LOCUS       NZ_KZ679082            21044 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Streptomyces sp. CS149 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ679082
VERSION     NZ_KZ679082.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS149
  ORGANISM  Streptomyces sp. CS149
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7754255)
  AUTHORS   Malmierca,M.G., Perez-Victoria,I., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Cooperative Involvement of Glycosyltransferases in the Transfer of
            Amino Sugars during the Biosynthesis of the Macrolactam Sipanmycin
            by Streptomyces sp. Strain CS149
  JOURNAL   Appl Environ Microbiol 84 (18), e01462-18 (2018)
   PUBMED   30006405
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7754255)
  AUTHORS   Olano,C., Malmierca,M.G., Mendez,C. and Salas,J.A.
  TITLE     Characterization of the biosynthesis gene cluster for the
            macrolactam sipanmycins: involvement of four glycosyltransferases in
            the transfer of two aminosugars
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7754255)
  AUTHORS   Olano,C., Malmierca,M.G., Mendez,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAR-2018) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 556.87x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 11:43:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,915
            CDSs (total)                      :: 6,834
            Genes (coding)                    :: 6,691
            CDSs (with protein)               :: 6,691
            Genes (RNA)                       :: 81
            rRNAs                             :: 12, 7 (16S, 23S)
            complete rRNAs                    :: 12, 7 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 52 of 144
            Pseudo Genes (incomplete)         :: 108 of 144
            Pseudo Genes (internal stop)      :: 12 of 144
            Pseudo Genes (multiple problems)  :: 27 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:40:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5334803
            Orig. end                         :: 5355847
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ679082.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Professor JA Salas
            laboratory.
FEATURES             Location/Qualifiers
     region          1..21044
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="17"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21044
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21044
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11044](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11044
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    251..266
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    complement(252..263)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     misc_feature    429..438
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    488..501
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            complement(528..1496)
                     /locus_tag="C6W96_RS24695"
                     /old_locus_tag="C6W96_24665"
     CDS             complement(528..1496)
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="C6W96_RS24695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24665"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_006127486.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRRAADSDDIDLVVALGGDGTVNEVVNGLLHRGPDVDNLPKLAVVPGGSTNVFARALG
                     LPNDAVEATGAILDALENRTERTVGLGLAAGTPGTEDESVPERWFTFCAGLGFDAGVVG
                     RVEQKREGGKRSTHALYVRQVVRQFLNEAHRRHGTITLDVPGQDPVTDLALSIICNTAP
                     WTYLGNRPVYASPKASFDTALDVLGLKRLSTPAVALYGTQLLTSSPEKGPRGKHAVSRH
                     DLTDFTLHSKVPLPFQMDGDHLGLRTSVTFTGVRRALRVIV"
     misc_feature    complement(1561..1574)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.29"
                     /tool="antismash"
     gene            1662..2111
                     /locus_tag="C6W96_RS24700"
                     /old_locus_tag="C6W96_24670"
     CDS             1662..2111
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072100.1"
                     /locus_tag="C6W96_RS24700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24670"
                     /product="hypothetical protein"
                     /protein_id="WP_032763749.1"
                     /transl_table=11
                     /translation="MSTQQTPSTPSPSTAERPTRITVLAGVNALEGVALAVGGIYLLIM
                     GLLGKLESTQQAETVGITLVALGAIPLIAARGLLLLRSWSRGPALITQIMALPVAWTLL
                     RSQGALIPTGIVLAVVAVTGLVLVLNPATTQDLGIRRGPRTTPDA"
     gene            complement(2142..3071)
                     /locus_tag="C6W96_RS24705"
                     /old_locus_tag="C6W96_24675"
     CDS             complement(2142..3071)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072101.1"
                     /locus_tag="C6W96_RS24705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24675"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_010072101.1"
                     /transl_table=11
                     /translation="MRDETIRSGVVRPAGIPEQQARPHPVDGADGPEGFDVAVEQQSQA
                     ERAGQMSEHGHHDPHDRSGARALFFELRELPDGSPEKAELRNRLVRMHLPLVEHLARRF
                     RNRGEPLDDLTQVATIGLIKSVDRFDPDRGVEFSTYATPTVVGEIKRHFRDKGWAVRVP
                     RRLQELRLSLTTATAELSQQHGRSPTVHELAERLGISEEEVLEGLESANAYSTLSLDVP
                     DTDDESPAVADTLGSEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQ
                     EVGISQMHVSRLLARTLAQLRERLLVEE"
     gene            complement(3095..3508)
                     /locus_tag="C6W96_RS24710"
                     /old_locus_tag="C6W96_24680"
     CDS             complement(3095..3508)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="C6W96_RS24710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24680"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_003966375.1"
                     /transl_table=11
                     /translation="MSQIAGEPGNQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVDSTVADDRTVSISLYKQRGAGPGPA"
     misc_feature    complement(3585..3605)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.43"
                     /tool="antismash"
