LOCUS       NZ_KZ819178            21311 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. CS131 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ819178
VERSION     NZ_KZ819178.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS131
  ORGANISM  Streptomyces sp. CS131
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7968990)
  AUTHORS   Malmierca,M., Ceniceros,A., Mendez,C., Salas,J.A. and Olano,C.
  TITLE     Genome analysis of twelve Streptomyces spp. associated with Peruvian
            leafcutter ants
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7968990)
  AUTHORS   Malmierca,M., Ceniceros,A., Mendez,C., Salas,J.A. and Olano,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2018) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 88.88x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003116755.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 09:38:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,994
            CDSs (total)                      :: 6,912
            Genes (coding)                    :: 6,769
            CDSs (with protein)               :: 6,769
            Genes (RNA)                       :: 82
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 41 of 143
            Pseudo Genes (incomplete)         :: 122 of 143
            Pseudo Genes (internal stop)      :: 12 of 143
            Pseudo Genes (multiple problems)  :: 31 of 143
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:40:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6688266
            Orig. end                         :: 6709577
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ819178.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Professor JA Salas
            laboratory.
FEATURES             Location/Qualifiers
     region          1..21311
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="30"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21311
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21311
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11311](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11311
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(902..1921)
                     /locus_tag="DBP20_RS30145"
                     /old_locus_tag="DBP20_30165"
     CDS             complement(902..1921)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965313.1"
                     /locus_tag="DBP20_RS30145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30165"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_109180667.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.1e-15, bitscore:
                     57.1, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 2.7e-24,
                     bitscore: 84.2, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIGLIGTGRIGTFHAEVLSRHPAVDALLLADADPERAAASALRT
                     GGTAVAVDDLFSGADEAPAPPDAVVICSATAAHAGLIARAARAGLPAFCEKPIALDLPG
                     TLAALAEVEAAGSLLQLGFMRRFDAGYGEARAAVRDGRLGRLHTVRAVTSDPAPPPAAY
                     LPLSGGLYRDCLVHDFDILRWVTGREVSEVYATGSDTGPAMFREAGDVDTAAALLTLDD
                     GTLATATATRCNGAGYDVRMELAGELDQIAVGLDDRTPLTSAEPGGPGAPAKPWPGFLE
                     RFAPAYEAELDAFLRVVRGELANPCDGREALHALRIAEACEVSRRERRPVAMDEIPGG"
     gene            2020..2778
                     /locus_tag="DBP20_RS30150"
                     /old_locus_tag="DBP20_30170"
     CDS             2020..2778
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072635.1"
                     /locus_tag="DBP20_RS30150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30170"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_010072635.1"
                     /transl_table=11
                     /translation="MTAHGTDRPLPLSVDRTSPVPLYFQLAQQLEAAVEQGRLAPGALL
                     GNEIDLASRLGLSRPTVRQAIQTLVDKGLMVRRRGVGTQVVHSQVRRPLELSSLYDDLE
                     AAGQRPATAVLRNTTEPATAEVAAALGVAEGSEVHLVERLRSAHGEPMALLRNHLPPGL
                     VPLRTDELEATGLYRLMRAAGITLHSARQTVGARAATVGEARDLDEEPGAPLLTMERVT
                     YDDTGRVVEFGSHVYRAARYAFEFQLLVRP"
     misc_feature    2966..2979
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            3161..4135
                     /locus_tag="DBP20_RS30155"
                     /old_locus_tag="DBP20_30175"
     CDS             3161..4135
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153146.1"
                     /locus_tag="DBP20_RS30155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30175"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_109181659.1"
                     /transl_table=11
                     /translation="MGAVLAVMLAAAGCSSTGGKRAEERAAEAAEGRAAVNTPRWTFAM
                     VTHSGDGDTFWDIVQKGAEQAALKDNINFLYSHNDEANQQAQLVQTAIDKKVDGLIVSL
                     AKPDAMKAVVAKAVKAGIPVVTVNSGSAESKEFGALTHIGQDETIAGEAVGDELNNRDR
                     KKALCVLHEQGNVGHEQRCAGAKKTFDGTMQNLYVDGTNMPDVTASIEAKLQSDKSIDA
                     VVTLGAPFADAAVQAKQTAGSKAEIDTFDLNAKVAAGLQTDKLGFAVDQQPYLQGYEAV
                     DLLWLYRYNRNVLGGGQPVLTGPQVITKDDADALADYTKRGTR"
     gene            4132..5187
                     /locus_tag="DBP20_RS30160"
                     /old_locus_tag="DBP20_30180"
     CDS             4132..5187
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965310.1"
                     /locus_tag="DBP20_RS30160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30180"
                     /product="ABC transporter permease"
                     /protein_id="WP_032767907.1"
                     /transl_table=11
                     /translation="MSGSTAAPEKPAQLDERLVHTSPLRKLLGRPELGSVVGAVAVFLF
                     FAIVADSFLQASSFGTVLYAASVLGIMAAPVALLMIGGEFDLSAGVLVTSSALISSMFS
                     YQMTANVWVGVLVSLLVTLAIGAFNGFMLTRTELPSFIITLGTFLMLTGLNLGFTKLIS
                     GTVSTKAIGDMEGFDSAHALFASTLTVGSVEFKVTILWWIALVAVATWILLRTRFGNWI
                     FAVGGQADAARAVGVPVVRTKIGLYLGVAFAAWISGQHLLFSYDVVQSGEGVGNELTYI
                     IAAVIGGCLITGGYGSAIGSAVGAFIFGMTSKGIVYAEWNPDWFKFFLGAMLLLATLLN
                     AWVRKRAEATT"
     gene            5184..6038
                     /locus_tag="DBP20_RS30165"
                     /old_locus_tag="DBP20_30185"
     CDS             5184..6038
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491481.1"
