LOCUS       NZ_CP029254            12922 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Streptomyces spongiicola strain HNM0071 chromosome, complete genome.
ACCESSION   NZ_CP029254
VERSION     NZ_CP029254.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces spongiicola
  ORGANISM  Streptomyces spongiicola
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7180417)
  AUTHORS   Zhou,S. and Huang,X.
  TITLE     Complete genome sequence of the Type Strain of Streptomyces
            spongiicola HNM0071, the producer of staurosporine
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7180417)
  AUTHORS   Zhou,S. and Huang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2018) Institute of Tropical Agriculture and
            Forestry, Hainan University, No 58, Haikou, Hainan 570228, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: ABySS v. 2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 850.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003122365.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 01:04:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,008
            CDSs (total)                      :: 5,921
            Genes (coding)                    :: 5,739
            CDSs (with protein)               :: 5,739
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 182
            CDSs (without protein)            :: 182
            Pseudo Genes (ambiguous residues) :: 0 of 182
            Pseudo Genes (frameshifted)       :: 47 of 182
            Pseudo Genes (incomplete)         :: 161 of 182
            Pseudo Genes (internal stop)      :: 9 of 182
            Pseudo Genes (multiple problems)  :: 32 of 182
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:10:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3393158
            Orig. end                         :: 3406080
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029254.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..12922
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="12"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..12922
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12922
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7922](-)"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7922)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     gene            complement(307..1197)
                     /locus_tag="DDQ41_RS14885"
                     /old_locus_tag="DDQ41_14885"
     CDS             complement(307..1197)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04267.2"
                     /locus_tag="DDQ41_RS14885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_14885"
                     /product="aKG-HExxH-type peptide beta-hydroxylase"
                     /protein_id="WP_109294931.1"
                     /transl_table=11
                     /translation="MSALSPEALVTVGGIADHQRLRTSRIASVLGNRLGSSALDYAVAH
                     HLLEGAEHAARTRDADRLTWYRNWTVRDLTHLSVDPHLVLSPRPADLLCSEISETAYYL
                     VGPDTAPATPEAQVIMRAALASATEHGFSRLLTQHAPVICLLKRRRLDETLHSWALTRL
                     PGTVFTDYTAYPEVMARDLIHEAAHNWLNDALAANNVRLPADVTFFSPWRGTRRSVFGF
                     LHACWAFSLTVLYVREARRSATDAVVPFLDTHLRQQAVQFAAATECLEQALSYVPANEI
                     RERIGRAVGKVVGPA"
     gene            complement(1254..1415)
                     /locus_tag="DDQ41_RS31305"
     CDS             complement(1254..1415)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DDQ41_RS31305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162602684.1"
                     /transl_table=11
                     /translation="MAEDKTFDEFLEAVASLRDSDPVRTTAHTSNAATETWLATTVQPN
                     AAEPTTET"
     gene            complement(1505..2224)
                     /locus_tag="DDQ41_RS14890"
                     /old_locus_tag="DDQ41_14890"
     CDS             complement(1505..2224)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311996.1"
