LOCUS       NZ_KZ819178            26449 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. CS131 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ819178
VERSION     NZ_KZ819178.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS131
  ORGANISM  Streptomyces sp. CS131
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7968990)
  AUTHORS   Malmierca,M., Ceniceros,A., Mendez,C., Salas,J.A. and Olano,C.
  TITLE     Genome analysis of twelve Streptomyces spp. associated with Peruvian
            leafcutter ants
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7968990)
  AUTHORS   Malmierca,M., Ceniceros,A., Mendez,C., Salas,J.A. and Olano,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2018) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 88.88x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003116755.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 09:38:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,994
            CDSs (total)                      :: 6,912
            Genes (coding)                    :: 6,769
            CDSs (with protein)               :: 6,769
            Genes (RNA)                       :: 82
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 41 of 143
            Pseudo Genes (incomplete)         :: 122 of 143
            Pseudo Genes (internal stop)      :: 12 of 143
            Pseudo Genes (multiple problems)  :: 31 of 143
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:40:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6298879
            Orig. end                         :: 6325328
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ819178.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Professor JA Salas
            laboratory.
FEATURES             Location/Qualifiers
     region          1..26449
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="27"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26449
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26449
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16449](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16449
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(563..574)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            1119..2534
                     /locus_tag="DBP20_RS28405"
                     /old_locus_tag="DBP20_28425"
     CDS             1119..2534
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DBP20_RS28405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DBP20_28425"
                     /product="hypothetical protein"
                     /protein_id="WP_162600208.1"
                     /transl_table=11
                     /translation="MSSQLGVTARTAGDLVSALKPDPRRTVIVLPDLHAGVGDPAGFAE
                     LVVGLASLQQVRLVVEVRNTNPLFTAFRPTAPAVMDLDETQWNDLVQAEPKLDDHDPLQ
                     RYISPASGLDVPASVCSADPLRVTAGYEAAEADHGGLRTAWLRVGQALLQDQPPAERAL
                     LLRTALGDAADPRIAPQLADLAVGAEWELFWSRVSGDITPPWPGPVSALALGAGPIEGQ
                     VLLSDHLGVLRTVDLATVTPRGRLAEPVKGIIALGVLSDGAVLALNYEGLHVQTPYQTV
                     RTSGLTALLDDGPTPVEQAIEAVDTTLRGSTPTAMAATDERLAVGDADGSVHVIGLDTP
                     DSTVLTQRLHRGAVNSLAAVTLPLGGDKATTVLLYSGGADGSVRAWAPGHEPQEAPVTE
                     RPYPVASLSAAHTTDGPLLAIAWGDGLIGYHRLDSGEAAFLGPGLRANGVMVTADGDLV
                     VGTNEAVFRLTPR"
     misc_feature    1932..1934
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(2590..2605)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            2637..4262
                     /locus_tag="DBP20_RS28410"
                     /old_locus_tag="DBP20_28430"
     CDS             2637..4262
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963827.1"
                     /locus_tag="DBP20_RS28410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28430"
                     /product="nucleic acid/nucleotide deaminase
                     domain-containing protein"
                     /protein_id="WP_109180456.1"
                     /transl_table=11
                     /translation="MGKTLPGELVEVLDLVGVSWPNIDEDEVRGCAKDYRKLAEGLRDV
                     ITEGNNACSNIVGGRSKGLTVTAIDRRWGKLTSKDLTTFAKALDDLGDALDDCAALIEG
                     CKVVCIAELGATAAAATAGVVGMFFTVGLSGLLSAGAILACRIALHEAIDYAVGEITSI
                     VTDKIEAKILSKIEAVFTDHLDADDNPADYASGSADMAQDLVIEFDEFDRASGGYKETR
                     DNFDKKKGEHKSGGGSRRSSVKKDSRFHKLSTVMDKAEDAVDKKADETVDILEKHGGNI
                     DKSKKEHKQTDKERKEDLDRCKVDGGDDVPMYLLNADGTVEQLHADGRTPTKINGTEVG
                     IRDILESDGTVWRSRATDKGNNPFGLSPSPENPKVESKRLGKNQTSDLAYATQLARYSK
                     GDYKGGNYAAADYVDADGNKVVLVGHSKGVHSERTIGYPVLKHGKESGIQSIYTEREPC
                     QESGSWCDQWLGKHFGENLEVSHSLSYDQSSVDGKRPSSYSIDGEHRAYRKNLEDWHNK
                     NGLGAMMTESDGTQMEAARKGKRG"
     gene            4266..4853
                     /locus_tag="DBP20_RS28415"
                     /old_locus_tag="DBP20_28435"
     CDS             4266..4853
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309221.1"
                     /locus_tag="DBP20_RS28415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28435"
                     /product="SUKH-4 family immunity protein"
                     /protein_id="WP_109180457.1"
                     /transl_table=11
                     /translation="MLFDVDHGALAAAVGVGNVHRLPAGTAERYGFTADTFDFLTEVGI
                     PSAEDYEISFGLPAEFDDGYIWRRAEQESQGWKFPERVEALIKIGNFPINAVVIDPVTG
                     VVYQYTDASMEAIPVHADVSSLAKTIGSFVEYVGNYTRGDGEDDEDVEYARRKREVDAI
                     HDAIRLVDPLPFAHEYSEWVEMFDNLEGGIYT"
     gene            complement(4925..5812)
                     /locus_tag="DBP20_RS28420"
                     /old_locus_tag="DBP20_28440"
     CDS             complement(4925..5812)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008746450.1"
                     /locus_tag="DBP20_RS28420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28440"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_109180458.1"
                     /sec_met_domain="APH (E-value: 1.9e-22, bitscore: 79.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPSASEPARHVVKQACSAVGLDSDGAEPLRLAENQIWRLPRQRV
                     IVRIAREGQSAAAAREVRVARWLARENVPAVRLVDVEQPVEADGRPVTFWAELPPQQHG
                     SAEDVAELLARLHSLTTPAIELGYLDPFVRVGERLHAATTIRDDDKQWLNALHSDLLAA
                     WAERPAGLPDRAVHGDAWPGNIVRTAGGVLMMDLERFSVGPPEWDLVSTAVRAKTTGAV
                     SAREYDRFCAVYGYDVTAWEGYPILARARELRMVTYAAQHAADNTEWGNQAQFRIDCLR
                     GRSGPRPWSWKGIL"
     gene            complement(5809..7200)
                     /locus_tag="DBP20_RS28425"
                     /old_locus_tag="DBP20_28445"
     CDS             complement(5809..7200)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031332.1"
                     /locus_tag="DBP20_RS28425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28445"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_239475400.1"
                     /transl_table=11
                     /translation="MKQLDPGASPQEWFGNELRRLRLGQGLSAKELGRLVQVSDDMILS
                     IEKGKYPSCRRDVAQRLDDVLGAGGLLDRAWPMVFGNRDADKRQADADKASPCRGERPT
                     QVPTGRILGRDEPTIRPGSHEPVIRRSFLQIGGLAAIAPLNFTDVFAPAELSLPTHVNP
                     GHVDQVLAVATAISGMDNELGGGGVVRDVAARAMQWSAGLLQAQSPEHMRTDLFAAVSR
                     LGIVVGASAFDAYHHDEATKTFRFAADCAEEAGDWHLRAKTYSFLARQAVWIGAPDDGL
                     TYAEKGLVRSDRLTATEQAMLHTARARAFGKMGNVRDTMAAVGAADEAFARARPTEESP
