LOCUS       NZ_CP029254            16284 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Streptomyces spongiicola strain HNM0071 chromosome, complete genome.
ACCESSION   NZ_CP029254
VERSION     NZ_CP029254.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces spongiicola
  ORGANISM  Streptomyces spongiicola
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7180417)
  AUTHORS   Zhou,S. and Huang,X.
  TITLE     Complete genome sequence of the Type Strain of Streptomyces
            spongiicola HNM0071, the producer of staurosporine
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7180417)
  AUTHORS   Zhou,S. and Huang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2018) Institute of Tropical Agriculture and
            Forestry, Hainan University, No 58, Haikou, Hainan 570228, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: ABySS v. 2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 850.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003122365.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 01:04:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,008
            CDSs (total)                      :: 5,921
            Genes (coding)                    :: 5,739
            CDSs (with protein)               :: 5,739
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 182
            CDSs (without protein)            :: 182
            Pseudo Genes (ambiguous residues) :: 0 of 182
            Pseudo Genes (frameshifted)       :: 47 of 182
            Pseudo Genes (incomplete)         :: 161 of 182
            Pseudo Genes (internal stop)      :: 9 of 182
            Pseudo Genes (multiple problems)  :: 32 of 182
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:10:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 189290
            Orig. end                         :: 205574
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029254.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..16284
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="aminopolycarboxylic-acid"
                     /region_number="3"
                     /rules="(AesA and AesB and AesC)"
                     /tool="antismash"
     cand_cluster    1..16284
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AesA and AesB and AesC)"
                     /kind="single"
                     /product="aminopolycarboxylic-acid"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..16284
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:11284](-)"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..11284)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="1"
     misc_feature    complement(1603..1618)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.6"
                     /tool="antismash"
     gene            complement(1913..2719)
                     /locus_tag="DDQ41_RS00740"
                     /old_locus_tag="DDQ41_00740"
     CDS             complement(1913..2719)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890531.1"
                     /locus_tag="DDQ41_RS00740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00740"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_109292691.1"
                     /transl_table=11
                     /translation="MGRITTTRLSWSVKGHRLLDGIDMAAPDGKTVGLLGPNGSGKSTL
                     LRLLAGLRRPDTGTIRYDDTSLDDLGRRVRARRLAVVEQDVSAHHHVNVRQVVELGRTP
                     FRGRFDALTERDRRIVDAALERTEISDKQHRSWHTLSGGEKQRTQLARALAQEPREILL
                     DEPTNHLDIRHQLELLDLLTHLDVTCVVALHDLNLAARYCDHVVVLDRGQVAAGGSPEA
                     VLTPDLIESVYGVRVLVDREPATGTLRITYLGATADRTAATQPQGR"
     gene            complement(2719..3747)
                     /locus_tag="DDQ41_RS00745"
                     /old_locus_tag="DDQ41_00745"
     CDS             complement(2719..3747)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891384.1"
                     /locus_tag="DDQ41_RS00745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00745"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_109292692.1"
                     /transl_table=11
                     /translation="MGARRARTAALLLLAAAGLLVSVVTATLFGSADIQPLDVVSTILR
                     HIGLDSIAPTAPLPGLHDALIWESRFPRVLLAAAVGMALAVSGAILQAVTRNPLADPYL
                     LGVSSGASTGAVAVLLLGVGGSISLSTGAFAGGLVSFGVLLLLLGGGRVASPSRVVLTG
                     VLVSQFFAAVTSVILMVGGDADSTRGFTYWLLGTLAGARWEGAAVTVVIILIGVVAVQF
                     LAPALDAFTFGWDSAETLGVNVTAARVRLMVLTSVMTAAAVAASGAIGFIGLLVPHAVR
                     ILAGPTHRALLPLSAIVGAVFLIWVDVFARTAFAPHELPAGVITALLGAPAFALVLKRL
                     ES"
     gene            complement(3828..4841)
                     /locus_tag="DDQ41_RS00750"
                     /old_locus_tag="DDQ41_00750"
     CDS             complement(3828..4841)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948649.1"
                     /locus_tag="DDQ41_RS00750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00750"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_109292693.1"
