LOCUS       NZ_CP023704            24322 bp    DNA     circular CON 27-APR-2024
DEFINITION  Caldibacillus thermoamylovorans strain SSBM chromosome, complete
            genome.
ACCESSION   NZ_CP023704
VERSION     NZ_CP023704.1
KEYWORDS    RefSeq.
SOURCE      Caldibacillus thermoamylovorans
  ORGANISM  Caldibacillus thermoamylovorans
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Caldibacillus.
REFERENCE   1  (bases 1 to 4016170)
  AUTHORS   Cai,L., Zheng,S.W., Shen,Y.J., Zheng,G.D., Liu,H.T. and Wu,Z.Y.
  TITLE     Complete genome sequence provides insights into the
            biodrying-related microbial function of Bacillus thermoamylovorans
            isolated from sewage sludge biodrying material
  JOURNAL   Bioresour Technol 260, 141-149 (2018)
   PUBMED   29625286
REFERENCE   2  (bases 1 to 4016170)
  AUTHORS   Cai,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-SEP-2017) Faculty of Architectural, Civil Engineering
            and Enivironment, Ningbo University, No. 818, Fenghua, Ningbo,
            Zhejiang 315211, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. January-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 125.05x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003096215.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 02:24:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,916
            CDSs (total)                      :: 3,812
            Genes (coding)                    :: 3,697
            CDSs (with protein)               :: 3,697
            Genes (RNA)                       :: 104
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 115
            CDSs (without protein)            :: 115
            Pseudo Genes (ambiguous residues) :: 0 of 115
            Pseudo Genes (frameshifted)       :: 35 of 115
            Pseudo Genes (incomplete)         :: 75 of 115
            Pseudo Genes (internal stop)      :: 20 of 115
            Pseudo Genes (multiple problems)  :: 13 of 115
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:21:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3899225
            Orig. end                         :: 3923547
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023704.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24322
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="3"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..24322
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24322
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:14322](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14322)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    complement(990..1003)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 25.18"
                     /tool="antismash"
     gene            complement(996..2327)
                     /locus_tag="CQJ30_RS18670"
                     /old_locus_tag="CQJ30_18590"
     CDS             complement(996..2327)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020154419.1"
                     /locus_tag="CQJ30_RS18670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18590"
                     /product="hemolysin family protein"
                     /protein_id="WP_192878692.1"
                     /transl_table=11
                     /translation="MDSLWVSIIIILILIFANGIFSMTEIAIVTSRKARLEKLEEDGNK
                     KARYALKLAENPNQLLSTIQIGITLIGVVTGAFGGATIAKQLSVYVDKVAFLHPYSYQL
                     SFILVIGLTTYLSLIIGELVPKRLGMSNPEKVALLVAKPMYYFAKIGKPLIWTLSKSTE
                     FVLKVLGVKPKNQPDVTEEEITQLIEQGVYSGVVEEIEQDMVEQIFYLGDKRLGDILTP
                     RTQIVWIDIEKPFEENIRRMNESNHSRFPVGKGSLDNFLGIIHTKDVFAKLSENKPFDL
                     SECVKDTIVLPEPMKVFQALEALKKSGQHEAIVIDEYGGIEGYVTIYDFMENIVGDLPQ
                     NEDDEEPQIVQRSENTWLADGLISIDQFRRYFDLEDVPSLRGGNNFHTLGGFITMSLGD
                     IPKIKDTVEIEDLILEVVDMDHVRVDKVLITRVEQDEDEEEDDF"
     misc_feature    complement(2545..2564)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 20.87"
                     /tool="antismash"
     gene            2569..2994
                     /locus_tag="CQJ30_RS18675"
                     /old_locus_tag="CQJ30_18595"
     CDS             2569..2994
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012791.4"
                     /locus_tag="CQJ30_RS18675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18595"
                     /product="universal stress protein"
                     /protein_id="WP_108898999.1"
                     /transl_table=11
                     /translation="MSKKIIVPIDDSIHSHHALQFAVKIAKEMDGEIVIVNIQPNLFTP
                     NIQRFISKGEIHQYLQQMAEEILEKASELIRGEDVQVEKIVRIGIPKVEITKLAKELDA
                     FQIVMGSRGMGPVKSAVLGSVSIGVLQLTPCPVTIVP"
     gene            3240..4955
                     /locus_tag="CQJ30_RS18680"
                     /old_locus_tag="CQJ30_18600"
     CDS             3240..4955
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011198029.1"
                     /locus_tag="CQJ30_RS18680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18600"
                     /product="DUF6044 family protein"
                     /protein_id="WP_108899000.1"
                     /transl_table=11
                     /translation="MDFNHALEKRGIFIAYLCIFVFVAPLFLLGEQAHIRVHDNLDSNL
                     AWYKVLVNSGEIFGPVNAVIPQVINGLPRYAYGSEWSGIVWLHALFPTMTAYALSQTIT
                     RVLAFLGMYLLLKEFFIKSDEGRMIRIGVSLAFALTPFWPSGMLCTLGHPLALWAFLKI
                     RSGKDTWKEWLTLGLLPFYSGLVLGFFFFLVAVSFLWLYDLFKTRQINWRFLGSIAFMG
                     SVFLFVEYRLVYSTIFSEDVSHRVEFISSRHDFFRSLRLSLKNFLLGHTHVMTVHTIVI
                     VPILFTALILMIYRKEWRKEKLFIFLLVLNYLLSLWYALWFNNLWIPLKQRYDIFNTFN
                     FARFHFLRPLIIYLSFAIGCSYLWKIGLRRLVKIAVVAQIIVLVPFNEEIHYRFIHHTP
                     TFEEFYAEKLFSDIDQYIGKPKSSYRVASIGLHPAVAQYNGFYTLDTYNNFYPLTYKYQ
                     FRKIIRYELEKNKTLQRYFDEWGSRCYIFVDELGKKFDYKKSSKKRITNLHLDTAVFYE
                     MGGRYLFSSVPIDNAAENHLALVKSFEDDLSYWKIYLYAVTLPEETAKEDIYSG"
     gene            4948..5955
                     /locus_tag="CQJ30_RS18685"
                     /old_locus_tag="CQJ30_18605"
     CDS             4948..5955
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182484.1"
                     /locus_tag="CQJ30_RS18685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18605"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_108899001.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2e-25, bitscore:
                     87.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRLPMLTIIVPCFNEEEVLPETIKQLTGLMNELCEEKLIGKHS
                     RILFVDDGSTDRTWMMIAMESVRNQFVTGIKLARNVGHQKALLAGYLKAREKCDCAISI
                     DADLQDDVGVIKEFMKNYHEGYEIVYGVRKRRDTDSFFKRTTAQGFYRMMKKLGIDLVY
                     NHADFRLLSKRALDELARYPENNLFLRGILPLLGFRSTKVFYDRKERLAGKTKYPLRKM
                     ISFALDGLTSFSVRPIRFITILGIILFSVSILLGSFTIFNHAIFGLNGTVLSLWVLGSL
                     QLIALGTVGEYIGKIFIEVKNRPKYAVEIDLFTKSMMERLDRKMDESYFLKYKS"
     gene            6117..7508
                     /locus_tag="CQJ30_RS18690"
                     /old_locus_tag="CQJ30_18610"
     CDS             6117..7508
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1212:
                     sodium:dicarboxylate symporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017756405.1"
                     /locus_tag="CQJ30_RS18690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18610"