     gene            complement(3741..4001)
                     /locus_tag="C6W96_RS24715"
                     /old_locus_tag="C6W96_24685"
     CDS             complement(3741..4001)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="C6W96_RS24715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24685"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_003966374.1"
                     /transl_table=11
                     /translation="MSECAHVADLPRPEPVPLGETCPECLEAGTHPVQLRLCLTCGHVG
                     CCDSSPLRHATGHFRATGHPVMRSFEPGESWRWCFEDGSIV"
     gene            4036..5637
                     /locus_tag="C6W96_RS24720"
                     /old_locus_tag="C6W96_24690"
     CDS             4036..5637
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510032.1"
                     /locus_tag="C6W96_RS24720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24690"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_107413291.1"
                     /transl_table=11
                     /translation="MDALPLIALVAVCAAVAGAARRTPVPAPLVLVAVGLVAGYLPGVP
                     TYHLDAHVVLPLLLPPLLHTAALDSSYLDLRANIRPVALLSVGYTLFATVAVGWLAYRI
                     IPDLPLTAALVLGAVVAPPDAVTAAAIARRVGLPARVTTILQGESLVNDATAITAFRVA
                     LAAAVGEGMSWGAGIGEFLLAAIGGVGVGLLLMVPLHWLRTHLKEALLQNTLSLLIPFV
                     AYAAAERVHASGVLAVVVVALYLGHRSWQVDFATRLQEAAVWKMVAFILESTVFALIGL
                     QLPFVLKELGPFGVQEAIGYAAAVFLAVVVVRFVWVYPATYLPRWLSRRVREREPGTDW
                     TAPLIVGWAGMRGVVSLAVAFSIPLVTQDGEPFPARSLVLFLTFTTVIGTLVIQGLTLP
                     VLVRVLKLPHPDPQTVTLIEAQAQSEASEAAEARLRELLDDPHNSLPPPLADRLRNVLE
                     RRRNAVWERLGAADPATGESADDTYRRLSREMIEAEREVFVRLRDERRIDDEMMRTLLR
                     RLDLEEAAAYREPDNS"
     gene            complement(5613..6551)
                     /locus_tag="C6W96_RS24725"
                     /old_locus_tag="C6W96_24695"
     CDS             complement(5613..6551)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072104.1"
                     /locus_tag="C6W96_RS24725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24695"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_107413292.1"
                     /sec_met_domain="PALP (E-value: 6.5e-18, bitscore: 63.8,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPAPRPPRLDALLRPRLPSPLQEVQDEGFARHGVRLFLKRDDL
                     VHPDLPGNKWRKLALNLEAAAGRTVLTFGGAYSNHLRATAAAGRLLGFGTVGVVRGDEL
                     AHRPLNPSLARCAADGMRLHFVDRTTYRAKASPEVLEGLLSRFGDVVVVPEGGSNALAA
                     QGCTALGRELAGEVDVAAVACGTGGTLAGLAAGLDPGQRALGVAVVGGGFLAGEVARLQ
                     REAFGGPAGDWSLEERFTFGGYARTTPELDAFADGFEERHGLPVERVYVAKLLYALTAL
                     AGEGAFARGSRVAAVITGTPDAPLQELSGSR"
     gene            complement(6586..7782)
                     /locus_tag="C6W96_RS24730"
                     /old_locus_tag="C6W96_24700"
     CDS             complement(6586..7782)
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127491.1"
                     /locus_tag="C6W96_RS24730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24700"
                     /product="globin domain-containing protein"
                     /protein_id="WP_107413293.1"
                     /transl_table=11
                     /translation="MLSDRSTATVRATLPVVGAAIGDIADLFYEKLFAAHPELLRDLFN
                     RGNQASGDQRRALAGSIAAFATALVEQPGTRPDVMLDRIAHKHASLGVTPEQYEVVHTH
                     LFAAIADVLGDAVTPEVAAAWDEVYWLMAGSLIAVEERLYAQQDVLAGDVWHEWEVAAR
                     VEETEDVATFLLRPAEDTPAPGFRPGQYVSVQVELPDGARQIRQYSLSCAPGSRLRSIT
                     VKRVRGQGSPDGEVSRHLHEHIRVGDLLRVSVPYGDLVLDHLDAPLLLASAGIGCTPVL
                     SMLEYLAQEGHRGPVTVVHGDRSPADHALRTDHVRLTEKLPDAEAHFWYEVPEAGQPAN
                     RTGLVDLDGITVRPGTHAYLCGPLPFMRAVRAQLLEAGVRPADVHYEVFGPDLWLASS"
     gene            complement(7878..8324)
                     /locus_tag="C6W96_RS24735"
                     /old_locus_tag="C6W96_24705"
     CDS             complement(7878..8324)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611275.1"
                     /locus_tag="C6W96_RS24735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24705"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_107413294.1"
                     /transl_table=11
                     /translation="MRLTRFTDVALRVLMRLAVAEGTEAPTTREVAATMRVPYTHAAKV
                     VARLQHLGLLDARRGRGGGLTLTSAGRSASIGSLVRELEGPEEVVECEGETPCPLRSAC
                     RLRGALRGAQDAFYAALDPITVADLVASPTGPLLLGIGSGPPPD"
     misc_feature    8355..8371
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.59"
                     /tool="antismash"
     misc_feature    8455..8469
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.08"
                     /tool="antismash"
     misc_feature    complement(8456..8467)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.3"
                     /tool="antismash"
     gene            8502..9908
                     /locus_tag="C6W96_RS24740"
                     /old_locus_tag="C6W96_24710"
     CDS             8502..9908
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061505.1"
                     /locus_tag="C6W96_RS24740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24710"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_107413295.1"
                     /transl_table=11
                     /translation="MSVGEEVRDTQAPPQQSLGTAAARNLATTTKSAPQMQEITSRWLL
                     KMLPWVQVQGGTYRVNRRLSYSVGDGRVTFVQTGDRVAVIPAELGELPALRNFGDEEVL
                     AELARRCEQRDVAAGEVLAASGDAADRVFLLAHGKIEKVGSGLYGDETELGVLADGAYF
                     GDRSLIDGDAVWEYTARALTPCTLLTLSRADVYNLAERAESLQSHLAGLLSIPEQRTNH
                     YGEAAIDLSAGHVGEAVVPHTFVDYDAAPREYELSVAQTVLKVHSRVADLYNQPMNQTE
                     QQLRLTVEALRERQEHELINNREFGLLNNCDYGQRIQPHDGVPSPDDMDELLSRRRGSK
                     LFLAHPKAIAAFGRECNRRGLVPESVDIGGHHVPAWRGVPIFPSNKIPVTDARTTSIIC
                     MRTGEAEQGVIGLQQTGIPDEIEPSLSVRFMGIDEQAIISYLVTAYYSAAILVPDALGV
                     LENVEVSRWR"
     gene            10001..11044
                     /locus_tag="C6W96_RS24745"
                     /old_locus_tag="C6W96_24715"
     CDS             10001..11044
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959111.1"
