LOCUS       NZ_CP029254            28521 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Streptomyces spongiicola strain HNM0071 chromosome, complete genome.
ACCESSION   NZ_CP029254
VERSION     NZ_CP029254.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces spongiicola
  ORGANISM  Streptomyces spongiicola
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7180417)
  AUTHORS   Zhou,S. and Huang,X.
  TITLE     Complete genome sequence of the Type Strain of Streptomyces
            spongiicola HNM0071, the producer of staurosporine
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7180417)
  AUTHORS   Zhou,S. and Huang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2018) Institute of Tropical Agriculture and
            Forestry, Hainan University, No 58, Haikou, Hainan 570228, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: ABySS v. 2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 850.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003122365.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 01:04:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,008
            CDSs (total)                      :: 5,921
            Genes (coding)                    :: 5,739
            CDSs (with protein)               :: 5,739
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 182
            CDSs (without protein)            :: 182
            Pseudo Genes (ambiguous residues) :: 0 of 182
            Pseudo Genes (frameshifted)       :: 47 of 182
            Pseudo Genes (incomplete)         :: 161 of 182
            Pseudo Genes (internal stop)      :: 9 of 182
            Pseudo Genes (multiple problems)  :: 32 of 182
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:10:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1841836
            Orig. end                         :: 1870357
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029254.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..28521
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="betalactone"
                     /product="butyrolactone"
                     /region_number="7"
                     /rules="(HMGL-like and AMP-binding)"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..28521
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /detection_rules="AfsA"
                     /kind="neighbouring"
                     /product="betalactone"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..27666
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27666
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:17666](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..17666)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    722..737
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.39"
                     /tool="antismash"
     misc_feature    complement(1091..1106)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.15"
                     /tool="antismash"
     gene            complement(1449..2063)
                     /locus_tag="DDQ41_RS08000"
                     /old_locus_tag="DDQ41_08000"
     CDS             complement(1449..2063)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019765186.1"
                     /locus_tag="DDQ41_RS08000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08000"
                     /product="DUF2017 domain-containing protein"
                     /protein_id="WP_109293854.1"
                     /transl_table=11
                     /translation="MAGQFEALPGGGAAVALDEVEISILRSLAVQLLELIGPGDEPAEG
                     EDPLAALFAEGPSEPPSDPALARLFPDAYARPGAGRGADGAEGEDEELRALSAEFRRFT
                     ENELRARKRDDVLAVVRGLDALTVTGEGGAVLKLTAEDSLRWLGALNDLRLTIGTRLQV
                     TDDDETGDLYRLPDSDPRKPMVMAYLWLGVLQETLVETLTP"
     gene            complement(2063..2374)
                     /gene="clpS"
                     /locus_tag="DDQ41_RS08005"
                     /old_locus_tag="DDQ41_08005"
     CDS             complement(2063..2374)
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="clpS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139419.1"
                     /locus_tag="DDQ41_RS08005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08005"
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="WP_109293855.1"
                     /transl_table=11
                     /translation="MGGVTVPLEIEQTRSAEETFAVPEPDVPWVTIVHNDPVNLMSYVT
                     YVFQAYFGYSKDKAHKLMLDVHHKGRAVVSSGTREEMERDVQAMHGYGLWATLSQERQ"
     misc_feature    2426..2446
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 23.76"
                     /tool="antismash"
     gene            2466..3797
                     /locus_tag="DDQ41_RS08010"
                     /old_locus_tag="DDQ41_08010"
     CDS             2466..3797
                     /EC_number="6.3.4.21"
                     /GO_function="GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA]"
                     /GO_function="GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891601.1"
                     /locus_tag="DDQ41_RS08010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08010"
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="WP_109293856.1"
                     /transl_table=11
                     /translation="MNTADLGLPVSVPSTALFTDQYEFTMLQAALKAGTADRRSVFEVF
                     TRRLPEGRRYGVVAGTGRVLDAVDNFRFDEDVLGFLRDGGIVDEPTIQWLSDYRFGGDI
                     HGYPEGEVYFPGSPIMRVEGSFAECVLLETVILSVLNHDSAIAAAASRMSAAAGDRRLI
                     EMGARRTHELAAVASARAAYIGGFHSTSDLAAGFRYGIPTVGTSAHAFTLLHDTERDAF
                     RAQVDSLGRGTTLLVDTYDVGEAVVAAVEIAGTGLGAVRIDSGDLLMVAHRVRRQLDDL
                     GARDTKIVVTSDLDEYAIASLAAAPVDAYGVGTQLVTGSGHPTCSMVYKLVARAGSADP
                     GAPLVPVAKKSAGGKLSVGGRKWAARRRDEHGVAEAEVLGTGPVPEPLVDRQLLTELVK
                     GGEVVARESLDTARERHTAARAALPISATQLSRGEPVIPTEYLV"
     gene            3986..4570
                     /locus_tag="DDQ41_RS08015"
                     /old_locus_tag="DDQ41_08015"
     CDS             3986..4570
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948006.1"
                     /locus_tag="DDQ41_RS08015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08015"
                     /product="nicotinamidase"
                     /protein_id="WP_109293857.1"
                     /transl_table=11
                     /translation="MHRALIVVDVQNDFCEGGSLAVSGGADVAAAITDYIGEAQPGYSH
                     VVATRDHHIDPGDHFSEQPDYVDSWPAHCVAGTEGVGFHPNFAPAVACGSIDAVFDKGA
                     HEAAYSGFEGTDENGTSLAEWLRSHDVTEVDIVGIATDHCVRATSLDAVREGFRTHVLL
                     DLTAGVSKETTDRALEEMRQAGVDLSGKPVL"
     misc_feature    complement(3998..4011)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.86"
                     /tool="antismash"
     gene            complement(4879..5193)
                     /locus_tag="DDQ41_RS08020"
                     /old_locus_tag="DDQ41_08020"
     CDS             complement(4879..5193)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046268.1"
                     /locus_tag="DDQ41_RS08020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08020"
                     /product="hypothetical protein"
                     /protein_id="WP_109293858.1"
                     /transl_table=11
                     /translation="MPGGGFCKLPGGSVVVAIGLPDPAGGGRTVRVLVHAANRARALTR
                     LRNLGLRAVYLRGNAEPPTPDEITAVLHHPEGLLWRTQEPRSQELWHPIRALLRPAGGG
                     "
     gene            complement(5782..6999)
                     /locus_tag="DDQ41_RS08030"
                     /old_locus_tag="DDQ41_08030"
     CDS             complement(5782..6999)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526414.1"
                     /locus_tag="DDQ41_RS08030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08030"
                     /product="MFS transporter"
                     /protein_id="WP_109293860.1"
                     /transl_table=11
                     /translation="MTTSHTESQTDTPSAQGGKLPMSPLLALCTAAFIGILTEALPAGV
                     LPEMARDLSVSESAAGQTLTIYAIATGLSAIPMSMATATWRRKRLLLIAVTTFAVANVV
                     TAMSSNYALTMVFRLAAGVAAAVVWAELVGYARRLAPPHLAGRAIAITMAGIPLALSLG
                     IPVGTFLGKVFGWRLTFGLVALVSVLLLAWISASVPDHPGQQPGKRASILGALKLPGVV
                     SVLFVVAAYVLAHNILYTYIATFLDEHDMGGSRDIVLLVFGLASMVSIFITGALVDRRL
                     RSLTLGSAVLFLVAAGLLAILADIGAAVYVAMVLWGLGWGGMATLLQTAVTDAGGDRGQ
                     ALLVTTWNSFMAGGGAVGGILLGALGPDSFPWSVLILLGPVLLVVTGARAHGFPAKRPG
                     METTTP"
     gene            7060..7512
                     /locus_tag="DDQ41_RS08035"
                     /old_locus_tag="DDQ41_08035"
     CDS             7060..7512
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432715.1"
                     /locus_tag="DDQ41_RS08035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08035"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_109293861.1"
                     /transl_table=11
                     /translation="MRIGELAERTGTPRRMLRYYEEQGLLVPDRSPNGYREYCERSVDR
                     VLQIRGLLDSGLPTRIIKQVLPCLKLPRAIHVTDAAPETIATLERERDRMTRRIECLVR
                     SRDAISEYVEAVRRNRPRPAAEPPVAPVTSAASAASATDYALPLSA"
     gene            complement(7488..8387)
                     /locus_tag="DDQ41_RS08040"
                     /old_locus_tag="DDQ41_08040"
     CDS             complement(7488..8387)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609643.1"
                     /locus_tag="DDQ41_RS08040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08040"
                     /product="fumarylacetoacetate (FAA) hydrolase"
                     /protein_id="WP_109297612.1"
                     /transl_table=11
                     /translation="MSTVFECEYRGVRYAGLGIPAAGEPHTLHRVTDGQLRAALVGGGG
                     PEALRAAVTEATETVEADLGDPELRFLPPLLPTGSNNALINGFMGTHRSKFDRDPEPDE
                     EFTPPNYYIKGFGSWLRMPDEPLITPADPIWLLEEPEVALVYVNDDQGVPHYAGYTFGN
                     DLNDIGLHLKNPWAWTPYAKLCETSLTPWLFPDPPPRQVTGRVVIEREGARAWEGPFSC
                     GADSLYHRVDEMTDYLFSYPALRRPGLVNYLLLGADKATYHDGFRIEDGDRMVIDVTSH
                     GVVLANTVQCGQADSGSA"
     gene            complement(8521..9789)
                     /locus_tag="DDQ41_RS08045"
                     /old_locus_tag="DDQ41_08045"
     CDS             complement(8521..9789)
                     /NRPS_PKS="Domain: Aminotran_1_2 (27-378). E-value:
                     3.3e-44. Score: 143.4. Matches aSDomain:
                     nrpspksdomains_DDQ41_RS08045_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609642.1"
                     /locus_tag="DDQ41_RS08045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08045"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_217364424.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.2e-42, bitscore:
                     143.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPVPVAMSATLAADEALARRRRAGEEVLSLASGEIGLPVLTVL
                     RERLAEASGRNAYGPVAGSRELRAAAAGYWARRGLDTDPDLVVSGPGSKPLLFALLPAV
                     GGDVVMPVPSWVSYAAQARLAGRRPIAVPTLPGQGGVPDPEALRARVAQARAEGLDPRC
                     VVVTLPDNPTGTIADPATVQRLGEAARELDLIIISDEIYCDLVFDPADRAVSPAVFAPE
                     RTVVTTGLTKNLALGGWRTGVARLPDGPAGREVRGRLLAIASQIWSSTAAPVQAAAAYA
                     LTEPPEVVEWVATARRLHGTVVRAVADRFTAAGAVLAPVRATCYLYPDFEPLRDHLGAA
                     HGVHDGDALAALLARRHGVGLLPGSAFGESRRPLRVRAATSRLYGETDAERTEALSAED
                     PLRLPWIRRSLDRVAEVLDDLTR"
     aSDomain        complement(8656..9708)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DDQ41_RS08045_Aminotran_1_2.1"
                     /evalue="3.30E-44"
                     /label="DDQ41_RS08045_Aminotran_1_2.1"
                     /locus_tag="DDQ41_RS08045"
                     /protein_end="378"
                     /protein_start="27"
                     /score="143.4"
                     /tool="antismash"
                     /translation="EVLSLASGEIGLPVLTVLRERLAEASGRNAYGPVAGSRELRAAAA
                     GYWARRGLDTDPDLVVSGPGSKPLLFALLPAVGGDVVMPVPSWVSYAAQARLAGRRPIA
                     VPTLPGQGGVPDPEALRARVAQARAEGLDPRCVVVTLPDNPTGTIADPATVQRLGEAAR
                     ELDLIIISDEIYCDLVFDPADRAVSPAVFAPERTVVTTGLTKNLALGGWRTGVARLPDG
                     PAGREVRGRLLAIASQIWSSTAAPVQAAAAYALTEPPEVVEWVATARRLHGTVVRAVAD
                     RFTAAGAVLAPVRATCYLYPDFEPLRDHLGAAHGVHDGDALAALLARRHGVGLLPGSAF
                     GESRRPLRVRA"
     gene            complement(10001..11656)
                     /locus_tag="DDQ41_RS08050"
                     /old_locus_tag="DDQ41_08050"
     CDS             complement(10001..11656)
                     /NRPS_PKS="Domain: AMP-binding (36-452). E-value: 5.1e-83.
