
                     GRIDLSGPQGAQLRMAIASVHRICPEFNPVQVLRRSGRSVLLVGTTGRTTAVAKCLLDQ
                     SPAWAERFRHEIAAYRAFVRHRPPVRVPRLIAADPENCTLVVERMPGRPAALARHPSEA
                     PPRADVRAALGAVARLNSWRPPSGMFDAPLDYVSRFARYHELGLFTDRDLGDLQKLLHG
                     LAHHGGRQGGLGQFCHGDALLSNILLAPTGPVLVDWEHAGWYLPGYDLATLWTVLGDAP
                     VARRQVSQLAQQSGPAARDAFLVNLMLVLTREIRTYETAVQRTMREAPPAGTVPPPHTG
                     LSSGEEQRLLLRRLHDDCALARRAVRAAVGTR"
     misc_feature    complement(16877..16879)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17412..18905
                     /locus_tag="DDQ41_RS30315"
                     /old_locus_tag="DDQ41_30315"
     CDS             17412..18905
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948353.1"
                     /locus_tag="DDQ41_RS30315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30315"
                     /product="hypothetical protein"
                     /protein_id="WP_109297330.1"
                     /transl_table=11
                     /translation="MTGVPNTRLADLFGLAGWSKGELARLVNRQAAAMGHAQLATDTSR
                     VRRWIDMGESPRDPVPKVLAALFTERLGRVVTIEDLGFVRHGRTRKRREAGGVGHPDGL
                     PWAPERTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSALSSAMYDWLHTDPALATHAPR
                     VHDPLHADPAGFDRYEAAPIGSQEIDALERSVEVFRAWDASRGGGLQRKAVVGQLNEVG
                     GMLAYRHPDHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLARSGSGESTLPRTRAMLHTIEAWAQASMGRAQA
                     MRRTLGEAEELFVSDKGDVPPPSWMQMFDEADMHGMQALAYRTLAEHDPAAAGIAQRHA
                     KQALELREGGRQRSKIFDYISMASACFIADDPEQADRYARLALVSMGETSSHRTWDRLR
                     EMYRLTGQFAGYAKIEDLREEIQHALPNSPSRSERSVRI"
     gene            complement(19258..20703)
                     /locus_tag="DDQ41_RS30320"
                     /old_locus_tag="DDQ41_30320"
     CDS             complement(19258..20703)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948354.1"
                     /locus_tag="DDQ41_RS30320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_30320"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_109297331.1"
                     /transl_table=11
                     /translation="MPSHLFADRPAPQPPRRDSVDELISQTRRLRGDVDAVRRDAVVDE
                     DDPQGRWQRALCDLAVHQLDDLGAHLGQLREGLPPLPGPDGPPGREDQAGFEDLPPRPD
                     SLLSRVGSAEWNLLTDEVSWSEELHRIFGRPAAGDPMTLDELPSMVFAEDQALLTEMVT
                     DCLVDGKPIDGEFRIVRADGRVRTLHMTGEPVLDADGCTASMWAVLRDVSELRRSQRAV
                     RESQDTLTRRQHIDRTERRVATQMHEAVLPPWRGERSIPANGPAALDLAGHHLPSPRGA
                     LNGSQWFDAQEIPGGLALLSVGDLTGQGVTATSAMAMLMGAQRALAVAGIRPGPLMGHL
                     NALLDSAAQPALGSTVCCHYDPSTRILSWAQAGHPAPLLYRGGVGRALPRPGGVLLGAT
                     AGGVYEQGETALLPGDVLVLHTDGLTRGTGAPHDSTGHDRLLALAPRLTVARSAQDCVR
                     LIVEEFDVGDRQHDASVMVARIA"
     misc_feature    complement(20233..20235)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 ccagcccggc caccagccgc tgcacatccg ccttcggccg caccacgagg cgaaggaagc
       61 tgctggagct gcctatcttg ttgccgcact cccgcaccag tacgccgtgc tcctccagca
      121 tccggttcct cagcagggcg ccgtcggcgc cctccgggag ccgtacgtac acgaagttgc
      181 cctgggacgg gtacacggtg agcccgggca gccggctcag gtgccagatc atctcctggc
      241 ggtcgcgctg caccagccgc aggctgtgcg cgtactccat ccggtactcc ttgagcatga
      301 acaccaccgt ttcggcgaag gagttgaggt tccacttcgg cagcgccgcc cgcacccggc
      361 ccgcgaggcc agggttggcc acgaggtagc cgaagcgcac cccgtgaagc ccgaagttct
      421 tgcccaggct cctcagcacc acggtgttgg gccgcagcac cgcgtcggcg acgacgctgg
      481 agtccgtctc ggcgtcggcg aactccagga acgactcgtc cacgaccacc aggtccaggt
      541 cctggagctg gtcgagcaga gcgaggacgc cgtgccgcgg cagcagaccg ccgtcagggt
      601 tgttcggatt gcagatgacg gcggtccggg agccgcgcgc gcggatgaag tcgacgaacg
      661 acgccgggtc gagcgcgaat ccgctgggct cgggcagcgg gaacatgtcg acccgcttgc
