LOCUS       NZ_KZ819178            22606 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. CS131 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ819178
VERSION     NZ_KZ819178.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS131
  ORGANISM  Streptomyces sp. CS131
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7968990)
  AUTHORS   Malmierca,M., Ceniceros,A., Mendez,C., Salas,J.A. and Olano,C.
  TITLE     Genome analysis of twelve Streptomyces spp. associated with Peruvian
            leafcutter ants
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7968990)
  AUTHORS   Malmierca,M., Ceniceros,A., Mendez,C., Salas,J.A. and Olano,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2018) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 88.88x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003116755.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 09:38:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,994
            CDSs (total)                      :: 6,912
            Genes (coding)                    :: 6,769
            CDSs (with protein)               :: 6,769
            Genes (RNA)                       :: 82
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 41 of 143
            Pseudo Genes (incomplete)         :: 122 of 143
            Pseudo Genes (internal stop)      :: 12 of 143
            Pseudo Genes (multiple problems)  :: 31 of 143
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:40:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3319179
            Orig. end                         :: 3341785
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ819178.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Professor JA Salas
            laboratory.
FEATURES             Location/Qualifiers
     region          1..22606
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="16"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22606
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22606
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12606](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12606
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(806..1681)
                     /locus_tag="DBP20_RS14905"
                     /old_locus_tag="DBP20_14905"
     CDS             complement(806..1681)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1214:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063962.1"
                     /locus_tag="DBP20_RS14905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14905"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_109179045.1"
                     /transl_table=11
                     /translation="MKFTSRAVVLPLAALYFLVPIGASIWFSVNEVEGVSFDAYTQGLG
                     TEGLTTSLMLSVRLGLATIVCGLLLMVPTLVAVALYLPGLRRTVEILCMMPLVVPPIAL
                     VAGVTTVLSWEQDLADTPFYMTFRMLRDESFPLVLVLVYTVMSLPFLYRSLDAGLRSVD
                     LRTLVEAARSLGASRLQTLWQVIVPNLRTAVVGGAVLSLAMVLGEYTVASVLSYRPFSV
                     WMVEIKDSEAQLSVAAAMLSLLITWGLLLLLTTLAGGRRTPRTPLDSGREDGQDRQDRE
                     SRDNRKKTVS"
     gene            complement(1678..2640)
                     /locus_tag="DBP20_RS14910"
                     /old_locus_tag="DBP20_14910"
     CDS             complement(1678..2640)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010071150.1"
                     /locus_tag="DBP20_RS14910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14910"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_204163064.1"
                     /transl_table=11
                     /translation="MPDQTALPAPATGSVPVAGAAAPVPPAPDVRDGGTAPRRRGGRRH
                     RWPVVVPFFAFLAVCFGLPAGTMVYGAFTVLDPESGASRLSTENVSGSLSGAYATGLTG
                     SVELSLVTALLATVIGTLIAQAVVTSPRPALRGIVVSASGVLANFSGAPLAFAFIATLG
                     TTGTVTQLLHLDRTGFSLYSFTGLVLAYLYFMVPLMVVTVLPALDGLRSQWQEAAASCG
                     ATRGQYWRHVGIPVLTPSLLGGAVLMFGTAFASHATAAVMVGSSQPLITIQIANALNGN
                     VLVGQENLALAMSLNMVVIALLVMAVQIPLQRRSARWLG"
     gene            complement(2643..3791)
                     /locus_tag="DBP20_RS14915"
                     /old_locus_tag="DBP20_14915"
     CDS             complement(2643..3791)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063966.1"
                     /locus_tag="DBP20_RS14915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14915"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_109179046.1"
                     /transl_table=11
                     /translation="MKAHHPRRVLTAAALVGLTALVATGCGSAPDSAGGQNSKAAKAES
                     AADLGGMEKLVAAAEKEGKLNVYALAPDWANYGEMIAAFEKKYAVEVNNEDPGGSSQGA
                     LNAAAKRKGQDRAVDALDLGTSYMQEAGKKGLLAPYKVKGWGDIPDAQKQPDASFMNNY
                     GGYISIGCDAKAVKNCPETFKDLLKPEYRNKVALNGDPTESSSALAAVIAASLANGGSL
                     DDAQPGLDFFQELRKKGNFVPAKSTLATIQQGETPISIDWDYLNLGYGQKLEPKGVDWQ
                     VVVPADGLYSRYYNQGVNKYAPHPAAARLWLEFIYSPEGQNIWLKGFSRPALLEAMKKD
                     GSADKAAVARIPEVHGTPQEPTAEQEAKAKETVVQGWGKAVS"
     misc_feature    complement(3893..3909)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.6"
                     /tool="antismash"
     gene            4093..4833
                     /locus_tag="DBP20_RS14920"
                     /old_locus_tag="DBP20_14920"
     CDS             4093..4833
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063967.1"
                     /locus_tag="DBP20_RS14920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14920"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_032766649.1"
                     /transl_table=11
                     /translation="MTRRHQQIAEELRLAIADGTYPVGSELPSESELALAHGVSRGTLR
                     QAFGTLQSEGLIGSRQGARRTVLSTTPSQSFAELRSFAQWARAGGRTPGGLVLGSRRAK
                     ATEAEAAQLHLTPGDAVLHVLRVRTLDGEPALLERTVYAGWVAAAVERLPDDCESVTQS
                     LYDEAGVAMSHGEHHLDAVAAGTTDARELAVRRGAPLLRVRRTTTTPDGRPVETSDDRY
                     KPDSVVFTVRNSVQANPLVRTAPD"
     gene            4922..5608
                     /locus_tag="DBP20_RS14925"
                     /old_locus_tag="DBP20_14925"
     CDS             4922..5608
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006125437.1"
                     /locus_tag="DBP20_RS14925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14925"
                     /product="HAD family phosphatase"
                     /protein_id="WP_109179047.1"
                     /sec_met_domain="HAD_2 (E-value: 2.4e-22, bitscore: 78.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPLPQHAQLPQVPPLPRPAALLCDMDGTLVDTEHAWLDTVAGFL