                     /transl_table=11
                     /translation="MIIRTCTALAILAVAGCAADRSPDDGGQDAKSAKGAAAYPLTLEN
                     CGVDVTYKAAPEKVVTLNQTAAEILIHLGVGDRIIGSGYEIEKTPDAIAEQYGKIPQLS
                     AKGDTVKHEKLLEAQPDFVYSSFASFLTKEEAGDRKELHDLGVPTYLTEFDCSYHEAVA
                     DADFDMLFEEYRRLGKIMNVPEAGEKLAAAQKALVDKAVGEVEKRDEPLKVMWFYSTFE
                     GTPWAAGPGGLPQHISELVGVENIFADAKSKWAEVSWDEAAARNPDVIILADLTRGEPN
                     DTAEEKIELLKKDPLTSKLPAVKGDRFITIPGTHMDPGYGSASAVPALVDGLNKLG"
     misc_feature    complement(4827..4842)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.36"
                     /tool="antismash"
     misc_feature    4830..4845
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.92"
                     /tool="antismash"
     misc_feature    complement(4832..4845)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.72"
                     /tool="antismash"
     misc_feature    4832..4846
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.38"
                     /tool="antismash"
     misc_feature    complement(4833..4848)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.85"
                     /tool="antismash"
     misc_feature    4838..4852
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 20.65"
                     /tool="antismash"
     gene            complement(5001..5984)
                     /locus_tag="DDQ41_RS00755"
                     /old_locus_tag="DDQ41_00755"
     CDS             complement(5001..5984)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890529.1"
                     /locus_tag="DDQ41_RS00755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00755"
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="WP_109292694.1"
                     /sec_met_domain="AesC (E-value: 3.9e-139, bitscore: 461.9,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PALP (E-value: 5.7e-59, bitscore: 198.4,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTRISDLIGRTPLLELPVADGSATVVLKLEQYNPTGTAKIRMA
                     RSMVEEAEEAGLLTPGGWLVESTSGNTGLGLALIAAERGYKFTAVVDNHSSTDKLRGML
                     AYGADILNVAGDEEGLATAERDTVAERLAAEHGAYWTAQHRNQGNPNGYRPLARELHDD
                     LGDGIHYLYGAVGTGGSLCGTGRVLRERIPDLKVIGVEPVGSVVFGGRGAPYHQSGTGT
                     PEGSEIGGVVDYELIDQGLKASDSEAFETCRYLARNFGILIGGSAGGVVYKALERAQGA
                     GAGTVIVVLVCDGGDKYLDTVFNDDWMAANGLFDEQVVRRLAAMLR"
     gene            complement(5981..7180)
                     /gene="hisC"
                     /locus_tag="DDQ41_RS00760"
                     /old_locus_tag="DDQ41_00760"
     CDS             complement(5981..7180)
                     /EC_number="2.6.1.9"
                     /GO_function="GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (59-388). E-value:
                     7.6e-55. Score: 178.4. Matches aSDomain:
                     nrpspksdomains_DDQ41_RS00760_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="hisC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948647.1"
                     /locus_tag="DDQ41_RS00760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00760"
                     /product="histidinol-phosphate transaminase"
                     /protein_id="WP_262508316.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8e-53, bitscore:
                     178.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHALAASASAASASASASASAAPAPAATASLIRSEVAGLPRYDP
                     GADPDEVAALSGTRRVIKLSNNESPFGVSPAVAEAVRLGLADGVSRYPDPTGRRLADAV
                     GRSLDVPAGRVVLGNGSENILELLCQAVLDPGDLVVTQAPGFSLHETFPRVMGARVEKV
                     PVTADFGFDADAWRAALAAGPKLVFLANPCNPTGAMLRAGQLEHVVAATPRSALLVLDE
                     AYGEFARCDPEYPDGLEALRGLDRPWIVLRTFSKAYGLAGVRVGYGIASDAVLIQALDR
                     VRTPYNVNRPAQDAAVAALGDHRHLAETVRRTRLEIARVTGRLRAAGLGVVPSSTNFLF
                     IDTGRRSDRVARELHRAGIIVKAWREPGYENHIRASLSTPEDNDVFVRCLTEICAKGKS
                     "
     aSDomain        complement(6017..7003)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DDQ41_RS00760_Aminotran_1_2.1"
                     /evalue="7.60E-55"
                     /label="DDQ41_RS00760_Aminotran_1_2.1"
                     /locus_tag="DDQ41_RS00760"
                     /protein_end="388"
                     /protein_start="59"
                     /score="178.4"
                     /tool="antismash"
                     /translation="RVIKLSNNESPFGVSPAVAEAVRLGLADGVSRYPDPTGRRLADAV
                     GRSLDVPAGRVVLGNGSENILELLCQAVLDPGDLVVTQAPGFSLHETFPRVMGARVEKV
                     PVTADFGFDADAWRAALAAGPKLVFLANPCNPTGAMLRAGQLEHVVAATPRSALLVLDE
                     AYGEFARCDPEYPDGLEALRGLDRPWIVLRTFSKAYGLAGVRVGYGIASDAVLIQALDR
                     VRTPYNVNRPAQDAAVAALGDHRHLAETVRRTRLEIARVTGRLRAAGLGVVPSSTNFLF
                     IDTGRRSDRVARELHRAGIIVKAWREPGYENHIRASLSTPEDNDVFVR"