      721 ccgtctccat cggctggtcc gtccaccggc cgaaggtcgg caccggcacg gccagcgact
      781 cgcgcaccag cagatggtcg atccaggtga tcagttcggt ggagccgttg cccatggcca
      841 cggtctgcgg gttgagaccc agcacggagc acagctccgc ggtgatggtg tccgcgctgc
      901 tggggtagta ggtgaggatg tcccgcagcc ggtctcccag ttcgtcgaac atctccggtg
      961 gggggaagta cgggttgcac gggatacaga agtcggtgat cggctggtgg tcgccggtgg
     1021 cccggctcag cgcggcgtac gacgggctgt gtgccgtgga cgcgcggaag agctcggtga
     1081 cattgctgcc ggcttcggcc atgggggtcc tccggaggtg gcttggtgct ccctgccggg
     1141 gattacgtac gagtgatcgg ccgtgctcaa cgggatcgag ccacagggcc cacgggacgg
     1201 ggcgggcgtc tcccgggacg ggccgggggc ggttcgcctc cggccggtga cgtgccgact
     1261 gccgcctccg accggtgact tccggtcccg ccgtctgccg tcgggccgtc ccgccgtccg
     1321 gccgtccggc cgtcccgccg tcccgccgtc cggccgtccg gccgtcccgc cgtcccgccg
     1381 tccgccgtcc ggcgccgggc gggcgttggt cgccctcggc cgccgggtcg tccggccgcc
     1441 aggcgggaac cttccgcggt gcccgctcgg tctgcttcgc cccggtgccg ccgggggccg
     1501 agacggccac ccggtgtccg ccgggttcac tacgcctcgc tgccgctgcc gctgccgctg
     1561 ccgctgccgc tgccgctgcc gctgccggtg cgggtcccgg tcccggtccc ggtcccggtg
     1621 gcggtggccg tcccggtggc agccgaggcg acctctcgtg cccagcggta gtcggccttg
     1681 ccgctcggcg agcgccggat gaccggtgcg aggacgagct gccgagggat cttgtacccc
     1741 gccagccggc cgcggcagtg cgcctggacg gactccaggt ccagcgcggc cgcccccggg
     1801 cgcaactgca cgaccgcggc cacatggttg ccccacctcg cgtcgggtac cccggcgacc
     1861 agcgcgtcgt agacgtccgg atgggccttg agcgcctgct cgacctcttc cggatagacc
     1921 ttctccccac cggtgttgat gcactgggac ccccggccga gcaccgtgac gaccccttcc
     1981 ccgtccaccg tggccatgtc gccgagcagc acccagcgct cgcctcccct gcggaagaag
     2041 gtctcgccgg tcttggccgg gtcgttgtag tagccgagcg gcacatggcc gcgctgggcg
     2101 atgcggccgg gccggccggg ctcgaccggc tcgtgtgtga ccgggtcgac cacccgtgtg
     2161 cggtggttga cccgcagccg catccccctg cccggaccgg agtcctccgt ggcggtgccg
     2221 ttgaagccgg actccgacga gccgaagttg tccagcagca tcacatgcgg agccagcgtc
     2281 ctgaactgct cccgcacggt ctcggacatg accgcaccgg acgacgacac gctgaacagc
     2341 gacgacaggt ccgttccctt cagcgggccg ttcagcgcgt cgaccagcgg gcgcagcatc
     2401 gcgtctccca ccagcgacac ggacgtgacc cgctcccgct cgatcgtgcg cagtacctcc
     2461 tcgggcacgt acttgcggtg cagcaccacc cgctggccga atccgaagcc gatgaacgcg
     2521 gtgagtgtcg aggtgccgtg catcagcggg ggagtgggga agaaggtgag gccgccgccg
     2581 cccgccgcga cccgctccgc cagttcctcg ggccgccgca ccggctcacc ggtgggagcg
     2641 ccgccgccga gtccggcgaa gaagaggtcc tcctggcgcc acagcacccc cttgggcatc
     2701 ccggtcgtac cgccggtgta gatgatgaac cggtcgtccg ccgaccgctc gccgaagccg
     2761 cgctccggcg agccggattc ctcggcggcc ctgaacgccg tgcagtccag cgccggtgcg
     2821 tcccgctccg gttcaccgac gcgcacgagg tgccgcagct tctcggtccg cggcagcgcg
     2881 gccgccaccc ggccggtgaa ctcggcgtcg aagaccaggg ccgcgaggtc ggcgtcgcgg
     2941 aagaggtaga ccagctcgtc ctccacatag cggtagttca cattgaccgg gacgatgcgc
     3001 gccttgaggc agccgagcag cgtttgcagg tactcgacgc cgttgtagag gtgcagcccg
     3061 aggtgttccc cgggcttcag ccccgcgccg gcgagatggt gggcgacacg gttcgcggcc
     3121 gcgtcgagct gcgcgtagct gagcatccgc cgcgcgcccg tgccgggatg gtcgacgtag
     3181 cggagcgcct cgcggtcggg aaccacgtcg acgacagact cgaaaaggtc ggcaaggttg
     3241 tactccaccg ctcctcctga ccccggccgc acggtgtccg cctcggagcg gtcattagag
     3301 cgccgccgtc cgcaactggg aaggggtacc gcccagaaaa tctgactgtc tgtcagaaaa
     3361 ctcttgaact gctccgctgg ctcctgcaac ctgttctagg tctcaggacg ggaggacggg
     3421 aatggcgggt acggaacacc tcaccgtgcg gcgcgaaggc gccactctgg tgctcacgct
     3481 gaacagaccc gaggcccgga acgccttgtc gctgcccatg ctggtggggc tgtacgacgc
     3541 ctggctggag gccgacgcgg acgacggcgt ccgctcggtc gtcctcaccg gcgcgggcgg
     3601 ctcgttctgc gccgggatgg acctcaaggc cctcgccggg aacggaatgg aggacgaagg
     3661 gtaccgggac cggctcaggg ccgacccgga cctccactgg aaggccctgc tccgccacca
     3721 ccgcccgcgc aagccggtcc tcgcagccgt cgagggcccc tgcgtcgccg gcggcaccga
     3781 gatcctccag ggcacggaca tccgtgtcgc cggcgagagc gccgtgttcg ggctgttcga