                     /product="L-cystine transporter"
                     /protein_id="WP_108899002.1"
                     /transl_table=11
                     /translation="MDTLLVIINIIALFALIALLFTMQKKHVSFSKRVFTGLGLGIVFG
                     FIIHLLYGTTSNITTQTIDWFNIVGSGYVKLLQMIVMPLVFISIVGAFTKVQLTKNLGK
                     ISFLGIGILLVTTGIAAAIGIASALGFGLQGTELTAGEAENARNEALTENVKMVQDMTI
                     PQQILSFIPANPFDDLTGSRPTSTIAVVIFASFVGIAYLGVRRKQPEPAELFRKIVEAL
                     YAITMRIVTLILRLTPYGVLALMTKMTATSDYGAIVKLGKFVIASYVAIIVMFLVHLLL
                     ISLVKLSPVTYMKKAFPTLTFAFTSRSSAGTLPLNIKTQTDSFGVSEAIANFVGPFSLS
                     IGQNGCAGIYPAMLAIMVAPTAGIDPFDPAFILTVIAVVVISSFGVAGVGGGATFASLI
                     VLSVLNLPIAIVGLLISVEPLIDMGRTALNVSGSMTSGILTSKITGELNKDIYNDKSRN
                     DFVEA"
     gene            complement(7635..9164)
                     /locus_tag="CQJ30_RS18695"
                     /old_locus_tag="CQJ30_18615"
     CDS             complement(7635..9164)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016839345.1"
                     /locus_tag="CQJ30_RS18695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18615"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_041902162.1"
                     /transl_table=11
                     /translation="MNDVITTKNLKEEILKGGHPKYHEKNKEQGKLFVRERLRLLFDDN
                     IEFEDGLYANCLAGDLPADGVVTGIGKIHGRTVCVMANDSTVKAGSWGKRTVEKIIRIQ
                     ETADKLNCPLFYLVDSAGARITDQIEMFPGRRGAGRIFYNQVKLSGKIPQICILFGPSA
                     AGGAYIPAFCDIVIMVEGNASMYLGSPRMAEMVIGEKVDLETMGGAKMHCTISGCGDVL
                     AKTEEEAIRYARNYIRYFPNNYREKPKAEAPKPPANFKKSIDELIPKNQNTPFNMYDLI
                     DCMIDEDSFCEIKKLFAPEIITGLARMDGQPVGIIANQPRVKGGVLFHDSADKAAKFIS
                     LCDAFNIPLIFLADVPGFMIGTQVEKAGIIRHGAKMIFAMSEATVPKITVIVRKAYGAG
                     LYAMAGPAFEPDCCIALTTAQIAVMGPEAAVNAVYANKIAQLPKVEQAAFINQKREEYR
                     EEIDIYRLASELVVDDVIEPNELRSALISRLHAYMSKYQVFTERKHGVSPV"
     misc_feature    complement(9148..9160)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            complement(9241..10023)
                     /locus_tag="CQJ30_RS18700"
                     /old_locus_tag="CQJ30_18620"
     CDS             complement(9241..10023)
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (10-252). E-value: 6e-73. Score:
                     237.1. Matches aSDomain:
                     nrpspksdomains_CQJ30_RS18700_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012292663.1"
                     /locus_tag="CQJ30_RS18700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18620"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_108899003.1"
                     /transl_table=11
                     /translation="MTVNIRFDIYKNWVGVITLTRPEAANAMSIQLLTELSDTLKALHY
                     NRDIRVVLITSEGEKAFCAGADLKERKGMDEHQVKQTVSLIGSTIQQVEDLPQPVIAVL
                     NGVAFGGGLELALACDLRIAGKNAKIGLTETSLGIIPGAGGTQRLPRLIGMGRAKELIY
                     TARRISAAEAYRLGIVEYVYEPEQLMEKAHELALEIAKNAPLSLIQAKTAINHGMDADL
                     KTGLKIEALAYNELLRTADRLEGLQAFQEKRKPQYIGK"
     aSDomain        complement(9268..9993)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CQJ30_RS18700_ECH.1"
                     /evalue="6.00E-73"
                     /label="CQJ30_RS18700_ECH.1"
                     /locus_tag="CQJ30_RS18700"
                     /protein_end="252"
                     /protein_start="10"
                     /score="237.1"
                     /tool="antismash"
                     /translation="KNWVGVITLTRPEAANAMSIQLLTELSDTLKALHYNRDIRVVLIT
                     SEGEKAFCAGADLKERKGMDEHQVKQTVSLIGSTIQQVEDLPQPVIAVLNGVAFGGGLE
                     LALACDLRIAGKNAKIGLTETSLGIIPGAGGTQRLPRLIGMGRAKELIYTARRISAAEA
                     YRLGIVEYVYEPEQLMEKAHELALEIAKNAPLSLIQAKTAINHGMDADLKTGLKIEALA
                     YNELLRTADRLEGLQAFQEK"
     gene            complement(10001..10936)
                     /locus_tag="CQJ30_RS18705"
                     /old_locus_tag="CQJ30_18625"
     CDS             complement(10001..10936)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016839343.1"
                     /locus_tag="CQJ30_RS18705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18625"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_034773410.1"
                     /sec_met_domain="HMGL-like (E-value: 9e-51, bitscore:
                     170.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLPRQVVMKEVGPRDGLQNEKQKILTEDKISFINQLSESGLKYI
                     EVTSFVHPEWIPQLADAKDVLQSIKRNQTITYAALVPNMRGLIRALEAEVDEVSVFLSA
                     SETHNKNNINKTIDETIPILKEVVQEGLKANRSVRGYVSTVIGCPYEGYIEPEQVLKVV
                     DALFNMGVTEVSLGDTIGVAVPTQVEKLLARLFNEYPPNVFAMHFHDTRGTALANIVKS
                     LEMGITIFDSSVGGLGGCPYAKGATGNVATEDLLYLLTEMGIETGVNMDAILASAFFIE
                     EKIGRKLGSKQLEIARGKRGLAHSDSKHTV"
     gene            complement(10948..11160)
                     /locus_tag="CQJ30_RS18710"
                     /old_locus_tag="CQJ30_18630"
     CDS             complement(10948..11160)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016992214.1"
                     /locus_tag="CQJ30_RS18710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18630"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_034773412.1"
                     /transl_table=11
                     /translation="MTKIKASMAGTVWKIVVSEGEEVKAGQDVVILESMKMEIPISAES
                     DGVVKRIIVQEGMFVNEEDDLLEIE"
     gene            complement(11311..12675)
                     /locus_tag="CQJ30_RS18715"
                     /old_locus_tag="CQJ30_18635"
     CDS             complement(11311..12675)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225534.1"
                     /locus_tag="CQJ30_RS18715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18635"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_108899004.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 6.6e-06, bitscore:
                     24.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.3e-13,
                     bitscore: 48.7, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.8e-08, bitscore:
                     31.9, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKKILIANRGEIARRIICTCRKLNIQTVAIYSEADAQSLYVKEA
                     DEAYLVGKPPVAQSYLNIEKIIEIAKESHAEAIHPGYGLLSENATFAQSCLDAGLTFIG
                     PSPEVIASMGSKLEARKKMKEAGIPIIEGMDIALENTEAACQAAEKIGYPIMLKASAGG
                     GGIGMQRIDNSDQLVKAYEGNKKRAESFFGDGTMYIEKLIEDPHHVEIQIIADSYGNVV
                     PLFERECSIQRRNQKVVEEAPSPFISEATRAKMQEAAVRAAKYIGYTNAGTIEFLVDSK
                     QNFYFLEVNTRLQVEHPVTEEILGLDLVAEQIKIAAGESLSFQREDIERKGHAIEVRIY
                     AEDPKTFFPTPGKITGLQLPQGPGIRHECAIEAGTVVTPFYDPMIAKLIAWGKDRNEAC
                     KRLLDALHHYKVGGIKTNIPMLIETVSHELFLKGYPTTSFVENYYLPKIQEIKSK"
     misc_feature    12634..12644
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(12663..12676)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     gene            complement(12697..14322)
                     /locus_tag="CQJ30_RS18720"
                     /old_locus_tag="CQJ30_18640"
     CDS             complement(12697..14322)
                     /NRPS_PKS="Domain: AMP-binding (10-442). E-value: 2.9e-109.
                     Score: 357.3. Matches aSDomain:
                     nrpspksdomains_CQJ30_RS18720_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003352523.1"
