LOCUS       NZ_KZ819178            10399 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. CS131 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ819178
VERSION     NZ_KZ819178.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS131
  ORGANISM  Streptomyces sp. CS131
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7968990)
  AUTHORS   Malmierca,M., Ceniceros,A., Mendez,C., Salas,J.A. and Olano,C.
  TITLE     Genome analysis of twelve Streptomyces spp. associated with Peruvian
            leafcutter ants
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7968990)
  AUTHORS   Malmierca,M., Ceniceros,A., Mendez,C., Salas,J.A. and Olano,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2018) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 88.88x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003116755.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 09:38:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,994
            CDSs (total)                      :: 6,912
            Genes (coding)                    :: 6,769
            CDSs (with protein)               :: 6,769
            Genes (RNA)                       :: 82
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 41 of 143
            Pseudo Genes (incomplete)         :: 122 of 143
            Pseudo Genes (internal stop)      :: 12 of 143
            Pseudo Genes (multiple problems)  :: 31 of 143
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:40:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1524065
            Orig. end                         :: 1534464
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ819178.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Professor JA Salas
            laboratory.
FEATURES             Location/Qualifiers
     region          1..10399
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="10"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..10399
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10399
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5399](+)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5399
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     misc_feature    94..103
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.02"
                     /tool="antismash"
     misc_feature    complement(160..175)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.76"
                     /tool="antismash"
     gene            complement(314..1390)
                     /locus_tag="DBP20_RS06825"
                     /old_locus_tag="DBP20_06825"
     CDS             complement(314..1390)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512211.1"
                     /locus_tag="DBP20_RS06825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_06825"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_032778402.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 2.3e-17, bitscore:
                     61.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRVKGRVLVGPDEVRDELWAVDGRITYERPPGADDAVTVRGWAL
                     PGLVDAHCHVGLDRHGPVDAATAEKQALTDREAGTLLIRDAGSPSDTRWIDDREDLPKI
                     IRAGRHIARTRRYIRNYAHEIEPGDLVAYVAQEARRGDGWVKLVGDWIDRDAGDLTACW
                     PRGEVEAAIAEAHRLGARVTAHCFAEESLRDLVEAGIDCIEHATGLTEDTIPLFAERGV
                     AIVPTLVNIATFPDLAAGGEAKFPRWSAHMRQLYDRRYDTVRSAYDAGIPVYVGTDAGG
                     SLAHGLVAGEVAELVKAGIPPLEALSATAWGARRWLGRPGLEEGAPADLVVYDADPRAD
                     VRVLAAPRHIVLNGRVIG"
     gene            1551..2657
                     /locus_tag="DBP20_RS06830"
                     /old_locus_tag="DBP20_06830"
     CDS             1551..2657
                     /NRPS_PKS="Domain: Aminotran_5 (18-283). E-value: 9.1e-27.
                     Score: 85.8. Matches aSDomain:
                     nrpspksdomains_DBP20_RS06830_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123620.1"
                     /locus_tag="DBP20_RS06830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_06830"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_109178105.1"
                     /sec_met_domain="Aminotran_5 (E-value: 2.6e-20, bitscore:
                     71.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPFLDLPPLTAGHFAAIERRVARLLATEQDVVITQGEALLPLE
                     GCIRSGARPGSTALNVVTGPYGQTFGNWLRDCGAQVIDLAVPFHTAVTAGQVAEALAEH
                     PEIDFVSLVHAEAATGNTNPVAEIGEVVRAHGALFMLDAVASVGAEPLLPDAWGVDLCV
                     IGAQKAMGGPAGVSAVSVSARAWERIAANPAAPRRSYLSLLDWKERWIDGGRTALPHAP
                     AQLEMLGLEACVARIEDEGLETVMARHASAAAATRAGAVALGGGLEPYVHEARDAAPVA
                     TTLRAPAGTDAAALVAAALAADPALPLVAGGGALSKEMIRVNHYGADATRGAVLSSLAA
                     LGAALTDAGRQVDIEAARRAVSKTWPSR"
     aSDomain        1605..2399