     3841 ggtccgccgg ggcctgttcc cgatcggcgg ctccaccgtg cggctcccgc gccagatccc
     3901 gcgtacccac gccctcgaga tgctgctcac cggccgcccc tacacggcct ccgaggcgga
     3961 gcgcatcggc ctcgtcggca gcgtcgtgcc cgacggcacg gctctggagc gcgcgctcgg
     4021 catcgcggag agggtcaacg cctgcgggcc gctcgccgtg gaggcggtga aggcgtccgt
     4081 gtacgagacg gccgagatga ccgagaccga ggggctggcg gccgaactga tccgcggctg
     4141 gccggtcttc gacaccgccg acgccaagga gggggcccgc gccttcgccg agaagcgcga
     4201 cccggagtac cgccgggcct gaccgctcgg cccgcccggt cgccccggcg gagccacccg
     4261 gccccgcggc accggcacct cgccggcccg cccggcgggc accacccggc gaggccgccc
     4321 ggccggcgta cccggcgacg ccgcccggct gctccgcgcg cggcagcacg gcacccgggt
     4381 accggcaccg gccctcccgg cgcaacgggc gcaacgggcg cgacctccgg cacggcacac
     4441 ggcacacggc acacggcaca cggcggacca tgcgcctgag cacgcggcag cacatccggc
     4501 agcacaagcg gcagaaggag tcccatgtcc gccacccccg cgtccgccac ccccgcgtcc
     4561 ggggcgccct cgtcaccgga ggtgccgcgc gccccgctcg tcgtcgagtt ccccttcacc
     4621 cgctccctgg gccccgtgca gtccgccttc ctcaccggcc tgcgtgaacg caccgtgctc
     4681 ggtgtcagga ccaccggcgg ccgggtcctc gtaccacccg tcgagtacga ccccgaaacc
     4741 tccgaggaga tcggcgacct cgtcgaggtg ggcaccacgg gcaccgtcac cacctgggcc
     4801 tggaacccgg atccgcgccg cggccagccg ctccgcaccc ccttcgcctg ggtgctggtg
     4861 agactcgacg gcgccgacac cggcctcctc cacgccctcg acgcctccgg ccccgacgcc
     4921 gtgcgcaccg gaatgcgcgt ccgggtccgg tgggccgcgg agcgcggcgg atccatcacg
     4981 gacatcgcct gcttcgagcc gtaccgcgac ggtcccgaaa gcggcgccga aagcggtcct
     5041 gagagcggcg gcgaaggcag ccccggaaga ggctccgaga gcggcgccga gcaccgcgac
     5101 gacgaccccg ccgagcaccg cggcccgggg aacggcacgg ggagcggcac ggggagcggc
     5161 acggggaggg cgacgaggag cggcacaggg agcggcacga ggagcacgga gcccgcgacg
     5221 ccgggtgccg agggacgcgc ggcgaccgga ccacgctccc acagcggcga gttcgacgac
     5281 cccgtgaccg gtgtcgtcgt cccggcccgg ctcgactaca cctacacgcc aggtcgcgcc
     5341 cagacccgct tcatcagcgc cctcgccgag cgccggacca ccggcgagcg ctgcccctcc
     5401 tgccgcaagg tgtacgtacc gccccgcggc gcgtgcccga cctgcggcgt cgccacctcg
     5461 gaacaggtcg aggtcggtcc acgcggcacg gtcaccacgt tctgcatcgt caacatcaag
     5521 gcgaagaacc tcgacatcga agtgccctac gtatacgcgc acatcgccct cgacggcgcc
     5581 gacctgccgc tccacggccg catcgccgga atcccgtacg accgggtgcg catgggcctg
     5641 cgcgtcgaac cggtgtggac cggtgacgac cggcaccccg accactaccg gcccaccggt
     5701 gaacccgacg cggactacga cacctaccgg gagctgctgt agccatgcga gacgtcgcga
     5761 tcgtcgcctt ctcccagacc gaccacgtac gcagcagcga ggaggtctcc gaggtcgaga
     5821 tgctcatgcc cgtgctccac gacgtcctcg ggcggaccgg gctgcgcacc ggggacatcg
     5881 gcttcacctg ctccggctcc tgcgactacc tggcgggccg ggcgttctcc ttcacgatgg
     5941 cactcgacgg ggtgggcgcc tggccgccca tcccggagtc gcacgtggag atggacggtg
     6001 cctgggcgct ctacgaggcc tgggtcaagc tcctcaccgg cgaggcggac acggccctcg
     6061 tctacgcgta cggcaagtcc tcgcccggtt cggtccggga tgtgctgacc cggcagctgg
     6121 acccgtacta cctcgcgccg ctgtggcccg actccgtcgc cctcgccgcc ctccaggccc
     6181 aggcgctcat cgactcgggg gagacggacg agccggccct ggccgcgatc gcggagcgca
     6241 gcaggaccgc cgccgagggc aacccgcacg cgcagctccg cgggccccgc ccgcagggcg
     6301 ggtacgtcgt ccggccgctg cgcaccggcg actgcccgcc cgtcggcgac ggagccgccg
     6361 cggtggtcct cgccgccggc gaccgggccc gggaactgtg cccgcgcccc gcctggatcc
     6421 ggggtatgga ccaccgcgtc gaaccgcacg ccctcggcgt gcgcgatctc accgactcgc
     6481 cctcgacccg cctcgccgcc gaacgcgccg gagtccacga gcggcctgtg gacaccgccg
     6541 aactgcacgc cccgttcacc tcccaggagg tggtactgcg caaggccctg cgcctcggcg
     6601 actccgtcgc cgtcaatccc tcgggaggcg cgctcgccgc caaccccgtc atggcggcgg
     6661 gcctcatccg cgtcggcgag gccgccgcgg ccgtccaccg cggcgcatcc ggccgcgccc
     6721 tcgcccacgc cacctccggc ccctgcctgc aacagaacct ggtcgccgtc ctcgaaggag
     6781 aaccgcatgc ccgctaagga gccggtggcc gtggtcggcg tcggccagac caagcacgtc
     6841 gccgcccgcc gcgacgtgtc catagccggg ctggtccgcg aggccgcgcg ccgcgccctc
