LOCUS       NZ_KZ819178            22214 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. CS131 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ819178
VERSION     NZ_KZ819178.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS131
  ORGANISM  Streptomyces sp. CS131
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7968990)
  AUTHORS   Malmierca,M., Ceniceros,A., Mendez,C., Salas,J.A. and Olano,C.
  TITLE     Genome analysis of twelve Streptomyces spp. associated with Peruvian
            leafcutter ants
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7968990)
  AUTHORS   Malmierca,M., Ceniceros,A., Mendez,C., Salas,J.A. and Olano,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2018) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 88.88x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003116755.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 09:38:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,994
            CDSs (total)                      :: 6,912
            Genes (coding)                    :: 6,769
            CDSs (with protein)               :: 6,769
            Genes (RNA)                       :: 82
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 41 of 143
            Pseudo Genes (incomplete)         :: 122 of 143
            Pseudo Genes (internal stop)      :: 12 of 143
            Pseudo Genes (multiple problems)  :: 31 of 143
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:40:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 109036
            Orig. end                         :: 131250
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ819178.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Professor JA Salas
            laboratory.
FEATURES             Location/Qualifiers
     region          1..22214
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22214
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22214
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12214](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12214
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(101..892)
                     /locus_tag="DBP20_RS00530"
                     /old_locus_tag="DBP20_00530"
     CDS             complement(101..892)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766343.1"
                     /locus_tag="DBP20_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00530"
                     /product="DUF4389 domain-containing protein"
                     /protein_id="WP_093444624.1"
                     /transl_table=11
                     /translation="MAEGQWSPGRKEADADEFRPVLDIVEPARQRRLTVLLRLLLLIPH
                     FIVLFLLHIAAFFTVIVGWFAALVLGRLPDPVFRFLTGVLGYDMRVSASDMLLIDRYPP
                     FALTPPADYPVQIEVRPTPLNRLAVLFRVFLMIPAAIVQSLAVYGWWALAFVWWLITLC
                     LGRMPRPLFEATAATLRYRMRFSAYVMMLTPAYPKALFGDDDLAVPPEQARSATRPLVL
                     SSAAKWLVVLFLVLGLAGHITSSLTASTTDDTTDTQLVGTP"
     gene            complement(1006..1749)
                     /locus_tag="DBP20_RS00535"
                     /old_locus_tag="DBP20_00535"
     CDS             complement(1006..1749)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382265.1"
                     /locus_tag="DBP20_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00535"
                     /product="VanZ family protein"
                     /protein_id="WP_239475217.1"
                     /transl_table=11
                     /translation="MTAEANPPVRQGTWVRVLVRGLVLAAALAGLVAFSVLLAKVTLTP
                     SPASEDIVTSNLQPGRSLRQYAEDYTFLAACKQAGGNVLLGVPFGLLLPFFVPRRLRMI
                     RTTLLAAVAMAVVELIQGALVQGRAFDIDDVILNTAGALLGYFVLGRRLSHRYYTYAEV
                     PSPVEQRDEPEPTTRPKHTPGKGVRSQLARRKASDSKAGGTKTAGTKAAGAKAAAKKAT
                     GTKGNSATATSAKAPRPLLDRLRGR"
     gene            1848..2348
                     /locus_tag="DBP20_RS00540"
                     /old_locus_tag="DBP20_00540"
     CDS             1848..2348
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971171.1"
                     /locus_tag="DBP20_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00540"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_093444626.1"
                     /transl_table=11
                     /translation="MSAEKKKDLLDEADRLREGGRPEEARERLLALTAEYPDDAEVACR
                     TAWIHDALGLESEAVPYYERALANPGLSAQDRRGSLLGLGSTYRVLGRYGQGVETLRRG
                     VEEFPDDGAMRTFLAMALFNTGEHDEAMRLLLELTAATSQDPYVQQYRRAIEHYAKDLH
                     ETV"
     gene            2502..3197
                     /locus_tag="DBP20_RS00545"
                     /old_locus_tag="DBP20_00545"
     CDS             2502..3197
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491112.1"
                     /locus_tag="DBP20_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00545"
                     /product="YoaK family protein"
                     /protein_id="WP_109181318.1"
                     /transl_table=11
                     /translation="MTGDAPRRGEAALFLLSAASGAADAFVFLCVGQVFAGVMTGNLVL
                     LGASAAGAGEDGVALKVAVALGAYFCGVMAGSLMAGRRGFRVPVLLGAEVVLLGAAAVL
                     WGLGLVTSYGERLGLLALVAVAMGVQGRVRVTPTNYFTGTLTSLAGRVALRELRAGDGW
                     VLGRLAAVVAGAAVAALAERWWSPGAALGAVMMAAGALALETVPGRGGRSRRGKGKPRP
                     DRGNPAGAA"
     gene            complement(3421..3681)
                     /locus_tag="DBP20_RS00550"
                     /old_locus_tag="DBP20_00550"
     CDS             complement(3421..3681)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956431.1"
                     /locus_tag="DBP20_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00550"
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="WP_109177356.1"
                     /transl_table=11
                     /translation="MKSRIHPVSRPVVFRDRAADVAFLTRSTADSGERVEWEDGNAYPV
                     IDVETSSASHPFYTGGTRVLDTAGRVEQFHRRYGAGETSGS"
     gene            complement(3761..3925)
                     /gene="rpmG"
                     /locus_tag="DBP20_RS00555"
                     /old_locus_tag="DBP20_00555"
     CDS             complement(3761..3925)
                     /GO_component="GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpmG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010470368.1"
                     /locus_tag="DBP20_RS00555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00555"
                     /product="50S ribosomal protein L33"
                     /protein_id="WP_032768867.1"
                     /transl_table=11