                     /locus_tag="DDQ41_RS14890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_14890"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_109294932.1"
                     /sec_met_domain="PhyH (E-value: 0.00014, bitscore: 20.6,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHIAETLSIRTVESFLKPNEIDRLNDVMDGALGSFGRDRYGAGR
                     HTTIHEIPGRSPSEAQDVYEPAGRIEMTDIPYEATTLLDQALKLHMAAVTRTLPSVTGH
                     RPWIYLEYGAGQYITPHADGIAPDPLTRPRQIAAATVTLTDLQDTGGAFYVETTGSDAV
                     WTADEAPTESGYAHGMRFAHDGTDMSSPWFRTMPRTRWSVTPAPGTLVVFGSQLIHGTE
                     PVRAGRVRKFLTLFVSE"
     gene            complement(2221..4107)
                     /locus_tag="DDQ41_RS14895"
                     /old_locus_tag="DDQ41_14895"
     CDS             complement(2221..4107)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311997.1"
                     /locus_tag="DDQ41_RS14895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_14895"
                     /product="radical SAM protein"
                     /protein_id="WP_109294933.1"
                     /sec_met_domain="PTHR43273 (E-value: 4.3e-40, bitscore:
                     136.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVTRTAPTDLESLYAPLSNTGPDTAVSVILKLRGETCDIDCLYC
                     FEKRKEAPGGARINAAQVHRLGSIFSGRPLSIELHGGEPLTAGRERIAEILDALAAQPN
                     VLRVSLQTNGLRLDDAWLDLFEQHCPELEIGISLDGDALGNSWRVGYDGRPTYPRVVEA
                     LELLGRRERNVGVICAVTPYVLGRASEVMEHLASFPAVTTVSLVPCFDAAVTRSTMVVG
                     SRAPTSRALQRRAIGPTGPAWAVTPRQYADFVLEAAHHWVADGLFRRVKLEPVVSVIRR
                     LKGLQTRSCHFSDLKCDHVLTLYPDDRLGSCDELPWPQASLAALGDIHAEADIAGAQGG
                     SPLLQQARSLVTKCTTCDYRDSCGTGCPAVRLRFAAAGDEDAYCDHRMRLIDGVAALLA
                     QPSFPPGASCSRLRWRPVRPNDMQHVAAFMARWDDPTVPRKPARLQVSAQGNINTVGLP
                     GVHEADDLDPHHPQWYEGIEPGIRPVVDALTAGWNAITYDSCQGHAYADLPGAEPRFLS
                     VGILPRDRDEYARTAARLCRAADRAEPSLPGTCSLVLGRSELTCRTTGRAYPTLDLHLV
                     PAAGIAPAEYFEDLAQAVHVLTEALAEAASAPPSTRCACATEAARSSDGGEQ"
     gene            complement(4138..5004)
                     /locus_tag="DDQ41_RS14900"
                     /old_locus_tag="DDQ41_14900"
     CDS             complement(4138..5004)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DDQ41_RS14900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DDQ41_14900"
                     /product="hypothetical protein"
                     /protein_id="WP_109294934.1"
                     /transl_table=11
                     /translation="MNPSARLRREIADRVAQSLLASGEAREVWLEGALACGFAHAASDI
                     DLRGIVDGTLPVWESRIVDGVRVDLQATAPQRAEELRHLFRSFDVRRDDLSSFRRVRAS
                     MHDLMCLRTALSYGSGRWNPVLAPEERQGYRRWAVADQAEVAASLAEDLTGLVEDGLAE
                     SVGVVCRKLETCLAALDCAAAGHPVLGDKWLPLLTGAPPRPSINPARAETWEWFRPVQR
                     RVARALLGCWPVDDPLQKPPSLGAPDAGWLPQRYADGWFLRRGDVHIPITGGQLLGWLS
                     AVSTDGA"
     gene            complement(5001..5924)
                     /locus_tag="DDQ41_RS14905"
                     /old_locus_tag="DDQ41_14905"
     CDS             complement(5001..5924)
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072: dehydrogenase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014841.5"
                     /locus_tag="DDQ41_RS14905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_14905"
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="WP_109294935.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2.3e-18, bitscore:
                     64.6, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVLVVRGAADAGAIRRALPGVLVHDFLDLKWPLPADTAVVVLR
                     SGVRLGERELDALPRLRHVVRTGSGIDHIDVSALQRRGITLHRNAEAGAGAVGEWVLAA
                     ALALARRIPLGQHALLLGQHEKHACMGAPLGTLTAGIWGAGPVGLAAEWALAPYVDRTA
                     FAAWPSNSPGLRELSPTALMEQSQVHVIALPLRPTTEQLIGEDFLARVTPQRPLLICAG
                     RLETLDVAACLRALADGRLSGLALDPVEREHLPLLTGSTTPLNLLASPHIGAQRSDVRG