                     RTQGSPADAGTLAPFAGAALADAADRLVREGLTALSPAQALARLDREFTARVAAGVAVQ
                     PGALRLLDRARALGVPTALVTASERHVADLVLDTLGRHRFDTSVASGETERGKPHPDPY
                     LAAAAALGVAAPDCLAVEDTPTGAAAALAAGCRLLAVPSVPGIEPGPRTVLVTSLTEAD
                     LADTAV"
     gene            complement(5626..6819)
                     /locus_tag="DBP20_RS14930"
                     /old_locus_tag="DBP20_14930"
     CDS             complement(5626..6819)
                     /EC_number="6.5.1.8"
                     /GO_function="GO:0008452 - RNA ligase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577624.1"
                     /locus_tag="DBP20_RS14930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14930"
                     /product="RtcB family protein"
                     /protein_id="WP_109179048.1"
                     /transl_table=11
                     /translation="MSYVEVPGAKVPIRMWTDPASVEDVAMQQLRNVSTLPWIKGLAVM
                     PDVHFGKGATVGSVIAMQGAVCPAAVGVDIGCGMSAVRTSLTANDLPGDLSRLRSKIEQ
                     AIPVGRGMHGDAVDPGRLHGFPTAGWDDFWGRFGGIAEAVKFRQERATKQMGTLGSGNH
                     FIEFCLDETGSVWLMLHSGSRNIGKELADFHIGQAQKLPHNQGLIDRDLAVFVADTPQM
                     AAYRNDLFWAQEYAKFNRAIMMGLFQDVVRKEFKKARVTFEPVISCHHNYVAEERYEGM
                     DLLVTRKGAIRAGSGDYGIIPGSMGTGSYIVKGLGNEKSFNSASHGAGRRMSRNAAKKR
                     FSTKDLEEQTQGVECRKDSGVVDEIPAAYKPIDQVMEQQRDLVEVVAKLKQVVCVKG"
     misc_feature    complement(6852..6865)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     18.25"
                     /tool="antismash"
     misc_feature    complement(6932..6941)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            6992..7852
                     /locus_tag="DBP20_RS14935"
                     /old_locus_tag="DBP20_14935"
     CDS             6992..7852
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003968382.1"
                     /locus_tag="DBP20_RS14935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14935"
                     /product="hypothetical protein"
                     /protein_id="WP_109179049.1"
                     /transl_table=11
                     /translation="MAYVPGVALLAALAVGCSAGADSDANGTDSKAGTPAVTPAPPGKY
                     LTLPAPCRAVPRSTLKDLLPGAAELPGDQQDKVFRGSAAVTYDTDRKVGCSWKADGPNA
                     TRSLSIDLERVVSYDPAVSDDDRADTVYAKKEKAAGLSASAPPGPPDEKDKKGEASEGS
                     GKAKDPADADATDSADPSPSGGDDANSGESTGGTPGSSSSPEEALPSRILDDLGDAAFL
                     QDLPKKAGSTAQHHTVSVVFRTSNVVVTVRYAEQPALVTQVPDGKELQEKAQALARKLA
                     DTLSE"
     gene            8046..8837
                     /locus_tag="DBP20_RS14940"
                     /old_locus_tag="DBP20_14940"
     CDS             8046..8837
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489236.1"
                     /locus_tag="DBP20_RS14940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14940"
                     /product="DUF3558 domain-containing protein"
                     /protein_id="WP_109179050.1"
                     /transl_table=11
                     /translation="MHRSAPRLSRILACAAVPVMLVAVGCSSDSGSDGKKNAGSSSSGT
                     AGSKSPEPTVEPAKFADLPDPCTSIGKKTIEDLVPDAKKKGGTAGGSTDLSVRSSCSWN
                     GLDDQGVKGSQYRWMDVGFTRFDSDQSLGSGAKRATADYTKQVTKAKGSEGAEKVAAEP
                     AAGIGDEATLVTYGLSKTDEDFVYATVVARTGNVVVTLTYNGAGYAGAKTPSSSDIVKG
                     AQKAAGEAVAAVGKTAGSGGADEDSGKGSDKGESSAKPKSS"
     gene            9020..9706
                     /locus_tag="DBP20_RS14945"
                     /old_locus_tag="DBP20_14945"
     CDS             9020..9706
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007460369.1"
                     /locus_tag="DBP20_RS14945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14945"
                     /product="hypothetical protein"
                     /protein_id="WP_109179051.1"
                     /transl_table=11
                     /translation="MRNRIAFAAALTTGLVALTATAATAAPAKPGTAASGDTRACGDVK
                     LSGALPVPPEGMAVRQDVSIGPDCEPVLGPARLVAKAGPAATARTARAAAQGDRQVRSW
                     SEMYDCCNIRMTGLYTTSDWSSDGTVVTASSTEATQQWNREPWNAGWSLKSSGTSADCV
                     ANCAVSTNVADASFTYKGIFDLTGNVYANTHRSTVALKADGTASCEFEVDLKNTFIGWN
                     WQRGCE"
     misc_feature    complement(9842..9856)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.32"
                     /tool="antismash"
     misc_feature    complement(9843..9858)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            10001..11809
                     /locus_tag="DBP20_RS14950"
                     /old_locus_tag="DBP20_14950"
     CDS             10001..11809
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="DBP20_RS14950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14950"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_093439000.1"
                     /sec_met_domain="Asn_synthase (E-value: 1e-28, bitscore:
                     99.7, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHGTPHFLAFPDRDDAAAVVRRLRSAHPGLKSVDHPSGRPWILG
                     SWDDEDLAVARAGHDSVALIGTLPRLGGALQDLAARMNGSAAALDTLPSVLPGDFHVLG
                     SVAGALHVQGTAYGTRRVYHGRVDGTVVASDRALRLAELVGASIDMSALAWKLLLPVPR
                     HLDGRTMWLGIDAVEPGLRLVVGAGDERVRTVRRHRPPESRLRMAEGAAAVREALVSSV
                     RARTHRGGLMSSDLSGGLDSTSLSSIAAGQLGEGEFIVCTNGGDESINEDGHWARVAAS
                     AWPHVEHYQLPPEEQPLFYSGALDTACQSDFPGMIAVSRKRATILMSRMAERGSRLHMG
                     GQGGDHLFFSSGSHYYSLLTRRPVLSLQRIRAYGILYGWSWTTVLRQLSNRGSYRSSLA
                     AIDLDGSGDLGFSAPGLNWVRQPVVPSWLTADCRELLAKELARVVAEAEPRSPVVSRHL
                     ELDNLLTTTLDMASTCDASRLAGVPLSMPYFDEAVVDAALSVRVEDRATPYAYKPLLME
                     AMRGILPDACRARTSKAEGSFDAVGGLYRHRAELIELWQESALGKAGLIDAARLADLCS
                     RPGTPDLKDGSINSTLSCEVWLRSVA"
     gene            11870..12127
                     /locus_tag="DBP20_RS14955"
                     /old_locus_tag="DBP20_14955"
     CDS             11870..12127
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007460374.1"
                     /locus_tag="DBP20_RS14955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14955"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_065486978.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 3e-26,
                     bitscore: 89.9, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.2e-13, bitscore: 48.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLRNRKHLVVTDTDYGAVLLDTKSGQYWQLNPPGAVIVRTLLDG