                     /locus_tag="CQJ30_RS18720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18640"
                     /product="AMP-binding protein"
                     /protein_id="WP_108899164.1"
                     /sec_met_domain="AMP-binding (E-value: 1e-116, bitscore:
                     387.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFSTIGQLIEEKANQHPNQEALVYTDRDLRLTYQQLDNLSDKVA
                     KGLMALGIEKGDHLAVWTTNVPEWVSLQFATGKMGAPLVTVNTNYRARELEYLLKQSDS
                     TTLILIEQYRDHRFIDTVYEICPELKTSEPGQLQSKRLPKLKNVIVLGENRYDGTFNWS
                     DILNAAEQITDEQLAERKATLHYDDVINIQYTSGTTGFPKGVMLTHYNLINNAVNIAEC
                     MKLTKDDRLCIPVPFFHCFGCVIGTLAITTCGGTMVPVQEFNPEEVLRTVEKEKCTALH
                     GVPTMFISELNLPNFDDFDLSSLRTGVMAGSNCPVEVMKAVIQKMGMNDITICYGQTES
                     SPVITQTRTDDPLELRVETVGRALPNVEVKIVEPGTDTEVPPGAQGELCTRGYHVMKGY
                     YNNPEATKEVIDAEHWLHTGDLATMDENGYVRITGRLKDMIIRGGENIYPREIEEFLYT
                     HPKILDVQVVGVPDDKYGEEVAAFIILREGESASEEEIKNYCRNKIARNKIPKYIIFTD
                     SYPMTASGKIQKFRLREQVNRFIK"
     CDS_motif       complement(12964..13026)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CQJ30_RS18720_0004"
                     /evalue="3.40E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="CQJ30_RS18720"
                     /protein_end="453"
                     /protein_start="432"
                     /score="10.3"
                     /tool="antismash"
                     /translation="TGRLKDMIIRGGENIYPREIE"
     aSDomain        complement(12997..14292)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CQJ30_RS18720_AMP-binding.1"
                     /evalue="2.90E-109"
                     /label="CQJ30_RS18720_AMP-binding.1"
                     /locus_tag="CQJ30_RS18720"
                     /protein_end="442"
                     /protein_start="10"
                     /score="357.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EEKANQHPNQEALVYTDRDLRLTYQQLDNLSDKVAKGLMALGIEK
                     GDHLAVWTTNVPEWVSLQFATGKMGAPLVTVNTNYRARELEYLLKQSDSTTLILIEQYR
                     DHRFIDTVYEICPELKTSEPGQLQSKRLPKLKNVIVLGENRYDGTFNWSDILNAAEQIT
                     DEQLAERKATLHYDDVINIQYTSGTTGFPKGVMLTHYNLINNAVNIAECMKLTKDDRLC
                     IPVPFFHCFGCVIGTLAITTCGGTMVPVQEFNPEEVLRTVEKEKCTALHGVPTMFISEL
                     NLPNFDDFDLSSLRTGVMAGSNCPVEVMKAVIQKMGMNDITICYGQTESSPVITQTRTD
                     DPLELRVETVGRALPNVEVKIVEPGTDTEVPPGAQGELCTRGYHVMKGYYNNPEATKEV
                     IDAEHWLHTGDLATMDENGYVRITGRLKDMIIR"
     CDS_motif       complement(13099..13182)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CQJ30_RS18720_0003"
                     /evalue="5.40E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="CQJ30_RS18720"
                     /protein_end="408"
                     /protein_start="380"
                     /score="28.4"
                     /tool="antismash"
                     /translation="PPGAQGELCTRGYHVMKGYYNNPEATKE"
     CDS_motif       complement(13696..13749)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CQJ30_RS18720_0002"
                     /evalue="1.30E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="CQJ30_RS18720"
                     /protein_end="209"
                     /protein_start="191"
                     /score="24.0"
                     /tool="antismash"
                     /translation="IQYTSGTTGFPKGVMLTH"
     CDS_motif       complement(14065..14103)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CQJ30_RS18720_0001"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="CQJ30_RS18720"
                     /protein_end="86"
                     /protein_start="73"
                     /score="-3.3"
                     /tool="antismash"
                     /translation="FATGKMGAPLVTV"
     gene            complement(14492..15634)
                     /locus_tag="CQJ30_RS18725"
                     /old_locus_tag="CQJ30_18645"
     CDS             complement(14492..15634)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015864021.1"
                     /locus_tag="CQJ30_RS18725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18645"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_108899005.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.4e-39, bitscore:
                     130.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.6e-24, bitscore:
                     83.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.2e-52, bitscore:
                     174.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFELTKEQLMIRDMVRDFAEKEVKPYARELDETHSFRLDTFQKM
                     GKLGLMGIPFPEKYGGSGGDTISYVIAVEEIGKACGGTGLSYAAAVSLGASPIYNFGTE
                     EQKQEWLVPMAQGKALGSFGLTEPNAGSDAGGTRTKAVLDGDEYVINGEKCWITNASYA
                     RQVIITAVTGEREDGKKIITALIVPTDAPGMAITSDYQKMGVRASNTSQIVLENVRVPK
                     ENVLGDPQRGFSQFLNTLDGGRISIAALSVGIAQAAFEKALAYAKERVQFGRSISKFQA
                     IQFKLADMAMEIELARNMLYKAAWLKDNNKPFSKEAAYAKLFASEMGFRVCNQAIQIHG
                     GYGYMAEYDVERHLRDIKLMEIGEGTSEIQRVVISRLIGC"
     gene            complement(15742..16386)
                     /locus_tag="CQJ30_RS18730"
                     /old_locus_tag="CQJ30_18650"
     CDS             complement(15742..16386)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009371632.1"
                     /locus_tag="CQJ30_RS18730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18650"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_041902170.1"
                     /transl_table=11
                     /translation="MEKKALKQRILESSLELFQKNGYHGVTVEQIVEKANTSKGGFYHY
                     FKSKDELLYEIHDVFISYVIKKAQETYDEYETPILRLCGMLHSFIKVFDVYNPYITVFY
                     QESAYLQAAYKEVINEKRDQYRKLIERLIKEGQERGDFRKEVPASIATMSIIGMINWSY
                     KWYKRDGPLSIEEIGDVFRDLIVHSLATEKGLTEANEQNQLLGKREIVSEK"
     gene            complement(16673..17572)
                     /locus_tag="CQJ30_RS18735"
                     /old_locus_tag="CQJ30_18655"
     CDS             complement(16673..17572)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008176292.1"
                     /locus_tag="CQJ30_RS18735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18655"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_034773420.1"
                     /transl_table=11
                     /translation="MELRDLQAFVAVVQYGNFTRAAEALYISQPTLSKSIQKLEASLKA
                     DLLCRTTRQLQLTDIGGVVYEHAQKILHSVLELERSIQDVRNVKSGKIKFGIPPLIGTL
                     FFPEIARKFHEKYPNITLELVEKGAKLIGELVLSGEVDLAIVVLPVENEQFTILPFFEN
                     EFVVYVNAEHPLASRSAVTLPELKNEQFITFTAEFALHDFVIRACQSEGFQPQIAYKSS
                     QWDLIFELIALNLGITILPKAIYAKQTNKNVKIIPFETNQLMWQLGIVTLKDSYQSYAL
                     KELLTVIQTEIWSWQKIF"
     gene            complement(<17810..18022)
                     /locus_tag="CQJ30_RS18740"
                     /old_locus_tag="CQJ30_18660"
                     /pseudo=""
     CDS             complement(<17810..18022)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019720461.1"
                     /locus_tag="CQJ30_RS18740"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18660"
                     /product="multidrug ABC transporter ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIRRFLSYYKPHKKLFLIDFSSAVVVAILELAFPLAVQWFIDSLL
                     PKGNWSTILSVSIALFVLFVINTKMK"