     6901 gacgacgccg gcctcggctg ggccggcatc gacgccgtcg tcatcggcaa ggcccccgac
     6961 ttcttcgagg gcgtgatgat gccggagctc tatctggccg acgccctcgg agccgtcggc
     7021 aagccgctga tgcgggtcca cactgcggga tcggtcggcg gctccacggc gctggtcgcc
     7081 gccggtctcg tggcggcccg ggtccaccgg accgtcctga ccctcgcctt cgagaagcag
     7141 tccgaatcga acgcgatgtg gggcctgtcg ctgcccgtcc cgttccagca gccgctgctc
     7201 gcgggcgcgg gcgggttctt cgccccgcat gtgcgcgctt acatccgccg cagcggcgcg
     7261 cccggcaccg tcggctgcct ggtcgcgtac aaggaccgcc gcaacgcgct gaggaacccg
     7321 tacgcacatc tccacgagca cgacgtcacc ctggagaagg tgcggtcctc gccgatgctg
     7381 tgggatccga tccggtactc ggagacctgc ccgtcctccg acggggcctg tgcgatggtc
     7441 ctcgccgacc gggccggggc cgcccgcgcg ccgcaccctc cggcctgggt gcacggcggc
     7501 gcgatgcgca gtgaaccgac gctgttcgcg ggcaaggact tcgtgtcgcc gcaggccggc
     7561 aaggactgcg cggcggacgt ctaccggcag gccggcatca ccgacccgcg gcgcgagatc
     7621 gacgccgtcg agatgtacgt gcccttctcc tggtacgagc cgatgtggct ggagaacctg
     7681 ggcttcgcgg ccgagggcga gggctggaaa ctcaccgagt ccggtgtgac ggagctcgac
     7741 ggcgaactgc cggtgaaccc gtccggaggg gtgctgtcca ccaaccccat cggcgcctcc
     7801 gggatgatcc ggttcgccga ggcggccctc caggtgcggg gccgggcggg cgcgcaccag
     7861 gtggcggggg cccggaaggc cctcggccac gcctacggcg gcggctcgca gttcttctcc
     7921 atgtggctcg tcggcgccga gccgccggag gcctgagcgg cgcgcccggg ggaggcgcgc
     7981 cgcgggtgga cgaggagcgg ggcccggcgg ggcgcggtcg gccggcgggt gcggcccggc
     8041 ggggtgcggt cggccggtgg gtgcggcctg tttttccggc ggcgactccc gccgcggcgg
     8101 cctgtccgcg accggccccg atcgctacgc tgaccccgga cgaagaaccg ggaggagcag
     8161 ggacgtggcc gacatcatca ccacagagca gccgcttgcg ggttgggaca agccggacct
     8221 cgacctcagc caggcggact ggcagtcggg gtcccaggga gcgggagacg tgcagatcgc
     8281 cttcgtcgag ggcttcatcg ccatgaggaa cggcggccgc cccgagggcc cgtcactgat
     8341 cttcagcccg gcggaatggc gggccttcgt catgaacgcc cggcacggcg agttcgacct
     8401 cacctgatcc gcgcctccgg cggcggcccg cgtgcgatac gggatgggcc gccactccgg
     8461 atgccgacct tcgaagataa ggcgcagtgg cgaatccttc cctggttccc aggtccatat
     8521 cgccggtgag gggcgctccg ccgccggaag cacagaaccg caggctgcga atcatggcac
     8581 cagagcacga tctcggccgt ctcctgagcg gtatgcgtcc cgaactccac cccggccgct
     8641 atgtcttcac caccgtcccc gcgtcggtac cgccgggcct cacccccgtg gccaccgtca
     8701 ccgaggacga gggcctgact ctcgtcgtac gcagggagga ggccgacgga gccgggctgg
     8761 cctacgacta cgtcgccggc tggatcaccc tgcgcgtgca ctccgcactc gccgccgtcg
     8821 ggctcaccgc cgcggtcgcg accgccctgg ccggtgcggg catcggctgc aacgtcgtcg
     8881 ccggccacca ccacgaccat ctgttcgttc cgtacgaacg cgcggacgag tctgttgccc
     8941 tcctccaggg gccggccgaa cgcgcgggct gaggccacgg cgacggcccg tccgcccggt
     9001 cgacccgctg cggcgtgtcg cgcgggccgg ggggccaccg tgctcctgcg tgtcgcgcgg
     9061 ggcggggtca ccgcgctgcg gcgtgtcgcg ccgccgtgcg cccggtcggc ggcatcggct
     9121 cccgggcacg taccatgtcg gcatgtcctt cctccgccgc cgcagcgcct ccactcccgc
     9181 gggcccggac ttcgacgtcc tggccatgga cccgggggac tggcccggca atctgggagc
     9241 cgggctgctt cccgcgcccg acggcagctg ccagggcgtc ttcctgcgct acgacctgtt
     9301 cggcggccgg ggccccgcga tgatcatcgg caatctgccg gagggctccc ccgcccgcga
     9361 cgtcgccgag ggagaggccc ccttcgaggt cgcccagctg ctcgcggcgc tggaggacga
     9421 cgaggaggtc acggtcgtcg gcgccgagga cgtgcccgtc atgcagggcg acaacctgct
     9481 gatcgtccgc agggtcaaac tctcccaggg ccggatctcc tgcgtgcagt tcgaccgcag
     9541 cgacaacgtc ctcgtcacga tcgcgagctg ggaccggccg atcaccgacg acctgtacgc
     9601 gctgctgaag cccctgcccg cggaactctt ccagcagggc tgaccgaccc gcccgccgcg
     9661 gagcaccgca cacggagcgg accccgcgcg ggtgagtccg gcccgccggg tgtgggtctc
     9721 gcgcatccac tgctggcgcg gaccccgcga ggctgagtcc ggcccggggg tcccgccgaa
     9781 cctcgtgccg cccggtcctc accccgcccg gtcgtcgccc ctcccacccg tgcacgggcc
     9841 ccgtcccgga cgggggcacg gaggaccgca caccccgtcc gggccggggc accgcgtcgc
     9901 ggccccggcc cggacacgcc ggacgcatcg gacacgccgg acgcaccgga cacccggacg