                     EGPDEAIRRVTDRFDVETERATTDVHALIEAMRSAGVVEK"
     aSDomain        11876..12121
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DBP20_RS14955_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.20E-28"
                     /identifier="RREFam002.1"
                     /label="DBP20_RS14955"
                     /locus_tag="DBP20_RS14955"
                     /protein_end="84"
                     /protein_start="2"
                     /score="89.9"
                     /tool="antismash"
                     /translation="LRNRKHLVVTDTDYGAVLLDTKSGQYWQLNPPGAVIVRTLLDGEG
                     PDEAIRRVTDRFDVETERATTDVHALIEAMRSAGVVE"
     gene            12124..12606
                     /locus_tag="DBP20_RS14960"
                     /old_locus_tag="DBP20_14960"
     CDS             12124..12606
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047207.1"
                     /locus_tag="DBP20_RS14960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14960"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_109179052.1"
                     /sec_met_domain="PF13471 (E-value: 6.3e-23, bitscore: 79.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVTVALNRDHRPRSWKLRLQTRLAICLARILALFKPYVVRRVLV
                     RLSKGAKAADAAEITTARDSVLASSLGLHGLRACLPRSLATALLCRFRGAWPTWCVGVR
                     TAPPFAAHAWVEAGREMIGETGGYDSYSRLFTVPPTTPLPLAENEPATEDEPAPDQ"
     gene            12882..14279
                     /locus_tag="DBP20_RS14965"
                     /old_locus_tag="DBP20_14965"
     CDS             12882..14279
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006125442.1"
                     /locus_tag="DBP20_RS14965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14965"
                     /product="DUF2637 domain-containing protein"
                     /protein_id="WP_109179053.1"
                     /transl_table=11
                     /translation="MAAMQLTRTHRILIGVVVAGAVVIAAIGFAGSYAAVRELAEEKGF
                     GTFSLVFPIGIDAGICVLLALDLLLTWMRIPFPMLRQTAWLLTAATIAFNGAASWPDPL
                     GTAMHAVIPVLFVVSVEAARHAVGRIADITADKHMEGVRLTRWLLSPIPTFKLWRRMKL
                     WELRSYEQVIKLEQDRLIYQARLQARFGRNWRRKAPVESMMPLRLAKYGVPLAETAPAG
                     LAAAGIEPALLPPVPVEADRPKAELSPAGPDRAAEPVHAELPYGPQPSAEHGQQKARPE
                     HAHPHPQQQQPQPHQQQQPLSLQKQDPPVPPTHDSPWFAAQKLPDNGHESAYDPQYVEG
                     PEPGPVQIPAGPGRTRPLGDVGTIGAVPHPRQEEQAPEPPEVPDPEEAPQVEQWPMEDT
                     DFAREAYEVFSEYTDAQGQYPSVEVLDIHLADTRNVRHPRSTELLQQLMSQFREAYAQR
                     PTAEQPA"
     gene            complement(14359..16125)
                     /gene="lysS"
                     /locus_tag="DBP20_RS14970"
                     /old_locus_tag="DBP20_14970"
     CDS             complement(14359..16125)
                     /EC_number="6.1.1.6"
                     /GO_component="GO:0017101 - aminoacyl-tRNA synthetase
                     multienzyme complex [Evidence IEA]"
                     /GO_function="GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lysS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380410.1"
                     /locus_tag="DBP20_RS14970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14970"
                     /product="lysine--tRNA ligase"
                     /protein_id="WP_032783010.1"
                     /transl_table=11
                     /translation="MPTVAESQTSTETDWVSRFADDVIAESERRAPGKPVVVASGLSPS
                     GPIHLGNLREVMTPHLVADEIRRRGYTVRHLISWDDYDRYRKVPNGVPGVDASWAEHIG
                     KPLTSVPAPAGSAYPNWAEHFKAAMTAALDELGVEYDGISQTEQYTAGTYREQILHAMK
                     HRADIDAVLDRYRTKKDPAAAQGKGGKKPQQQKKVDEAELEAAEGSGAADEDDGSGNSA
                     GYFPYKPYCGNCEKDLTVVTSYDDDTTELNYTCSACGFAETVRLGEFNRGKLVWKVDWP
                     MRWAYEGVIFEPSGVDHSSPGSSFVVGGQIVREVFDGVQPIGPMYAFVGISGMAKMSSS
                     KGGVPTPADALKIMEAPLLRWLYARRKPNQSFKIAFDQEIQRLYDEWDSLGRKVADGTV
                     LPADAAAYSRAVRTAAGELPSTPRPLPYRTLASVADITAGAEDQTLRILSELDPENPLT
                     SLDEARPRLDRAENWITTQVPAEARTIVRDEPDKELLGSLDDRGRESLRLLLEGLDTHW
                     SLDGLTTLVYGVPKVLAGLEPDAKPTPELKAAQRSFFALLYRLLVSRDTGPRLPTLLLA
                     VGADRVRRLLGA"
     gene            16261..18033
                     /gene="argS"
                     /locus_tag="DBP20_RS14975"
                     /old_locus_tag="DBP20_14975"
     CDS             16261..18033
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003968363.1"
                     /locus_tag="DBP20_RS14975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14975"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_109179054.1"
                     /transl_table=11
                     /translation="MASVPSLASTLQQQLADALTAALPDAGTADPLLRRSDRADFQANG
                     ILALAKKLKGNPRELAGQVTAALPAGELIKDIEVSGPGFLNITLADRAIVETLAARAAD
                     TEGRLGVPVAADAGKTVIDYAQPNVAKEMHVGHLRSAVIGDAMVRILEFTGEDVVRRHH
                     IGDWGTQFGMLIQYLIEHPGALKHEGGASDGEAAMSTLNRVYKASRALFDSDEEFKARS
                     RDRVVALQAGDAETLELWQGFVDESKIYFHSVFDKLDMEVRDPDIVGESGYNDMLEETC
                     RILEETGVAVRSEGALCVFFDDVKGPDGNKVPLIVKKTNGGYGYAATDLSAIRNRVQDL
                     KADTLLYVVDARQSLHFKMVFETARRAGWLGDGVKAVQLAFGTVLGKDGKPFKTREGTT
                     VRLEDLLDEAVARATAVVREKAGKVGLSEEEIVGNGRYVGIGAVKYADLSTSAVRDYKF
                     DLDQMVSLNGDTSVYLQYAYARIQSILRKAGDAVPAAHPELALAPAERALGLHLDQFGE
                     VLAEVAAGYEPHKLAAYLYQLASHLTTFYDQCQVLSPDNAPEVVENRLFLVELTARTLH
                     QGMALLGIRTPERL"
     gene            complement(18112..18459)
                     /locus_tag="DBP20_RS14980"
                     /old_locus_tag="DBP20_14980"
     CDS             complement(18112..18459)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459068.1"
                     /locus_tag="DBP20_RS14980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14980"
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="WP_088576849.1"
                     /transl_table=11
                     /translation="MTTESALAPDSSVTFINVFEIAADELDAFVGKWEQRARLMRDKPG
                     FIDSRMHRARSSDSRFQLVNVSHWESQEAWEAATADPDFASRTRAAREETKQPVTPNPA
                     VYDVVVELTAP"
     misc_feature    complement(18439..18441)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18488..18928)
                     /locus_tag="DBP20_RS14985"
                     /old_locus_tag="DBP20_14985"