                     WMAYYDEAQHNGDTAHALFDLAILAGQDPGRAARRFNTAVNGHADAYKRSRAISRTKLA
                     SLLMAKGDPRQAAALGHAALNEVGRLTSRRAADDLRQLGRFASKHRTVREASALRDRIA
                     ATVSA"
     misc_feature    complement(7096..7098)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7267..7283
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.25"
                     /tool="antismash"
     gene            7436..7849
                     /locus_tag="DBP20_RS28430"
                     /old_locus_tag="DBP20_28450"
     CDS             7436..7849
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="DBP20_RS28430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28450"
                     /product="ATP-binding protein"
                     /protein_id="WP_162600209.1"
                     /transl_table=11
                     /translation="MDGQLDMSFNVRAENLGTVRDIVAAHLRWWRVDDGTAFRMLTVVN
                     ELFTNVLQHTPADADGCRMAGLLVQKVSDGVTAVVRDHDRRPPVYSSPALLAEEGRGLM
                     LLGALADDTSVSMTPAGKDVWVFMAIPELTEHL"
     misc_feature    complement(7449..7463)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.85"
                     /tool="antismash"
     gene            7889..8341
                     /locus_tag="DBP20_RS28435"
                     /old_locus_tag="DBP20_28455"
     CDS             7889..8341
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008746447.1"
                     /locus_tag="DBP20_RS28435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28455"
                     /product="DUF6415 family natural product biosynthesis
                     protein"
                     /protein_id="WP_109180461.1"
                     /transl_table=11
                     /translation="MSLTVLVPENDVVLPPADEPRTPQWSPPLDAEGLWSVLERIKNWK
                     PLDVEEVFDDLDTAIGDQTPPAAVTDPLVDRLRNHLKQLSDIAVADEQYPPTAEMLRLV
                     VRGVPLREECVPADYQQAIGLARRLAFVTSDLVEELIEAHYIKEAE"
     gene            8670..8873
                     /locus_tag="DBP20_RS36225"
                     /old_locus_tag="DBP20_28465"
     CDS             8670..8873
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009063233.1"
                     /locus_tag="DBP20_RS36225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28465"
                     /product="DUF5999 family protein"
                     /protein_id="WP_109180463.1"
                     /transl_table=11
                     /translation="MCAHNPPCPTAMAPDREAARPVAHRPEQGWSLLCNGVLVFEDTGE
                     LLPDGRIVAPHRTLALTVGSAA"
     gene            8870..9523
                     /locus_tag="DBP20_RS28450"
                     /old_locus_tag="DBP20_28470"
     CDS             8870..9523
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143560.1"
                     /locus_tag="DBP20_RS28450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28470"
                     /product="hypothetical protein"
                     /protein_id="WP_239475401.1"
                     /transl_table=11
                     /translation="MTTTAADLVVPYITARDGKEADSLLNLNVRIGPDRRPRLGYKDEA
                     EPDRDLRGVLWARYSMSLGFAGQPTGNPRWRLVHPLRQRITMALLRCQVCTVPLKRSDG
                     ILFVETADDGDDHTRPVKTAQPPVCLEHARMAARRCPRLRSKGHVALLATRFPLYGVIG
                     TPYQYTADGIQPLAASDATLPYNHPQIGWFLASQLVRELRDYEVVSLDDLVPAA"
     gene            9711..9890
                     /locus_tag="DBP20_RS28455"
                     /old_locus_tag="DBP20_28475"
     CDS             9711..9890
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825826.1"
                     /locus_tag="DBP20_RS28455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28475"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_109180464.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 6.2e-11, bitscore:
                     40.7, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRIVTKSTTQVQESTAGGQSDGFDLNVSLLEVSDAAGLTVLTDD
                     GCGSSCGACVTFTD"
     gene            10001..13096
                     /locus_tag="DBP20_RS28460"
                     /old_locus_tag="DBP20_28480"
     CDS             10001..13096
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612044.1"
                     /locus_tag="DBP20_RS28460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28480"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_239475402.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.8e-198,
                     bitscore: 658.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.1e-18,
                     bitscore: 65.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.6e-21, bitscore:
                     75.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIPPAFKAGTTALVRAAARPSVTQLPLPDFDDRSFRSEELEEAT
                     TGRLAWIRSIWHDPGIAQALRHASPVLAAEVEALECADSPSTREVRRVGVSVVRYLLRA
                     LHRPTPFGLFAGVTTATFDAEPHARWGQNHAVVARAGAEWVGRLIEQLERSGELLPLLS
                     VVVNNTTFERDGSLVVPYQDDGPTGQRRAVEASVELSAPVRLILRAADAPIRIGELAEK
                     LMAEFPAVAPERVKRLLAGLVRRRVLITNLHAPTTETDALGHLVTQLDAVRAEDIRLLA
                     PVVRELRAVHAGLEQCGTTGGRDAVATRMRDLVPGLRRHPLALDLCLDATVVLPDLVAR
                     EAERAATILTRLCARPYGTEPWNEYHQRFYERFGVGTMVPLMEVVADSGVGYPDGYPGR
                     PASEGRRRLSPRDDVLLRLAQAAALDGRDEVVLTDETVAALDRGPQEPRITSHLEVGVR
                     LHAASLAEVRRGRFTVELTSVSRGSGVTIGRFLGVLPHAQRKRLHEELADLPTADDGTV
                     AAQLSFPALLPDTAHVTRTPRVLPLVISLQEHRAPDAAVLSPADLAVACDGRRMYLAAP
                     SRGVRVEAVGMNALNLAEHTPPLARLITEVSRAQNAQVTRFDWGAAAAMPFLPRLRYGR
                     IVLVAARWRLEAGDLPDRHRPGADWDAALSGWRERRRLPQHVYLVQDDRRLPLDLDEPG
                     HRSLLRQHLDRAGTALLTEAAPPGADGWTGGRAHEIAVPLKAVRPPAWPALPTPTTART
                     LSPAQIQTPATSPVLLVALYGAPRRQDALLTRHVPDLMRRLGSPHWWYVRFRDPQQHLR
                     LRIALPDPDDFADTTHTVSAWADELRTAGLLADLRYPTSYRETGRWGSGPAWDAAEAVF
                     RADSLATVAQLAQPVRPAQRPLVAAHFFAIASALLGGPDAGAHWLIDHIEPTAPNPVPR
                     SQFTDAVRLADPRGDWAALRSAPGGAAIVDAWAERTAALATYRPHLSGPHADGIVVDGV
                     LTSLLHVHFVRHVAVDFPEEEVCLYLARAAALAFTARAGRRP"
     misc_feature    10454..10456
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        10490..10765
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DBP20_RS28460_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="8.60E-21"
                     /identifier="RREFam001.1"
                     /label="DBP20_RS28460"
                     /locus_tag="DBP20_RS28460"
                     /protein_end="255"
                     /protein_start="163"
                     /score="65.4"
                     /tool="antismash"
                     /translation="VVVNNTTFERDGSLVVPYQDDGPTGQRRAVEASVELSAPVRLILR
                     AADAPIRIGELAEKLMAEFPAVAPERVKRLLAGLVRRRVLITNLHAP"
     misc_feature    11684..11686
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13093..14358
                     /locus_tag="DBP20_RS28465"
                     /old_locus_tag="DBP20_28485"
     CDS             13093..14358
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010352621.1"
                     /locus_tag="DBP20_RS28465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28485"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_109180465.1"
                     /sec_met_domain="LANC_like (E-value: 1.3e-41, bitscore:
                     141.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHTAAAVAAAIADRLAHPDQAPTAATDDTNRQHLAYGPTGIALL