                     /locus_tag="C6W96_RS24745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24715"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_093812321.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.2e-60, bitscore:
                     202.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTDAATEGHEAAALLERTRAVVDPHLRSAVESLPGAIRRIAMY
                     HFGWQNADGTPASGQAGKAIRPALVLAAARALGGDPERAIRAAVAVELAHNFTLLHDDV
                     IDEDTTRRHRPTAWAVFGVPDAIITGDAMLALAQRLLAEDTHPAAAPAAARLSTCVIEL
                     CAGQQADCAFEERGPDEVTLDECLTMATAKTGALLGCACALGALYAGAEDRAVRAMDGF
                     GREAGLSFQLIDDLIGIWGDPDRTGKPVGADLSAHKKSLPVVAALTSGTPAAAELAALY
                     RGPMNTAAEVSRAADAVDRAGGRDWAQVCAADRMARAVHHLSRAVPDPSAAGDLLALAE
                     FVTRRTS"
     gene            11134..11730
                     /locus_tag="C6W96_RS24750"
                     /old_locus_tag="C6W96_24720"
     CDS             11134..11730
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959110.1"
                     /locus_tag="C6W96_RS24750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24720"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_107413296.1"
                     /transl_table=11
                     /translation="MGIRIQQAEPRDRELVVSVMEEAFHDDPVSSWVFPDEAHRRAVHG
                     KFLGVFVDVALDEGRIDIAEDEAAVALWLQVPAGAPEEEDPTPALMRETADPDNERCEL
                     VGRLTGAVHPHDRAHAYLLMIGVRPDRQGEGIGAELISAELERCDREGLPVYLEASSAR
                     SRTLYERLGFRFLGRAVDLPDGPPMYPMWREPQAG"
     gene            11761..>12192
                     /locus_tag="C6W96_RS24755"
                     /old_locus_tag="C6W96_24725"
                     /pseudo=""
     CDS             11761..>12192
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959109.1"
                     /locus_tag="C6W96_RS24755"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24725"
                     /product="DUF6304 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTDESWAGWYRDNKGSDSVVLTTDGQRIRLRIRGADFEGESFDGL
                     RPVAGVPPENGTFGLKDGALTDCVLEWDQQLPVLVAGTLRHATLSCLLSLRRAEPDFHL
                     ALHLDGAVYESARAERDFAEALAAVQRILPGGISLQACVA"
     gene            12379..13347
                     /locus_tag="C6W96_RS24760"
                     /old_locus_tag="C6W96_24730"
     CDS             12379..13347
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061501.1"
                     /locus_tag="C6W96_RS24760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24730"
                     /product="DUF1648 domain-containing protein"
                     /protein_id="WP_107413298.1"
                     /transl_table=11
                     /translation="MTSKNVGRVTLAALPFVLALLIDLALYAAVADRLPDRLAVHFDAG
                     GSANGYTSSRSYLLYTLASLLVLGALWVFIAVKGRLRGRAHRWLIGGGFAVAAFLGYLL
                     IAVLFVNVDVPEGGSAGGFPLEHIAVALAAATLAGALGVLLSRLVPLPEDPRDPDPATR
                     ERLVLADGEVAAWGRGIGAWWAPVAVLVLLAAGVTVGREQSWFIGVPLILFALVTGTFC
                     RPHVTVDRRGLTVSGLLPRPRVRVPLERMEGADSRPVNALAEYGGWGYRIRPERSGVIT
                     RSGEAIVVSLTSGREFAVTVGDSATGAALLNTLLDRQRAGR"
     gene            13350..13706
                     /locus_tag="C6W96_RS24765"
                     /old_locus_tag="C6W96_24735"
     CDS             13350..13706
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458277.1"
                     /locus_tag="C6W96_RS24765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24735"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_006127498.1"
                     /transl_table=11
                     /translation="MLFRVDPTSTVPLGDQIAASVRRAVAEGAVAPGERLPAARALAES
                     LGVNVHTVLRGYQRLREEGLIELRRGRGAAITAGASPQRARLLERVREAVADARDLGMT
                     EDELLTLVRNELDA"
     gene            complement(13871..14527)
                     /gene="snpA"
                     /locus_tag="C6W96_RS24770"
                     /old_locus_tag="C6W96_24740"
     CDS             complement(13871..14527)
                     /EC_number="3.4.24.77"
                     /codon_start=1
                     /gene="snpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127499.1"
                     /locus_tag="C6W96_RS24770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24740"
                     /product="snapalysin"
                     /protein_id="WP_030716572.1"
                     /transl_table=11
                     /translation="MRHLKNAVATAAAGLGLVAALGTAPVAVAAPAPAAPSASSTIAAY
                     NGSGENAAANRAFLDAVMKSVAEKRAANPGIKAVTVTYDASGAPSFRSQIANSTQIWNS
                     SVSNVQLQEGSGADFTYREGNDPRGSYASTDGHGRGYIFLDYAQNQQYDSTRVTTHETG
                     HVLGLPDNYSGPCSELMSGGGPGPSCTNAQPDANERARVNQLWQNGLASLARSAS"
     gene            14844..15797
                     /locus_tag="C6W96_RS24775"
                     /old_locus_tag="C6W96_24745"
     CDS             14844..15797
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127501.1"
                     /locus_tag="C6W96_RS24775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24745"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_107413299.1"
                     /transl_table=11
                     /translation="MELEVRHLKALCAIADAGSLHQAARRLGVSQPSLTTQLQRIENVL
                     GAELFLRERTGCRPTSLGRAVLSRARPLVDGMSDLVAAALAEAEAARPRGSRLRIGSTA
                     SRVIGGWLRRLRIALPGTDISLRVDVSAHELLRSVAAGRLDVAFVHEVEGCPLTLPEGL
                     EQRVLVDREPQFISLSRDHPAARRRVVELGDLAGDPWMVDPTVDGEWDGVRRVLGAAGL
                     NPPVLHGDYLTAASLVVLGEAVAPCQPTSGPRDDMVIRPLLGDPLAVRLLLVSRPGTDI
                     EVVYAQLEDAYRDAARRASGYHEWLLRHRSPLARTS"
     misc_feature    15884..15898
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            15898..16896
                     /locus_tag="C6W96_RS24780"
                     /old_locus_tag="C6W96_24750"
     CDS             15898..16896
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458285.1"
                     /locus_tag="C6W96_RS24780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24750"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_234389385.1"
                     /transl_table=11
                     /translation="MRLLMLGGTEFVGRAVTDAALERGWDVTVFHRGHHAPPPGVSALT
                     GDRTTGERGLAALAESGRDWDLVVDTWSGAPAAVRDAARLLSGRAGHFSYVSSRSVYAH