                     ALDRWAIDLLKEITAADKILIEGGHR"
     gene            complement(5921..6586)
                     /locus_tag="DDQ41_RS14910"
                     /old_locus_tag="DDQ41_14910"
     CDS             complement(5921..6586)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311988.1"
                     /locus_tag="DDQ41_RS14910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_14910"
                     /product="TylF/MycF/NovP-related O-methyltransferase"
                     /protein_id="WP_109297742.1"
                     /transl_table=11
                     /translation="MDPKLNDLREWLLREHSGTVCADRLRVIADELAALTARGLPGPVV
                     ELGCYRGAMALWIRSVLDSLGDRDREIHVYDSFQGMPAPGDEDSDHLAAGELRSSPDDV
                     RATHTAWDRPTPVIHPGWFDETLPKELPSEIAFAYLDGDFYDSTLTGFTHCVPRLVPTG
                     VLLVDDYADTAVNPRAWDGLPGVKRACDAYFGAPSPVTVVVGEGDLAFGRYEKPGTLG"
     misc_feature    complement(6194..6196)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6592..7062)
                     /locus_tag="DDQ41_RS14915"
                     /old_locus_tag="DDQ41_14915"
     CDS             complement(6592..7062)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311905.1"
                     /locus_tag="DDQ41_RS14915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_14915"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_109294936.1"
                     /transl_table=11
                     /translation="MPLTPELPRISVSVKAAIVRDGAVLLLSYDDETGFHYNLPGGKAQ
                     VGEDLRQAVNRKVAQETGLQVVARHLLCVVEYVPESWQGEFGDVQKVQFNFLAEQVDDA
                     EPRMPEPPDPIQVGFEWIPLERLGDVYLLPRINRPLSAALNGELADPFVDRW"
     gene            complement(7053..7922)
                     /locus_tag="DDQ41_RS14920"
                     /old_locus_tag="DDQ41_14920"
     CDS             complement(7053..7922)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311939.1"
                     /locus_tag="DDQ41_RS14920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_14920"
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_217364436.1"
                     /sec_met_domain="phosphonates (E-value: 4.4e-67, bitscore:
                     224.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.8e-49, bitscore:
                     166.9, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADDPKGTRLRETLDDSERKHPLLAIGAVNALAAHVAAEAGFDAL
                     WVSGLEVSAASGLPDANVLGPRDLSDVVASLGRVTELPVIVDIDNAGGSGRTAERFAYD
                     LMRAGAAAVCVEDSAYPKCNSFAAHRAQSLADRDLLCEQVGRIRKLAGDDLVVVARTEA
                     LIAGEGMATAIARAEAYAEAGADAILIHSKDAAGDQARAIGRAWNHGVPLVSVPTAFPD
                     VSAAELGEAGFSLCIYANQLSRAALAGMRTAARQFRRGGSFRSTVAGSLAEVGDLMRVG
                     EPEALSCL"
     gene            complement(7915..8601)
                     /locus_tag="DDQ41_RS14925"
                     /old_locus_tag="DDQ41_14925"
     CDS             complement(7915..8601)
                     /EC_number="2.7.4.9"
                     /GO_function="GO:0004798 - thymidylate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0006235 - dTTP biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311999.1"
                     /locus_tag="DDQ41_RS14925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_14925"
                     /product="dTMP kinase"
                     /protein_id="WP_109294937.1"
                     /transl_table=11
                     /translation="MNHRYPFIVIEGLDGTGKTTLRKGLFRLWEGLYGVTPLCVLTTNF
                     LAPDQAAAIVTGKYQPNAGIRDAYLSAIVADKRATLDRLVLPQRAARPVIADRWLLSEL
                     AFFAVKHGMRASETYGALAAQLTVAPDITLVLDLETDASMSRAQARQGDAVRADWDVRD
                     VQSRVRETYEAVVSKPDEFPLLGDVVRLDARRPRSEMLLAAWDVLRERQLVPSLAAPAE
                     GGKIHG"
     gene            complement(8598..9359)
                     /locus_tag="DDQ41_RS32020"