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DBP20_RS06830_Aminotran_5.1"
                     /evalue="9.10E-27"
                     /label="DBP20_RS06830_Aminotran_5.1"
                     /locus_tag="DBP20_RS06830"
                     /protein_end="283"
                     /protein_start="18"
                     /score="85.8"
                     /tool="antismash"
                     /translation="IERRVARLLATEQDVVITQGEALLPLEGCIRSGARPGSTALNVVT
                     GPYGQTFGNWLRDCGAQVIDLAVPFHTAVTAGQVAEALAEHPEIDFVSLVHAEAATGNT
                     NPVAEIGEVVRAHGALFMLDAVASVGAEPLLPDAWGVDLCVIGAQKAMGGPAGVSAVSV
                     SARAWERIAANPAAPRRSYLSLLDWKERWIDGGRTALPHAPAQLEMLGLEACVARIEDE
                     GLETVMARHASAAAATRAGAVALGGGLEPYVHEARDAAPVATT"
     misc_feature    2677..2690
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.98"
                     /tool="antismash"
     misc_feature    2678..2691
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.13"
                     /tool="antismash"
     misc_feature    complement(2679..2692)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.35"
                     /tool="antismash"
     misc_feature    complement(2680..2693)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.7"
                     /tool="antismash"
     misc_feature    2783..2800
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.75"
                     /tool="antismash"
     misc_feature    complement(2785..2800)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.62"
                     /tool="antismash"
     misc_feature    2795..2810
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    2929..2941
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.5"
                     /tool="antismash"
     misc_feature    complement(2941..2955)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.51"
                     /tool="antismash"
     misc_feature    2951..2965
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.36"
                     /tool="antismash"
     gene            2965..3495
                     /gene="ectA"
                     /locus_tag="DBP20_RS06835"
                     /old_locus_tag="DBP20_06835"
     CDS             2965..3495
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123622.1"
                     /locus_tag="DBP20_RS06835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_06835"
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_109178106.1"
                     /transl_table=11
                     /translation="MTAAPADLARARSEFLSIDAPRVEDGAAIWRIARDSQVLDLNSSY
                     SYLLWCRDFAATSVVARGESGEPIAFVTGYIRPDRPQTLVVWQVAVDAAHRGKGLAATL
                     LDALTARVAADQGLSSVETTITPDNTASDRLFTSYAERHDVALEQEVLFDGDLFPEGTH
                     LPEVLYRIGPFAT"
     gene            3649..4911
                     /gene="ectB"
                     /locus_tag="DBP20_RS06840"
                     /old_locus_tag="DBP20_06840"
     CDS             3649..4911
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0045303 - diaminobutyrate-2-oxoglutarate
                     transaminase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (28-363). E-value: 3e-71.
                     Score: 232.1. Matches aSDomain:
                     nrpspksdomains_DBP20_RS06840_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156968.1"
                     /locus_tag="DBP20_RS06840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_06840"
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_032761400.1"
                     /sec_met_domain="Aminotran_3 (E-value: 6.4e-76, bitscore:
                     254.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITPPELSVFETLESEVRSYCRGWPAVFDRAQGARLTDEDGHSY
                     LDFFAGAGSLNYGHNNPVLKRALIDYIERDGITHGLDMATTAKRAFLETFQNVILRPRD
                     LPYKVMFPGPTGTNAVESALKLARKVKGRESVVSFTNAFHGMSLGSLAVTGNAFKRAGA
                     GIPLVHGTPMPFDNYFDGTVPDFLWFERLLEDQGSGLNKPAAVIVETVQGEGGINVARA
                     EWLRALKELCERQDMLLIVDDIQMGCGRTGGFFSFEEAGIVPDIVTLSKSISGYGLPMS
                     LCLFKPELDIWEPGEHNGTFRGNNPAFVTAAAALQAYWADGQMEKQTLARGEQIEQTLL
                     AVCAEEPTASFRGRGLVWGMEFEDPARASAVCARAFELGLLLETSGPQSEVVKLLPPLT
                     ITPEELDEGLRTLARSVRETA"
     aSDomain        3733..4737
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DBP20_RS06840_Aminotran_3.1"
                     /evalue="3.00E-71"
                     /label="DBP20_RS06840_Aminotran_3.1"
                     /locus_tag="DBP20_RS06840"
                     /protein_end="363"
                     /protein_start="28"
                     /score="232.1"
                     /tool="antismash"
                     /translation="FDRAQGARLTDEDGHSYLDFFAGAGSLNYGHNNPVLKRALIDYIE