                     PAAPGLDEEGPLVTGASPDDGGDVPYDRAKRGGELAALEAFGDRAMLARAGLIIGPGEN
                     IGRLPWWLSRIDRGGPVIAPGRPDVELQYIDARDLAVWILDAAADGLHGAYNTVSRPGH
                     ATMGELLEACVRTTGSDAELRWTDPEVLLAAGAEPWSDLPIWLPPGELYDTLHRGDHTK
                     AYAAGLRCRPVEETVADTWTWLRALGGTAPRRPDRPAVGLDPGLEAKLLAL"
     gene            17053..>18127
                     /locus_tag="C6W96_RS24785"
                     /old_locus_tag="C6W96_24755"
     CDS             17053..>18127
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019546145.1"
                     /locus_tag="C6W96_RS24785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24755"
                     /product="choice-of-anchor A family protein"
                     /protein_id="WP_325048195.1"
                     /transl_table=11
                     /translation="MEQKARRRGNAIRAAVTVATAAAMVGVLAPAAGADPLPGGLGPCL
                     GSSCPPSWNDPNNLPVVGFDSNINVFVGGDFLVREAAAEAEGKVVTLGEFDMNKRAGVS
                     QVYNVGIAGVGSRVPPPDGSDYLTTGGDVTIADGQRLLAEEGEHSGRVAYAGELTGTVN
                     PTTAPRFDEDAAAPYTQLRPQLTEASQCYAYDGDEHREATGTWQQVGDVMTFTGDGTSA
                     IQIFDVDVDLESEAGGNTGFVFNGIPAGATVLVNVYGSTRSVATFMGSFPNEGLRENLL
                     WNFPDATDLSLTGPAQFEGSVLVGQPTSSTVLSMSGTNGRFYTAGSLTHTSQGQSGGQE
                     IHAYPFDGDLPSCTPDPT"
     assembly_gap    18128..18152
                     /estimated_length=25
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <18153..18418
                     /locus_tag="C6W96_RS35400"
                     /pseudo=""
     CDS             <18157..18418
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127503.1"
                     /locus_tag="C6W96_RS35400"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="peptidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="TPTPTEPTPTPTDPTPTPTDPTPTPTEPTPTPTHHTPRPTHSPSH
                     PGELPDTGSRGGEWIIGSIAAALVAAGGTVLVATRRARRRTF"
     gene            18452..18811
                     /locus_tag="C6W96_RS24790"
                     /old_locus_tag="C6W96_24765"
     CDS             18452..18811
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959102.1"
                     /locus_tag="C6W96_RS24790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24765"
                     /product="DUF952 domain-containing protein"
                     /protein_id="WP_107413301.1"
                     /transl_table=11
                     /translation="MTEPLLHLAEAPLWEAARGTGTYEMSTRGRTLQEEGFIHLSLPRQ
                     LPGVARMLYGDDDRDLVVLVVDPGRLADPVRYEAMKPGGEEFPHLYGPLPVGAVVEVRR
                     LADWYHDRREEDEPQ"
     gene            18808..19689
                     /locus_tag="C6W96_RS24795"
                     /old_locus_tag="C6W96_24770"
     CDS             18808..19689
                     /EC_number="1.6.5.2"
                     /GO_function="GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611287.1"
                     /locus_tag="C6W96_RS24795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24770"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_107413302.1"
                     /transl_table=11
                     /translation="MIGPLTAVTGASGAVGGRVARRLARTGVPVRLLGRDPARLPDVPG
                     ADRAPAAPYGDGEAMRRALDGAHTLFLVSAHESPYRVREHTTAIDAAVAVGVERIVYVS
                     FQGAAPDATFTFARDHWDTEAHIRTAEIRHTFLRDNWYLAGLPAMTGTDGVLRGPGGDG
                     RVAAVAHEDIADAAAAVLLDEGTDHDGRVYDLTGPEAFTLAEAADELSRVTGRPVVYVP
                     ETREEAYASRAGYGAEDWEVAGWVTSYEAIANGELAAVSDAVPTLTGRPAQSFAQFLVE
                     NPDSYRHLLPGG"
     gene            complement(19706..20893)
                     /locus_tag="C6W96_RS24800"
                     /old_locus_tag="C6W96_24775"
     CDS             complement(19706..20893)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379079.1"
                     /locus_tag="C6W96_RS24800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24775"
                     /product="DUF1266 domain-containing protein"
                     /protein_id="WP_107415055.1"
                     /transl_table=11
                     /translation="MNPIHPIHPSAPPAAPAPWVPPSETEQLLHEAALRGDVRGQLAAL
                     AGTELYIPAPRAEVDADPDTVMWRRHVDPAGFVCRPLLTRGMLPAWHPDWVFRGVSLRW
                     IAEFGWSDPQVWLGVNVGTPGQLLLPTAPPDLALWQRAYAENDRASGNRLVALRHGALH
                     GPLAYGLACGAHLAIGNAVPWNEIGTVYREYVDEREQLRDSWGITDHEGWRRQLDFLLD
                     AANSPPEPDFALRAREQLTAAIGELPSADLWRETAAGHAQDLGADASTVKGIADLVRRI
                     MRYEARFRADGLLPPDGRVRTTVAYDYGRAVNLARWGLSARFCGPADAEAAIVYAGALS
                     KSAYRSWEEFSAGYALGRVLRFDDEEYGPFYEQNVLAHRLLTESEGSPWRHIPWR"
ORIGIN
        1 gcggcgctcg tcctcgctga ggccacccca gacgccggag tcctggccgg actcgagcgc
       61 ccactgcagg cactgctcca tgacggggca gcggcggcag acagccttgg cttcctcgat
      121 ctgcagcagc gcaggaccgg tgttgccgat ggggaagaac agctcggggt cttcctcacg
      181 acaaacggcg ttgtgacgcc agtccatggc tgctacctct ccttggtatt acacgcttgt
      241 tgcttgtgaa tgtgaacgct ttcacgaatc cccccgcaga tgacgggccg acccccagat
      301 ggactgggtg tggtctgtga tggtgaggag gggttctggc tctcagtgga ggccggtgtt
      361 gcgggccgtc ccgatcgcca tgaagagatt cccaaacctc ggcgacggat acaacccctt
      421 ctggaaagtt ttttttgatt cctcggtgtc gactaggtca caggcgcact tcttgggggt
      481 gggacccagt ccaaacgttc gagttaaagg actttcggcc cttccactca cacaatcaca
      541 cgcagtgcac ggcgtacgcc tgtgaacgtc acgctcgtac gcagtcccag gtggtcaccg
      601 tccatctgga agggcagtgg gacctttgaa tgcaaggtga agtccgtgag gtcatgccgt
      661 gaaacggcgt gcttcccgcg gggccccttc tcggggctcg aagtgagcag ctgggtgccg
      721 tacagggcca ccgccggggt ggacagacgc ttcagtccga ggacgtccag cgcggtgtcg
      781 aaggaggcct tcggcgaggc gtagaccggg cgattgccca ggtaggtcca gggggcggtg
      841 ttgcagatta tggagagcgc gaggtcggtc accgggtcct ggccgggcac gtcgagcgtg
      901 atcgtcccgt gtctgcggtg ggcctcgttc aggaactgcc gcaccacctg gcggacgtag
      961 agggcgtgcg tcgaacgctt gccgccctcg cgtttctgtt cgacccggcc gacgactccg
     1021 gcgtcgaacc cgagtccggc acagaaagtg aaccagcgtt cggggacgga ctcgtcctcc
     1081 gtgcccgggg tgccggcggc caggcccaga ccaaccgtgc gttcggtccg gttctccagg
     1141 gcgtccagga tcgcgccggt cgcctccacc gcgtcgttcg gcagccccag ggcgcgcgcg
     1201 aagacgttcg tggacccacc ggggaccacg gcgagcttcg ggaggttgtc cacgtccggt