                     /translation="MARSESRPVVTLRSTAGTGRSYATRKNRRNHPDRLELRKFDSAVG
                     RHVLFREVR"
     misc_feature    3970..3985
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.8"
                     /tool="antismash"
     misc_feature    3972..3986
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.37"
                     /tool="antismash"
     misc_feature    complement(3973..3988)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.58"
                     /tool="antismash"
     misc_feature    4111..4126
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.2"
                     /tool="antismash"
     gene            4281..5711
                     /locus_tag="DBP20_RS00560"
                     /old_locus_tag="DBP20_00560"
     CDS             4281..5711
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956434.1"
                     /locus_tag="DBP20_RS00560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00560"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_109177357.1"
                     /transl_table=11
                     /translation="MPSPLFADRPAPQLPAHDAVDDLIHRTRRLRGDVDAVRRDAVMFD
                     EDDPQLRWQRALCELAVHHLDTLGEHLGQLRAGLPGPRGEASASEDEEAPDGPRAGSLL
                     SRVGSAEWNLLTDESSWSEELYEIFGRPLDSAPLSLDDLPSVLLPEDQPVLTAMVTGCL
                     VDGRPMDGEFRIVRPDGGTRTLHMTGEPVLDGEGCTASMWAVLRDVSELRRSEQAVTRS
                     RASVRREEHIERTEHRMAVELQETVLPPWRGSLRLPPQGPGALDIAAHYLPSASSGLIG
                     GDWYDAMELPDGRTLLTVGDLTGHGIPATSAMAMLLGALRGMAVAGIEPGALMGHLNQV
                     LETSIQPALGSALCCRFDPGTSVLSWAQAGHPAPLLFRGGSGRLLPPPDGILLGAAPQA
                     VFEQDEVRLFPGDVLVLHTDGLTRRGDRGAGPEALLDLAPRFADARTAQECVRGLVEGF
                     GGTERLDDACVLVARIGA"
     gene            complement(5797..7284)
                     /locus_tag="DBP20_RS00565"
                     /old_locus_tag="DBP20_00565"
     CDS             complement(5797..7284)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458453.1"
                     /locus_tag="DBP20_RS00565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00565"
                     /product="hypothetical protein"
                     /protein_id="WP_032768865.1"
                     /transl_table=11
                     /translation="MTGEPNTRLSDLFGLAGWSKGELARMVNRQAAAMGHPQLATDTSR
                     VRRWIDMGESPRDPVPEVLAALFTERLGRVVTIEDLGFGRRGRVGKRRDSGTEHNPDQL
                     PWAPERTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSTIAGPMYDWLHSDPAPAAGAPR
                     TNDPLHADPAGLDRYEAAPVGSDEIAALEHSVEVFRAWDASRGGGLQRKAVVGQLNEVG
                     GMLAYRHPDHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLAKSGSGDETLPRTQAMLRTIEAWAQASMGRGQA
                     MRRTLGEAEELFVSDKSDVPPPSWMQMFDEADMHGMQALAFRTLAEHDPGAAIIAQRHA
                     KQALELRVNGRQRSKIFDYISLASACFIANDPEQADRYARLALVSMGETSSHRTWDRLR
                     EMYRLTGQFAGYAGIQDLREEIELSMPSQKKARGAQI"
     gene            7516..8652
                     /locus_tag="DBP20_RS00570"
                     /old_locus_tag="DBP20_00570"
     CDS             7516..8652
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="DBP20_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00570"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_093444630.1"
                     /sec_met_domain="APH (E-value: 3e-17, bitscore: 62.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRPLRPMGAGGGPYLAPHAGAPVQGPGRARRAAG
                     PGAGPLSGRIDLSGPQGAQVRMAIASVQRICPEFNPVQVLRRSGRSVLIVGTTGRATAV
                     AKCLLDHSPAWTERFRHEIAAYRAFVRHRPPVRVPRLIAADPENCTLVIERMPGRVAAL
                     TRHPAEAPPRADIRAALGAIARVNAWRPPPGLFEAPLDYASRIARYHELGLFTDRDLGD
                     LQKLLHGLAHAGGRQGMGQFCHGDALLSNILLSPTGPVLVDWEHAGWYLPGYDLATLWT
                     VLGDAPVARRQISQLAQARGPAARDAFLVNLMLVLTREIRNYETAVQRTMREAPAVGAG
                     ADRPGALSSGEEQRLLLRRLHDDCAMARRAVRAAVGTR"
     misc_feature    7837..7839
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9145..9825
                     /locus_tag="DBP20_RS00575"
                     /old_locus_tag="DBP20_00575"
     CDS             9145..9825
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971163.1"
                     /locus_tag="DBP20_RS00575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00575"
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_093444631.1"
                     /transl_table=11
                     /translation="MPRISTLRITRSHKIATAVLVAAGSVTAITATGGPSEAQTTATRS
                     SVSVEPVAAAGIPTAKDAAEKAAKENAAKEAAAKKATAKALAEKATAKKAAEKERSEKQ
                     AANRSTERKAVTPKKYANNLDGWIRESLDIMEKKNIPGSYEGLHRNIMRESSGNPNAVN
                     DWDINARNGIPSKGLLQVIQPTFDAYHVKGTPKNLTDPVANITAAANYAADRYGSIDNV
                     DSAY"
     misc_feature    9888..9903
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.35"
                     /tool="antismash"
     misc_feature    complement(9891..9906)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.21"
                     /tool="antismash"
     gene            10001..12214
                     /locus_tag="DBP20_RS00580"
                     /old_locus_tag="DBP20_00580"
     CDS             10001..12214
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382258.1"
                     /locus_tag="DBP20_RS00580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00580"
                     /product="Geosmin synthase"
                     /protein_id="WP_109177358.1"
                     /sec_met_domain="T1TS (E-value: 3.5e-84, bitscore: 282.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFSLPDFYVPYPARLNPHVEAARTHTREWARSMGMLEGSGIW
                     EEKDLEAHDYALLCAYTHPDCSAEALSLVTDWYVWVFFFDDHFLELFKRTPDRAGGKRY
                     LDRLPAFMPMERGAATPEPGNPVEAGLADLWARTVPAMTDDWRARFAESTENLLNESLW
                     ELANIHEGRIANPVEYIEMRRKVGGAPWSAGLVEYAANAEVPAPVAGSRPLRVLRDAFS
                     DAVHLRNDLFSYQREVEDEGENSNGVLVLEKFLGCSAQEAAEAVNDLLTSRLQQFENTA
                     LTELGPLCAEKALDPAQTAAVLAYAKGLQDWQSGGHEWHMRSSRYMNGGGAGEAVAGWG
                     MSAASIRFTLRSEAARARSHSHVPYQRVGPSLLPDFDLPFGTTLSPHLEGARVRLVDWA
                     RRMGILEAQPGVPGSHIWDERRIVAIDLPLCAAGLHPDATPDELDLSSGWLAWGTYGDD
                     WFPVVHGRARDLAGARLANERLSLFMPLDGEGTPEPVNALERSLADLWRRTAAPMDQGA
                     RRAFRTSIESMTESWLWELANQAQNRIPDPVDYVEMRRATFGSDLTMSLCRLGHGRTVP
                     DEVYRSGPMRSLENAAADYACLMNDLFSYQKEIEYEGEVHNGVLVVQNFFGVDYPTGVA
                     IVHDLMNSRLRQFLHVAEVELPVLYDDFGLDAEARKVLAGYVQELKHWIAGILIWHRGC
                     RRYREEDLRQGNDTPWHLGGPRGIGTSAAQVTRMMAQLAGSLG"
     gene            complement(12309..12866)