     CDS             complement(18488..18928)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019767145.1"
                     /locus_tag="DBP20_RS14985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14985"
                     /product="hypothetical protein"
                     /protein_id="WP_032766635.1"
                     /transl_table=11
                     /translation="MSATAETSPAPSAAVITEPLPDLQLQLLIQLLDEEPRSSLPLTLT
                     HPGGILHGDVIGHEQWKAEWARSLRQVEGEGANLLAEFPETVDQGVRELRAEEDETGAA
                     RLPRWIHLRDVTLVSGAAAPVSLPLWRGRLSDVSGWALGRPQ"
     gene            complement(19024..20235)
                     /locus_tag="DBP20_RS14990"
                     /old_locus_tag="DBP20_14990"
     CDS             complement(19024..20235)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003968360.1"
                     /locus_tag="DBP20_RS14990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14990"
                     /product="phospholipase D-like domain-containing protein"
                     /protein_id="WP_109179055.1"
                     /transl_table=11
                     /translation="MSATAADASDRTAPEDRTCEERSERLRRRLERLIGIAATEGNSLV
                     PLRNGDAIFGAMLKAIREAEHTVDLMTFVYWRGDIALQFAEALADRARAGVRVRLMLDG
                     FGSRLIEKDQLAMMDEAGVTVTWFRKPLYLSPLKQNHRCHRKVLVVDEQTAFTGGVGIA
                     EEWCGDARNEHEWRDTHVQLTGPAVDGLAAAFAQNWAECHDELFDERDRFISEEHHGDS
                     VVQVVRGSASFGWQDMQTLIRVVLESAEERIRLTTAYFAPDAYFTGLLCDAAARGVEVE
                     ILLPGPHTDKRVCQLAGQRYYEDLTACGVKIHQYQPTMMHTKTLTVDRVASLIGSTNFN
                     RRSLDHDEEVMLAVLDQDFTATLDGHFEDDRAKSVLIERGRWKRRDLLQRAKEAAVMPI
                     RRFL"
     misc_feature    20386..20399
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     misc_feature    complement(20396..20410)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            complement(20415..21287)
                     /locus_tag="DBP20_RS14995"
                     /old_locus_tag="DBP20_14995"
     CDS             complement(20415..21287)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380407.1"
                     /locus_tag="DBP20_RS14995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_14995"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_109179056.1"
                     /transl_table=11
                     /translation="MPPPRRPAATATVEKRVFDLLNAEILGLRLGPGEHIVTEAVAEAL
                     GVSRLPVREALRSLAGRGLVELHAHRGAFIPRLGPEDLDRIVETVEARARLEPWAAELA
                     AERHDADQLAALDRALEQGFDALDRRARPEANRAHREFLRTLTLMSGHATLIEVLEPLQ
                     YRTMLAFVSVVMTVEPEGWASHRIVRDAVADRDGAAASAELSRHLAEVLDALRVPGNVV
                     PSVIGRAAAGGRGGRRPASRRLKALRLDEGDGEGAVGGEGAVGGEGAVGGEGAVGGEGA
                     VGGGREERR"
     misc_feature    21376..21389
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            21397..22563
                     /locus_tag="DBP20_RS15000"
                     /old_locus_tag="DBP20_15000"
     CDS             21397..22563
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380406.1"
                     /locus_tag="DBP20_RS15000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_15000"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_109179057.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 8.1e-09, bitscore:
                     34.8, seeds: 790, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATLTNIEPVAAARALAPRLREHAAEADRLRTLPDATVRLLDEAR
                     LFDVLTPRELGGTGLGFDTAVLVAEELSRGCASAGWVCAVLGGTAWAVAQMDPRAREEV
                     FAGPSTRIALQLRLGGPPAERVADGYLLHGMRGRFCSGIDHADWILAGVSAPRTAGADP
                     EPHFALLPRERTEGVDDWHTSGLRGTGSRSFTTPAAPGLLVPEHRVLPLSALDPLNTSP
                     YGRPGTAPYRMAHTAVGTVALAGVLLGTARAALDAHTESAGRAPGPDALDVPALTATVD
                     AARALLLADLKALADSATPGGSREERARMRRDIAHAGTRCRAVVNAVYEASGSGVIYDD
                     APLQRIWRDANAAAQHPTFDLRRWGPPHLEAQTEVRSADITSPQETSA"
ORIGIN
        1 tcggcgccga cggcgggccg ctcgccgtgg atgggcagcc gctgcccgaa cagctcgacg
       61 accccgccgt cccggacggt gcccggcagc cggttcatgg tgccgacgaa ctcggcgacg
      121 aacggggtgg ccggccggtc gtacaactcg ccgggcgcgg cgcactgttc gagccgcccg
      181 tccttcatca cggcgacgcg gtccgccatg gacagcgcct cctcctggtc gtgggtgacg
      241 aagacggtgg tgatgccgag gtccagctgg atgcgccgga tctcctcgcg gaggctgagc
      301 cgcaccttgg cgtccagggc ggacagcggc tcgtccagga ggagcaccct ggggcggatc
      361 gccagggcgc gggcgagggc gacgcgctgc tgctggccgc cggacagctg gtgcgggtag
      421 tggccgtcgc ggccgggcag cccgaccagc tccagcaact cccccgcccg ctccttgcgt
      481 tccgcggcgc cccggccccg tacccgcagg ccgtacgcga tgttctcggc ggccgtcatg
      541 ttcgggaaca ggctgtacga ctggaacacc atgccgatgt cccggcggtt ggccggtacg
      601 gaggtgacgt cctcgccgcc catcagcagc tcgccgccgt cggcggtctc gaagcccgcg
      661 acgatgcgca gggcggtggt cttcccgcag ccggacgggc cgagcagggc gaccatctcg
      721 cccgcggcga tctccaggtc gaggccgtcg agcgcgaccg tggagccgaa cttccggcgc
      781 agttgcttga gatgcacggg gacggtcatg acacggtctt ctttcggttg tcgcggctct
      841 cgcggtcctg gcggtcctgg ccgtcctcgc ggccggagtc caggggcgta cggggcgtac
      901 ggcggccacc ggccagagtg gtgagcagga gcagcagccc ccacgtgatc agcaggctca
      961 gcatcgcggc cgccaccgag agctgcgcct cggagtcctt gatctccacc atccagacgg
     1021 agaacggccg gtaggagagc acggaggcga cggtgtactc accgagcacc atggccaggc
     1081 tgaggaccgc gccgcccacc acggcggtcc gcaggttcgg cacgatcacc tgccacaggg
     1141 tctgcaggcg ggacgcgccg agcgaacggg cggcctcgac gagcgtgcgc aggtcgacgg
     1201 agcgcagccc ggcgtcgagc gagcggtaca ggaacggcag ggacatgacc gtgtagacga
     1261 ggacgagcac cagcgggaag ctctcgtccc gcagcatccg gaaggtcatg tagaagggcg
     1321 tgtcggccag gtcctgttcc caggacagca ccgtggtcac ccccgccacc agcgcgatcg
     1381 gcgggacgac cagcggcatc atgcacagga tctcgacggt ccggcgcagc cccggcagat
     1441 agagcgcgac cgcgaccagg gtcggcacca tcagcagcag cccgcagacg atggtggcca
     1501 ggcccaggcg caccgagagc atcaggctgg tggtcagccc ctcggtgccg agcccctggg
     1561 tgtacgcgtc gaagctgacg ccctcgacct cgttgacgct gaaccagatc gaggcgccga
     1621 tgggcaccag gaaatacagc gcggcgagcg gcaggacgac ggcccgcgag gtgaacttca
     1681 tccgagccat cgggcactcc tgcgctgcag cggtatctgt acggccatca cgagcagcgc
     1741 gatcacgacc atgttgaggc tcatggcgag ggccaggttc tcctgcccca ccaggacgtt
     1801 gccgttgagc gcgttggcga tctggatggt gatcagcggc tgcgaggagc cgaccatcac
     1861 ggcggcggtg gcgtgcgagg cgaacgccgt accgaacatc agcaccgcgc cgccgagcag
     1921 cgacggcgtc agcaccggga tcccgacgtg gcgccagtac tgcccgcggg tcgccccgca
     1981 ggacgcggcg gcctcctgcc actgcgagcg cagcccgtcg agcgcgggca gcacggtcac