     9961 cgcccgatgc ccaggtgcgc ccgacgccgg cgcgcgcggc tcagagccgc acggcgcccg
    10021 ccgccgcgcc cacgccgggg aacggttcac cggcgcccgt ccccccaccg gaccggagca
    10081 gaccggcgag gtccgccgcc gacatcccca gtgccagggg cccgtcgaca cgcagcgccg
    10141 acccggcgcc cgaccgcacg tcctccactc cgtaacggcg cgccttgcgg tgccagttga
    10201 ggatgcccgc gagccagtcc tccagttccc gcacataggc gcccaacgcc gccctgcccc
    10261 gcgagtccag ggagaactgc tcgtgcagca gcgggagttc atgctccttg acatggagga
    10321 actggctcat ccgcgaacgc atcagatcgt cgacgatccc caccgcggcc cggtagtcgc
    10381 aaccgtagaa gttctgcacc accagcagcg cgttgtgcac ctccccctcg acctcgatct
    10441 ccttctggta ggagaagaag tcgttcagca ggcaggcgta gtccgctgcg gagttctcca
    10501 ggctccgcat cacccccgtc ccgtagatct ccggcggcag ctccccctcg tgccgcagcc
    10561 ggctcagcat catggtgagg tccgaaccga aggtgcagcg ccgcatctcc aggtagtcca
    10621 ccgggtcggg aacccggtgc tgggcctggt tgtgcagctc ccacagccag ctctccagca
    10681 tcacatccat cgcacgccgc agccccgccc gcgccccggg gcccatcggc ccggccgtcc
    10741 gcgcccagag gtcggcgagc gaccgctcca tcggactcac cgcgaccgcc gcgcccgacg
    10801 ccgggtcgtc gagcggcata caggccgcca gccggtccgt gcacgccttc gcccccgcca
    10861 gatcgcggcg gcggccgaac accagcgggt agtagtcgtc cccgtacgtt ccccacgtca
    10921 gccactccgc actcagctcc agttcctcgg cagtggcgtc cggatcgatg cccgccgaac
    10981 agagcgcgaa gtcgaagccg ttgagcatgg cctcgtccca gacgtccccg aggagcccca
    11041 tccgcttcgc ccaggcgatc gaccggctcc gcgcctcctc gtggtgcggg ctgagcgaca
    11101 gcgggaacgg gcagtcgaac tcgggcagca gcgacggccc cgtcgcctgg tgcgggacat
    11161 gcgtcagcgc ccgcagccgg gccgcggccg gcctgccgaa cagcgtcctc acatccaggg
    11221 ccgacgtccc gagcactccc tcgaacatcg acggccccgc caccgccccc tcgttcatat
    11281 agcggctgga acgcagatgc cactcatggc caccggactg ccagtcctgc aggcccttgg
    11341 catacgcggc gaccgccgcg cactccgccg gatccagccc gcgctcggca cacagcgccg
    11401 ggacctccgt gagcgcggtg ttctcgaact gctgcaaccg cgacgtcagc aggtcgttga
    11461 ccgcgtccgc cgcctcctgc gtggagcagc cgaggaactt ctccagcacc agcacaccgt
    11521 tgctgttctc gccctcgtca ccgacctccc gctcgtacga gaacaggtcg ttgcgcagat
    11581 gcaccccgtc ggagaacgcg tccctcagca cccgcatcgg ccgggaaccg gcgacccgct
    11641 ccgggacctc cgcgcccgcc gcgaactcga cgagccccgc cgaccagggc gccccaccga
    11701 ccttgcggcg catctcgacg tactcgaccg gattggcgat ccggccccgg tcgatgttgc
    11761 gcagctccca cagcgactcg ttgagcagat gctccgtggc ctcggcgaaa cgggcacgcc
    11821 aggcctccga cataccgggt gccgtccgcc tccacaggtc ggcgaggccc gcctccacct
    11881 ggttggccgg ttcgggcacg ccctgtcccg ggtccggcgg catgaacgcg ggcaaccgtt
    11941 ccagataggc gctgccgccc gcgatgtcac gcgggcgctt gaagacctcc aggaagtggt
    12001 cgtcgaagaa gaacacccac acgtaccagt ccgtcaccag cgagagcgtc tccgccgaac
    12061 agtcgggatg ggtgtaggcg cacagcaggg cgtagtcgtg cgcctcgaga tcctcgggct
    12121 cccagacccc cgagccctcc agcatcccca tccggcgcgc ccactcccgc gtgtgccgcc
    12181 gagccgcgtc gacatgggga ttgaggcgcg ccggatgagg cacatagaag tccggcagtt
    12241 cgaagggctg tgccatacgt gcccggcctt tcggtgagcg tccgcgcgcg agccgcgcgg
    12301 accggtccgc gtacgggcca gccctacccg tcgccgctcc gggccacgcg accccggtga
    12361 tcacccgtcc gggtgaaccg ggggcgcacc gccaccccgc ccgctaccgc ctggtgacca
    12421 gcacgtcggc ggctttcacg aacgccaccc gatgaccgaa ctggatcacg tggtaccgct
    12481 cttcgccgcg caccaccgtg tgctgcgacg cgtcgaaccc cgtcgcccgg tagtactcgc
    12541 ccggcatgct gccggcggtc acatacctct gccccgcgag cagcttgtac ggcagcggcg
    12601 tcaccgcctg caccggcaca cccggcgggt acgccgacgc ctccggatag gcgcgcccgt
    12661 acaccggaac ctccgccagc cccgcccgcg gggtgacgag cacggcatgc gcgcccaccg
    12721 cgaccggccg ggtacgcggg ttgtggaacc acgccttccc gcccaggtac cacacggccg
    12781 tccagtcccc ccggcgctcc gcgacggcgt accgctgacc cgtggaggcc cgcgcacccg
    12841 tgtcgttgac gcccgtggtc gagtcgccgc cgtccgggcg cagcccggcg tccttcacca
    12901 gcggcgacga cgcgtccggg gcggtgtgca gccggaccgc acccgaaccg tgcggcgcac
    12961 agccgccgcc cgcctcggca cagcccgtgt acaccggccg gtgccggtcg tagtcgggac