     CDS             complement(8598..9359)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DDQ41_RS32020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_217364437.1"
                     /transl_table=11
                     /translation="MTSLTLPPRPPDSPPLIHAWQTLADGLLTQRLHLHLDEWRAAVAE
                     EKALPDVPSADVSVLAQRPSPLPAGDESAMALLEDAGLGFWWELPQRHGAESRNRRGAL
                     HRAADTAAQNLLAEQSGAAWCGAVTAVSAAAAWWVGFFAVIRHRGVHHITLEPHPGTLH
                     EQALGTAVGTVAYGMATRVIEAALRGSVDDPTLRAAYCRAIEAGICAEPELPRLIDELA
                     ELRLVDLVSTTARWRGRFTKYAGGTGAGQVE"
     gene            9668..11080
                     /locus_tag="DDQ41_RS14935"
                     /old_locus_tag="DDQ41_14935"
     CDS             9668..11080
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.5"
                     /locus_tag="DDQ41_RS14935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_14935"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_162602685.1"
                     /transl_table=11
                     /translation="MAAWELGTVVKLFRQHTGLSQAGVARMVNIDQAEVSRLERGLKQI
                     RDRRQFVQWTDALGVPEELLGLLPTADPHIPDSKGRPGAADVGARGYAALPEGPGQLLL
                     PAGRSVSTTALPVLTLPAASFLGDSLRLDSRPELDAWRTMPMRALIVANRTVDGAVRQF
                     VTDARPSGVRATASDPVYIPAAYELDDLTYGILWAMSGFEAALLGDDQTLHTSLASFTA
                     SPGLPLASDLGLTEVSRMLIGSETAARYILGHRDHLGDAPVFWTREQHGEEAATWLFFR
                     HKYQYLERMAPKRPGGTSGRGFCVPEAAVASSPAYERVLLFLAIALMESSGIRTWVTDD
                     GGFAHTDGFALSHGRRAVIATWVRAEGASHLAVTARPGALRTFADVTSHVSQHSATAAE
                     QAGQRLAATAEYLGLDASWLGRRCAQLSAVGTERLARPRSRLLGLEGLEAACRFVAEQL
                     VIIPRTRTAPTR"
     misc_feature    9977..9979
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11140..12141
                     /locus_tag="DDQ41_RS14940"
                     /old_locus_tag="DDQ41_14940"
     CDS             11140..12141
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311949.1"
                     /locus_tag="DDQ41_RS14940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_14940"
                     /product="asparaginase"
                     /protein_id="WP_109294939.1"
                     /transl_table=11
                     /translation="MTESVRNVAVFSLGGTIAMTTDPTTGGVVPALSAHELLAAVPALA
                     TSGIGLKVRDFRRLPGASLTFEDLTALSAAIAAELETGDVDGVVITQGTDTIEETAFLL
                     DLYHGHEQPVVVTGAMRNPTLPGADGPANLYAAVLAAADPGLSGADCLVVLGDEVHSAR
                     AVRKSHTTSPGAFASPACGPIARIAENRVRMVGGLPRRGPLVGAPDREARVGLYTVTLG
                     DDGALLDVWDGNCDGLVVAAFGVGHVPERLVEGLTKLASRIPVVLASRIGNGPVLSDTY
                     GFPGSEKDLLGRGLISAGDLGPYQARLLLHALLAQGADGATVRETFTTASTR"
     gene            12169..12627
                     /locus_tag="DDQ41_RS14945"
                     /old_locus_tag="DDQ41_14945"
     CDS             12169..12627
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311896.1"
                     /locus_tag="DDQ41_RS14945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_14945"
                     /product="PPC domain-containing DNA-binding protein"
                     /protein_id="WP_009311896.1"
                     /transl_table=11
                     /translation="MRAHELTVGRTFGVTFDHGEDFFEALSTFCRDNGVRQGYIPSFIG
                     AFAEAEIVGACEKLADPDAPVWAKTYVTNVEAFGAGTLAHDPATGGILPHIHVSAGLKA
                     QSADGRTSHLLSAKVQFLSELLIVEVTSPTMTRPRNPDLYDVPLLTFG"
ORIGIN
        1 cgccctcggg ccattcggcg tcgtcccgta cgtcacgggc gaggtcaccg atggccgact
       61 gttcgccgac gtggcgcatg agccaggctc gaaaattgct cggctcgttg gacatgcgta
      121 ccccctgggg cttcgtgatg ccagcccttt gacggcatcc cttgctcaac gcctatcacg
      181 caccgttgtg ttcggagcag taaactgaaa taccgactga aatcttccgt gcgtgactga
      241 agtcttccgc gcaatccaaa atgtgtagtg gcgaaccgca ggtcccccat cgaacttggg
      301 cggatgctac gcgggaccca cgaccttgcc gactgcgcgg ccgatgcgtt cacggatttc
      361 gtttgcgggc acgtaggaga gggcctgctc caagcattcg gtagcggcag cgaactggac
      421 cgcctgctgg cgcaggtggg tgtcgaggaa gggtacgacg gcgtccgtgg cgctgcgccg