     gene            18172..18981
                     /locus_tag="CQJ30_RS18745"
                     /old_locus_tag="CQJ30_18665"
     CDS             18172..18981
                     /EC_number="2.-.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_transf_8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020155038.1"
                     /locus_tag="CQJ30_RS18745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18665"
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="WP_108899006.1"
                     /sec_met_domain="Glyco_transf_8 (E-value: 6.4e-34,
                     bitscore: 115.4, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINILVTLNANYLHPLKVLLKSLFHHNPKEKFSIYLMHSNLNQYD
                     LDGLHQFITEHQHLFYPIFIDRDYFKEAPVFRHYSTEMYYRLAAHEFLPKTIDRVLYLD
                     PDIVTINPIGSFYRTNFENNLFIASEHEFPTKIVQPINKIRLKTPLTKGYFNTGVLLMN
                     VALMRDLVHLDEIYQYIEKNKFKLVLPDQDVLNALYWDKIKPVDSYRYNYDARYFEFAK
                     FYQSDKNNLEWIKKHTLFIHYCGKDKPWHDDYKGKLGVFYQKFEQMI"
     gene            19131..20366
                     /gene="pepT"
                     /locus_tag="CQJ30_RS18750"
                     /old_locus_tag="CQJ30_18670"
     CDS             19131..20366
                     /EC_number="3.4.11.4"
                     /GO_function="GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="pepT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003250693.1"
                     /locus_tag="CQJ30_RS18750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18670"
                     /product="peptidase T"
                     /protein_id="WP_108899007.1"
                     /transl_table=11
                     /translation="MKDELIKRFTTYVKIDTQSNEDSQTCPSTPGQWDLLNLLVDELKE
                     IGMEEVTIDENGYVFATLPANTNKQVPTIGFLAHVDTATDFTGKNVKPQIVENYDGGDV
                     ILNKELGIVLSPEAFPSLKNYKGQTLITTDGTTLLGADDKAGVAEIMTAMNYLIQHPEI
                     KHGKIRVAFTPDEEIGRGPHKFDVNRFGAKYAYTMDGGPLGELQYESFNAAAAKITIKG
                     NNIHPGSAKGKMVNSIKIGMELNQQLPVREAPEYTEGYEGFYHLLSFHGDVEKTELYYI
                     IRDHDRQKFEAKKENLVKIVDQLRQKYGEDTIGLKLEDQYYNMREKIEPVKEVFENAKE
                     AMERLDITPVIEPIRGGTDGSQLSYMGLPTPNIFAGGENMHGKYEFVSVETMMKATEVI
                     IEIAKIFEEKAK"
     gene            complement(20543..22075)
                     /locus_tag="CQJ30_RS18755"
                     /old_locus_tag="CQJ30_18675"
     CDS             complement(20543..22075)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015370 - solute:sodium symporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018663526.1"
                     /locus_tag="CQJ30_RS18755"
                     /note="Members of the Solute:Sodium Symporter (SSS), TC
                     2.A.21 as described in tcdb.org, catalyze solute:Na+
                     symport. Known solutes for members of the family include
                     sugars, amino acids, nucleosides, inositols, vitamins, urea
                     or anions, depending on the system.; Members of the
                     Solute:Sodium Symporter (SSS), TC 2.A.21 as described in
                     tcdb.org, catalyze solute:Na+ symport. Known solutes for
                     members of the family include sugars, amino acids,
                     nucleosides, inositols, vitamins, urea or anions, depending
                     on the system; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18675"
                     /product="sodium/solute symporter"
                     /protein_id="WP_108899008.1"
                     /transl_table=11
                     /translation="MNTTVVILFLLIVASTLIITYFAAKRTRTANEFYTAGGGLTGWQN
                     GLAIAGDYLSAASFLGIAGSIALTGFDGFFFSIGYLVAYLVVLFIVAEPLRNLGKYTLA
                     DMINARFDAKKVRGVAALSTITIVIFYMIAQLVGAGALIQLLFNIDYWLAVLIVGVMMT
                     IYVLFGGMTATSWVQIIKAVLLMAATVVISFIVLSKFNFNIATMFTKMKTATPLGEDFL
                     NPGVKYKNPLDTISLMTALVLGTAGLPHILMRFFTVKDAQTARSSVMWATWIVGIFYIL
                     TVFLGFGAAAFVGSEKIVEANEAGNMAAPLLAQVLGGDFLMSFVSAVAFATILAVVSGL
                     VLSGASAFAHDIYGQIIKKGKITERQQVLAAKYASLGVAVLSILLALFSQNMNVAFLVS
                     LAFCIAGSANLPVIVYTIFWKRFNTAGAISAMLSGLISALVLVSISPSVFSPTEGAAIF
                     VGNPIFPLTNPAIISVPLGFLGGYLGTVLSGKTDFVRYAEVKFRANTGYRDK"
     gene            complement(22076..22414)
                     /locus_tag="CQJ30_RS18760"
                     /old_locus_tag="CQJ30_18680"
     CDS             complement(22076..22414)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019377637.1"
                     /locus_tag="CQJ30_RS18760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18680"
                     /product="DUF485 domain-containing protein"
                     /protein_id="WP_043988493.1"
                     /transl_table=11
                     /translation="MNHAEQKVEVKKTKFERIIETGKFKELMDQKKKFLVPCTVFFLLF
                     YFALPIMTSYTKLLHQPAFGDINWAWIFAFAQFIMTWTLVTIYMKKSSKFDKLAADVTE
                     EFVKKGGE"
     misc_feature    22550..22563
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.69"
                     /tool="antismash"
     gene            23039..24322
                     /gene="uraA"
                     /locus_tag="CQJ30_RS18765"
                     /old_locus_tag="CQJ30_18685"
     CDS             23039..24322
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="uraA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010630865.1"
                     /locus_tag="CQJ30_RS18765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQJ30_18685"
                     /product="uracil permease"
                     /protein_id="WP_034773433.1"
                     /transl_table=11
                     /translation="MEKNVIQVHEKLPFWESLPLSLQHLFAMFGSTVLVPVLFGVDPGT
                     ILLMNGIGTLIYIFITKGKIPAYLGSSFAFISPVFVVLGRYSGLEGYSYALGGFFAVGV
                     ILVIIGLIIKAVGTGWLDLIFPPAAMGAIVAVIGLELIPTAAQMAGFIAPADATTDWAM
                     DPKTVTVSLLTLAITIVCWVTLRGFLKIIPILIGIISGYIIAFFAGLVDFTTVKEASFI
                     ALPTFYSIKFNWSDILAIIPAALVLVPEHIGHTMVTGNIVGKDLTKDPGLDRSFLGNGI
                     STILSSLVGSTPNTTYGENIGVLAITKVYSTWIIGGAAVIAIFLSFFGKFAALISSIPT
                     AVMGGISLLLFGMIAVSGLRTLVEAKVDYDKSRNLILTCVVLVVGLSGATIQLGSVPLK
                     GMGLATIVAIILSLFFKLLDVLKLSNEK"
ORIGIN
        1 cgaaagtcgt taatgattca aaataaggtg tcggattttc taattctaca attaatgtat
       61 aatcgtcttc cgctcttaca cctaattgat caggtgccat ttctccttta ctgattgcgg
      121 tcgcattttt gataaccccg ttcatcatat acggaccata ttctgaaccg gtggcaggat
      181 caacagctcg tctccaagca tatacgaaat catttgctgt taccggatct ccattttccc
      241 aaacagcatc gtcccggagt ttgaatgtcc aagttaaacc gtccggacta acattatgct
      301 taatggcaat cccgggtacc ggtttcgtgt ccttatccaa gcggtataaa ccttccattg
      361 ttgctgctaa ataaacaaat gaagattcat ccgtagcaag tgccgggtcc atggacggaa
      421 tagcttccgg attgatgaaa ttaagaactt tttcagatcc gctatttgat ttattgtctg
      481 cctttccttt cgtctcttct gccttatcac cggaacatgc tgcaagaaaa gtaatcaaca
      541 tgccggtcaa aagtagtaga gaccatctct tgattttcat taaagttccc ccttttattt
      601 caatataata tcggttaaaa caactgcacc caaattaatc caaacatata cagtattcgg
      661 aatatttaat ctattttaag ctatttaagt ataattttgg ctgcagtttg tgtttaaata
      721 ttataaacta ttatactatt gcttgtaaac tgttttgaca attaatttct tttattatat
      781 tggttgtgaa tttatatatt gttatatgtt gaaagtgatt tttaaatttt tagtgagtgt