     gene            complement(7177..8865)
                     /locus_tag="DDQ41_RS00770"
                     /old_locus_tag="DDQ41_00770"
     CDS             complement(7177..8865)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948646.1"
                     /locus_tag="DDQ41_RS00770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00770"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_262508317.1"
                     /transl_table=11
                     /translation="MSGTRTNGTSGTAESTGTNGTAGAAESAGTAEAASAASAASANGT
                     AGTTSTTGTSGTAASSGTAGAAESAGTNGTAGAAESAGTAEAASANGTTGTAGNGVGWW
                     VRNSRALLRLALPLILTNFAYVALTTVDIVMLGRLGAVEIAAAGLAIALFNQLRTTGTG
                     LVTGVGNLVAEARVRDDRERIGALLFAGFFWATVCGVVFCAVLLLIGPLLVLLGQDPEV
                     VGKAGEFLTVLAPGMLPCLWFQNLRHFTTGLKRPGPLLAITLASVVVTIGLNYALIYGK
                     FGLPAFGFVGVAIATVTVFLLSFLAFVAVVLRDGVLRPYLVSPGARRWSGDAVRSVWRL
                     GLPISGTYASEAGFFSVLTLVIGTLGVDALAAQTVLNQIVYIVFMISAGLSHAASIHIS
                     EAAGADDYVTARRTGLLGTGWGVIAMLVVAVAYLAFPEPIVSLFISAEHAGNADILALT
                     ATGLLIAALMQVFDAAQNIGNGILRGIGDTAGPFRISLVGYWLIGLPAGCLLGVGAGWG
                     VEGVWIGQTIGLAATAAILLVAFLRRADRLHRAAAGASVPEPESS"
     gene            complement(8862..9842)
                     /locus_tag="DDQ41_RS00775"
                     /old_locus_tag="DDQ41_00775"
     CDS             complement(8862..9842)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890526.1"
                     /locus_tag="DDQ41_RS00775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00775"
                     /product="ornithine cyclodeaminase"
                     /protein_id="WP_109292695.1"
                     /sec_met_domain="AesA (E-value: 3.3e-102, bitscore: 339.8,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPSYAPPGQLWLLPQSQQEGLDLDHRQVIAVVERAYRALREGGS
                     NNPVKTIIDDPGHHSLSYSMVARDGGSGTVCFKAVYEFDPRRTRDGYRFHSFVFLVDDT
                     TGEPIALMDVVKLGPLRSSATTALFAREACPDARSALVVGTGVQGQAALPMLLAALPEL
                     ERLQVFGTYPDGLRAVRDSVDGREVEIVGDLRTAAGAADIVIGAAGLSATEEVRRDWMK
                     PGSVAVLLGYGVHADVCHGADYRIATDTAQMHATCDDLRGADGTPPSVDAQLPDVLLGR
                     APARRHPDDVVFAYNSGMAVTDAALGRYIADLARAAGRGEKVNFW"
     gene            complement(9887..11284)
                     /locus_tag="DDQ41_RS00780"
                     /old_locus_tag="DDQ41_00780"
     CDS             complement(9887..11284)
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891377.1"
                     /locus_tag="DDQ41_RS00780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00780"
                     /product="alanine racemase"
                     /protein_id="WP_262508318.1"
                     /sec_met_domain="AesB (E-value: 4.4e-149, bitscore: 494.9,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 1.2e-21, bitscore:
                     75.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLISRQLLERPTAGVRPLALTALRHPTVSRLLADHRVLLADLLDG
                     LGSPLHIVLPEIFEENVAALRRAFAEAGATADLLFAKKANKADCYATSAAALGVGIDVA
                     STPELVKALAGGVPGHRIGVSGPEKDDTLHALAVQHGCLVAVDSVSELRRLAATARGAR
                     RRAAVLLRTRTAGQPRSRFGLSAAERATAVGLCGELRDHIGLLGFSFHLNGYSTAERAT
                     AADEMIEHCLDARRRGSLSAEVVDIGGGLPVRYVEPRLWDAFLEQNGPAHYHAGKDFKD
                     FYPYGGQPAAQAVREIMAHPVDGGESLSAKAGRHGIRFLAEPGRALLDQAGFTLYRVQQ
                     VDDRRDADGYAIVTVAGSSFSLSEQWFNSDYLPDPLLLSAQPAADEPFPACVAGSTCLE
                     SDLVTWRKIGFPRPVRRGDHLVYLNTAGYQMDSNESPFHDAALPLKAVLRLGDGGAPPR
                     WRLDGAR"
     misc_feature    complement(11300..11315)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.07"
                     /tool="antismash"
     misc_feature    11303..11318
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.37"
                     /tool="antismash"
     misc_feature    complement(11303..11321)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.48"
                     /tool="antismash"
     misc_feature    11305..11319
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 25.32"
                     /tool="antismash"
     misc_feature    complement(11306..11321)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.86"
                     /tool="antismash"
     misc_feature    11313..11326
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.5"
                     /tool="antismash"
     misc_feature    complement(11797..11817)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.91"
                     /tool="antismash"
     gene            11912..12271
                     /locus_tag="DDQ41_RS00785"
                     /old_locus_tag="DDQ41_00785"
     CDS             11912..12271
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018385130.1"
                     /locus_tag="DDQ41_RS00785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00785"
                     /product="NADH-quinone oxidoreductase subunit A"