     2041 caccatcagc gggaccatga agtagaggta ggccagcacc agaccggtga agctgtagag
     2101 gctgaagccg gtccggtcca ggtggaggag ctgggtgacc gtgccggtcg taccgagcgt
     2161 cgcgatgaac gcgaaggcga gcggcgcacc ggagaagttg gccagcaccc cgctcgccga
     2221 gacgacgatc ccgcgcagcg ccgggcgcgg cgacgtgacg acggcctggg cgatcagggt
     2281 gccgatcacg gtcgccaaca gggcggtcac gagcgagagt tcgacgctgc cggtcagccc
     2341 ggtggcgtac gccccggaca gcgaaccgct gacgttctcc gtggagaggc ggctcgcacc
     2401 gctctccggg tccaggacgg tgaacgcccc gtacaccatg gtcccggcgg gcagcccgaa
     2461 gcacaccgcg aggaacgcga agaacgggac gacgacgggc caccggtgcc gccgcccgcc
     2521 acgacggcga ggggcggtgc cgccgtcccg gacgtccggg gcgggcggca cgggggcggc
     2581 cgcgcccgcc acgggcacgg agcccgtggc gggggcggga agtgcggtct ggtcgggcat
     2641 ggtcagctga ccgccttgcc ccagccctgg acgacggtct ccttggcctt cgcctcctgc
     2701 tccgcggtcg gctcctgcgg agtgccgtgg acctcgggga tccgggcgac ggctgccttg
     2761 tcggcgctgc cgtccttctt catcgcctcc aggagcgccg ggcgggagaa gcccttgagc
     2821 cagatgttct ggccctcggg gctgtagatg aactccagcc acagccgggc ggccgccggg
     2881 tgcggggcgt acttgttgac gccctggttg tagtagcgcg agtacaggcc gtcggcgggc
     2941 accacgacct gccagtcgac gcccttgggt tcgagcttct ggccgtaccc caggttgagg
     3001 tagtcccagt cgatcgagat cggcgtctcg ccctgctgga tggtggccag cgtggacttc
     3061 gcgggaacga agttgccctt cttcctcagc tcctggaaga agtcgagccc cggctgcgcg
     3121 tcgtccaggg acccgccgtt cgcgagcgag gccgcgatga ccgcggccag cgccgaactg
     3181 gactcggtcg ggtcgccgtt gagcgcgacc ttgttccggt actcgggctt cagcaggtcc
     3241 ttgaacgtct ccgggcagtt cttcacggcc ttggcgtcgc agccgatgga gatgtagccg
     3301 ccgtagttgt tcatgaagga ggcgtccggc tgcttctgcg cgtccgggat gtcgccccag
     3361 cccttgacct tgtacggcgc gagcaggccc ttcttcccgg cctcctgcat gtacgaggtc
     3421 cccaggtcca gcgcgtccac ggcccggtcc tggcccttgc gcttggccgc cgcgttcagc
     3481 gcgccctggc tgctgccgcc cgggtcctcg ttgttgacct cgacggcgta cttcttctcg
     3541 aacgccgcga tcatctcgcc gtagttggcc cagtccggcg cgagggcgta gacgttgagc
     3601 ttgccctcct tctccgccgc cgcgacgagc ttctccatac cgccgaggtc cgccgccgac
     3661 tccgccttcg ccgccttgct gttctgcccg ccggcgctgt cgggggcgga gccgcacccg
     3721 gtggccacca gggcggtgag gccgacgagg gccgcggcgg tcagaacgcg gcggggatgg
     3781 tgtgccttca cgatgcgtac tcctgggtct gcggcgagcc acctgtatgg acaagccatc
     3841 gtcagtaagc gagctgaagc tagcagcacg gcgatgggca ggtaaaggct tccggacgga
     3901 aaaagtgcag gtcagaagcg ttatcaagac gtaggtttac gttcctcgaa actggtaaga
     3961 cgcagggttc gcacttcggc gggaaacatt gactgcgcgc agattcaagg atgcggaaca
     4021 cccagcacgg atgacatgat cgccctggcc gtccacctcc cgtgacgccc cccgacgccc
     4081 cctaggagag acgtgacccg acggcaccag cagatagccg aggagctgcg cctcgccatc
     4141 gccgacggca cctaccccgt gggctccgag ctgccgtccg agtccgaact cgccctggcc
     4201 cacggcgttt cgcggggcac cctccggcag gccttcggca cgctccagtc ggagggactg
     4261 atcggctccc ggcagggcgc ccgccgcacg gtcctgtcca ccacccccag ccagagcttc
     4321 gccgaactgc gcagcttcgc ccagtgggcc agggcgggcg gccgcacccc cggcggcctg
     4381 gtcctcggct cccgccgcgc gaaggccacc gaggcggagg ccgcccagct ccacctcacc
     4441 cccggcgacg cggtcctgca cgtcctgcgg gtccgcaccc tggacggcga accggccctc
     4501 ctggaacgca cggtgtacgc cgggtgggtc gcggcggccg tcgaacgcct cccggacgac
     4561 tgcgagtcgg tcacccagag cctctacgac gaggcgggcg tggccatgag ccacggcgaa
     4621 caccacctgg acgcggtcgc cgcgggcacc acggacgccc gggagctggc cgtacgacgc
     4681 ggcgcgccgc tgctgcgggt gcgccgcacc acgaccaccc cggacggccg cccggtggag
     4741 acgtcggacg accgctacaa gccggactcg gtggtgttca ccgtacgcaa ctcggtccag
     4801 gccaacccgc tggtgcgcac ggcaccggac tgaggcccag gcccgccgca gccgccggac
     4861 accggccgcg cggccgcaca cctcgactcc cgactcccgc cccaggaaca gcgagcccgt
     4921 catgcccccg ctcccccagc acgctcagct cccccaagtc cccccgctcc cccgcccggc
     4981 ggccctgctg tgcgacatgg acggcaccct cgtcgacacc gagcacgcct ggctggacac
     5041 cgtcgccggc ttcctgcgga cgcagggctc cccggccgac gcgggcaccc tcgccccgtt
     5101 cgcgggcgcc gcactggccg acgcggcgga ccgcctcgta cgcgagggcc tcaccgcact
     5161 gtccccggca caggcactgg cccggctgga ccgggagttc acggcacggg tggcggcggg
     5221 ggtggccgtc cagccgggcg ccctccggct gctggaccgg gcacgcgccc tgggcgtacc
     5281 gacggccctg gtgaccgcgt ccgagcggca cgtggcggac ctggtgctgg acaccctggg
     5341 ccggcaccgc ttcgacacgt cggtcgcctc gggcgagacg gagcgcggga agccgcaccc
     5401 cgacccgtac cttgccgcgg cggccgcact cggtgtggca gcacccgact gcctggccgt
     5461 cgaggacacc cccaccggcg cggccgccgc cctggccgcg ggctgccgcc tgctcgcggt
     5521 cccgtcggta ccgggcatcg aaccgggccc acgcacggtc ctggtgacct cgctgacgga
     5581 ggcggacctg gcggacacgg cggtgtaggc cccgcactcc gcgcctcagc ccttcacgca
     5641 caccacctgc ttgagcttcg cgacgacctc gaccaggtcc cgctgctgct ccatgacctg
     5701 gtcgatcggc ttgtacgcgg ccgggatctc gtccacgaca ccggagtcct tacggcactc
     5761 cacgccctgc gtctgctcct ccaggtcctt ggtcgagaac cgcttcttcg ccgcgttccg
     5821 gctcatccgc cggcccgcgc cgtgcgacgc cgagttgaac gacttctcgt tgccgagacc
     5881 cttcacgatg tacgaaccgg tgcccatgga ccccgggatg atcccgtagt cgccggaccc
     5941 cgcccggatc gcgcccttgc gggtgaccag caggtccatg ccctcatacc gctcctccgc
     6001 cacgtagttg tggtgacagg agatgaccgg ctcgaaggtc acccgcgcct tcttgaactc
     6061 cttgcggacc acgtcctgga agagccccat catgatcgcc cggttgaact tcgcgtactc
     6121 ctgcgcccag aaaaggtcgt tgcggtacgc ggccatctgc ggggtgtccg cgacgaacac
     6181 ggccaggtca cggtcgatca gcccctggtt gtgcggcagc ttctgcgcct ggccgatgtg
     6241 gaagtcggcc agttccttgc cgatgttccg cgaaccggag tggagcatca gccagacaga
     6301 accggtctca tcgagacaga actcgatgaa gtgattcccg gatccgagcg ttcccatctg
     6361 cttcgtggca cgctcctgcc ggaacttgac cgcttccgcg atccccccga accgccccca
     6421 gaagtcgtcc caccccgccg tcgggaaccc gtgcagcctc cccgggtcca ccgcgtcgcc
     6481 gtgcatcccc cggccgaccg gaatcgcctg ctcgatcttg gagcgcagcc gtgacaggtc
     6541 gccggggaga tcgttcgcgg tgagggacgt cctgacggcg gacatcccgc agccgatgtc
     6601 caccccgacc gccgccgggc acaccgcgcc ctgcatcgcg atcaccgatc cgaccgtcgc
     6661 ccccttgccg aagtggacgt ccggcatgac ggccagaccc ttgatccacg gcagcgtcga
     6721 cacgttgcgc agctgctgca tcgcgacgtc ctcgaccgac gcggggtccg tccacatccg
     6781 gatgggaacc ttcgcccccg gtacctctac gtacgacata actcctcgat tcccccgaaa
     6841 agactgaaag cgcaaaaccg gtgccaagat cggcaaatcc gtcggccgac cggcattcac
     6901 agcagcgcgt gcgatacaca ttgtgtccat cggccgcctt cgagcggcaa ctcgttttcc
     6961 gtaccgaagg gagcctggga cggtgcgaca catggcgtac gtacccggcg tcgcgcttct
     7021 cgcagcgctc gccgtcggct gcagcgccgg cgccgacagc gacgcgaacg gcaccgacag
     7081 caaggcgggc accccggcgg tcacccccgc gccccccggc aagtacctca ccctgcccgc
     7141 cccctgccgg gccgtgccgc gctccacgct gaaggacctg ctccccggcg ccgcggaact