                     /locus_tag="DBP20_RS00585"
                     /old_locus_tag="DBP20_00585"
     CDS             complement(12309..12866)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060717.1"
                     /locus_tag="DBP20_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00585"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_109177359.1"
                     /transl_table=11
                     /translation="MTPSPTDGRLLKGELRRQELIEATLRVVAREGVAGVSHRAVAREA
                     DQPATAAAYYFKSIDDLLTAALTACMDQDAERMRRLAESADGGPEGLTALAELLGHVMK
                     GPGRLLAEYELYLLAARRPELRTSTGRWLDAIAGYALRYTDDPVRVQILKGVIDGLLLQ
                     GLLTDTPPTAAEFEAVLRHVLL"
     gene            complement(12863..14173)
                     /locus_tag="DBP20_RS00590"
                     /old_locus_tag="DBP20_00590"
     CDS             complement(12863..14173)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458464.1"
                     /locus_tag="DBP20_RS00590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00590"
                     /product="MFS transporter"
                     /protein_id="WP_109177360.1"
                     /transl_table=11
                     /translation="MPNPYGALFRAPGSLAFSAAGLVARMPLSMTGIGIITMLSQMRGQ
                     YGLAGAVSATFTLSMALCGPRISRVVDRRGQSRVLLPATGLSVIAMGVLLLCARYDAPV
                     WTLFVSAAAAGTMPNMAAMVRARWTHLHRGSDRLHTAYSLESVVDELTFVVGPALAVAL
                     STALFPEAGPLVAAVLLTLGVLMFVPQKRTEPPVLRPAADGAPRVSALCGGPLVLLALT
                     LVAGGTIVGTVDVVSVAFAEEQGSPAGAGIVLSVYAIGSAGAGLVFGALRLGVPLPRLL
                     LLSTAGTALTTLPLLLVENIATLSAAVFFSGLFFAPTMIVVMGLVEKTVEPAALTEGMT
                     WAITGLSVGVALGASVSGGMVDRFGPSGGFTVAITAGAATVLLALTAQGPLDRSLRARA
                     EAPAEEGDAKPVPRTPRSHEERHPAPVPPDHDARRAR"
     misc_feature    complement(14129..14131)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    14233..14249
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.27"
                     /tool="antismash"
     gene            complement(14361..14861)
                     /locus_tag="DBP20_RS00595"
                     /old_locus_tag="DBP20_00595"
     CDS             complement(14361..14861)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="DBP20_RS00595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00595"
                     /product="hypothetical protein"
                     /protein_id="WP_003971159.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLYGGRGPAMIIGNLPEGSPARETEEGQVPFEVAQLLLALENDEPIEVVSSEDV
                     PVMQGDNLLIVRRVKLSESRIACVQFDRSDGVLVTIASWDRPITDDLYTLLKPLPAELF
                     QQG"
     misc_feature    14865..14875
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            complement(14963..16129)
                     /locus_tag="DBP20_RS00600"
                     /old_locus_tag="DBP20_00600"
     CDS             complement(14963..16129)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971158.1"
                     /locus_tag="DBP20_RS00600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00600"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_093444635.1"
                     /transl_table=11
                     /translation="MSKEPVAVVGIGQTKHVAARHDVSIAGLVREAAVRALEDAGLSWA
                     DIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMLRVHTAGSVGGSTALVAANLVAAR
                     VHRTVLTLAFEKQSESNAMWGLSLPVPFQQPLLAGAGGFFAPHVRAYMRRTGAPDTVGS
                     LVAYKDRRNALKNPYAHIHDHDLTLEKVQSSPMLWDPVRYSETCPSSDGACAMVLTDRA
                     GAARSPHPPAWVHGGAMRSEPTLFAGKDFVSPQAGKDCAADVYRQARITDPRREIDAVE
                     MYVPFSWYEPMWLENLGFADEGEGWKLTEAGVTELDGDLPVNPSGGVLSTNPIGASGMI
                     RFAEAALQVRGRAGEHQIDGATRALGHAYGGGSQFFAMWLVGAEPPPG"
     gene            complement(16122..17174)
                     /locus_tag="DBP20_RS00605"
                     /old_locus_tag="DBP20_00605"
     CDS             complement(16122..17174)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060725.1"
                     /locus_tag="DBP20_RS00605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00605"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_109177361.1"
                     /transl_table=11
                     /translation="MRDVAIVAFAQSAHRRRTDELSEVDLLMPVLHEVLGATGLKANEI
                     GFTCSGSADYLAGRAFSFTMALDGVGAHPPISESHVEMDGAWALYEAWVKLQTGEADTA
                     LVYSYGKSSPGPVRDVLTRQLDPYYLAPLWPDSVALAALQAQALIDAGDTDEGALAEIA
                     ARNRTAAVDNPYAQLTGDVPAGDPLVNPLRTGDCPPIGDGAAAVVLAAGDTARALCERP
                     AWIRGIDHRIEAHSLGVRDLTDSPSARLAAEHAGAFERPVDTAELHAPFTSQEVVLRKA
                     LGLGDEVRVNPSGGALAANPVMAAGLIRLGEAAARIQRGESDRVLAHATSGPCLQQNLV
                     AVLEGESAHE"
     gene            complement(17175..18122)
                     /locus_tag="DBP20_RS00610"
                     /old_locus_tag="DBP20_00610"
     CDS             complement(17175..18122)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382254.1"
                     /locus_tag="DBP20_RS00610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00610"
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="WP_109177362.1"
                     /transl_table=11
                     /translation="MPDVLSAPLVVEFPFTRSLGPVQRAFLTGLRERTVLGVRTDDGTV
                     LVPPVEYDPVTANELGDLVEVAPTGTVTTWAWNPSPRRDQPLDTPFAWVLVRLDGAGTA
                     LLHVLDAPGPDAVRTGMRVRIRWAATRTGAITDIACFEPYEGEPGPTEPAPHSGEFTDP
                     VTGIVAPARLDYVHTPGRAQSAYIKALEERRTVGERCPACRKVYVPPRGACPTCGVATA
                     EQVEVGPRGTVTTFCIVNIKAKNLDIEVPYVYAHIALDGADLALHGRIAGIPYDQVRMG
                     LRVEPVWSEGARHVDHYRPTGEPDADYDTYKELV"
     gene            complement(18138..18938)
                     /locus_tag="DBP20_RS00615"
                     /old_locus_tag="DBP20_00615"
     CDS             complement(18138..18938)
                     /NRPS_PKS="Domain: ECH (9-258). E-value: 1.4e-53. Score:
                     173.7. Matches aSDomain:
                     nrpspksdomains_DBP20_RS00615_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956444.1"
                     /locus_tag="DBP20_RS00615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00615"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_032778135.1"
                     /transl_table=11
                     /translation="MGGTEHLTVRREGATLVLTLNRPQARNALSLPMLVGLYDGWLAAD
                     ADDTVRSVVLTGAGGAFCSGMDLKALAGDGMAGEEYRERMTADPDLHWKAMLRHHRPRK
                     PVIAAVEGPCVAGGTEILQGTDIRIAGAGATFGLFEVRRGLFPIGGSTVRLPRQIPRTH