                     /protein_id="WP_245991405.1"
                     /transl_table=11
                     /translation="MARVSVWLPVLVLLGLTVAAVAGLYGLSALLSGGAAACAPVPFAG
                     GLMPREHAFSRFHVRWYPVTMIFLAFDMEMLFMYPWVRVVREMGPPAVIEMFLFLGILF
                     AAVTYAWREGALRWT"
     gene            12262..13644
                     /locus_tag="DDQ41_RS00790"
                     /old_locus_tag="DDQ41_00790"
     CDS             12262..13644
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944167.1"
                     /locus_tag="DDQ41_RS00790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00790"
                     /product="hypothetical protein"
                     /protein_id="WP_109292698.1"
                     /transl_table=11
                     /translation="MDLIGALPRLAARRPPVLLVTMPGATRERLAVEAELTGRGWPSAP
                     GPAAAAGLVVAGRAGGAQWLGDLWNGMPRPRAYVAVAHAGDAPHALDLLGRLLSSGREG
                     DAPRAVSAGAPRGAPGQGGGDGPDHHPGAPGSGARETPGDEDGRSGRGGQEGRDGRGQA
                     RGQGRGQGQGRKQGRALGLGLGQGRGQGQGQGQGHGGHRGGVAGLPMAGRADDRDGLRL
                     DRLHLPLGPALADWPAGLVLDVALQGDVLQSAEAHPWEAAPAGRYPFWGEPWLRAAGGE
                     AVTRGAAERRRCASHLDSVGRFLAVSGWPRPAARARRLRDRLLQGAAAGELAPEVLRLT
                     RGVARSRTLRWLTRGLGELPAGRARELGVTGPALAADGDVHARLRVWLGEIERSVHGMD
                     DPRALTGVDGPRGRLDGPRPPSRLLLAALLPLLPGAEFACARLILASFDPDPDEFAGAG
                     HG"
     gene            13637..14569
                     /locus_tag="DDQ41_RS00795"
                     /old_locus_tag="DDQ41_00795"
     CDS             13637..14569
                     /EC_number="1.6.5.9"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018844642.1"
                     /locus_tag="DDQ41_RS00795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00795"
                     /product="NADH-quinone oxidoreductase subunit H"
                     /protein_id="WP_109292699.1"
                     /transl_table=11
                     /translation="MAEAAPLWAVPVLPVALCLGAVAAAAFDAVVGGGSGRPGAGVLAA
                     ASAPLREGLRLLAQQRRTTPSADTALGRVGLGLVPVAAVLAAAVVPWGFVQVADPAVGI
                     VWFNAMEVLAWAAVWLAGWGPNSVLSLIGGYRFLAQGLAYELPHMFALTTAGLGAESLR
                     VSEVVGAQQGLWFAVWMPAAFAVYLLSAVAMSFWGPFGYPLGGDVAGGAVAEYSGVDRL
                     LLLGGRWLLLTATAAFSVPLFLGGGRGPLLPGWGWTLLKTAAVLAVLILARRMLPVLRA
                     ERYMEFAWMVLVPLTLVQALFVAVVVLNR"
     gene            14578..15141
                     /locus_tag="DDQ41_RS00800"
                     /old_locus_tag="DDQ41_00800"
     CDS             14578..15141
                     /EC_number="7.1.1.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018839839.1"
                     /locus_tag="DDQ41_RS00800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00800"
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="WP_109292700.1"
                     /transl_table=11
                     /translation="MLDNTVFSVLSAVAVGSGVMVFRFDSMARATYALLLSLLCVGGLL
                     VLLGLDYLGVVIVLMMTVEMAVMGVFMVMYMMNPAGLMPMSILHNRKGAAVVCAVVFLL
                     MALGIVLAPWPRRAGTADEDPTKALGESLMGPQMLTMMTLGFALFSTIVATVLLATHRG
                     RYDRLGDDLRARRADDPVPGGVGR"
     gene            15138..15443
                     /gene="nuoK"
                     /locus_tag="DDQ41_RS00805"
                     /old_locus_tag="DDQ41_00805"
     CDS             15138..15443
                     /EC_number="1.6.5.9"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /GO_process="GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="nuoK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944170.1"
                     /locus_tag="DDQ41_RS00805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DDQ41_00805"
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="WP_109292701.1"
                     /transl_table=11
                     /translation="MNLQPFLLVAAALFGVGLFGALSQQSVVMLMMGLELMLGGVILAA
                     AAVWHHIAPASADGQVLVVVAVTVMAVEMAIGFAVVTALFRAREVDMTDEAGDLRA"
ORIGIN
        1 catgcagtac gccgcggaga acatcaagcc cgtcaccctg gagctgggcg gcaagtcgcc
       61 gaacatcttc ttcgacgacg tctggtcggc cgacgacgag ctgagggaca aggcgttgga
      121 ggggttcacc atgttcgccc tcaaccaggg cgaggtgtgc acgtgtccgt cgcgggcgct
      181 gatccagcgg ggccactacg gcgagttcct cgacgcgggc atcgcgcgta ccgaggcgat
      241 cgtcccgggc caccccctcg acacggacac gatgatcggg gcgcaggcct ccaacgacca
      301 gttgcagaag atcctttcgt atctggacat cggccggcag gagggcgcga agatcctcac
      361 gggtggtcag cgcatcgagt acgacggcga gctggcgggc ggctactacg tcgagccgac
      421 gatcttcgag ggcgacaacc ggatgcgggt cttccaggag gagatcttcg ggccggtcgt
      481 cgcggtgacc tccttcgccg acttcgacga cgcgatcaag acggcgaacg acaccctcta
      541 cggcctcggc gccggggtct ggacgcgcga cgtcaaccag gcgtaccgcg ccggccgagc
      601 gatccaggcc ggccgggtct ggacgaactg ctaccacgcc taccccgcgc acgccgcctt
      661 cggcggctac aagcagtcag gtatcggccg tgagacgcac aagatgatgc tggaccacta