                     HIERAAAGLAPWQRAHDWLAASTREPFTGGPDSHPFYGAPALAHAVACAADQLPDSYRR
                     GLDVLDRQVTADARRRLDAAHRRIEAGQLPALAEFDAIRGLSGYGAYLLRRDPAGPVTR
                     AVLDYCVRLTDPVTDSGERLPGWWVPTGPSGRPGDRFPGGHANHGMAHGVGAVLALLAL
                     AARRRTTVTGHHQAMRTILAWLEQWKAPTGRGTAWPYWISREELRSGRPAAAAPRRPSW
                     CYGTAGLARAQQLAALALCDSDLQVEAEAALLDALSDRVQLRVTTDSGLCHGFAGLIHI
                     AARAAADADRATAGQLRAIIPALLTMLVPPGTAPDDAAALLLKDAAGAGLLDGAAGTAL
                     GLLTADSTDPPRTAWDACLLTA"
     gene            14380..16449
                     /gene="fxlM"
                     /locus_tag="DBP20_RS28470"
                     /old_locus_tag="DBP20_28490"
     CDS             14380..16449
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543781.1"
                     /locus_tag="DBP20_RS28470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28490"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_109180466.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.7e-26, bitscore:
                     90.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 7.4e-45, bitscore: 151.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPDRWQQHNITFPDRDTGQRAVTERLAPALLAAEADGQLSGWWF
                     MNKQPWRLRYVADEPAPIVLALLDDWMADGTAQSHMTGIYEPETEAFGGVDAMTAAHAL
                     FHEDSRHLLTYPIKDGHLGRRETAILLMSSLMRASGLDWFEQGDVWAKVSALRPGTGTP
                     GSPRLTSAMRTLMTTEARSLCRERGPLDGHGDWVAAFERVGTTLAYLAAQGDLTRGLRA
                     VIAHHAIFHANRAGLPSADQHILFNIAREAIMGSSENTASATESGFAAHSVSTVNTDTL
                     TAPGANAEQLRNALVDQIKADGHARTPAVEAALRTVPRHLFVPDTSLADAYDNSPVNVK
                     YDPEGTSISCASQPAVVALMLDQLEAQPGERILELGAGTGYNAALIGHLVGPSGHVTTI
                     DVDDDLVEGARAHLAAAGATNVEALTRDGALGHAEGAPYDRIIATVGAHGIPHAWLDQL
                     AEGGRLVTPQRLTGSVSRSIIYVKRDGRWQSVGSEMNTFMPLRRGIADDDRRAVPLSTD
                     GAVRVQAPAGLALDADALASVLDQPRVEEWTGMTVRAGESPEWMELFVSCVLPSGLIRM
                     LFPQTAKGTVLTEDPYPSATAAVEKGALTYLARRPSEQKTPEGDKLWEFGVIGHGPGSD
                     ELAAKVADTVRTWDREYRGRDATFEILPLDAPADEQPGVFVLDTPLNRVRVTWQ"
     gene            16540..17670
                     /locus_tag="DBP20_RS28475"
                     /old_locus_tag="DBP20_28495"
     CDS             16540..17670
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019982953.1"
                     /locus_tag="DBP20_RS28475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28495"
                     /product="hypothetical protein"
                     /protein_id="WP_109180467.1"
                     /transl_table=11
                     /translation="MDLNGHIAQRFPLIYRFRPACLPLPRRVHGLVELAVAAAAKADQG
                     LASAVYNQAALIASDLGLPDLARKMCHQHAASYLHAAPLPGMTAIRALEPVVNLARLQI
                     RAGAADDGRHRLLHLFDAVTNSTSAQFAGVHVPADLTLTDTDRHEVRTWLWKVVLADGT
                     RTLSTAGRWTEALAHIEEHRGIGQRMLDGRQVAVLAALNHTPTDAAALITMTTPGERWE
                     NAVTGCLDVMCKEALRGPAVPLLDTLVEDYVEHQPDQGMTVFDTRLGLTILDLLEPHQE
                     DAAHRMIAELHRRAAAATDGYAARECLADHRFTSLAEPRQVEAAQRLVRACALGSGSLP
                     EPWLARMTEALRGSDEVIRASVGHSHPQQEGTGAQG"
     gene            17866..18375
                     /locus_tag="DBP20_RS28480"
                     /old_locus_tag="DBP20_28500"
     CDS             17866..18375
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327529.1"
                     /locus_tag="DBP20_RS28480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28500"
                     /product="topology modulation protein"
                     /protein_id="WP_109180468.1"
                     /transl_table=11
                     /translation="MRKVAIVGCGGSGKSHLARELGRILDAPVTHLDAAFYDDRWNALP
                     IDKFTDVQRELVAQPRWVIDGNYNSTLQVRLEACDTVVLMDVSTVAALYGIFSRQIRHG
                     AGHKGNGVHNRIHWGVIKYVATYRRRMRPRVMAKIEEFRSGTDVVLLANRRQAHRWLRK
                     VAAEQS"
     misc_feature    complement(18653..18667)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.29"
                     /tool="antismash"
     gene            19232..19735
                     /locus_tag="DBP20_RS28485"
                     /old_locus_tag="DBP20_28505"
     CDS             19232..19735
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010644539.1"
                     /locus_tag="DBP20_RS28485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28505"
                     /product="hypothetical protein"
                     /protein_id="WP_239475498.1"
                     /transl_table=11
                     /translation="MEQLCSALSRRRGRPLYLREAPLPKPGPTGMWVEYDAYDVILYQQ
                     ETTRLHQDHIKLHEIGHILVAEAEDAEQASAEATGRPPVLDPDEESAFFVEGWAAMLPV
                     FDPETIKRVARRCTYDDGEECSVELAATIILEWASVLDDSTPLSEDPSLRRVQSALGDR
                     RGWL"
     gene            19739..20887
                     /locus_tag="DBP20_RS28490"
                     /old_locus_tag="DBP20_28510"
     CDS             19739..20887
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046814.1"
                     /locus_tag="DBP20_RS28490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28510"
                     /product="MAB_1171c family putative transporter"
                     /protein_id="WP_109180470.1"
                     /transl_table=11
                     /translation="MELLLLGLVGALAWKLYKLWRAPHDAPLRSVTLCLLCATLSYPIA
                     MPGGTTGVDTVAGHGAAKLVQNVLLLFAMYFLMCFYLYSAADAEASRRRARTEAVVVGA
                     VVVVITLAAVSVPHEVFAGSFSTADMTIPQIAVFYGGAGCYLTYVLGLAARWTRTYARM
                     SRRPHATGLWMAAVGLGTMAVACATRAVIVAVRWFEIDVPQRLMAAVAFLLVASILLFT
                     AGITYTGVRARISSSKLWLQHRRDYRRLAALWELLAEAFPDSVLPPASSSAHDRRRARG
                     VHRRYHRRIVEIRDGLVAISPYLLEDETGIGSPDVDSVELAARLRRASVRIKVGALAPR
                     RAVPLAMALGSDRAADVKQLIAVSDALVTDRANPLTIKEAPC"
     gene            20881..22068
                     /locus_tag="DBP20_RS28495"
                     /old_locus_tag="DBP20_28515"
     CDS             20881..22068
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046813.1"
                     /locus_tag="DBP20_RS28495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28515"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_109180471.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 2.2e-41, bitscore:
                     140.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLISGRRVLVDTGTYLDDGAVLIEGDSIVAVGPRKEIEEQTAADV
                     PRSVFDGTLLPGLIDAHVHLIFDGGPDPVSALQDPTDEALLADMRRRAGELLLSGVTTA
                     RDLGDRNGLALRLDAEIAAHRTPGPRIVSAGTPLTTPGGHCHFLGGEVSGEAEIRALVR
                     LNLERGAGVIKCMVTGGGLTRGGPASHESQFSATELRLLVDEAHAAGVPVAAHAHGADG
                     IAAAVDAGVDTIEHCTWMTGDGLDFRRDVVQQIIDRDITVCPAVSPHWRMLPAIFGEER
                     AAAMFDLVRQMADAGVKLIAGTDAGVQRANFSGLVPALSFYAHLGLANAEIIDMATTAA
                     ATALGLGSTTGRIAPGYRADLIVVDGDPLSDLDALKNIKAVFASGGRHEPNAPAE"
     gene            complement(22126..23019)
                     /locus_tag="DBP20_RS28500"
                     /old_locus_tag="DBP20_28520"
     CDS             complement(22126..23019)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046812.1"
                     /locus_tag="DBP20_RS28500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28520"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_109180472.1"
                     /transl_table=11
                     /translation="MPARHFDRTVVRAVRRAAEIPQAEVGAAVDAADSTVAGWELGSSV