                     /locus_tag="DBP20_RS30165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30185"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_109180668.1"
                     /transl_table=11
                     /translation="MTATSETSDKTAGPLVELDDVSKFYGNIKALEHVSLEVHAGEITC
                     VLGDNGAGKSTLIKIIAGLHGHDAGRFLIEGEETTLANPRDALDRGIATVYQDLAVVPL
                     MPVWRNFFLGSEPTTGVGPFKRLDVRKMRETTRTELLRMGIDLRDVDQPIGTLSGGERQ
                     CVAIARAVYFGAKVLVLDEPTAALGVKQSGVVLKYVAAARDAGLGVVLITHNPHHAHLV
                     GDRFVLLKRGVMSGSHTKDDITLDELTRQMAGGSELEELSHELERTPAPILPGTSAATE
                     EGS"
     gene            6173..7339
                     /locus_tag="DBP20_RS30170"
                     /old_locus_tag="DBP20_30190"
     CDS             6173..7339
                     /EC_number="2.7.1.2"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965308.1"
                     /locus_tag="DBP20_RS30170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30190"
                     /product="ROK family glucokinase"
                     /protein_id="WP_030814486.1"
                     /transl_table=11
                     /translation="MSTYRDFAHRGSARATVLRTVGTKERRSHLSAPRVPTVGIDIGGT
                     KVMAGVVDADGNILEKVRTETPDKSKSPKVVEDTIVELVLDLSDRHDVHAVGIGAAGWV
                     DADRSKVLFAPHLAWRDEPLRDAIASRLVVPVMVDNDANTAAWAEWRFGAGRGEDHLVM
                     ITLGTGIGGAILEDGQVKRGKYGVAGEFGHMQVVPSGHRCPCGNRGCWEQYSSGNALVR
                     EAKELAAADSPVAHYLLDRVKGNVSDITGPLITELAREGDAMCIELLQDIGQWLGIGIA
                     NLAAALDPSCFVIGGGVSAADDLLINPARDAFKRHLTGRGYRPEARIAKAQLGPEAGMV
                     GAADLARLVARRFRRTNRRRVERYERYAQIYDQAASTIRNTRSTRTAD"
     gene            7414..8010
                     /locus_tag="DBP20_RS30175"
                     /old_locus_tag="DBP20_30195"
     CDS             7414..8010
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612389.1"
                     /locus_tag="DBP20_RS30175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30195"
                     /product="hypothetical protein"
                     /protein_id="WP_093443943.1"
                     /transl_table=11
                     /translation="MIAAEHPVVPHQSESPGDGEGRPPEDRRRVFKRRFITATIIVLLI
                     GIPAGYLLISAGQSRRSGMDKETEAAAQGLREGWPSKMQRRIFEIPVPGNGQGVQYYET
                     NNWKASRLYVKFRTTSAGLDRFLTGVGTGRAALEPDRISISPRDIKITGWSFGPGEHWA
                     GTTHSNKKPRPTQNITVNMTDPASPVVYVVSAATP"
     gene            8508..9920
                     /locus_tag="DBP20_RS30180"
                     /old_locus_tag="DBP20_30200"
     CDS             8508..9920
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965306.1"
                     /locus_tag="DBP20_RS30180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30200"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_032775386.1"
                     /transl_table=11
                     /translation="MTVESSPEARLEVPRQSSLGTAAARNLASTTKSAPQMQEITSRWL
                     LRMLPWVETKGGAYRVNRRLSFTVGDGRVEFVQDGATIRVIPQELGELAPLRDFDDIEV
                     LTAIADRCVQRDFRAGETLVERGAAADQLHLVAHGRIGQTSVGSYGDEVTLDVLADGDH
                     FGEHVLLDDDARWAHTATAETAGTLLTLSRADFEAIVSSSAELRAHLAEFTARSRQRQN
                     HRGEAEIAMSAGHVGEHELPGAFADYELRPREYELSVAQTILRVHTRVADLYNGPMNQT
                     EEQLRLTIEALRERQEHELINNRDFGLLHNADFKQRIQPHSGPPTPDDLDELLCRRRGT
                     KFFLAHPRTIAAMGREFNARGLYPDHTDLGGQQVPAWRGVPILPCGKIPITPEKTSSIL
                     AMRTGEENQGVIGLRQTGLPDEYEPGLSVRFMGIDDKAIISYLVSTYYSAAILVPDAVG
                     VLENVQIAHWPR"
     gene            10001..11311
                     /locus_tag="DBP20_RS30185"
                     /old_locus_tag="DBP20_30205"
     CDS             10001..11311
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378420.1"
                     /locus_tag="DBP20_RS30185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30205"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_109180669.1"
                     /sec_met_domain="T1TS (E-value: 3.4e-65, bitscore: 219.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVPDLPLPRSSLPEALSRFGATAGAAVAACAPGLGAAAGAPSEA
                     AATPPSVGLPPGPSPVVPPQAGGTEAAWTGRAGGLERLLSGPHGLGTAGLRLTPREEPP
                     APAAAERGRPVPGLYHHPIPEPDPVRVEEVSRRIKDWALDEVSLYPEEWEEQFDGFSVG
                     RYMVGCHPDAPTVDHLMLATRLMVAENAVDDCYCEDHGGSPIGLGERLLLAHTALDPLY
                     TAREYQPDWSASLHADAPRRAYRSAMDYFVRAAAPSQADRLRHDMARLHLGYLAEAAWA
                     QQDQVPEVWEYLAMRQFNNFRPCPTITDTVGGYELPADLHARADMQKVIALASNATTIV
                     NDLYSYTKELDAPGRHLNLPVVIAEREGLSDKDAYLKSVEIHNELMRDFETEAAALALS
                     CPLPGAQRFLRGVAAWVDGNHHWHQSNTYRYSLPDFW"
     gene            11329..12213
                     /locus_tag="DBP20_RS30190"
                     /old_locus_tag="DBP20_30210"
     CDS             11329..12213
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512513.1"
                     /locus_tag="DBP20_RS30190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30210"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_109180670.1"
                     /transl_table=11
                     /translation="MTSAELTATAPAALHIPGPATPYQGDIARYWDGEARPVNLRLGDV
                     DGLYHHHYGVGEVDTAALGDPEDRGYEDRLIAELHRLESAQADVLLGHLGTIGRDDTVV
                     DAGCGRGGSMVMAHQRFGCSVEGVTLSAKQADFANGRAAELGIDGHVRATVCNMLSMPF
                     ATGSAAASWNNESSMYVDLGDLFAEHARVLEVGGRYVTVTGCWNPRYGQPSKWVSQINA
                     HFECNIHSRREYLRAMADNRLVPQAVIDLTPDTLPYWELRATSSLVTGIEDAFINSYRD
                     GSFQYVLIAADRV"
     gene            12487..13776
                     /locus_tag="DBP20_RS30195"
                     /old_locus_tag="DBP20_30215"
     CDS             12487..13776
                     /NRPS_PKS="Domain: Abhydrolase_1 (19-129). E-value:
                     1.2e-21. Score: 69.4. Matches aSDomain:
                     nrpspksdomains_DBP20_RS30195_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965293.1"
                     /locus_tag="DBP20_RS30195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30215"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_109180671.1"
                     /sec_met_domain="PF00561 (E-value: 6.2e-16, bitscore: 57.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9.3e-14, bitscore:
                     51.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDTPRNTLKYCVDGPEDAPVLVIGPSLGTTWHMWDRQIPELSQH
                     WRVFRYDLPGHGGAPAHAAASVAELGDRLLATLDGLGVQRFGYAGCSIGGAIGADLALR
                     HPHRVASLALVASSPRFGTADEFRQRGVIVRTNGLEPMARTAPERWFTPGFAAAQPAIV
                     EWAVQMVRTTDPGCYIAACEALAAFDIRGALGRIGVPTLVLVGAEDQVTGPAEARTLVA
                     GIPDARLALVPGASHLAPVEQPAAVSDLLLMHFSTAWQQDTSAAIPVLPHVTAPAANAV
                     PFVPVAEIAPAATASDAVAPTPDDRYEQGTKVRREVLGDAHVDAVNETADAFTEDFQEL
                     VTRYTWGEVWSRDGLDRRTRSVITITALVASGHLDGLAAHTRAALRNGLTPAEIKEVLL
                     QTAVYCGIPAAGAAFAVAQKVIQEETTPPA"
     aSDomain        12544..12873
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DBP20_RS30195_Abhydrolase_1.1"
                     /evalue="1.20E-21"
                     /label="DBP20_RS30195_Abhydrolase_1.1"
                     /locus_tag="DBP20_RS30195"
                     /protein_end="129"
                     /protein_start="19"
                     /score="69.4"
                     /tool="antismash"
                     /translation="PVLVIGPSLGTTWHMWDRQIPELSQHWRVFRYDLPGHGGAPAHAA
                     ASVAELGDRLLATLDGLGVQRFGYAGCSIGGAIGADLALRHPHRVASLALVASSPRFGT
                     ADEFRQ"
     gene            13789..14442
                     /locus_tag="DBP20_RS30200"
                     /old_locus_tag="DBP20_30220"
     CDS             13789..14442
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965292.1"
                     /locus_tag="DBP20_RS30200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30220"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_109180672.1"
                     /transl_table=11
                     /translation="MNASPGALTLTKKTHSCVRIEKEGRTLVIDPGGFSEDDAALGADV
                     MLVTHEHPDHFNEARLRAGLEANPAAEIWTLRSVAEQLSAAFPGRVHTVGDGDAFSAAG
                     FDVTVHGELHAVIHPDIPRITNVGFLVDGSVFHPGDALTVPERPVDTLLLPVMAPWSKI
                     SEVIDYVREVKPRRAIDVHDALLTDLARPIYDNQIGALGGADHGRLAPGGTTEL"
     gene            14485..15264
                     /locus_tag="DBP20_RS30205"
                     /old_locus_tag="DBP20_30225"
     CDS             14485..15264
                     /EC_number="3.1.11.2"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961423.1"
                     /locus_tag="DBP20_RS30205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30225"
                     /product="exodeoxyribonuclease III"
                     /protein_id="WP_109180673.1"
                     /transl_table=11
                     /translation="MRIATYNVNSITARLPRLLAWLESSGTDVLCIQETKCTAEQFPAE
                     ALREAGYESAVNATGRWNGVALLSRVGLADVVTGLPGGPEYDGVQEPRAISATCGPLRL
                     WSVYVPNGREVEHEHYAYKLRWLEALRKAVAADTAGSLPFAVLGDFNVAPTDEDVWDPA
                     LFEGATHVTPAERAALAALEAEGLSEVHPRPLKYDRAYTFWDYRELRFPKNKGMRIDLT
                     FGNAPFTAAVKDSYVDREERKGKGASDHAPVVVDLDL"
     gene            15343..16089
                     /locus_tag="DBP20_RS30210"
                     /old_locus_tag="DBP20_30230"
     CDS             15343..16089
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072639.1"
                     /locus_tag="DBP20_RS30210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30230"
                     /product="Clp protease N-terminal domain-containing
                     protein"
                     /protein_id="WP_109180674.1"
                     /transl_table=11
                     /translation="MTQPLPVTPSVRLDDLIEAIKKTNGDALEQLSGAVLAADHLGDVA
                     DHLIGHFVDQARRSGASWTDIGRSMGVTRQAAQKRFVPKKGEGSSDLDPNEGFNRFTPR
                     ARNVVVASHNEAQAARHAEIVPAHLILGLLAEPEAVAARVLVGQGVEPDVLRAAATAAL
                     PAPVDEAPELIPYDADAKKVLELTFREALRLGHNYVGTEHILLALLEFEDGSGVLSGLG
                     LDKEAVSAAVERAVGEAAGVLRQQKP"
     gene            complement(16126..16905)
                     /locus_tag="DBP20_RS30215"
                     /old_locus_tag="DBP20_30235"
     CDS             complement(16126..16905)
                     /NRPS_PKS="Domain: PKS_KR (16-130). E-value: 5e-11. Score:
                     34.8. Matches aSDomain:
                     nrpspksdomains_DBP20_RS30215_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128628.1"
                     /locus_tag="DBP20_RS30215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30235"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_109180675.1"
                     /sec_met_domain="adh_short (E-value: 1.1e-29, bitscore:
                     102.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAQTYIAELFSLEGRVAVVTGGSSGIGRAITGALARAGASVVVV
                     ARREAELRETVDELTGEGCRASWVSADLSTAEGVRVGAEEAAAAFGEPDILVNCAGINL
                     RPPMTELGEDVWDTTMAVNLKAPFLLGQRFGPGMAERGYGRIIHVTSQQAHRAFVSSGA
                     YGVSKGGLESLTRSQAEAWSSHGVTVNSLVPGFVLTPLNARLQSDPEKVASLAARTMVG
                     RNGLAEDFAGAAVFLAGRSSAYVTGQSVFVDGGFSVH"
     aSDomain        complement(16516..16857)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DBP20_RS30215_PKS_KR.1"
                     /evalue="5.00E-11"
                     /label="DBP20_RS30215_PKS_KR.1"
                     /locus_tag="DBP20_RS30215"
                     /protein_end="130"
                     /protein_start="16"
                     /score="34.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAVVTGGSSGIGRAITGALARAGASVVVVARREAELRETVDELTG
                     EGCRASWVSADLSTAEGVRVGAEEAAAAFGEPDILVNCAGINLRPPMTELGEDVWDTTM
                     AVNLKAPFLL"
     CDS_motif       complement(16762..16851)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DBP20_RS30215_0001"
                     /evalue="4.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="DBP20_RS30215"
                     /protein_end="48"
                     /protein_start="18"
                     /score="16.0"
                     /tool="antismash"
                     /translation="VVTGGSSGIGRAITGALARAGASVVVVARR"
     gene            17015..17455
                     /locus_tag="DBP20_RS30220"
                     /old_locus_tag="DBP20_30240"
     CDS             17015..17455
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128629.1"