      481 cgcctcccgt acgtacagca cggtgaggga gaaggcccag cacgcgtgga gaaagccgaa
      541 gacggaacgc cgcgtgcctc gccaggggga gaagaaggtg acgtcggcgg ggaggcgaac
      601 attgttagcg gccagggcgt cgttgagcca gttgtgggcg gcctcgtgga tcaggtctcg
      661 ggccatgacc tcggggtacg cggtgtaatc ggtgaagacc gtgcctggga ggcgggtgag
      721 ggcccagctg tggagggtct cgtcgagccg gcggcgcttg agcaagcaga tgacgggggc
      781 gtgctgggtg agcagcctgc tgaagccgtg ctcggtggcg gaggcgaggg cggcacgcat
      841 gatcacctgg gcctcgggcg tggcaggggc ggtgtccggg ccgacgaggt agtacgcggt
      901 ttcggagatc tccgagcaca gcagatccgc ggggcgtggg ctgagcacga ggtgcgggtc
      961 gaccgacagg tgggtcaggt ctcgcaccgt ccaattccgg taccaggtaa ggcggtccgc
     1021 gtcccgggtg cgtgcggcat gttcggcgcc ttcgaggagg tggtgggcga cggcgtagtc
     1081 gagggcggac gagccgaggc ggttgccgag tacggaggcg atacggctgg tccggaggcg
     1141 ctggtggtcg gcgattccgc cgacggtgac cagggcttcc ggggagagag cgctcatctg
     1201 ggactccggg gtggaacggg gccggaccgg gacgggcccg gccccgtggc gggtcaggtc
     1261 tcggtggtgg gctcagcggc gttgggctgc accgtggtgg ccagccaggt ctcggtggcc
     1321 gcgttggagg tgtgcgcggt ggtgcgcaca gggtcgctgt cgcgcaggga cgcgactgcc
     1381 tccaggaact cgtcgaacgt cttgtcttct gccactgctc gctctctcgt ctggtcgggg
     1441 ccgtgggttg ggggcgggtg gccgtgaggc gggccgcggg gtccggtcat gatggcgaag
     1501 cttcctactc ggagacgaag agcgtgagga acttgcggac gcggccggca cggacaggtt
     1561 ctgtgccgtg aatgagctgg ctgccgaaga ccacgagcgt gccgggtgca ggtgtgacgc
     1621 tccatcgggt gcggggcatg gtgcggaacc agggggagga catgtccgtc ccgtcgtgtg
     1681 cgaagcgcat cccgtgggcg taacccgact cagtcggtgc ctcgtctgcg gtccagacgg
     1741 cgtcgctgcc cgtggtctcc acatagaacg ccccgccggt gtcctggagg tcggtgagcg
     1801 tgaccgtcgc ggccgcgatc tgccggggac gggtcagggg atcgggggcg atgccgtccg
     1861 catgcggggt gatgtactgg ccggcgccgt attcgaggta gatccatggc cggtggccgg
     1921 tgaccgaagg cagggtgcgc gtgacggcgg ccatgtggag cttgagggct tggtcgagga
     1981 gggtggtcgc ctcgtacggg atgtcggtca tctcgatccg gccggccggc tcgtagacgt
     2041 cctgcgcctc ggagggggag cgaccgggga tctcgtggat ggtcgtatgg cggcccgcgc
     2101 cgtaccggtc gcgcccgaag gagccgagcg cgccgtccat gacgtcgttg aggcgatcga
     2161 tctcgttcgg tttgaggaag ctctccacgg tccggatgga cagcgtctcg gcgatgtgga
     2221 tcactgctcg cctccatcgc tggagcgggc ggcttcggtc gcgcaggcac agcgggtgga
     2281 cggcggggca gaggcggcct cggccagggc ctctgtgagg acgtgcacgg cctgggcgag
     2341 gtcctcgaag tactcggcag gtgcgatgcc ggcagcgggt acgagatgga ggtcgagcgt
     2401 cgggtacgcc cggccggtgg tgcggcaggt gagctcgctg cggccgagga ccagggaaca
     2461 ggtcccgggc agagagggct cggctcggtc agcggcccgg cacaggcgcg ctgccgtacg
     2521 cgcgtactcg tcgcggtcgc gcggcaggat gccgaccgag aggaagcggg gctcggctcc
     2581 ggggaggtcg gcgtacgcgt ggccttggca gctgtcatag gtgatggcgt tccagcctgc
     2641 ggtgagtgcg tcgacgaccg ggcggatgcc gggttcgatg ccctcgtacc actggggatg
     2701 gtgggggtcg agatcgtctg cctcgtgcac gccggggaga ccgaccgtgt tgatgttgcc
     2761 ctgggcgctg acctgcaggc gtgcgggctt gcggggcaca gtggggtcgt cccagcgggc
     2821 catgaacgcc gcgacgtgct gcatgtcatt gggtcggacg ggacgccagc gaagccggga
     2881 acaggaggcg ccgggcggga aactcggctg ggcgaggagg gcggcgacgc cgtcgatcag
     2941 gcgcatgcgg tggtcgcagt acgcgtcttc gtcgcccgca gcggcgaagc ggaggcggac
     3001 cgccgggcag cctgtgccgc aggaatcgcg gtagtcgcag gtcgtgcact tcgtgaccaa
     3061 ggagcgtgcc tgctgaagca agggagagcc gccctgggcg ccggctatgt ccgcctcggc
     3121 gtgtatgtcg ccgagtgcgg cgaggctggc ctgcggccag ggcagctcgt cacagcttcc
     3181 caggcggtcg tcgggataga gggtgaggac gtggtcgcac ttcaagtcag agaagtggca
     3241 ggaacgcgtc tgcagaccct tcagacggcg gatgacggag acgacgggct ccagcttgac
     3301 gcggcggaac aggccgtcgg caacccagtg gtgggcggcc tccaacacga agtcggcgta
     3361 ctgccgaggc gtgacggccc aggccgggcc ggtggggccg atggctcgtc gctggagtgc
     3421 ccgactggtc ggcgcacggg atccgaccac catggtcgac cgggtgaccg ccgcgtcgaa
     3481 acacggcacc aggctgaccg tcgtcacggc gggaaaggag gcgaggtgct ccatgacctc
     3541 ggaggcccgg ccgaggacgt acggggtgac ggcgcagatg acgccgacgt tgcgttcccg