                     PDQEKLPGIARVLRKPLDELFPRKGTPDLIDLRCDAGLYRYEVARFIGTKSDGPVAAAE
                     NGVRRLKEKYVPKLAAAYGVSERVLEQAQERSFGNTVEEAGDESVAGAEAEESPRTLGE
                     KISFLLEQSYPAGAAPGDEEIAEAVNRHAGSEVVTANEVEALRTGTGEADSPPPVVLEG
                     LAEFFGVERMYFEPDDAVARQVYQGIRVLLASKNGGIRRVRARGLGPEGLSPEVLSLLT
                     DLETEFEKQVGSEDAE"
     gene            23412..23738
                     /locus_tag="DBP20_RS28505"
                     /old_locus_tag="DBP20_28525"
     CDS             23412..23738
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972991.1"
                     /locus_tag="DBP20_RS28505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28525"
                     /product="transcriptional regulator"
                     /protein_id="WP_109181636.1"
                     /transl_table=11
                     /translation="MPAMPSGTPACPDTSRRGRLAAQLADMISGAATIRVSLTDPTHVW
                     PHPHTVVQDETGKTMELGRTASRVAARWILRVWPDKDWTRPHTFRLADATLTRSDLTAA
                     ERGR"
     gene            23740..24753
                     /locus_tag="DBP20_RS28510"
                     /old_locus_tag="DBP20_28530"
     CDS             23740..24753
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972990.1"
                     /locus_tag="DBP20_RS28510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28530"
                     /product="hypothetical protein"
                     /protein_id="WP_109180473.1"
                     /transl_table=11
                     /translation="MARIRTIKPEAFTSESLAEVNVAAERTFFGLLTQADDHGRHRDNA
                     AIIAGLLWPLRAEHTSVHVEDDLHQLANAGLICRYTGCDGRRYLHIVTWSEHQKIDKPS
                     QSRLPSCPQHQAADRCAPCKGSCTREGPSTPPRGLAETSGRTSRALDLPAVPTSATPDH
                     AGGPTADQQEAADGTISAPGRGGAKSAGQRTFSEGSPNLPRSRSEGSAPGSRILDPGSL
                     VPTGRTAPAPSVSAKDLVGEYVAGCDRRPPNDVIGHLGRITKKLLDEGIAPDHIRAGLA
                     NYAANPKHPSVLTSMVNEAMNARPGGLARPGIRPNVPAHQAWTNPANASAAYAEEL"
     misc_feature    complement(23770..23781)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     gene            24753..25457
                     /locus_tag="DBP20_RS28515"
                     /old_locus_tag="DBP20_28535"
     CDS             24753..25457
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972989.1"
                     /locus_tag="DBP20_RS28515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28535"
                     /product="ATP-binding protein"
                     /protein_id="WP_030624100.1"
                     /transl_table=11
                     /translation="MHTRHREPQLLGNEATLERMARILAARNIDPADAALPDDAEPFSP
                     LDALLAGMPPRYQAAVADHPTVLEWVRKVTDAAVAPSRGARRQVTTGPSLLMAGVVGAG
                     KTHQAYGAVRALVQSGVGARWRATTAADLYADLRPRPGVDSERELAAVSRCPLLIIDDL
                     GAAKASEWVEEITYRLINRRYNYELPTLITTNLAIKDLRSYLGDRVASRLAQMTTRVEF
                     EAVDRRRHSAAA"
     gene            25574..26140
                     /locus_tag="DBP20_RS28520"
                     /old_locus_tag="DBP20_28540"
     CDS             25574..26140
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046808.1"
                     /locus_tag="DBP20_RS28520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_28540"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_109180474.1"
                     /transl_table=11
                     /translation="MTSTMNGPAQHRQLGDQTWQADAVCQSTEYNPVDPEVFFPEPDET
                     AKIATAKALCGQCPVRRTCLDAALEGGDTDGIRGGLTEEERGPLHDKLASRLDYSRVNA
                     TIAGRDVHLTHTERRAVEYAAYRHGVSEQRLAWLLKVTEEHAKKRYREIRRAERNRTLN
                     QPTTNTTPPETSGERLIRDDFGTAA"
     misc_feature    complement(26249..26263)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.13"
                     /tool="antismash"
ORIGIN
        1 gtcagtccca gtgccggatc catgtgttgc ccacttcgga tcgggcggcc tgaggaggtt
       61 ctcggcagct gaaatcagtg gtcgccgtct gcagggtgcc agcgcagcgg cgcttgcgga
      121 agtgggtgtg cccgttcatg tcacgccgta cttcagagct gcgaggccga cagattctgc
      181 tgccctggga gtcttcgccg cacacggcgg tgctgtcgcc ccgtcggcgg agaaggaagg
      241 ctggctgcgg ctcggttcag acggactcgc gcacctgtgt gtccggcccg atgaggcggt
      301 gcaggccgtg tttctggggg gcggtgagga ggacatgttc gtcaaccaga gtgtttccgc
      361 cttcaacgcg gccctgactg ccctggatcg gcagcttcca gtgattgctg cggccccgga
      421 cctcgcgact gcggcgacgg cgttccgcga gctgaactcg gaggtccgtc agcttgacga
      481 cgaggcgttc gcccagcgtg agagctggtg gccgcgcgtc ctggacgacg tgcgtcacac
      541 gctcaacttc ccgttctcgg ccgcgttcga gtacatcgac gctaacggtg ccaagcaggt
      601 ggccacggag gcgacaggtc ctggccgggc gcacccggag gagcttgtat gggcgcgtct
      661 ggagggcgag ggcatcacac cacagcaggt gcggcgggtg tactgcgagc tcgagccgtg
      721 catgttgccc ggccgctact gtgccgtgtg gatgcagcga accttccctc atgcagagtt
      781 cacgcatagc tatgatttcg gcagcgatgc agagtcccgt gaggcgggcc tgcgggaact
      841 gatcatccag accgcccagc agtccgctgc cggtgagtag ccgcgtgtgg ccgcggcccg
      901 gtggaggcag ggatctcgcc ggcgccgcgc tgctggggtg gctggcggat ccggccgctc
      961 cccaattgtg tctggtgacc ggcggcgctc agtgcggcaa gtcgaggctg ctggcctggc
     1021 tggtccggca cggttttcgc gccggaacgg tccccgaaag ggcggtgcac gcagtcgctc
     1081 cgatggacgg aacacgaata cgtgctgcgg tgtggtcctt gtcctcacag cttggtgtca
     1141 cagcgcgtac cgcaggcgac ctggtctcgg cgttgaagcc cgacccccgg cgcaccgtga
     1201 tcgtgcttcc tgatctgcac gcaggcgtag gcgatcccgc aggcttcgcc gaactggtcg
     1261 tcgggctggc cagcctccaa caggttcgcc tcgttgtcga agtccgcaat acgaaccctc
     1321 tcttcaccgc cttccgacca actgcaccag ccgtgatgga cctcgacgag acgcagtgga
     1381 acgacctcgt ccaggcggag ccgaaactcg acgaccacga tcccctccag aggtatatct
     1441 ctccggcatc cggcctcgac gtcccggcct cggtgtgctc ggcagacccg ctacgggtca
     1501 ccgccggcta cgaagccgcc gaggcggatc acggtggtct tcgcaccgca tggctgcgcg
     1561 tcgggcaggc actacttcag gaccagccgc cggccgaacg cgcgctgctc ctgcggacgg
     1621 cactcggtga cgcggcagac cccaggattg ccccgcaact agcggatctt gctgtaggcg
     1681 cggagtggga gctgttctgg agccgtgtga gtggcgacat cacgccaccg tggccggggc
     1741 ctgtctccgc actggcgctg ggcgccgggc cgatcgaagg ccaggtactg ctatccgacc
     1801 acctcggggt gctgcgcacc gttgaccttg cgacagtcac gccgagaggc cgcctggctg
     1861 aacccgtcaa agggatcatc gctctcggcg ttctctcgga cggagcggtt ctggccctga
     1921 actacgaggg cttacacgtg cagacgccgt atcagaccgt gcgaacttcc ggtctgaccg
     1981 ctctcctcga cgatggcccc acacccgttg agcaggcgat cgaggccgtc gatacgacct
     2041 tgagaggctc tactccgacc gcgatggcag caaccgacga acgcctggcc gtgggcgacg
     2101 ccgacgggtc ggtacacgtc atcgggctcg atacgcccga cagcaccgtc ctgacgcagc
     2161 ggctacaccg cggcgcggtc aactcccttg ccgcggtgac tctgccgctc ggtggagaca
     2221 aggcgaccac ggtgctgttg tacagcggtg gggcagatgg cagtgtccga gcctgggcgc
     2281 ctggacatga gccgcaggaa gctccggtca ctgagcggcc ctacccggtc gcctctctca
     2341 gcgctgcaca cacaacggac ggtccgctgc tcgcgatcgc ctggggggac ggcctgatcg
     2401 gttaccaccg gctggacagc ggagaagcag ccttccttgg cccgggcctc cgggccaacg
     2461 gggtgatggt gactgctgac ggtgatctcg tggtgggaac caacgaagcg gtcttccgcc
     2521 tcactccacg atgacctcgc ctattccgct gccaggcatg gccgacttcc cggttgacgg
     2581 gttgtcaggg tgacggcaca gtgacgcaag ttgactgatg agggggacaa cgacctgtgg
     2641 ggaagacgct gcctggtgag ctcgtcgagg tattggacct cgtcggtgtc tcctggccca
     2701 acatcgatga agacgaggtg cgcggctgcg ccaaggacta ccgcaagctc gcggaaggac
     2761 tgcgcgacgt catcacggag ggcaacaacg cctgttcgaa catcgtcggc ggccgcagca
     2821 agggcttgac ggtcacagcc atcgaccgcc gctggggcaa actcaccagc aaggatctga