     1261 cccctgtgca gcagcccgtt cacgacctcg ttcaccgtgc cgtcgccgcc gagggcgacc
     1321 accagatcga tgtcgtcgct gtccgcggcc cgccgcccca gatcccgtgc gtgcccccgg
     1381 tactccgtgg tcaccgcctc cagcttcatc tcgctggcca gcgcgtggat gagcacgtca
     1441 cgggtgcggg cactggtggt ggtagcagct ggattgacca cgaggagtgc gcgcatgacg
     1501 gccagcctac ctaccgggcg gttcggccct gaagtcccgg ttcgctgcgc tcgggaccgg
     1561 tgacggagcg tgacgaaccg ccccggtcca ccgccgaacg ggtgcgactc ccgcgcaccc
     1621 cggcttcact tccggccgcc ggggatgcca acctgaaagg cgtgagcact cagcagacac
     1681 cgtccacgcc gtcgccctcc accgcggagc gcccgaccag gatcaccgtc ctcgccgggg
     1741 tcaacgccct cgaaggcgtg gctctcgccg tcggcgggat ctacctgctg atcatggggc
     1801 tgctggggaa gctggaaagc acgcagcagg cggagacggt cggaatcacc ctggtcgcgc
     1861 tcggcgccat cccgctgatc gccgcccgcg gactgctgct gctgcgcagc tggagccggg
     1921 ggcccgcgct gatcacccag atcatggcgc tgccggtggc ctggacgctg ctgcgctcgc
     1981 agggtgcgct gatccccacc gggatcgttc tcgcggtggt cgccgtcacc ggcctcgtgc
     2041 tcgtcctgaa cccggcgacc acccaggacc tgggcatccg tcgggggccg aggacgacac
     2101 ccgacgcctg agcctcccgg ccccgctcgt cgctcctcgg ctcactcctc gacgagcagc
     2161 cgctcgcgga gctgcgccaa ggtgcgggcc agcagccgcg agacgtgcat ctgcgagatg
     2221 ccgacctcct gggcgatctg cgactgggtc atgttcccga agaaacgcag cagcaggatc
     2281 cgcttctcgc gcggcggcag gtcctccagg agcggcttga gcgactcccg gtactccacg
     2341 ccctccagcg cctcgtcctc cgagcccagc gtgtccgcca cggccggcga ctcgtcgtcc
     2401 gtgtccggca cgtccagcga gagcgtgctg tacgcgttgg ccgactccag gccctccagc
     2461 acctcctcct cggagatgcc gagccgctcc gccagctcgt gcacggtcgg cgaccggccg
     2521 tgctgctggg agagctccgc ggtggccgtg gtcagcgaga gacgcagctc ctggagacgg
     2581 cgcggcaccc gcaccgccca gcccttgtcc cggaagtggc gcttgatctc gccgaccacc
     2641 gtgggagtgg cgtacgtcga gaactccacc ccccggtccg ggtcgaaccg gtccacggac
     2701 ttgatcagcc cgatcgtggc gacctgcgtc aggtcgtcca gcggctcgcc gcgattgcgg
     2761 aaccggcggg ccagatgctc caccagcggc agatgcatcc gcaccagccg attgcgcagc
     2821 tcggccttct ccggggaacc gtcgggcagc tcccgcagct cgaagaacag ggcccgggcc
     2881 ccgctgcggt cgtgtggatc gtggtgcccg tgctcgctca tctggcccgc ccgctctgcc
     2941 tgcgactgct gctccaccgc gacgtcgaag ccctcgggcc cgtccgctcc gtccaccgga
     3001 tgcggccggg cctgttgctc cgggatgcct gctgggcgca ccaccccgga tcggatcgtc
     3061 tcgtcccgca caggaccgtc cccgttcccg tcgctcacgc cggcccgggg cccgcgccgc
     3121 gctgtttgta gaggctgatg ctgaccgtac ggtcgtccgc gactgtggag tcgaccttgc
     3181 cggccagtgc ggagagcacc gtccaggcga aggtgtcgcg ctcgggcgcc cggccgtcgg
     3241 tggtgggcgc cgacaccgtc acttcgaggg agtcgtcgac gagtcggaag acgcagctga
     3301 ggacggagcc cggcacggcc tgctggagca ggatcgcgca ggcctcgtcg accgcgatgc
     3361 gaagatcctc gatctcgtcg agagtgaagt ccaaacgcgc tgcgagaccg gccgtggccg
     3421 ttcgcagcac cgacaggtag gcacccgcag cgggcagccg gacttctacg aagtcctgat
     3481 tcccgggctc gcctgcgatc tgggacaccc tcacctccaa ggtggcacaa actctttcga
     3541 ggttccggga agggtggccc ggagccatgc ggtccgtcga cggttcttcg gctcggcgac
     3601 gttatcggat ccatgatgcc gtgtcgtacg gaccccatac ctcgaccgtc actcatggta
     3661 agcccatgag tacggaaagt ggctaggggt ctgcggcgtc caattacgaa gaaccggcgc
     3721 cgcattgacg tacccagacg tcagacgatc gaaccgtcct cgaagcacca gcgccagctc
     3781 tcgcccggct cgaagctccg catcacgggg tgaccggtcg cccggaagtg tccggtggcg
     3841 tgccgcagcg gcgacgaatc gcagcagccg acgtgcccgc aggtcagaca gagccgcagt
     3901 tgcacggggt gggtgcccgc ctccaggcac tcgggacagg tctcgccgag cggcacgggc
     3961 tcggggcgtg gcagatccgc tacatgcgca cactcgctca tgatgggcag gttacgacgg
     4021 atcgaggacg gtgggatgga cgcgctgccg ctgatcgccc tggtcgccgt gtgtgcggcg
     4081 gtggccggcg cggcccgccg cactcccgtg cccgccccgc tcgtgctggt cgccgtaggc
     4141 ctcgtggccg gctacctgcc gggcgtcccg acgtatcacc tggacgccca tgtcgtcctc
     4201 ccgctgctgc ttccgccgtt gcttcacacg gcggccctgg acagctccta cctggacctg
     4261 cgggccaaca tccggccggt cgccctgctc tccgtgggct acaccctctt cgccaccgtc
     4321 gcggtgggct ggctggcgta ccggatcatc ccggacctgc cgctgaccgc cgcgctggtc
     4381 ctgggggcgg tcgtcgcccc gccggacgcc gtgacggccg ccgccatcgc ccgccgggtc
     4441 gggttgcccg cccgggtgac cacgatcctc cagggcgagt ccctggtgaa cgacgccacg
     4501 gcgatcaccg ccttcagggt ggcgctggcc gcggcggtgg gggaggggat gagctggggc
     4561 gccggaatcg gcgagttcct gctcgccgcg atcggcgggg tcggcgtcgg cctgctgctc
     4621 atggtgccgt tgcactggct gcgcacccac ctcaaggaag cgctcctcca gaacacgctg
     4681 tccctcctga tccccttcgt ggcgtacgcg gcggccgaac gggtgcacgc ctccggtgtc
     4741 ctcgccgtgg tcgtcgtcgc cctctatctg gggcaccgtt cctggcaggt cgacttcgcc
     4801 acccggctcc aggaagcagc cgtctggaag atggtggcgt tcatcctgga gtccacggtg
     4861 ttcgcgctga tcggcctcca gctgccgttc gtcctgaagg agctcggccc gttcggtgtc
     4921 caggaagcca tcggatacgc ggccgcggtc ttcctggccg tcgtcgtggt ccgcttcgtc
     4981 tgggtctacc cggccaccta tctgccccgg tggctctccc ggcgggtgag ggagcgggag
     5041 cccggcaccg actggaccgc gccgctcatc gtcggctggg ccgggatgcg tggggtcgtc
     5101 tcgctcgccg tcgcgttctc catcccgctg gtcacgcagg acggcgaacc gttcccggcc
     5161 cgcagcctgg tcctgttcct gaccttcacc accgtcatcg ggacgctggt gatccagggc
     5221 ctgaccctgc ccgttctcgt ccgcgtactg aagctgccgc accccgaccc gcagaccgtc
     5281 accctcatcg aggcgcaggc ccagagcgag gcgtccgagg cggcggaggc ccggctgcgg
     5341 gaactgctcg acgacccgca caacagcctg ccgccaccgc tggccgaccg gctgcgcaat
     5401 gtgctggagc gccgccgcaa cgccgtctgg gagcggctgg gcgccgccga cccggccacc
     5461 ggggaatcgg cggacgacac ctatcggcgg ctgtcgcggg agatgatcga ggccgaacgc
     5521 gaggtcttcg tccggctccg ggacgagcgg cggatcgacg acgagatgat gcgtacgctg
     5581 ctgcgccgac tggacctgga ggaagccgcc gcctaccggg agccggacaa ctcctgaagc
     5641 ggtgcgtccg gggtgccggt gatcaccgcg gccacccggc tgccccgcgc gaacgccccc
     5701 tcgccggcca gcgcggtcag cgcgtacagc agcttggcga cgtagacgcg ctccacgggc
     5761 agcccgtgcc gctcctcgaa accgtcggcg aaggcgtcca gctccggggt cgtacgggcg
     5821 tagccgccga aggtgaagcg ctcctccagt gaccagtccc cggccgggcc gccgaacgcc
     5881 tcacgctgga gccgcgccac ctccccggcc aggaaccccc cgccgaccac cgccacgccc
     5941 agcgcccgct gcccgggatc cagcccggcg gcgagcccgg ccagggtccc gccggtcccg
     6001 caggccacgg ccgccacatc gacctcaccg gccagctcgc gccccagcgc cgtacagccc
     6061 tgcgcggcca gggcgttgct gccgccctcc gggacgacca ccacgtcccc gaaccggctc
     6121 agcagcccct ccaggacctc gggggaggcc ttcgcccggt acgtcgtccg gtccacgaag