                     Score: 270.8. Matches aSDomain:
                     nrpspksdomains_DDQ41_RS08050_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947777.1"
                     /locus_tag="DDQ41_RS08050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08050"
                     /product="AMP-binding protein"
                     /protein_id="WP_109293862.1"
                     /sec_met_domain="AMP-binding (E-value: 7.1e-86, bitscore:
                     286.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTVRTPVSAPTADRMAEYRRRGWWRDETFLDDLRRQARERPR
                     KLAIAGRRLGEARTDTLDYAELARLTDRFAGALLELGVERGDVVAVQLPNRWEMVPLMF
                     ACTAVGAVICPIAPVCREEELHHRLALTEARVCVTVAEWDGYPLAETINALRHELPLEH
                     VVVVDGHAPEGAVDFHDHFVSAHWEKQRTGDLEGRALRPDEPFVVLFTSGTTGFSKGVV
                     HSQNTVHSGVRGYADTFLLRDDMVVVVTTPLVHYSGFGQGVLAGVMLGGTIAFQDGPDH
                     VGLLDLVERYGATLLYGPPPTLSGVAAAQQTEPRDVSSLRHTITGAAPVLQELVDELRD
                     TFGARTYSVWGMSEFGPVTITRLDYNQDWAAHSHGRPIDSMEIRIDQCHDAGRRAPVGR
                     LRVRGASQALGYYKQQDAFDSELTSDGWFDTGDVAREDGRGGIRILGRSRDTILRDGIV
                     VPMAELEAILSRHPGVAEAALLGPTGQVDDPILAVAVPRGGARPTLPEIRDHLRDHGQD
                     PRFFPERLEVVDVLPKTLTGKVRKVELRERFSGG"
     aSDomain        complement(10301..11548)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DDQ41_RS08050_AMP-binding.1"
                     /evalue="5.10E-83"
                     /label="DDQ41_RS08050_AMP-binding.1"
                     /locus_tag="DDQ41_RS08050"
                     /protein_end="452"
                     /protein_start="36"
                     /score="270.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RRQARERPRKLAIAGRRLGEARTDTLDYAELARLTDRFAGALLEL
                     GVERGDVVAVQLPNRWEMVPLMFACTAVGAVICPIAPVCREEELHHRLALTEARVCVTV
                     AEWDGYPLAETINALRHELPLEHVVVVDGHAPEGAVDFHDHFVSAHWEKQRTGDLEGRA
                     LRPDEPFVVLFTSGTTGFSKGVVHSQNTVHSGVRGYADTFLLRDDMVVVVTTPLVHYSG
                     FGQGVLAGVMLGGTIAFQDGPDHVGLLDLVERYGATLLYGPPPTLSGVAAAQQTEPRDV
                     SSLRHTITGAAPVLQELVDELRDTFGARTYSVWGMSEFGPVTITRLDYNQDWAAHSHGR
                     PIDSMEIRIDQCHDAGRRAPVGRLRVRGASQALGYYKQQDAFDSELTSDGWFDTGDVAR
                     EDGRGGIRILGRSRDTI"
     CDS_motif       complement(10985..11035)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DDQ41_RS08050_0001"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="DDQ41_RS08050"
                     /protein_end="224"
                     /protein_start="207"
                     /score="17.8"
                     /tool="antismash"
                     /translation="VLFTSGTTGFSKGVVHS"
     gene            complement(11656..12771)
                     /locus_tag="DDQ41_RS08055"
                     /old_locus_tag="DDQ41_08055"
     CDS             complement(11656..12771)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609640.1"
                     /locus_tag="DDQ41_RS08055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08055"
                     /product="Glu/Leu/Phe/Val dehydrogenase dimerization
                     domain-containing protein"
                     /protein_id="WP_109293863.1"
                     /transl_table=11
                     /translation="MSNVDDPQQPAFTVHLNGSGGSLKGWVVVDTLVDGLAMGGVRMTP
                     GVTEGEVRGLARDMTDKFTLAGLRIGGAKGGIVSDGGDREETFRTFGRTVKPLLHGGIH
                     LGIDMGVTAADRAVFFDEAGYDPRHRLGAPDMPIDWRTYYEPLIDATGHGVGVAAVTAL
                     EASRRTEPARVVVQGFGAVGRAVARFLEDRGHVIAGVADIEGTVSADRLPVGDLLAITD
                     AYGRIDRSRLPQHVTVANEPDAWLDVDADVLILAAQKHALNADNTHRLRARLVVEGANL
                     ASSAEAREKAAASGAALVPGVIANIGGAGAAALAVTRVVPFGLAADARRQWVFDWVADR
                     VRRNTRDLLEIAASAAGDPLPELIAVRRKEL"
     gene            complement(12925..13488)
                     /locus_tag="DDQ41_RS08060"
                     /old_locus_tag="DDQ41_08060"
     CDS             complement(12925..13488)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609639.1"
                     /locus_tag="DDQ41_RS08060"
                     /note="Members of this family of hydrolases with an active
                     site Cys residue belong to MEROPS family C26.; Members of
                     this family of hydrolases with an active site Cys residue
                     belong to MEROPS family C26.; Members of this family of
                     hydrolases with an active site Cys residue belong to MEROPS
                     family C26; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08060"
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="WP_109293864.1"
                     /transl_table=11
                     /translation="MAKSRVLVVDNGTLSLKQLRARFEHLGSETDAVNVNSVPTGLGGR
                     YQAIVLSGTKVRAYDTGFYRPLVDLVMGADVPVLGICGGMQLIAVAAGGRLAEGPQRVG
                     GHEAQVEPDEPLFTYVKPTVTVFHRHTLYLREAPEGFRSIGRSAHAPVEFLRSDDGRIH
                     GAQAHLEFRGDGLEILRGFARLYE"
     gene            complement(13499..14302)
                     /locus_tag="DDQ41_RS08065"
                     /old_locus_tag="DDQ41_08065"
     CDS             complement(13499..14302)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1174: acetylglutamate kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947774.1"
                     /locus_tag="DDQ41_RS08065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08065"
                     /product="acetylglutamate kinase"
                     /protein_id="WP_109293865.1"
                     /transl_table=11
                     /translation="MSGTHPGRVPTVVKLGGSCLDDLADTWWDDLARHGRERPLVLVHG
                     WSRPLRELDPRYRDPSAVLRDRYGNQSRWTTPEVIADIKTVSARMSEDILGRLERRGIA
                     AERVLGSDGLVAAGEGERWWWRDKQLVELENLVGPITGVDPTGLKNLQPGHAHLVTPLA
                     RNDGGQEVNTDADRAAAALAAATGAGDLVLVTDVAHLLVDGEPVAAISARAAAGFRDRG
                     ATGGMRKKLRAAGEALDGGVDRVVIGSAPVTELLAGRTGTVITRS"
     gene            complement(14299..15354)
                     /gene="argC"
                     /locus_tag="DDQ41_RS08070"
                     /old_locus_tag="DDQ41_08070"
     CDS             complement(14299..15354)
                     /EC_number="1.2.1.38"
                     /GO_function="GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070401 - NADP+ binding [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1219: N-acetyl-gamma-glutamyl-phosphate reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379927.1"
                     /locus_tag="DDQ41_RS08070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08070"
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="WP_109293866.1"
                     /transl_table=11
                     /translation="MTRVGVVGASGLAGGELIRLITQHPDLELTFLGGSSNIGRRPAEL
                     HPGLRLDLGLTVQPVTEEIAGQVDAVLLATPAPVSAELAALLADRVPAVLDLSGAFRIR
                     TPELHDRWYPDVKRRTDLADRFVYGVPELVGDQMADAALISLPGCYATSMTLALAPLTL
                     GLGLNLKTVVVDGKSGSSGGGLHLRTADLHPLRNGAIAPYAPVGHRHAAEVGDFLERGK
                     RGGVGRLSMSAYGVSHVRGLLTSSYVFTDESVDQRELQRAYLRFYKDHRFVRVRRNTET
                     LIPVPDPQAVLGSNYCDVTVMHDEDGERIVVLAALDNLVKGAAGQAVQALNIRFGLPEE
                     TGLTMQPVMPA"
     gene            complement(15351..16202)
                     /locus_tag="DDQ41_RS08075"
                     /old_locus_tag="DDQ41_08075"
     CDS             complement(15351..16202)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947772.1"
                     /locus_tag="DDQ41_RS08075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08075"
                     /product="RimK family alpha-L-glutamate ligase"
                     /protein_id="WP_109293867.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 5.1e-07, bitscore:
                     28.3, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 5.6e-23, bitscore: 80.0,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 2.9e-05, bitscore:
                     22.1, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATVAIVADRIGWEERRLIEAAPEAGLVVDWVNDESLCLGHQDA
                     PSLTGYDAVLVRSRSYTRGGLIATLAEASGIRTINTASAIRACENKLELRAVLHRAGVP