                     ALEMLLTGRPYTADEAAAIGLVGRVVPDGTALEEALAVAERVNACGPLAVEAVKASVYE
                     GAELTESEALAAELKRGWPVFATEDAKEGARAFAEKRPPVYRRA"
     aSDomain        complement(18165..18911)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DBP20_RS00615_ECH.1"
                     /evalue="1.40E-53"
                     /label="DBP20_RS00615_ECH.1"
                     /locus_tag="DBP20_RS00615"
                     /protein_end="258"
                     /protein_start="9"
                     /score="173.7"
                     /tool="antismash"
                     /translation="RREGATLVLTLNRPQARNALSLPMLVGLYDGWLAADADDTVRSVV
                     LTGAGGAFCSGMDLKALAGDGMAGEEYRERMTADPDLHWKAMLRHHRPRKPVIAAVEGP
                     CVAGGTEILQGTDIRIAGAGATFGLFEVRRGLFPIGGSTVRLPRQIPRTHALEMLLTGR
                     PYTADEAAAIGLVGRVVPDGTALEEALAVAERVNACGPLAVEAVKASVYEGAELTESEA
                     LAAELKRGWPVFATEDAKEGARAFAEK"
     misc_feature    18993..19008
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.75"
                     /tool="antismash"
     misc_feature    18994..19010
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.71"
                     /tool="antismash"
     misc_feature    18998..19012
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.75"
                     /tool="antismash"
     gene            19106..20731
                     /locus_tag="DBP20_RS00620"
                     /old_locus_tag="DBP20_00620"
     CDS             19106..20731
                     /NRPS_PKS="Domain: AMP-binding (8-439). E-value: 5.1e-67.
                     Score: 218.1. Matches aSDomain:
                     nrpspksdomains_DBP20_RS00620_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382252.1"
                     /locus_tag="DBP20_RS00620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DBP20_00620"
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_093444638.1"
                     /sec_met_domain="AMP-binding (E-value: 4.9e-69, bitscore:
                     231.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYNLADLFESVVDAVPDREALLYVDHPGTGAERRLTYAELDAAA
                     NRIAHHLLDAGIRPGEHLGLHLYNGVEYLQTVLGALKARIVPVNVNYRYVEEELVYLYR
                     DADLAALVFDGEFDERVAAAAPQAPGLRHLVRVGTSAAKAAPGPPAVPFTEAEASGSPD
                     RGFTPRSADDQFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGEPVKTPQELAERVA
                     AGGDGITFFPTPPLMHGTSTLTAFIGFNFGQRVVVHRKFVPEEVLRTIEKEKVTSVSLV
                     GDAMLRPLIDCLKGALRGTDCSSLFSVSSSGAIMSDSVRAEFQELVPTVMLLNNFGSSE
                     SGFNGTATADSGPEKGFRVQVNARTAVVDPVTYEPVAPGEPGRIAQRGHVPLGYYNDPA
                     KTADTFFRRGDERWVLLGDMATVDADGIVTVLGRGSQCINTGGEKVYPEEVEQALKSHA
                     DVYDALVAGVPDERWGNRVAAVVQLREGAAALTLDVVQAHCRTRLAGYKIPRALVLADR
                     IQRSPSGKADYRWAKAVAAEAHRS"
     aSDomain        19130..20422
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DBP20_RS00620_AMP-binding.1"
                     /evalue="5.10E-67"
                     /label="DBP20_RS00620_AMP-binding.1"
                     /locus_tag="DBP20_RS00620"
                     /protein_end="439"
                     /protein_start="8"
                     /score="218.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FESVVDAVPDREALLYVDHPGTGAERRLTYAELDAAANRIAHHLL
                     DAGIRPGEHLGLHLYNGVEYLQTVLGALKARIVPVNVNYRYVEEELVYLYRDADLAALV
                     FDGEFDERVAAAAPQAPGLRHLVRVGTSAAKAAPGPPAVPFTEAEASGSPDRGFTPRSA
                     DDQFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGEPVKTPQELAERVAAGGDGITF
                     FPTPPLMHGTSTLTAFIGFNFGQRVVVHRKFVPEEVLRTIEKEKVTSVSLVGDAMLRPL
                     IDCLKGALRGTDCSSLFSVSSSGAIMSDSVRAEFQELVPTVMLLNNFGSSESGFNGTAT
                     ADSGPEKGFRVQVNARTAVVDPVTYEPVAPGEPGRIAQRGHVPLGYYNDPAKTADTFFR
                     RGDERWVLLGDMATVDADGIVTVLGRGSQCIN"
     CDS_motif       19628..19678
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DBP20_RS00620_0001"
                     /evalue="3.10E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="DBP20_RS00620"
                     /protein_end="191"
                     /protein_start="174"
                     /score="19.8"
                     /tool="antismash"
                     /translation="FIIYTGGTTGMPKGVMW"
     CDS_motif       20273..20320
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DBP20_RS00620_0002"
                     /evalue="3.70E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="DBP20_RS00620"
                     /protein_end="405"
                     /protein_start="389"
                     /score="13.0"
                     /tool="antismash"
                     /translation="VPLGYYNDPAKTADTF"
     misc_feature    20795..20809
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(22175..22190)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.32"
                     /tool="antismash"
ORIGIN
        1 tgggtcccga cgagctcagg gacgccttcg ccggtctggc ccgccgcttc gccgacgcgg
       61 cgggccgggg gcacggtgac tccccggggt ccggcgcccc ttagggcgtg ccgacgagct
      121 gggtgtcggt cgtgtcgtcg gtcgtcgagg cggtcaggga cgaggtgatg tgtccggcga
      181 ggccgagcac caggaagagc acgaccagcc acttcgcggc gctgctcagg accagtgggc
      241 gcgtcgccga ccgcgcctgc tccgggggaa cggcgaggtc gtcgtcgccg aacagcgcct
      301 tggggtaggc gggggtgagc atcatgacgt acgcggagaa acgcatccgg tagcgcaggg
      361 tggccgccgt cgcctcgaac agcggccggg gcatccggcc gaggcagagc gtgatcagcc
      421 accagacgaa ggccagcgcc caccacccgt aaacggcgag gctctgcacg atcgccgccg
      481 ggatcatcag gaagacacgg aagagcaccg cgagccggtt gagcggggtg ggccgcacct
      541 cgatctgcac cgggtagtcg gccggcggcg tgagggcgaa cggcgggtag cggtcgatga
      601 gcagcatgtc gctcgccgag acgcgcatgt cgtagccgag gacaccggtc aggaagcgga
      661 agacggggtc gggcagccgt cccaggacca gggccgcgaa ccatcccacg atgacggtga
      721 agaacgccgc gatgtgcagg aggaacagca cgatgaagtg cgggatgagc agcaggagtc
      781 gcaggagtac ggtcagccgc cgctggcgtg ccggttcgac gatgtccagg acgggccgga
      841 actcgtcggc gtccgcctcc ttgcggcccg ggctccactg gccttcggcc atgtcgctcc
      901 tcctcggcag ggggatccgt acggcatccg cacgcaggac gtgtccccac cgtgcgtccg
      961 gtccgggccg cccgcaaacg gcccggcccg aacgggtgcc cgggctcagc gccctcggag
     1021 gcggtcgagc agggggcggg gggccttggc gctggtggcc gtggcgctgt tgcccttcgt
     1081 gccggtggcc ttcttggcgg cggccttggc accggcagcc ttcgtgcccg cggtcttcgt
     1141 accgccggcc ttcgaatcgg aggccttcct ccgggcgagc tgcgaacgga cgccctttcc
     1201 cggcgtgtgc ttcggccggg tcgtgggctc gggctcatcc cgctgttcga cagggctggg
     1261 tacttctgcg tacgtgtagt agcggtggct gaggcggcgg cccagcacga agtatccgag
     1321 cagcgcgccc gccgtgttga ggatgacgtc gtcgatgtcg aaggcgcgtc cctggaccag