    13021 ggatcgtcac cgctgcggcg cccggccccg cggtggccgc gaacggccgc cccaggagcg
    13081 tgaagtagtg cgcccagtcc cagtacggac ccgggtcggt gtgcataccc gggacggtcg
    13141 acggcagggt gcccgggacg ttgtcgtggc cgatgatgtg ctgccggtcc agcgggactc
    13201 cgtaccgccc ggcgagatgg cgcaccagcc gggcggaact gcggtacatc gcctccgtgt
    13261 accaggcgtc ggggctgacc aggaagccct cgtgctccag cccgatcgac ttggcgttga
    13321 tgaaccagtt gccggcgtgc cagccgacgt ccttgagcct cagatgctgg gcgacatgcc
    13381 cgtcagagga ccgcagcgag tagtgccagg acacgtactc cgggtcctgg accagccgga
    13441 gggtggtgtc ccaggtcgcc tcggtgtcgt ggatgacgat gtactcgacc gactgcgaca
    13501 cgggcctgtc cgccttgtcg tggttgccgt agtcgccctc accgaactgc tcgtacgggg
    13561 cggggatcca ctcgcaggcc acggtcaccg gacactcggt gagcgtccgg tccgcggtgc
    13621 gcagacccag ccgggccacg gcagacctgt cgggaggcgg acccccgtcg gcccgcagcg
    13681 acacccgctg gccgccgtcg gtggtccggc tctgcccggt gcggatgacg tcgaacacgt
    13741 cgtcggcgta tgccgtcgcg gtcgccgtgt cgtcggcgcc cgagaaccgg gcgaccgccc
    13801 cgaaccagtc cgccgcaccg ccgcccggcg ccccgcccag ctcccgctgg gcgtccgcga
    13861 gcagcgccgc gcctccccgg acgttcgccg acgggtcggt gcgcaggcgc tcggcgggga
    13921 taccggtgag gtccgcggcg cgctcgaggg tccgcaaccg ggccggaaac acggcacgct
    13981 ccccgagcgc gtgtgcgcca cccgtccggg gcacccgcgc cgtgtcgccg cggggatcct
    14041 cagcgccgtg cgaatggtgc ggagcctcgg ccagggccgt cgccgcgtcc gtcagatgca
    14101 tgggcccgta gccgccggtg acactggggg cgccgccgtg cccgtcccag cgcgactgga
    14161 tgtaggagac gccgagcagc acattctgcg gcacccggta ctccgcggcg gcgtccgcga
    14221 aggcgcgctg gagtccgcct gacggcgctg actgctccgc ggtggcggac ggggcgccgg
    14281 aggccagggt cagcagcagc gccgcgacca ccgccccccg cctgcgaaca tgtctcggtc
    14341 gtacggggac ggacgcctgc aacgcagcct ccagtgacgg acggtgcccg ggggatccgt
    14401 acaggggtag ccgttcccgg acgatccgtc aatgaggctc ggcggtaggg aagtccacgt
    14461 cggaccgggc cgaagacccg gaccggcggt cggcggaggc cggtggagga aaccggcgac
    14521 caccggcggc ggagcatcgt gacacggcct ccggtgccgg cagtccgtcc cgcccgcccc
    14581 gcccacgacc gcgggccact ccggacacgg caccgcgccg ggctgccggg ctgccgcacc
    14641 gaccgatccg accgcaccga ccgatccgac cggccaccgg actcagaccg gcggcacgac
    14701 cgccacgggg cagggcgcgt ggtgcagcgc ggcatgggcg acggatccga tccgcgaacc
    14761 gactggggag cggcgcgccc gccggccgac caccagcagc cgcgcacggg cggtggcgga
    14821 cagcagcacc tgcccggcgc tgccgatctc gacatgctcc gtcaccggca ccccgggata
    14881 gcggtcccgc cagggcttca gcgcctccga cagcgccttg cgctcgaacg gctcaaggcc
    14941 gccggcctcg tccgcgagcc tcatcgcggc cgggctgtag gtgtagagcg tcggcaggct
    15001 ccacgctcgc accgcccgca cccccactcc gtgtgcggcg gcggtctcga aggcgaagcc
    15061 gaggaccgcc tcgcagtcct ccggcgcgcc ctgctgcccc accacgatct cgtcgccccc
    15121 gccgggctcg gggtccgcgg cccgatcctc cccggcgggt gcgcgaacgg cgacgacggg
    15181 gcaggacgcg gaggcgatca cctgctggcc gtaggagccg acgaggaaac cgacgacggc
    15241 gccgtgccca cgcgagccca gcaccagcat cgtcgcgcgc tcggcctccc cgacgagcgc
    15301 cgccaccgcg gtgtccggaa ccacctcggc ggacaccggc acatccggga aacgccggct
    15361 gatctccgac tccgcctcac gcagcagact ctcggcggcc cgggcctgcg cctcccggtc
    15421 ctgcacgatc ggaacgtcga gcggctgcca cagccatgcg tgcaccagac gaagaggaag
    15481 cccgcggagc gccgcctcgc gggccgccca gtacgccgct gcccggctct ccggcgatcc
    15541 gtccactcct gcggtgatgc atcgggccat cgggttgtgc ctccgtccgg ggccagggct
    15601 cgaccacgcg ggccgccctg tgcgaatcgg tccagccgaa cccgacccta caggggcgaa
    15661 ccggcaggcc ccggacccgg cctccgatac cgccggaacc ggccgcggcc cgccccgggt
    15721 tccccggtgc cggacacccc gcaccgccgg ccgcggcccg cccccgtccg gtgggccgcc
    15781 ggtcgaccga gcggtgacgg gtgctccccg ctcagccccg gaggggcacg ggagccgggt
    15841 gcgagcccgg ggtggatccg cccaggggga agaagcgcag gagagggcac gcaggagaag
    15901 cgggagaggg cacgcaggag aagacgcgta ggagaagacg cgcagggaag cgttgaggga
    15961 agccgccgga catccggggc gtacggcccg gcagacgaca gagcgctgtg tgtccggtgt
    16021 gtcggcactg gacgcacagc gctcttcccc ctcgtcgcgg tcagcgcgtg ccgaccgccg
    16081 cgcgcacggc ccgccgtgcc agcgcgcagt catcgtgcag ccgccgcagg agcagccgct