     6181 tgcagccgca tcccgtcggc cgcgcaccgg gccagcgagg ggttgagcgg ccggtgcgcc
     6241 agctcgtcgc cgcgaacgac gccgacggtc ccgaagccca gcagccgccc ggccgccgcg
     6301 gtggcccgga ggtggttgga gtacgcgccg ccgaacgtga gcacggtgcg cccggcggcg
     6361 gcctccagat tgagggcgag tttgcgccac ttgttgcccg gcagatcggg gtggaccaga
     6421 tcgtcccgct tgaggaacag ccgcaccccg tggcgggcga aaccctcgtc ctggacctcc
     6481 tgcaaggggg aggggagccg gggccgcagg agggcgtcga ggcggggcgg gcggggggcc
     6541 gggctggtca cccgctcatt gtcgcctgcc tgccgtggcg gcgtttcagg aggaggccag
     6601 ccagaggtcc gggccgaaca cctcgtagtg gacgtcggcc ggccggacac ccgcctccag
     6661 cagctgggcc cggacggccc gcatgaaggg gagcgggccg cacaggtagg cgtgcgttcc
     6721 cggccgtacg gtgatgccgt ccagatcgac gaggccggtg cggttcgccg gctgtccggc
     6781 ctccgggacc tcgtaccaga agtgcgcctc ggcgtccggg agcttctccg tcagccgtac
     6841 gtggtcggtg cgcagggcgt ggtcggccgg tgagcggtcg ccgtgcacga cggtgaccgg
     6901 gccccggtgc ccttcctgcg cgaggtactc cagcattgac agcacggggg tgcagccgat
     6961 gcccgccgag gccagcagca ggggcgcgtc caggtggtcg agcaccaagt ccccgtaggg
     7021 gaccgagacg cgcagcaggt cacccacgcg gatgtgctca tgcaggtgac gggagacctc
     7081 accgtcgggt gagccctggc cgcgcacgcg cttcacggtg atcgaccgga gccgggagcc
     7141 gggggcgcag gagaggctgt actgacgtat ctgacgggcc ccgtcaggaa gctcgacctg
     7201 tacggagacg tactggccgg gcctaaagcc gggcgcgggc gtgtcctcgg cggggcgcag
     7261 caggaacgtg gcgacgtcct cggtctcctc cacccgggcg gccacctccc actcgtgcca
     7321 gacatcgccc gccaggacgt cctgctgggc gtagaggcgc tcctcgacgg cgatcaggga
     7381 gcccgccatc agccagtaga cctcgtccca ggcggcggcg acctccgggg tgaccgcgtc
     7441 gcccaggaca tcggcgatgg ccgcgaacag atgggtgtgc accacctcgt actgctccgg
     7501 ggtcaccccg agcgaggcgt gcttgtgggc gatccggtcc agcatcacgt cgggccgggt
     7561 gcccggctgc tcgaccagcg cggtcgcgaa cgcggcgatg gacccggcca gggccctgcg
     7621 ctgatcgccg gaggcctggt tgccccggtt gaacaggtcc cgcagcagct cggggtgggc
     7681 ggcgaagagc ttctcgtaga agaggtcggc gatgtccccg atggccgcgc cgacgacggg
     7741 aagggtggcg cggacggtgg cggtggaccg gtcggagagc atgaggctcc ttattattgg
     7801 aatgctgaat gcacatttaa gggcaggggg aactcgcccc gcatgggtgt gcgcgagcgt
     7861 gcggggccgg gacggggtca gtcgggtggc gggccgctgc cgatgccgag caggagcggg
     7921 ccggtggggg aggcgacgag gtcggcgacg gtgatcgggt ccagtgcggc gtagaaggcg
     7981 tcctgggccc cgcgcagggc cccgcgcagt cggcaggcgg atcggagcgg gcaaggggtc
     8041 tcgccctcgc actcgacgac ctcctccggc ccctccagct cccgcaccag tgagccgatc
     8101 gacgcggagc ggccggccga ggtcagggtg agcccgccgc cccggccgcg ccgcgcgtcg
     8161 aggaggccga ggtgctggag gcgggcgacg accttcgcgg cgtgcgtgta cgggacccgc
     8221 atggtggccg ccacctcgcg ggtggtcggc gcttccgtgc cctcggcgac ggcgagccgc
     8281 atgaggacgc ggagtgccac gtcggtgaat ctcgtcagcc gcatgagctc aacctagata
     8341 agttgcactg aggatgcaaa ttaaaggcgc ggctcggtga cggggctcaa cgtgccccgt
     8401 ctgaaggtgg attagtcaca ctcttttgtg taatggcggg cccgcccctc ctgctgaaag
     8461 tcttttcctc gcaggtcagc ccatgatcga gaggacgtca gatgtccgtt ggtgaagagg
     8521 ttcgcgacac gcaggcgccg ccgcagcaga gtctggggac ggcagctgcg cggaacctcg
     8581 cgacgaccac caaatccgcg ccgcagatgc aggagatcac ctcgcggtgg ctgctgaaga
     8641 tgctgccgtg ggtgcaggta cagggcggta cgtaccgggt gaaccgtcgg ctcagctatt
     8701 cggtcggtga cggccgggtg accttcgtcc agaccgggga ccgggtggcc gtgatccccg
     8761 cggagctggg ggagctgccc gctctgcgca acttcgggga cgaggaggtc ctcgccgagc
     8821 tcgcccgcag gtgcgagcag cgggacgtgg ccgcggggga ggtgctcgcc gcctcggggg
     8881 acgcggcgga ccgggtcttt ctgctggcgc acggcaagat cgagaaggtc ggatccggcc
     8941 tctacgggga cgagacggag ctcggggtcc tcgccgacgg cgcgtacttc ggcgaccgga
     9001 gtctgatcga cggcgatgcc gtctgggagt acacggcccg cgcgctcacc ccgtgcacgc
     9061 tcctcaccct gagccgggcc gatgtgtaca acctcgcgga gcgcgccgaa tccctgcaga
     9121 gccacctcgc cgggctgctc tccattccgg agcagcggac caaccactac ggcgaggcgg
     9181 cgatcgacct ctccgccggc catgtcggcg aggcggtcgt cccgcacacc ttcgtcgact
     9241 acgacgcggc gccccgcgag tacgaactga gcgtcgccca gaccgtgctg aaggtccaca
     9301 gcagggtcgc cgacctctac aaccagccga tgaaccagac cgagcagcag ttgcggctca
     9361 cggtcgaggc gctgcgcgag cgccaggagc acgagctgat caacaacagg gagttcggac
     9421 ttctcaacaa ctgcgactac gggcagcgga tccagccgca cgacggggtg cccagcccgg
     9481 acgacatgga cgagctgctc tcgcgccgcc gcggatcgaa gctcttcctc gcccacccga
     9541 aggcgatcgc cgccttcggc cgtgagtgca accggcgggg actcgtcccg gagagcgtcg
     9601 acatcggcgg tcaccacgtg cccgcctggc gcggggtgcc gatcttcccg tccaacaaga
     9661 tccccgtcac cgacgcccgc accacctcca tcatctgcat gaggaccggc gaggccgagc
     9721 agggcgtcat tggcctccag cagaccggca tccccgacga gatcgaaccg agcctctcgg
     9781 tccgtttcat ggggatcgac gagcaggcga tcatctccta cctcgtgacg gcgtactact
     9841 ccgccgccat cctggtaccg gacgccctcg gagtgctgga gaacgtcgag gtcagccgct
     9901 ggcgctgatc ccgagtcacc ccgggggtcc gggcgggcag ccgccgcccg gacccccggg
     9961 tccgcaccca ccgcctcgcc ccagggagtt gaccgtgacc atgaccagta cggacgcagc
    10021 gacggaaggg cacgaggccg cggcgctcct ggagcgcacc cgcgccgtcg tcgacccgca
    10081 tctgcgatcg gccgtggagt cgttgcccgg cgccatacgc cggatcgcga tgtaccactt
    10141 cggctggcag aacgccgacg gaaccccggc ctccggccag gccggaaagg ccatcaggcc
    10201 ggccctcgtg ctggccgccg cccgcgccct gggcggcgat ccggaacgcg cgatcagggc
    10261 cgccgtcgcc gtcgaactcg cccacaactt caccctgctc cacgacgacg tcatcgacga
    10321 ggacaccacc cgcaggcacc ggcccaccgc ctgggcggtc ttcggcgtcc cggacgccat
    10381 catcaccggc gacgccatgc tcgccctcgc ccagcggctg ctggccgagg acacgcaccc
    10441 ggccgccgcg cccgccgccg cccggctctc cacctgcgtc atcgagctgt gcgcgggcca
    10501 gcaggcggac tgcgccttcg aggagcgcgg ccccgacgag gtcaccctcg acgaatgcct
    10561 caccatggcg accgccaaga ccggcgccct gctcggctgc gcctgcgcgc tcggcgccct
    10621 ttacgccggg gcggaggacc gggccgtccg cgcgatggac gggttcggcc gggaggcggg
    10681 tctctcgttc cagctcatcg acgacctgat cggcatctgg ggcgaccccg accgcaccgg
    10741 caagcccgtc ggggccgacc tctccgccca caagaagtcc ctgcccgtgg tcgccgctct
    10801 cacctcgggc accccggccg ccgccgagct cgccgcgctc taccgggggc ccatgaacac
    10861 cgccgccgag gtgagcaggg cggccgacgc ggtggaccgg gccggcgggc gggactgggc
    10921 ccaggtctgc gcggccgacc ggatggcccg ggcggtccac cacctctccc gggcggtccc
    10981 cgacccgagc gcggcgggcg acctgctggc gctggccgaa ttcgtcaccc gccggaccag
    11041 ctgacccacc tcgggtgacc ggcggcgccc tgtcaactct agtattccgg aggttggttg
    11101 aaggaaggca gcagagagag gcggcagccc gtcatgggta tacggatcca gcaggcggag