      841 caattttatg attgtcacag taaattattc ttacataaca aataaaccca ttccgcgtgt
      901 tttggaatgg gttttatctt attaagaaga tgttaaattc gagctagtta aaaattcagt
      961 ttatacagtc acaagttcgc ccaagttcct tttatttaaa aatcgtcttc ttcctcatct
     1021 tcatcttgtt cgactctggt aattaatact ttgtcgaccc gtacatggtc catatcgaca
     1081 acttccaaaa ttaaatcttc aatttctact gtatctttta tttttgggat atccccgagg
     1141 ctcatcgtta taaaaccgcc gagtgtatgg aaattgttac cgccacgcaa acttggcacg
     1201 tcctccaagt caaagtagcg tcgaaattga tctatggaaa ttaacccgtc cgccaaccat
     1261 gtattttcac ttctttggac aatttgcggt tcttcatcat cttcattttg tggtaagtcc
     1321 ccgacaatat tttccataaa atcataaatg gtcacatagc cctcgattcc gccatattca
     1381 tcaataacaa ttgcttcatg ctgacctgat tttttcaacg cttctaatgc ttggaaaact
     1441 ttcatcggtt ccggcaatac gatggtatct ttgacacact ctgacaggtc gaacggttta
     1501 ttttccgaca acttagcaaa tacatccttt gtatgaatga taccaagaaa attatccaaa
     1561 ctccccttcc cgacaggaaa gcgggaatga ttgctttcat tcattctcct aatattttct
     1621 tcaaacggct tttcaatatc aatccatacg atttgtgtcc gtggtgttaa aatatcgcca
     1681 agccgtttat cacccaaata aaaaatttgc tcaaccatat cctgttcgat ttcctcaact
     1741 acaccgctgt atacaccttg ttcgatgagt tgggtaatct cttcctccgt aacatccggt
     1801 tgatttttcg gctttacccc taatactttt aatacaaatt cggtggattt acttaaggtc
     1861 catataagcg gtttgccaat tttcgcaaaa taatacatcg gtttggcaac aagtaatgcc
     1921 accttttccg gatttgacat tcctaatctc tttggtacaa gttcaccgat gatcaatgac
     1981 aaataggtag ttaacccaat cacaaggata aaactcaatt gatagctata aggatgtaaa
     2041 aatgcaactt tatccacata aacagataat tgttttgcaa ttgtcgcacc gccaaaagca
     2101 cccgtaacga caccgattaa ggtaattccg atttgaatgg tcgacagtaa ctgattcgga
     2161 ttttcagcta attttaaagc atatctcgct ttcttgtttc cgtcctcttc cagtttctcc
     2221 agtctagctt ttcttgatgt tacaatagca atctccgtca tggaaaatat accattagca
     2281 aagattagta taagaataat aataattgaa acccacagac tgtccaaaag tacaatcact
     2341 tctcctttag tcgatactat atgtataaat tttaacctat tcttcaatat tttatcatac
     2401 tcattttttg taatgaaaca ttttgctgct gtaaaaattt tgatggtttt gtgaaatttt
     2461 agagaaataa aagggtttgc agcagaattt gttgaatatt gtcagtaagg agcaactttt
     2521 tgcccttaat ttacttgatg ggagggagag gggctagtcc ccgacaaaat gagcaaaaaa
     2581 ataattgttc cgattgatga ttccattcat tcacatcacg cacttcaatt tgccgtaaag
     2641 attgccaaag aaatggatgg ggaaattgta atcgtaaata tccaaccgaa tttgtttacg
     2701 ccaaatatcc aacggtttat ttcaaagggg gaaattcacc aatatcttca acaaatggct
     2761 gaagaaattt tggaaaaggc ctccgaattg attcgtggag aagatgtgca agttgagaaa
     2821 attgttcgca ttggcattcc aaaagttgaa atcaccaaac tggcaaaaga attagatgcg
     2881 tttcaaatcg tcatgggctc tcgcggcatg ggaccggtta aaagtgccgt cctcggcagt
     2941 gtaagtattg gtgttttgca actcacacca tgcccggtaa cgattgtccc ttagtttttc
     3001 cttaagctgg cgattcgttt ctttaagatt ttattacgat tgtcccactc caatttaggg
     3061 gcaatttttt ttatgggttt aaattcaaag tataagggca ccatgaaaca cttccggaaa
     3121 atagcttgca gtaaaaaaac ctactctaaa accatattta tcctgtatag gaaaaagccg
     3181 gttgggaata gtaaaagggg atttatttca cgaatacgtt tttcaggaag ggatttacaa
     3241 tggattttaa ccacgctttg gaaaagagag gaattttcat tgcctatctt tgtattttcg
     3301 tttttgttgc tccactgttt ctacttggtg aacaggcaca tattcgtgtt catgataatc
     3361 tcgattccaa tcttgcttgg tataaagtac ttgtaaacag cggagaaata tttggaccgg
     3421 tcaatgccgt tattccacaa gtgattaacg gtctacctcg ctacgcctat ggttcagaat
     3481 ggagcggaat tgtctggctc catgcccttt ttccaacaat gaccgcctat gctcttagtc
     3541 aaacaatcac cagagttttg gcctttctcg ggatgtattt gttgctcaaa gaatttttca
     3601 tcaaatcaga cgaggggcgc atgattcgaa tcggtgtttc ccttgctttt gccctaacac
     3661 cgttttggcc atccgggatg ttatgtacac tggggcaccc gctcgcttta tgggcttttt
     3721 taaaaattcg ctcgggtaaa gacacatgga aagagtggtt aacgcttggt ttactccctt
     3781 tttactccgg ccttgtgctc ggttttttct tttttttggt tgccgtaagt tttttatggt
     3841 tatacgactt attcaaaaca agacaaataa actggcgatt tcttggcagt attgctttta
     3901 tgggttctgt ttttcttttc gttgagtacc ggcttgtcta ttcaacaatt ttcagtgaag
     3961 atgttagtca tcgcgtcgaa tttatttctt ctcgccatga tttttttcgg tctctgcgat
     4021 tgtccttaaa aaattttttg cttggtcaca cccatgtaat gaccgtacat acaatcgtca
     4081 ttgtaccgat tctgttcact gcacttatcc taatgattta tcgaaaagag tggcgtaaag
     4141 aaaaattatt tattttttta cttgtactaa actatttgct ttctctgtgg tacgctcttt
     4201 ggtttaacaa tttatggatt ccgctgaagc agaggtatga tattttcaac acgtttaatt
     4261 ttgcccgatt ccattttttg cgaccattga tcatttattt atcttttgcc atcgggtgtt
     4321 cgtatttatg gaaaattggt ttgcggcggc ttgtgaagat agctgtagtt gcacaaatta
     4381 ttgtgctcgt tccttttaat gaagagattc attatcgttt tattcatcat acaccgacat
     4441 tcgaggaatt ttatgccgaa aaactgtttt ctgacatcga ccaatatatc ggtaagccta
     4501 aatcttctta ccgtgtggcc agtatcggac tccatccggc ggtcgctcag tataacggtt
     4561 tttacaccct tgatacatat aataattttt acccgcttac atataaatat cagtttagaa
     4621 aaataataag atatgaattg gaaaaaaata aaactttaca acgctatttt gatgagtggg
     4681 gcagccggtg ctacattttt gtcgatgaac tagggaaaaa atttgattat aagaaaagct
     4741 caaaaaagag gattacaaat ttacacttgg acacagcggt gttttatgaa atgggcgggc
     4801 gctacctatt ttcaagtgtt ccgattgaca atgcagcaga aaatcattta gctttggtaa
     4861 aaagttttga ggacgatcta tcgtattgga aaatttattt atatgccgta acattaccgg
     4921 aagaaacagc taaggaggac atctacagtg gataaacggt taccaatgct gacaattatc
     4981 gtaccttgtt ttaatgaaga ggaagtttta ccggaaacaa tcaaacaatt aaccggatta
     5041 atgaatgagc tatgtgaaga aaaattgatc ggaaaacata gtcgaattct ttttgtcgat
     5101 gatggcagta cagatcgaac ctggatgatg attgccatgg aaagtgtgcg gaaccagttt
     5161 gtgacaggga ttaaattagc ccgcaatgtc ggtcatcaaa aggcgctctt agccggttat
     5221 ttaaaagcaa gggaaaaatg tgattgcgcc atttccattg atgccgattt acaagatgat
     5281 gtcggtgtta tcaaagagtt tatgaaaaat taccatgaag gctacgaaat tgtttatggt
     5341 gttcggaaac gtcgggacac agattccttt tttaaacgaa caaccgccca aggattttat
     5401 cgcatgatga aaaagttagg tattgacctt gtttataacc atgccgattt ccgcttatta
     5461 agtaaacgtg cattagatga gttagcccgt tatccggaga ataatctctt tttaaggggg
     5521 attctccctt tacttggttt ccgatccaca aaagtatttt acgaccggaa agaacggctg
     5581 gccgggaaga caaaatatcc tttgagaaaa atgatttcct ttgctttaga cggacttact
     5641 tcatttagtg tacgccccat ccgatttata acgatacttg gaatcatctt attttctgtc
     5701 agtatacttt taggcagctt tactattttc aaccatgcta tatttggttt gaatggcact
     5761 gtcctttccc tttgggtact cggttctctt caactcattg cccttggaac tgtcggtgaa
     5821 tatattggga aaatttttat tgaagtgaaa aaccgaccaa agtatgccgt tgaaattgat
     5881 ttatttacga aatcaatgat ggagcgactg gatcgaaaaa tggatgaaag ctatttttta
     5941 aagtataaaa gttaattgat aacctttttg ccaaaaatga aaaaatgcat ccccgtcttt
     6001 gttgtaattt tttatctctc actttaccaa tcggatttaa ggtattataa tatatgtacc
     6061 ttaaaaagga aaaactactg atcatttatt aatgagtcag taaagagggg gctatcatgg
     6121 atacgttact tgttattata aatattatcg ctcttttcgc cttaattgct cttttattca
     6181 cgatgcaaaa gaagcatgta tctttttcaa aacgtgtttt taccgggctt gggcttggaa
     6241 ttgttttcgg atttattatc cacttgcttt acggaacaac atcgaatatt acgacgcaaa
     6301 cgattgactg gtttaatatt gtcggttccg gttatgtaaa attattgcaa atgatcgtta
     6361 tgccgctcgt ttttatttct attgttgggg catttacgaa agtgcaattg acgaaaaatc
     6421 ttggcaaaat cagtttcttg ggtattggga ttttactcgt tacaaccggg attgctgcag
     6481 ccatcgggat tgcctcagct ctcggtttcg gtttacaagg gactgaactg actgccggag
     6541 aagctgaaaa tgcacggaat gaagctttga ctgaaaatgt aaaaatggtt caagatatga
     6601 ccattccaca acaaattctt tcatttattc cggcaaatcc ttttgatgat ttgactggtt
     6661 cacgaccgac atcaacaatc gctgtcgtta tttttgcatc ctttgtagga attgcttatt