                     /locus_tag="DBP20_RS30220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30240"
                     /product="DUF6278 family protein"
                     /protein_id="WP_032767886.1"
                     /transl_table=11
                     /translation="MNIPFLDNWRKRQGGTQSGTLAAAVETDPDGVAELLAECELLRVR
                     AGQQGLELDDTPASLAALDQLPPRWRDDPEELPWLGNDAGLYLGTVIVRTVPGAAWDIW
                     PSGQPVVRLESGREIDVVSAGLDWAMAGSPELSQVYAESAEN"
     misc_feature    17016..17030
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.26"
                     /tool="antismash"
     gene            17601..18344
                     /locus_tag="DBP20_RS30225"
                     /old_locus_tag="DBP20_30245"
     CDS             17601..18344
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006377699.1"
                     /locus_tag="DBP20_RS30225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30245"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_032775401.1"
                     /transl_table=11
                     /translation="MAVDPLIELRDVNKHFGELHVLQDINLTVGRGEVVVVIGPSGSGK
                     STLCRAINRLETIESGSITIDGRPLPEEGKGLAQLRAEVGMVFQSFNLFAHKTVLDNVS
                     LAQLKVRKRKKDEADRRSRELLERVGLAAHADKFPAQLSGGQQQRVAIARALAMDPKAL
                     LFDEPTSALDPEMINEVLEVMQQLARDGMTMIVVTHEMGFARSAANRVVFMADGCVVED
                     RVPEDFFTSPSSDRAKDFLSKILKH"
     misc_feature    complement(17635..17644)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     gene            18356..19285
                     /locus_tag="DBP20_RS30230"
                     /old_locus_tag="DBP20_30250"
     CDS             18356..19285
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010064069.1"
                     /locus_tag="DBP20_RS30230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30250"
                     /product="glutamate ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_093443929.1"
                     /transl_table=11
                     /translation="MLRTRNTRTGRAAALVAGLLLAALAAGCGKDGSPPVKGPKAEALP
                     VYQVDTGFELPDSRTWTKAKRRGYLIVGAKEDQPYLGEKDPASGIYSGFDIEIARMMAA
                     SLGFEPKTIRFRTIASANRETALQNGQIDYYVGTYTINDMRKKLVGFAGPYYMAGQGLL
                     VRTDEDDIKGPQDLAGKTVCSAAGSTPYQRIAADYPKATLVAYDTYSICVDNLLTYQVD
                     AVTTDDAILLGFAAKAPEEMKVVGKPFSEEPYGIGVPRSDNALRNALNDALEANERDGN
                     WKKAYDATLGLSGAPAPTPPPIDRYPAT"
     gene            19303..19947
                     /locus_tag="DBP20_RS30235"
                     /old_locus_tag="DBP20_30255"
     CDS             19303..19947
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019764397.1"
                     /locus_tag="DBP20_RS30235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30255"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_006128632.1"
                     /transl_table=11
                     /translation="MDVLTENFSLYGKGFLGTVELTVYASALALVLGFLMASFRVAPVG
                     SFRVLGTVWVTVLRNTPLTLLFFAVLLGLPRFGLVLPFQLFAVIALGCYTSAFICEVLR
                     SGINTVPKGQGEAARSLGMNFGQTLSTVVLPQAFRSVIPPVGSTLIALAKNSAIAGAFS
                     VTELLGTYKTLNELGYSIIWSFIWIAVGYLIITLTISAVFNVMEKRWGVAR"
     gene            19944..20840
                     /locus_tag="DBP20_RS30240"
                     /old_locus_tag="DBP20_30260"
     CDS             19944..20840
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961430.1"
                     /locus_tag="DBP20_RS30240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_30260"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_093443927.1"
                     /transl_table=11
                     /translation="MTKTLTRKASRASAPEATALYDIPGPVTRRRHLMYGIASTVVILA
                     LFGWIVYLLFDTDQFTAEKWTPFEYKGIQELLLRGLGNTLKAFAYAAVLSLALGAVLAV
                     GRLSEHRVLRWISTLLVEFFRAMPVLVMIFFIFVALKVQPLPALVAGLTLYNGSVLAEV
                     FRTGINAVDRGQREAAYALGMRKTQVTTYVLAPQAVRAMLPTIISQLVVALKDTSLGYL
                     ITYEEFLHAGKLIASNLDYDLPFIPVVMVISPIYIGMCMLLSWFATWVAKRQRRNLKTR
                     AVGVAPAEPGTLLPGGQ"
     misc_feature    complement(20880..20893)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.87"
                     /tool="antismash"
     misc_feature    21271..21286
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.6"
                     /tool="antismash"
ORIGIN
        1 gccacgcata caggagatga ccgacgagct gctggacgcc atgctcgcgg ctccggaccg
       61 ctcggccgac ctcgtcgagg cgctgtcctt cccgctgccc atgtcggtca tctgcgagct
      121 gctcggcgtg ccgttcctgg accgcgagga cttccgcacc tggtccggcc aggcggtctc
      181 ctccctcgac gcgtccctgc gtgcctcctc cacccaggcg atgaccgcgt acatcgccgg
      241 tctgctggcc gacaagcgcg agaatccggg cggcgacctg ctgagcgcgc tgatccacac
      301 cgccgacgag gacggcgacc ggctgtccgg cgaggaactg atcggcatgg cctggctgtt
      361 gctcgtcgcc ggacacgaga cgaccgtcaa cctcatcacc aacggcgtcc acaacctgct
      421 cgcacacccg ggtcaactgg ccgccctgcg tgcggacttc tccctcatcg acaacgccgt
      481 cgaggagatc ctgcgcttcg aggggccggt ggagaccccc acgtaccgct tcaccaccga
      541 gccgatcgag gtgggcggca cggtgatccc cggcggcggc gaactggtcc tggtcgcgat
      601 gtcggacgcc aaccgggacc ccgaccgcta ccccggcggg gaccgcttcg acatcacccg
      661 ggacgcccgg ggccacatcg ccttcgggca cggcatccac tactgcctgg gcgccccgct
      721 ggcccgtatc gaggcccgta ccgccatccg gtcgctactg gagcgctgcc cggacctgcg
      781 gctgaccgcc gacccggcga cgctgacctg gcgcaccgga atgctgatga ggggcccgct
      841 gagcctgccc gtcgcctggt agcggcgggc aggcttccgg ctcccggttc tcgggcttcc
      901 gtcagccgcc ggggatctcg tccatcgcca ccggccggcg ttcgcggcgg gagacctcgc
      961 atgcctcggc gatccgcagg gcgtgcaggg cctcccgccc gtcgcacgga ttggccagct
     1021 cgccgcggac cacgcgcagg aacgcgtcca gctccgcctc gtacgccggg gcgaaccgtt
     1081 ccaggaagcc cggccagggc ttcgccgggg cgccggggcc gccgggctcg gccgaggtca
     1141 gcggcgtacg gtcgtcgagg ccgacggcga tctggtccag ttcgccggcc agctccatcc
     1201 gtacgtcgta cccggcgccg ttgcaccggg tcgcggtggc ggtggcgagc gtcccgtcgt
     1261 cgagggtgag cagggccgcg gccgtgtcca cgtccccggc ctcccggaac atcgcgggcc
     1321 ccgtgtccga tccggtggcg tacacctcgc tcacctcgcg gcccgtcacc cagcgcagga
     1381 tgtcgaagtc gtggaccagg cagtcacggt acagcccgcc ggagagcggg aggtaggcgg
     1441 cgggcggcgg cgcgggatcg gaggtgaccg cccgcacggt gtgcagccgg cccagccgcc