    11161 ccacgcgacc gggagctcgt cgtctcggtc atggaggagg ccttccacga cgacccggtc
    11221 agcagctggg tgttccccga cgaggcgcac cggcgcgcgg tgcacgggaa gttcctcggc
    11281 gtcttcgtcg acgtcgccct cgacgagggc cgtatcgaca tcgccgagga cgaggcggcg
    11341 gtggccctct ggcttcaggt gcccgccggg gcccccgagg aggaggaccc cacccccgcc
    11401 ctgatgcgtg agaccgccga ccccgacaac gagcgctgcg aactggtggg caggctcacc
    11461 ggagcggtcc acccgcacga ccgggcgcac gcctacctgc tgatgatcgg cgtccgtccc
    11521 gaccgccagg gggagggcat cggggcggag ctcatctcgg cggagctgga gcgctgcgac
    11581 cgggaggggc tgcccgtcta tctggaggcg agcagcgccc ggagccggac gctgtacgag
    11641 cggctcggat tccgcttcct cggccgggcg gtcgacctgc cggacggccc gccgatgtac
    11701 cccatgtggc gggagcccca agcgggttga tgtcggtggc aggggctaca gtccctgctc
    11761 atgacagatg agtcgtgggc cggctggtac cgggacaaca agggttccga ttccgtcgtt
    11821 ctcaccacgg acggacagcg gatccggctc cggatcagag gggccgactt cgagggtgag
    11881 agcttcgacg gcctgaggcc cgtcgcgggt gtgccgccgg agaacgggac gttcggcctg
    11941 aaggacggcg cgctcaccga ctgcgtcctg gagtgggacc agcagctgcc cgtcctcgtc
    12001 gcgggcacgc tccgccacgc cacgctcagc tgtctgctct ccctgcgccg ggccgaaccg
    12061 gatttccatc tcgccctcca cctggacggc gcggtgtacg aatcggcgcg cgccgagcgc
    12121 gacttcgccg aggcgctcgc cgccgtccag cggatccttc cgggcggcat cagccttcag
    12181 gcctgtgttg cccggtccgg agccgcctga ccctgaccct gactccgacc tcgaagtcgc
    12241 cctgccgtca ccgagcgcgt ccgccccgta ccgcatcccg gtacggggcg gatccgcgtc
    12301 gccccgccgc ctcttggccg tcttcttcgt tgcctccgcc atattgttct actagcatgc
    12361 gaacaacgga ggttttccat gacaagcaag aacgttggcc gcgtcactct cgcggccctg
    12421 ccctttgtgc tcgcactcct catcgacctc gcgctgtacg ccgccgtcgc ggaccgcctg
    12481 cccgaccggc tggccgtcca cttcgacgcc ggcggatccg ccaacggata cacgagctcc
    12541 cgttcctatc tgctctacac gctcgcctcg ctgctcgtgc tcggcgcgct gtgggtgttc
    12601 atcgcggtca agggcaggct ccgcggccgc gcccaccggt ggctcatcgg cggagggttc
    12661 gccgtggccg cgttcctcgg ctatctgctg atcgccgtcc tgttcgtcaa cgtggacgtc
    12721 cccgaaggcg gttcggccgg cgggttcccg ctcgagcaca tcgcggtggc cctcgcggcg
    12781 gccaccctcg ccggagctct cggggtgctg ctgtcccggc tggtcccgct gcccgaggac
    12841 ccccgcgacc cggacccggc gacccgggag aggctcgtgc tcgccgacgg cgaggtggcc
    12901 gcctgggggc gcggcatcgg cgcctggtgg gcacccgtcg ccgtgctggt gctgctggcg
    12961 gccggtgtca ccgtgggccg ggagcagagc tggttcatcg gagtgccgct gatcctgttc
    13021 gccctggtga cgggcacttt ctgccgcccc cacgtcaccg tggaccggcg cggcctcacc
    13081 gtctccggcc tgctgccccg gccccgggtg cgggtcccgc tggagcggat ggagggcgcg
    13141 gacagccgcc cggtcaacgc cctcgcggag tacggcggct ggggctatcg catccgcccc
    13201 gagcgcagcg gcgtcatcac ccgctcgggc gaggccatcg tcgtcagcct gacgagcggc
    13261 cgcgagttcg ccgtcaccgt cggtgactcg gccaccggcg ccgctctgct caacacgctg
    13321 ctcgaccgac agcgagcggg gcgctgacca tgctcttccg ggtcgatccg acctccaccg
    13381 tgccgctcgg ggaccagatc gccgcctcgg tccggcgcgc ggtcgccgag ggcgcggtgg
    13441 ctccgggcga gcggctgccc gccgcccggg cgctcgccga atccctcggc gtgaacgtcc
    13501 acaccgtgct gcgcggttac caacggctgc gcgaggaagg gctcatcgag ctgcgccgag
    13561 gccggggcgc ggcgatcacc gcgggcgcct cgccgcagcg cgcccggctg ctggagagag
    13621 tgcgcgaagc ggtcgccgac gcccgggacc tgggcatgac cgaggacgaa ctgctgaccc
    13681 tcgtccgtaa cgaactcgac gcctgacagg gggaggcgtc gggaatcgcg cagaggaccg
    13741 ttccggatgc ggaacggtcc tctgtcgtgt gtggcggaac ggtcctctgt cgtgtgtgtg
    13801 gggggtgccg gccgatcccg ggacacggga ccggccggac gggcgcgatg acgtcaggaa
    13861 cgcgacggcg tcaggaggcg gaacgggcga gcgaggccag accgttctgc cacagctggt
    13921 tgacgcgagc ccgctcgttg gcgtccggct gggcgttggt gcaggacggg ccggggccgc
    13981 cgccggacat caactcgctg cacgggcccg agtagttgtc cggcagaccg agcacgtgcc
    14041 cggtctcgtg cgtggtgacg cgggtcgagt cgtactgctg gttctgtgcg tagtccagga
    14101 agatgtaccc acggccgtgg ccgtcggtgc tcgcgtagga gccgcgaggg tcgttgccct
    14161 cgcggtaggt gaagtccgcg ccggagccct cctggagctg gacgttggag accgagctgt
    14221 tccagatctg cgtgctgttg gctatctggc tgcggaagga gggggcgccg gaggcgtcgt
    14281 aggtgaccgt gacggccttg atgccggggt tggccgcgcg cttctcggcg acggacttca
    14341 tgaccgcgtc gaggaaggcg cggttggcgg cggcgttctc gccggagccg ttgtacgcgg
    14401 cgatggtgga ggaggcggaa ggggcggcag gggccggagc ggcgacggcg accggtgcgg
    14461 tgcccagcgc ggcgacgagg ccgagcccgg cggcggcggt ggcgacggcg ttcttgaggt
    14521 gtctcatggg gggatttctc ctacctgtcc gaacgaaccc acgccgtggg ggtgtccgct
    14581 gaacggacaa gacgtggggt ggtacgagga agagtgtggt gcagcgcaca gcagtcgggg
    14641 atgatgccgg acggcgatag cgccgcccta tcgccgccag gtcccttctc tctgcgcacg
    14701 tcagccgctt acggtcatgc catgcccacg tcatcattac ggcatcgcca cagtcctccg
    14761 ggaccaacac tccctgaatt gatgctgttt ggtggggttg cgacgtctgg tgcgcggcgg
    14821 acggcagtca tagtctccgc tgcatggagc tggaggtgag gcacctcaag gcgctgtgcg
    14881 ccatcgccga cgcgggcagt ctgcaccagg cggcccgtcg cctcggcgtg agccagccct
    14941 ccctgacgac ccagctgcaa cggatcgaga acgttctcgg cgccgagctg ttcctccgcg
    15001 aacggaccgg ctgccgcccg acctccctgg ggcgcgccgt cctgagccgg gcccggcccc
    15061 tcgtcgacgg catgagcgac ctggtcgccg cggcgctggc ggaggccgag gccgcccggc
    15121 cccgcggctc ccggctgcgc atcggctcga ccgcgagccg ggtcatcggc ggctggctgc
    15181 gccggctgcg gatcgccctg cccggtacgg acatctccct gcgggtcgac gtctccgccc
    15241 acgagctgct gcgctcggtc gctgcggggc gcctggacgt cgccttcgtg cacgaggtgg
    15301 agggctgccc gctgacgctg ccggagggcc tggaacagcg cgtactcgtg gaccgggaac
    15361 cgcagttcat ctccctctcg cgggaccacc cggccgcccg ccgtcgcgtg gtggagctcg
    15421 gcgatctggc gggcgacccg tggatggtcg atccgacggt ggacggcgag tgggacgggg
    15481 tgcgccgggt gctcggcgcc gccggactga acccgccggt cctgcacggc gactacctca
    15541 ccgccgcctc cctcgtcgtg ctcggcgagg cggtggcccc ctgccagccg acgtcgggcc
    15601 cgcgcgacga catggtgatc cgcccgctgc tgggcgatcc gctcgccgtg cgcctcctcc
    15661 tggtgtcccg gcccgggacc gacatcgagg tggtgtacgc gcagttggag gacgcctacc
    15721 gggacgcggc gcgacgggcg agcggctacc acgagtggct gctgcgccac cgctccccgc
    15781 tggcccgtac gtcctgaccc gcacggttcc gtcggcccgt cggctgcgga gagttccccg
    15841 ttctgctgac agcgtgcccg ggttccgcca ccgcccgccg atgggcagag tcgttccatg
    15901 aggcttctga tgctgggcgg tacggagttc gtcggacggg ccgtcaccga cgcggcgctg
    15961 gagcggggct gggatgtcac ggtgttccac cgcggccacc acgcgccccc gcccggcgtg
    16021 agcgcgctga ccggggaccg gaccacgggc gagcgggggc tcgcggcgct ggcggaaagc