                     RDGITHGLDMATTAKRAFLETFQNVILRPRDLPYKVMFPGPTGTNAVESALKLARKVKG
                     RESVVSFTNAFHGMSLGSLAVTGNAFKRAGAGIPLVHGTPMPFDNYFDGTVPDFLWFER
                     LLEDQGSGLNKPAAVIVETVQGEGGINVARAEWLRALKELCERQDMLLIVDDIQMGCGR
                     TGGFFSFEEAGIVPDIVTLSKSISGYGLPMSLCLFKPELDIWEPGEHNGTFRGNNPAFV
                     TAAAALQAYWADGQMEKQTLARGEQIEQTLLAVCAEEPTASFRGRGLVWGMEFE"
     gene            5001..5399
                     /locus_tag="DBP20_RS06845"
                     /old_locus_tag="DBP20_06845"
     CDS             5001..5399
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123624.1"
                     /locus_tag="DBP20_RS06845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_06845"
                     /product="ectoine synthase"
                     /protein_id="WP_006123624.1"
                     /sec_met_domain="ectoine_synt (E-value: 1.3e-53, bitscore:
                     178.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRSFSDIENTDRHVKAASGTWESKRIVLAKEKVGFSLHETVLY
                     AGTETSMWYANHIEAVLCTEGEAELTNDETGEKHWITPGTMYLLDGHERHTMRPKTDFR
                     CVCVFNPPVTGREDHDENGVYPLLTEEG"
     gene            5403..6296
                     /gene="thpD"
                     /locus_tag="DBP20_RS06850"
                     /old_locus_tag="DBP20_06850"
     CDS             5403..6296
                     /EC_number="1.14.11.55"
                     /codon_start=1
                     /gene="thpD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156966.1"
                     /locus_tag="DBP20_RS06850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_06850"
                     /product="ectoine hydroxylase"
                     /protein_id="WP_088574003.1"
                     /sec_met_domain="PhyH (E-value: 1.5e-39, bitscore: 135.1,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEVRADLYPSRGAAEMTTPRQDPVIWSAPGAPGPIAAKDLQSY
                     EHDGFLSIEQLITPDEVAAYRAELDRLVADPLIRADERSIVEKQTQNVRSVFEVHKISE
                     VFAGLVRDERVVGRARQILGSDVYVHQSRINVKPGFGASGFYWHSDFETWHAEDGLPNM
                     RTVSVSIALTENFDTNGGLMIMPGSHKSFLGCAGETPKDNYKKSLQMQDAGTPSDEALT
                     KMADRHGIKLFTGKAGSATWFDCNAMHGSGDNITPYARSNVFIVFNSVENAAQEPFAAP
                     IRRPEFIGARDFTPVK"
     gene            6397..7431
                     /locus_tag="DBP20_RS06855"
                     /old_locus_tag="DBP20_06855"
     CDS             6397..7431
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070337.1"
                     /locus_tag="DBP20_RS06855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_06855"
                     /product="VOC family protein"
                     /protein_id="WP_109178107.1"
                     /transl_table=11
                     /translation="MTSHVRHITIDCSDAYGLGTFWAQALGAQISDEDLPGDPEALVET
                     PGAAILFVQVEEPKQTKNRVHLDIQPHDRSRDEEVERLLALGATLVGDHRRPNGRGWAT
                     LADPEGNEFCVECSAAERAALTGTRLPVTADDVTTAVRLAVDVLAKAPADRWEARAGSL
                     EWTCWETAEHLGDDLFAYAVQLGPRTPPLDRDVPFRWAPDREGGPHNAVFADRAAGPAG
                     LLATVEASGALLASMVRTTRPGVRSYHGYGISDPEGFAAMGVVETLVHTHDLAEGLGLE
                     WAPPGALCDRVLARLFPDAPAGGDRWAVLLWATGRAELPGHPRRTAWRWDGRPLEDQTA
                     SSAG"
     gene            complement(7407..>7721)
                     /locus_tag="DBP20_RS06860"
                     /old_locus_tag="DBP20_06860"
                     /pseudo=""
     CDS             complement(7407..>7721)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969934.1"
                     /locus_tag="DBP20_RS06860"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_06860"
                     /product="alkene reductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="EPLGLAYLHILEAAPIRELTLALRKAFSGTLVINVHSEGPTGPGD
                     HTVIDDGIADLISYGALFLANPDLPARLKAGGPFNTPDPSTFFGGDAKGYTDYPALDAV
                     "
     gene            <7714..7962
                     /locus_tag="DBP20_RS06865"
                     /old_locus_tag="DBP20_06865"
                     /pseudo=""
     CDS             <7714..7962
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123628.1"
                     /locus_tag="DBP20_RS06865"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_06865"
                     /product="MarR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="SGSHVRRRPDPADRRAVLVEATDQSCALHTAVEAAWGSLEEHTLA
                     GLDPAERTELVRLLAKVEENLCRETEDCPDRRGVASA"
     gene            complement(8037..9095)
                     /locus_tag="DBP20_RS06870"
                     /old_locus_tag="DBP20_06870"
     CDS             complement(8037..9095)
                     /NRPS_PKS="Domain: Aminotran_5 (19-347). E-value: 1.9e-24.