     1501 cgtcccgcac ggcggccctg gcctcgccgt acccggcgtc gaagcgccgc atgaagccga
     1561 gctggagcaa actccccgcc gcctcgacct cggccagcgc ggcgagcgtg ccgggcaggt
     1621 ccagggcgat cggcttctcg cagaaggcgg gcagcccggc gcgggcggcg cgggcgatga
     1681 gcccggcgtg cgcggcggtc gccgaacaga tgaccacggc gtcgggcggg gccggcgcct
     1741 cgtccgcccc gctgaagagg tcgtccacgg cgacggccgt ccccccggtc cgcagggccg
     1801 aggcggcagc ccgttccgga tccgcgtccg ccagcagcag ggcgtccacg gcggggtgac
     1861 ggctcagcac ctccgcatgg aatgtgccga tccgtcccgt tccgatcagt ccgatgcgca
     1921 tgggccccaa ggtggcttcg cccggtcgtc atgtcaagcg tttgtcctga caaacgacag
     1981 gccatggcta tgtccggaca agcgaactac gctcgccccg tgaccgcaca tggaaccgac
     2041 cggccgctgc cgctgagcgt ggaccgcacc agcccggtgc cgctctactt ccagctggcg
     2101 cagcagctgg aggcggccgt ggagcagggc cggctggccc ccggcgccct gctcgggaac
     2161 gagatcgacc tggcctcccg gctgggcctg tcccgcccga ccgtccgcca ggccatccag
     2221 acgctcgtcg acaaggggct gatggtgcgc cggagggggg tcggcaccca ggtcgtccac
     2281 agccaggtcc gccgcccgct ggagctcagc tcgctctacg acgacctgga ggcggcgggc
     2341 cagcgccccg ccaccgctgt cctgcgcaac acgacggaac cggccacggc cgaggtcgcc
     2401 gccgcgctcg gggtcgccga gggcagcgag gtccatctcg tggagcggct gcgcagcgcg
     2461 cacggcgaac cgatggcgct cctgcgcaac cacctgccgc cggggctggt gcccctgcgc
     2521 accgacgagc tggaggccac cggcctctac cggctgatgc gcgccgccgg catcacgctg
     2581 cacagcgccc gccagacggt gggcgcgcgc gccgcgacgg tgggggaggc gcgggacctg
     2641 gacgaggagc cgggggcgcc gctgctgacg atggaacgcg tgacgtacga cgacacgggg
     2701 cgggtggtgg agttcgggtc ccacgtctac cgcgcggcgc gctacgcctt cgagttccag
     2761 ctcctggtcc gcccgtagcc caccccagcc cgtccggagt tcgaggacgg aacccttgcg
     2821 gtggtgtcgg ccgcgcctgc gaggttcctg ggccccaggc ccctgtggtc tgcgggcccg
     2881 cccgcccgag ggttccgtcc tcgatcgccg gacgggcttg aaggcgcggg cccgcccagg
     2941 cccgcggggc ggcggaaaag gtccaggcac acgggttgcg ctcggccgcc ccgtgcccca
     3001 ggctcctgtg accgtcggcc acccgcacaa ggccccgggg cagggctcgg ggatactggg
     3061 cagccggccc gggaccgcac acccccggcc aggtcaggcg aagcgcacag cagaagaagg
     3121 gcacggtgtc gtggcaaggg ttcggacagg ggtacgcgca ctgggcgccg tgctggcagt
     3181 gatgctggca gccgcgggat gcagcagcac cggcggcaag cgggcggaag aacgcgcggc
     3241 cgaggccgcc gaggggcggg ccgcggtgaa caccccccgc tggaccttcg ccatggtcac
     3301 ccactcggga gacggcgaca cgttctggga catcgtccag aagggcgccg agcaggcggc
     3361 cctcaaggac aacatcaact tcctctactc gcacaacgac gaggccaacc agcaggccca
     3421 gctcgtccag accgcgatcg acaagaaggt cgacggcctg atcgtctcgc tggccaagcc
     3481 ggacgcgatg aaggccgtgg tcgccaaggc cgtcaaggcc ggcatccccg tcgtcaccgt
     3541 gaactccggc tccgccgagt cgaaggagtt cggcgcgctc acccacatcg gccaggacga
     3601 gaccatcgcc ggtgaggccg tcggcgacga gctgaacaac cgggaccgca agaaggcgct
     3661 gtgcgtcctg cacgagcagg gcaacgtggg ccacgagcag cgctgcgccg gagcgaagaa
     3721 gaccttcgac ggcacgatgc agaacctgta cgtcgacggc accaacatgc ccgacgtcac
     3781 cgcgtccatc gaggccaagc tccagtccga caagagcatc gacgcggtcg tcaccctcgg
     3841 cgcccccttc gccgacgcgg ccgtccaggc caagcagacg gcgggcagca aggccgagat
     3901 cgacaccttc gacctcaacg ccaaggtcgc cgccggcctc cagaccgaca agctcggctt
     3961 cgccgtcgac cagcagccct acctccaggg gtacgaggcc gtcgacctgc tctggctcta
     4021 ccgctacaac cgcaacgtgc tcggcggcgg ccagcccgtc ctgaccggcc cccaggtcat
     4081 caccaaggac gacgccgacg ccctggccga ctacaccaag cggggcaccc gatgagcggc
     4141 tccaccgccg ccccggagaa gcccgcgcag ctcgacgagc gcctcgtcca cacctcgccg
     4201 ctgcgcaagc tgctcggccg ccccgagctg ggctcggtgg tcggcgcggt cgccgtcttc
     4261 ctgttcttcg cgatcgtcgc cgacagcttc ctccaggcgt ccagcttcgg caccgtcctg
     4321 tacgcggcct cggtgctcgg catcatggcc gccccggtgg ccctgctgat gatcggcggc
     4381 gagttcgacc tctccgcggg cgtcctggtg accagctccg cgctgatctc gtcgatgttc
     4441 agctaccaga tgacggccaa cgtctgggtc ggcgtcctgg tgtccctgct ggtcacgctc
     4501 gccatcggcg cgttcaacgg cttcatgctg acccgcaccg aactgccgag cttcatcatc
     4561 acgctcggca cgttcctgat gctgaccggt ctgaacctcg gcttcaccaa gctcatcagc
     4621 ggcaccgtct ccaccaaggc gatcggcgac atggagggct tcgactcggc ccacgccctg
     4681 ttcgcctcca cgctgaccgt cggcagcgtc gagttcaagg tgaccatcct gtggtggatc
     4741 gccctcgtcg ccgtcgccac ctggatcctg ctccgtaccc gcttcggcaa ctggatcttc
     4801 gcggtcggcg gtcaggccga cgcggcccgc gcggtcggcg tcccggtcgt ccgcaccaag
     4861 atcggcctct acctcggcgt cgccttcgcc gcctggatct ccggccagca cctgctgttc
     4921 agctacgacg tcgtccagtc cggcgagggc gtcggcaacg agctgacgta catcatcgcc
     4981 gccgtcatcg gcggctgcct gatcaccggc ggctacggct ccgcgatcgg ctcggcggtc
     5041 ggcgccttca tcttcggcat gaccagcaag ggcatcgtct acgccgagtg gaacccggac
     5101 tggttcaaat tcttcctggg agcgatgctg ctcctggcca ccctgctcaa cgcgtgggtg
     5161 cgcaagcgcg cggaggcgac gacatgacgg ccacgtccga gacgtccgac aagaccgccg
     5221 gccccctcgt cgagctggac gacgtgtcca agttctacgg caacatcaag gccctggaac
     5281 acgtctcgct ggaggttcac gcgggcgaga tcacctgcgt cctcggcgac aacggcgctg
     5341 gcaagtccac cctcatcaag atcatcgcag ggctgcacgg acacgacgcc ggacgctttc
     5401 tgatcgaggg cgaggagacg accctcgcca acccgcgcga cgccctggac cggggcatcg
     5461 ccaccgtcta ccaggacctc gccgtcgtcc cgctgatgcc ggtctggcgg aacttcttcc
     5521 tcggctccga gcccacgacc ggcgtcggcc ccttcaagcg cctcgacgtc cggaagatgc
     5581 gcgagacgac ccgtacggaa ctgcttcgca tgggcatcga cctgcgcgac gtcgaccagc
     5641 ccatcggcac cctgtccggc ggcgagcgcc agtgcgtggc catcgcccgc gccgtctact
     5701 tcggcgccaa ggtcctcgtc ctggacgagc cgaccgccgc gctcggcgtc aagcagtccg
     5761 gggtggtcct caagtacgtg gcggccgccc gcgacgccgg cctcggcgtg gtcctcatca
     5821 cgcacaaccc gcaccacgcc cacctcgtcg gcgaccggtt cgtcctcctc aagcgcggag
     5881 tgatgtccgg cagccacacc aaggacgaca tcacgctcga cgagctgacc cggcagatgg
     5941 cgggcggcag cgagctggag gagctcagcc acgagctgga acgcactccc gcgcccatcc
     6001 tcccgggcac gtccgcggcg accgaagaag gatcctgacc gacgacccgt cccggcgcgg
     6061 ccgaccccgc ccatcggccc gccggggccg ggcagtggca gaatcgagcc cggcgggcgc
     6121 cgtccgccgc cggccgcgac agcggcccgg ccccccagac cccgcaggga cgatgagcac
     6181 gtaccgcgac ttcgcccacc gcggctccgc ccgcgccacc gtcctcagga cggtcggcac
     6241 caaggaacgc cgctcgcacc tgtccgcgcc ccgcgtcccc acggtcggga tcgacatcgg
     6301 cggtacgaag gtgatggcgg gcgtcgtcga cgccgacggc aacatcctgg agaaggtccg
     6361 caccgagacg cccgacaagt ccaagagccc caaggtcgtc gaggacacca tcgtcgagct
     6421 ggtgctggac ctctccgacc ggcacgacgt ccacgcggtg ggcatcggcg cggcgggctg