    16081 gggcgggact gggacctggt cgtcgacacc tggagcggcg ccccggccgc cgtccgggat
    16141 gccgcccgtc tgctgtccgg ccgggcggga cacttcagtt acgtctccag ccgttcggtg
    16201 tacgcccacc cggccgcccc cggactcgac gaggaaggtc cgctggtgac cggcgcctct
    16261 cccgacgacg gcggcgacgt gccgtacgac cgggccaagc gcggcggcga gctggccgcc
    16321 ctcgaagcct tcggggaccg ggccatgctg gcgcgggccg ggctgatcat cggccccggc
    16381 gagaacatcg gccgccttcc ctggtggctg tcgcgcatcg accgcggcgg acccgtgatc
    16441 gcccccggcc ggcccgacgt ggagctccag tacatcgacg cccgggacct ggcggtgtgg
    16501 atcctggacg cggcggcgga cgggctgcac ggcgcgtaca acaccgtcag ccgccccggc
    16561 cacgcgacca tgggcgagct gctggaggcc tgtgtgcgga ccaccggttc cgacgccgag
    16621 ctgcgctgga ccgatccgga ggtcctgctg gccgccgggg ccgagccctg gagcgacctg
    16681 ccgatctggc tgccgccggg cgagctgtac gacacgctcc accggggcga ccacaccaag
    16741 gcgtacgcgg cggggctgcg ctgccgcccg gtggaggaga ccgtcgcgga cacctggacc
    16801 tggctgcgcg cgctcggcgg caccgcgccc cgccgccccg accgcccggc cgtcggcctc
    16861 gaccccggcc tggaggcgaa gctgctggcg ctctgacggc tgctgacgaa ccggagtcct
    16921 gacactccgc cgctccgaca tgccactcgc gtgcgcgtgt cgcccgaaga aaccacccat
    16981 aggcctacgt aaccgggcaa gagcggcgtg tcatacaaaa cgacaaagtg atgaccatgc
    17041 atattgcgcg gcatggaaca gaaggcgcgc aggcgcggca acgcaatccg ggcagcagtg
    17101 acagtggcca cggccgcggc gatggtgggc gtgctggccc cggccgcggg ggccgatccg
    17161 ctgccgggcg gactgggacc ctgcctcggc agctcctgcc cgcccagctg gaacgacccc
    17221 aacaaccttc cggtcgtcgg cttcgacagc aacatcaacg tcttcgtcgg cggggacttc
    17281 ctggtccgcg aggcggcggc cgaggctgag ggcaaggtcg tcacgctcgg cgagttcgac
    17341 atgaacaagc gggcgggggt ctctcaggtc tacaacgtcg gtatcgcggg cgtcggttcg
    17401 cgggtgccgc cgccggacgg ctccgactat ctgacgacgg gcggggacgt caccatcgcc
    17461 gacggtcagc gactcctcgc ggaggagggc gagcactccg gccgagtcgc gtacgcgggg
    17521 gagctcacgg gcacggtgaa ccccaccacc gccccgcgct tcgacgagga cgcggcggcc
    17581 ccgtacaccc agctgcgccc gcagctcacc gaggccagtc agtgctacgc gtacgacggc
    17641 gacgagcacc gggaagcgac gggcacgtgg cagcaggtcg gtgacgtcat gaccttcacc
    17701 ggcgacggca cgtccgcgat ccagatcttc gacgtggacg tggacctgga gtcggaggcg
    17761 ggcggcaaca cggggttcgt gttcaacggg attcccgcgg gtgcgaccgt cctggtcaac
    17821 gtgtacggca gcacgcgcag cgtcgccacg ttcatgggct cgttccccaa cgagggcctc
    17881 cgcgagaacc tgctgtggaa cttcccggac gccaccgatc tgtcgctgac gggcccggcc
    17941 cagttcgagg gcagcgttct ggtcggccag ccgacgagca gcaccgtact cagcatgagc
    18001 ggtaccaacg gccgcttcta cacggcgggt tcgctcaccc acacctcgca gggccagtcg
    18061 ggcggccagg agatccacgc gtaccccttc gacggggacc tgccgtcgtg cacccccgac
    18121 ccgactcnnn nnnnnnnnnn nnnnnnnnnn nncgacgccg acgcccacgg aaccgacgcc
    18181 gaccccgacg gacccgacgc ccacgccgac ggaccccacc ccgaccccga ccgagccgac
    18241 gccgaccccc acccaccaca cgccgcgccc cacgcactcg ccgagccacc cgggtgagct
    18301 gcccgacacc ggctcccggg gcggcgaatg gatcatcggg tccatcgcgg cagcgctggt
    18361 ggccgccggc ggtacggttc tcgtggccac gcgcagggct cgtcgccgca ccttctgacc
    18421 ggcgcgaagc agcgcccgct agcgtggttc gatgaccgaa ccgctgctgc acctcgccga
    18481 agcgcctctg tgggaggcgg cccgcgggac agggacgtac gagatgtcca cccgcggccg
    18541 caccctccag gaggagggct tcatccatct ctcgctgccc cgccaactcc ccggtgtggc
    18601 acggatgctg tacggggacg acgaccggga cctcgtggtc ctggtcgtcg accccggccg
    18661 cctcgccgat cccgtccggt acgaggcgat gaagcccggc ggcgaggagt tcccgcacct
    18721 gtacggaccg ctccccgtgg gcgcggtcgt cgaggtgcgg cgccttgccg actggtacca
    18781 cgaccgacga gaggaagacg aaccccagtg atcggccccc tcaccgcggt gaccggagcg
    18841 agcggagcgg tcggtggccg ggtcgcccga cggctggccc gcaccggcgt ccccgtacgg
    18901 ctcctcggcc gcgaccccgc ccggctgccc gacgtgcccg gcgccgaccg agcgcccgcc
    18961 gccccctacg gcgacgggga ggccatgcgc cgcgccctcg acggagccca caccctgttc
    19021 ctggtctccg cccacgagag cccgtaccgg gtccgcgagc acaccaccgc catcgacgcg
    19081 gccgtggcgg tgggggtgga gcggatcgtg tacgtctcct tccaaggagc cgcgcccgac
    19141 gccacgttca ccttcgcccg tgaccactgg gacaccgagg cccacatccg taccgccgag
    19201 atccgccaca ccttcctgcg ggacaactgg tacctcgcgg ggctgcccgc gatgaccggg
    19261 accgacggtg tcctgcgcgg acccggcggc gacgggcggg tggcggccgt cgcccacgag
    19321 gacatcgccg acgcggcggc ggccgtcctg ctggacgagg gcacggacca cgacggccgg
    19381 gtctacgacc tcacaggacc ggaggcgttc accctcgccg aggcggccga cgagctgagc
    19441 cgggtcaccg ggcggcccgt cgtctacgtc cccgagaccc gggaggaggc ctacgcctcc
    19501 cgggccggct acggggccga ggactgggaa gtggccggct gggtcacctc ctacgaggcc
    19561 atcgccaacg gcgaactggc cgccgtctcc gacgcggtgc ccacgctcac cgggcgcccg
    19621 gcgcagagct tcgcccagtt cctggtggag aacccggaca gttaccgcca tctgctcccc
    19681 ggcggctgac cgggagaccc ccgtctcagc gccacgggat gtgacgccac ggactgccct
    19741 cgctctccgt cagcagacgg tgggcgagga cgttctgttc gtagaacggc ccgtactcct
    19801 cgtcgtcgaa ccgcagcacc cgccccagcg cgtacccggc ggagaactcc tcccacgagc
    19861 ggtacgccga cttgctcagc gccccggcgt acacgatcgc cgcctcggcg tcggccggac
    19921 cgcagaaccg cgccgacaac ccccagcgcg ccaggttcac ggcccgcccg tagtcgtacg
    19981 cgaccgtcgt gcgcacccgg ccgtccggcg gcagcagccc gtccgcgcgg aaccgggcct
    20041 cgtagcgcat gatccggcgc accaggtccg cgatgccctt gaccgtgctc gcatcggccc
    20101 cgaggtcctg ggcgtgaccg gcggcggtct cccgccacag gtcggccgag ggcagttcgc
    20161 cgatggccgc cgtcaactgc tcgcgggcgc gcagcgcgaa gtcaggttcc ggcgggctgt
    20221 tggccgcgtc cagcaggaag tccagctgcc ggcgccatcc ctcgtggtcg gtgatgcccc
    20281 aggagtcgcg gagttgttcg cgctcgtcga cgtactcgcg gtagacggtg ccgatctcgt
    20341 tccacgggac ggcgttcccg atcgccagat gcgccccgca ggccaggcca tacgccagcg
    20401 gaccgtggag cgcgccgtgc cgcagcgcga cgagccggtt gccggacgcc cggtcgttct
    20461 ccgcgtacgc ccgctgccac agggccaggt cgggcggggc ggtgggcagc agcaactgac
    20521 cgggcgttcc cacgttcacg cccagccaca cctgcggatc gctccagccg aactcggcga
    20581 tccaccgcag cgagaccccg cggaagaccc agtccgggtg ccacgcgggc agcatgcccc
    20641 gggtgaggag cggccggcag acgaagcccg ccgggtcgac gtgccgccgc cacatcacgg
    20701 tgtccggatc ggcgtccacc tcggcgcgtg gggccgggat gtacagctcg gtcccggcca
    20761 gcgcggccag ttgaccccgt acgtcgccgc gcagggcggc ctcgtggagg agctgctcgg
    20821 tctcggaggg cgggacccag ggggcggggg cagccggggg agccgagggg tggatcgggt
    20881 ggatcgggtt catgaccacg cgatgttcct gtaggggccg gcggggtcct gggtcagggt
    20941 gcggtgttcg gcgagcgact gtcggtacgt ggcctccgcc gcctccgggc cgtcgtcctc
    21001 cgcgcggtgg accaggcggg ccatgaggta gccgagggag aagt
//