                     Score: 78.2. Matches aSDomain:
                     nrpspksdomains_DBP20_RS06870_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070339.1"
                     /locus_tag="DBP20_RS06870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_06870"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_109178108.1"
                     /sec_met_domain="Aminotran_5 (E-value: 2.9e-17, bitscore:
                     61.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILAPIQAAAVEFAPEVTYLNTSSWGLLPRRTIAAVKALADENA
                     AGRRVGAGSFEAVEAARVGFARLVGVHPDRVATGSSVTVHVGLVAASLPPGAEVLCPEG
                     EFSSVVSPFALRGDLRMRYAPLADLAGAVRESTALVAFSAVQSADGRVADLGAVRAAAA
                     AHGARTLLDATQAAGWFPVDAGAYDYTVTGGFKFLLCPRGTSFLTVTEEAQDTLPALFA
                     GWVSAGAPWTSNYGPLERLAPTARGFDEPPAFLSYHGAEHSLALLAEVGADALYAHATG
                     LAARLREGLAKLGHKAVPGESAIVAVPGLDGLQPELVEAGIAVSAPAGNLRISCHLYNT
                     EADVDRLLDFLA"
     aSDomain        complement(8055..9038)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DBP20_RS06870_Aminotran_5.1"
                     /evalue="1.90E-24"
                     /label="DBP20_RS06870_Aminotran_5.1"
                     /locus_tag="DBP20_RS06870"
                     /protein_end="347"
                     /protein_start="19"
                     /score="78.2"
                     /tool="antismash"
                     /translation="YLNTSSWGLLPRRTIAAVKALADENAAGRRVGAGSFEAVEAARVG
                     FARLVGVHPDRVATGSSVTVHVGLVAASLPPGAEVLCPEGEFSSVVSPFALRGDLRMRY
                     APLADLAGAVRESTALVAFSAVQSADGRVADLGAVRAAAAAHGARTLLDATQAAGWFPV
                     DAGAYDYTVTGGFKFLLCPRGTSFLTVTEEAQDTLPALFAGWVSAGAPWTSNYGPLERL
                     APTARGFDEPPAFLSYHGAEHSLALLAEVGADALYAHATGLAARLREGLAKLGHKAVPG
                     ESAIVAVPGLDGLQPELVEAGIAVSAPAGNLRISCHLYNTEADVDRL"
     gene            complement(9165..9875)
                     /locus_tag="DBP20_RS06875"
                     /old_locus_tag="DBP20_06875"
     CDS             complement(9165..9875)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019765416.1"
                     /locus_tag="DBP20_RS06875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_06875"
                     /product="DsbA family oxidoreductase"
                     /protein_id="WP_109178109.1"
                     /transl_table=11
                     /translation="MRVEIWSDIACPWCYIGKARFEKGLAEFAHRDEVEVVHRSFELDP
                     SRAKGDTALVIDMLAEKYGRSREEAAAMEADVAANAQSEGLGYRTEGRDHGNTFDIHRL
                     LHLAKARGRQDELLTLAYRANFAEERSVFDDEVLVALAEEAGLAADEARAVLADPEAYA
                     DDVRTDEREAAELGANAVPFFVLDRRYGISGGQPSEVFVQALEQAWKDRPATALTTVGG
                     DAAACDADGACELP"
ORIGIN
        1 tgctgttcaa gatggtggaa cccccacaag agacatggag ccaccggcgc agtccaatgg
       61 gggacatcgc ccgcgccggc ggcctcgact ccgtgaattt ttacgcactg agggtgaact
      121 ggcggatacc tgacgtgagt tcaccccaaa ggggggtttc cgcacgcata ttcgaatctt
      181 tcggcacgtg cgttccctcc ggcctctccg cgtcacccgt ttcacgcggc gggggccgag
      241 gtgcgtggac gggccgggct acatcaacga gccgacggcc gcatccgtca ctgcccgtca
      301 acacaccgcc cggtcagccg atgacccgcc cgttcagcac gatgtgccgg ggcgcggcca