     1381 ggccccctgg atcagctcca cgacggccat ggcgacggcc gccagcagcg tcgtccggat
     1441 catccgcaga cgacgtggca cgaagaaggg gagcaggagt ccgaacggca cgccgagcag
     1501 cacgtttccg cccgcctgct tgcacgcggc gaggaaggtg tagtcctcgg cgtactggcg
     1561 cagcgaccgc cccggctgga ggttggacgt gacgatgtcc tcggaggccg gtgagggggt
     1621 gagcgtcacc ttggcgagca ggacggagaa cgccaccagt ccggccagcg ccgccgccag
     1681 caccagcccg cgtaccagca ctcgtaccca tgtcccctgg cgcacggggg gattcgcctc
     1741 tgctgtcatg ggcgacagat gcccccgccc ggccggaaca cacacccggt cgggccatgg
     1801 agcgaaatct cgtacgaccg tccggctccg cctgcgacga tgtgcgcatg agcgcagaga
     1861 agaagaagga cctgctggac gaggccgacc ggttgcgtga ggggggccgg ccggaggagg
     1921 cacgggaacg gctgctcgcc ctgacggccg agtatccgga cgacgccgag gtggcctgcc
     1981 ggacggcgtg gatccacgac gcgctgggcc tggagtcgga ggcggtgccg tactacgagc
     2041 gcgctctggc caaccccggg ctctcggcac aggaccggcg cggttcgctg ctggggctgg
     2101 gcagtaccta ccgggtcctc ggccggtacg ggcagggggt ggagacgctg cgccggggcg
     2161 tggaggagtt cccggacgac ggtgcgatgc ggacgttcct ggcgatggcg ctgttcaaca
     2221 ccggcgagca cgacgaggcg atgaggctgt tgctggagct gacggccgcg accagtcagg
     2281 acccgtacgt ccagcagtac cggcgggcga tcgagcacta cgcgaaggac ctccacgaga
     2341 ccgtgtgacc cgcgcggcgg ccgggggcgg tggtgcgcgg cgcgccgcgc ggcgggcgac
     2401 gcgccggtcg gggagcggcg cgtgccgaga atgctcgggt gtcctccgct cccccggcgc
     2461 tgccgccgtc ccctccttcc gcctcctcct ccggcgcgtc cctgaccggt gacgcaccgc
     2521 ggcgtggcga ggcggcgctg tttctgctgt ccgcggcttc cggggcggcg gacgcgttcg
     2581 tcttcctgtg cgtggggcag gtcttcgccg gggtgatgac cgggaacctg gtactgctcg
     2641 gggcttcggc cgccggtgcg ggcgaggacg gcgtggcgct gaaggtcgcc gtcgctctgg
     2701 gggcgtactt ctgcggggtg atggcgggct cgctgatggc cgggcggcgg ggcttccggg
     2761 tcccggtgct gctcggggcg gaggtggtcc tgctgggggc ggccgccgtg ctgtgggggc
     2821 tggggctcgt cacgtcgtac ggggaacggc tcgggctgct ggcgctggtg gcggtggcga
     2881 tgggcgtcca ggggcgggtg cgggtgacgc cgacgaacta cttcaccggg actctgacct
     2941 cgctcgccgg ccgggtggcg ttgcgtgagc tgcgcgccgg ggacggctgg gtgctggggc
     3001 ggctggccgc ggtggtggcg ggggcggcgg tcgcggcgct ggccgagcgg tggtggagcc
     3061 ccggggccgc gctcggggcg gtgatgatgg ctgccggtgc gctggccctg gagacggttc
     3121 cggggcgggg cggccgctcc cggcggggca aagggaagcc ccggccggat cgggggaatc
     3181 cagccggggc ggcttgagtg cgggcgtgaa gggcggtcgc ctctcggcgg ggggctccac
     3241 ggggcttcgg cggtgccgat cgtccccatg ggctacaggt gaggcccggg gacgctgtcc
     3301 ccctcacacc cacgtataga tgaacgataa accatcctgg gtgttcccgg gaatccgccc
     3361 ccgcggatgt gatccacggc acggaattcc cggctctccc cctggtcagg ccgcgttcgg
     3421 tcagcttccg gacgtctcgc cggcgccgta gcggcggtgg aactgctcaa cacggcccgc
     3481 cgtgtcgagc acccgggtac cgccggtgta gaacgggtgg ctcgccgacg aggtctccac
     3541 gtcgatgacg gggtaggcgt tgccgtcctc ccactccacg cgctcgccgg agtcggcggt
     3601 cgaacgggtc aggaaggcga cgtcggccgc acggtcacgg aagacgacgg gacgggacac
     3661 ggggtggata cgggacttca tcggtgcgtt ccttcctcac cgcgcgcggc gcgccgcggc
     3721 gtggcggtgg cgtacgggat gccggacctt ttccgagcgg tcagcggacc tcgcggaaca
     3781 ggacgtggcg gccgacggcg gagtcgaact tgcgcagctc cagccggtcg gggtgattgc
     3841 ggcggttctt gcgtgtcgca tagctgcggc ccgttccggc ggtggaccgg agagtgacca
     3901 cgggcctgga ttcactgcgc gccatgggcg cccccttctc tgcctccgac gacccagccc
     3961 cctatcggga atgggattca ttttcgttct ggtggagtaa cgcgggtcgg ccgcgcggca
     4021 ttcccgcccg ccgcacaccc gtcacctgcc acccgtgcgc cactcccgca ccatccgttc
     4081 atcccgcgac gccacgtcaa ctcacctcga acggaagcct gttcggatgt acactcaccc
     4141 cggacagccg ctggcatatg ccagaagcaa ccacgcatcg agtgttgcca aatcccttac
     4201 ggcccgccgc ggcctgtgcg acagtcggta gcggtccacc cttcagaacc ggctaggccg
     4261 cgcctgcaac ggagtacgag atgccgtccc ccctcttcgc ggaccgcccc gcaccgcagc
     4321 ttcccgcgca cgacgccgtc gacgacctga tccaccggac gcgccggctg cgcggggatg
     4381 tggacgccgt gcggcgggac gccgtcatgt tcgacgagga cgacccgcag ctgcgctggc
     4441 agcgcgccct gtgcgagctg gccgtgcacc acctggacac cctcggtgag catctgggcc
     4501 agctcagggc cggtctgccg ggcccgcgcg gcgaggcctc cgcctccgag gacgaggagg
     4561 cgccggacgg cccgagggcc ggttccctgc tgagccgggt gggcagcgcc gagtggaacc
     4621 tcctcaccga cgagtccagc tggtccgagg agctgtacga gatcttcggc aggccgctcg
     4681 actccgcccc cctctccctg gacgacctgc cgtccgtgct gctgcccgag gaccagcccg
     4741 tgctcaccgc gatggtgacg ggctgcctgg tcgacggccg gccgatggac ggcgagttcc
     4801 gcatcgtgcg acccgacggc ggcacgcgca cgctgcacat gacgggcgag ccggtcctcg
     4861 acggcgaggg ctgcaccgcc tccatgtggg cggtcctgcg ggacgtcagc gagctgcgcc
     4921 gcagcgagca ggccgtgacc cgcagccgcg cgtcggtccg gcgcgaggag cacatcgagc
     4981 gcaccgagca ccgcatggcc gtggagctcc aggagaccgt cctgccgccg tggcgcggat
     5041 cactgcgcct cccgccgcag ggccccggcg ccctggacat cgcggcgcac tacctcccct
     5101 ccgcgtcgag cgggctcatc ggcggcgact ggtacgacgc gatggagctg cccgacggac
     5161 gcaccctcct caccgtcggc gacctcaccg ggcacggcat ccccgccacc tcggcgatgg
     5221 cgatgctgct gggcgcactg cggggcatgg ccgtcgccgg catcgagccg ggcgcactca
     5281 tgggacacct gaaccaggtg ctggagacgt cgatacagcc cgcgctgggc agtgccctgt
     5341 gctgccgctt cgaccccgga acctccgttc tctcctgggc gcaggccggt catcccgcgc
     5401 cgctgctctt ccgcggcggt tcgggacggc ttctgccccc gccggacggg atactgctgg
     5461 gcgccgcgcc ccaggccgtg ttcgagcagg acgaggtacg gctgttcccc ggcgacgtgc
     5521 tcgttctgca caccgacggg ctgacccgac gcggcgaccg gggtgcgggc ccggaagcac
     5581 tgctcgacct cgcccctcga ttcgccgacg cccgtacggc acaggagtgc gtccggggcc
     5641 tcgtcgaggg gttcggcggg accgagcgcc tggacgacgc gtgcgtgctg gtcgcccgca
     5701 tcggggcgtg agggaacgcg gacgcatcag ggcatgccgc agaagcgcgg acgtgtcagg
     5761 gcgtgaagca gcccggagcg gcgcggtggg gccggttcag atctgcgcgc ccctggcctt
     5821 cttctggctc ggcatcgaca gctcgatctc ctcgcgcaga tcctggatgc ccgcgtatcc
     5881 ggcgaactga ccggtgagcc ggtacatctc acggagccgg tcccaggtgc ggtgcgagga
     5941 ggtctccccc atcgacacca gcgcgagccg ggcgtaacgg tcggcctgtt ccgggtcgtt
     6001 ggcgatgaag caggcagaag cgagcgagat gtagtcgaag atcttcgacc gctgacgccc
     6061 gttgacccgc agctccagag cctgcttggc gtggcgttgg gcgatgatcg ccgcccccgg
     6121 gtcgtgctcg gccagcgtac ggaaggcgag cgcctgcatg ccgtgcatat cggcctcgtc
     6181 gaacatctgc atccaactgg gcggcgggac atcgctcttg tccgagacga agagctcctc
     6241 ggcctcgccg agggtgcgcc gcatggcctg gccgcgtccc atggacgcct gcgcccaggc
     6301 ctcgatggtg cgcagcatcg cctgcgtacg gggcagggtc tcgtcgccgg aaccggactt
     6361 ggcgagcttc atcaggtcga gtgcgtcgtc ggggcggccc aggtgcacca tctggcgtgc
     6421 cgcgcgggag agcgcctctc cggcgcgtgg ccggtcgccc ccctcgcggg ccgcgtgggc
     6481 ggcgatgacg aagtacttct gggcggtggg ttcgaggccg acgtcgtggg acatccagcc
     6541 cgccaggacg gcgaggttgg cggcgacgcc ccacaggcgg cgctggaggt ggtcggggtg