     2881 ccacctttgc caaggcgctg gacgacctcg gcgacgccct ggatgactgt gccgccctca
     2941 tcgagggctg caaagtcgtc tgcatcgcgg agctcggagc aaccgcggcc gcagccacag
     3001 ccggcgtcgt cggcatgttc ttcaccgtgg gtctcagcgg tctgctcagc gcaggcgcca
     3061 tcctcgcctg ccgtatcgct ttgcacgaag ccatcgacta cgcggtcggt gagatcacct
     3121 ccattgtgac cgacaagatc gaagcgaaga tcctatccaa gatcgaagcg gtattcaccg
     3181 atcacctgga cgccgacgat aatcctgcgg actacgcgtc gggcagtgca gacatggcgc
     3241 aggacctcgt catcgagttc gacgagttcg accgggcatc gggaggatac aaggaaaccc
     3301 gcgacaactt tgacaagaag aagggagaac acaagagcgg cggtggaagc cgtcgcagct
     3361 ccgtcaagaa ggatagtcga ttccataagt tgtcaaccgt catggataaa gccgaggacg
     3421 cggtcgacaa aaaagccgat gaaaccgttg acatccttga aaagcacggt ggcaacatag
     3481 acaagagtaa aaaggagcac aagcagaccg acaaagagcg gaaagaggac ctggaccgct
     3541 gcaaagtcga tggcggcgac gacgtcccga tgtatttgct caatgcggac ggcacggttg
     3601 agcagctaca tgcagacgga cgtacaccca cgaagataaa tggtaccgaa gtcggcatcc
     3661 gcgacatcct cgaaagcgac gggacggtat ggcgatcccg ggcaaccgac aaggggaata
     3721 accccttcgg tctgtcgccc tcacccgaaa acccgaaagt cgaatcaaaa cggcttggga
     3781 agaatcaaac gagcgatctg gcctacgcca cacagttggc cagatactcc aagggcgact
     3841 acaagggggg caactacgca gccgccgact atgtcgacgc ggacggaaac aaggtagtgc
     3901 tggtcggaca cagtaaggga gtccattccg agcgcacgat cggttatccg gtgctcaaac
     3961 acgggaaaga atcaggaatc caatcgattt acacagagag agagccgtgt caggagtccg
     4021 gatcctggtg cgaccaatgg ctcggcaaac actttgggga gaatttggaa gtcagccact
     4081 ccctaagcta tgatcaatct tccgtggacg ggaagcgccc ttcttcctat agcatagacg
     4141 gtgagcaccg cgcctaccga aaaaacttgg aagactggca caataaaaat ggtctcggtg
     4201 cgatgatgac cgagtcggat gggacgcaaa tggaagccgc gaggaaaggg aagcggggct
     4261 agagcatgct gtttgatgtc gaccacggcg cactggcggc tgccgtcggc gtgggtaacg
     4321 ttcatcgcct gccagccggt accgcagagc gttacggatt cactgcggat acattcgatt
     4381 ttctcactga ggttggaatt ccgtctgccg aggattacga aatctccttc ggtctcccag
     4441 cggagttcga tgatggttat atctggcgcc gcgcagaaca ggaatcgcag ggctggaagt
     4501 tccccgagag ggtcgaggcg ctgatcaaga tcgggaattt ccccatcaat gccgtagtca
     4561 tcgaccccgt cacgggagtc gtctaccagt acaccgatgc ctcaatggaa gcgattcccg
     4621 ttcatgctga tgtttcctcc ttggccaaga ccatcggatc tttcgtcgag tacgtcggaa
     4681 actacactcg cggtgatggc gaggatgatg aggacgtgga atatgctcgc cgcaagcggg
     4741 aagtcgacgc cattcacgac gcgatccgcc tcgtagaccc gctgccgttc gctcatgagt
     4801 acagcgaatg ggttgaaatg ttcgacaacc tcgaaggcgg gatctacacc tgacggcctt
     4861 cgtttttcct tgcggttggc gggaatccag aagttgtttc ccgcgaactc ttaaacgccg
     4921 cgtctcagag gatccccttc cacgaccacg gtcgcgggcc ggatcgacca cggagacagt
     4981 cgattcgaaa ctgcgcctga ttcccccact cagtgttgtc ggctgcgtgc tgagccgcgt
     5041 aagtcaccat gcgcagctca cgggcgcgcg cgaggatggg atagccctcc cacgccgtca
     5101 cgtcgtaccc gtacaccgca cagaagcggt cgtactcgcg tgcgctgacg gcgcccgtgg
     5161 tcttcgctcg cacggcggtg gacacgagat cccactccgg gggcccgacg gaaaagcgtt
     5221 ccaggtccat catcaggacg ccaccggccg tgcggacgat gttgccgggc caggcgtcac
     5281 cgtgcacggc ccgatcgggg agaccggccg gccgctccgc ccaggccgct aggaggtcgc
     5341 tgtgaagggc gttcagccac tgcttgtcgt cgtcgcggat cgtggtggcc gcgtgcagcc
     5401 gttcgcctac ccggacgaag ggatcgagat accccagctc gatcgccggc gtggtcaggg
     5461 agtggagcct cgcgaggagt tcagcgacat cctcggccga gccgtgctgc tgcggcggca
     5521 gttccgccca gaaggtcacc ggcctgccgt ccgcctctac cggctgctcc acgtcgacca
     5581 agcgaacggc cggcacgttc tcccgggcga gccaacgtgc gacgcgcacc tcgcgggccg
     5641 ccgcagcgct ctgtccctcc cgggctatcc gtacgatcac ccgctgacga ggcagtcgcc
     5701 atatctggtt ctcggccagg cggagaggct cggctccgtc ggagtccaat ccgaccgccg
     5761 aacaagcctg cttcacgacg tgacgtgcag gttcggatgc cgaaggagtc atgcggaaac
     5821 cgtagcggcg attcgatctc gcagcgctga agcctctcgg acagtccgat gcttcgaggc
     5881 gaagcgaccg agctgccgca gatcgtcggc agcgcgccgg gaggtgagtc ggcctacctc
     5941 attcaaggcg gcgtgcccga gcgccgccgc ctggcgaggg tcacccttgg ccatgagcag
     6001 ggaggccagc ttcgtccgtg agatcgcacg agaccgtttg taggcgtctg cgtgtccgtt
     6061 caccgccgtg ttgaatcggc gcgctgcccg gcccgggtct tgtccggcga gaatcgccag
     6121 atcgaagagg gcgtgagccg tgtccccgtt gtgctgcgcc tcgtcgtagt aggccatcca
     6181 cggcgattct tcggtgggcc gggcccgagc gaacgcctcg tctgcggcgc cgacggccgc
     6241 catcgtgtcc cgtacgttgc ccatcttccc gaaggccctg gcccttgccg tgtgaagcat
     6301 cgcctgctcg gtcgccgtca ggcggtcgga gcgcacaagc cccttctcgg cgtacgtgag
     6361 gccgtcatcg ggtgccccga tccatacggc ttgtcgtgcg aggaacgagt aggtcttggc
     6421 ccgcagatgc cagtccccgg cctcctcggc gcagtccgcc gcgaaccgga aggtcttggt
     6481 ggcttcatcg tggtggtagg cgtcgaaggc ggaggcgccg accacgatgc cgagtcgcga
     6541 tacggcggcg aacaggtcgg ttcgcatgtg ttcgggggac tgggcttgca gcaggccggc
     6601 tgaccactgc atcgctcggg cggctacgtc tcgcaccacg cccccgccgc ccagctcgtt
     6661 gtccatgccg ctgatggcgg tggccacggc caggacctgg tcgacgtggc ccgggttcac
     6721 atgcgtcggg agggacagct cggcgggggc gaagacgtcg gtgaagttga gaggggctat
     6781 ggcggcgagg ccgccgatct ggaggaacga gcgtcgaatc acgggctcat ggctcccagg
     6841 gcgaatagtc ggttcgtctc tgcccaggat gcggcctgtc ggcacctgtg taggtcgctc
     6901 gccccggcac ggggaagcct tatcggcatc agcctgcctt ttgtcggcat cacggttgcc
     6961 gaagaccatc ggccacgccc ggtcgaggag tcctcccgcg ccgaggacgt catcaagccg
     7021 ctgcgccaca tcgcggcgac agctcgggta cttacccttc tcaatagaca ggatcatgtc
     7081 gtcgctgacc tgcactaacc gcccaagttc cttggccgac agtccctgcc cgaggcgcag
     7141 tcggcgcagc tcgttcccga accactcctg gggcgacgcc ccaggatcga gctgcttcat
     7201 tggctgcggc atgttctgcc cccgaagtcg ttgatgccga actcttcacc tctcggcatc
     7261 aggctctgca cgttctcggt gcgctctgcc taaatggttg ctgatcggtt ccagtccagt
     7321 acacaccgca acccacccct gctgaagggg ttccggcaga acggaggaag cagcgatgga
     7381 actactcgtc gacccccgag agcgggatgc ttctgttcga gccacgtcca ggagcgtgga
     7441 cggtcagctc gacatgagtt tcaacgtccg ggccgaaaac ctgggaaccg tgcgggacat
     7501 cgtcgcagcg caccttcgct ggtggcgcgt cgacgacggc accgcgttcc gcatgctgac
     7561 cgtggtcaac gaactgttca ccaacgtctt gcagcacact cccgcggatg ctgacgggtg
     7621 ccggatggct ggcctgctcg tccagaaggt gtcggacggc gtcaccgccg tcgttcgcga
     7681 ccacgaccgc cgtccgccgg tgtactcgtc gccggccctc ctggccgagg aggggcgtgg
     7741 gctgatgctg ctgggtgctc tggccgacga cacgtccgtg tccatgaccc cagcgggcaa
     7801 ggacgtatgg gtcttcatgg cgatccctga actgactgag cacttgtagc cccctgcggc
     7861 cggtacttgg cccttcccag gagtcccgat gtccctcacc gttctggttc cggagaatga
     7921 cgtggttctt ccgccggccg acgagccccg cacaccgcag tggagccctc cactcgacgc
     7981 agaggggttg tggtccgtcc tggaacggat caagaactgg aagccgctgg acgtggagga
     8041 ggtcttcgat gacctcgaca cggcgatcgg cgaccagacg ccgcccgccg cggtgaccga
     8101 ccccctggtc gaccgccttc ggaaccatct gaagcagctc agcgacatcg ctgtcgcgga
     8161 cgagcagtac ccgcccaccg cggagatgct ccgactcgtt gtacgcgggg ttcccctgcg
     8221 ggaggagtgc gtgccggccg actaccagca ggccatcggc ctcgctcgtc gcctggcctt
     8281 cgtcacctct gacctggtcg aagaactcat cgaagcccac tacatcaagg aggcggagtg
     8341 acgcaccacc ttgactccgc tcggcgctcg gccgtgaccg ccgaggcggt ggtcctcccg
     8401 caagacgcgt acgactctga gtactacgag aagcggatct ccgacaactg gctcctggac
     8461 aagagcgtcg ccatgcgcgc cacgcgcgtg tcgttccccg tagttcccga cgggggcacg
     8521 gggcgcgtcg ggggctaccc ggcgtcgtgt gtgtgcttcg gggggcggtg ccacaagtcc
     8581 cctttttcgg ccgtgcccga accgtgtttc cccaccgcac cgtagctgcg cgaagagggt
     8641 ccgacttccc acccgagagg acgagcacca tgtgtgcgca caacccgccg tgccccacgg
     8701 ccatggctcc cgacagggag gccgcgcgac ctgtcgcgca ccgccctgag cagggctgga