     3601 acggccgagg agctccaggg cttcgaccac tcgggggtac gtggggcggc cgtcgtaccc
     3661 gacgcgccac gagttcccaa gcgcgtcccc gtcgagggag atgccgatct ccagctccgg
     3721 gcagtgctgc tcgaacaggt ccagccacgc gtcgtcgagc cggaggccgt tggtctggag
     3781 gctcacgcgg aggacgttcg gctgtgcggc gagcgcgtcc aggatctccg cgatccgctc
     3841 ccggccggcg gtcaggggct ccccgccgtg gagttcgatg ctgagcgggc gcccggagaa
     3901 gatcgaaccg aggcggtgga cctgtgccgc gttgatccgg gcgccgcccg gtgcctcctt
     3961 gcgcttctcg aagcagtaca ggcagtcgat gtcgcaggtc tctccccgga gcttgaggat
     4021 gacggagacc gccgtgtccg gcccggtgtt cgacaacggg gcgtagagac tctccaggtc
     4081 cgtgggggcg gtgcgggtga cgggcatcag aagcctcccg aggaggagag gcgcggtcta
     4141 cgcgccatcg gtggagaccg cggacagcca tccgagaagc tgtccgccgg tgatggggat
     4201 gtggacgtcg ccgcggcgaa ggaaccaccc gtcggcgtac cgctggggca gccagccggc
     4261 gtctggggcg cccagactgg gaggcttctg cagcgggtcg tcgacgggcc agcagcccag
     4321 gagcgctctg gccacgcgtc gctgaaccgg acggaaccac tcccacgtct ccgcgcgagc
     4381 cgggttgatc gacgggcggg gcggcgcgcc ggtgagcagc ggcagccact tgtcgcccag
     4441 gacgggatgg ccggccgccg cgcagtcgag cgcggcgaga caggtctcca gcttccggca
     4501 tacgacgccg accgattcgg ccaggccgtc ctcgacgagg ccggtcaggt cctcggcgag
     4561 actggccgcc acttcggcct ggtcggcgac cgcccaccgt cggtagccct ggcgctcctc
     4621 gggagcgagc accggattcc agcgtccgga gccgtaggag agagcggtgc gcaggcacat
     4681 gaggtcgtgc atcgaggcgc gtacccggcg gaaggagctg aggtcgtcgc ggcggacgtc
     4741 gaaggagcgg aacaggtgac ggagttcctc cgcccgctgc ggcgccgtcg cctggaggtc
     4801 gacacggacg ccgtccacga tgcgggactc ccacaccgga agggtgccgt ccacgatgcc
     4861 acgcaggtcg atgtcgctcg ccgcgtgggc gaagccgcag gcgagggctc cctccagcca
     4921 gacctcacga gcctcgccgg acgcgagcag agactgggcg actctgtcgg cgatctcccg
     4981 gcgcagtcgt gccgatgggt tcaccggtgc cctccttcga tcaggatctt gtcggcggcg
     5041 gtgatttcct tgaggagatc gatggcccat cggtcgagtg cgccgcgcac gtcggagcgc
     5101 tgggcgccga tgtggggcga ggccaggagg ttgagcggcg tcgtggagcc ggtgaggagt
     5161 ggcaggtgct cccgctcgac cgggtcgagg gcgaggcccg agagcctccc gtccgccagc
     5221 gcccgcaggc aggccgcgac gtcgagggtc tccagccgcc cggcgcagat cagcagaggc
     5281 cgctgcggag tgacacgtgc gaggaagtcc tcgccgatga gctgttcggt cgtgggacgc
     5341 aacggcagag cgatcacatg tacctgcgac tgctccatga gggctgtcgg cgacagctca
     5401 cgcagaccgg gagagttcga cggccacgcg gcgaaggccg tgcggtccac gtagggagcg
     5461 agggcccact cggcggccag ccccaccggg cccgcgcccc agattcctgc ggtcagggtg
     5521 ccgagtggtg ctcccatgca cgcatgcttc tcgtgctggc cgagcagcag cgcgtgctgc
     5581 cccaagggga tccgccgggc cagggcgagg gcagcggcga ggacccactc tcccacggcg
     5641 cccgcgccgg cctcggcgtt gcggtgcagt gtgatgccac ggcgttggag ggcgcttacg
     5701 tcgatgtggt cgatgccgga gccggtccgt acgacgtgcc gcaggcgggg cagtgcgtcg
     5761 agctcccgct cgccgagtcg gacaccggaa cgcaggacga ccacggccgt gtcggctggc
     5821 agaggccact taaggtcgag aaaatcgtgc acgaggacgc cgggcagggc gcggcggatc
     5881 gcacccgcat ccgccgctcc gcgcaccacg aggactgcgc tcatccgagg gtccccggct
     5941 tctcgtaccg gccgaaggcg agatcaccct cgccgacgac gacggtcacg ggcgatggtg
     6001 cgccgaagta cgcgtcgcag gcgcgcttca cccccgggag cccgtcccag gctcgcggat
     6061 tgaccgccgt gtccgcgtag tcgtcgacga ggagtacgcc cgtcggcacg aggcggggga
     6121 cgcagtgcgt gaatcccgtg agagtcgagt cgtagaagtc gccgtccagg taggcaaacg
     6181 cgatctcgct gggtaactcc ttgggaaggg tctcgtcgaa ccatcccggg tggatgaccg
     6241 gcgtcggcct gtcccaggcc gtgtgcgtgg cgcgtacgtc gtcgggggac gaccggagct
     6301 cgcccgccgc caggtggtcc gagtcctcgt cgccgggcgc gggcatgccc tggaaggagt
     6361 cgtagacgtg gatctcgcgg tcgcggtcgc ccagcgagtc aagcacgcta cggatccaga
     6421 gggccatcgc acctctgtag cagccgagtt ccaccacagg tccgggcaga ccgcgggcgg
     6481 tcagagcagc gagctcgtcg gcgatcacgc ggagccggtc tgcacagacc gtcccggagt
     6541 gctcccgtag cagccactcc cgcagatcgt tcagcttcgg atccatgaag gtcaccacct
     6601 gtccacgaag gggtcggcga gctccccgtt caacgctgcc gacagcgggc ggttgatccg
     6661 gggcagcagg tacacgtcgc ccagacgttc cagcggaatc cactcgaagc ccacctggat