     6721 taggtgtaag aagaaaacaa ccggagccag ccgaactttt cagaaaaatt gttgaggctt
     6781 tatatgccat taccatgcgg attgtcacat taattttacg gttaacacct tatggcgttt
     6841 tggccttaat gacaaagatg acggccacaa gtgactatgg ggcaatcgta aaactcggta
     6901 aatttgtcat cgcttcttat gttgccatta ttgtcatgtt ccttgttcat ttattattga
     6961 ttagtctggt aaaattaagt ccggttacct atatgaaaaa ggcgtttccg actttgacat
     7021 ttgcctttac atcccgctcc agtgccggga ctttgccact gaacataaaa acacagacag
     7081 acagtttcgg tgtttctgaa gctattgcca atttcgtcgg accgtttagt ttatcaatcg
     7141 ggcaaaacgg gtgtgctggc atttatccgg cgatgcttgc cataatggtt gcaccgactg
     7201 caggaatcga cccgtttgat ccggctttca ttttaacggt cattgccgtt gttgtcatta
     7261 gctcttttgg tgtcgccggt gtcggtggcg gggcaacatt tgcatcgtta attgttttat
     7321 ctgtattgaa tcttcctatt gcgattgtcg gtttattgat ctcggttgaa ccgctgattg
     7381 acatggggcg taccgcttta aacgtaagcg gcagtatgac gtccggtatt ttgacaagta
     7441 aaataaccgg tgaattaaat aaagatatct acaatgataa gagccgcaat gattttgtag
     7501 aagcttaata tagaaagacc agatccgcta aaatagggat ctggtttttt ctttttacga
     7561 aaaatttacc cgataaccat attttgtacg ggacaagtat gcgctcgtta acatgttctt
     7621 tttggatgtt attattaaac cggactaact ccatgttttc gttccgtaaa tacttgatac
     7681 ttcgacatat aagcatgtaa tcgtgatatt aacgcggatc gcaattcatt tggttcaatt
     7741 acatcatcaa cgactaactc ggaagcaagg cgataaatat caatttcttc acgatattct
     7801 tcccgttttt ggttaataaa tgctgcttgt tctacttttg gaagttgcgc gattttattg
     7861 gcatataccg cattgaccgc cgcttccgga cccattaccg ctatttgcgc agttgttaag
     7921 gcaatacagc aatcgggttc aaaagcggga cctgccatgg catataaccc ggcaccatat
     7981 gcttttctaa caataaccgt tatctttgga acggttgctt cactcatggc aaaaatcatt
     8041 ttcgcaccat ggcgaatgat gcctgctttt tctacttgtg tgccaatcat aaatcccggt
     8101 acatctgcca aaaaaatcaa gggaatattg aaagcatcgc ataggctaat gaattttgcc
     8161 gctttatctg ctgaatcgtg gaacaaaacc ccgcctttta cacgcggctg gttcgcaatg
     8221 atgccaaccg gctgaccgtc catacgtgcc aaaccggtaa tgatttcagg tgcaaatagt
     8281 ttctttatct cacagaaaga gtcttcatca atcatacagt caatcaaatc gtacatatta
     8341 aatggcgtgt tttgattttt tggaatcagt tcgtctatac tttttttaaa attagccggc
     8401 ggttttggcg cttctgcttt tggtttttcc cgatagttgt ttgggaagta acggatataa
     8461 tttcgagcat aacgaatggc ttcttcttcg gttttcgcta agacgtctcc acatccggat
     8521 atcgtacaat gcatttttgc cccgcccatt gtctctaaat ctactttttc tccaatgacc
     8581 atttccgcca tacgggggga acctaagtac atggaggcat tgccctctac cataatcaca
     8641 atatcgcaga atgccgggat gtaggcaccg cccgccgcgg atgggccgaa taaaatacaa
     8701 atttgcggaa tctttccgga tagtttaact tgattataaa aaatacgccc tgccccgcgt
     8761 ctgcccggaa acatttctat ttgatcggta atccgggcac ctgctgaatc aactaaataa
     8821 aacaacgggc aatttagttt atctgctgtt tcttgaatac gaataatttt ttcaactgtt
     8881 cttttccccc aggaacctgc ttttactgtt gagtcattag ccataacaca aaccgtgcgg
     8941 ccgtggattt taccaattcc tgttactacg ccatctgcag gtaggtcgcc tgccaaacaa
     9001 tttgcgtata aaccgtcttc aaattcgata ttatcatcga acaatagtct tagtcgttcc
     9061 cggacaaata attttccttg ttctttgttt ttttcgtgat actttggatg accgcctttt
     9121 aaaatttcct cctttaaatt ttttgttgtg ataacgtcat tcatttcgct tccccctttg
     9181 tctgcaactg cctgcaaaat taaacttaat acagcgttaa tttccggtca tatgaagtag
     9241 ctacttacct atatattgcg gctttcgttt ttcttgaaat gcttgtaatc cttcgagcct
     9301 gtccgctgta cgtagaagct cgttataagc aagtgcctca atttttaaac ccgttttcaa
     9361 gtcggcatcc ataccatgat taatggccgt ttttgcctgt attagtgata atggagcatt
     9421 tttggcaatc tcgagcgcca gttcatgggc tttttccatt aattgctcag gttcataaac
     9481 atactccaca atgccaagcc ggtaagcctc ggctgcggaa atccttctag ccgtataaat
     9541 caattccttc gcacgaccca ttccgattaa acgcggcaat ctttgtgttc cacccgcacc
     9601 gggaataatg cccagcgatg tttctgttaa accgattttg gcatttttac cggctatccg
     9661 aagatcacat gcaagtgcta actcaagtcc gccgccaaat gcgaccccgt tcaaaaccgc
     9721 aataaccggc tgcggtaaat cttctacttg ttgaatggtt gagccaataa gtgagaccgt
     9781 ttgctttact tgatgctcat ccatcccttt ccgctctttc aaatcagcac ctgcgcaaaa
     9841 tgctttttcc ccttcactgg taatcagcac gacacgtata tcgcgattat aatgaagtgc
     9901 tttcagtgta tcgctcaatt ctgttaataa ctgaatcgac atggcattgg cagcttcggg
     9961 tcttgttaat gtaatgacac cgacccagtt tttataaatg tcaaaccgta tgtttactgt
    10021 cactgtgggc taaccccctt ttacccctgg caatttctag ttgttttgat cctaattttc
    10081 gaccaatttt ttcttctata aaaaatgcac ttgctaagat tgcatccatg ttcacccctg
    10141 tttcaatgcc catttcagtt aataaatata gcaagtcttc tgtcgctaca tttcctgttg
    10201 ctccttttgc ataaggacaa ccgccaagac caccaactga actgtcaaaa attgttatcc
    10261 ccatttcaag tgattttacg atattggcga gtgccgtacc ccttgtatca tgaaaatgca
    10321 tggcaaaaac attcggtgga tactcgttga ataaacgcgc taataatttc tctacctgcg
    10381 ttggtacagc tacaccaatc gtatccccga gcgatacttc tgtgacaccc atgttaaata
    10441 gggcatcgac aacttttaac acttgctccg gttcaatata tccttcataa gggcaaccga
    10501 ttaccgttga aacatatccc cggacagatc ggttggcttt taacccttct tgaacaactt
    10561 ctttcaaaat agggattgtt tcatctatcg ttttattaat attgttttta ttatgagttt
    10621 cagaagccga taaaaagaca cttacctcat cgacttccgc ttcaagagca cgaataagcc
    10681 ctcgcatatt cgggaccagt gcggcatatg tgattgtttg attacgctta atcgattgaa
    10741 gaacatcctt tgcatcagca agttgcggaa tccattccgg gtgaacaaaa gatgtcactt
    10801 cgatatattt tagccccgat tcacttaact gattaatgaa tgagatttta tcttcagtta
    10861 aaattttttg tttttcattt tgaagtccat ctctcggtcc tacttctttc atgacaactt
    10921 gacgtggaag gttcattcgc atccccccta ctcaatttct aaaaggtcat cttcttcatt
    10981 gacgaacatg ccttcttgga caataattct tttcacgact ccatcacttt ccgctgaaat
    11041 tgggatctcc attttcattg actctaaaat gaccacatct tggcctgctt ttacctcttc
    11101 cccttctgaa acgacgattt tccaaactgt tcctgccata cttgccttta tttttgtcat
    11161 ttctatcccc tccaaataat aagaactacg cgattgcctg gcttttgcgt gtcgtgaata
    11221 gttctccgcc ggcatctttg catgaatcta gcgtataaag gaaaacaggg agaaggctcc
    11281 cgtttatatt tttataatgg aatccttctc ttacttactc ttgatttctt gaatttttgg
    11341 caaataatag ttttctacaa aactcgtagt tggatatcct tttaaaaaca gttcatggct
    11401 tactgtttca atcaacatag gtatatttgt tttaatccct cctactttgt aatgatggag
    11461 agcgtccagc aagcgcttac aagcctcgtt tcggtcttta ccccaagcaa ttagttttgc
    11521 tatcatcgga tcatagaatg gtgtaaccac agttcccgct tcaatggcgc attcatgcct
    11581 gatacccggt ccttgtggta attgcaaacc cgttatttta cccggtgttg ggaaaaatgt
    11641 ttttggatcc tctgcataaa ttcttacttc aatggcatgc ccttttctct caatatcttc
    11701 tcgttgaaat gaaagagact ctcctgctgc gatttttatc tgctcagcaa ctaaatctaa
    11761 tcctaaaatt tcttctgtta ccggatgttc aacttgcaat cttgtattta cctctaaaaa
    11821 atagaagttt tgctttgaat caactaaaaa ttcaattgtg ccggcatttg tataaccaat
    11881 atattttgca gcacggacag cagcttcttg catttttgcc cttgttgctt ccgagataaa
    11941 tggtgatggt gcttcttcca ctactttttg gttacgcctt tgaattgaac attccctttc
    12001 aaatagtggg acaacatttc cataggaatc tgcaattatt tgaatttcca catggtgagg
    12061 atcttcaata agtttttcta tatacattgt gccgtcgccg aaaaatgatt ctgcccgctt
    12121 cttattccct tcgtaagcct ttacaagttg atccgaatta tcaatccgct gcatgccaat
    12181 tccgccaccc ccggcagatg cttttaacat gattggataa ccgatttttt cagcagcttg
    12241 acatgccgct tccgtatttt caagggcaat atccatccct tcaataatgg gaataccagc
    12301 ttctttcatt tttttccgag cttctaattt actccccatt gaagcaatta cttccggtga
    12361 aggtccgata aaagtgagtc cggcatctaa acaactttga gcaaacgttg cattctccga
    12421 cagtagcccg taacccggat gaatcgcctc tgcatgagat tccttggcaa tttcaataat
    12481 tttttcaata tttaaatagc tttgggcaac tggaggtttt ccgactaagt atgcttcatc
    12541 tgcctccttg acatatagcg actgagcatc ggcctctgaa tagatggcaa cggtttgaat