                     AGDFRLVLSRRDFEQALKDVPPPVVLKPVFGGMGKRVTLIRDTDTAQSVYDYVEDLGHG
                     FEQASLVEPYLDGGTSVRCLVVGREPVATAEFASAGGDWRSNAALGNRSRALDHDPAIT
                     KIVDGVVDALGPGIYGIDLFQVPGGHVVNEVNHAPAFKAIAAATGADIPRAVARHLQET
                     LT"
     gene            complement(16231..16416)
                     /locus_tag="DDQ41_RS08080"
                     /old_locus_tag="DDQ41_08080"
     CDS             complement(16231..16416)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967615.1"
                     /locus_tag="DDQ41_RS08080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08080"
                     /product="lysine biosynthesis protein LysW"
                     /protein_id="WP_109293868.1"
                     /transl_table=11
                     /translation="MTTATLAGSCPECETDLTVPPMVPGETLSCPECMLTLRVEDVTNG
                     KVTLQMVEVQLRDWGQ"
     gene            complement(16512..17666)
                     /locus_tag="DDQ41_RS08085"
                     /old_locus_tag="DDQ41_08085"
     CDS             complement(16512..17666)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967613.1"
                     /locus_tag="DDQ41_RS08085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08085"
                     /product="isopropylmalate synthase"
                     /protein_id="WP_109293869.1"
                     /sec_met_domain="HMGL-like (E-value: 5e-48, bitscore:
                     162.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGTEPEGALPQGRPRLSDATLRDSAHMAGVEFRPGDAAAMARLL
                     VRTGVELVEVGMVSGPNSKDADLILATHEAVGPERSMTLVVVRDRRQVATALAEAERLG
                     VRHIMYSIPTSEQHAKLKLGSPSARFLHALAGSAITQAKERGFHVTFSGEDGARTPRER
                     LVPYVTAGFEAGADRFRLAETVACLSPWQMERVIAGLTAIEGSEIEIHSHNMLGMAVAN
                     SLAAVRAGAQWISATVGGIGERGGNAPLAELLTALRVVHGDTRFDLSGLTELSRIALGG
                     AGLGEAFQSGPTTPHAFAYELPGQLTHPEAYETLPAELVGNQRELRVRTRLTPALVTWA
                     LRESGVLVDVEAFTAWLTERQERDGGPLLDRDAIRKAAIDFQAA"
     cand_cluster    17613..28521
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    17613..28521
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[22612:23521](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      22613..23521
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
     misc_feature    complement(17803..17818)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.95"
                     /tool="antismash"
     gene            17971..19128
                     /locus_tag="DDQ41_RS08090"
                     /old_locus_tag="DDQ41_08090"
     CDS             17971..19128
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012656.5"
                     /locus_tag="DDQ41_RS08090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08090"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_109293870.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 5.2e-17, bitscore:
                     61.0, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.2e-19, bitscore:
                     67.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFPYSPGERGTEGALAEQTRELADRVVRPTAADRDRDRSWDPAL
                     FAELADARPGLTGPLVPGRLGGGGLTAAQTCAVLQGLGEGARDPGLALAAAVHAALVTV
                     PLRAFGTAAQQRRRLPRMASGEWVGALSLRQTQGAALAPAVTARPAPDGWVLDGALDLV
                     VGAPLARHFLIVAAHPDGSGRTAFLVDRGTAGLRVEDVRPEALRTCPWGGLALDGCHVP
                     HDAVLGSPHGAATEVEPLLAVLSWVFSSAPWLGVMRALTRDAVERVRGDRLFDRPLSHF
                     QSARLTLADMAIQCELAAGLLYRAAGQFDGGGRPSQRDAAAARLFVAGAARTVVEAAAG
                     LTGPADGTGDGLIERAHRDALFFGTVGGGAEVLRPVIAACELGLG"
     gene            19268..20509
                     /locus_tag="DDQ41_RS08095"
                     /old_locus_tag="DDQ41_08095"
     CDS             19268..20509
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012656.5"
                     /locus_tag="DDQ41_RS08095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08095"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_109293871.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 7.1e-11, bitscore:
                     41.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.8e-16, bitscore:
                     57.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 8.2e-29, bitscore:
                     99.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVHRHGTDAAPTFPGTAARAAETDLTARIPAQNWKEVVDSGYLR
                     LFHPPTVGGTGADGAAQVAAMESLARACPSTYWSATVSALLCANLISTYGDLRVHGQLL
                     EGLLSGRLLAAFAVVETTAGSDAGTYTTTVRPAGEPDGGFVIDGEKSRITNAPDADVAV
                     ALARREKAAGDDGPDWCLAFVDLRQPGVRRYDIPRMGLRGMPWGGLVFSDARVSAQDVV
                     PVPLDELSEGMTWGWLLVSVAAVAVAESALTASVRHAGERVSFGRPLAHMEGVQAQIAQ
                     SRAQIDAARLLARRAAGERAAGRSARSLIAMLKIYATEMAVDVTARAVQIHGASGVTQG
                     HEVERLYRDAQMNVIGAFASNRLREQVAEGMGLGPAVYEPFDWLRPSGLGDAAVGLDAS
                     DRSADASGRSAEAA"
     gene            complement(20630..21307)
                     /locus_tag="DDQ41_RS08100"
                     /old_locus_tag="DDQ41_08100"
     CDS             complement(20630..21307)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740558.1"
                     /locus_tag="DDQ41_RS08100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08100"
                     /product="response regulator transcription factor"
                     /protein_id="WP_109293872.1"
                     /transl_table=11
                     /translation="MAETGRFRVLVVEDSAELAEERVRELRRQGYVASRVESGAKALSA
                     HTQADLVLLDLDLPDIDGLEVCRLIREVDDKPIVSLTARDNELDRVLALQAGADDCVVV
                     SCGLREIMARIEAVLRRVYPRPEREPVLSVGPLRIDGATREIRLHGEPVDVTAKEFELL
                     HMLAANSESVVSRKELMARVWGSRWGDSSRTIDTHVRSLRAKLGSHGWIITVRGVGYRM
                     GRG"
     misc_feature    complement(20702..20704)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    21423..21436
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            complement(21822..22502)
                     /locus_tag="DDQ41_RS08105"
                     /old_locus_tag="DDQ41_08105"
     CDS             complement(21822..22502)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047020.1"
                     /locus_tag="DDQ41_RS08105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08105"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_281278220.1"
                     /transl_table=11
                     /translation="MARLDEGRRCGVAKQDRAIRTRNQILESMASLFNEVGYDAATIAA
                     LVERTGLTRGALYFHFASKEDIARAVLDEAVTREGLREQAFKVQEWVDLGLLLAYRVPR
                     EPILHAAIRLSVDPKARRLFGTRWPDWVAVGEGFLTEAKQRGELLPHADPAVVSRTVVG
                     SWTGVQLVSEAMSEDLDLAEEISVLYQLVLPNVVTPTVLARIDSSPYRAERLLKEQSRT
                     SAVE"
     gene            22613..23521
                     /locus_tag="DDQ41_RS08110"
                     /old_locus_tag="DDQ41_08110"
     CDS             22613..23521
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041195.1"
                     /locus_tag="DDQ41_RS08110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08110"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_109293874.1"
                     /sec_met_domain="AfsA (E-value: 1.1e-17, bitscore: 62.3,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGSTDASVSPLPRLHTGWREKIGEYTHLTHGATLLVGDWRKQGP
                     DTHLISVRWPSNNTTGGADPRLLAQTVRQCGLLVAHAAYGVPTGHHTLLHSLNITTEPG
                     FRAGEGASFEVRLTVTRAERRSSTLSMVLHIRSRDRTVAIADTVFAWVSPAAYRRMRGR
                     RLHVDWAGWPVPDPAAPHLVGRLHHGDVLLADGGSRDRWRLRNDVSNILLFDHPVDHVP
                     GLVLLEAAQQAAHALTYPDPVEFTDVSIEFARYVEFDEPCWLTVEPLTTLLPEWSSLRI
                     AGRQGERDVFRARLKGLRPAS"
     gene            complement(23659..24420)
                     /locus_tag="DDQ41_RS08115"
                     /old_locus_tag="DDQ41_08115"
     CDS             complement(23659..24420)
                     /EC_number="1.1.1.47"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-170). E-value: 3.1e-14. Score:
                     45.2. Matches aSDomain:
                     nrpspksdomains_DDQ41_RS08115_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155345.1"
                     /locus_tag="DDQ41_RS08115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08115"
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_109293875.1"
                     /sec_met_domain="adh_short (E-value: 6e-34, bitscore:
                     116.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 6.3e-29, bitscore:
                     100.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSELLTDKVVLITGASSGIGAAAARVFSREGAAVVLAARREERLA
                     AVVGELRAGGREAAYAVGDVTVSADAARVVDFAVTTYGRLDAAFNNAGVGGDRTPLHLM
                     PDEVYNAIMDVNVRGVWNCLRHEIAAMLPRGGGAIVNNSSVGGLVAIPAAAPYIASKHA
                     VVGLTRAAADEYAKQGIRVNAVAPGTTRSEITVDWFTRNPGLEEVAHSVTPQGRTAEPE
                     EIAAAVAWLLSDRCPFLTGAVLPVDGGFVNH"
     aSDomain        complement(23911..24396)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DDQ41_RS08115_PKS_KR.1"
                     /evalue="3.10E-14"
                     /label="DDQ41_RS08115_PKS_KR.1"
                     /locus_tag="DDQ41_RS08115"
                     /protein_end="170"
                     /protein_start="8"
                     /score="45.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLITGASSGIGAAAARVFSREGAAVVLAARREERLAAVVGELRA
                     GGREAAYAVGDVTVSADAARVVDFAVTTYGRLDAAFNNAGVGGDRTPLHLMPDEVYNAI
                     MDVNVRGVWNCLRHEIAAMLPRGGGAIVNNSSVGGLVAIPAAAPYIASKHAVVGLTRA"
     CDS_motif       complement(24301..24396)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DDQ41_RS08115_0001"
                     /evalue="1.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="DDQ41_RS08115"
                     /protein_end="40"
                     /protein_start="8"
                     /score="11.5"
                     /tool="antismash"
                     /translation="VVLITGASSGIGAAAARVFSREGAAVVLAARR"
     gene            complement(24787..27219)
                     /locus_tag="DDQ41_RS08120"
                     /old_locus_tag="DDQ41_08120"
     CDS             complement(24787..27219)
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958476.1"
                     /locus_tag="DDQ41_RS08120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08120"
                     /product="immune inhibitor A domain-containing protein"
                     /protein_id="WP_109293876.1"
                     /transl_table=11
                     /translation="MTGRTRAFRASAVLVALATTGATAAALTTAQADSRPSGAPGVERH
                     DPAPGSDHHEAHKGHVDHDLEGPFSEQQARQRQAALEQVISGDATVQQRGASKVVKLDD
                     KKYVELGREKTDKIFTILVEFGDKVDDTTMYDPDGDGPKPPVKKYGGTPGPLHNRIAQP
                     DRAVDNSTAWQKDYDRQHFQDLYFGEGEDEKGNPKHSLKTYYERTSSGRYSVEGTVSDW
                     VKVDWNEARYGSNYCGQSNCNNVWDAVRDGVTAWTADQKAKGRTDAQIKADLAQYDQWD
                     RYDFDADGDFNEPDGYIDHFQIVHAGEDESAGGGAEGPNALWAHRWYAYGTDAGRTGPA
                     DNRAGGTQIGDTGIWVGDYTMQPENGGLGVFAHEYGHDLGLPDLYDTSGGGENSTGFWS
                     LMSSGSWLGTGEDSIGDMPGDMTAWDKLQLGWLNYTKAKAATASKHKLGVAEYNTRNPQ
                     ALVVELPKKKVTTGVVEPAEGSMQWWSDMGDDLRNTLTRSLDLTGKSTASLELTGWWDI
                     EADYDYLYTEVSTDGGANWTAVDGTADGAAITRDASDKPALTGPSDTHRKLVYPLDAYA
                     GEKVDIRFRYQTDGGVAGKGFAADGIVVTADGAPLFSDDAETEAPGWTAKGFSRIGESF
                     TDEYEQYYIAENRQYVSYDQTLEVGPYNFGFKAPKDGWVEHFPYQNGLLIWLWDTSQKD
                     NNTSQHPGKGLILPVDANPGALKWADGTLMRNRIQSFDSTFSRFRSDALTLHKADVPTR
                     IAAHRGNSVFDDRKGVYWFEENPTAGVQVPDTNTRISIVKEPKKGQTITVRVGPSVR"
     misc_feature    complement(27361..27373)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.85"
                     /tool="antismash"
     gene            27676..27984
                     /locus_tag="DDQ41_RS08125"
                     /old_locus_tag="DDQ41_08125"
     CDS             27676..27984
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948003.1"
                     /locus_tag="DDQ41_RS08125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_08125"
                     /product="hypothetical protein"
                     /protein_id="WP_109293877.1"
                     /transl_table=11
                     /translation="MPRPTAAQLAYGSATVVVSTVAMLLLFRTTTALGVAVVAVAALAL
                     GLLVAVTVPAPGRAKAARTADRSRAAAFEDRSLPESARVPAARGAARHGVGQHSARR"
     misc_feature    28435..28452
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.94"
                     /tool="antismash"
ORIGIN
        1 gaactcggtc cacttcacga cggagaggat caccgcgagc gcgccgacat agaagatgat
       61 gatgcgccag ggcagcgtgt tgacggcctt ggggagtgtc ttctcggggt tctcggactc
      121 gccggcggtg acgccgacga gttcgacggc cagataggcg aacatgacgc cctggagggt
      181 catcaggctg gagccgatgc cgttggggaa gatcccgccg tgtgcccaga ggttggagac
      241 cgaagcggtg tcaccggcgt cggagaagcc gagggtgagc actccgagcc cgatcacgat
      301 catgccgatg atcgcggtga ccttgaccat cgagaaccag aactcgacct cgccgaagat
      361 cttcaccgag atcaggttga cgccgaagag caccaggagg aacaccaggg cgctgaccca
      421 ctgcggcatc cgggggaacc agaagtgcac gtagatggag gcggcggtga gttccgccat
      481 tccggtgacg acccacatga gccagtacgt ccagccggtg gcgaacccga agaacgggcc
      541 gaggaactcg cgggcgtact ccgcgaagga gcccgagacc ggccggtaga gcagcagttc
      601 gcccagcgcc cgcatgatga agaagatgac gacgcccgcc agggcgtaca tcaggatgat
      661 gccgggcccg gccttggcga tgttcgcccc cgcccccatg aagaggccca cgccgatggc
      721 accgccgatg gcgatcatct ggacctggcg gctgccgagc ccgcgctcgt agccttcccg
      781 cgaggtgccc ccggcctcgc cgtcgtgctt gccgacctgc aacgaggtca tggttgatgc
      841 gcctttctcc ataccgttcc gcgccgttgt gatgcggccg cggcccggtc ctgatccccc
      901 gggatgccga tggagtgcca ccggcggtcc gccggtccga acgcctccgg ggacatgggt
      961 ggcgccccgg caggtcgtga acatgtatca cggcgggaag cacgttcgat catccagaat
     1021 gtggcgcaac acacagaaaa aagcagacaa tccacccttg aaggccgaaa tcgaggtatg
     1081 cgagcaagaa gattttgatt ccgatttgac cgtttactga acgaagtcct cgcccaacgc
     1141 agtcctcacc caacgcagtc ctcgccgaac gaagccccga ccgaacgaag cccggacggc
     1201 gcgcaccgac gcgccgccgc ggacggtgac atccgccgtg cgcaccgcgg caccaccccg
     1261 tccccgcagc accgccttgc gccgccccgc gccgtcatga gccgcgaccg aaacgcgccc
     1321 cgcccgcacg accaggacgc ccacgaccag gacgcccacg accacgacgc ggcgtcctcc
     1381 cgggatgccg tgagaagccc cgcccggggc cgtacgggtg cgggccggac cggtgcgggc
     1441 cgggccggct acggggtcag cgtctcgacc agggtctcct ggagcacccc gagccagagg
     1501 taggccatga ccatcggctt gcgcggatcg gagtccggca gccggtagag gtctccggtc
     1561 tcgtcgtcgt cggtgacctg gagccgggtg ccgatggtca gccgcaggtc gttgagcgcg
     1621 ccgagccagc gcagcgagtc ctcggcggtg agcttcagca cggccccgcc ctcgcccgtc
     1681 acggtgagcg cgtcgagccc gcggacgacc gcgaggacgt cgtcgcgctt gcgggcacgc
     1741 agctcgttct ccgtgaaccg gcggaactcg gcggagagcg cccggagttc ctcgtcctcg
     1801 ccctcggccc cgtccgcacc gcgcccggcc ccgggcctgg cgtacgcgtc ggggaagagc
     1861 cgtgcgagcg cggggtcgga cggcggctcg ctcggcccct ccgcgaagag cgcggcgagc
     1921 gggtcctcgc cctcggcggg ctcgtcaccg gggccgatca gctccagcaa ctggacggcg
     1981 agcgagcgga ggatggagat ctcgacctcg tcgagcgcga cggccgcgcc gccgcccggc
     2041 agcgcctcga actgtcctgc catcactgac gttcctggga gagggtcgcc cacagcccgt
     2101 agccgtgcat ggcctgcacg tcgcgttcca tttcctcgcg ggtcccgctg gagacgaccg
     2161 cgcgtccctt gtggtggacg tcgagcatca gcttgtgggc cttgtccttg gagtagccga
     2221 agtacgcctg gaaaacatag gtgacatagc tcatcagatt gaccggatcg ttgtggacga
     2281 tcgtcaccca ggggacgtcg ggttcgggaa cggcgaacgt ctcctcggcc gaccgggtct
     2341 gctcgatctc taggggcaca gtcactccac ccatgctgcc acccgaggga cccggtcgca
     2401 caaacgcccc ggccgatacg acgacatctc gtcactctga cgaaatctgg gctagcatcg
     2461 cacatatgaa cactgcggat ctgggtctgc cggtctccgt gccgtcgacc gcgctcttca
     2521 ccgaccagta cgagttcacg atgctgcagg cggcgctgaa ggcgggcacc gcggaccgcc
     2581 gctcggtctt cgaggtcttc acccggcggc tgcccgaggg ccgccgctac ggcgtggtcg
     2641 ccggcaccgg gcgcgtcctg gacgccgtgg acaacttccg cttcgacgag gacgtgctcg
     2701 gcttcctgcg ggacggcggc atcgtggacg agccgacgat ccagtggctg tccgactacc
     2761 gcttcggcgg tgacatccac ggctacccgg agggcgaggt ctacttcccc ggctcgccga
     2821 tcatgcgcgt ggagggctcc ttcgcggagt gcgtgctgct ggagaccgtg atcctctcgg