     8761 gccttctgtg caacggagtg cttgtcttcg aggacaccgg agaactcctc cccgacggcc
     8821 gcatcgtcgc ccctcaccgg acgctcgcgc tcacggtcgg aagcgcggca tgacgaccac
     8881 cgcggccgac ctggtcgttc cgtacatcac cgcccgcgat ggcaaagagg cggactccct
     8941 cctcaacctg aacgtacgca tcggtcctga ccggcgcccg cggcttgggt acaaggacga
     9001 ggcagagccc gaccgagatc tccgcggcgt gctgtgggcc cggtactcca tgtcactcgg
     9061 cttcgcggga cagcccaccg ggaacccgag gtggcggctc gtgcacccgc tccgccagcg
     9121 catcacgatg gcgctcctgc gctgccaggt gtgcacggtc ccgctgaagc gcagcgacgg
     9181 catcctcttc gtggagacgg ccgacgacgg cgacgaccac acccggccgg tgaagaccgc
     9241 gcagccgccg gtgtgtctgg agcacgcccg gatggcggcc cggcggtgcc cccggctcag
     9301 gagcaagggc cacgtcgccc tgctggccac gcggttcccg ctctacggcg tcatcggcac
     9361 cccgtaccag tacaccgccg acggcatcca gcccctcgcc gcctcggacg ctaccttgcc
     9421 ctacaaccat ccccagatcg ggtggttcct cgcctctcag ctcgtacgcg aactgcggga
     9481 ctacgaggtc gtcagcctgg acgatcttgt gcccgccgca tagacggctg ctcgacggtc
     9541 ctgggcaaag gaccggaccg tcgagcagca ccccagagct tcccggcccg accatcggac
     9601 cgggatggcc agaacctgaa cccatggcgc agccccgtcg ctacgccacg gtcctcaggc
     9661 tctggcaagc accacctgtc ctacacacca acgaatcacc tggagttgtt atgacgcgaa
     9721 tcgtcaccaa gagcaccacc caggtccagg agtcgacggc cggcggccag tcggacgggt
     9781 tcgacctgaa cgtctccctc ctggaggtgt ccgacgcggc cgggctgacc gtcctgaccg
     9841 acgacgggtg cggcagctcc tgcggtgcct gcgtcacctt caccgactga ccctgaccgt
     9901 ctgaacccgg tcatcaggtc atgaaccgcg gtcggtgccg tcgcgctact cggcgcgtcg
     9961 gctccgaccg cccctccaga cgcacgaagg gacacgtcac gtggctatac ccccagcgtt
    10021 caaggcgggc acgaccgccc tggtgcgcgc agccgctcga ccgtcggtga cccagcttcc
    10081 cctaccggac ttcgacgacc ggtccttccg atccgaggag ctggaggagg ccaccaccgg
    10141 acgcctcgcc tggattcgca gcatctggca cgacccgggc atcgcacagg ccctccgcca
    10201 tgccagcccg gttctcgccg ccgaagtcga ggccctggag tgtgctgact ccccttctac
    10261 ccgcgaagtc cgccgcgtcg gagtgtcggt ggtgcgctac ctcctgcgcg cactgcaccg
    10321 gcccacaccg ttcggactgt tcgccggagt caccacggcc accttcgacg ccgagcccca
    10381 cgcccgctgg ggccagaacc acgcggtcgt ggcccgcgcc ggtgcggagt gggtggggag
    10441 gctgatcgag cagttagaaa ggagcggaga gctgctgccg ctcctgtcgg tcgtcgtcaa
    10501 caacaccacc ttcgagcgcg acggcagtct cgtcgtcccc taccaggacg acgggccgac
    10561 cggtcagcgg cgagcggtcg aggcgtccgt cgagctgtcg gcgccggtcc ggcttatcct
    10621 ccgcgcggct gacgcgccga tccggatcgg ggaactcgcc gagaagctga tggccgagtt
    10681 cccggccgtg gccccggagc gcgtcaagcg gctcctcgcg ggcctggtgc gccgacgcgt
    10741 gctgatcacc aacctccacg cgccgacgac cgagaccgac gcgctcggtc acctcgtcac
    10801 ccagctcgac gcggtccgtg ccgaggacat tcgtctcctg gcgcccgtcg tccgggagct
    10861 gcgcgcggtc cacgccgggc tggagcagtg cggcaccaca gggggccggg atgccgtagc
    10921 gacccggatg cgcgatctgg tgccgggcct ccgccgtcac ccgctcgccc tggacctgtg
    10981 cctggacgcc accgtggtgc tccccgacct ggtcgcccgc gaggccgagc gcgccgccac
    11041 gatcctcacc cgtctctgcg cccgcccgta cggtaccgag ccgtggaacg agtaccacca
    11101 gcggttctac gagcggttcg gcgtcggcac catggtgccg ctcatggaag ttgtcgcaga
    11161 cagcggcgtc ggctacccgg acggataccc gggcaggccg gccagcgaag gccggcggcg
    11221 cctgtcgccg cgggacgacg tgctgctccg cctcgcccaa gccgccgcgc tcgacggccg
    11281 cgacgaagtc gtgctgaccg acgagaccgt ggccgccctg gaccgaggcc cgcaggagcc
    11341 gcggataacg tcccacctgg aggtgggcgt gcggctgcac gcggccagcc tcgccgaagt
    11401 ccgccgtggg cggttcaccg tggagttgac cagcgtgtca cgcggatccg gggttaccat
    11461 cggacgcttc ctcggcgtcc tccctcacgc acaacgcaag cgcctacacg aggagttggc
    11521 tgacctaccc acggccgacg acggcacggt ggcggcgcag ctttccttcc ccgcgctgct
    11581 gcccgacacc gcacatgtca cccgaacccc gcgcgtgctg ccgttggtga tcagcctgca
    11641 agagcaccga gcccccgacg ccgcagtcct ctcgccggcg gacttagcgg tggcgtgcga
    11701 cgggcgccgg atgtacctgg cggctccgag ccgcggcgtg cgtgtcgagg ccgtcggcat
    11761 gaacgcgctg aatctcgccg agcacacccc gcccctggcg cggttgatca ccgaggtgtc
    11821 ccgggcgcag aacgctcagg ttacccggtt cgactggggc gcagccgcag cgatgccttt
    11881 cctcccccgc ctgcggtacg gccgcatcgt gctggtcgcg gcccgctggc ggctggaggc
    11941 tggcgacctc cccgaccgtc accgccccgg cgcggactgg gacgcggcgc tgtccggctg
    12001 gcgggagcgc cgccgcctgc cgcagcacgt gtacctcgtc caggacgacc ggcgcctgcc
    12061 gctcgacctt gatgagcccg gccaccggag cctgctgcgc cagcacctcg accgcgccgg
    12121 tacggcgctg ctgacggaag ccgctcctcc cggggcggac ggctggaccg ggggccgggc
    12181 ccacgagatc gcggtacccc tcaaagcggt ccgtcctccg gcctggcctg cgctgcccac
    12241 gccgaccacc gcccgcacgc tctccccagc ccagatccag accccggcca cgtccccggt
    12301 gctcctagta gccctgtacg gcgccccgcg gcgtcaagac gccctgctga ctcggcacgt
    12361 gcccgacctg atgcggcgcc tcggctctcc tcactggtgg tacgtccgat tccgcgaccc
    12421 ccagcagcac cttcgcctgc ggatcgcact gccggacccg gacgacttcg ccgacaccac
    12481 ccacacggtc agcgcctggg ccgacgaact gcggaccgcc gggctgctgg cagacctgcg
    12541 ctaccccacc tcctaccgcg agacgggccg gtggggctcc ggaccggcat gggacgcggc
    12601 cgaggccgtg ttccgcgcgg actccctggc cacggtggcg cagctcgccc agcctgtccg
    12661 gcccgcccag cgcccgctcg tggccgcgca cttcttcgcc atcgcctccg cccttctcgg
    12721 cggcccggac gccggcgcgc actggctgat cgaccacatc gagccgaccg cacccaatcc
    12781 ggtaccccgc tcgcagttca ctgacgccgt gcggctggca gacccgcgcg gtgactgggc
    12841 ggccctgcgg tcagcgcccg gcggcgccgc gatcgtggac gcctgggccg agcgcaccgc
    12901 tgcgctcgcc acgtacaggc cgcacctgtc cggcccacac gccgatggca tcgtcgtgga
    12961 cggggtgctg acctccctgc tgcacgtcca cttcgtgcgg catgtcgcgg tggacttccc
    13021 cgaggaagag gtctgcctgt acctggcccg cgccgccgcc ctggccttca ccgcccgcgc
    13081 tgggaggcga ccgtgaccca caccgcagcc gcggtggccg ccgccatcgc cgaccggctc
    13141 gcccaccccg accaggcgcc gacggcggcc actgacgaca ccaaccggca gcacctcgcc
    13201 tacggcccga caggcatcgc cctgttgcac atcgaacgcg ccgcggccgg gcttgccccc
    13261 tggcagcgcg cccacgactg gctggccgcc tcgacccgcg agcccttcac cggcggcccg
    13321 gacagccacc ccttctacgg cgccccggcg ctcgcccatg ccgtggcgtg cgccgccgac
    13381 cagcttccgg actcctaccg gcgcggcctc gatgtgctgg accggcaggt gacggcagac
    13441 gcccggcggc gccttgacgc cgcgcaccgc cggatcgaag ccgggcagct tccggcactc
    13501 gccgagttcg acgccatccg gggcttgagc gggtacggcg cctacctgct gcgccgcgac
    13561 cctgcgggcc cggtgacccg ggccgttctc gactactgcg tgcgcctgac cgacccggtc
    13621 accgacagcg gcgaacgcct gccgggctgg tgggtaccga ccgggccgtc cggcaggccg
    13681 ggcgaccgct tccctggtgg gcacgccaac cacggcatgg cacacggcgt cggcgcggtc
    13741 ctcgcgctgc tggcgcttgc cgcccgccgc cgcaccaccg tcaccgggca ccatcaggcg
    13801 atgcgcacca tcctggcctg gctggagcag tggaaggcgc ccaccgggcg cggcacggct
    13861 tggccgtact ggatcagccg cgaggaactg cgcagcggcc ggcccgcggc cgcggcacca
    13921 cggcggccga gctggtgcta cggcaccgcg ggcttggccc gtgcccagca gctcgccgcg
    13981 ctcgccctct gcgacagcga cctccaggtc gaggccgagg ccgccctgct ggacgcgctg
    14041 agcgaccgcg tgcagcttcg cgtcaccacg gacagcggcc tgtgccacgg cttcgccggt
    14101 ctgatccaca tcgcggcgcg tgccgccgcc gacgccgacc gggccaccgc cggccagctc
    14161 cgcgccatca tccccgccct tctcaccatg ctggtcccgc ccggcaccgc cccggacgac
    14221 gccgctgccc tgttgctgaa ggacgcggcg ggcgccggtc tcctcgacgg cgccgccgga
    14281 accgcgctgg gactgctcac cgcggacagc acggacccgc cccgcactgc ctgggacgcc
    14341 tgcctactca ccgcctgaat ccgaccgaag gacttctcga tgcgccccga ccgctggcag
    14401 cagcacaaca tcaccttccc cgaccgggac acgggacagc gcgccgtcac cgaacgcctc
    14461 gccccggcgc tgctcgccgc cgaggccgac gggcagctca gcggctggtg gttcatgaac
    14521 aagcagccct ggcgcctgcg gtacgtcgcc gacgagcccg ccccgatcgt gctggccctg
    14581 ctggacgatt ggatggccga cggcaccgcg cagtcccaca tgaccggcat ctacgagccg
    14641 gagaccgagg cgttcggcgg tgtggacgcc atgacggccg cgcacgccct cttccacgag