      721 ccagcagacg aagaacctgc tggtgagcta ctcgccgaag aagctcggct tcttctagcg
      781 gcacgaaaga cggcactgtg agatccgcag gtggatgacc tccgccggac gcatggccgc
      841 gtagtacatg cagccgaaga acgcctcaag gtgcgggcca cgtccccgtt gtttgccaac
      901 agcggccagc aggcgagcaa ccggggtcgg gttcggcaca caggccgggt ccacttcctc
      961 actcacccca ggggcctgcc acctgaccct tgcgagcggg ttctccccga agtatccctt
     1021 gtcgacggca gttccgagga cctcgctgaa ggccgatttc tttccgcagg gcggtcttcg
     1081 ccgcagcgga ctcgccgtcg atcctccgcc caagcgcgcc caacgcccgg cccacgacat
     1141 ctggttccgt cagcctggat ccaccgcgtg aattctgatc ttcagtatcg ggtgggctcg
     1201 gggtgatctt tcggggtgcg ggcagcgcga tgggccgggt ggccgtccgg tgcggggtct
     1261 ccgaggtcct tccggatcgt gggcggcagg gtggtcgccc ggttcaggtg agcatgcgct
     1321 ggccggtggc tgtccacagg ccggtgaagt cgtcggccca ccgccagtgc ctgggcaggt
     1381 ggagggtgaa gcggcgggct ccggcggcga tccgggcggg gatgtcgatc aggtggcggc
     1441 ggatggtgcc ggtcctcgcc ctggcgtgga aggcggaggc gaggtggccg ctcgcgcggg
     1501 tgaggttgta aggggtggcc gccagggggc caggcggcgt tcgcggtgaa cttccccgac
     1561 ggcaggtggg cgagcgcgga gtcttccagg tcggcgaaga cctgctcgat cacggcgtgt
     1621 tcgcggtgca tcggctcggc ctgggccagg acgaaggggc atggtcacga aggccggact
     1681 ccgcaccgtg tccgccaccc gccgcgccag cggtgggggc ggacactacg gctcgaaacc
     1741 gtcacgactc gatgtcaggc gactgccgcg ctttgcgggg tgagccagaa atcgagcagg
     1801 gcggaggcca cttcggatgg tttgtgcaca tttcctcatg accacgagac gcccgttctc
     1861 agaacctcgg gatccagggt ctcgcgtgtc caggatcgag agtcgagacc catcaacgtc
     1921 cctgcggttg agtggcggcc gtccggtcgg cggtggcgcc caggtaggtg atgcggaggg
     1981 tgccggtggc gggttcgcgg tcgacgagta cccggacgcc gtagaccgac tcgatcaggt
     2041 cgggggtcag cacggcctcc ggggagcccc cggcggccac ctgcccccgg tcgaggacga
     2101 cgacgtggtc gcagtaccgg gcggcgaggt tgaggtcgtg cagggcgacg acgcaggtga
     2161 cgtccaggtg cgtcagcagg tcgagcagtt cgagctggtg gcggatgtcg aggtggttgg
     2221 tgggttcgtc gaggaggatc tcccggggct cctgggcgag ggcgcgggcg agttgggtgc
     2281 gctgcttctc ccctccggag agggtgtgcc agctccggtg ctgcttgtcg ctgatctcgg
     2341 tccgttccag cgccgcgtcg acgatccgcc ggtcgcgctc ggtcagcgcg tcgaagcggc
     2401 cgcggaacgg tgtgcggccg agttccacga cctggcggac gttgacgtgg tggtgggcgg
     2461 acacgtcctg ttcgacgacg gcgagccgcc gggcccgcac cctgcggccg aggtcgtcca
     2521 ggctggtgtc gtcgtagcgg atggttccgg tgtcggggcg gcgcagaccg gcgagcaggc
     2581 gcagcagtgt cgacttgccc gagccgttgg ggccgaggag gccgacggtc ttcccgtccg
     2641 gggccgccat gtcgatgccg tcgagcagcc ggtggccctt gaccgaccag gagagtcggg
     2701 tggtggtgat gcggcccatc aggactccag acgcttcagg accagtgcga aggcgggcgc
     2761 gccgagcagc gcggtgatga cgccggcggg cagttcgtgg ggcgcgaacg ccgtgcgtgc
     2821 gaacacgtcc acccagatga ggaagacggc gccgacgatc gcggacaggg gaagcagggc
     2881 gcggtgcgtc ggaccggcca ggatgcggac ggcatgcggg acgagcagcc cgatgaagcc
     2941 gatcgcgccg gaggcggcca cggcggccgc cgtcatgacc gaggtcagca ccatcagccg
     3001 gacgcgggcc gcggtgacgt tgacgcccag ggtttcggcg gagtcccacc cgaaggtgaa
     3061 ggcgtcgagg gcgggcgcga ggaactgcac ggcgaccacc ccgatcagga tgatcacgac
     3121 ggtgacggcc gccccttccc accgggcgcc cgcgagggtg ccgagcagcc agtaggtgaa
     3181 gccccgggtg gagtcggcgt ccccgccgac catgaggatc accgaggtga ccgcggcgaa
     3241 gaactgggac accagcacgc cggtcagcac cacgcgggag gggctggcga cgcgcccccc
     3301 gccgagcagg agcagcagta cgccgaagga gaccaggccg ccggcgaagg ctccggtcga
     3361 cagggagatg cttccgccga cgcccagcag gagcacggcg accgcgccgg tggaggcgcc
     3421 ggaggagact cccagcaggt aggggtcggc cagggggttc ctggtgaccg cctggaggat
     3481 cgctccggag accgcgaggg ccatgccgac ggcggcggcc agcagcacgc gcgggaagcg
     3541 ggactcccag atcagggcgt catggagtcc cgggagcggc gcggtggggg cgatggagtc
     3601 caggccgata tgccgcagga tcgtcgagac gacgtccagg ggctggatgt ccgcgctccc
     3661 gaacagtgtc gcggtgacga ccgacaccag cagtccggcc gcggccagga ggaggagcgc
     3721 cgccgtgcgg gcgcgccgcg cgcccaccgg aaccgtcgcg cggctggggg ccgggttcct
     3781 ggtgggcgcg gcggacttgt gtgaaccggt ggtcatgggg ttcgcgacta cccgagcttg
     3841 ttcaggccgt cgacgagcgc gggaacggcg gacgcgctgc cgtatcccgg gtccatgtgg
     3901 gtgccgggga tggtgatgaa ccggtcgccc ttcaccgcgg ggagcttgct ggtgaggggg
     3961 tccttcttca gcagttcgat cttctcctcg gccgtgtcgt tgggttcgcc ccgggtgagg
     4021 tcggccagga tgatgacgtc cgggttgcgg gcggcggcct cgtcccaact cacctcggcc
     4081 catttggact tggcgtcggc gaagatgttc tcgactccga cgagttccga gatgtgctgc
     4141 ggcaggccac cggggccggc ggcccacgga gtgccctcga aggtggagta gaaccacatc
     4201 accttcaacg gctcgtcccg cttctcgacc tcgccgacgg ccttgtccac cagggccttc
     4261 tgcgcggccg cgagcttctc ccccgcctcg gggacgttca tgatcttccc cagtcggcgg
     4321 tactcctcga agagcatgtc gaagtccgcg tcggcaacgg cctcgtggta ggagcagtcg
     4381 aactcggtca gataggtggg cacgcccagg tcgtgcagtt ccttgcggtc gccggcctcc
     4441 tccttggtga ggaagctcgc gaacgagctg tagacgaagt cgggctgcgc ctccagcagt
     4501 ttctcgtgct tgaccgtgtc gcccttcgca gacagctgcg ggatcttccc gtactgctcg
     4561 gcgatcgcgt ccggggtctt ctcgatctcg tatcccgacc cgatgatccg gtcgcccacc