     2881 tgctgaacca cgactcggcg atcgcggccg ccgcctcccg gatgtcggcc gccgcaggtg
     2941 accgtcggct catcgagatg ggcgcccggc gcacccacga gctcgccgcc gtcgcctccg
     3001 cacgcgcggc gtacatcggg ggcttccact ccacctccga cctcgccgcg ggcttccgct
     3061 acggcatccc cacggtgggc accagcgcgc acgcgttcac ccttctgcac gacaccgagc
     3121 gggacgcctt ccgcgcccag gtcgactcgc tcgggcgcgg gacgaccctg ctcgtggaca
     3181 cctacgacgt cggcgaggcc gtggtggcgg ccgtggagat cgccggcacc ggcctcgggg
     3241 ccgtccggat cgactcgggg gacctgctga tggtggccca ccgggtgcgc cggcagctcg
     3301 acgacctcgg cgcccgggac acgaagatcg tcgtgacgtc cgatctggac gagtacgcga
     3361 tcgcctccct ggccgccgcg cccgtggacg cctacggtgt gggtacgcag ctggtcaccg
     3421 gcagcggcca tcccacctgc tccatggtct acaagctggt cgcccgggcc gggtccgccg
     3481 atccgggcgc cccgctggtg ccggtggcga agaagtcggc gggcgggaag ctgtccgtcg
     3541 gcgggcgcaa gtgggcggcc cgcaggcggg acgagcacgg cgtcgccgag gccgaggtgc
     3601 tcggcaccgg accggtcccg gagccgctgg tcgaccggca gctgctgacg gagctggtca
     3661 agggaggtga ggtcgtcgcc cgtgagtcac tggacacggc acgcgagcgg cacaccgcgg
     3721 cccgcgccgc gctgccgatc tccgcgaccc agctgtcccg cggtgaaccg gtgatcccca
     3781 cggagtacct cgtgtgagcc cgccgaacac cgggtgaccc ggggcacgag ggcaccgccg
     3841 ctagcaggcg aaggcactct cccgcaaggc ggtcgaagtc tctaccctcg gaacgtcgcc
     3901 gccccaccgc cctgcaccgc cctgcaccgc cccggaccgc aacccgccgc cacccgcccg
     3961 ccgcacccac cgaaggacac ccgccatgca ccgcgcattg atcgtcgtcg acgttcagaa
     4021 cgacttctgc gaggggggca gcctcgcggt gtccgggggc gcggacgtcg ccgccgccat
     4081 caccgactac atcggcgagg cccagcccgg atacagccat gtggtggcca cccgggacca
     4141 ccacatcgac cccggggacc acttctcgga gcagccggac tacgtggact catggccggc
     4201 ccactgcgtc gccgggaccg agggcgtggg cttccacccg aacttcgcgc ccgcggtcgc
     4261 ctgcggctcg atcgacgcgg tcttcgacaa gggcgcccac gaggccgcgt acagcggctt
     4321 cgagggcacc gacgagaacg gcacgtccct ggcggagtgg ctgcgctccc acgatgtgac
     4381 cgaggtcgac atcgtgggca tcgccaccga ccactgtgtg cgcgccacct cgctggacgc
     4441 cgtccgcgag ggtttccgca cccatgtgct cctcgacctg accgccggag tctcgaagga
     4501 gacgaccgac cgggccctgg aggagatgcg gcaggcgggc gtggacctct ccggcaagcc
     4561 ggtcctctga cgcggccgcc ggaagccacc acaggcggct tcccgggttc cggtgcccgg
     4621 gcgcaccgca gcaccgcagc accgcagcac ccgggcgccg cgggcgcgcg gcgcccggcc
     4681 tgcggcgcac cgccccaggc tcccccggga gcgggtccgc cacccgtgcc ccgtcgcccg
     4741 cggagggcgg gcgggccggc cctcctccgc gggcgacggc gggaacaccg tccgctcgga
     4801 aggcgggcac ctgggccggc ccccgagaac cacgtggcgt gtggcgtgtg ggtcctgggc
     4861 acccggggcc cgcgggcgct accccccgcc cgccggccgc agcagggcgc ggatgggatg
     4921 ccacagctcc tgggagcgcg gctcctgggt gcgccagagc agaccctccg gatggtgcag
     4981 caccgccgtg atctcgtccg gcgtcggtgg ctccgcgttg ccgcgcagat acaccgcccg
     5041 cagccccagg ttccgcagtc gggtgagagc gcgagcacgg ttcgccgcat gcaccagcac
     5101 ccgcaccgtg cggccgccgc ctgccgggtc gggcagtcct atcgcgacca cgacgctgcc
     5161 tcctggcagc ttgcagaaac ctccgccggg cacgccgcac cactcccccg tgagctagct
     5221 gtcaataaga gtgtcatcag acgcacctaa acacgatcgg ccgccacccg ctagagggca
     5281 accctctccc ccgctctgac ctgctgtttt acccgcagag cagtgagact ccccctcttc
     5341 cgacatcacc gcacggcgtc tcgtccgccc gcttcttcat ttcgccgtca acaaaaggac
     5401 gccgtgcccc aacggcatcc cgccgctgcc gggccgccgt gcgggacctg ccgggcgcgg
     5461 acgggacacg gcggccgcgg aagccggtcg ccgccgcccc ggctcgggac tcggcagggg
     5521 gatcccgcta gttcgcccgc gcagccggaa gcccggcgac ccgcgacccg cgaccgacga
     5581 ccggcgaccg acgaccgacg accgacggta ggcagtaggc acggacgccg gcagtcggca
     5641 gtcggcagtc ggcagtcggc agtcggcagt cggcagtcgg cagtcggcgg gagagtcgga
     5701 cctgcgcgtc tcacgcaagc ccggtccggc acacggggga cgtgggtgcc ggaccggagt
     5761 tcctggtgtt ccgcgttgcc gtcagggcgt ggtcgtctcc ataccggggc gcttggcggg
     5821 gaagccgtga gcacgggcgc cggtcaccac cagcaggacg ggcccgagca ggatcagcac
     5881 actccacggg aaggagtcgg ggccgagggc gccgagcagg atgccgccga ccgcaccgcc
     5941 gcccgccatg aatgagttcc acgtggtgac cagcagggcc tgcccccggt cgccgcccgc
     6001 gtcggtgacg gcggtctgca gcagggtggc cataccgccc cagcccaggc cccacagcac
     6061 catcgcgaca tagaccgcgg caccgatgtc cgccaggatc gcgagcaggc cggcggccac
     6121 caggaacagc acggcgctgc cgagggtcag actccgcaac cggcggtcga cgagcgcgcc
     6181 ggtgatgaag atgctcacca tcgaggcgag gccgaagacc agcagcacga tgtcgcggga
     6241 accgcccatg tcgtgctcgt cgaggaaggt ggcgatgtag gtgtacagga tgttgtgggc
     6301 cagcacgtac gcggccacca cgaacagcac cgagaccacg ccgggcagct tcagcgcccc
     6361 caggatcgac gcccgcttcc cgggctgctg cccggggtgg tccggtaccg aggcggagat
     6421 ccaggcgagc agcagcacgg agaccagggc caccagaccg aaggtcagcc gccagccgaa
     6481 gaccttgccc aggaaggtgc ccacggggat gcccagggag agtgccagcg ggataccggc
     6541 catggtgatc gcgatggccc ggcccgccag gtgcgggggt gccagccggc gcgcgtatcc
     6601 gacgagttcg gcccacacca cggccgcggc cacaccggcg gccagtcgga agaccatcgt
     6661 cagggcgtag ttggaggaca tggcggtgac gacgttggcg acggcgaacg tcgtgaccgc
     6721 gatcagcagc agcctcttgc gccgccaggt cgccgtcgcc atggacatgg ggatcgccga
     6781 gagtcccgtg gcgatcgcgt agatcgtcag tgtctggccg gcggcggact cgctgacgga
     6841 gaggtcgcgg gccatctccg gcaggacgcc ggcgggcagg gcctcggtga ggatgcctat
     6901 gaaggccgcc gtgcacaggg ccagcagcgg cgacatgggc agcttgccgc cctgggctga
     6961 cggtgtgtca gtctgcgatt ctgtatggga cgttgtcatg cctgttatcc ttcaaccctc
     7021 acatgtatgt gaatgtcaag tcgctatggg gtgagtcata tgcgcatcgg ggaactggcc
     7081 gaacgcaccg gaacaccgcg ccggatgctg cgctactacg aggagcaggg gctgctcgta
     7141 ccggaccgct ctcccaacgg ctaccgggag tactgcgagc ggagcgtgga ccgggtcctc
     7201 cagatcaggg ggctgctcga ctccgggctg ccgacccgca tcatcaagca ggtcctgccc
     7261 tgcctgaagc tgccccgggc gatccacgtc acggacgccg cacccgagac gatcgcgacg
     7321 ctggagcgcg agcgggaccg gatgacccgg cgtatcgagt gcctggtccg cagccgggac
     7381 gccatctccg agtacgtgga ggccgtgcgc cggaaccggc cgcggcccgc ggccgagccg
     7441 cccgtcgcgc ccgtcacgtc agccgcatca gccgcatcag ccacggacta cgcgctgccg
     7501 ctgtcggcct gaccgcactg gaccgtgttg gccagcacga caccgtggct ggtcacgtcg
     7561 atgaccatcc ggtcgccgtc ctcgatgcgg aacccgtcgt ggtacgtggc cttgtccgcg
     7621 ccgagcagca ggtagttgac cagtcccggc cgacgcagcg cggggtacga gaacaggtag
     7681 tcggtcatct cgtcgacccg gtggtagagg gagtcggcgc cgcaggagaa ggggccctcc
     7741 caggcccggg cgccttcccg ctcgatgacg accctgccgg tcacctgccg cggcggcggg
     7801 tccgggaaca gccacggcgt gagggaggtc tcgcagagtt tggcgtaagg cgtccaggcc
     7861 cacgggttct tcaggtgcag accgatgtcg ttgaggtcgt tgccgaaggt gtagccggcg
     7921 tagtgcggga cgccctggtc gtcgttgacg tacacgagcg ccacctccgg ctcctccagc
     7981 agccagatcg ggtcggccgg ggtgatcagc ggctcgtccg gcatccgcag ccacgagccg
     8041 aagcccttga tgtagtagtt cggcggggtg aactcctcgt cgggctccgg gtctcggtcg
     8101 aacttcgagc ggtgggtgcc catgaagccg ttgatcaggg cgttgttgga gcccgtgggc
     8161 agcaggggcg gcaggaagcg cagctccggg tcgccgaggt cggcctcgac ggtctcggtc
     8221 gcctcggtca cggctgcgcg caacgcctcg gggcccccgc cgccgacgag ggccgcgcgc
     8281 agctgcccgt cggtcacgcg gtgcagcgtg tgcggctcgc cggcggcggg tatgccgagg
     8341 cccgcgtacc ggacgccccg gtactcgcat tcgaagacgg tggacatggc ggtgagcatc
     8401 tcctcggatc ggggatcgga gtcgggatcg gctgtcgggg atcggggatc aggggtcggg
     8461 gatcggggat cagggatcag ggatcgggga tcagggatca gggatcaggg gtcgggggat
     8521 tcagcgcgtc aggtcgtcca ggacctcggc gacacggtcc agggaccgcc ggatccaggg
     8581 cagtcggagg gggtcctcgg ccgacagggc ttcggtgcgt tcggcgtcgg tctcgccgta
     8641 gagccggctg gtggcggccc ggacccgcag gggccgccgg gactcgccga aggcgctgcc
     8701 gggcagcagg cccacgccgt ggcgccgtgc gagcagagcg gcgagcgcgt cgccgtcgtg
     8761 cactccgtgc gcggcgccga gatggtcccg caacggctcg aagtcggggt agaggtagca
     8821 ggtcgcccgt accggagcca ggacggcacc ggcggcggtg aaccggtcgg ccaccgcgcg
     8881 gaccacggtc ccgtgcagcc tccgggcggt ggcgacccac tcgaccacct cggggggttc
     8941 ggtgagggcg tacgccgccg cggcctgcac gggggcggcg gtactcgacc agatctggct
     9001 ggcgatcgcg agcagcctgc cgcggacctc gcgcccggcc ggcccgtccg ggagccgggc
     9061 cactcccgtc cgccagccgc ccagtgccag gttcttggtc aggccggtgg tgaccacggt
     9121 ccgttcgggt gcgaagacgg ccggggagac cgcccggtcc gccgggtcga agaccagatc
     9181 gcagtagatc tcgtcggaga tgatgatcag atccagttcc cgggccgcct cgccgaggcg
     9241 ctggacggtg gcggggtccg cgatggtgcc ggtcgggttg tcgggcaggg tgaccaccac