      361 gcacccggac gtccgcgcgc ggatccgcgt cgtacacgac cagatccgcc ggggccccct
      421 cctccaggcc gggccgcccc agccagcgcc tggctcccca cgcggtcgcg gagagtgctt
      481 ccagcggcgg gatgcccgcc ttgaccagct cggcgacctc gcccgcgacc aggccgtgcg
      541 ccagggagcc gcccgcgtcg gtgccgacgt agaccgggat cccggcgtcg tacgcggagc
      601 gcacggtgtc gtagcggcgg tcgtacagct gccgcatatg ggccgaccag cgggggaact
      661 tggcttcgcc gcccgccgcg aggtcgggga aggtggcgat gttgaccagc gtcgggacga
      721 tcgcgacgcc gcgttcggcg aagagaggga tggtgtcctc ggtgaggccg gtggcgtgct
      781 cgatgcagtc gatgcccgcc tccaccagat cgcgcagcga ctcctcggcg aagcagtgcg
      841 cggtgacccg ggcgccgagt cggtgcgcct cggcgatggc cgcctcgacc tcgccgcgcg
      901 gccagcaggc ggtgaggtcc ccggcgtcgc ggtcgatcca gtcccccacg agcttgaccc
      961 agccgtcgcc gcgccgggcc tcctgggcga cgtacgcgac gaggtcgccg ggctcgatct
     1021 cgtgcgcgta gttacggatg tagcggcggg tcctggcgat gtggcggccg gccctgatga
     1081 tcttcggcag gtcctcgcgg tcgtcgatcc agcgggtgtc ggagggcgat ccggcgtccc
     1141 ggatcagcag ggtccccgcc tcccggtcgg tgagcgcctg cttctccgcg gtcgccgcgt
     1201 cgaccggtcc gtgccggtcc aggccgacat ggcagtgggc gtcgacgagg ccgggcagcg
     1261 cccagcccct gaccgtcacc gcgtcgtcgg cgccgggcgg gcgctcgtag gtgatccgcc
     1321 cgtccaccgc ccacagttcg tcgcgcacct cgtccgggcc gaccagcacc cggcccttca
     1381 cccgcagcac cggccgcttc tcccgatcac tcacttcgac cacccgtccg gccggccgtc
     1441 cgaccgctca cccgatcact catacgcggc actgtacgag gcctccggtg ggccgtcggt
     1501 aggctgccag tgcctttcga ccgacggacg aacccgaaga gagccccacc gtgacgcacc
     1561 ccttcctcga tcttcccccg ctgaccgccg gccacttcgc ggcgatcgag cggcgcgtgg
     1621 cccggctcct cgccacggag caggacgtcg tcatcaccca gggcgaggcg ctgctgccgc
     1681 tggagggctg tatccgcagc ggcgcgcggc ccggctcgac cgcgctgaac gtggtcacgg
     1741 gtccgtacgg gcagacgttc ggcaactggc tgcgggactg cggtgcgcag gtcatcgatc
     1801 tcgcggtgcc cttccacacg gcggtgaccg ccggccaggt cgccgaggcg ctggccgagc
     1861 acccggagat cgacttcgtc tcgctggtgc acgcggaggc cgcgaccggc aacaccaacc
     1921 cggtcgcgga gatcggcgag gtggtccggg cgcacggcgc gctgttcatg ctggacgcgg
     1981 tcgcctcggt cggcgccgaa ccgctgctgc cggacgcctg gggcgtcgac ctgtgcgtga
     2041 tcggcgcgca gaaggccatg ggcgggcccg ccggggtctc cgcggtgtcg gtgagcgcgc
     2101 gggcctggga gcggatcgcc gccaacccgg ccgccccgcg ccgctcctac ctctcgctgc
     2161 tggactggaa ggagcgctgg atcgacggcg gccgcacggc tctgccgcac gccccggcgc
     2221 agctggagat gctgggcctg gaggcgtgtg tggcccggat cgaggacgag ggcctggaga
     2281 cggtgatggc ccggcacgcc tcggccgccg cggcgacccg ggccggagcg gtggcgctgg
     2341 gcggcggtct cgagccgtac gtccacgagg ctcgggacgc ggccccggtg gcgacgacgc
     2401 tgcgcgcccc ggcggggacg gacgcggccg cgctggtcgc ggcggcactg gcggcggacc
     2461 ccgcgctgcc gctggtcgcg ggcggcgggg cgctgtccaa ggagatgatc cgggtcaacc
     2521 attacggggc ggatgcgacg cggggcgcgg tgctgtcctc gctcgcggct ctgggggcgg
     2581 cgctgaccga tgcgggccga caggtcgata tcgaggctgc ccgccgggct gtttcgaaaa
     2641 cctggccgag ccgataaatt acacaatgcg ggaagctgtt tttaggaaaa cagcttcccg
     2701 cattcttatg cccgcttttc tgtaacctaa acgcaccagt tttcccgcga atccgacttc
     2761 gcgattcggg tgcgtaccga gagagttacg accttgtgac cgactccaca agctcggcgt
     2821 tatgcccgat aaattcagga cataaggttg gaaatcgcct ccgattcagt gggggtctcg