     6721 ggggtctggc ggttccggca tgcgcggctc ggcgtcgtcc acctgctcgg cgaggaagtt
     6781 gaactgaacc ttctgcacgt ccccgaactc gccctgccac gactcgggca cgtactcgac
     6841 gacgcacagc agatgccggg ccacgacctg gaggccggtc tcctgtgcga ccttgcggtt
     6901 cacggcttgg cgcaggtcct cgccgacctg ggccttgccg ccggggaggt tgtagtggaa
     6961 cccggtctcg tcgtcgtacg acagcagcag gacggcgccg tcgcgcacga tcgccgcctt
     7021 cacagagaca ctgatccgag gcagctcagg cgtcagaggc acgacagcgc ctccggttcg
     7081 ccgacgcgca tcaggtcgcc gacctccgcg agggaccccg cgacggtgga gcggaaactc
     7141 cctccgcgcc ggaactgacg agcggcggtg cgcatacccg cgagcgcggc acggctcagc
     7201 tggttcgcgt agatgcagag gctgaagccg gcctcgccga gctcggcggc gctcacgtcg
     7261 gggaacgccg tgggcacgct gaccagcggc acgccgtggt tccacgcacg tccgattgcc
     7321 cgcgcctgat caccggccgc gtcctttgag tggatgagga tcgcatccgc tccggcctcg
     7381 gcgtacgcct cggcgcgggc gatcgccgta gccatgccct cgccggcaat cagggcctcg
     7441 gtgcgggcca cgaccacgag gtcatcaccg gcgagcttcc gtatgcgccc cacctgctcg
     7501 cacagcagat cccggtcagc gaggctctgg gcacggtggg ccgcgaagct gttgcatttg
     7561 gggtacgcgc tgtcctcgac acacactgct gcggctccgg cgcgcatcag gtcgtacgcg
     7621 aaccgctccg ccgtgcgccc cgagccgccc gcgttgtcga tgtccacgat gacgggcagc
     7681 tcggtgacac ggccgagcga ggcgaccacg tcggacaggt cccgggggcc caggacgttg
     7741 gcgtccggca gcccggaggc cgcggacacc tccagaccgc tcacccacag ggcgtcgaag
     7801 cccgcttccg ccgcgacgtg cgcggcgagt gcgttcaccg caccgatcgc cagaagcggg
     7861 tgcttccgct cgctgtcgtc gagggtctcg cgcagacgcg tccccttcgg gtcgtcagcc
     7921 atggatcttt cctccttccg cgggggcggc gagcgacggc accagctgcc gttcgcgcag
     7981 tacgtcccag gcggcgagca gcatctcgga ccgtggccgg cgggcgtcca ggcggaccac
     8041 gtcgcccagg agcgggaact cgtcgggctt cgagaccacg gcctcgtagg tttcgcgaac
     8101 ccggctctgg acgtcgcgca cgtcccagtc ggcccgcacg gcgtcaccct gtcgggcctg
     8161 cgcccggctc atcgaggcgt cggtctccag gtccaggacg agcgtgatgt ccggggctac
     8221 ggtgagctgc gcggccagcg ccccgtacgt ctccgatgcc ctcatgccgt gcttcacggc
     8281 gaagaaggcc agctcgctga ggagccagcg atccgcgatc accggccggg ccgctcgctg
     8341 ggggagcacg aggcgatcca gcgtggcccg cttgtccgcc acgatcgcgg ataggtaggc
     8401 gtcgcggata ccggcgttcg gctggtactt accggtgacg atggcagcgg cctggtcggg
     8461 ggcgaggaag ttggtggtga gcacgcacag cggggtgacg ccgtagagcc cctcccagag
     8521 ccggaacaga cccttgcgca gcgtcgtctt gccggtgccg tcgagcccct cgatgacgat
     8581 gaacggatag cggtggttca ttcgacctgc cccgcccccg tgccgccggc gtacttggtg
     8641 aagcgacccc gccagcgggc cgtggtggac accaggtcca ccagccgcag ctctgccaac
     8701 tcgtcgataa ggcggggcag ctcgggctcg gcgcagatac cggcctcgat agcccggcag
     8761 tacgcggcgc ggagggtggg gtcgtcgacg gagccgcgca gcgccgcctc gatcactcgc
     8821 gtagccattc cgtaggccac ggtgcccacc gcggtgccca gggcctgctc atgcagcgtg
     8881 cccgggtgcg gctccaacgt gatgtggtgc accccgcggt ggcggatgac cgcgaagaag
     8941 cccacccacc atgcggcggc ggcgctgacg gcggtcacgg cgccgcacca ggccgccccg
     9001 gactgctccg cgaggaggtt ctgggcagcg gtgtcggcgg cgcggtgaag tgccccgcgc
     9061 cggttccgcg actccgctcc gtgtcgctgg ggcagctccc accagaagcc gagcccggcg
     9121 tcctcgagca gcgccatcgc ggactcgtcg cctgccggca gcggagacgg gcgctgggcc
     9181 agcaccgaga catcggcgct cggcacgtcc ggcagtgcct tctcttcggc gacggcagcc
     9241 cgccattcat cgagatggag atggagccgc tgggtcagca gcccgtccgc cagcgtctgc
     9301 caggcatgga tcagcggcgg cgaatcgggg ggcctgggcg gcagggtcaa ggaggtcaca
     9361 ggtcggatcc tcacgtgtcc ggggagtcgc ggcacgcggc tccggtcggt ggtgctccac
     9421 cacgatggcc gccatgaagg cccacgctta tgagcgttta tgagcctcac gagcggactg
     9481 tgtccgggtg gtcgcagagc gaggcagaat gccgaccatg gtcgacagcg gacaacggcg
     9541 gtgtacgcgc tgcggtgccc ttctcagccg cttcaacgcc ggtacacgat gcgcctcgtg
     9601 ccaggacggt ccggccgccc gccgggccga cccggccttc tggcgtgatc cgacggtccg
     9661 gcgagccgtg gccgcatggg aactcggcac cgtcgtcaag ctgttcagac agcacacggg
     9721 cctctcccag gccggtgtgg cgcggatggt caacatcgac caggccgagg tcagcagact
     9781 ggaacgcgga ctcaagcaga tccgtgaccg acggcagttc gtccagtgga ccgatgcgct