     9301 acaccgcggg tcgagacctt cggcgcgtgc ctgggccacc ctcgcgcgca gcgcctccgg
     9361 atcgggtacg ccgccctggc ccggcagggt ggggaccgcg atcggccgcc tcccggccag
     9421 cctggcctgc gccgcgtagc tgacccagct cggtacgggc atcacgacat ccccgccgac
     9481 cgccggcagc agcgcgaaga gcagcggttt gctgcccggc ccggagacga ccaggtccgg
     9541 gtcggtgtcc aggccccggc gcgcccagta cccggcggcg gcagcgcgca gttcccggct
     9601 tcccgcgacc ggaccgtagg cgttgcggcc cgatgcctcg gcgagtcgtt cccgcagtac
     9661 ggtcaggacc ggcaggccga tctcaccact ggccagggac aggacctctt ccccggcacg
     9721 ccggcgacgg gccagggcct cgtcggcggc cagggtggcc gacatggcca ccggcacggg
     9781 ttcggacatg gttctcctcc gctgagtccg gccgggacgt ggccgggggt gtgggaagac
     9841 ggggcgggcg gaactgccgg aacgggaacg ggaacgggaa cgcgaacgcg aacgcgaacg
     9901 agtaggggaa cgggaacggg cacgggaaca agaaggggaa ggggaaggga aacgggaagg
     9961 ggaccgcgag cggcaacggc aacgcgagcg gcgcatcgga tcagccgccg gagaagcgtt
    10021 cccggagttc gaccttgcgg accttgcccg tcagggtctt gggcagcacg tcgaccactt
    10081 ccaggcgctc cgggaagaag cgcgggtcct gaccgtggtc gcgcagatgg tcccggatct
    10141 ccggcagggt gggccgggcg ccgccccggg gaacggcgac cgccaggatc gggtcgtcca
    10201 cctgcccggt ggggccgagg agggccgctt cggccactcc cgggtgccgg gagaggatcg
    10261 cctccagttc ggccatcgga acgacgattc cgtctcgcag gatcgtgtcc ctggaccgcc
    10321 ccaggatgcg gataccgccc cggccgtcct cgcgcgccac gtccccggtg tcgaaccagc
    10381 cgtccgaggt cagctcggag tcgaaggcgt cctgttgctt gtagtagccg agtgcctgcg
    10441 acgcgccccg cacccgcagc cggcccacgg gggcgcgcct gccggcgtcg tggcactggt
    10501 cgatccggat ctccatggag tcgatcggcc gaccgtggct gtgcgcggcc cagtcctggt
    10561 tgtagtcgag ccgggtgatg gtgaccgggc cgaactccga catgccccac accgagtacg
    10621 tgcgggcgcc gaaggtgtcg cgcaactcgt cgaccagttc ctgaagcacc ggcgcagcgc
    10681 cggtgatggt gtgccgcagg ctggagacgt cgcggggctc ggtctgctgg gcggccgcga
    10741 cgccggacag cgtgggcggt ggcccgtaga ggagcgtggc accgtaccgc tccaccaggt
    10801 ccagcagccc gacgtggtcc gggccgtcct ggaaggcgat ggtcccgccg agcatcactc
    10861 cggcgaggac gccctggccg aagcccgagt agtgcacgag cggggtggtg accaccacca
    10921 ccatgtcgtc gcggagcagg aaggtgtcgg catagccacg caccccggag tgcacggtgt
    10981 tctgactgtg caccacgccc ttggagaagc ccgtggtgcc ggaggtgaac agcaccacga
    11041 aaggctcgtc cggccgcagg gcccggccct ccagatcgcc cgtgcgctgc ttctcccagt
    11101 gcgccgagac gaagtggtcg tggaagtcca ccgcgccctc gggggcgtgg ccgtccacca
    11161 ccaccacgtg ttccagggga agttcgtggc gcagggcgtt gatggtttcg gcgagcggat
    11221 agccgtccca ctccgcgacg gtgacgcaca cccgggcctc ggtgagcgcg aggcggtggt
    11281 gcagttcctc ctcccggcag accggggcga tggggcagat gaccgcgccg accgccgtgc
    11341 aggcgaacat cagcggcacc atctcccacc ggttgggcag ttggaccgcc acgacgtcgc
    11401 cccgctcgac accgagttcg agcagcgcgc cggcgaaccg gtccgtcagc cgcgccagtt
    11461 cggcgtagtc gagcgtgtcg gtacgggcct cgcccagccg gcggccggcg atggcgagct
    11521 tgcggggccg ttcgcgggcc tgccggcgca ggtcgtcgag gaaggtctcg tcgcgccacc
    11581 agccgcgccg ccggtactcc gccatccggt cggcggtcgg cgcggagacc ggggtcctga
    11641 cggtcgtggc cgtcatcaca gctccttccg gcggaccgcg atcagctcgg ggagcgggtc
    11701 gcccgccgcg gacgcggcga tctccagcag gtcccgggtg ttgcggcgca cccggtcggc
    11761 cacccagtcg aagacccact gcctgcgcgc gtcggccgcg agcccgaagg ggacgacccg
    11821 ggtgacggcc agagcggccg ccccggcccc gccgatgttg gcgatcacgc cgggtaccag
    11881 ggcggcgccc gaggcagcgg ccttctccct ggcctccgcg ctggaggcga ggttggcgcc
    11941 ctccacgacc aggcgggccc gcagccggtg cgtgttgtcg gcgttgagcg cgtgcttctg
    12001 cgccgcgagg atcagcacgt cggcgtcgac gtccagccag gcgtccggct cgttcgccac
    12061 cgtgacgtgc tgcggaagcc gggaacggtc gatccggccg tacgcgtcgg tgatggccag
    12121 caggtcgccc acggggagcc ggtcggcgct gacggtgccc tcgatgtccg cgacacccgc
    12181 gatcacatgg ccgcggtcct ccaggaaccg cgcgaccgcg cggcccaccg ccccgaagcc
    12241 ctgcaccacg acccgtgccg gttccgtgcg gcggctcgcc tccagggcgg tgaccgcggc
    12301 cacgccgacg ccgtgcccgg tggcgtcgat cagcggctcg tagtaggtgc gccagtcgat
    12361 cggcatgtcg ggggcgccga gccggtggcg cgggtcgtag ccggcctcgt cgaagaacac
    12421 ggcgcggtcg gcggcggtga cgcccatgtc gatgccgagg tggatgccgc cgtgcagcag
    12481 cggcttgacg gtgcggccga aggtccggaa ggtctcctcg cggtcgcctc cgtcggagac
    12541 gatgccgccc ttggcgccgc cgatgcgcag tcccgccagc gtgaacttgt cggtcatgtc
    12601 gcgggccaga ccgcgcactt ctccctcggt caccccgggg gtcatccgca cgccgcccat
    12661 cgccaggccg tccaccagcg tgtcgacgac gacccagccc ttcaggctgc cgccgctgcc
    12721 gttgaggtgc acggtgaacg cgggctgctg cggatcgtcc acgttgctca ttgccaagtc
    12781 ctccagttcg tcgctgagtc agagaggtac cggggcccac gtccgggatc gcgggcgtcc
    12841 gcgtcgggga tcgcgggcgt ccgcgcccgg gacggggcga ggtggggcgg aacggggccg
    12901 ggcgggccgg gcgggccggg tggctcactc gtagagccgc gcgaagccgc gcaggatctc
    12961 caggccgtcg cctcggaact ccaggtgcgc ctgggcgccg tggatccgcc cgtcgtcgga
    13021 gcgcaggaac tccacgggcg cgtgtgcgga gcgcccgatg gagcggaagc cctccggggc
    13081 ctcccggagg tagagggtgt ggcggtggaa gacggtcacc gtgggcttga cgtaggtgaa
    13141 cagcggctcg tccggctcca cctgggcctc gtggccgccg acccgctgcg gcccctcggc
    13201 cagccggccg ccggccgcca ccgcgatgag ctgcatgccg ccgcagatgc ccaggacggg
    13261 gacgtcggcg cccatgacca ggtcgacgag gggccggtag aagcccgtgt cgtaggcccg
    13321 taccttggtg ccgctcagca cgatcgcctg atagcggccg ccgaggccgg tgggcacgga
    13381 gttcacgttc accgcgtcgg tctccgaccc caggtgctcg aagcgggccc ggagctgctt
    13441 gagggacagg gtgccgttgt cgacgacgag cactcgggat ttcgccatgc ggggctcctc
    13501 agctacgggt gatgacggtg ccggtgcggc cggcgagcag ctcggtgacg ggcgcactgc
    13561 cgatgacgac ccggtccact ccgccgtcca gggcctcccc cgcggcgcgc agcttcttgc
    13621 gcatgccgcc ggtggcgccc ctgtcgcgga acccggctgc ggcccgcgcg ctgatcgcgg
    13681 cgaccggctc gccgtcgacc agcagatggg cgacgtcggt gacgaggacc agatcgccgg
    13741 cgccggtcgc ggcggccagg gcggcggccg cccggtcggc gtcggtgttc acctcctggc
    13801 cgccgtcgtt gcgggccagc ggggtgacca ggtgggcatg gccgggctgg aggttcttca
    13861 gcccggtggg gtccacgccg gtgatcgggc cgaccaggtt ctccagctcg accagttgct
    13921 tgtcgcgcca ccaccagcgc tcgccctcac ccgcggcgac caggccgtcg ctgccgagga
    13981 cccgttccgc ggcgatgccc cgccgctcca gccggccgag gatgtcctcg ctcatgcgcg
    14041 cgctgacggt cttgatgtcc gcgatgacct ccggcgtggt ccaccggctc tggttgccgt
    14101 accggtcgcg caggaccgcc gagggatcgc ggtagcgcgg gtccagctcc ctcagcggcc
    14161 tggaccagcc gtgcaccagg acaagcggcc gctcccgccc gtgccgggcc aggtcgtccc
    14221 accaggtgtc ggccagatcg tccaggcagc tgccgcccag cttcaccacg gtggggaccc
    14281 ggccggggtg cgtgccgctc atgccggcat caccggctgc atcgtcagcc ccgtctcctc
    14341 gggcagtccg aaccggatgt tcagggcctg cacggcctgg ccggccgctc ccttgacgag
    14401 gttgtccagg gcggcgagca cgacgatgcg ctcgccgtcc tcgtcgtgca tgaccgtcac
    14461 gtcgcagtag ttggagccca gaacggcctg ggggtcgggc accgggatga gcgtctcggt
    14521 gttccgccgg acccgcacga accggtggtc cttgtagaag cgcagatagg cgcgctgcaa
    14581 ctcgcgctgg tcgacgctct cgtcggtgaa gacgtacgag ctggtgagca gaccgcggac
    14641 gtgggagacg ccgtaggcgg acatcgacag cctgcccacg ccgccccgct tccctcgctc
    14701 caggaagtcg ccgacctcgg ccgcgtgccg gtggcccacc ggcgcgtacg gtgcgatggc
    14761 gccgttgcgc agcgggtgca ggtcggcggt gcgcaggtgc aggccgccgc cgctggagcc
    14821 gctcttgccg tcgaccacca cggtcttcag gttcaggccc agccccaggg tgagcggggc
    14881 gagcgccagg gtcatggacg tggcgtagca gccgggcagc gagatcagcg cggcgtccgc
    14941 catctggtcg ccgaccagtt ccggtacgcc gtacacgaac cggtccgcga ggtcggtgcg
    15001 ccgcttcacg tcggggtacc agcggtcgtg gagttcgggg gtgcggatgc ggaaggcgcc
    15061 gctgaggtcg agaacggcgg ggacccggtc cgcgagcagc gcggccagct cggccgacac
    15121 gggtgccggg gtcgccagca ggacggcgtc gacctgaccg gcgatctcct cggtgaccgg
    15181 ctggaccgtg aggccgaggt cgagccgtag gcccgggtgg agttcggccg ggcgcctgcc
    15241 gatgttcgag gagccgccga ggaaggtcag ctccaggtcg ggatgctggg tgatcagcct
    15301 gatgagttcg ccgccggcca gcccggaagc tccgacgact cctacccggg tcacgtgagt
    15361 gtctcctgta gatggcgggc gacggcccgc gggatgtccg ccccggtcgc cgcggcgatc
    15421 gccttgaagg cgggggcgtg gttgacttcg ttgacgacgt ggccgccggg cacctggaac
    15481 aggtcgatgc cgtagatgcc cgggccgagc gcgtccacca ccccgtcgac gatcttggtg
    15541 atggcggggt cgtggtccag ggcccggctc cggttgccca gcgccgcgtt gctgcgccag
    15601 tcgccgccgg cgctcgcgaa ctcggcggtg gccaccggct cgcggcccac gaccaggcac
    15661 cggacggagg tgccgccgtc gaggtaaggc tccaccagcg aggcctgttc gaagccgtgt