     6601 gcggtaggcg agcatgccgc ccacctcgtt gagctggccc acgaccgcct tgcgctggag
     6661 tccgccgccc cgggacgcgt cccaggcgcg gaagacctcg accgagtgct ccagcgccgc
     6721 gatctcgtcg gagccgaccg gtgcggcctc gtaccggtcg agaccggcgg gatcggcgtg
     6781 cagggggtcg ttggtccgtg gcgcgccggc cgccggagcg gggtcgctgt gcagccagtc
     6841 gtacatgggg ccggcgatgg ttgagccggc ggcgagcgcg gcgcccgcac ccaccaagcc
     6901 gcgtcggttg agcatgaggt ccattcccgt gaattcggtg aggaccgctg ccgtccgttc
     6961 gggcgcccac ggcagttgat cgggattgtg ttccgtcccg gagtcacgcc gcttccccac
     7021 acgcccgcgt cggccgaacc cgaggtcctc gatggtcacg acacggccga gccgctcggt
     7081 gaacagagcc gccagcactt cgggcacggg atcacggggg gactccccca tgtcgatcca
     7141 gcgcctgaca cgcgaggtgt cggtggccag ctgcgggtgg cccatggccg ccgcctgccg
     7201 gttcaccatt ctcgcgagtt cgcccttgga ccagccggcc aggccgaaca ggtcgctgag
     7261 acgggtgttg ggttctccgg tcacttcaag cccccaggtt ctcggctgac ttgacactaa
     7321 ccccctgtca gatgcgctgt gactattcgc cagggttcgc cagggtccgc cagatggtct
     7381 gccacccgtg acccgttgtc aggtaggagt gcgccacccc gcccggcagc cctaggtact
     7441 ccccagggtg ccgaacggcc gtcggccggg ttggcgcacg taccttgtcg gcgcacgaag
     7501 ggatctgtct cgcccatgta cacagcatcg tcctccgtgt ccgccccgcc ccgtccgctc
     7561 cgcccgatgg gcgcgggcgg cgggccctat ctcgctcctc acgccggtgc gccggtgcag
     7621 ggtccgggcc gggcccgacg ggccgcggga ccgggcgccg gaccgctcag cggaaggatc
     7681 gacctgtccg ggccgcaggg cgcgcaggtg cggatggcca tcgcctccgt ccagcgcatc
     7741 tgccccgagt tcaacccggt ccaggtgctg cgccgcagcg gacgttcggt cctgatcgtg
     7801 ggaacgaccg ggcgggcgac ggccgtggcg aagtgtttac tggaccactc gccggcctgg
     7861 accgagcggt tccggcacga aatagcggcg taccgcgcgt tcgtccggca ccggcccccg
     7921 gttcgggtgc cccggctgat cgcggcggac ccggagaact gcaccctggt gatcgagcgg
     7981 atgcccggcc gggtcgccgc cctcacccgg cacccggcgg aggcgccgcc gcgggccgac
     8041 atccgtgccg ccctgggtgc gatcgcccgg gtgaacgcct ggcggccgcc gcccggactg
     8101 ttcgaggcgc cgctcgacta cgcctcgcgg atcgcccgct accacgagct cggtctgttc
     8161 accgaccgcg acctcggtga cctgcagaag ctgctgcacg gtctggccca cgcgggcggc
     8221 cggcagggca tggggcagtt ctgccacggg gacgccctgc tctccaacat cctgctgtcg
     8281 ccgaccggac cggtgctcgt cgactgggag cacgccggct ggtatctccc ggggtacgac
     8341 ctggcgacgc tgtggacggt gctgggcgac gccccggtgg cgcgccgcca gatcagtcag
     8401 ctggctcagg ccaggggccc ggccgcgcgg gacgcgttcc tggtgaacct gatgctggtg
     8461 ctgactcgcg agatccggaa ttacgagacg gcggtgcagc gcaccatgcg ggaggcgccc
     8521 gcggtgggtg cgggggcgga ccgccccggt gcgctctcct cgggtgagga gcagcggctg
     8581 ctgctgcgga ggctgcacga cgactgcgcg atggcgcgga gggcggtgcg ggcggcggtc
     8641 ggcacccgct gaggcgggac gacgccgacg gagaaaagag ggcgggaccg gaggcctgcc
     8701 cgtcgaggac cgcagtgccc agtcgctgcg ggcccagacc actgtgaaga agaagcgcgc
     8761 tgcgggaccg gtgccgacac accggtcccg cggcgcgctg ttctgcgttc ggtgacgggg
     8821 tgctgaccct gtgccgttcc gggggccctc gcgggtgagg cccgccacga gacccacgtc
     8881 acctacgacg tccggtcgta ggtgtgagcc ctcccgtccg gcgtaacgaa ccgcccatat
     8941 ggctcataaa ttggcatctc acgatgaaga gtagtaaagg cggtcattgc ttcctatgtc
     9001 ggtgcccgct aaccatggat tccggcaggc accgagttcg agcccgcgtc gatcgcccac
     9061 cggcgaccgc ggcccggacg acccggcacc cgccgacgcg gcgcgaaggc cgcgaagccc
     9121 gtcccccata ggaagagctc acgcatgccc cgcatctcca ccctgcgcat cacccgctcg
     9181 cacaagatcg ccaccgccgt gctcgtcgcg gccgggtccg tcaccgccat aaccgccacc
     9241 ggcggcccga gcgaagcgca gaccaccgcg acccggtcct ccgtctccgt ggagccggtc
     9301 gccgccgcgg gcatccccac ggcgaaggac gccgccgaga aggccgcgaa ggagaacgcc
     9361 gccaaggaag ccgcggcgaa gaaggccacc gccaaggcgc tcgccgagaa ggcgaccgcg
     9421 aagaaggccg ccgagaagga gcgctccgag aagcaggccg ccaaccggtc caccgagcgc
     9481 aaggccgtca cgccgaagaa gtacgcgaac aacctcgacg gctggatccg cgagtcgctc
     9541 gacatcatgg agaagaagaa catccccggc tcctacgagg ggctgcaccg caacatcatg
     9601 cgcgagtcca gcggcaaccc gaacgccgtc aacgactggg acatcaacgc gcggaacggc
     9661 attccctcca agggtctcct ccaggtgatc cagcccacct tcgacgcgta ccacgtcaag
     9721 ggcaccccga agaacctcac cgacccggtc gccaacatca ccgccgccgc gaactacgcc
     9781 gcggaccggt acggctcgat cgacaacgtc gactccgcct actgagccgg cccgccgagt
     9841 cggcctgctg agccggcctg ctgagccgac acccccgatg tgccgatgat gtgactaatt
     9901 gtcatcgtgc gtgccccgga tggccgaagg gtagtgctgc gcggacacca ccggtccgcg
     9961 cgattccccg cgcgaaggct tctggaaagg cctgacgcac atggcacagc ccttctcact
    10021 gccggatttc tatgttccgt atccggccag gctcaaccct catgtggaag cggcacgcac
    10081 ccacacccgg gagtgggccc gttccatggg gatgctggag ggatccggca tctgggagga
    10141 gaaggacctg gaggcgcacg actacgccct cctgtgcgcc tacacccatc ccgactgctc
    10201 ggcggaggcg ctcagcctcg tcaccgactg gtacgtgtgg gtcttcttct tcgacgacca
    10261 cttcctggaa ctgttcaagc gcacccccga ccgggcgggc ggcaagcggt atctggaccg
    10321 gctgcccgcc ttcatgccga tggagcgcgg agccgcgaca cccgagcccg ggaatcccgt
    10381 cgaggcgggg ctcgccgatc tgtgggcccg gacggtgccc gcgatgacgg acgactggcg
    10441 ggcccggttc gcggagtcga cggagaacct cctcaacgag tccctgtggg agctcgccaa
    10501 catccacgag ggccgcatcg cgaacccggt ggagtacatc gagatgcgcc gcaaggtggg
    10561 cggcgcgccc tggtccgcgg gcctggtcga gtacgcggcg aacgcggagg tcccggcgcc
    10621 ggtcgccgga tcccggcccc tgcgggtgct gcgggacgcc ttctccgacg ccgtacacct
    10681 gcgcaacgac ctcttctcct accagcgtga ggtggaggac gagggggaga acagcaacgg
    10741 cgtcctggtg ctggagaagt tcctcggctg ctccgcgcag gaggccgccg aagccgtcaa
    10801 cgacctgctg acctcacggc tccagcagtt cgagaacacc gccctcaccg aactcggccc
    10861 tctctgcgcc gagaaggccc tcgacccggc gcagaccgcg gccgtgctgg catacgccaa
    10921 ggggctccag gactggcagt ccggcggcca cgaatggcac atgcgctcca gccgctacat
    10981 gaacggcgga ggcgcgggcg aggccgtggc cggctggggc atgtccgcgg cctccatcag
    11041 gttcaccctc cgctcggagg ccgcgcgggc ccgcagccac agccatgtgc cgtaccagcg
    11101 cgtgggcccc tcactgctgc cggacttcga cctgccgttc ggcacgacgc tcagtccgca
    11161 tctggagggg gcccgggtcc ggctcgtcga ctgggcgcgg cggatgggca tcctggaggc
    11221 ccagccgggg gtgccgggtt cgcacatctg ggacgagcgg cggatcgtcg cgatcgacct
    11281 cccgctgtgc gcggcgggcc tgcacccgga cgcgaccccg gacgaactgg acctgtcctc
    11341 gggctggctg gcctggggga cgtacgggga cgactggttc ccggtggtgc acgggcgggc
    11401 ccgggacctg gcgggcgcgc gcctggccaa cgaacggctg tcgctgttca tgccgctgga
    11461 cggggagggg acgccggagc cggtgaacgc cctggagcgg agcctggccg acctgtggcg
    11521 caggacggcc gcgccgatgg accagggcgc gcggcgcgcc ttccggacct cgatcgagtc
    11581 gatgaccgag agctggctgt gggagctggc gaaccaggcg cagaaccgca tccccgaccc
    11641 ggtggactac gtggagatgc gacgggcgac gttcggttcg gacctgacga tgagtctgtg
    11701 ccggctgggg cacggcagga ccgttccgga cgaggtctac cgcagcggcc cgatgcggtc
    11761 actggagaac gcggcggcgg actacgcgtg cctgatgaac gaccttttct cgtaccagaa