     6481 ggtcgacgcc gaccgctcca aggtcctctt cgccccgcac ctcgcctggc gcgacgagcc
     6541 cctgcgcgac gccatcgcct cccggctcgt cgtccccgtc atggtcgaca acgacgccaa
     6601 caccgccgcc tgggcggaat ggcgcttcgg cgcgggccgc ggcgaggacc acctcgtcat
     6661 gatcaccctc ggtacgggca tcggcggcgc gatcctggag gacggccagg tcaagcgcgg
     6721 caagtacggc gtggccggtg agttcggcca catgcaggtc gtcccttcgg ggcaccgctg
     6781 cccctgcggc aaccgcggct gctgggagca gtacagctcc ggcaacgccc tcgtccgcga
     6841 ggccaaggag ctggccgccg ccgactcccc ggtcgcccac tacctgctgg accgggtgaa
     6901 ggggaacgtc tccgacatca ccgggccgct catcaccgaa ctggcccgcg agggcgatgc
     6961 gatgtgcatc gaactcctcc aggacatcgg ccagtggctc ggcatcggca tcgccaatct
     7021 ggccgccgcg ctcgacccct cctgcttcgt catcggaggc ggcgtcagcg ccgccgacga
     7081 cctcctgatc aaccccgccc gggacgcctt caagcgccat ctcaccggcc gcggctaccg
     7141 ccccgaggcc aggatcgcca aggcgcagct gggccccgag gcgggtatgg tcggcgccgc
     7201 ggacctggcg cggctggtcg cccgccgctt ccgccggacc aaccggcggc gcgtcgagcg
     7261 gtacgagcgc tacgcccaga tctacgacca ggcggcgagc accatccgca acacgcggtc
     7321 cacccgtacc gccgactgaa ccgcgaccgc cctttccggc gtccacccct ccgtacgcct
     7381 cacgtcgccg cagcacctag ggaccacctg atcatgatcg cagccgagca ccccgtggtg
     7441 ccgcaccagt cggagtctcc gggcgacggc gagggcagac cgcccgagga ccgccggcgg
     7501 gtgttcaagc ggcgcttcat caccgccacg atcatcgtgc tgctgatcgg catcccggcc
     7561 ggctacctgc tgatctcggc cggccagagc cgccgctcgg gcatggacaa ggagaccgag
     7621 gcggccgccc aggggctgcg cgagggctgg ccctccaaga tgcagcgccg gatcttcgag
     7681 atcccggtcc ccggcaacgg acagggcgtt cagtactacg agacgaacaa ctggaaggcc
     7741 agccggctgt acgtgaagtt ccgtaccacc tccgccggtc tcgaccgctt cctgaccggg
     7801 gtgggcaccg gacgtgcggc gctggagccc gacaggatct ccatcagccc gcgggacatc
     7861 aagatcaccg gctggtcctt cggcccaggc gagcactggg ccggcaccac gcacagcaac
     7921 aagaagccgc gccccaccca gaacatcacg gtcaacatga ccgatccggc cagccccgtc
     7981 gtctatgtcg tatcggcggc gaccccctga ccgtgagccc gtgtggcgac ccttgggcgt
     8041 gagcccgtga gcgcgtgagc ccgtgaggcg ccccccacgc ggagcctgag cgagtcggcc
     8101 ccggcggata tctcacccgc cggggccgac gcgcgtgtgt gcgtggccgc tctccgcagc
     8161 cgccctaccc tgtcccgctc ggcactgcca ccgcctgccc gcccaggcag gccggatttc
     8221 gtcgcgcatg ggccgttgtg ggctccccgc agcccgggac gcctgccgga cggccctcgc
     8281 aagcacggct gaaatccgtc caacgcggcc aaacgttcct cgggcgcgat catcgtatcg
     8341 agctaacgtc ggtggatttc cttggtccga acggtggcgg ggcccttagt gttcccctgg
     8401 atctgaaggg ggttcatctc cttatcggat ctttcctccg cattcccacc cctacgaccg
     8461 ttcgcgtcgc atgcgcgcgt cccgcccgac caaggagagc ctgcccgatg actgttgaat
     8521 cgagcccgga agcccggctg gaagtgcccc ggcagtccag cctggggacg gccgcggccc
     8581 gcaacctcgc cagcacgacg aagtccgccc cgcagatgca ggagatcacc tcccgctggc
     8641 tgctgcggat gctcccgtgg gtcgagacca agggcggtgc ctaccgggtc aaccgacgtc
     8701 tctccttcac ggtgggtgac ggacgggtgg agttcgtcca ggacggggcc acgatccggg
     8761 tcatccccca ggagctgggc gaactcgccc cgctgcggga cttcgacgac atcgaggtcc
     8821 tgaccgccat cgccgaccgg tgtgtccagc gtgacttccg ggcgggggag acgctggtcg
     8881 agcgaggcgc ggccgcggac cagctccacc tcgtcgcgca cggccggatc ggccagacct
     8941 ccgtcggcag ctacggcgac gaggtcaccc tggacgtcct ggcggacggg gaccacttcg
     9001 gcgagcacgt cctgctggac gacgacgccc ggtgggcgca caccgccacc gccgagaccg
     9061 cgggcaccct gctcacgctc tcccgcgcgg acttcgaggc catcgtgtcg agctcggccg
     9121 agctccgggc ccacctcgcc gagttcaccg cacgctcccg gcagcggcag aaccaccgcg
     9181 gtgaggcgga gatcgcgatg tcggccggcc acgtcggcga gcacgagctg cccggcgcct
     9241 tcgccgacta cgagctgcgc ccgcgcgagt acgaactctc ggtggcccag accatcctgc
     9301 gggtccacac cagggtcgcc gacctctaca acggtccgat gaaccagacc gaggaacagc
     9361 tcaggctcac catcgaggcg ctgcgggaac gccaggagca cgagctgatc aacaaccggg
     9421 acttcggtct gctccacaac gccgacttca agcagcgcat ccagccgcac tccggcccgc
     9481 cgaccccgga cgacctggac gagttgctct gccgccgccg gggcaccaag ttcttcctcg
     9541 cgcacccccg gacgatcgcg gcgatggggc gcgagttcaa cgcgcgcggc ctctacccgg
     9601 accacaccga cctcggtggc cagcaggtcc ccgcctggcg aggcgtcccg atcctgccct
     9661 gcggcaagat ccccatcacc ccggagaaga ccagttcgat cctcgccatg cgtaccggcg
     9721 aggagaacca gggcgtcatc ggtctccggc agaccggact gccggacgag tacgaaccgg
     9781 gcctctcggt gcgcttcatg ggcatcgacg acaaggcgat catctcctac ctcgtcagca
     9841 cctactactc cgccgccatc ctggtgcccg acgcggtcgg cgtgctggag aacgtacaga
     9901 tcgcccactg gcccaggtag cgggcgcggc gcggagcccg gaagcggacc gcgtgcccgg
     9961 acgtcgtcga agaccagccc acctcatcaa ggagccacgc atgcccgtgc ccgacctgcc
    10021 gcttccgcgg tcgagcctgc cggaggccct ctcccgcttc ggggcgaccg cgggcgccgc
    10081 ggtcgcggcc tgcgcccctg gcctcggtgc cgccgccggt gcaccgtccg aagcagccgc
    10141 gacgccccca tcggtcggcc tccccccggg cccttcaccg gtcgtcccac cgcaggccgg
    10201 tgggacggag gccgcgtgga cgggccgggc gggcggcctg gaacggctgt tgagcggacc
    10261 ccacggcctg ggcacggcag gtctgcggct gacaccgcgc gaggagcctc ccgcgccggc
    10321 ggccgcggag cgcggccgac cggttccggg tctctaccac cacccgatcc ccgagcccga
    10381 cccggtgcgg gtcgaggagg tcagccgtcg catcaaggac tgggccctgg acgaggtctc
    10441 cctgtacccc gaggagtggg aggagcagtt cgacggcttc tccgtgggcc ggtacatggt
    10501 cggctgccac ccggacgcgc ccaccgtcga ccacctgatg ctcgccaccc gcctgatggt
    10561 cgccgagaac gccgtggacg actgctactg cgaggaccac ggcgggtcgc ccatcggcct
    10621 cggcgagcgg cttctgctcg cgcacaccgc gctggacccc ctgtacaccg cgcgcgagta
    10681 ccagccggac tggtcggcct cgctccacgc ggacgccccc cggcgcgcct accgctccgc
    10741 catggactac ttcgtccgcg cggcggcacc ctcccaggcg gaccggctcc gccacgacat
    10801 ggcgcgcctg cacctggggt atctcgccga agcggcctgg gcccagcagg accaggtccc
    10861 ggaggtctgg gagtacctgg cgatgcgcca gttcaacaac ttccggccct gccccaccat
    10921 caccgacacc gtcggcggct acgaactccc ggcggatctg cacgcccgcg ccgacatgca
    10981 gaaagtcatc gccctggcct ccaacgcgac gacgatcgtg aacgacctct actcgtacac
    11041 caaggaactc gacgctccgg gccggcacct gaacctgcct gtcgtgatcg ccgaacgcga
    11101 ggggctgtcg gacaaggacg cctacctcaa gtcggtcgag atccacaacg agctgatgcg
    11161 cgacttcgag accgaggccg ccgcactggc cctctcctgt ccccttccgg gcgcacaacg
    11221 cttcctgcga ggcgtcgccg cctgggtcga cggcaaccac cactggcatc agtcgaacac
    11281 ctatcgctac agcctgcccg atttctggta gaagagaagg aaccatctgt gaccagcgcc
    11341 gaactgaccg ccaccgctcc cgccgcactg cacatccccg gcccggcgac cccctaccag