    15721 ccgaggtcct cgacatagtc gtagacggac tgggccgtgt cggtgtcacg gatcagcgtg
    15781 accctcttgc ccataccgcc gaagacgggc ttgagcacga cgggcggcgg aacgtccttc
    15841 agggcctgct cgaaatccct gcgggacagc accagccgga agtccccggc cggaacgccg
    15901 gcccggtgca gtacggcccg cagctccagc ttgttctcac aggcccggat ggccgaggcg
    15961 gtgttgatgg tgcggatgcc ggacgcctcg gccagtgtgg cgatcaggcc gccgcgggtg
    16021 tagctgcggc tgcggacgag gacggcgtcg tacccggtca gggacggcgc gtcctggtgc
    16081 ccgaggcaca gggactcgtc gttgacccag tcgacgacga gtccggcctc gggtgcggcc
    16141 tcgatcagcc ggcgttcctc ccagccgatc cggtccgcga cgatggcgac ggtggcgctc
    16201 atgggtgccc tctcctccgc gggtcgtccc tcactggccc cagtcacgca gctgcacctc
    16261 gaccatctgc agggtgacct tgccgttcgt cacgtcctcc acgcggaggg tgagcatgca
    16321 ctcggggcag gacagggtct cgcccgggac catcggggga acggtcagat cggtctcgca
    16381 ctcggggcag gatccggcca gggtggcggt ggtcatgaac gactccggtg gtgtgaggag
    16441 atggagggca cgggcacggg catggggtgg gcaggggcag ggggtgggca cggacagggg
    16501 cagggggcgg gtcatgcggc ctggaagtcg atggccgcct tgcggatggc gtcccggtcg
    16561 agcagcgggc cgccgtcgcg ctcctggcgc tcggtcagcc acgcggtgaa ggcctcgacg
    16621 tcgacgagca caccggattc tcggagggcc catgtgacga gggcgggagt gagtcgggta
    16681 cgtacccgca actcgcgctg gttgcccacc agttcggccg gcagcgtctc gtacgcctcc
    16741 gggtgggtga gctggcccgg cagctcgtac gcgaaggcgt gcggtgtggt cggtccggac
    16801 tggaaggcct cgccgagccc ggcgcctccg agggcgatcc gggacagctc ggtcagcccg
    16861 ctcaggtcga agcgggtgtc gccgtggacg acacgcagtg cggtgagcag ctcggccagg
    16921 ggggcgttgc cgccgcgctc cccgatgccg ccgaccgtcg cggagatcca ctgcgccccg
    16981 gcccggacgg cggcgagcga gttggcgacg gccatgccca gcatgttgtg ggagtggatc
    17041 tcgatctcgg agccttcgat cgcggtgagg cccgcgatca cccgctccat ctgccagggc
    17101 gagaggcagg cgacggtctc cgccagccgg aaccggtcgg cgccggcctc gaaacccgcg
    17161 gtgacgtagg ggacgagccg ctcccggggg gtgcgggcgc cgtcctcgcc gctgaaggtg
    17221 acgtgaaagc cgcgctcctt ggcctgggtg atcgcggaac ccgccagtgc gtgcaggaac
    17281 ctggcgctcg gcgagcccag tttgagcttc gcgtgctgct ccgaggtggg gatggagtac
    17341 atgatgtgcc gcacgccgag gcgctcggcc tcggcgaggg ccgtggcgac ctgccgtcgg
    17401 tcgcgcacga ccaccagggt catgctgcgc tccggaccga cggcctcgtg ggtggcgagg
    17461 atcagatcgg cgtccttgga gttcgggccg gagaccatcc cgacctcgac cagctcgaca
    17521 ccggtccgga ccagcaggcg ggccatggcc gcggcgtccc cgggacggaa ctcgacgccc
    17581 gccatgtggg cggagtcccg cagtgtcgcg tccgacagac gggggcgccc ctgcgggaga
    17641 gcgccctctg gctctgtacc gtccattgcg tttcctccct ttccgctcct cgaatggagg
    17701 agatgcggtg cggatcggtg aacatgttgc gcggattgcg tgtgagggag caaggaatcc
    17761 tgtgtcagga ctgtgtcaag cactgtgagg cactgttaag ccgagaaagc agtgtgaact
    17821 ccccgcgccc cgcgggaaga ttgcaagaaa tctctggcca gaatgttcgg gaccacagcg
    17881 caattggcca tgatggccct acctcattga tccgcaccgc cctattcatg cggctctgga
    17941 cgatccagtg acaggagagg aaggaatccg atgctgtttc cgtattcccc cggcgaacgc
    18001 ggcaccgagg gggccctggc cgaacagacc cgggaactgg ccgaccgcgt cgtacggccc
    18061 accgcggccg accgcgaccg ggaccgcagc tgggacccgg ccctgttcgc ggaactggcc
    18121 gacgcgaggc ccgggctcac cggacccctg gtaccgggcc ggctgggcgg tggtggcctg
    18181 accgccgccc agacctgtgc cgtgctgcag ggcctcggcg agggtgcccg cgatccgggc
    18241 ctggccctcg cggcggcggt gcacgcggcc ctcgtcaccg tgccgctgcg cgccttcggc
    18301 accgcagcgc agcagcggcg ccggctgccg cggatggcct ccggcgagtg ggtgggtgcc
    18361 ctgtcgctgc gtcagacgca gggcgccgcc ctcgcccccg cggtcaccgc ccggcccgcg
    18421 cccgacggct gggtgctgga cggcgccctc gacctggtcg tcggtgcgcc cctcgcccgg
    18481 cacttcctga tcgtcgccgc gcatccggac ggcagtggcc gtaccgcgtt cctggtggac
    18541 cgcggtacgg ccgggctgcg cgtcgaggac gttcggccgg aggccctgcg gacctgcccg
    18601 tggggcggtc tggcgctgga cggctgtcac gtcccgcacg acgccgtgct cggcagcccc
    18661 cacggtgccg cgaccgaggt cgagcccctg ctggcggtgc tgagctgggt gttctccagc
    18721 gctccctggc tcggcgtgat gcgggcgctg acccgggacg cggtggagcg ggtccgcggg
    18781 gaccgcctct tcgaccggcc cctgtcccac ttccagtccg cccgcctcac cctcgccgac
    18841 atggccatcc agtgcgaact ggccgccggg ctgctctacc gggccgccgg ccagttcgac
    18901 ggcggcgggc ggccgtcgca gcgggacgcg gccgcggccc ggctcttcgt ggccggtgcg
    18961 gcccggaccg tggtcgaggc ggcggcgggc ctgaccgggc cggccgacgg caccggggac
    19021 ggactgatcg aacgggccca ccgcgacgcg ctgttcttcg gcacggtcgg cggcggcgcg
    19081 gaggtgctgc gcccggtcat cgcggcctgc gagctgggac tgggctgacg accgaccgcc
    19141 cggacggcgc cgggacccgg caccggaccc ggcaccggac acgcaaccga gcacggctcg
    19201 gaacaggaca ccgaacagga caccgcgaac acgagaacac ccgaacacga agggagcagt
    19261 caccgacgtg aacgtccacc gacacggcac cgacgccgca ccgaccttcc ccggcacggc
    19321 cgcacgggcc gccgagaccg acctgacagc ccgcataccg gcgcagaact ggaaggaggt
    19381 cgtcgacagc ggctatctgc ggctcttcca tccaccgacg gtcggcggca ccggcgccga
    19441 cggcgccgcc caggtggcgg ccatggagtc gctggcccgg gcctgcccca gcacctactg
    19501 gtccgccacc gtctccgcgc tgctgtgcgc caacctgatc tccacctacg gcgacctccg
    19561 ggtccacggg cagctgctgg aaggactgct ctccggccgt ctgctggccg ccttcgcggt
    19621 ggtggagacg accgcgggca gcgacgcggg cacctatacg acgaccgtgc gtccggccgg
    19681 ggagccggac ggcggcttcg tgatcgacgg ggagaagtcc cggatcacga acgccccgga
    19741 cgcggacgtc gcggtcgctc tggcccggcg cgagaaggcc gccggcgacg acggccccga
    19801 ctggtgcctc gcgttcgtgg acctgcggca gcccggagtg cgccgctacg acatcccgcg
    19861 catggggctg cgcggcatgc cgtggggcgg cctggtcttc tccgatgccc gggtctcggc
    19921 gcaggacgtg gtgccggtcc cgctggacga gctgtccgag ggcatgacct ggggttggct
    19981 gctggtctcg gtggcagccg tcgccgtcgc cgagtcggcg ctgaccgcct cggtacggca
    20041 tgccggcgag cgcgtctcct tcggtcggcc gctggcccac atggaaggcg tccaggcgca
    20101 gatcgcccag tcacgggcgc agatcgacgc cgcccgtctg ctcgcccggc gcgcggccgg
    20161 ggaacgggcc gccggacggt cggccaggag cctgatcgcc atgctcaaga tctacgccac
    20221 cgagatggcc gtcgacgtca ccgcgcgtgc cgtgcagatc cacggggcga gcggcgtcac
    20281 gcaggggcac gaggtggagc gcctctaccg ggacgcccag atgaacgtga tcggcgcctt
    20341 cgcctcgaac cggctgcgcg agcaggtcgc cgaaggcatg ggcctgggcc cggcggtcta
    20401 cgagcccttc gactggctca ggccgagcgg cctcggcgac gccgcggtgg gcctggacgc
    20461 ctccgaccgg tccgcagacg cctccggccg gtccgcagag gccgcctgac tgagaccccg
    20521 agacccctgg accgccggcg gccggaatgc gggccgccgg cggtccgagg tgtttcccgt
    20581 accggaattc accgcgttcg caccgtgggg agttgtcgcc ggtcgacggc tacccccgcc
    20641 ccatccggta gccgacaccg cggaccgtga taatccagcc gtgagaaccc agcttggctc
    20701 gtaaactccg cacatgggtg tcgatcgtgc ggctggaatc cccccaccgg gaaccccaga
    20761 cacgggccat cagctccttg cgggatacga cggattccga gttggcggcc agcatgtgca
    20821 gcaactcgaa ttccttggcc gtgacgtcca ccggttcgcc gtgaagccgg atctcccgcg
    20881 ttgcgccgtc gatccgcagc ggaccgacgg acaggaccgg ttcccgttcc ggtcgcgggt
    20941 agacccgacg cagtaccgcc tcgatccggg ccatgatctc gcgcagaccg cacgagacga
    21001 cgacgcagtc gtccgctccc gcctgaaggg cgaggacgcg gtccagctcg ttgtcgcgcg
    21061 cggtgagaga cacgatcggc ttgtcgtcga cctcacggat cagccggcag acctccaggc
    21121 cgtcgatatc ggggagatcg aggtccagaa ggacgagatc ggcctgcgta tgggcgctca
    21181 gggccttcgc ccccgactcg accctgctgg cgacgtagcc ctggcggcgt agctcccgca
    21241 cccgttcctc ggccagttcg gcactgtcct cgacgaccag cacgcggaag cggccggttt
    21301 cggccaccgt tcggcccggc agggtgccgc cgctcctcga cctccgcacg taccccgaac
    21361 gagccggttg cgccgcgtgc actcccaccg ctccccctct cgtgtacttc cgcacttcca
    21421 aaagaacaca cgtcctgtta tttgtacagc caggacctac caacaaatgc cagcataact
    21481 agacgaattg gacagataaa gttgctcggc atactcggca tcagggccag atcggaccta
    21541 aagcccaaaa caagtggcta gaaaaccgaa cgcaagtggg agtaatgtcc ctcgcagggc
    21601 gaccgcacag ggctcaaacg gccggctttc gccagccgca tcaccatggt cgacccgcga
    21661 gcgacatgcg acatcgctcg gacggcatca tatgctgggg gttgcatatg cgaatcaagt
    21721 gtggcttgca cggagaagga acccgttccg ccccggcaaa gcgccggggc tgcgcgcgga
    21781 cgaaccgcac acagccccgg cagcggcggg ggaagggccc gtcactccac cgcggaggtc
    21841 cggctctgct ccttgagcaa ccgctccgca cggtagggcg aggagtcgat ccgggcgagc
    21901 acggtcggcg tgacgacgtt cggcagcacc agctggtaca gcaccgagat ctcctcggcc
    21961 aggtccagat cctcgctcat cgcctcgctg accagctgga cgccggtcca tgatccgacg
    22021 accgtgcggg agaccacggc ggggtcggcg tgcgggagca gttcgccacg ctgcttcgcc
    22081 tcggtgagga agccctcccc gaccgccacc cagtccggcc accgcgtgcc gaacaacctg