     7201 gcccggggac cagcaggaca aggtgttccg gggctcggcg gccgtcacgt acgacacgga
     7261 ccgcaaggtc gggtgcagct ggaaggccga cgggccgaac gccacgcgga gcctgtccat
     7321 cgacctcgaa cgcgtcgtct cgtacgaccc cgccgtcagc gacgacgacc gcgccgacac
     7381 cgtgtacgcg aagaaggaga aggccgccgg cctgtccgcc tcggcgcccc ccgggccgcc
     7441 cgacgagaag gacaagaagg gcgaggcgag cgaggggagc gggaaggcga aggatccggc
     7501 tgacgccgac gccacggatt ccgccgaccc ctcgccctcc ggaggcgacg acgcaaacag
     7561 cggtgaaagc accggcggga cccccggaag cagcagcagc ccggaggaag ccctcccctc
     7621 ccgcatcctc gacgacctcg gagatgccgc attcctccag gatctgccca aaaaggcagg
     7681 ttctaccgca cagcaccaca cggtgagcgt ggtgttccgc acatcgaacg tggtcgtgac
     7741 cgtccggtac gccgagcagc cggccctcgt cacccaggtg cccgacggca aggaacttca
     7801 ggagaaggcc caggcactgg cccggaagct ggccgacacg ctcagcgaat agccccctcc
     7861 gacaagcccc caccggccgg ctctccggtc ctcgggggcc ttcggcggcg gcgcggcacg
     7921 tcggccgccc gtcgtacggt ggctgtccgg aagacgtacc gacccgctac cgagcccgcc
     7981 cgtacaccgc acggaccgag acctccagca ccgagagctc cctgtgccat ccgagtgaag
     8041 gaaccatgca ccgatccgcc ccgcgcctgt cccgcatcct cgcctgcgcc gccgttccgg
     8101 tgatgctcgt agccgtcggc tgctcgtcgg actccggctc cgacggcaag aagaacgcgg
     8161 gctcctcgtc gtccggcacg gccggctcca agtccccgga gcccaccgtc gaaccggcga
     8221 agttcgccga tctgcccgac ccgtgcacct cgatcgggaa gaagacgatc gaggacctgg
     8281 tgcccgacgc caagaagaag ggcggcacgg cgggcgggtc caccgacctg tcggtccgca
     8341 gcagctgctc ctggaacggc ctggacgacc agggcgtcaa gggctcgcag taccgctgga
     8401 tggacgtcgg cttcacccgg ttcgactcgg accagtcgct gggcagcggc gccaagcgcg
     8461 ccaccgcgga ctacacgaag caggtcacca aggcgaaggg gtccgagggc gccgagaagg
     8521 tcgccgcgga gcccgcggcc ggcatcggcg acgaggcgac cctggtcacg tacggcctca
     8581 gcaagacgga cgaggacttc gtgtacgcca ccgtcgtggc gcgtacgggc aacgtcgtcg
     8641 tcaccctgac gtacaacggc gcgggctacg ccggggcgaa gaccccgtcc tcctcggaca
     8701 tcgtgaaggg cgcgcagaag gcggccgggg aagcggtcgc cgcggtcggg aagaccgccg
     8761 gctccggggg cgccgacgag gactcgggca agggctcgga caagggcgag tcctccgcga
     8821 agccgaagtc gagctgaccc cggcaccccc agcacggctt tcccgcgacc cggccctccc
     8881 cgagggccgg gtttcgcacg ttcgggcaaa ccccggtggc atacgcctgt caccttcatg
     8941 ccaaccctcc cccggttccg tttcgagcgg gccggacgcc gttacgctcc acggcgaacc
     9001 ccgaggaaag gcaagggaat tgcgcaatcg aatcgcattc gccgcagcgc tcacgaccgg
     9061 tctggtcgcg ctcaccgcca ccgccgccac cgcggctccg gccaagcccg ggacggcggc
     9121 atccggcgat acccgtgcgt gcggggacgt gaagctgtcc ggcgccctgc ccgtaccgcc
     9181 cgaaggcatg gccgtacggc aggacgtctc catcggcccc gactgcgagc cggtgctcgg
     9241 ccccgcacgg ctggtggcga aggccggccc ggcggcgacc gcacggacgg cccgggccgc
     9301 cgcccagggc gaccggcagg tccgcagctg gtccgagatg tacgactgct gcaacatccg
     9361 gatgacgggg ctctacacga cgtccgactg gagctccgac ggcacggtgg tcaccgcctc
     9421 gtccaccgaa gcgacccagc agtggaaccg tgaaccatgg aacgcgggct ggtcgctgaa
     9481 gtcctcgggc acatccgccg actgcgtcgc gaactgcgcg gtctccacca acgtggccga
     9541 cgcctcgttc acctacaagg gaatcttcga cctgacgggc aacgtgtacg ccaacacgca
     9601 ccgctccacc gtggccctca aggccgacgg gaccgcgtcc tgcgagttcg aggtcgacct
     9661 gaagaacacg ttcatcggct ggaactggca gcgcggctgc gagtgacaga aacaaaagcc
     9721 ttcactaccc cgggagaaat gaccggggac gcacattccg ctgtggcact cacctgccac
     9781 tcctcttgat cggcgcatgg cgggtcagca cgataagcct cgccatgctc catccgtaga
     9841 gagaaaagga gtgtcatcca tgaagaaggc tgtctacgag acccctgagt tcaatgccgc
     9901 gggctccttc cgcagcgaga ccggcctggt cgtcgtcgtc caggccgact ggaacgcccc
     9961 cggctggttc tagtacctcg ttcctcagga gttgactgtg atggatcacg gcacgccgca
    10021 tttcctggcc tttcccgatc gggacgatgc ggcggccgtg gtccgtcgcc tgcgttccgc
    10081 gcatcccggt ctcaagtcgg tcgaccaccc ttcgggccgc ccctggatcc tgggcagctg
    10141 ggacgacgag gacctggccg tcgcccgggc cgggcacgat tccgtggcgc tgatcggcac
    10201 ccttccccgg ctcgggggcg cgctccagga cctggccgcc cgcatgaacg gctccgccgc
    10261 cgcgctcgac accctgccgt cggtgctgcc cggcgacttc cacgtactcg gcagcgtcgc
    10321 cggcgctctg cacgtccagg gcaccgccta cggcacccgg cgcgtctacc acggccgtgt
    10381 cgacggcacg gtggtcgcct cggaccgggc gctgcgcctg gccgaactcg tcggggcctc
    10441 catcgatatg tcggcgctgg cctggaagct gctgctgccg gtgccgcgac acctggacgg
    10501 ccgcaccatg tggctcggca tcgacgccgt ggagcccggt ctgcgtctgg tggtcggcgc
    10561 gggcgacgag cgggtccgca ccgtacgccg gcaccggccg cccgagtccc ggctgcggat
    10621 ggccgaggga gccgcggccg tacgggaggc cctggtctcc tcggtgcggg cacgcaccca
    10681 ccgcggcggg ctgatgagct ccgacctctc cggcggcctc gattccacct cgctcagctc
    10741 gatcgccgcg ggccagctcg gcgagggaga attcatcgtc tgcaccaacg gcggtgacga
    10801 atcgatcaac gaggacggcc actgggcgcg ggtcgcggca tccgcctggc cgcacgtgga
    10861 gcattaccag ctccctcccg aggaacagcc gctcttctat tcgggcgcac tcgacaccgc
    10921 ctgccagtcc gatttccccg gaatgatcgc agtcagccgg aaacgcgcga cgatccttat
    10981 gtctcgcatg gcggaacggg gctcccggct gcatatgggc ggccagggcg gtgaccatct
    11041 gttcttcagt tccggatcgc actattacag cctgctgacc cgtcgccccg ttctctctct
    11101 tcagcgtatt cgcgcatatg gaattcttta tggatggtcc tggaccaccg tgctgcgcca
    11161 gctgtccaac cggggttcgt accgcagctc gctggccgcc atcgacctgg acgggtcggg
    11221 cgacctcggc ttcagcgccc ccgggctgaa ctgggtacgc cagcccgtgg tgccgtcctg
    11281 gctcacggcc gactgccggg agctgctggc gaaggagctc gcccgggtgg tcgcggaggc
    11341 ggagccccgc agtccggtcg tcagccggca tctggagctg gacaacctgc tcaccaccac
    11401 gctggacatg gcgtccacct gtgacgcctc ccggctcgcc ggagtgccgt tgtccatgcc
    11461 gtacttcgac gaggccgtgg tggacgccgc gctctccgtg cgcgtcgagg accgggcgac
    11521 cccctacgcg tacaaaccgc tgctgatgga ggcgatgcgc gggatccttc cggacgcgtg
    11581 ccgggcccgc acctccaagg ccgagggcag cttcgacgcg gtcggcggcc tctaccggca
    11641 ccgcgcggaa ctcatcgagc tctggcagga gagcgcgctg ggcaaggcgg ggctgatcga
    11701 cgccgcccgt ctcgcggatc tgtgcagccg gccgggcacc ccggacctga aggacggatc
    11761 catcaactcc acgctcagct gcgaggtctg gctgcgttcc gtcgcctgac gagcggcaac
    11821 acgacgaagc aacgacggca cccaccccac agacaaggat gagccaggca tgaaactgcg
    11881 taaccgcaag catctggtcg tcaccgacac cgactacggc gccgtgctgc tggacaccaa
    11941 gagcgggcag tactggcagc tcaacccgcc cggcgcggtg atcgtccgga cgttgctgga
    12001 cggcgagggt cccgacgagg cgatacggcg ggtcaccgat cgcttcgacg tggagaccga
    12061 gcgggccacc accgatgtgc acgcgctgat cgaagccatg cgctcggccg gggtggtgga
    12121 gaagtgagcg tcaccgtcgc gctcaaccgc gaccaccggc cgcgctcctg gaagctccgc
    12181 ctccagacca ggctcgccat ctgcctcgcc cggatcctgg cgctcttcaa gccgtacgtg
    12241 gtgcgccgcg tgctggtccg gctgagcaag ggggcgaagg ccgccgacgc cgccgagatc