    11401 ggagacatcg cccgctactg ggacggcgag gcccggcccg tgaacctgcg actcggcgac
    11461 gtcgacggcc tctaccacca ccactacggg gtcggcgagg tcgacaccgc cgcgctcggc
    11521 gacccggagg acagggggta cgaggaccga ctgatcgccg agctccaccg cctggagtcc
    11581 gcgcaggcgg acgttctcct cggacacctc ggcaccatcg ggcgtgacga caccgtcgtg
    11641 gacgcgggct gcggccgcgg cggctccatg gtgatggcgc accagcgctt cgggtgctcg
    11701 gtggaaggcg tgaccctgtc ggccaagcag gccgacttcg ccaacgggcg tgccgcggag
    11761 ctgggcatcg acggccacgt ccgtgccacg gtgtgcaaca tgctctccat gcccttcgcg
    11821 accggctccg ccgcggcctc gtggaacaac gagtcgagca tgtacgtcga cctgggcgat
    11881 ctcttcgccg agcacgcccg tgtcctggag gtcggcggcc gctacgtgac cgtcaccggc
    11941 tgctggaacc cgcgctacgg tcagccgtcg aagtgggtct cgcagatcaa cgcgcatttc
    12001 gaatgcaaca tccactcccg ccgggagtac ctgcgcgcca tggcggacaa ccgccttgtg
    12061 ccgcaggccg tgatcgacct cacccccgac accctgccct actgggagct gcgggccacg
    12121 tcctcgctgg tcacggggat cgaggacgcg ttcatcaact cctaccggga cgggtccttc
    12181 cagtacgtcc tcatcgcggc cgaccgcgtc tgacggcacc ggctcagggg cggccgacgc
    12241 cggggatctc ccggtgccgg ccgttctcgc gtcgggcctg aagcggcgcg gccgcggggt
    12301 cgggtcggaa gcagacggtc cgtacagccc ggtcaggccg gaagcagacg gtccgtacat
    12361 cggcacagcc ggacgcgtcg ccgctcgaac cgccggcgcc gaggccggcg gcccgcgagg
    12421 ccggtcgcgc gggacaccgg ccacctgagt tgggggaggc ggtagccgga tgagagggtc
    12481 gagcgggtga gcgacacacc acggaacacc ctcaagtact gcgtcgacgg tcccgaggac
    12541 gccccggtcc tggtcatagg tccctcgctg gggacgacct ggcacatgtg ggaccgccag
    12601 atacccgagt tgtcccagca ctggcgggtc ttccgctacg acctgcccgg ccacggcggc
    12661 gcgcccgccc acgccgccgc ctccgtcgcc gagctgggcg accggctgct cgcgaccctg
    12721 gacgggctcg gcgtccagcg cttcggctac gcgggctgct cgatcggcgg ggcgatcggc
    12781 gcggacctgg ccctgcgcca cccgcaccgg gtcgcctcgc tggccctcgt cgcctcctcg
    12841 ccccggttcg gcacggccga cgagttccgt cagcggggcg tgatcgtccg caccaacggg
    12901 ctggagccga tggcccgcac cgcgcccgaa cggtggttca cccccgggtt cgccgcggcc
    12961 cagcccgcca tcgtggaatg ggccgtgcag atggtccgca ccaccgaccc cggctgctac
    13021 atcgcagcct gcgaggcgct cgcggcgttc gacatccgtg gcgccctggg caggatcggc
    13081 gtccccaccc tcgtgctggt cggggcggag gaccaggtca ccgggcccgc cgaggcccgc
    13141 acgctggtcg ccgggatacc ggacgcccgc ctcgcgctcg tccccggcgc ctcccacctc
    13201 gcgcccgtcg agcagcccgc cgccgtcagc gacctgctgc tgatgcactt ctccaccgcc
    13261 tggcagcagg acacctcggc cgcgatcccc gtgctgcccc acgtcaccgc gcccgccgcc
    13321 aacgccgtgc cgttcgtccc ggtggccgag atcgccccgg ccgccaccgc ctccgacgcc
    13381 gtcgcgccga ccccggacga ccggtacgag cagggcacga aggtccgccg cgaggtgctg
    13441 ggggacgccc atgtcgacgc ggtgaacgag acggccgacg ccttcaccga ggacttccag
    13501 gagctggtca cccggtacac ctggggcgag gtctggagcc gcgacggcct cgaccgccgc
    13561 acccgcagcg tcatcacgat caccgcactc gtcgcctccg gccacctgga tggcctcgcc
    13621 gcgcacaccc gggccgccct gcgcaacggt ctgacgcccg ccgagatcaa ggaagtcctg
    13681 ctccagaccg ccgtctactg cggcatcccg gccgccggag ccgccttcgc cgtggcgcag
    13741 aaggtgatcc aggaggaaac caccccgccc gcgtagcagg atggggccat gaacgcatcg
    13801 cccggggcac tcaccctcac caagaagacc cactcctgcg tccggatcga gaaggagggg
    13861 cgcaccctgg tcatcgatcc cggaggcttc tccgaggacg acgcggcgct cggcgcggac
    13921 gtcatgctgg tgacgcacga gcacccggac cacttcaacg aggcacggct gcgcgcgggc
    13981 ctggaggcca atccggcggc cgagatctgg acgctgcgca gcgtcgccga gcagctctcg
    14041 gccgccttcc cgggccgggt gcacaccgtg ggcgacgggg acgcgttctc cgccgccgga
    14101 ttcgacgtca ccgtgcacgg cgagctccac gcggtcatcc acccggacat cccgaggatc
    14161 accaacgtcg gcttcctggt ggacggttcg gtcttccacc ccggcgacgc gctcaccgtt
    14221 cccgagcgcc ccgtggacac gctgctgctg cccgtgatgg ccccctggag caagatctcc
    14281 gaggtcatcg actacgtacg cgaggtgaag ccgcggcgcg ccatcgacgt ccacgacgcc
    14341 ctgctgaccg atctggcccg cccgatctac gacaaccaga tcggcgccct gggcggcgcg
    14401 gaccacggcc ggctggcccc gggcggcacc accgagctgt gagcccggcg gccgctgtca
    14461 gtgggagcgg ctaggttggc tgccatgcgc atcgccacct ataacgtcaa ttcgatcacc
    14521 gcccggctgc cgaggcttct ggcctggctg gagagcagcg gcaccgatgt gctgtgcatc
    14581 caggagacca agtgcacggc ggagcagttc cccgccgaag ccctgcgcga ggcggggtac
    14641 gaatccgccg tcaacgccac cggccggtgg aacggggtcg cgctgctctc ccgcgtcggc
    14701 ctcgccgacg tcgtcaccgg gctgcccggc ggcccggagt acgacggcgt gcaggagccc
    14761 cgcgcgatct cggcgacctg cggcccgctg cgcctctggt cggtgtacgt gcccaacggc
    14821 cgcgaggtcg agcacgagca ctacgcgtac aagctgcgct ggctggaggc cctgcggaag
    14881 gccgtggcgg cggacaccgc cgggtccctg cccttcgcgg tcctgggcga cttcaacgtg
    14941 gctccgaccg acgaggacgt ctgggacccg gcgctgttcg agggcgccac gcatgtgacg
    15001 cccgccgagc gcgccgccct cgcggccctg gaggcggagg gtctgagcga ggtccacccc
    15061 cgccccctca agtacgaccg cgcctacacc ttctgggact accgcgagct gcggttcccc
    15121 aagaacaagg gcatgcggat cgacctgacc ttcggcaacg cgccgttcac ggccgcggtc
    15181 aaggacagtt acgtcgaccg cgaggagcgc aagggcaagg gcgcgtccga ccacgctccc
    15241 gtggtcgtcg acctcgacct ctgagcaggg cgggcgggag accgcacggc atgtgacaac
    15301 ccaaggttga caccctctcg ggtgtcaacc tacggttgtc gcatgacgca gcctcttccc
    15361 gtcacccctt ccgtacgcct cgacgatctg atcgaggcca tcaagaagac caacggcgac
    15421 gccctggagc agctctccgg cgcggtcctc gccgccgatc acctcggaga cgtggccgac
    15481 cacctcatcg gccacttcgt ggaccaggcc cgccgctccg gcgcctcctg gaccgacatc
    15541 ggacggagca tgggggtcac ccgccaggcc gcccagaagc gcttcgtgcc caagaagggc
    15601 gagggctcat ccgacctcga cccgaacgag ggcttcaacc gcttcacccc gcgcgcccgc
    15661 aacgtggtgg tcgcctccca caacgaggcc caggccgccc ggcacgccga gatcgtcccc
    15721 gcccatctga tcctcggcct gctcgccgag cccgaggccg tcgccgcccg cgtcctcgtc
    15781 gggcagggcg tggagccgga cgtgctgcgg gcggcggcga ccgcggcgct gcccgccccg
    15841 gtggacgagg cgcccgagct gatcccgtac gacgcggacg ccaagaaggt cctggagctg
    15901 accttccgcg aggccctgcg cctcggccac aactacgtcg gcaccgagca catcctgctg
    15961 gccctgctgg agttcgagga cggctccggc gtgctgagcg gcctcggcct cgacaaggag
    16021 gccgtgtccg ccgcggtgga gcgggcggtg ggcgaggcgg ccggggtcct ccggcagcag
    16081 aagccctgag ccccgcggca acccccgtgt ccgtggacgg cggcctcagt gcaccgagaa
    16141 cccgccgtcc acgaacaccg actgcccggt gacgtacgcc gatgagcgcc ccgccaggaa
    16201 caccgcggcc ccggcgaagt cctccgcgag gccgttgcgg ccgaccatcg tccgggccgc
    16261 cagagacgcc accttctccg ggtccgactg gaggcgcgcg ttcagcgggg tcagcacgaa
    16321 cccgggcacc agactgttga ccgtgacgcc gtgcgacgac cacgcctcgg cctgcgagcg