    22141 cgggccttgg ggtcgacgga caggcggatg gcggcgtgca gtatcggctc ccgcggcacc
    22201 cggtaggcca gcagcaggcc cagatccacc cactcctgca ccttgaacgc ctgctcccgc
    22261 aggccctcgc gggtcacggc ctcgtcgagc acggcacggg cgatgtcctc cttcgaggcg
    22321 aagtggaagt acagggcccc acgcgtgagg cccgtccgtt caaccagcgc ggcgatggtc
    22381 gcggcgtcat acccgacctc gttgaaaagg ctcgccatcg actccaagat ttgattgcga
    22441 gtgcgaattg cacgatcttg cttcgccacg ccgcacctcc gtccttcatc caggcgtgcc
    22501 atcggttccg gcacgcaagc cccgtcgaaa taaccggacc ttcggtacgt tatcaaggcg
    22561 caccgcgggt tccggcagca gtgtccgcaa ccttgcgctc taggaggggt ccatgaccgg
    22621 gtccacggat gcgtcagtca gcccgcttcc ccgtctccac acgggctgga gagagaagat
    22681 tggtgagtac acgcatctta cccacggtgc cacgctgctg gtcggagact ggcggaaaca
    22741 aggccctgac acccacctca tatccgttcg ctggccctcc aacaacacga ccggcggcgc
    22801 cgatccccgg ctgctggcac agaccgtccg gcagtgcgga ctcctcgtcg cccacgccgc
    22861 gtacggggtc cccaccggcc accacaccct gctgcactcc ctcaacatca ccacggaacc
    22921 gggcttccgc gccggcgagg gggcctcgtt cgaagtccgt ctgacggtca cccgggcgga
    22981 gagacgttcc tccacgttga gcatggtgct ccacatccgc agccgggacc gcaccgtggc
    23041 catcgccgac accgtcttcg cctgggtgtc tcccgcggcg taccggcgga tgcgcggtcg
    23101 gcgcctgcat gtcgactggg ccggctggcc cgtaccggac cccgccgccc cgcacctggt
    23161 cggcagactg caccacggcg acgtcctcct ggcggacggc gggagccgcg accggtggcg
    23221 gctgcgcaac gacgtctcca acatcctgct cttcgaccat ccggtcgacc atgtgcccgg
    23281 cctggtcctg ctggaggcgg cacagcaggc ggcgcacgcc ctcacctacc cggaccccgt
    23341 ggagttcacc gacgtgtcca tcgagttcgc ccggtacgtc gagttcgacg agccctgctg
    23401 gctcacggtc gaaccgctga ccacgctcct gcccgagtgg tcctcgctcc ggatcgccgg
    23461 ccggcagggc gagcgagacg tcttccgggc ccggctgaag gggctgcggc ccgcgtcgtg
    23521 aggatcggcc cttcggcccc ggcggcggga cggcgccccg cgggacgagt agtgccgccc
    23581 gccaccgcgt tccccgtgag gcacccgggg aagcggcggc gggcggcggc ggcccgccga
    23641 cctgccggtc gcgggggatc agtggttgac gaagccgccg tccaccggca gcacggcgcc
    23701 ggtcagaaac ggacagcggt cgctgagcag ccacgccacg gcggccgcga tctcctcggg
    23761 ttccgcggtc cggccctgcg gcgtcacgga gtgcgccacc tcctccagcc cggggttgcg
    23821 ggtgaaccag tcgacggtga tctcactgcg ggtggtgccc ggtgccaccg cgttcaccct
    23881 gatgccctgc ttcgcgtact cgtccgccgc cgcccgggtg aggcccacga cggcgtgctt
    23941 ggacgcgatg tacggtgcgg cggccggaat ggccacgagg ccgcccacac tgctgttgtt
    24001 cacgatcgca ccaccgccgc gcggcagcat ggcggctatc tcgtggcgca ggcagttcca
    24061 gacgccccgc acgttgacgt ccatgatggc gttgtagacc tcgtccggca tcagatgcag
    24121 cggagtgcgg tcgccgccga cccccgcgtt gttgaaggcg gcgtccagcc ttccgtacgt
    24181 ggtcaccgcg aagtcgacca cccgggcggc gtccgcggac acggtcacgt ctcccaccgc
    24241 gtaggccgcc tcacggcccc cggcccgcag ttcgcccacc accgcggcca accgctcctc
    24301 ccgccgggcg gccagaacca cggccgcacc ctcccggctg aacaccctcg cggccgcagc
    24361 accgataccg ctgctcgctc cggtgatcaa aaccactttg tccgtaagaa gttcgctcat
    24421 gagcgcattg ttccgatacc ggcacggcaa gccctggaag cctcctcgag tccccgggtt
    24481 gcggctctgc cgggtacccg gcagagccgc aacccgggga ctcggccggt ggcgaagggc
    24541 gcgccccggc gcggccgtcc ggtcggacga gcaggggacg ttccgggagc cggatcccct
    24601 ccgggagcgt gtcggagtct cccgccgggc accgcggtgg accgctcacg gcggcggtgt
    24661 tcgcggacgg atgcccgccc acgaccgggc ggccgggcag ccgggcagcc gggcagccgc
    24721 gacgacggag cggggtgtcc gcgcggcgaa cgcgcggaca ccccgctccc ggtgcggtgc
    24781 tccgtactac ctgaccgaag gaccgaccct gaccgtgatc gtctggccct tcttcggctc
    24841 cttgacgatc gagatcctgg tgttggtgtc cgggacctgg acaccggcgg tcgggttctc
    24901 ctcgaaccag tagacgccct tgcggtcgtc gaagaccgag ttgcccctgt gcgccgcgat
    24961 acgcgtgggc acatccgcct tgtgcagggt gagggcgtcc gagcggaacc tgctgaaggt
    25021 cgagtcgaac gactggatgc ggttgcgcat cagcgtgccg tcggcccact tgagggcccc
    25081 ggggttggcg tcgaccggaa ggatcaggcc cttgcccggg tgctggctgg tgttgttgtc
    25141 cttctgcgag gtgtcccaca gccagatgag caggccgttc tggtacggga agtgctcgac
    25201 ccagccgtcc ttcggcgcct tgaagccgaa gttgtacggg ccgacctcga gggtctggtc
    25261 gtacgagacg tactgccggt tctcggcgat gtagtactgc tcgtactcgt ccgtgaagga
    25321 ctcgccgatg cgggagaagc ccttggcggt ccagccgggc gcctcggtct cggcgtcgtc
    25381 gctgaagagc ggggcgccgt ccgcggtgac gacgatgccg tccgcggcga agcccttgcc
    25441 cgccacaccg ccgtccgtct ggtagcggaa gcggatgtcg accttctcgc ctgcgtacgc
    25501 gtcgagcggg tacacgagct tcctgtgcgt gtccgacggg ccggtcagcg ccggcttgtc
    25561 ggaggcgtcg cgggtgatcg ccgcaccgtc ggcggtgccg tccacggcgg tccagttggc
    25621 gccgccgtcc gtcgacacct cggtgtagag gtagtcgtag tcggcctcga tgtcccacca
    25681 cccggtgagc tccagcgacg cggtggactt gccggtgagg tcgagcgaac gggtcagggt
    25741 gttcctgagg tcgtcaccca tgtcgctcca ccactgcatc gagccctcgg cgggctcgac
    25801 gacgccggtg gtgaccttct tcttcggcag ctcgaccacg agggcctgcg ggttcctggt
    25861 gttgtactcc gccacgccga gcttgtgctt ggacgccgtc gccgccttgg ccttggtgta
    25921 gttgagccag ccgagctgca gcttgtccca ggcggtcatg tcaccgggca tgtcgccgat
    25981 ggagtcctcg ccggtgccga gccaggaacc ggacgacatc agggaccaga agccggtcga
    26041 gttctccccg ccgccggagg tgtcgtacag gtcgggcaga ccgaggtcgt ggccgtactc
    26101 gtgggcgaag acgcccaggc cgccgttctc cggctgcatg gtgtagtcgc cgacccagat
    26161 gccggtgtcg ccgatctggg tgccgccggc cctgttgtcc gccgggccgg tccggccggc
    26221 gtcggtgccg taggcgtacc agcggtgggc ccagagggcg ttcgggccct cggcgccgcc
    26281 gccggccgac tcgtcctcgc ccgcgtggac gatctggaag tggtcgatgt agccgtcggg
    26341 ctcgttgaag tcgccgtcgg cgtcgaagtc gtagcggtcc cactggtcgt actgcgccag
    26401 gtcggccttg atctgggcgt cggtgcggcc cttggccttc tggtccgcgg tccaggcggt
    26461 gaccccgtcg cggaccgcgt cccacacgtt gttgcagttg gactggccgc agtagttgga
    26521 gccgtaacgg gcctcgttcc agtcgacctt gacccagtcg gagacggtcc cctcgaccga
    26581 gtaccggccg gaggaggtgc gctcgtagta ggtcttcagc gagtgcttgg ggttcccctt
    26641 ctcgtcctcg ccctcgccga agtacaggtc ctggaagtgc tgccggtcgt agtccttctg
    26701 ccaggcggtc gagttgtcca ccgcgcggtc cggctgggcg atcctgttgt gcagcggacc
    26761 gggggtgccg ccgtacttct tgacgggcgg cttggggccg tcgccgtccg ggtcgtacat
    26821 cgtggtgtcg tcgaccttgt cgccgaactc caccaggatc gtgaagatct tgtcggtctt
    26881 ctcccggccc agctcgacgt acttcttgtc gtcgagcttc accaccttgg acgcgccgcg
    26941 ctgctgcacg gtcgcgtccc ctgatatgac ctgctcgagt gccgcctggc gctgccgcgc
    27001 ctgctgctcg ctgaacgggc cctcgaggtc gtggtccacg tggcccttgt gggcctcgtg
    27061 gtggtcggag ccgggcgccg ggtcgtggcg ctcgaccccg ggagccccgg agggcctgct
    27121 gtccgcctgg gccgtcgtga gcgccgcggc cgttgcccct gtcgtggcca gggccacgag
    27181 caccgcggac gctctgaacg cccttgtcct gcctgtcact tgaaggtgtc ctcccccgcg
    27241 cgccggcgta ccgcggtcca agggaatgtg gggtggatcc gctcgcggca gcgcgtcaca
    27301 agtgacagca ttcgaccgga gttgacggag aaaaaccaga ccttgacttg cacaggccaa
    27361 ttgcactatg cagtagcgcg tttccggata gcggacggcc ggccaccgcc acgagcccgc
    27421 agcacgcccg cagcgcagcc cgccacgagc ccgcagcggc gaccctcccg cgcacggccg
    27481 cccggtcaac aggtgcatgc gcccggccgg ttcccgagac atgtgactcg atgcgccccc
    27541 ggtgcaccgg caccgtgggt caggtcacgc ttaccaccgg ttcctctcgg gcatccaccc
    27601 acgtagggcc gccggacagt gcggcccgtc gcgacacacc accgacatcg atgctttcga
    27661 gggacggaaa ccgtcatgcc gcgtccgact gccgcacagc tcgcctacgg ttcggccacc
    27721 gtcgtcgtct cgaccgtcgc catgcttctg ctcttccgta cgacgacggc gctcggtgtg
    27781 gccgtcgtcg cggtcgccgc gctcgccctc ggactgctgg tcgccgtgac cgtaccggcg
    27841 ccgggcaggg cgaaggcggc acgcacggcc gatcgaagcc gtgcggccgc cttcgaggac
    27901 cgctccctac cggaatccgc ccgggtgccc gccgcccgcg gcgcggcccg gcacggggtc
    27961 gggcagcact cagcccgccg ttgacaccac caccgtcttg gcggccttgt cgtgcaggcc
    28021 ctgcttgtac ggcttgtcca ccaggatgaa gaccagcagc agcagcggcc acaggcaggg
    28081 gcagcagatc agctgcggca gccagagcac cacggcgcgg gtcagggacg atccggtgtc
    28141 gggcgtgctc ccgtcgttga gcatcgccac acgcatcttc atgagcttct tgcccagcgt
    28201 ccgtcccgac ttgcgcacca tcagggtgtc gtagccgacg aacgcgacga tcgcgatgac
    28261 ctggaacacc cacccgccgg tgttgccgtc cgccacccag tcaccgaaac cgtcgcccga
    28321 cgtgaccctg ttgtagatcc cgaacgggat gccgatgaac agcagcggga tggcgacgat
    28381 cagccagtcg atgacgcgcg cgaggatgcg cttggcggag tcggccatcg ggggcatccc
    28441 gtgcagcgga tcgccgcctc cgtaggggtc gccgccgtac gcgtgcggat cgtacggcgg
    28501 aggcggggcg ccgtagggcg a
//