    14701 gacagccgcc acctgctcac ctatcccatc aaggacgggc acctggggcg gcgcgagacc
    14761 gccatcctgc tgatgagcag cctgatgcgc gcctcgggtc tcgactggtt cgagcagggc
    14821 gacgtgtggg cgaaggtctc cgcactgcgc cccggtaccg gcactcccgg gtccccgcgc
    14881 cttacctcgg caatgcggac cctgatgacc accgaagccc gcagcctgtg ccgcgagcgc
    14941 gggccgctgg acggccacgg cgactgggtc gccgccttcg agcgtgtcgg caccacgctc
    15001 gcctaccttg ccgcccaagg cgacctgacc cgcggactgc gcgccgtcat cgcgcaccac
    15061 gccatcttcc acgccaaccg tgccggtctg ccgtccgccg accagcacat cctgttcaac
    15121 atcgcacgag aggcaatcat gggttcgagt gaaaacaccg cgtcagcaac agaatcaggc
    15181 tttgcggccc atagcgtcag cacggtgaac accgacacac tcaccgcccc cggggccaac
    15241 gccgaacagc tccgcaatgc cctggtcgac cagatcaagg ccgacggcca cgcccgcacc
    15301 cccgcggtcg aagccgccct gcgcaccgtg ccccggcacc tgttcgtccc tgacacctcg
    15361 ctggccgacg cctacgacaa cagcccggtc aacgtgaagt acgaccccga gggcacctcg
    15421 atctcctgcg cctcccagcc agccgtcgtc gccctcatgc tggaccagct cgaagcccag
    15481 ccgggcgagc gcatcctcga actcggcgcc ggcaccggct acaacgccgc cttgatcggc
    15541 cacctcgtcg gcccgagcgg acacgtcacc accatcgacg tcgatgacga cctggtcgaa
    15601 ggcgcccgag cccacctcgc agccgccgga gccaccaacg tcgaggccct gacgcgcgac
    15661 ggcgccctcg gccacgccga aggcgccccg tacgaccgga tcatcgccac cgtcggcgcg
    15721 cacggcatcc cccacgcctg gctcgaccag ctcgccgaag gcggccgact cgtcaccccg
    15781 cagcgactca cgggcagcgt ctcgcgctcc atcatctacg tgaagcgcga cggccggtgg
    15841 cagtcggtcg gctcggagat gaacaccttc atgccgctgc gccggggcat cgccgacgac
    15901 gaccgccgcg ccgtgccgct cagcacggac ggcgccgtgc gcgtccaggc cccggccgga
    15961 ctggcgctcg acgccgacgc ccttgccagt gtccttgacc agccgcgcgt cgaggagtgg
    16021 accgggatga cggtccgcgc cggggagtcc ccggaatgga tggagctgtt cgtctcctgc
    16081 gtcctgccat ccgggctgat ccggatgctc ttcccccaga ccgccaaggg cacggtgctc
    16141 accgaggacc cctacccctc ggccacggcc gccgtcgaga agggcgccct tacctacctc
    16201 gcccgtcggc cctcggagca gaagaccccc gagggcgaca agctctggga gttcggcgtc
    16261 atcggccacg gccccgggag cgacgagctg gccgccaagg tcgccgacac cgtccgtacc
    16321 tgggaccgcg agtaccgcgg ccgggacgcc accttcgaga tcctgccgct cgacgcgccc
    16381 gcggacgagc agcccggtgt cttcgtcctc gacaccccgc tgaaccgcgt ccgcgtcacc
    16441 tggcagtagc tgatccgcct gcgtagtgcc cgccgaccgg ccggcgggca ccacgcggcc
    16501 cttccccgct cctcgtcgtc ttcacccccg ggggacctca tggacctgaa cggacacata
    16561 gcgcagcgct tcccgctcat ctaccgattc cgacccgcct gtctgcccct gccccggcgc
    16621 gtgcacggtc tggtcgaact cgccgtcgcc gcagccgcaa aggcggacca gggactcgcc
    16681 tcggccgtct acaaccaggc cgccctcatc gcctccgacc tcgggctccc cgacctcgca
    16741 cggaagatgt gccaccagca cgccgcctcc tacctccacg ccgctccctt gcccggcatg
    16801 accgcgatcc gcgccctcga acccgtggtg aacctcgccc gcctccagat ccgcgcgggc
    16861 gccgccgacg acgggcgcca ccgcctgctg cacctcttcg acgctgtcac gaacagcacc
    16921 agcgctcagt tcgcaggggt ccacgttccg gccgacctca ccctcaccga caccgaccgc
    16981 cacgaggtgc gcacctggct gtggaaggtc gtcctggccg acggcacccg caccttgagt
    17041 acggccggcc gctggacgga agctctggcc cacatcgagg aacaccgggg catcgggcag
    17101 cgaatgctgg acggccgcca agtcgccgtc ctggccgccc tcaaccacac ccccaccgac
    17161 gccgccgcgc tgatcaccat gaccacaccc ggagaacgct gggagaacgc cgtcaccggc
    17221 tgcctcgacg tgatgtgcaa agaggccctt cgcggcccgg ccgtacccct cctcgacacg
    17281 ctggtcgagg actacgtcga gcaccaaccc gaccagggca tgaccgtctt cgacacgcgc
    17341 ctcggcctga cgatcctgga cctgctggag ccgcaccagg aagatgcagc gcaccggatg
    17401 attgcggagc tccaccgccg ggccgccgcg gcgaccgacg gctacgccgc ccgtgaatgt
    17461 ctggctgacc accggttcac cagtctcgcc gagccgcgcc aggtcgaggc ggcccaacgg
    17521 cttgtccgcg catgcgcgct ggggagcggc agcctccccg agccctggct cgcaaggatg
    17581 acagaggcgc tgcggggcag cgacgaggtg atccgcgcca gcgtcggaca ctcccaccct
    17641 cagcaggaag ggactggcgc acagggttga ggtgtagcgc ttgggcagcc agagcagccc
    17701 accctgcacg gcgtcgagca ccaggggagc cagggcgcgt ggcgacgcct atcgtcggta
    17761 gagggctctc tgagcaccga actgaacagg taggcgagag gccagacaca gcacggcccg
    17821 ggagttggct cgccgatcac ctcaacctct ctacgctgga gcaccatgag gaaggtcgcc
    17881 atcgtcggct gcggaggcag tggcaagtcc cacttggctc gcgagctggg caggatcctc
    17941 gacgccccgg tgacgcacct ggacgccgcg ttctacgacg acaggtggaa cgcgttgccc
    18001 atagacaagt tcacagacgt gcagcgcgag ctggtggcgc agcctcggtg ggtgatcgac
    18061 ggcaactaca actcgacgct gcaggtacgg ctcgaagcct gcgacacggt ggtcctcatg
    18121 gacgtgtcga ccgtggcggc cctgtacggg atcttctccc ggcagatccg gcacggggct
    18181 ggccacaagg gcaacggagt gcacaaccgc attcactggg gcgtgatcaa gtacgtcgcc
    18241 acgtaccggc gcaggatgcg gccccgtgtg atggcgaaga tcgaggagtt ccgctccggc
    18301 accgacgtgg tgctcctggc caaccggcgc caggcgcacc gctggctgcg gaaggtcgcc
    18361 gccgagcagt cttgaacggc ccgcgccccc tgtccggggg cgcggcgtga atgagcccga
    18421 ctgtcgactt caagaacagt gagcccgcgc gaaccctccg ccagccggaa tcgtgggggc
    18481 gattgccgcg cacttcaagc tcacgagctt ccggccagcg aagtttgcga ctggcaatag
    18541 ctcaagcgag ggctgctcgt cggggggcgt caggccagat tgcccgaatg tctctttttg
    18601 ggccattttc ccgattcgta accaaccgca cgtctggttt tgggtgtgag gtatctcgaa
    18661 ttgacgacga gctggccgct tggcccacgt gtgggggtgt gcgcagcgat tgacaaaatg
    18721 ccacgtcaaa gccttgatca atcttcagta gtggtctttt ctcggtttgc tccgaagcgt
    18781 gagcgctact gctataccga ccgctagcca ggttttggtc aagatccgct cagtgtttcg
    18841 cgtactgtcc aagaagttcc cgaaacctcc ggcgaggcga gtggcgagag cgttgctcat
    18901 tcgctacagc gacacatggg catcgatgtg gtgctggttc ggttgggttg cggtggtgtc
    18961 gcaccggagg cgcccgaagg gcgacaccgc gcgccgggcc tgcgtggagg gaaccgagag
    19021 tcagcggcgc ggtcgcgcct agctcggggg agctaactgg tagaagggat ttgtcatgtg
    19081 gtctgggaag atccttcgca ctgagcccac ggggccggct cggggcggag agcctcagag
    19141 gggactgggc cgccgtcggg cggtggagag ggacctgcat cgcttcctcc gtcgggagct
    19201 gcaggacctc ggtgttcatc cgccgttgga cgtggagcag ctgtgctcgg cgctcagccg
    19261 tcggcgcggg cggccccttt acctgcggga ggcgccgctg ccgaagcccg gcccgacggg
    19321 gatgtgggtc gagtacgacg cctatgacgt gatcttgtac cagcaggaga cgacccgtct
    19381 gcatcaagat cacatcaagc tccacgagat agggcacatc ctcgtggcgg aggccgagga
    19441 cgccgagcag gcgtcggccg aagcgacggg gcggcccccc gtgctcgacc ccgacgagga
    19501 gtcggcgttc ttcgtggagg gttgggccgc catgctgccg gtcttcgacc ccgagacgat
    19561 caagcgggtc gcgcgccggt gcacgtacga cgacggcgag gagtgctccg tcgaactcgc
    19621 ggcgacgatc atcctggagt gggcgtcggt gctggacgac tccactcctc tctcggagga
    19681 cccgtcgctg cggcgtgtgc agtcggccct cggcgaccgg cggggatggc tgtaacccgt
    19741 ggaactgcta ctcctggggc tcgtgggcgc ccttgcctgg aagctctaca aactgtggcg
    19801 agctccccat gacgcgcctc tgcggtcggt gactctctgc ctgctctgcg ccacgctgtc
    19861 ctatcccatc gctatgccgg gtggcacgac cggcgtcgac acggttgcgg ggcacggggc
    19921 ggcgaagttg gtccagaacg tactgctgct cttcgcgatg tacttcctga tgtgcttcta
    19981 cctctactcg gccgccgacg cggaggcgag ccgtcgcagg gcacgcacgg aggcggtcgt
    20041 cgtcggggcc gtcgtggtgg tcatcaccct ggctgccgta tcggtgccgc acgaggtctt
    20101 cgccggcagt ttcagcaccg cggacatgac gatcccgcag atcgccgtct tttacggcgg
    20161 agccgggtgc tacctgacgt acgtcctggg cctcgccgct cggtggaccc gcacctacgc
    20221 ccgcatgtcc cgtcgccccc atgcaacagg actgtggatg gcggccgttg gcctgggtac
    20281 gatggccgtg gcctgtgcga cccgggctgt catcgtcgcc gttcgctggt tcgagatcga
    20341 cgtaccccag cgcctgatgg ctgccgtcgc gttcctgttg gtcgcatcca tccttctgtt
    20401 cacggctggc atcacctaca cgggagtccg cgcccgaata tcttcttcga agctctggct
    20461 ccagcaccga cgtgattacc gccgcctcgc cgccctctgg gagctgttgg ctgaggcgtt
    20521 ccccgacagc gtgctgccgc cagcatcatc gtccgctcat gaccgacggc gtgctcgggg