     2881 cgcacgcctg ataacacatg ggcgcccgct gcccaacccc ttacgtcgat gcaatttcca
     2941 aatttgctgg gtaaattcaa tttcatgacc gccgcaccag cagatcttgc ccgtgcccga
     3001 agcgaattcc tcagtatcga tgcgccgcga gtggaggacg gagccgcgat ctggcgcatt
     3061 gcccgcgact cccaggtcct ggacctgaac tcctcgtaca gctacctgct gtggtgccgt
     3121 gacttcgccg cgacctccgt cgtcgcccgt ggcgagagcg gcgagcccat cgccttcgtg
     3181 acgggctaca tccggcccga ccgcccccag accctcgtcg tctggcaggt ggccgtcgac
     3241 gcggcccacc gcggcaaggg gctggccgcc acgctgctgg acgcgctgac cgcccgggtc
     3301 gccgccgacc agggtctgtc gtccgtggag acgacgatca ccccggacaa caccgcctcc
     3361 gaccggctgt tcacgtccta cgccgagcgg cacgacgtgg cgctggagca ggaggtcctc
     3421 ttcgacggcg atctgttccc cgaagggacc cacctgcccg aggtgctcta ccggatcggc
     3481 ccgttcgcca cctgagcccg cccgggcaca ctcggcgcac ccgacccgtg cgcccggccc
     3541 ccacgacttt tcgcgccggc cgaccacccg gcgcggtccc ggccgcatcc gtgcggcggg
     3601 gagcacgaga ccaccgcccg tcacaccccc tcacgcagga gacccgctgt gaccatcacc
     3661 ccgcccgaac tgagtgtctt cgagaccctg gagtccgagg tccggagcta ctgccgcggc
     3721 tggcccgccg tcttcgaccg tgcgcagggc gcccggctga ccgacgagga cggccactcc
     3781 tacctggact tcttcgccgg ggccggctcg ctcaactacg gccacaacaa cccggtcctg
     3841 aaacgagcgc tgatcgacta catcgagcgc gacggcatca cccacggcct ggacatggcg
     3901 accaccgcca agcgcgcgtt cctggagacg ttccagaacg tgatcctgcg cccgcgcgac
     3961 ctgccgtaca aggtgatgtt ccccggcccg accggcacca acgccgtcga gtcggcgctg
     4021 aagctggcgc gcaaggtcaa gggccgcgag tccgtcgtct cgttcaccaa cgccttccac
     4081 ggcatgtcgc tgggctcgct cgccgtcacc ggcaacgcct tcaagcgcgc cggggccggc
     4141 atcccgctgg tgcacggcac cccgatgccg ttcgacaact acttcgacgg tacggtcccc
     4201 gacttcctgt ggttcgagcg gctgctggag gaccagggct ccgggctgaa caagcccgcc
     4261 gccgtgatcg tggagaccgt ccagggcgag ggcggcatca acgtcgcccg cgccgagtgg
     4321 ctgcgcgcgc tcaaggagct gtgcgagcgc caggacatgc tgctgatcgt cgacgacatc
     4381 cagatgggct gcggccggac cggcggcttc ttctccttcg aggaggccgg catcgtcccg
     4441 gacatcgtca cgctgtcgaa gtccatcagc ggctacgggc tgccgatgtc gctctgcctg
     4501 ttcaagccgg agctggacat ctgggagccg ggcgagcaca acggcacctt ccgcggcaac
     4561 aacccggcct tcgtcacggc cgccgccgcg ctgcaggcgt actgggcgga cggccagatg
     4621 gagaagcaga ccctggcccg cggcgagcag atcgagcaga cgctgctggc cgtctgcgcc
     4681 gaggagccga ccgcgagctt ccgcggccgg ggcctggtgt ggggcatgga gttcgaggac
     4741 ccggcccgcg cctccgcggt ctgcgcccgc gccttcgagc tggggctcct gctggagacc
     4801 tccggcccgc agagcgaggt cgtcaagctg ctgccgccgc tgaccatcac ccccgaagag
     4861 ctggacgagg gcctgcgcac gctggcccgc tccgtccgcg agacggcctg acccggtact
     4921 gccggggcag gtggaagaag agaggccccg ggctgtgacg cccggggccc gtgcagagaa
     4981 gagaaaggca accgctcacc gtgatcgtcc gatcgttcag tgacatcgag aacaccgacc
     5041 ggcatgtgaa ggccgcgtcc ggcacctggg agagcaagcg catcgtgctc gccaaggaga
     5101 aggtgggctt ctcgctccac gagaccgtgc tgtacgcggg cacggagacc tccatgtggt
     5161 acgcgaacca catcgaggcg gtgctgtgca ccgagggcga ggccgagctc accaacgacg
     5221 agaccggcga gaagcactgg atcacgcccg gcacgatgta cctgctggac gggcatgagc
     5281 ggcacaccat gcggcccaag acggacttcc gctgcgtgtg cgtcttcaat ccccccgtca
     5341 ccggacggga ggaccatgac gagaacggtg tctacccact gctgaccgag gagggctgaa