     4621 ccgaggtgga tgaggatctc cgcggcggtc tggttgaggg tgacgacctt ctcaggcgcg
     4681 gccttgtagg tcacgtcgac gccgcagttc tcgagggtga gcggataggc cgccgcgccc
     4741 ttcgcggact tcgcgtcctg cccgccgtcg tcgggggacc ggtctgcggc gcaccccgcg
     4801 accgccagta tcgccagggc cgtacacgtt ctgattatca ttttcgtttt catcagcggc
     4861 agagtaccag gtcgcggcgg ggagtgaagc gggccccggc tcggccgggt aaaccgccgg
     4921 accgcccggc gggccgggcc ggcgcaccgg tggatgccac cggtgcgccg ggtgtcccgc
     4981 ccgttccggc ggtgcgggcg ctatcgcagc atcgcggcca gccgacggac gacctgctcg
     5041 tcgaacaggc cgttggccgc catccagtcg tcgttgaaca cggtgtccag gtacttgtcg
     5101 ccgccgtcgc agaccagcac gacgatgacg gtcccggccc ccgcgccctg cgcccgctcc
     5161 agggccttgt agaccacgcc gcccgccgaa ccgccgatca ggatgccgaa gttcctggcc
     5221 aggtagcggc aggtctcgaa ggcctccgag tcactggcct tgagcccctg gtcgatcagt
     5281 tcgtagtcga cgacaccgcc gatctccgag ccctcggggg taccggtacc ggactggtgg
     5341 tagggcgcgc cccggccgcc gaagacgacg gaccccaccg gctcgacacc gatgaccttc
     5401 aggtccggga tgcgttcccg caggacgcgg ccggtgccgc agagcgaacc accggtgccg
     5461 acggccccgt acaggtagtg gatgccgtca ccgagatcgt cgtgcagctc gcgggcgagc
     5521 ggccggtagc cgttggggtt gccctggttg cggtgctgcg cggtccagta cgcgccgtgc
     5581 tcggccgcga gccgctcggc cacggtgtcg cgttcggcgg tggcgaggcc ttcctcgtcc
     5641 ccggcgacgt tgaggatgtc ggccccgtag gcgagcatgc cgcgcagttt gtcggtgctg
     5701 gagtggttgt ccaccacggc ggtgaacttg tatccgcgtt cggcggcgat gagcgccaga
     5761 ccgagcccgg tgttgcccga ggtggactcg accagccatc cgccgggggt gagcagcccg
     5821 gcctcctccg cctcctcgac catgctcctg gccatccgga tcttggcggt gccggtgggg
     5881 ttgtactgct ccaacttcag cacgaccgtc gccgaaccgt ccgcaaccgg cagttcgagc
     5941 aggggcgttc gcccgatcag atcggatatc ctggttctta tcacgacttg cccttcgcgc
     6001 agatctccgt caggcaccgc acgaagacgt cgttgtcctc gggggtcgac agggaggctc
     6061 ggatgtggtt ctcgtatccc ggctctcgcc acgccttgac gatgattccg gcgcggtgca
     6121 gttcccgggc gacccggtcg gagcggcggc cggtgtcgat gaacaggaag ttggtcgacg
     6181 acgggaccac gcccagtccc gcggcacgca gccggccggt gaccctggcg atctccagac
     6241 gggtccggcg gaccgtctcc gccaggtggc gatgatcgcc cagcgcggcg acggcggcgt
     6301 cctgggccgg ccggttgacg ttgtacgggg tgcggacccg gtccagtgcc tggatcagga
     6361 ccgcgtcgga ggcgatgccg taccccaccc ggacgcccgc cagaccgtag gccttggaga
     6421 aggtgcgcag cacgatccac ggccggtcca ggccgcgcag ggcctccagc ccgtcggggt
     6481 actccgggtc gcaccgggcg aactcgccgt acgcctcgtc gagtaccagc agggccgacc
     6541 gcggggtcgc ggccacgacg tgctccagct ggccggccct gagcatcgcc ccggtggggt
     6601 tgcacgggtt ggcgaggaag acgagcttcg ggccggcggc cagtgcggca cgccaggcgt
     6661 ccgcgtcgaa cccgaagtcc gcggtgaccg ggaccttctc gacccgggcg cccatgaccc
     6721 gggggaaggt ctcgtgcagg ctgaacccgg gcgcctgggt gacgaccagg tcaccggggt
     6781 cgagtacggc ctggcacagc agttccagga tgttctccga tccgttgccg agcacaaccc
     6841 gcccggccgg cacgtccaga ctcctcccga cggcgtcggc cagccgtctg ccggtggggt
     6901 cggggtagcg gctgacgccg tcggccaggc ccagccgtac ggcttcggcg accgccggag
     6961 agacaccgaa cgggctctcg ttgttggaca gtttgatcac gcggcgggtg ccgctgaggg
     7021 cggccacctc gtccgggtcg gcgccggggt cgtagcgggg caggcccgcc acttcgctgc
     7081 gtatcaggga ggccgtggcg gccggggccg gggccgcgga ggcagaggca gaggcagagg
     7141 cagaggcggc agaggcggag gcggcgaggg cgtggttcat gaggactccg gttccgggac
     7201 ggatgcgccg gcggctgctc ggtggagccg gtcggctcgg cgcaggaacg cgaccagcag
     7261 gatggcggcg gtggcggcga ggccgatggt ctggccgatc cagacgccct cgacgcccca
     7321 gccggcaccc accccgagca gacagcccgc gggcagcccg atcagccagt agccgacgag
     7381 ggagatccgg aacggcccgg cggtgtcccc gatgccgcgc aggatgccgt tgccgatgtt
     7441 ctgcgccgcg tcgaagacct gcatcagtgc ggcgatcagc agtccggtcg cggtcagcgc
     7501 gaggatgtcc gcgttgcctg cgtgctcggc cgagatgaag agggacacga tcggctccgg
     7561 gaacgccagg taggcgacgg cgacgaccag catggcgatg acgccccagc ccgtaccgag
     7621 gagccccgtt ctgcgtgctg tcacatagtc gtcggcaccg gcggcctcgc tgatgtggat
     7681 cgacgccgcg tgcgacagtc cggcggagat catgaagacg atgtagacga tctggttcag
     7741 cacggtctgt gcggccaggg cgtcgacacc gagggttccg atgaccagcg tgagcacact
     7801 gaagaacccc gcctccgagg cgtatgtgcc cgagatcggc aggcccaggc gccagaccga
     7861 ccggaccgcg tccccggacc agcgccgcgc gccgggcgag acgaggtacg ggcggaggac
     7921 tccgtcgcgc aggaccaccg cgacgaacgc caggaaggac agcaggaaca ccgtgacggt
     7981 ggcgatcgcc acaccgacga agccgaacgc gggcaggccg aacttgccgt agatcagcgc
     8041 gtagttcaga ccgatggtca cgacgaccga ggccagtgtg atggccagca gcggaccggg
     8101 ccgcttgagg ccggtggtga agtgccgcag gttctggaac cacaggcagg gcagcatgcc
     8161 cggcgccagg accgtcagga actcgccggc cttgccgacc acctccgggt cctgccccag
     8221 gaggacgagc agcgggccga tcagcaggag caccgcgcag aacaccacac cgcacacggt
     8281 cgcccagaag aaccccgcga acagcagcgc gccgatccgc tcccggtcgt cccgcacccg
     8341 tgcctcggcc accaggttgc cgactccggt gaccagcccg gtgccggtgg tgcgcaactg
     8401 gttgaacagc gcgatggcca ggccggcggc ggcgatctcg accgcgccga gcctgcccag
     8461 catcacgatg tccacggtgg tcagcgctac ataggcgaag ttggtcagga tcagcgggag