     9841 gggagttccg gaggagctgc tcggactcct gcccacggcc gatccgcaca tcccggactc
     9901 caagggccga ccgggggcgg cggatgtcgg agctcgtggg tacgcggcac tgcccgaagg
     9961 gccgggccag cttctgttac ccgccggccg gtccgtctcg acgacggcgc ttcccgtgct
    10021 gacccttccc gcggcctcct tcctcgggga cagcctgaga ctcgactccc gcccggagct
    10081 ggatgcctgg cgcaccatgc cgatgcgcgc gctcatcgtc gcgaaccgca cggtggacgg
    10141 ggcggtccgg cagttcgtca ccgacgcccg accaagcggc gtacgcgcca ccgcctccga
    10201 cccggtctac atccccgccg cgtacgaact ggacgacctg acctacggca tcctgtgggc
    10261 catgtcggga ttcgaggcag cactgctcgg cgacgaccag accctgcaca cctcgctcgc
    10321 ttcgttcacc gcttccccgg gcttgccgct cgcctccgat ctcggcctca ccgaagtctc
    10381 ccgaatgctg atcggctcgg agaccgcagc ccggtacatc ctgggccacc gtgaccacct
    10441 gggcgacgca cccgtctttt ggaccaggga acagcacggt gaggaggccg ccacctggct
    10501 gttcttccgg cacaagtacc agtacctgga acgaatggcg cccaagcgcc cgggcggtac
    10561 cagcggtcgg gggttctgcg tccccgaggc tgcggtcgcc tcctcgccgg cgtacgagcg
    10621 cgttctgctc tttctcgcca tcgcgctcat ggagtcctcc ggtatccgca cctgggtgac
    10681 ggacgacgga ggcttcgccc acaccgacgg cttcgcgctc tcccacgggc gacgcgccgt
    10741 catcgccaca tgggtaaggg ccgagggggc gtcccacctc gcggtcaccg cgcggccggg
    10801 agccctgcgg acgttcgccg atgtgacgag tcacgtcagc cagcactcgg ccacggcggc
    10861 tgagcaagcc ggacagcgcc ttgcggcaac ggctgagtac ctcggcctcg acgcctcctg
    10921 gctcggtcgc cggtgcgcac agttgtcggc cgtcggcacg gagcggctcg cccggccgcg
    10981 cagccggttg ctcggcctcg aagggctgga ggccgcctgc cggttcgtgg ccgagcaact
    11041 ggtgatcatt ccgcgtaccc ggacggcgcc gacccgatag cctgcctgaa ccactcgcga
    11101 ggccgtgctc ggcggcgtcc ggacagggga gcaggggata tgacggagtc ggtcaggaac
    11161 gtggcggtct tctccctcgg cggcacgatc gccatgacca ccgatcccac caccggaggc
    11221 gtcgtacctg cgctctcggc ccacgaactc ctcgccgcgg tacccgccct ggccacgagt
    11281 ggcatcggcc tcaaggtgcg ggacttccga cgtctgcccg gcgcctccct gaccttcgag
    11341 gatctcaccg cactgtcggc cgcgatcgcg gcggagctgg agaccggaga cgtcgacggc
    11401 gtcgtcatca cccagggcac cgacaccatc gaggagaccg ccttcctcct cgacctctac
    11461 cacggccacg agcagccggt cgtcgtcacc ggcgcgatgc gcaaccccac cctgcccggc
    11521 gctgacggtc cggccaatct ctacgccgca gtcctggccg cagctgaccc cggcctcagc
    11581 ggcgccgact gcctcgtcgt actcggcgac gaggtccact cggcacgggc cgtccgcaag
    11641 tcccacacca ccagccccgg tgccttcgcc tcaccggcgt gcggcccgat cgcgcggatc
    11701 gcggagaacc gggtccggat ggtgggcgga ctgccgcgcc gcggaccgct ggtcggcgcc
    11761 cccgaccgtg aggcgcgcgt cgggctctac accgtcaccc tcggcgacga cggcgccctg
    11821 ctcgacgtgt gggacggcaa ctgcgacgga ctcgtggtcg cggccttcgg tgtcggccac
    11881 gtcccggagc gcctcgtcga agggcttacc aagctcgcgt cccgcatccc cgtggtcctc
    11941 gcctcccgca tcggcaacgg acctgtcctg tccgacacgt acggcttccc cggctccgag
    12001 aaggacctac tcggacgagg actcatcagc gccggagacc tcggcccgta ccaggcgcgg
    12061 ctcctgctgc acgccctgct tgcccagggc gctgacgggg cgacggtccg cgagaccttc
    12121 accaccgcct ccacccgctg atcccatctc atcaggagac acccgcgcat gcgtgctcac
    12181 gagctgaccg tcggccgtac cttcggcgtc accttcgacc acggggagga cttcttcgag
    12241 gcgctgtcca ccttctgccg ggataacggc gtacggcagg gctacatccc ctcgttcatc
    12301 ggagccttcg cggaggccga gatcgtgggc gcctgcgaga agctcgcgga cccggacgca
    12361 ccggtctggg cgaagacgta cgtcaccaac gtcgaggcgt tcggcgccgg caccctcgcc
    12421 cacgacccag ccaccggcgg gatactcccg cacatccacg tctccgccgg cctgaaagcc
    12481 cagtcggccg acggcaggac gagccacctc ctgagcgcca aggtccagtt cctcagcgag
    12541 ctgctgatcg tggaggtcac gtcgcccacc atgacccggc cccggaatcc cgacctctac
    12601 gacgttccgc tgctcacgtt cggctgaccg gcaggagtcg gcggagccag gggtggccgg
    12661 gcgcgattac cttgatcgcg tccgccagcc aggcgcgtgc cggagcgtcc agcagtggca
    12721 gtaccgcttc gaagtcggcc tcgtccttgt cccgggtcgc cttcgccttg tagaagagct
    12781 gcacctcggg cgcgagatac gggatgcccg tcttgctcgt tcgcccgagt tggtcgatcg
    12841 ggaggcggat cgccgggtct cgccgcgaga cccactgggt gccctcggcc tcgtccagca
    12901 tgagctgcac cgaccagggc gc
//