     5401 ccatgaccac cgaagtacgc gccgatctgt acccctcgcg cggcgccgcc gagatgacca
     5461 ctccccgcca ggacccggtc atctggtccg cgccgggcgc accgggtccg atcgccgcca
     5521 aggacctgca gagctacgag cacgacggct tcctcagcat cgagcagctg atcacgccgg
     5581 acgaggtcgc cgcctaccgg gcggagctgg accggctggt cgccgacccg ctgatccgcg
     5641 ccgacgagcg ctccatcgtg gagaagcaga cgcagaacgt acggtccgtc ttcgaggtcc
     5701 acaagatcag tgaggtcttc gccgggctgg tccgcgacga gcgggtggtg ggccgggccc
     5761 gccagatcct cggctcggac gtgtacgtcc accagtcccg gatcaacgtg aagccgggct
     5821 tcggggcctc gggcttctac tggcactcgg acttcgagac gtggcacgcg gaggacggtc
     5881 tgccgaacat gcggacggtc tccgtgtcga tcgcgctgac ggagaacttc gacaccaacg
     5941 gcgggctgat gatcatgccc ggttcacaca agtcgttcct cggctgtgcg ggcgagacgc
     6001 cgaaggacaa ctacaagaag tcgctccaga tgcaggacgc cggcaccccg tccgacgagg
     6061 cgctgacgaa gatggccgac cgccacggca tcaagctctt cacgggcaag gccggttcgg
     6121 cgacctggtt cgactgcaac gccatgcacg gttcgggcga caacatcacc ccgtacgcgc
     6181 gcagcaacgt cttcatcgtc ttcaacagcg tggagaacgc ggcacaggag cccttcgcgg
     6241 ctccgatccg ccgcccggag ttcatcgggg cgcgggactt caccccggtg aagtagcgcg
     6301 acgcgcagac gggaggggcc gggacggtac gccgtcccgg cccttcgcgc gtaactcgct
     6361 ggaccggggc ccgcgtcggc ggagagggtg tccgccatga cttcccatgt acgccacatc
     6421 acgatcgact gttccgacgc ctacggactc ggcaccttct gggcccaggc gctcggcgcc
     6481 cagatctccg acgaggacct ccccggtgat ccggaggcgc tggtcgaaac gcccggcgcg
     6541 gcgatcctct tcgtacaggt ggaggagccc aaacagacca agaaccgcgt ccatctcgac
     6601 atccagccgc acgaccgctc ccgcgacgag gaggtcgagc ggctgctcgc gctcggcgcg
     6661 accctcgtcg gcgaccaccg caggccgaac gggcggggct gggcgacgct cgccgacccc
     6721 gagggcaacg agttctgtgt ggagtgcagc gcggccgagc gggctgcgct gaccgggacc
     6781 cggctgccgg tgaccgccga cgatgtgacg accgccgtgc gcctcgcggt ggacgtactg
     6841 gcgaaggccc cggcggaccg ctgggaggcc cgggcgggct cgctggagtg gacctgctgg
     6901 gagacggcgg agcacctggg cgacgatctg ttcgcctacg cggtgcagct gggaccccgg
     6961 acgcctccgc tggaccgcga cgtgcccttc cggtgggcgc cggaccggga gggcggtccg
     7021 cacaacgcgg tcttcgccga ccgggcggcc gggcccgccg ggctgctggc gacggtggag
     7081 gcgagcgggg cgctgctggc ctcgatggta cggacgacgc ggccaggggt gcgctcgtac
     7141 cacgggtacg ggatctccga cccggagggc ttcgccgcga tgggtgtggt ggagaccctc
     7201 gtgcacaccc atgacctggc ggagggtctg ggccttgagt gggcgccgcc cggcgcactc
     7261 tgcgaccggg tgctggcccg gctcttccct gacgcgccgg cgggcggcga ccggtgggcc
     7321 gtcctgctgt gggccaccgg ccgcgccgaa ctgccgggcc acccgcgccg caccgcgtgg
     7381 cggtgggacg ggcggcccct ggaggatcag acggcgtcga gcgccgggta gtcggtgtag
     7441 cccttggcgt cgccgccgaa gaaggtcgac gggtcggggg tgttgaacgg gccgcccgcc
     7501 ttcagccggg cgggcaggtc cgggttggcg aggaagagcg ccccgtagga gatcaggtcg
     7561 gcgatgccgt cgtcgatcac cgtgtggtcg ccgggaccgg tggggccctc ggagtgcacg
     7621 ttgatgacga gggtgccgga gaaggccttg cgcagcgcga gagtcagctc acggatcggg
     7681 gcggcctcca ggatgtgcag ataggcgagg ccgagcggct cgcatgtgcg ccgccgcccc
     7741 gacccggccg accggcgggc cgtgctggtc gaggcgacgg accagagctg cgcgctgcac
     7801 accgcggtgg aggccgcctg gggcagcctg gaggagcaca cgctcgcggg tctggacccg
     7861 gccgagcgca cggagctggt gcggctcttg gcgaaggtcg aggagaacct ctgccgggag