     8521 cgcgagcctg agcagcgccc gtgagttccg gacccaccag ccgacgccgt tgcctgccgt
     8581 cccggtcgtg ccgttcgcac tggccgcctc cgcggtgccg gccgactccg ccgcaccggc
     8641 cgtgccgttc gtgccggccg actccgccgc accggccgtg ccggacgacg ctgccgtacc
     8701 gctcgtaccg gtcgtactgg tcgtaccggc cgtaccgttc gcactggccg cactggccgc
     8761 actggccgcc tctgcggtgc cggccgactc cgccgcaccg gccgtgccgt tcgtgccggt
     8821 cgactccgcc gtaccgctcg tgccgttcgt tcgggtgccg ctcaccagaa gttgaccttt
     8881 tccccgcgcc cggccgcccg tgcgaggtcg gctatgtacc ggccaagcgc ggcgtcggtg
     8941 accgccatac cgctgttgta ggcgaagacc acatcgtccg gatggcgccg ggcgggggcc
     9001 cggccgagca ggacgtccgg caactgggcg tcgaccgacg gcggagtgcc gtccgcaccc
     9061 cgcaggtcgt cgcaggtggc gtgcatctgg gcggtgtccg tggcgatccg gtagtccgcg
     9121 ccgtggcaca cgtcggcgtg tacgccgtag ccgagcagta ccgcgaccga gcccggcttc
     9181 atccagtcgc gccggacctc ctccgtggcg gagaggcccg cggcgccgat cacgatgtcg
     9241 gccgcaccgg cggcggtccg gaggtccccg acgatctcga cctcgcggcc gtcgacgctg
     9301 tcccggacgg cgcgcagacc gtccgggtag gtgccgaaca cctgcaaccg ctccagctcg
     9361 ggcagcgccg ccagcagcat cggcagggcc gcctgcccct ggactccggt gccgacgacc
     9421 agggcgctcc gcgcgtcggg gcaggcctcg cgggcgaaca gcgcggtggt ggccgaggac
     9481 cgcagcgggc cgagcttcac cacgtccatc agggcgatcg gctccccggt ggtgtcgtcg
     9541 acgaggaaga cgaacgagtg gaaccggtag ccgtcacggg tgcggcgcgg gtcgaactcg
     9601 tagacggcct tgaagcacac ggtgccgctg ccgccgtccc gggccaccat cgaatagctg
     9661 agggagtggt ggccgggatc gtcgatgatc gtcttgacgg ggttgttcga accgccttcg
     9721 cgcagcgcgc ggtaggcccg ctcgacgacc gcgatcacct gccggtggtc gaggtccagc
     9781 ccttcctgct gcgactgcgg cagcagccac aactgcccgg gcggggcgta gctcggtgac
     9841 atacgagggt tctcctctgg tggtcggatt gcgtcggttc ggggtctcat cgggctccgt
     9901 ccagtcgcca gcgcggcggg gccccgccgt cgccgagccg gagaacggcc ttcaacggga
     9961 gtgcggcgtc gtggaacggc gactcgttgg agtccatctg gtagccggcc gtgttgaggt
    10021 agaccaggtg gtcgccgcgc cgtaccggcc gcgggaagcc gatcttccgc caggtcacca
    10081 gatcgctctc caggcaggtc gagcccgcca cgcaggccgg gaacggctcg tcggcggcgg
    10141 gctgcgcgga cagcagcagc gggtcgggga ggtagtcgct gttgaaccac tgctcggaga
    10201 ggctgaagct gctgcccgcg acggtgacga tcgcgtaccc gtcggcgtcc cgccggtcgt
    10261 cgacctgctg tacccggtac agggtgaatc cggcctggtc cagcagcgcc cggccgggct
    10321 cggcgaggaa gcggataccg tggcgcccgg ccttcgccga caggctctcg ccgccgtcga
    10381 cggggtgcgc catgatctcg cgtaccgcct gggcggcggg ctgccccccg tacggataga
    10441 agtccttgaa gtccttgccc gcgtggtagt gggccggccc gttctgctcg aggaacgcgt
    10501 cccagagccg cggctcgaca tagcggaccg gcaacccgcc gccgatgtcg accacttccg
    10561 cggagagcga gccccgccgt ctcgcgtcga ggcagtgctc gatcatctcg tccgccgccg
    10621 tggcgcgttc cgccgtggag tagccgttca gatggaagga gaaccccagc aggccgatgt
    10681 ggtcgcggag ttccccgcag aggccgacgg cggtggcgcg ttcggcggcg gacagcccga
    10741 agcggcttcg cggttgaccc gccgtgcggg tcctcagcag caccgcggcc cggcgccgtg
    10801 cgccccgcgc ggtcgcggcg agccggcgga gttcactgac cgagtcgacg gcgaccaggc
    10861 agccatgctg aacggcgaga gcatgcagag tgtcgtcctt ctccgggccg gacaccccga
    10921 tccggtgtcc cggcactccg ccggccagcg ccttgacgag ttcgggggtg ctggcgacgt
    10981 cgatccccac tcccagggcg gcggccgacg tggcatagca gtcggccttg ttggccttct
    11041 tggcgaacag gaggtcggcg gtggcgcccg cctcggcgaa cgcccgccgg agtgcggcga
    11101 cgttctcctc gaagatctcg ggcagcacga tgtgcagtgg tgaccccagg ccgtccagga
    11161 ggtcggccag caggacacgg tgatccgcca ggagcctgga gaccgtggga tgccggagtg
    11221 cggtgagcgc caagggccgg actccggccg tggggcgctc cagcaactgt cgtgagatga
    11281 gcacctggta cttctatacg attatgacag tcattttcaa ttgaacaggg acaggggctc
    11341 gacttacagg ggggggagga aagcggacga atcgccgccc atcgggccgc tcgctccgac
    11401 gagtcgagcg ccggaacgag tcccgcgcgg acgccgcgtc ggcgggaagc ccctcatggg
    11461 ggacgaccgg gcggggcccc gttcgggccg ggcctcgtga cgacccgggt gaccgcctgc
    11521 tcccccgcgg cgccgggggc gcttgcgcct gcttgaccgc gggacccgct cgtcgcgtac
    11581 ggccccccgg ccggggggag tcacaccggc tgggagcggc ccgcgccggt gctcccgccg
    11641 acgactcccg ccgggccgcc gggccgccgg ggcacggcgg cagagcagca caacggcaca
    11701 gcgacacggg cggcgcggcg gcacggcggc gcggcggcac ggctcaacac gcccgtaccg
    11761 gccgggaacc ggatgcccgg catgcccggc cggccgcaca caggcggtga tgtgcttatc
    11821 gctccgcggt gttgccgtga gggagccgtt ccggtgggcg gagcagcacc gcctgtgcgc
    11881 cttccaggcg tacggccgac ggctcggcag tatggcgcgg gtgagcgtct ggttgcctgt
    11941 actcgtcctg ctcgggctga ccgtggcggc ggtcgccggc ctctacgggc tgagcgcgct
    12001 gctgtccgga ggagccgccg cctgcgctcc ggtgccgttc gccggcggcc tgatgccgcg
    12061 tgaacacgcc ttctcccgct tccatgtcag gtggtacccg gtcaccatga tctttctggc
    12121 cttcgacatg gagatgctgt tcatgtatcc gtgggtcagg gtggttcggg agatgggccc
    12181 gcccgcggtc atcgagatgt tcctgttcct gggcatcctc ttcgcggcgg tgacgtacgc
    12241 ctggcgcgag ggcgcactcc ggtggacctg atcggcgcgc tgccccgact ggccgcccgg
    12301 cggcctcccg tgctgctggt gaccatgccc ggcgccaccc gggagcggct tgcggtggag
    12361 gcggaactca ccgggcgggg ctggccgtcg gcccccggcc cggccgccgc cgcggggctt