    11821 ggagatcgag tacgagggcg aggtgcacaa cggcgtcctg gtcgtgcaga acttcttcgg
    11881 cgtggactat ccgacgggcg tggcgatcgt ccacgacctg atgaactcgc ggctgcggca
    11941 gttcctgcat gtggccgagg tcgaactccc ggtgctgtac gacgatttcg gcctcgacgc
    12001 cgaggcgcgg aaggtcctgg cgggctatgt gcaggagctc aagcactgga tcgcggggat
    12061 cctgatctgg caccggggct gccgtcgcta ccgcgaggag gacctgcggc aggggaacga
    12121 cactccctgg cacctcggcg gtcccagggg gatcggcaca tcggcggcgc aggtgacccg
    12181 gatgatggcg cagttggcgg gcagcctggg ctagcatccc ggaccctacc gggagcaggg
    12241 tccgccgtgg ggttctcacg gcggaccgcg gggccgggtc cgggcgcgga tcccgaagcg
    12301 gccccgcatc agagcaggac gtgtcgcagc actgcctcga actccgccgc cgtcggcggt
    12361 gtgtcggtca gcagtccctg gaggagcagt ccgtcgatga ctcccttgag gatctgtacc
    12421 cggaccgggt cgtcggtgta gcgcagggcg tatccggcga tggcgtccag ccagcgtccg
    12481 gtggaggtgc gcagctccgg ccgccgggcg gcgagcaggt agagctcgta ctcggcgagg
    12541 agccggccgg ggcccttcat cacgtgcccg aggagttcgg cgagggcggt gagcccctcg
    12601 gggccgccgt cggcgctctc cgccaggcgt cgcatccgtt cggcgtcctg gtccatgcag
    12661 gcggtgaggg cggcggtgag caggtcgtcg atgctcttga agtagtaggc ggcggctgtg
    12721 gcgggctggt ccgcctcgcg tgccaccgcc cggtggctga cgcccgcgac gccctcacgg
    12781 gcgaccaccc ggagggtggc ctcgatgagt tcctgccgtc ggagctcacc cttgagcagg
    12841 cggccgtcgg tcggtgacgg ggtcatcgtg ccctccgggc gtcgtggtcg ggcggtacgg
    12901 gagcggggtg ccgttcctcg tggctgcggg gcgtccgcgg gaccggcttc gcgtccccct
    12961 cctcggcggg cgcctcggcg cgcgcccgca gactccggtc gagcgggccc tgggcggtca
    13021 gcgccaggag caccgtcgcg gcgcccgcgg tgatggccac ggtgaagccg ccggaggggc
    13081 cgaagcggtc gaccatcccg cccgacaccg aggcgccgag cgcgacaccg acgctgaggc
    13141 cggtgatcgc ccaggtcatc ccctcggtga gggcggcggg ctccaccgtc ttctcgacga
    13201 gtcccatcac cacgatcatg gtgggcgcga agaagaggcc ggagaagaag acggccgcgg
    13261 agagcgtggc gatgttctcg acgagcagca ggggaagggt ggtcagggcg gtgccggccg
    13321 tgctgaggag gagcagccgg ggcaggggga cgccgagccg gagggcgccg aacaccagcc
    13381 cggcgccggc cgagccgatc gcgtagacgg agaggacgat gcccgcgccg gccggtgatc
    13441 cctgctcctc ggcgaaggcg acgctcacca cgtcgacggt gccgacgatc gtgccgcccg
    13501 cgacgagggt gagggccagc aggacgagtg gtcccccgca cagcgccgag acgcgcgggg
    13561 cgccgtcggc ggccggccgg aggaccggag gctcggtgcg cttctgcggg acgaacatca
    13621 ggacgccgag ggtgagcagc accgccgcca ccaggggacc ggcctccggg aagagcgcgg
    13681 tgctcagtgc gaccgcgagg gcggggccca ccacgaaggt gagttcgtcg acgaccgatt
    13741 ccagtgagta ggcggtgtgc aggcggtccg agccccggtg gagatgggtc caccgggcgc
    13801 ggaccatcgc cgccatgttg ggcatcgtgc cggccgccgc cgcactgacg aacagcgtcc
    13861 agacaggggc gtcgtagcgg gcgcagagga ggagcacgcc catggcgatg acgctgaggc
    13921 cggtggcggg cagcagtacc ctgctctgcc cccgccggtc gaccacccgc gagatccggg
    13981 ggccgcagag ggccatggac agcgtgaagg tggcggagac ggcccctgcc aggccgtact
    14041 gcccgcgcat ctgggacagc atcgtgatga tcccgatgcc ggtcatcgac agcggcatgc
    14101 gggcgacgag acccgcggcg gagaaggcta aggagcccgg cgccctgaaa agagcgccgt
    14161 aggggttggg catggggacg gacctccgga cgggggaacg acgaacctga acgactgtta
    14221 cacattgaac ggtcgttaca ttttctcacc gtagccgctc ccctgccgtc gatgtcaagg
    14281 gagccgtcgg cgtcaaggga aaaggccgcc cgaacggatt cggacggcct tgcgaccgga
    14341 cggtcttgcg aagggacgtt tcagccttgc tggaacagct ccgcgggcag cggcttgagc
    14401 agggtgtaga ggtcgtcggt gatcggccgg tcccagctgg cgatggtcac gaggacgccg
    14461 tcgctgcggt cgaactggac gcaggcgatc cggctctcgg agagcttgac gcggcggacg
    14521 atcagcagat tgtcgccctg catgacgggg acgtcctcgg agctgacgac ctcgatcggc
    14581 tcgtcgttct ccagggcgag gagcagctgg gccacctcga aggggacctg gccctcctcc
    14641 gtctcgcggg cgggcgagcc ttccggcaga ttgccgatga tcatcgccgg gccccgtccg
    14701 ccgtacaggt cgtagcggag gaagacgccc tgacagctgc cgtcgggggc ggggagcaga
    14761 ccggcgccga ggttgccggg ccagtccccg gggtccatgg ccaggacgtc gaagtccggg
    14821 cccgcgggtg ttgcggcgct acggcggcgg aggaaggaca tgcctgccat gttacgtgtc
    14881 ccggctcacg ttgcggagcc gggcccgggc cgcgcgtgac cgggcccgac gtgtcttctc
    14941 agccggccgg gggctccgct tctcagcccg gcgggggctc ggctcccacg agccacatgg
    15001 cgaagaactg ggacccgccg ccgtaggcgt gaccgagcgc ccgggtggcc ccgtcgatct
    15061 ggtgctcgcc ggctctcccc cggacctgaa gggccgcctc ggcgaagcgg atcatgccgg
    15121 aggcgccgat ggggttggtg gacagcacac cgcccgaggg gttgacgggg aggtcgccgt
    15181 cgagttcggt gacgcccgcc tcggtgagct tccagccctc gccctcgtcc gcgaagccga
    15241 ggttctccag ccacatcggc tcgtaccagg agaacggtac gtacatctcg acggcgtcga
    15301 tctcgcggcg cgggtcggtg atgcgggcct gccggtagac gtcggcggcg cagtccttgc
    15361 cggcctgcgg ggagacgaag tccttgcccg cgaacagggt cggttcgctg cgcatcgccc
    15421 cgccgtggac ccaggcgggc gggtgcgggg agcgggccgc tccggcccgg tcggtgagga
    15481 ccatggcgca ggccccgtcg gacgaggggc aggtctcgga gtagcggacc gggtcccaga
    15541 gcatgggcga ggactggacc ttctccaggg tgaggtcgtg gtcgtggatg tgcgcgtagg
    15601 ggttcttcag cgcgttgcgg cggtccttgt acgcgacgag cgagccgacc gtgtcgggcg
    15661 ctccggtgcg ccgcatgtac gcgcgcacgt gcggggcgaa gaagccgccc gcgccggcca
    15721 gcagcggctg ctggaagggg acgggcaggg agagccccca catggcgttg gactcggact
    15781 gcttctcgaa ggcgagggtg aggacggtgc ggtggacgcg ggcggcgacg aggttcgcgg
    15841 cgaccagggc cgtcgatccg ccgacggagc ccgccgtgtg gacgcggagc atgggtttgc
    15901 cgacggcgcc gagggcgtcg gcgaggtaga gctccggcat catgacgccc tcgaagaagt
    15961 cgggcgcctt gccgatcacg acggcgtcga tgtcggccca gctcagcccg gcgtcctcca
    16021 gggctcggac cgccgcctcg cggacgagtc cggcgatgga gacgtcgtgc cgggcggcga
    16081 cgtgtttggt ctggccgatg ccgacgacgg cgacgggctc cttactcatg agcgctctcc
    16141 ccttccagga cggcgaccag gttctgttgc aggcagggcc cggaggtggc gtgggcgagg
    16201 actcggtcgg actcgccgcg ctggatacgg gcggcggcct cgccgagccg gatgagtccg
    16261 gcggccatga ccgggttggc ggcgagggcg ccgccggagg ggttgacgcg gacctcgtcg
    16321 ccgagcccga gtgccttgcg caggacgact tcctgcgagg tgaacggggc gtgcagctcg
    16381 gcggtgtcga cggggcgttc gaaggctccg gcgtgttcgg cggcgagccg ggcggagggg
    16441 ctgtcggtca ggtcgcggac gccgaggctg tgggcctcga tgcggtggtc gatgccccgg
    16501 atccaggcgg gccgttcgca cagggcgcgg gcggtgtccc cggcggcgag gaccacggcg
    16561 gcggccccgt cgccgatggg cgggcagtcg ccggtgcgca gcgggttcac gagggggtcg
    16621 cccgccggga cgtcgccggt gagctgggcg tacgggttgt ccacggcggc ggtgcggttg
    16681 cgggcggcga tctcggcgag ggctccttcg tcggtgtcgc ccgcgtcgat gagggcctgg
    16741 gcctggaggg ccgcgagggc gacggagtcg ggccagagcg gggcgaggta gtaggggtcg
    16801 agctggcggg tgaggacgtc gcggactggg ccgggcgagg acttgccgta ggagtagacg
    16861 agcgcggtgt ccgcctcgcc ggtctggagc ttgacccagg cttcgtacag cgcccaggcc
    16921 ccgtccatct cgacgtgcga ctcggagatg ggcgggtggg cgccgacgcc gtcgagcgcc