     7921 accgaggact gccccgaccg gcgcggggtc gcgtccgcct gagccctgct cgtacagcct
     7981 gagccgtacg cgcacagcct gagcccactc gtacagcctg atccgcgccc gtacgctcag
     8041 gccaggaagt ccagcagccg gtccacatcg gcctcggtgt tgtagaggtg gcaggagatc
     8101 cgcagattcc cggcgggggc ggagacggcg atcccggcct ccaccagctc gggctggagc
     8161 ccgtcgagcc ccggtacggc gacgatcgcc gactccccgg ggacggcctt gtgcccgagc
     8221 ttcgcgaggc cctcccgcag ccgggccgcg agcccggtgg cgtgcgcgta cagggcgtcg
     8281 gcgccgacct ccgcgagcag ggcgagggag tgctcggccc cgtggtacga gaggaaggcg
     8341 ggcggctcgt cgaagccccg ggcggtgggg gcgaggcgct ccagcgggcc gtagttgctc
     8401 gtccaggggg cgccggcgga gacccagccc gcgaaaaggg ccgggagggt gtcctgcgcc
     8461 tcctcggtga ccgtcaggaa cgacgtaccg cgcgggcaga gcaggaactt gaagccgccg
     8521 gtgacggtgt agtcgtacgc cccggcgtcc accgggaacc agcccgccgc ctgggtggcg
     8581 tccagcaggg tgcgggcccc gtgcgccgcg gcggcggcgc ggacggcgcc gaggtcggcg
     8641 acccggccgt cggccgactg cacggcggag aaggcgacca gcgcggtcga ctcccggacg
     8701 gctccggcga ggtccgcgag cggcgcgtac cgcatgcgca gatcgccgcg gagcgcgaac
     8761 gggctcacca cggaggagaa ctcgccctcg gggcagagga cttcggcgcc gggcggcagc
     8821 gaggcggcga cgaggccgac atggacggtg acggagctgc cggtggcgac ccggtccggg
     8881 tggaccccga cgagccgggc gaagccgacc cgggcggcct ccacggcctc gaagctgccg
     8941 gcccccaccc ggcggcccgc ggcgttctcg tcggccaggg ccttgacggc ggcgatcgtc
     9001 cggcggggca gcaggcccca actggaggtg ttgaggtagg tgacctcggg cgcgaattcg
     9061 acggctgcgg cttggatggg cgcgaggatc gtcatgcgtc caccctggag ccccctcaac
     9121 ccaaagtcaa ttgcagagag ctaaggggaa ctccaaagaa atacttatgg aagctcgcag
     9181 gccccgtccg cgtcgcaggc cgccgcgtcc ccgccgaccg tggtgagggc ggtggcgggg
     9241 cggtccttcc aggcctgctc cagcgcctgg acgaagacct cggagggctg gccgccggag
     9301 atgccgtacc gccggtcgag gacgaagaac ggcacggcgt tggcgcccag ttcggccgcc
     9361 tcgcgctcgt cggtgcggac gtcgtccgcg tacgcctcgg ggtcggcgag caccgcgcgg
     9421 gcctcgtcgg cggcgagtcc ggcctcctcg gcgagggcga ccagcacctc gtcgtcgaag
     9481 acggaacgct cctcggcgaa gttcgcccgg taggcgaggg tcagcagctc gtcctggcgg
     9541 cccctggcct tggccaggtg cagcagccgg tggatgtcga aggtgttgcc gtggtcacgg
     9601 ccctcggtgc ggtagccgag cccctcggac tgtgcgttgg cggcgacgtc ggcctccatc
     9661 gcggcggctt cctcgcggct gcggccgtac ttctcggcca gcatgtcgat cacgagcgcg
     9721 gtgtcgccct tggcccggga ggggtcgagc tcgaaggacc ggtgcaccac ctcgacctcg
     9781 tcccggtggg cgaactccgc gaggcccttc tcgaagcggg ccttgccgat gtagcaccac
     9841 gggcaggcga tgtcgctcca gatctcgacg cgcatgactc ttcttctctc ccaggctcac
     9901 gagggggcgt gcggagaggc cctccgtacg tcacgtctcc gtgagaacac caaagctgac
     9961 ctggtgattc ccgccccgcg acccgctggc gtccggggcg gaaatcggga aagctcgcgg
    10021 gcatggtctc agtggtgcag aacgtggcga tcgactgtgt gaacgcgtat gagctggcgc
    10081 ggttctggag cgaggtgacc ggccgtccgc tgcacccgga ggcagaaccg ggcatggcgg
    10141 agacacaggt gatgatggcg gagggcccga tgctctactt ccatcaggtc cccgagccga
    10201 agaaggggaa gaaccggctc catctgtgtc tgcgtcccga gacctcgcgc gaggaggagg
    10261 tggagcggct gctggccctc ggcgccaccc tagtcgccga tctccgcgaa ccggacggct
    10321 ccggctgggc ggtgctcgcc gatcccgagg gcaacgagtt ctgcgtgctg cgcagcgagt
    10381 ccgaccgggc cgcgacggc
//