    16141 gctcctctcc ggaggagagt ccggtgtgcg gcggcgggac ggtgccggcc ggcggcgcct
    16201 cccgcatcgt ccgctgcacc gccgtctcgt aggttctgat ctcccgggtc agcaccagca
    16261 tcaggttcac caggaaggcg tcgcgcgccg ccgggccgga ctgctgggcc agctggctga
    16321 cctgccgccg cgccaccggg gcgtcgccca gcaccgtcca cagcgtcgcc aggtcgtaac
    16381 ccggcagata ccagcccgcg tgctcccagt cgacgagtac cgggcccgtc ggcgcgagga
    16441 ggatgttcga cagcagcgcg tcgccgtggc agaactggcc cagcccgccc tgccgcccac
    16501 cgtggtgcgc gagcccgtgc agcagcttct gcagatcacc cagatcgcgg tcggtgaaca
    16561 gaccgagttc gtggtagcgg gcgaaccgcg acacgtagtc cagcggcgcg tcgaacatcc
    16621 cggaaggcgg ccgccaggag ttcaaccgcg cgacggcccc gagtgcggca cggacgtcgg
    16681 cgcgcggcgg tgcctcggag gggtgccggg cgagggcggc ggggcggccg ggcatccgct
    16741 cgacgaccag cgtgcagttc tccgggtccg cggcgatgag ccggggcaca cgcaccggtg
    16801 gccggtgccg gacgaacgca cggtatgccg ctatctcgtg ccggaaccgc tccgcccacg
    16861 cgggcgactg gtcgagtaag cacttggcga cggcggtggt ccgccccgtc gtgccgacga
    16921 gcagcaccga gcgaccgctc ctgcgcagca cctgtaccgg attgaactcc gggcagatgc
    16981 ggtgcaccga ggcgatcgcc atgcgcagct gcgcgccctg cgggccggac aggtcgattc
    17041 tcccgctgag cggctggccg accgcccccg gccaccgccg ggccctgccg gccgcggagg
    17101 gctcgagcag cggcccgccg cccgcctgga gggtgcgcgg ccggggcggg gcggacacgg
    17161 aggacgatgc tgtgtacatg ggcgatacag atcccttcgt gtgccgacaa ctcgcgtgcg
    17221 cggccctgcc ccggaagcct tcggcaccct ggggaatgcg tctcgctccc ggggcggggt
    17281 ggcgctttcc tacctgacac ccgcccgcgg gtggcacacc atctggcgga ccctggcgaa
    17341 gcctggcgaa tagtcgcggc gcatctgaca gggggttact gtcaactcag ccgagaacct
    17401 gggggcttga cgtgaccgga gtacccaaca cccgtctcgc ggacctgttc ggcctcgccg
    17461 gctggtccaa gggcgaactc gcgcggctcg tgaaccggca ggcggcggcc atgggccatg
    17521 cgcagctggc gaccgacacc tcgcgggtgc ggcgttggat cgacatgggg gagtccccgc
    17581 gcgatcccgt gccgaaggtg ctggcggctc tgttcaccga gcgactcggc cgtgtcgtga
    17641 ccatcgagga cctcgggttc gtacggcacg ggcgcacgcg caagcggagg gaggccggcg
    17701 gcgtcggcca ccccgacgga ctgccctggg cacccgaacg tacggcggcg gtcctcaccg
    17761 aattcacggg aatggacctc atgctcaacc gacgcggctt ggtgggcgcg ggcgccgcgc
    17821 tcgccgcagg ctccgcactc agcagcgcca tgtacgactg gctgcacacc gaccccgctc
    17881 tcgccaccca cgccccccgt gtccacgacc ccctgcacgc cgaccccgcc gggttcgacc
    17941 gctacgaggc cgcgcccatc gggtcgcagg agatcgacgc cctcgagcgc tccgtcgagg
    18001 tgttccgcgc ctgggacgcc tcccgcggtg gcgggctcca gcgcaaggcc gtggtgggcc
    18061 agctcaacga ggtgggcggc atgctcgcct accggcaccc cgaccacctc cagcgccgcc
    18121 tgtggggtgt cgccgccaac ctcgccgtac tcgccggctg gatgtcccac gacgtcggcc
    18181 tcgaacccac cgcccagaag tacttcgtga tcgccgccca cgcggcacgc gagggcggcg
    18241 accggccccg cgccggggag gccctctcca gggccgcccg ccagatggtg catctgggcc
    18301 ggcctgacga cgccctcgat ctgatgaagc tcgccaggtc cggctccggc gagtcgacac
    18361 tgccccgcac gcgagcgatg ctgcacacca tcgaggcctg ggcgcaggcc tccatgggac
    18421 gggctcaggc catgcgacgg accctgggcg aggcggagga gctgttcgtc tcggacaagg
    18481 gcgatgtgcc gccgccgagt tggatgcaga tgttcgacga ggcggacatg cacggcatgc
    18541 aggcgctcgc ctaccgcacc ctcgcagagc acgatccggc cgccgccggc atcgcccagc
    18601 gccatgccaa gcaggcgctg gaactcaggg agggcggtcg ccagcggtcg aagatcttcg
    18661 actacatctc catggcgtcg gcgtgcttca tcgccgacga cccggaacag gcggacaggt
    18721 atgcccggct ggcgctggtg tcgatgggag agacctcctc gcaccgtacc tgggaccggc
    18781 tgcgggagat gtaccgcctc acgggccagt tcgccggcta tgcgaagatc gaggacctgc
    18841 gggaggaaat ccagcacgcg ctgcccaaca gcccgtcccg gagcgagcgg agcgtcagga
    18901 tctgaagccg agcccgggaa acccggttgc tgcctgctgc ctggtgtctg atgccggctg
    18961 agggctgccg gctgagggct gccggctggc gatcgacagc tgacagccac cagttgacag
    19021 ctgacggata gcagctgaca gatattgaaa agtgtcactc cgtgagcgtt ttcatgattc
    19081 cggtatggcc ggccgacgcg ggccgcgctg gagggacgat gccaccgagg gaaccggaga
    19141 agccgaagga accgcagcaa gcgaagcgac gaggacaccc gcaacgtcag cacgccgacg