    12421 gtcgtggccg gccgggcggg cggcgcgcaa tggctcggcg atctgtggaa cggcatgccc
    12481 cggccgagag cgtatgtcgc cgtcgcccat gccggcgacg cgcctcacgc gcttgatctg
    12541 ctgggcaggt tgctgtcctc ggggcgtgaa ggcgacgcgc cccgggcggt ctccgccggc
    12601 gccccccgcg gggcgccggg ccagggcggc ggcgacggcc cggaccacca cccgggggcg
    12661 ccgggcagtg gggcccgtga gacccccggc gacgaggacg gccggagcgg ccgcggcggc
    12721 caggaaggcc gcgacggccg cgggcaggcg cgggggcaag gacgggggca aggacaggga
    12781 cggaagcagg gacgggcact gggactggga ctggggcagg gacggggaca gggacagggg
    12841 caggggcagg gccacggcgg gcatcgcggt ggtgtcgccg ggctgccgat ggccgggcgg
    12901 gccgacgacc gtgacggcct gcggctggac cggctgcatc ttccgctggg accggcgctc
    12961 gcggactggc cggccggcct ggtcctggat gtcgcgctcc agggagacgt gctccagtcg
    13021 gccgaggcgc atccgtggga ggccgctccg gccgggcggt atccgttctg gggcgaaccg
    13081 tggctgcgtg cggcaggggg cgaggcggtg accagggggg cggcggaacg ccggcgctgt
    13141 gcgtcccatc tggacagcgt gggccggttc ctggccgttt cgggatggcc tcggcccgcc
    13201 gcccgggcgc gccgtctgcg cgaccggctg ctgcagggcg ccgcggcagg cgaactcgct
    13261 cctgaagtcc tgcggctgac ccgcggggtc gcccgttcgc ggacgctgcg gtggctgacg
    13321 cgcgggctcg gggaacttcc cgccgggcgg gcccgggaac tcggggtcac gggcccggcg
    13381 ctcgccgccg acggtgacgt ccatgcccgt ctgcgcgtct ggctggggga gatcgagcgc
    13441 tccgtgcacg gcatggacga tccccgcgcc ctcaccggcg tcgacggtcc ccgagggcgg
    13501 cttgacgggc cccggcctcc ttcccggctg ctgcttgccg ccctgctgcc cctgctgcca
    13561 ggcgcggagt tcgcctgcgc acggctgatc ctggcgagtt tcgatccgga tcccgacgag
    13621 ttcgccgggg ccgggcatgg ctgaggcggc gccgctgtgg gcggtcccgg tcctgccggt
    13681 tgccctgtgc ctcggggcgg tcgccgccgc cgccttcgac gcggtggtgg gcgggggctc
    13741 cgggcggccc ggcgccggtg tgctcgctgc ggcgtcggcg ccgctgcggg aggggctgcg
    13801 gctgctcgcg cagcagcggc ggaccacgcc ttcggccgac accgcgctcg ggcgcgtcgg
    13861 tctcggcctg gtgccggtgg ccgcggtcct cgccgcggcg gtcgtcccgt ggggcttcgt
    13921 gcaggtggcc gatcccgcgg tcgggatcgt gtggttcaac gcgatggagg tactggcctg
    13981 ggcggcggtc tggctcgcgg gctgggggcc gaactcggtg ctgtcgctga tcggcggcta
    14041 ccgcttcctc gcgcaggggc tcgcctacga gttgccgcac atgttcgcgc tgaccaccgc
    14101 gggcctgggc gcggagtccc ttcgggtgtc ggaggtggtc ggggcccagc aggggctgtg
    14161 gttcgcggtg tggatgccgg ccgcgttcgc cgtctatctg ctgagcgcgg tggccatgtc
    14221 cttctggggc cccttcggtt atccgctggg cggggacgtg gcgggcggcg ccgtcgcgga
    14281 gtacagcggg gtggaccgtc tcctcctgct cggcggccgg tggctgctgc tcacggccac
    14341 cgcggcgttc agcgtgcccc tgttcctcgg cggcgggcgg ggacccctgc tgccgggctg
    14401 gggatggacg ctgctgaaga ccgccgccgt cctcgcggtg ctgatcctgg cgcggcggat
    14461 gctgccggtg ctgcgggcgg agcgctacat ggagttcgcc tggatggtgc tggtgccgct
    14521 gacgctggtg caggcgctgt tcgtcgccgt cgtggtactg aaccgctagg gagcggcatg
    14581 ctggacaaca cggtcttctc ggtcctctcg gccgtcgcgg tgggcagcgg ggtcatggtg
    14641 ttccgcttcg actccatggc gcgggcgacg tatgcgctgc tgctgtcgct gctctgcgtc
    14701 ggcgggctgc tcgtcctgct cgggctcgac tacctcggcg tggtcatcgt gctgatgatg
    14761 accgtcgaga tggccgtcat gggcgtattc atggtgatgt acatgatgaa cccggcaggg
    14821 ctcatgccga tgtccatact gcacaaccgg aagggcgcgg cggtcgtctg cgcggtggta
    14881 tttctgctga tggccctggg catcgtcctc gcgccgtggc cgcggcgggc ggggacggcg
    14941 gacgaggacc cgaccaaggc gctgggtgag tccctgatgg gcccgcagat gctgacgatg
    15001 atgaccctgg gtttcgccct gttctccacc atcgtggcca cggtgctgct ggccacccac
    15061 cggggccgct acgaccggct gggggacgac ctgcgggcac gccgcgccga cgacccggtg
    15121 ccgggagggg tcggccggtg aacctgcaac cgttcctgct ggtcgccgcg gcgctgttcg
    15181 gcgtggggct gttcggtgcg ctgagccagc agtccgtggt gatgctgatg atggggctgg
    15241 agctgatgct cggcggcgtc atcctggccg ccgcggccgt ctggcaccat atcgcccccg
    15301 cctccgccga cgggcaggtg ctggtcgtcg tcgccgtcac cgtgatggcg gtggagatgg
    15361 cgatcggatt cgcggtggtc accgccctgt tccgggcccg ggaggtcgat atgaccgacg
    15421 aggcgggaga cctgagggca tgagcgcact gctgtgggca ctggtcgccc tgccgccggc
    15481 gagcggcgtg ctgctgtgcc tcgcgggacg gcgggccgac cgcgtggccc ccgccgccgc
    15541 ggtcgccgtc gccgccgccg cggtcgtcct cgccgtggcg gcggccttcg cccagccgcg
    15601 ggccggcgcc ccgctgctgc ggggagcggc gttcggtctc gcggtggacg gcctgtcggg
    15661 cctgatggtg gtgaccgtca ccgccgtcgc cgctctcgtc gtcctcttcg gcgccgcgga
    15721 catcggaccg gagcaggcgc gagcgaggtt cttcggcctg atgctgcttt tcgtcggggc
    15781 gatgctggtc accgtcaccg cgacgaccct gcccgccctg ctgatgggct gggaggtcat
    15841 gggagccacc tcgtgggcgc tgatcggcta ctggtggcgc gacccggtgc ggggcgaggc
    15901 ggccggagtc gcgttcctca ccacccggac cgcggacctc gggctctacc tggccgccgg
    15961 cgccgcgctg gccgggggcg gcagcctggc cctggcggac ctggaccagg tcgcgcggcc
    16021 ctggctgcac ctggtggcgg cgggggtgat cgcggccgcg ctggggaagt cggcccagct
    16081 gccgttcagt ttctggctgt cgagggcgat gcagggcccc agcccggtgt cggctcttct
    16141 gcactcggcg gcgatggtcg tcgccggggc gtacctcctg atccgaaccg gcccgctgct
    16201 ggccgcgtcg ggctggggca gcgacgccac ctcctggatc ggtgccgcca ccgcgttcgc
    16261 gctcggactc gtcgccgtgg cgca
//