    16981 atggtgaagg agaaggcccg tccggcgagg tagtcggcgg agcctgagca ggtgaacccg
    17041 atctcgttgg ccttgagccc ggtcgcgccc aggacctcgt ggaggacggg catcagcagg
    17101 tcgacctcgg agagttcgtc ggtgcgccgc cggtgcgcgc tctgggcgaa ggcgacgatg
    17161 gccacgtccc gcatctacac cagctccttg tacgtgtcgt agtcggcgtc gggctcgccg
    17221 gtgggccggt agtggtccac atggcgggcg ccctcgctcc agacgggctc gacgcgcagg
    17281 cccatgcgga cctggtcgta ggggattccg gcgatgcgtc cgtgcagggc gaggtccgcg
    17341 ccgtcgaggg cgatgtgggc gtatacgtac gggacttcga tgtcgagatt cttcgccttg
    17401 atgttgacga tgcagaaggt ggtgaccgtg ccgcgcggtc cgacctcgac ctgttcggcg
    17461 gtggcgaccc cgcaggtggg gcaggcgccg cgcggcggca cgtagacctt gcggcaggcg
    17521 gggcagcgtt cgccgacggt acggcgttcc tccagggcct tgatgtaggc gctctgggcg
    17581 cggccggggg tgtggacgta gtcgaggcgg gccggggcga cgatgccggt gacggggtcg
    17641 gtgaactcac cggagtgcgg ggcgggttcg gtggggccgg gctcgccctc gtacggttcg
    17701 aagcaggcga tgtcggtgat ggcgccggtg cgggtcgcgg cccagcggat gcggacgcgc
    17761 atcccggtgc gtacggcgtc gggtccgggt gcgtcgagta cgtgcaggag cgcggtgccg
    17821 gccccgtcga ggcggacgag gacccaggcg aacggggtgt cgagcggctg gtcgcggcgc
    17881 ggggacgggt tccaggccca ggtggtgacg gtgccggtgg gggcgacctc gacgaggtcg
    17941 cccagttcgt tcgcggtcac cgggtcgtac tcgacgggcg gtacgaggac cgtgccgtcg
    18001 tccgtgcgga cgccgaggac ggtgcgttcg cgcagtccgg tgaggaaggc tctctggacg
    18061 gggccgaggg aacgggtgaa ggggaactcg accaccagcg gggcgctgag gacgtcgggc
    18121 atgggtctct cctggggtca ggcgcgccgg tagacgggcg ggcgcttctc ggcgaaggcg
    18181 cgggcgccct ccttggcgtc ctcggtggcg aacacgggcc agccgcgctt gagttcggcg
    18241 gccaaggcct cgctctcggt cagctctgcg ccctcgtaga cggaggcctt gacggcctcg
    18301 acggcgagcg gcccgcaggc gttgacccgt tcggctacgg cgagtgcctc ctccagcgcg
    18361 gtgccgtcgg gcacgaccct gccgacgagc ccgatggcgg cggcttcgtc ggcggtgtac
    18421 gggcgtccgg tgaggagcat ttcgagggcg tgggtgcggg ggatctgacg gggcagccgg
    18481 acggtggagc cgccgatcgg gaagaggccc cggcggacct cgaagagccc gaaggtggct
    18541 ccggctccgg cgatgcggat gtcggtgccc tggaggatct cggtgccgcc cgcgacacag
    18601 gggccctcca cggcggcgat gaccggtttg cgggggcggt ggtggcgcag catcgccttc
    18661 cagtgcagat ccgggtcggc ggtcatccgc tcgcggtact cctcccccgc cattccgtcg
    18721 cccgcgagcg ccttgaggtc catcccggag cagaacgcgc cgcccgcgcc ggtgaggacg
    18781 acggagcgga ccgtgtcgtc cgcgtcggcc gcgagccagc cgtcgtacag gccgacgagc
    18841 atcggcaacg agagcgcgtt cctggcctgt ggtctgttca gggtgagcac cagcgtggcg
    18901 ccttcgcgcc gcacggtgag gtgttccgta ccgcccatga ccgactcctg ttctccggat
    18961 ctggaacagg ttgcaggagg agggggcgca gttcaatagt tttctgacag ctcgtcagat
    19021 tgttgcgacg ccaccccttc ccacttgtgc cgaccggcgc tctaatgacg gccgagtcgc
    19081 cagtcacccg gggtcaggag gaacggtgga gtacaacctt gccgacctgt tcgagtcggt
    19141 cgtcgacgcg gtgcccgacc gtgaggcgct cctgtacgtc gaccaccccg gtacgggcgc
    19201 ggagcgccgg ctcacgtacg cggaactgga cgccgccgcc aaccgcatcg cccaccacct
    19261 gctcgacgcg gggatccggc cgggagagca cctggggctg catctctaca acggggtgga
    19321 atacctccag acggtgctgg gagccctcaa agcgcggatc gtgccggtga atgtcaacta
    19381 ccgttatgtc gaggaggagt tggtctacct ctaccgggac gcggacctgg ctgcgctggt
    19441 cttcgacggc gagttcgacg agcgggtggc ggcggccgcc ccgcaggccc cggggctgcg
    19501 ccatctggtg cgggtgggga cctccgccgc gaaggccgcc cccgggccgc cggccgtgcc
    19561 cttcaccgag gcggaggcgt ccggctcccc ggaccgcggt ttcaccccgc gttccgcaga
    19621 cgaccagttc atcatctaca ccggcggcac gaccggcatg cccaagggcg tgatgtggcg
    19681 tcaggaggac ctgttcttct cgggactggg cggcggcgca ccgaccggag agccggtgaa
    19741 gaccccgcag gaactggccg agcgggtcgc ggcgggcggc gacgggatca ccttcttccc
    19801 caccccgccg ctgatgcacg ggacctccac gctgaccgcg ttcatcggct tcaacttcgg
    19861 ccaacgcgtg gtcgtgcacc gcaagttcgt tccggaagag gtgctgcgga cgatcgagaa
    19921 ggagaaggtc accagtgtgt cgctggtcgg cgacgcgatg cttcgccccc tgatcgactg
    19981 cctgaagggg gcactgcgcg ggacggactg ctcgtcgctg ttctccgtct ccagctccgg
    20041 ggcgatcatg tcggactcgg tgcgcgcgga gttccaggag ctcgtgccga cggtgatgct
    20101 gctgaacaac ttcggctcct ccgagtccgg cttcaacggc acggccaccg ccgactcggg
    20161 ccccgagaag ggcttccggg tccaggtcaa cgcccgtacg gcggtggtgg atccggtgac
    20221 gtacgagccg gtggctcccg gcgagccggg ccgtatcgcc cagcgcggac atgtgccgct
    20281 cggctactac aacgacccgg ccaagaccgc cgacaccttc ttccgccggg gcgacgagcg
    20341 ctgggtgctg ctgggcgaca tggcgaccgt ggacgcggac ggcatcgtca cggtcctcgg
    20401 gcggggctcg cagtgcatca acacaggcgg cgagaaggtg tatccggagg aggtcgagca
    20461 ggcgctcaag tcgcatgcgg atgtgtacga cgcgctcgtc gcgggcgtcc ccgacgagcg
    20521 ttggggaaac cgggtcgccg ccgtggtcca actgcgcgag ggtgcagccg cgttgaccct
    20581 ggacgtggtg caggcccact gccggacccg gctcgccggc tacaagatcc cccgcgcgct
    20641 ggtgctcgcc gaccggatcc agcgctcgcc gagcggcaag gcggactacc ggtgggcgaa
    20701 ggcggtggcg gcggaggccc accggagctg aacggccggg gccgaccgga gctggacgac
    20761 aagggcccac cggggctgct gatctccatg ggcgcgacga cgtcggccat gtatgtgtgc
    20821 cagtgggcga accggtcgct ccgcggcatc gtgtcggtcc ggaacgacct gcgctcagcc
    20881 cgcgccgccg gctccttccc ggtgggtgag accgaacctg cgcagtgccg cgaggaattc
    20941 cccgggccgg tccgcatgga tcaggtgtcc cgcgtcgacg gtgaccagct cggcgtccgg
    21001 tatcgcgcgg accatccgcg cgagctgctc ctggtcgatg tggctgtcgg gcccgccgcc
    21061 gatgacgagg gtgggcacgg tgatctccgg gaagcgttca cggacggccg ggtcggggtt
    21121 gttcaactgg gcgtcgatgt cggggacgac gggccagtcg aagtcgaggt cgccgtcggg
    21181 gcggacagag ggcgcgcggg gcgggtcgag cgggaggagg ggcggcgcgt cctcgatgat
    21241 cagccggccg atcaggcccg gttcccgctg ggccaggagg taggcggcga ccccgcccat
    21301 ggagtgcccg acgacggtcg ccccggcgag gttgcgggct tccaggaagg catggaggtc
    21361 gtcgcggaac atctcgaagg agtagcggcc gggccagtcg ctcagaccgt ggccgcggaa
    21421 gtcgggggcg tacacgcggt ggtcggcggc caggtcctgc gcgatccggg tccaggtctc
    21481 gccggagccc gcccggccgt gcagcaggac gacgggcggg gcatcggggt cgccccacac
    21541 ccggtaggac agccggaccc cgcccgcctg gacgttcagg atctccgggt cgaggaaggc
    21601 ctccaccgta cgggcgaagg ctccggggtc gtcgagccac gggaagtgcc cggccccgcg
    21661 ctggacgacg aactcggcgc ccgggaagag cgcggcgagt tccgtggccc ggtccgggcc
    21721 ggggtggccg tcgtactccc cggcgaggac gaggaccggc acggtcacct cgcgcagggc
    21781 ggcggcggtg gcgacgggat cgaaggcccc ttcctcggcg tagcgcccgc gtgcttccgt
    21841 gttggtctgc ccggcggagg cctcggcatg ggcgcgggcc gcctcgtccc agcggccgta
    21901 ggtgaggggc cggacggcgg gccacagctc ggcgaacggt cccccggcga gcagcgcctc
    21961 ctgggcggcc cgtgcctcgg ggtaccaggg ctcgtcgcgc cgcagttctg cggcctcgcg
    22021 caggtcgtcg tcggtcactt cgatgcccac ggcccgggtg ctgggcgtga ccagggtcag
    22081 ggtgcgcagc cgttccggac ggcgggcggc gtacagcagg gccaggtcgg ctccggcgga
    22141 gtgcgccagt acgtcgatcc gctccaggcc caggtgttcg cgcagggctt cgacgtcgtc
    22201 gacgaggcgg tcgc
//