    12301 acgaccgcgc gggactccgt actcgcctcc agcctcgggc tgcacgggct gcgcgcctgt
    12361 ctgccccgtt ctctggcgac ggcgctgctg tgccggttcc ggggggcctg gccgacctgg
    12421 tgcgtggggg tgcgcacggc accgccgttc gccgcccacg cctgggtcga ggccgggcgg
    12481 gagatgatcg gcgagacggg cggctacgac agctactcgc ggctgttcac cgtgccgccg
    12541 accacgccgc ttcccctcgc ggagaacgaa ccggccacgg aggacgagcc ggccccggac
    12601 cagtaggccc ggcccaccgg aagcccggcc gtcagaaggc ccgtccccgg gggccgggac
    12661 cgtcggcggc cgggctgaac cccgggcgga aatcccgtca gaaaccccgg caagtcgccg
    12721 ccatggcgat cgcccggagc ctcccgcgct cctccccgcg taacgaaact cgtacacatg
    12781 tgccaggctg tgccatcgcc gggcgtctgc agcctggccg aagaacagag ccgggcgcac
    12841 acgtcgggtt cgggtaacag aggtcgggga ggggatcgct ggtggccgcg atgcagctga
    12901 cacgcacgca ccgcatactc atcggggtcg tcgtcgcggg tgcggtggtc atcgccgcga
    12961 tcgggttcgc gggctcctac gccgccgtgc gcgagctcgc ggaggagaag ggcttcggga
    13021 cgttctccct ggtcttcccg atcggcatcg acgcgggcat ctgcgtcctg ctcgccctgg
    13081 acctcctgct gacctggatg cggatcccgt tcccgatgct gcgccagacg gcgtggctgc
    13141 tgacggcggc gacgatcgcg ttcaacggcg ccgcctcctg gcccgatccg ctgggcaccg
    13201 cgatgcacgc ggtgatcccg gtgctgttcg tcgtctccgt cgaggccgcc cggcacgcgg
    13261 tgggccggat cgcggacatc acggccgaca agcacatgga gggcgtccgc ctcacccgct
    13321 ggctgctctc gccgatcccc acgttcaagc tgtggcggcg gatgaagctg tgggagctgc
    13381 gcagctacga gcaggtcatc aagctcgaac aggaccggct gatctaccag gcccgcctcc
    13441 aggcccgctt cggccgcaac tggcggcgca aggctccggt cgagtcgatg atgccgctgc
    13501 gcctggcgaa gtacggtgtc ccgctcgccg agaccgcccc ggccggcctg gccgccgccg
    13561 gcatcgaacc ggccctgctg cctccggtgc ccgtcgaggc cgaccgtccg aaggccgagc
    13621 tgagccccgc cggtccggac cgggccgccg agccggtcca cgccgagctg ccgtacggac
    13681 cgcagcccag cgccgagcac gggcagcaga aagcccggcc ggagcacgcc catccccacc
    13741 cccagcagca acagccccaa cctcaccagc aacaacagcc cctgtcgctc cagaagcagg
    13801 acccgcccgt cccgcccacc cacgacagcc cctggttcgc cgcccagaag ctgccggaca
    13861 acggccacga gagcgcgtac gacccgcagt acgtcgaggg cccggagccc ggcccggtcc
    13921 agatccccgc gggccccggc cgcacccggc cgctcggtga cgtcggcacg atcggcgcgg
    13981 tcccgcaccc ccgccaggag gagcaggccc ccgagccgcc cgaggtcccc gaccccgagg
    14041 aggccccgca ggtggagcag tggcccatgg aggacaccga cttcgcccgg gaggcgtacg
    14101 aggtgttcag cgagtacacg gacgcgcagg ggcagtaccc gtccgtggag gtcctggaca
    14161 tccacctcgc cgacacgcgc aacgtccgtc acccgcgctc gacggagctg ctccagcagc
    14221 tgatgtcgca gttcagggag gcctacgcgc agcggccgac cgccgagcag cctgcctgac
    14281 ccggccccgt acacacgacg aaagggccgc cgcccgggaa ggattcccgg gcggcggccc
    14341 ttcgccgttg tcagggtgtt acgcgcccag cagcctgcgc acccggtccg cccccaccgc
    14401 gagcagcagc gtgggcaggc gcgggcccgt gtcgcggctg acgaggaggc ggtagagcag
    14461 cgcgaagaag gaccgctgcg cggccttcag ctcgggcgtc ggcttggcgt ccggctccag
    14521 gcccgccagc accttcggca cgccgtagac gagcgtggtg agcccgtcca gcgaccagtg
    14581 ggtgtccagg ccctccagga ggaggcgcag ggactcgcgg ccccggtcgt cgagcgagcc
    14641 gaggagctcc ttgtcgggct cgtcccggac gatggtgcgg gcctcggccg ggacctgggt
    14701 ggtgatccag ttctcggcgc ggtcgaggcg cgggcgcgcc tcgtccagcg aggtcagcgg
    14761 gttctccggg tccagctcgc tgaggatgcg cagcgtctgg tcctcggcgc cggcggtgat
    14821 gtcggcgacc gaggcgagcg tccggtacgg cagggggcgc ggggtgctcg gaagctcccc
    14881 ggcggccgtg cggacagccc gggagtacgc ggcggcgtcg gcgggcagca cggtgccgtc
    14941 ggcgaccttg cggcccagcg agtcccactc gtcgtacagc cgctggatct cctggtcgaa
    15001 ggcgatcttg aacgactggt tgggcttgcg gcgggcgtag agccagcgca gcagcggcgc
    15061 ctccatgatc ttcagcgcgt cggccggggt gggcaccccg cccttgctgc tggacatctt
    15121 ggccatgccg gagatgccga cgaaggcgta catgggcccg atgggctgca cgccgtcgaa
    15181 gacctcgcgg acgatctgcc cgccgacgac gaaggaggag ccgggcgagg agtggtcgac
    15241 gccgctgggc tcgaagatca cgccctcgta ggcccagcgc atcggccagt cgaccttcca
    15301 gaccagcttg ccgcggttga actcgccgag gcggaccgtc tcggcgaagc cgcaggccga
    15361 gcaggtgtag ttcagctcgg tggtgtcgtc gtcgtaggag gtgacgacgg tgaggtcctt
    15421 ctcgcagttg ccgcagtagg gcttgtacgg gaagtagccg gcgctgttgc cgctgccgtc
    15481 gtcctcgtcg gcggcgccgg agccctcggc ggcctccagc tcggcctcgt cgaccttctt
    15541 ctgctgctgc ggcttcttgc cgcccttgcc ctgggccgcg gccgggtcct tcttggtccg
    15601 gtagcggtcg aggacggcgt cgatgtcggc gcggtgcttc atcgcgtgca ggatctgctc
    15661 gcggtaggtc ccggcggtgt actgctccgt ctggctgatt ccgtcgtact cgacgcccag
    15721 ctcgtccagg gccgccgtca tggcggcctt gaagtgctcg gcccagttcg ggtacgccga
    15781 gccggccggg gcgggcaccg aggtcagcgg cttgccgatg tgctcggccc aggacgcgtc
    15841 gacgcccggg acgccgttcg ggaccttgcg gtagcggtcg tagtcgtccc aggagatcag
    15901 gtggcgcacg gtgtacccgc ggcggcggat ctcgtcggcg accaggtgcg gggtcatgac
    15961 ctcgcggagg ttgccgaggt ggatcgggcc cgacggggac agaccggagg cgacgacgac
    16021 cggtttgcca ggcgcacgac gctccgattc ggcgatgaca tcgtccgcga agcgggagac
    16081 ccagtcggtc tcggtgctgg tctgactctc ggccacggtc ggcacgtcct tctctcgttc
    16141 tgtcggtccc agtgggttac cgaccattct cccagctacc ccccgcagcg cgaaaacggc
    16201 tttacgcccc gtgggatact ggaccgatcc cttgtacccc tacggaaacg gcagccagac
    16261 atggcctcgg tcccttccct cgcttccacg ctccagcagc agctggcgga cgccctgacg
    16321 gcagccctgc cggatgccgg caccgcggac ccgctgctgc gccgaagcga ccgggccgac
    16381 ttccaggcca acggcatcct ggcgctcgcc aagaagctca agggcaaccc ccgggagctg
    16441 gccggccagg tcaccgccgc ccttccggcc ggcgagctga tcaaggacat cgaggtctca
    16501 ggacccggct tcctcaacat caccctcgcg gaccgggcga tcgtcgagac gctggccgcc
    16561 cgggccgccg acaccgaggg ccgcctcggc gtgccggtgg ccgcggacgc cgggaagacg
    16621 gtcatcgact acgcccagcc caacgtggcc aaggagatgc acgtcggcca cctgcggtcg
    16681 gcggtcatcg gcgacgctat ggtccggatc ctggagttca ccggcgagga cgtcgtccgg
    16741 cggcaccaca tcggcgactg gggcacccag ttcggcatgc tcatccagta tctgatcgag
    16801 cacccgggcg ccctgaagca cgagggcggc gcgagcgacg gcgaggcggc gatgtcgacg
    16861 ctgaaccggg tctacaaggc gtcccgggcc ctgttcgact cggacgagga gttcaaggcc
    16921 cggtcccggg accgggtggt ggcgctccag gccggtgacg cggagacgct ggagctgtgg
    16981 cagggcttcg tcgacgagtc gaagatctac ttccactcgg tcttcgacaa gctcgacatg
    17041 gaggtccgcg accccgacat cgtcggcgag tccggctaca acgacatgct ggaggagacc
    17101 tgccggatcc tggaggagac gggtgtcgcc gtccgctccg agggtgcgct gtgcgtgttc
    17161 ttcgacgatg tgaagggccc ggacggcaac aaggtcccgc tcatcgtgaa gaagacgaac
    17221 ggcggttacg gctacgcggc gacggacctc tccgcgatcc ggaaccgggt ccaggacctg
    17281 aaggccgaca ccctgctgta cgtggtggac gcccggcagt cgctgcactt caagatggtc
    17341 ttcgagacgg cccggcgggc cggctggctg ggcgacggcg tcaaggccgt gcagctcgcc
    17401 ttcggcacgg tcctcggcaa ggacggcaag ccgttcaaga cccgcgaggg tacgacggtc