    12601 atttaatttt cggcacgtgc aaataattcg ccgtgcaatt tcaccacggt tggcaattaa
    12661 gattttttta aacaatgacg actccctcct tatcacttat tttatgaaac ggttcacttg
    12721 ttctctcaat ctaaactttt gaatttttcc ggaagctgtc attgggtagc tgtctgtaaa
    12781 aataatgtac tttggaattt tattgcgggc tattttattt ctacagtaat tttttatttc
    12841 ttcttctgat gctgattctc cttcacgtaa aataataaaa gcggctacct cttcaccata
    12901 cttgtcatca ggcacaccaa cgacttgcac atcgagaatt tttggatgtg tatataaaaa
    12961 ctcttcaatt tcacgcggat atatgttttc accaccgcga ataatcatat ctttcaagcg
    13021 accagtaata cggacgtaac cgttttcatc catcgttgct aaatcacccg tatgtaacca
    13081 atgctctgca tcaataactt ccttggttgc ttcgggattg ttataatatc ctttcattac
    13141 gtggtaaccg cgtgtgcaaa gttccccttg ggcaccgggc ggtacttcgg tatctgttcc
    13201 cggttcaaca atttttactt caacatttgg taatgcgcgg ccgactgttt caacccgtaa
    13261 ttccaaaggg tcatccgtac gcgtttgcgt gatcaccggt gaagattccg tttggccgta
    13321 acaaatggta atgtcgttca ttcccatttt ctgaataacg gccttcatca cttcaaccgg
    13381 acagttggaa ccggccatta cccctgttcg taacgatgaa agatcaaaat cgtcaaaatt
    13441 aggtaaattt aactcactga taaacattgt tggcacaccg tgaagtgctg tacatttctc
    13501 tttttctacc gttcttaaca cttcttcagg attaaattct tgtacaggta ccatcgttcc
    13561 tccacaggtt gttatggcca gtgtaccaat cacacaaccg aaacaatgga agaaaggtac
    13621 cggaatgcat aagcggtcat cctttgttaa tttcatacat tcggcgatgt tcactgcatt
    13681 gttaattaag ttatagtggg ttaacatgac cccttttgga aaacctgttg tccctgatgt
    13741 atattgaata ttaatgacat catcatagtg taatgttgct tttctttccg ccaattgttc
    13801 gtccgtaatc tgttctgcag cattgaggat gtcggaccag ttaaaggttc catcataacg
    13861 gttttcgcct aaaacaatga cattttttag ctttggtaac cgtttggatt gcaattgacc
    13921 aggctcagat gtttttaact cgggacatat ttcataaaca gtatcaataa agcgatgatc
    13981 acgatattgt tcaatgagaa tcagtgttgt cgaatccgac tgttttaata aatattccag
    14041 ctcacgggct ctataattcg tgtttacagt tacgagaggc gcacccattt tccctgttgc
    14101 aaattggaga cttacccact cgggaacgtt tgttgtccat acagccagat ggtcgccttt
    14161 ttcaataccg agggccatca agccttttgc cactttgtct gagagattat caagttgctg
    14221 ataagttaag cgcaaatcac gatcagtata aacaagcgct tcttggtttg gatgttgatt
    14281 cgctttttct tcaatcaatt ggccgattgt tgaaaaaatc agatctgcca ttgtatcccc
    14341 cctaatatac ttttcattcg tctactaaca tgctattgtt cttgtcggta acttcttctg
    14401 cttgagctac taaaatactt tttttactaa catctaaagg tcgccggtaa cttcttcttt
    14461 tcgggccacc attatcttgt tcgtttttct actaacatcc aattaatctg gaaataacca
    14521 ctctttgaat ctctgatgtt ccttctccaa tttccattaa cttaatgtca cgtaaatgtc
    14581 tttccacatc gtattcagcc atgtacccgt agccgccatg gatttgaatc gcttggttac
    14641 aaactctaaa acccatttcg gaagcaaata attttgcata tgccgcttct ttgctaaatg
    14701 gtttgttgtt atccttgagc cacgctgctt tgtacaacat atttctcgct aattcaattt
    14761 ccatagccat atcagcaagt ttaaattgaa tggcttggaa ctttgaaatt gaacgaccaa
    14821 attggactct ttcctttgcg tatgcaagcg ctttctcaaa ggctgcttga gcaataccga
    14881 ctgataaggc agctattgaa attcgtccgc catccaatgt atttaaaaat tgactaaatc
    14941 ctctttgcgg gtctccaagt acattttctt tcggtacacg aacattttct aacacgattt
    15001 gagaggtgtt tgatgcccga acacccattt tttgataatc agatgtaatc gccataccgg
    15061 gagcatctgt cggtacaata agtgcagtta taatcttctt cccatcttcc ctttcaccgg
    15121 ttaccgcagt aataattact tgccgagcat aacttgcatt ggtaatccaa catttttctc
    15181 cgttaatcac atattcatcc ccatcaagaa cggcttttgt tctcgtcccg ccggcatcag
    15241 aaccggcatt aggttccgtt aacccgaatg atcctaatgc ttttccttgc gccataggta
    15301 ccagccattc ttgtttttgc tcctctgtcc caaagttata aatgggggat gcacctaagc
    15361 taacggccgc cgcataactt aatcctgtac ctccgcaagc tttaccgatc tcttcaacgg
    15421 caattacata agaaatggta tccccaccgg aacccccata tttttccgga aaaggaatcc
    15481 ccattaaacc caatttaccc attttctgaa acgtgtcgag tctgaaggaa tgtgtttcat
    15541 ccagttctct cgcatatggt tttacttcct tttccgcgaa gtctcttacc atatctcgaa
    15601 tcattagctg ttctttcgtt aattcaaaat tcattctctc ccaacccctt tttctgtgat
    15661 cgaccaggcg gtattcttaa agaaaagcaa ttgtatagac cgaccagtcg gtttgttcaa
    15721 cagttataga caaaaaaata tttatttttc gctcacaatt tccctctttc ctaataattg
    15781 gttttgttca tttgcttctg taagaccttt ttctgtggct aaagaatgta cgatgagatc
    15841 tctgaaaaca tcgccaattt cctctattga taacggacca tcacgtttat accatttata
    15901 cgaccagttt atcatcccga taatggacat tgttgcaata ctggcaggca cttcttttcg
    15961 aaagtctcct ctttcttgcc cttcttttat caacctttcg atgagtttcc ggtattgatc
    16021 acgtttttcg tttatcactt ctttgtacgc agcttgtaaa taggcacttt cttgatagaa
    16081 aaccgtgata taaggattat acacatcaaa tacttttata aaggaatgta acatgccgca
    16141 taatcttaga ataggtgttt catattcatc gtatgtttcc tgtgcttttt ttatgacgta
    16201 cgatataaat acatcatgaa tttcatataa cagttcatcc tttgatttaa agtaatgata
    16261 aaatccccct tttgaagtat tggccttttc cactatttgt tcaactgtta caccatgata
    16321 tccatttttt tgaaacagtt ctagtgagct ttccagtatg cgctgcttca aagccttttt
    16381 ttccatagtt tgtttacctt tcttttaaag acaaataagt tatactgaca tttttcacag
    16441 atttaccggt aaaccttttt acacatgatg tatgaagctt ctactttgac catgtttatt
    16501 ttcccggcat tgcattattg gattaaaatt atgcatattc actctgtact ttgcttttta
    16561 atcagcccct ttttcctata cttaaggcaa tcttaccgaa aattttttta ttagtgaaat
    16621 atctattttg aatattattc attcaatttt cgaataaatc cgtatttatt atttaaaata
    16681 ttttttgcca agaccaaatt tctgtttgaa tgacggttaa taattctttt aatgcataag
    16741 attgataact gtctttgagg gtgacaattc ctaattgcca cattaattga tttgtttcaa
    16801 acgggataat ttttacgttt ttatttgttt gttttgcata gattgctttt ggtaaaatcg
    16861 ttattcctaa gtttaatgct attaattcaa aaattaaatc ccactgtgaa cttttataag
    16921 cgatttgtgg ttggaatcct tcgctttgac atgcacgaat gacaaaatca tgcagggcaa
    16981 actcggctgt aaatgtaata aactgctcat tttttaattc cggaagagtc acagctgaac
    17041 ggctcgctaa tgggtgttct gcatttacat agactacaaa ttcattttca aaaaaaggca
    17101 aaatggtaaa ttgttcgttt tcaaccggta atacaacaat tgctaaatca acttccccgg
    17161 atagtacaag ttctccgatt aactttgccc ctttctcaac cagttccagc gtgatgttag
    17221 gatatttttc atggaattta cgggcaattt cagggaaaaa taatgtgcct attaaaggcg
    17281 ggatgccaaa tttgatcttc ccagacttta cgtttcttac atcttgaatg gagcgttcca
    17341 attctaacac agaatgtaaa attttttggg catgttcgta tacgactccc ccgatatcag
    17401 taagttggag ttgtctcgtt gttcgacaaa gaagatcagc tttcaaggat gcctccagtt
    17461 tttgaatact tttacttaat gttggctggg aaatgtaaag ggcctctgca gctctcgtaa
    17521 aattcccata ttgaacaacc gcaacgaatg cctgtaaatc cctaagttcc attccgttac
    17581 cccctcatac aagtaagcga acaagtttta taattggcag aaagatgtcc tttcagcttg
    17641 tgagacgtgc cttttccccg gccgacccct ttgattcata aacaacgcat gtcaactcat
    17701 ggcgattgcc cggccggcgc tcgactggta aatgtccatc aaccggtgat tcatacacaa
    17761 ggcaagaatt cccacaaacg cccccgcttc aaccgacaat ccataaagct ttcattttag
    17821 tgttaattac aaataaaacg aataaagcaa tgctaaccga aagaatagtg gaccaattcc
    17881 cctttggcaa cagcgaatca atgaaccatt gaacagctaa agggaaggca agctcgagaa
    17941 tggcaacaac aaccgcacta ctgaagtcaa tcaaaaataa ttttttatgg ggtttatagt
    18001 atgatagaaa acgacgaatc atgtttttct ccttttttta tgcttacgtt tttattctta
    18061 ttttatcgta taatacgatc attgactatt cctgtactct ccttctatat gttagaatga
    18121 atgagtaagc gtaaataagg aaaatgttgg atgaagtgag gttctactcc aatgattaat
    18181 attcttgtta cattaaacgc aaattatctt caccctttga aagttttact gaagtcatta
    18241 tttcatcata accccaaaga aaagttctct atctatttga tgcattctaa tctcaaccaa
    18301 tatgatctgg atggattaca tcagtttatt accgaacacc aacacctgtt ctatccaatt
    18361 tttattgatc gggattattt taaagaggca cccgtgttcc gccattactc aacagaaatg
    18421 tactatcgat tagcagccca tgaatttctt cctaaaacta ttgaccgggt tctatactta