    20581 agttcaccgg cgttaccacc gccgcatcgt ggagatccgg gacggcctgg tcgccatcag
    20641 tccgtacctc ctggaggacg agaccggcat cggatcgccc gacgtcgact cggtagagct
    20701 ggcagcccgg ctccgccgcg cttccgtccg gatcaaggtg ggagctctcg caccccgccg
    20761 ggcggtcccc cttgccatgg ccctggggag cgaccgagcg gcagatgtga aacaactgat
    20821 tgcggtgtcc gacgcgctgg tgacagaccg cgcgaacccc ctcacgatca aggaggcacc
    20881 atgctgatca gcggacgacg tgtgctcgtc gacacgggca cgtatctgga cgacggcgcc
    20941 gtcctgatcg agggcgactc gatcgtggct gtggggccgc gcaaggagat cgaggagcag
    21001 accgccgccg acgtgccgcg gtcggtgttc gacggcaccc ttctgcccgg gttgatcgac
    21061 gcccacgtac acctcatctt cgacgggggt cccgacccgg tgtccgctct ccaggacccg
    21121 acggatgagg ccctgctcgc ggacatgcgc cgacgcgcgg gggaactgct gctcagcggc
    21181 gtcaccacgg cccgtgacct cggagaccgg aacgggcttg cacttcgcct ggatgcggag
    21241 atcgccgccc atcgcacgcc gggaccgagg atcgtctccg caggcacgcc cctgaccacc
    21301 cccggtgggc actgccactt cctcggcggt gaggtttcgg gcgaagccga gatccgcgcc
    21361 ctcgtccgcc tcaacctcga acgaggcgct ggggtcatca aatgcatggt cactggtggc
    21421 ggcctcaccc gtggcgggcc ggcaagccac gaatcccagt tctccgcaac ggaactgcga
    21481 cttctcgtgg atgaggctca cgcggcaggc gtgcccgtcg cagcccacgc gcacggagcc
    21541 gacggcatcg cagcagccgt ggatgccgga gtggacacca tcgagcactg cacgtggatg
    21601 accggcgacg gcctcgactt ccgccgggac gtggtgcagc agatcatcga ccgcgacatc
    21661 accgtctgcc cagcggtaag cccccactgg cggatgctcc ccgcgatctt cggcgaggag
    21721 cgcgccgccg cgatgttcga cctggtacgc cagatggcag acgcgggtgt gaagctgatc
    21781 gccggcacgg acgccggagt gcagcgcgcc aacttcagcg gcctggtacc tgccctctcg
    21841 ttctacgccc acctcggcct ggcgaacgcc gagatcatcg acatggcgac gaccgcagca
    21901 gccacagccc tggggctcgg ctccacaacg ggccgcattg ctccgggcta ccgagcggat
    21961 ctcatcgttg tcgacgggga cccgctctcg gatctcgacg ccctcaagaa catcaaggcc
    22021 gtattcgcct ccggcgggcg acacgagccc aacgcaccag cggagtagtc ggtgctgacc
    22081 gagccctgct ctcccggagc ctcaagcgcc ccggagggca gggccctact cggcgtcttc
    22141 ggagccgacc tgtttctcga actcggtctc aaggtccgtc aggagcgaga gaacctcggg
    22201 cgacagaccc tccgggccga ggccgcgggc ccgaacccgt ctgatccccc cgttcttgga
    22261 ggccagcaac acacgaatcc cctggtacac ctggcgggcg acggcgtcgt ccggctcgaa
    22321 gtacatgcgc tcgacgccga agaactcggc aaggccctcc aggacaaccg ggggagggct
    22381 gtcggcctcg ccagtacctg ttcggagggc ctcaacctca ttggccgtga caacctctga
    22441 ccctgcatgc cggttcaccg cctccgcgat ctcctcgtcc cctggagccg cgcccgcagg
    22501 gtaggactgc tccaacagga agctgatctt ctccccgagc gtacggggag actcctcggc
    22561 ctcggcgccg gcgacgctct cgtccccggc ttcttcgacg gtgttcccga acgagcgctc
    22621 ctgagcctgc tccagcaccc tttccgatac gccgtacgcc gctgccagct tcggcacgta
    22681 cttctccttg agccgccgta cgccgttctc ggccgcagcc accgggccgt cgctcttcgt
    22741 gccgatgaac ctcgccacct cgtaccggta gaggcccgcg tcgcatcgca agtcgatcag
    22801 gtcgggtgtg cccttacggg ggaacagctc atccaacggt ttccgaagta cacgcgcgat
    22861 gcccggcagc ttctcctggt ccgggacgct tgagcccaac tcccatcccg ccacggttga
    22921 gtccgcagcg tcgacggcag cgcccacctc ggcctgcggg atctctgcag cccgtcgtac
    22981 ggcgcgcacc actgttctgt cgaagtggcg agctggcatc gagacctctt tttcgtgcga
    23041 gtcgaagaac tgtcggctcg ttgacctttc gcgcgaaccg ggatagcttc agactaccga
    23101 aaaacgggat gccgtgcatc cctctccgtg gcaaggctgt gtgcctgccg aggacgtgag
    23161 gctgaggagg agaacacctc cttcgctgcg cccggcaaga ggggcgccgg ccgaacgcag
    23221 gtcagggagg ggcgagggat gcacgccagc ggcccgtaac tcgacgaagc aacgaaaaac
    23281 cggcgcccgg gagttaccag ctcccaagcg ccgggccggc accccgaagg gcgccgatgc
    23341 acatctcgcg ggcggcgggg cttttgcacg agaaccaccg caccgcagtc ctacaaacca
    23401 cggagtatcg catgcctgcc atgccgagcg gaaccccggc ctgcccggac accagccgtc
    23461 gaggccgcct cgccgcccaa ctcgccgaca tgatctccgg cgcagccacc atccgggtca
    23521 gcctcaccga cccgacgcat gtctggccgc acccgcacac agtcgtgcag gacgagacgg
    23581 gcaagacgat ggagctgggc cggacggcgt ccagggtcgc cgcccgctgg atcctgaggg
    23641 tctggccgga caaagactgg acccgcccgc acaccttccg cctcgccgac gccaccctca
    23701 cccgcagcga cttgaccgcc gccgagcggg gccgctgaga tggcccggat ccgaaccatc
    23761 aagccggagg cgttcacgtc cgagtctctc gctgaggtga acgtcgcggc cgagcggacc
    23821 ttcttcggcc tgctcaccca ggccgacgac catggtcgtc accgggacaa cgccgcgatc
    23881 atcgcggggc tcctctggcc cttgcgcgcc gaacacacct cggtccacgt cgaggacgac
    23941 ctccaccagc tcgcgaacgc cggactgatc tgccggtaca ccggatgcga cggccgccgc
    24001 tatctccaca tcgtgacctg gtccgagcac cagaagatcg acaagccgag ccagtcgcgc
    24061 ctgccctcgt gcccgcagca ccaggctgcc gaccggtgcg caccgtgcaa gggctcctgc
    24121 acccgcgagg gtccgtccac tcctcctcga ggactcgccg aaacgtcggg gaggacttcc
    24181 cgagccctcg atctgcccgc cgtgcccacc tcggcgacgc cggaccatgc aggcgggccc
    24241 accgccgacc agcaggaggc tgccgacgga accatcagcg caccggggcg gggcggagcc
    24301 aagagcgcag gtcagaggac attctccgag ggctccccga accttccccg aagccgctcc
    24361 gagggctcgg cgcctggatc taggatcttg gatcctggat ctcttgtccc tacggggcgc
    24421 acagcgcccg cacccagcgt ctccgccaag gatctcgtcg gcgagtacgt cgccgggtgc
    24481 gaccggcgcc ccccgaacga cgtgatcgga cacctcgggc ggatcaccaa gaagctcctt
    24541 gacgaaggca tcgcaccgga ccacatccga gccggactgg ctaactacgc ggccaacccg
    24601 aagcacccga gcgtgttgac cagcatggtc aacgaagcga tgaacgctcg ccccggcggt
    24661 ttggcgcggc cgggaatccg gcctaacgtg cccgcccacc aggcgtggac caacccggcc
    24721 aacgcttctg ccgcctacgc cgaggagctg tgatgcacac ccgtcaccgc gaaccccagc
    24781 tcctcggcaa cgaagccacg ctggagcgca tggcccggat cctggccgcc cgcaacatcg
    24841 acccggccga cgccgcgctg ccggacgacg ccgagccctt ctcaccgctg gacgctctgc
    24901 tcgccgggat gcccccgcgc tatcaagcgg ctgtcgccga ccaccccacg gtcctggagt
    24961 gggtccggaa ggtcaccgac gcggccgtcg cccccagccg aggagcccga cgacaggtca
    25021 ccaccggccc tagcttgctg atggccgggg tcgtcggcgc gggcaagacg caccaggcgt
    25081 acggcgcggt ccgagcgctg gtgcagagcg gggtcggcgc gcgctggcgg gcgaccaccg
    25141 ccgccgacct ctacgccgat ctccgccccc ggcccggggt ggacagtgag cgggagctgg
    25201 cggccgtcag ccgttgccct ctgctgatca tcgacgacct cggcgcggcc aaggcgagcg
    25261 agtgggtcga ggagatcacg taccggctga tcaaccggcg gtacaactac gaactcccca
    25321 cgctgatcac gaccaacctg gcgatcaagg acctgcgttc ctacctcggg gaccgagtcg
    25381 ccagcaggct cgcgcagatg accacccgag tcgagttcga ggccgtcgac cgcagacgcc
    25441 acagcgccgc cgcctgaccc tccacaggcc accccgccgg accgcgccct cgcaccgccg
    25501 tccccgggca cctaccgcca gcgcacctct ccgccgacgc ccctgcgcgc ggagagcgat
    25561 cggagccccc cgcatgacca gcacgatgaa cggccccgcc cagcaccgtc agctcggcga
    25621 ccagacctgg caggctgacg ccgtctgcca gagcaccgag tacaacccgg tggaccccga
    25681 agtcttcttc cccgaacccg acgagaccgc caagatcgcc acggccaagg ccctgtgcgg
    25741 ccagtgcccg gtccggcgca cctgcctgga cgccgctctc gaagggggtg acaccgacgg
    25801 gatccgtggc ggcctgacgg aggaggagcg cgggccgctg cacgacaagc tcgccagccg
    25861 cctcgactac agccgcgtca atgccaccat cgccggacgc gacgtgcacc tcacccatac
    25921 ggagcgccgc gcggtcgagt acgcggccta ccgccacgga gtgagcgagc agcgcctggc
    25981 ctggcttctg aaggtcaccg aggagcacgc caagaagcgg taccgcgaga tccgccgggc
    26041 cgagcgcaac cgaaccctga accagcccac cacgaacacc acaccccccg agaccagcgg
    26101 cgagcgcctg atccgcgacg acttcgggac ggcggcatga acatcgcaag cgcgtcgaag
    26161 acggcgcaca tatccgggtg ggaccgcgcg gctgtcgtgg cgctcggggg cgcggggtgc
    26221 gcgctgtcgt acgacgccct gcagcagatg gccgtggcca tccacatccg aggcttcctt
    26281 acctacctgt tccccctggt gatcgacggg ttcatcgcct acggcatccg agccctcctg
    26341 gtcctgcgca acgcaccact gcgcgcccgg ctctacgtct ggacgctctt cggcacggcc
    26401 accgccgcca gcatctgggc caacgcactc cacgcggtgc gcatcaacc
//