    19201 gcgaacccgc ccgccgcgca gccgctccgt gcctcttgtc tgtcaggcga tcgtctgtca
    19261 ggcgatcctg gccaccatca ccgaggcgtc gtgctgacgg tcgcccacgt cgaactcctc
    19321 gacgatcagg cgcacgcagt cctgcgcgct ccgggcgacg gtgagtcggg gggcgagggc
    19381 gagcagccgg tcgtgtccgg tgctgtcatg gggggctccc gtccctctcg tcagtccgtc
    19441 cgtgtggaga accagcacat cgccgggcag cagggcagtc tcgccctgct cgtacacacc
    19501 tccggccgtc gcgccgagca ggacgccgcc cggtcggggc agggcacgcc ccaccccgcc
    19561 gcggtacagc agcggggcag ggtgccccgc ctgcgcccac gagaggatcc gggtcgacgg
    19621 gtcgtagtgg cagcacacgg tgctgccgag tgcgggctgc gcagcggagt ccagcagcgc
    19681 gttgaggtgg cccatcagcg ggccgggccg gatgccggcc acggcgagcg cccgctgggc
    19741 tcccatcagc atcgccatgg cggatgtcgc ggtgaccccc tgaccggtca gatcgcccac
    19801 gctcagcagc gccagtcctc cggggatttc ctgggcgtcg aaccactggc tgccgttgag
    19861 cgccccgcgt ggagacggga ggtggtggcc tgcgaggtcc agtgccgccg gaccgttcgc
    19921 ggggatgctg cgctcgccgc gccagggcgg gaggaccgct tcgtgcatct gtgtcgccac
    19981 acggcgctcg gtgcggtcga tgtgctgtcg tcgggtgagc gtgtcctggg attcgcgtac
    20041 cgcgcgctgg gatctgcgca gttcgctgac gtcgcggagg accgcccaca tcgaggcggt
    20101 gcagccgtcg gcgtcgagga ccggttcgcc cgtcatgtgg agtgtgcgga cgcgcccgtc
    20161 ggcgcggacg atgcggaact cgccgtcgat cggttttccg tctaccaggc agtccgtcac
    20221 catctcggtg agtaacgcct ggtcctctgc gaacaccatg gagggcagct cgtccagggt
    20281 catcgggtcg ccggcggcgg ggcgtccgaa gatccggtgc agttcctcgg accagctgac
    20341 ctcgtccgtc agcaggttcc actcggcgct gccgacacgg ctgagcagtg aatccggtcg
    20401 cggtggcagg tcctcgaacc cggcctggtc ctcccggccg ggtgggccgt cgggccccgg
    20461 caggggaggg agtccctccc tgagctggcc caggtgcgcg ccgaggtcgt cgagctggtg
    20521 gaccgccagg tcgcacaggg cccgctgcca gcggccctga gggtcgtcct cgtccaccac
    20581 ggcgtcccgc cggaccgcgt cgacgtctcc gcgcagtcgc cgggtctgcg agatcagctc
    20641 gtccaccgag tcgcgccgtg gaggctgcgg ggcgggacgg tccgcgaaca gatgggacgg
    20701 catgtcgtac tccgatgcag gcgcggcatg gccaggtctc agcgaaagac cggttatgac
    20761 tgttgcacag gtaccggggg tgtgtaaggg atttggcaac actcgatacg gtggtgcacc
    20821 tggcatatgt caatggcccg cagtgcgccc gaccagccat gacgtcgttc cctgttactc
    20881 ctgagtcctc gtgaggcgtg actccgtgat gtcctgttcg aagccctcgg tggcagcggt
    20941 catcggcgaa ccgggctgag gggtgggtcc cgtacgcggc gccacgccgg taccggcacc
    21001 ggcaccggcg caacgcaggg gccggtaccg ggaccggcac cgggggcgaa gcgtgaccgc
    21061 gcggtgtgac cgggcgccag gcaccgggca ccagacatcg ggcaccaggc acggggccac
    21121 gggcgccgct tcggtgggcg ccggtgccgg gccgtctcgg tctgtcccgg gccgggtggc
    21181 gcatctggcg gaagcgcgcc cgacgtcgat cacgatccgc tcgggcgggt ggaggcgcct
    21241 ggtcctgcgg accggcgtgg agcccgaggc cgccccgaac ccgacgcgac catcgaagtg
    21301 gacggcggtg cgggccggcg gccccgaccg ccggcccgca ccgcaggtca ggcgccgctc
    21361 gcgcggagca tcccctcacg gtcgacgatc ttcacccgct cgcggccctc gggctcgccc
    21421 agcgcccgct cggccgcgtc cagccggtac cagccgtccc acgtggtgta gcggacggtc
    21481 cgctcctcga ggaaggcgac gaccgcctcg gggtccggcg ccgacggtgt gtgcaggcgg
    21541 ccgttggcgt ggtcgtcgag gaggctcgcg acggtctcgt tggcgtctcc cttggtgtgg
    21601 ccgatgaggc cgacggggcc gcgcttgatc cagccggtga cgtatgtcga ctgcatacac
    21661 cgcccggcct cgacgacacg gcccgcctcg tgcggcaccg tgccgctgcc gaggtcgaag
    21721 ggcagtttgg cgatctcctc ggagaggtag ccgaccgcgc ggtacaccgc ctgcacgtcc
    21781 cagtcgcgga actcgcccgt cccggtgacg ttcccgctgc cgtcgagggc cgtccgctcg
    21841 gtacgcagcc ccgtcacccg gccgtcctcg cccaccacct cgacggggga ctcgaagaag
    21901 tggaggaaca gcttgtgcgg ccggttcccc gcatcgcgga tcgcccagtt ctccagcgtc
    21961 ttggcgacca tgtccgcctg cttgctggcg cggcgcgtgg cgatggaccc cccgtcgtag
    22021 tcgatgtcct cgggattgac gatgacctcg atgctggggg agtggtccag ctcgcgcagt
    22081 tccatcgggc tgaacttcgc ctgcgcgggg ccgcggcgcc cgaacacatg cacctcgcgg
    22141 gccttgttcg cggccaggcc ctcgtacacg ttcggcggga tctccgtcgg cagcagctcg
    22201 tcggcggtct tggcgagaat gcgcgccacg tcgagtgcca cgttgccgac gccgag
//