    18481 gaccctgata ttgtcaccat caatccgatt ggttcttttt atcggactaa ttttgaaaac
    18541 aatctattta ttgcgtctga gcatgagttt ccgacaaaaa tagttcaacc aatcaataaa
    18601 attcgtttaa aaacgccttt aacaaaagga tacttcaata ccggggtact attaatgaat
    18661 gtcgccttaa tgcgcgatct tgttcacttg gatgaaatat atcagtatat tgaaaagaac
    18721 aaatttaaat tagttttacc ggatcaagat gttttaaatg ctctctattg ggataaaatt
    18781 aagcccgttg acagttatcg atataattat gatgctcgct actttgagtt tgcaaagttt
    18841 taccaatccg ataaaaataa tcttgaatgg attaaaaaac atacattatt tatccattac
    18901 tgcggcaagg ataaaccttg gcatgatgat tataagggaa aattgggcgt attttatcaa
    18961 aaatttgaac aaatgatata ataaggatta caataagatg gaacttccat caggggaact
    19021 tatcttcctc ctttatattt ttgttttccc ttagacgaca tgaccgtttg tgcggggcaa
    19081 ttaattgtac ataatatgac ttatattacc tgtttaggag atgaaaaaaa ttgaaagatg
    19141 aattgattaa acgctttacc acttatgtca agattgacac acaatcaaat gaagatagcc
    19201 aaacttgtcc atccacaccg ggacaatggg atttgttgaa ccttttggta gatgaattaa
    19261 aggaaattgg catggaagaa gtaaccatcg atgaaaatgg gtatgtgttt gcaactcttc
    19321 cagccaatac gaataagcag gttccgacaa tcggtttctt agcacatgtc gatacggcga
    19381 cagattttac cggaaaaaac gtcaaaccgc aaattgtcga aaattatgat ggtggagatg
    19441 tgattttaaa caaagagcta ggaattgttt tatcaccgga agccttccct tctttaaaaa
    19501 attacaaagg gcaaacctta atcacaaccg atggaacgac cttacttgga gcggatgata
    19561 aggcaggcgt cgctgaaatt atgacggcca tgaattacct cattcaacat ccggaaatta
    19621 aacacgggaa aattcgggtt gcttttacac ctgatgagga gattggacgc gggccgcata
    19681 aatttgatgt taaccgtttt ggtgcaaagt atgcttatac aatggacggc gggccacttg
    19741 gggaattaca atatgaaagt ttcaatgcag ccgctgctaa aattacgata aaaggaaaca
    19801 acattcaccc gggttctgcc aaaggaaaaa tggtgaactc aataaagatc ggtatggagc
    19861 taaatcaaca attaccggtt agagaagccc ccgagtatac ggaaggatat gaaggatttt
    19921 accatctgct ttctttccat ggcgatgttg aaaaaactga gctttactat atcatacgtg
    19981 atcatgatcg gcaaaagttt gaagcaaaaa aagagaattt agtaaaaatc gttgaccaat
    20041 tgcgccaaaa atatggagaa gacacgattg gtttaaagtt agaagatcaa tactacaata
    20101 tgcgggaaaa aattgagccg gttaaagaag tttttgagaa cgccaaagaa gcgatggaga
    20161 gattggatat tacccctgtc attgaaccga tccgtggcgg tacggatggc tcccaattat
    20221 cttatatggg tttgccgaca ccgaatattt ttgccggtgg agaaaatatg cacgggaaat
    20281 atgaatttgt ctcagtagaa acaatgatga aagcaactga agtgataatt gaaattgcga
    20341 aaatttttga agaaaaggca aaataacttg cttgtataaa acggtgagga aaaaaacatc
    20401 ttcatctgct cgtattgaaa caatagtgga gaaaactcgg taattgccga gttttctctt
    20461 tatatcaacg tttcttcgtt tttttttgcg attatgcgaa tgcttcacct agatcgatag
    20521 aacctgaata gattttattc gtttatttat cgcgataacc ggtattagcc cggaacttca
    20581 cttctgcata acgaacgaaa tcagtttttc ctgataacac cgtccccaaa tatccgccca
    20641 aaaatccaag cggaacagaa ataatggccg gattggttag cgggaagatt gggttgccaa
    20701 caaaaatagc tgctccttca gtcggtgaaa atacacttgg actgatactt actaatacta
    20761 atgctgaaat gagacccgat aacatagcgg aaattgcccc cgctgtatta aaccgcttcc
    20821 aaaaaattgt ataaacgata accggcaaat tggcacttcc tgcaatacaa aaagcaagtg
    20881 acacaaggaa ggcaacattc atattttgtg aaaataatgc caataaaatg gagagcactg
    20941 ctacacctaa tgaagcatat tttgctgcga gaacttgttg tctttctgtt atcttaccct
    21001 ttttaataat ttgtccataa atatcatgag caaatgccga tgcaccactt aatacaagac
    21061 cggatacaac ggctaaaatg gttgcaaagg caactgctga tacaaaggac attaaaaagt
    21121 ctccgcctaa tacttgagca agtaatggag ctgccatatt ccccgcttcg tttgcttcaa
    21181 cgattttttc tgaaccgaca aaagccgctg ctccaaatcc caagaaaacc gttaaaatat
    21241 agaagattcc aacaatccat gttgcccaca tcactgaact gcgtgccgtt tgtgcatctt
    21301 taaccgtaaa gaaacgcatt aatatatgcg gaagtcctgc cgtgcctaat acgagcgccg
    21361 tcattaatga aattgtatcg agtggatttt tatattttac acccggattt aagaagtcct
    21421 ctccaagcgg tgttgcagtt ttcattttgg taaacatcgt agctatatta aaattgaatt
    21481 tagacaagac aataaaggaa ataacgacgg tagctgccat caacagaaca gccttgataa
    21541 tttgtaccca actggttgct gtcattccac caaataatac ataaatggtc atcataacac
    21601 caacgattaa tacagccaac cagtaatcaa tattgaataa taattgaata agtgcgcctg
    21661 caccgaccaa ctgagcaatc atataaaata tgacaatggt aatcgtactt aatgcagcaa
    21721 ccccgcgaac tttttttgca tcgaatcgtg cattaatcat atccgctaac gtatattttc
    21781 ctagattccg aagcggttca gcaacaataa ataaaacaac gagatatgca acgagataac
    21841 cgatactgaa gaagaaacca tcaaaccctg ttaaagcaat ggatccggca atcccaagaa
    21901 aggatgctgc cgataaatag tcaccggcta tagccaaacc attttgccat cccgttagac
    21961 ctccgcctgc cgtataaaat tcattggccg ttcttgtgcg tttagcagca aaatacgtta
    22021 tgattagcgt actagcgacg atcagtaaaa ataatataac aactgtcgta ttcatttact
    22081 ctcccccctt cttaacgaat tcttctgtaa catcggctgc taatttgtca aactttgatg
    22141 attttttcat atatatagta actaatgtcc aagtcattat gaactgagca aacgcaaaga
    22201 tccacgccca attgatgtcg ccaaatgccg gttgatgtag caattttgta taagaagtca
    22261 taatcggtaa ggcaaagtaa aataacagga aaaacacagt acacgggaca agaaattttt
    22321 tcttttgatc cattaattcc ttaaattttc ccgtctcaat gattctttca aactttgttt
    22381 tttttacttc cactttttgc tcggcatgat tcataaatga ttcctcctca gtacattttt
    22441 aagcgtttac attttgaaaa ttaagatact ttaagaaata attcttcctg tttcctaagg
    22501 tttattacac caccatttct aactaaaatt cttatatttt aaaatataca ttttttaatt
    22561 aaaatgggca acatattttt tatcttttta aaatttttct aaaataatat tgctttttta
    22621 tgtttggacc gtctttttgg cttactacat tttaccaaaa ataatattct aaattgaatt
    22681 gaattgaagg ttgctttttt catatataat aggggagttt tttataaaaa acaggggaaa
    22741 tctttgccca gtaccataaa taaatcattg aaaaagggac ttcttatgga taaagtgatg
    22801 tgagaaaata atttattgac tttcttttct tttcctgcca taatattttt gacaagtaaa
    22861 tgagtacctt taaattcagt cctgtgaggc tggcaaggtt ggcggaatac aacgttatac
    22921 tgtttctgta tccttttgtg ttggatggac ggatatagca ccttgccctt gtacaggcaa
    22981 ggtgcttttt tatatataaa aattttttcg aatcgtattt aagaaggaga gaatgatgat
    23041 ggaaaaaaat gtcatccaag ttcatgaaaa attacccttt tgggaaagtc tcccactaag
    23101 tttgcaacat ttatttgcaa tgtttgggtc aactgtttta gtccctgtgt tattcggcgt
    23161 cgatcccggg acaattttat taatgaacgg aattggtaca ctcatttaca tctttattac
    23221 aaaaggaaaa attcccgcat accttggatc aagttttgcc tttatttcac cggttttcgt
    23281 tgtgttgggc cgctattccg gtttggaagg gtatagttat gctcttggtg gattttttgc
    23341 tgttggggtc attctggtca tcattggttt aatcattaag gctgtcggta ccggatggct
    23401 ggatctcatt tttcccccgg ctgcaatggg cgctattgtt gccgttatcg ggcttgaatt
    23461 aataccaact gctgcccaaa tggccggatt tattgcgccg gcagatgcaa ccacagactg
    23521 ggccatggat ccaaagaccg tgactgtatc gcttttgact ttggccatta ctatcgtttg
    23581 ctgggtaaca ttacgcggct ttttgaaaat tatcccgata ttaattggga ttatcagtgg
    23641 gtatatcatc gctttctttg ccggtcttgt tgactttaca acggtaaaag aagcatcatt
    23701 cattgcctta ccaaccttct actctattaa atttaactgg tctgatattt tggcaattat
    23761 tccggccgct cttgtcctag ttccggagca tatcgggcat acaatggtta ccggaaacat
    23821 tgtcggaaaa gatttaacaa aggaccccgg gttggaccgc tcatttttag ggaacgggat
    23881 ttcaacaatt ctgtccagtt tggttggctc aacacccaat acaacttatg gggaaaacat
    23941 tggtgtcttg gccataacaa aagtgtattc aacatggatc attggcggag cagcagtcat
    24001 tgccattttc ctttccttct ttggtaaatt tgcagcatta atttcttcta ttccaacggc
    24061 cgtcatgggc ggaatttcct tgttgctgtt cggaatgatt gctgtgagcg gtctccgtac
    24121 acttgtggaa gcaaaagttg actatgataa atcacgaaac ttaatcttaa cttgtgttgt
    24181 tttagttgtc ggcctaagcg gcgctacaat tcaactcggc tcggtaccgc taaaaggtat
    24241 gggcttagcc accattgttg ccattattct gagcttattc ttcaaactcc ttgatgtttt
    24301 gaaattatcg aatgaaaaat ag
//