    17461 cggctggagg acctcctcga cgaggcggtc gcccgggcca ccgcggtcgt ccgggagaag
    17521 gccgggaagg tgggcctgtc cgaggaggag atcgtcggga acggccggta cgtcggcatc
    17581 ggcgccgtga agtacgcgga cctgtcgacc tccgccgtgc gggactacaa gttcgacctg
    17641 gaccagatgg tgtcgctgaa cggcgacacg tcggtctacc tccagtacgc gtacgcacgt
    17701 atccagtcga tcctgcgcaa ggccggggac gcggttccgg ccgcccaccc ggagctggcg
    17761 ctggccccgg cggagcgggc gctcggcctg cacctggacc agttcggcga ggtgctggcc
    17821 gaggtggccg cgggctacga gccgcacaag ctggccgcgt atctgtacca gctggcgtcg
    17881 cacctgacga cgttctacga ccagtgccag gtgctcagcc cggacaacgc cccggaggtc
    17941 gtcgagaacc ggctcttcct ggtcgagctg accgcccgga ccctgcacca ggggatggcg
    18001 ctgctgggca tccggacgcc cgagcggctc tgaccgcgtc cgccgtacgt acgtgatcgg
    18061 ccccggcacc tgttccgcag gtgccggggc cgacgtgcgt gcagggaggc cctacggggc
    18121 ggtgagctcc acgacgacgt cgtagaccgc cgggttcggg gtgaccggct gcttcgtctc
    18181 ctcgcgcgcg gcgcgggtcc gggaggcgaa gtcggggtcg gcggtcgcgg cctcccacgc
    18241 ctcctggctc tcccagtggg agacgttgac gagctggaag cgggagtccg aggagcgggc
    18301 ccggtgcatc cgggagtcga tgaagccggg cttgtcccgc atgaggcggg cccgctgttc
    18361 ccacttcccg acgaacgcgt cgagttcgtc ggcggctatc tcgaagacgt tgatgaaggt
    18421 gacggacgag tcgggggcta aggcgctctc tgtggtcatg ccgcaactct aggagccggc
    18481 cgcgtggcta ctgagggcgg cccaacgccc atcccgacac gtcggagagg cgtccgcgcc
    18541 acagcggcag ggagaccggc gccgcggccc cggagacgag ggtgacgtcc cgcagatgga
    18601 tccagcgggg cagccgggcc gcccccgtct cgtcctcctc cgcacgcagt tcccgtacgc
    18661 cctggtcgac ggtctcgggg aactcggcga gcaggttggc cccctcgccc tcgacctgcc
    18721 gcaggctcct ggcccactcg gccttccact gctcgtgccc gatgacgtca ccgtgcagga
    18781 tgccgccggg gtgcgtgagg gtgaggggca ggctggagcg cggttcctcg tccaggagct
    18841 ggatgagcaa ctggagctgg aggtcgggca gaggttcggt gatcaccgcg gcggacggtg
    18901 ccggcgaggt ctcggcggtg gcgctcatgg gcctgccctt cacatggcga tggcggacga
    18961 cggtcgtcct ccccgcctgc ccggccaggg cgcgcgcacg ccccgtgggc cgggtcgtcg
    19021 ggatcagagg aaccggcgga tgggcatgac ggccgcttcc ttggcccgct ggaggaggtc
    19081 gcggcgcttc caccggccgc gctcgatcag cacgctcttg gcgcggtcat cctcgaagtg
    19141 gccgtcgagg gtggcggtga agtcctggtc gaggacggcg agcatgacct cctcgtcgtg
    19201 gtcgagggag cgccggttga agttcgtgga gccgatgagc gaggcgaccc ggtcgacggt
    19261 gagggtcttg gtgtgcatca tcgtcggctg gtactggtgg atcttcacac cgcaggcggt
    19321 caggtcctcg tagtagcgct gcccggcgag ctggcagacc cgcttgtcgg tgtgcggccc
    19381 cggcagcagg atctcgacct ccaccccgcg cgcggcggcg tcgcacagca gcccggtgaa
    19441 gtaggcgtcg ggggcgaagt aggcggtggt gaggcggatg cgttcctcgg cggactccag
    19501 gacgacccgg atcagggtct gcatgtcctg ccagccgaag gaggccgagc cgcggacgac
    19561 ctggacgacc gagtcgccgt ggtgctcctc gctgatgaac cggtcgcgct cgtcgaacag
    19621 ctcgtcgtgg cactcggccc agttctgggc gaacgcggcg gccagtccgt cgacggcggg
    19681 cccggtgagc tggacgtggg tgtcgcgcca ctcgtgctcg ttgcgggcgt cgccgcacca
    19741 ctcctcggct atcccgacgc caccggtgaa cgcggtctgc tcgtcgacga cgaggacctt
    19801 gcggtggcag cggtggttct gcttgagcgg tgagaggtag aggggcttgc ggaaccaggt
    19861 gacggtgacc ccggcctcgt ccatcatggc cagctggtcc ttctcgatga gccgcgatcc
    19921 gaacccgtcg agcatgagcc gcacccggac cccggcgcgg gcgcggtcgg ccagggcctc
    19981 ggcgaactgg agggcgatgt caccccgcca gtagacgaag gtcatcagat cgacggtgtg
    20041 ctccgcctca cggatcgcct tcagcatcgc gccgaagatg gcgtcgccgt tacggagcgg
    20101 gacgagggag ttcccctcgg tcgcggcgat accgatcagc cgctccagtc tgcgtctgag
    20161 tcgctcggac cgttcctcgc aggtgcggtc ctccggggcc gtgcggtcgg aggcatcggc
    20221 tgcagtggcg gacatgaatc acctgtggtc tcgcgggcgg ggcggccgca cgccgccgtc
    20281 gcgcggcggt gaggctgcca gaacctcgca gactgtactc ccgagttccg gacatgtgta
    20341 cgaccaccta tcggtcagcc accgcgatga accgatacgc gacctttgac cgacatgaaa
    20401 ttgaatgccc ggaatcagcg ccgctcctcc cgtcctccgc ccaccgcacc ttccccgccc
    20461 accgcacctt ccccgcccac cgcaccttcc ccgcccaccg cgccttcccc gcccaccgcg
    20521 ccttctccgt ccccctcgtc cagccggagc gccttgagcc ggcggctcgc ggggcggcgg
    20581 ccgcccctgc ccccggcggc ggcccggccg atgacggagg gcaccacgtt ccccggcacc
    20641 cgcagggcgt ccagcacctc ggccagatgg cggctcagct cggccgacgc ggcggccccg
    20701 tcccggtccg ccacggcgtc gcggacgatc cggtgggagg cccagccctc gggctcgacc
    20761 gtcatcacga cggagacgaa ggccagcatg gtccggtact ggagcggctc cagcacctcg
    20821 atcagcgtcg cgtggcccga catcagggtc agggtccgca ggaactcccg gtgcgcccgg
    20881 ttggcctccg gccgggcccg ccgatccagc gcgtcgaagc cctgctccag cgcccggtcc
    20941 agcgccgcca gttggtccgc gtcatgccgt tcggcggcca gctcggcggc ccagggctcc
    21001 agtcgggccc gcgcctccac ggtctcgacg atccggtcga ggtcctccgg cccgagccgg
    21061 ggaatgaagg ccccccggtg cgcgtgcagt tcgacgagcc cccggccggc caggctgcgc
    21121 agcgcctcgc gcacgggcag ccgggacacc ccgagcgcct ccgccaccgc ctcggtgacg
    21181 atgtgctcgc cgggccccag gcgcagcccg aggatctccg cgttgagcag gtcgaagacg
    21241 cgcttctcga cggtggcggt cgcggcggga cgacggggcg gcggcatggc ccccagtatc
    21301 cggtacgggc gtggatcgcc gtcgggcacg ggcgcggatc gccgctggtc ctctcggcct
    21361 cttgaccggc cgacgtgaat cggatccaat ttaactatgg ctacccttac taacatcgag
    21421 cctgttgccg ccgcccgcgc actcgcaccc cgcctgaggg agcacgcggc cgaggccgac
    21481 cggctgcgca ccctgcccga cgccaccgtc cggctgctgg acgaagcacg cctcttcgac
    21541 gtcctgaccc cccgggagct gggcggcacc gggctcggct tcgacacggc ggtcctggtc
    21601 gccgaggagt tgtcgagggg gtgcgcgtcc gccggctggg tgtgcgcggt gctgggcggc
    21661 accgcctggg ccgtggcgca gatggacccc cgggcccgcg aggaggtctt cgccgggccc
    21721 tccacccgga tcgccctgca actgcggctc ggtggcccgc ccgccgaacg cgtcgcggac
    21781 ggctacctgc tgcacggcat gcgcggccgc ttctgctcgg gcatcgacca tgccgactgg
    21841 atcctcgccg gggtgagcgc gccgcgcacg gcgggagccg acccggaacc gcacttcgcg
    21901 ctcctccccc gggagcggac cgagggcgtc gacgactggc acaccagcgg cctgcgcggc
    21961 acgggcagcc gctccttcac cacgcccgcc gcacccggac tcctcgtccc cgaacaccga
    22021 gtcctgcccc tgagcgccct cgacccgctc aacacctccc cgtacggccg cccggggacc
    22081 gccccgtacc gcatggcgca caccgccgtc ggcacggtgg ccctcgcggg cgtcctcctc
    22141 ggcacggcac gggccgccct ggacgcccac acggagtccg ccggccgcgc cccgggcccc
    22201 gacgcgctgg acgtacccgc gctcaccgcc acggttgacg cggcccgcgc cctgctcctc
    22261 gccgacctga aggcgctcgc cgactccgcg acgccgggcg ggagccggga ggaacgggcc
    22321 cggatgcgcc gggacatcgc gcacgccggg acgcgctgcc gcgcggtcgt caacgcggtg
    22381 tacgaggcct cgggttcggg cgtgatctac gacgacgcgc ccctccaacg gatctggcgc
    22441 gacgccaacg cggccgccca gcaccccacg ttcgacctcc gccgctgggg cccgccgcac
    22501 ctggaagcgc agacggaggt caggtccgcc gacatcacct caccccagga gacctccgca
    22561 tgaacaccaa accgaccacg cgcccctccg acctgctgcg ccgcac
//