    16381 ggtcagcgac tccagaccgc ccttggacac cccgtaggcg ccactgctca cgaaggcccg
    16441 gtgcgcctgc tgcgacgtca catggatgat ccgcccgtac ccccgctcgg ccatgcccgg
    16501 cccgaaccgc tgccccagca ggaacggtgc cttcaggttc accgccatcg tggtgtccca
    16561 gacgtcctcg cccagctcgg tcatcggcgg gcgcagattg atcccggcgc agttcaccag
    16621 gatgtccggc tccccgaacg ccgccgcggc ctcctccgcc ccgacgcgca ccccctcggc
    16681 ggtgctcagg tccgcgctca cccaggaggc ccggcagccc tccccggtca gctcgtccac
    16741 ggtctcccgc agctccgcct cccggcgggc caccacgacg acactcgcgc cggcccgggc
    16801 cagggcgccg gtgatcgccc ggccgatgcc ggagctgcct ccggtgacca ccgccacccg
    16861 gccctccagt gagaacagtt ccgcgatgta ggtctgtgca ctcatgtacg caccttagat
    16921 atgcgctcgg attcacggcc ggggcggggt gggggaccgg tgaacgccgc gcgccctgtg
    16981 gtgcggaacc tggccgggat gggaccctag tggtatgaac atccctttct tggacaactg
    17041 gcgtaagcgt cagggtggta cgcagtcggg cacgctcgcc gccgccgtcg agacggaccc
    17101 cgacggtgtg gccgagctgc tcgccgaatg cgaactgctg cgcgtccggg cggggcagca
    17161 aggactcgaa ctcgacgaca ccccagcctc gttggccgcg ctcgaccagc tgccgccccg
    17221 ctggcgcgac gaccccgagg aactgccctg gctcggcaac gacgccggcc tctatctcgg
    17281 cacggtgatc gtgcggacgg tgccgggcgc cgcgtgggac atctggccga gcggccagcc
    17341 cgtggtgcgg ctggagtccg gccgggagat cgacgtcgtc tcggccgggc tcgactgggc
    17401 gatggcgggc agtccggagc tctcccaggt gtacgcggag tccgccgaga actgagcggg
    17461 ggccggagag cggccgctct cctcggctaa tccagttaaa aagccttttg cgccatttac
    17521 gcgtgtcggg tgcgaagtcc cttttcgcga tggatagttt gcgctgacct cgacacagcg
    17581 acaagtgggt agggcagcgc atggccgtcg atcctttgat cgaactgagg gacgtcaaca
    17641 aacacttcgg agagttgcac gtacttcagg acatcaatct caccgtcggc cgcggggagg
    17701 tggtggtggt catcggcccc tccggctcgg ggaaatcgac cctgtgccgg gcgatcaacc
    17761 ggctggagac gatcgagtcc ggcagcatca cgatcgatgg cagacccctc cccgaggagg
    17821 gcaagggcct ggcccagctc cgtgccgaag tcggcatggt cttccagtcg ttcaacctct
    17881 tcgcccacaa gaccgtgctg gacaacgtct cgctggcgca gctcaaggtc cgcaagcgca
    17941 agaaggacga ggccgaccgg cgctcccgcg aactgctgga gcgggtcggg ctggccgcgc
    18001 acgccgacaa gttccccgcc cagctctccg gcggccagca gcagcgcgtg gccatcgccc
    18061 gcgccctggc catggacccc aaggcactcc tgttcgacga gccgacctcg gcgctcgacc
    18121 cggagatgat caacgaggtc ctggaggtca tgcagcaact ggcccgggac ggcatgacga
    18181 tgatcgtcgt cacgcacgag atgggcttcg cccggtccgc cgccaaccgc gtggtgttca
    18241 tggccgacgg ctgtgtcgtc gaggaccggg tcccggagga cttcttcacg tccccgtcga
    18301 gcgaccgcgc caaggacttc ctgtccaaga tcctcaagca ctgagggggg attccatgtt
    18361 gcgtacgagg aacacgcgta cgggcagggc cgccgccctt gtggccggtc tcctgctcgc
    18421 cgcactcgcc gcgggctgcg gcaaggacgg cagccctccg gtcaagggcc ccaaggccga
    18481 ggccctgccg gtgtaccagg tcgacaccgg cttcgaactg cccgactccc gcacctggac
    18541 caaggcgaag cggcgcggct atctcatcgt cggcgccaag gaggaccagc cctacctggg
    18601 ggagaaggac ccggcgagcg gcatctactc cgggttcgac atcgagatcg cccgcatgat
    18661 ggcggcctcg ctcggcttcg aaccgaagac gatccgcttc cgcacgatcg cctccgccaa
    18721 ccgtgagacg gccctgcaga acggccagat cgactactac gtcggcacct acaccatcaa
    18781 cgacatgcgc aagaagctcg tcggcttcgc cggcccgtac tacatggccg gccagggact
    18841 gctggtgcgc accgacgagg acgacatcaa ggggccccag gacctggcgg gcaagaccgt
    18901 gtgctcggcg gccggctcca cgccctacca gcggatcgcc gccgactacc ccaaggcgac
    18961 cctcgtcgcc tacgacacgt actcgatctg cgtcgacaac ctcctcacct accaggtcga
    19021 cgccgtcacc accgacgacg cgatcctgct gggcttcgcc gccaaggcgc ccgaggagat
    19081 gaaggtcgtc ggcaagccct tctccgagga gccgtacggc atcggcgtac cgcgcagcga
    19141 caacgccctg cgcaacgccc tcaacgacgc cctggaggcc aacgagagag acggcaactg
    19201 gaagaaggcg tacgacgcga cgctcggcct ctccggggcg cccgcgccga ccccgccgcc
    19261 catcgaccgc tacccggcga cctgagggga cgcgcctcac ccatggacgt actgacagag
    19321 aacttctccc tctacggcaa gggcttcctc ggcaccgtcg aactgaccgt ctacgcctcg
    19381 gcgctggcgc tcgtcctcgg cttcctgatg gcgtccttcc gggtcgcgcc cgtcggctcc
    19441 ttccgggtgc tgggcacggt ctgggtcacc gtgctccgca acaccccgct gacgctgctg
    19501 ttcttcgcgg tcctgctcgg cctgccccgc ttcgggctcg tcctgccgtt ccagctcttc
    19561 gccgtcatcg cgctcggctg ctacacctcg gcgttcatct gcgaggtgct gcgctccggc
    19621 atcaacaccg tgcccaaggg ccagggcgag gcggcccgca gcctcggcat gaacttcggg
    19681 cagaccctga gcaccgtggt cctgccgcag gcgttccggt cggtgatccc gccggtcggc
    19741 tcgaccctga tcgcgctggc gaagaactcc gccatcgccg gggcgttcag cgtcaccgaa
    19801 ctcctcggca cctacaagac gctcaacgaa ctgggctaca gcatcatctg gtccttcatc
    19861 tggatcgccg tcggctacct gatcatcacc ctgaccatca gcgcggtgtt caacgtgatg
    19921 gagaagcgct ggggagtcgc acgatgacca agaccctcac ccgcaaggcg tcccgggctt
    19981 cggcgcccga ggcaaccgcg ctctacgaca tcccgggacc ggtgacccgc agacggcacc
    20041 tgatgtacgg gatcgcctcc acggtggtga tcctggcgct gttcggctgg atcgtctacc
    20101 tgctcttcga caccgaccag ttcaccgcgg agaagtggac gcccttcgag tacaagggca
    20161 ttcaggaact gctgctgcgc ggcctcggca acaccctcaa ggcgttcgcg tacgcggcgg
    20221 tcctctcgct ggcgctcggc gcggtcctcg ccgtcggcag gctctccgaa caccgggtgc
    20281 tgcgctggat ctccaccctg ctggtcgagt tcttccgggc catgcccgtg ctcgtgatga
    20341 tcttcttcat cttcgtggcg ctgaaggtcc agccgctgcc cgccctcgtc gccgggctga
    20401 ccctctacaa cggctcggtc ctcgcggagg tgttccgcac cgggatcaac gccgtggacc
    20461 ggggccagcg cgaggcggcg tacgcgctcg gcatgcgcaa gacccaggtc accacgtacg
    20521 tcctggcgcc ccaggccgta cgcgcgatgc tgccgaccat catcagccag ctggtggtcg
    20581 cgctgaagga cacctcactc ggctatctga tcacctacga ggaattcctc cacgccggaa
    20641 agctgatcgc gtcgaatctc gactacgatc ttcccttcat ccccgtcgtg atggtgatct
    20701 cgccgatcta catcgggatg tgcatgctgc tctcgtggtt cgccacctgg gtggccaagc
    20761 ggcagcggcg caacctgaaa accagagcgg tcggggtcgc cccggccgaa ccggggacgc
    20821 tgctgccggg agggcagtag ccgggcagtg cccgcccggc agcagccggt gatcacttct
    20881 cgcgcagcgg gaccgggaga tgacccgggt ccgtgccggg cgaggagaag gtcagctgat
    20941 gccggtcggg ttgtgctcga tgtacagcgg atcgacggtg tccggggggc cgaacgggcg
    21001 ctaccgggtc acttcagggc gctcttggcc tgccagtccg cccacgagac gttccacgcg
    21061 ccgtacccgt tgccctcggc gaccgtgccc ttggcctccg cgccggtcat ctcgaacggg
    21121 tcgcccaccc gcacctgccc gtacagcgcg gcggcgtcgc cgtcgctcat cccgaggcag
    21181 cccgaactcc ggttggcccg gccgaagaag cccgcgttcc acggtgccgc gtgggcgtac
    21241 atccccgacc aggtcagccg catcgagtag tcgaccatct tgtcgtaggc gtcgccgagg
    21301 cccaccgtct c
//
